TRPA

1

Touska F et al. Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay.
Temperature (Austin), 2016 Jan-Mar , 3 (77-91).

2

Andrei SR et al. TRPA1 is functionally co-expressed with TRPV1 in cardiac muscle: Co-localization at z-discs, costameres and intercalated discs.
Channels (Austin), 2016 May 4 , (1-15).

3

McEntire DM et al. Pain transduction: a pharmacologic perspective.
Expert Rev Clin Pharmacol, 2016 May 23 , (1-12).

4

Babes A et al. Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.
J. Neurosci., 2016 May 11 , 36 (5264-78).

5

Karaki S et al. Effects of ε-viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa.
Physiol Rep, 2016 May , 4 ().

6

Cooper BY et al. Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors.
Neurotoxicology, 2016 May , 54 (99-110).

7

Shapiro H et al. Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation.
Prostaglandins Leukot. Essent. Fatty Acids, 2016 Mar 9 , ().

8

Bertin S et al. The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1.
Gut, 2016 Jun 20 , ().

9

Payrits M et al. A novel 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime compound is a potent Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and V1) receptor antagonist.
Neuroscience, 2016 Jun 2 , 324 (151-62).

10

Meents JE et al. Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.
J. Physiol. (Lond.), 2016 Jun 16 , ().

11

Bahia PK et al. The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1.
J. Gen. Physiol., 2016 Jun , 147 (451-65).

12

Hamilton NB et al. Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia.
Nature, 2016 Jan 28 , 529 (523-7).

13

Verma VA et al. α-Aryl pyrrolidine sulfonamides as TRPA1 antagonists.
Bioorg. Med. Chem. Lett., 2016 Jan 15 , 26 (495-8).

14

Borkum JM Migraine Triggers and Oxidative Stress: A Narrative Review and Synthesis.
Headache, 2016 Jan , 56 (12-35).

15

Mistretta FA et al. DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.
J. Pharmacol. Exp. Ther., 2016 Jan , 356 (200-11).

16

Snyder LM et al. An Unexpected Role for TRPV4 in Serotonin-Mediated Itch.
J. Invest. Dermatol., 2016 Jan , 136 (7-9).

17

Du EJ et al. TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.
PLoS Genet., 2016 Jan , 12 (e1005773).

18

Stueber T et al. Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity.
Anesthesiology, 2016 Feb 9 , ().

19

Ohya S et al. Recent advances in therapeutic strategies that focus on the regulation of ion channel expression.
Pharmacol. Ther., 2016 Feb 16 , ().

20

Das A et al. dTRPA1 in Non-circadian Neurons Modulates Temperature-Dependent Rhythmic Activity in Drosophila melanogaster.
J. Biol. Rhythms, 2016 Feb 11 , ().

21

El Karim IA et al. Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells.
J Endod, 2016 Feb 10 , ().

22

Brozmanova M et al. Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers.
Am. J. Physiol. Gastrointest. Liver Physiol., 2016 Feb 1 , 310 (G215-23).

23

Chen S et al. TRP channel mediated neuronal activation and ablation in freely behaving zebrafish.
Nat. Methods, 2016 Feb , 13 (147-50).

24

Ferreira LG et al. TRPing on the pore phenomenon: what do we know about transient receptor potential ion channel-related pore dilation up to now?
J. Bioenerg. Biomembr., 2016 Feb , 48 (1-12).

25

Kang K Exceptionally high thermal sensitivity of rattlesnake TRPA1 correlates with peak current amplitude.
Biochim. Biophys. Acta, 2016 Feb , 1858 (318-25).

26

Murphy TV et al. TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats.
Vascul. Pharmacol., 2016 Apr 9 , ().

27

Devos FC et al. Neuro-immune interactions in chemical-induced airway hyperreactivity.
Eur. Respir. J., 2016 Apr 28 , ().

28

Moriello AS et al. Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo.
CNS Neurol Disord Drug Targets, 2016 Apr 13 , ().

29

Jian T et al. TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch.
Neural Plast., 2016 , 2016 (1682972).

30

Soldano A et al. Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila.
Elife, 2016 , 5 ().

31

Kanju P et al. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.
Sci Rep, 2016 , 6 (26894).

32

Wu X et al. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 , 11 (e0155577).

33

Thies J et al. Differential Effects of TRPA and TRPV Channels on Behaviors of Caenorhabditis elegans.
J Exp Neurosci, 2016 , 10 (71-5).

34

da Silva Serra I et al. Characterization of cutaneous and articular sensory neurons.
Mol Pain, 2016 , 12 ().

35

Zappia KJ et al. Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes.
PLoS ONE, 2016 , 11 (e0151602).

36

Ückert S et al. Expression and distribution of the transient receptor potential cationic channel ankyrin 1 (TRPA1) in the human vagina.
Int. J. Impot. Res., 2015 Jan-Feb , 27 (16-9).

37

Chen J The evolutionary divergence of TRPA1 channel: heat-sensitive, cold-sensitive and temperature-insensitive.
Temperature (Austin), 2015 Apr-Jun , 2 (158-9).

38

Laursen WJ et al. Species-specific temperature sensitivity of TRPA1.
Temperature (Austin), 2015 Apr-Jun , 2 (214-26).

39

Ji RR Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms?
Pulm Pharmacol Ther, 2015 Sep 6 , ().

40

Pradhananga S et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.
Eur. J. Pharmacol., 2015 Sep 5 , 762 (313-21).

41

Tatsumi E et al. Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury.
Neuroreport, 2015 Sep 30 , 26 (856-61).

42

Paulsen CE et al. Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 2015 Sep 24 , 525 (552).

43

Asgar J et al. The role of TRPA1 in muscle pain and mechanical hypersensitivity under inflammatory conditions in rats.
Neuroscience, 2015 Sep 21 , 310 (206-215).

44

Brewster MS et al. How the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopy.
Bioessays, 2015 Sep 21 , ().

45

Dai Y TRPs and pain.
Semin Immunopathol, 2015 Sep 15 , ().

46

Billeter AT et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Surgery, 2015 Sep , 158 (646-54).

47

De Petrocellis L et al. Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel.
Pharmacol. Res., 2015 Sep , 99 (362-9).

48

Stenger B et al. Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents.
Arch. Toxicol., 2015 Sep , 89 (1631-43).

49

Nishimoto R et al. Propofol-induced pain sensation involves multiple mechanisms in sensory neurons.
Pflugers Arch., 2015 Sep , 467 (2011-20).

50

Xu ZH et al. Action of thymol on spontaneous excitatory transmission in adult rat spinal substantia gelatinosa neurons.
Neurosci. Lett., 2015 Oct 8 , 606 (94-9).

51

Ujike A et al. Bidirectional effects of hydrogen sulfide via ATP-sensitive K(+) channels and transient receptor potential A1 channels in RIN14B cells.
Eur. J. Pharmacol., 2015 Oct 5 , 764 (463-70).

52

Oda M et al. Chemical sensing properties of Takifugu TRPA1.
Neuroreport, 2015 Oct 21 , 26 (908-14).

53

Kichko TI et al. Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Oct 15 , 309 (L812-20).

54

Yu X et al. TRP channel functions in the gastrointestinal tract.
Semin Immunopathol, 2015 Oct 12 , ().

55

Patel R et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci., 2015 Oct 10 , ().

56

Hulse RP et al. Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.
Clin. Sci., 2015 Oct 1 , 129 (741-56).

57

Patricio ES et al. Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice.
J. Invest. Dermatol., 2015 Oct , 135 (2484-91).

58

Barbagallo B et al. Temperature sensation in Drosophila.
Curr. Opin. Neurobiol., 2015 Oct , 34 (8-13).

59

Moilanen LJ et al. Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis.
Osteoarthr. Cartil., 2015 Nov , 23 (2017-26).

60

Okada Y et al. Transient Receptor Potential Channels and Corneal Stromal Inflammation.
Cornea, 2015 Nov , 34 Suppl 11 (S136-41).

61

El Karim I et al. TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells.
Am. J. Pathol., 2015 Nov , 185 (2994-3002).

62

Mollanazar NK et al. Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?
Clin Rev Allergy Immunol, 2015 May 1 , ().

63

Witschas K et al. Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane.
Biochim. Biophys. Acta, 2015 May , 1848 (1147-56).

64

Kim HG et al. The roles of thermal transient receptor potential channels in thermotactic behavior and in thermal acclimation in the red flour beetle, Tribolium castaneum.
J. Insect Physiol., 2015 May , 76 (47-55).

65

Horváth G et al. Effects of some natural carotenoids on TRPA1- and TRPV1-induced neurogenic inflammatory processes in vivo in the mouse skin.
J. Mol. Neurosci., 2015 May , 56 (113-21).

66

Zhou HR et al. Deoxynivalenol (Vomitoxin)-Induced Cholecystokinin and Glucagon-Like Peptide-1 Release in the STC-1 Enteroendocrine Cell Model is Mediated by Calcium-Sensing Receptor and Transient Receptor Potential Ankyrin-1 Channel.
Toxicol. Sci., 2015 Mar 18 , ().

67

Gualdani R et al. Lipoic-based TRPA1/TRPV1 antagonist to treat orofacial pain.
ACS Chem Neurosci, 2015 Mar 18 , 6 (380-5).

68

Iosub AV et al. Palladium-catalyzed aerobic oxidative dehydrogenation of cyclohexenes to substituted arene derivatives.
J. Am. Chem. Soc., 2015 Mar 18 , 137 (3454-7).

69

Liu Z et al. Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Mar 15 , 308 (G482-8).

70

Del Prete D et al. Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands.
Bioorg. Med. Chem. Lett., 2015 Mar 1 , 25 (1009-11).

71

Liu BY et al. Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8.
J. Appl. Physiol., 2015 Mar 1 , 118 (635-45).

72

Jha A et al. A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?
Can. J. Physiol. Pharmacol., 2015 Mar , 93 (171-6).

73

Urata K et al. Involvement of TRPV1 and TRPA1 in incisional intraoral and extraoral pain.
J. Dent. Res., 2015 Mar , 94 (446-54).

74

Peng G et al. Evolution of TRP channels inferred by their classification in diverse animal species.
Mol. Phylogenet. Evol., 2015 Mar , 84 (145-57).

75

Sałat K et al. Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
J Zhejiang Univ Sci B, 2015 Mar , 16 (167-78).

76

Zhang B et al. Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel.
Cell Rep, 2015 Jun 9 , 11 (1414-24).

77

Wang W et al. Off-response in ASH neurons evoked by CuSO4 requires the TRP channel OSM-9 in Caenorhabditis elegans.
Biochem. Biophys. Res. Commun., 2015 Jun 5 , 461 (463-8).

78

Hsu CC et al. Role of calcium ions in the positive interaction between TRPA1 and TRPV1 channels in bronchopulmonary sensory neurons.
J. Appl. Physiol., 2015 Jun 15 , 118 (1533-43).

79

Andersson DA et al. Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.
J. Biol. Chem., 2015 Jun 12 , 290 (15185-96).

80

Benemei S et al. TRP channels.
Curr Opin Pharmacol, 2015 Jun , 22 (18-23).

81

Mori Y et al. Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation.
Pflugers Arch., 2015 Jul 7 , ().

82

Green EW et al. Drosophila circadian rhythms in seminatural environments: Summer afternoon component is not an artifact and requires TrpA1 channels.
Proc. Natl. Acad. Sci. U.S.A., 2015 Jul 14 , 112 (8702-7).

83

Peng G et al. Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1.
Cell Rep, 2015 Jul 14 , 12 (190-202).

84

Morita T et al. HTR7 Mediates Serotonergic Acute and Chronic Itch.
Neuron, 2015 Jul 1 , 87 (124-38).

85

Meng Q et al. Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers.
Am. J. Physiol., Cell Physiol., 2015 Jul 1 , 309 (C1-10).

86

Sherkheli MA et al. Borneol inhibits TRPA1, a proinflammatory and noxious pain-sensing cation channel.
Pak J Pharm Sci, 2015 Jul , 28 (1357-63).

87

Kimball C et al. The Pore Loop Domain of TRPV1 Is Required for Its Activation by the Volatile Anesthetics Chloroform and Isoflurane.
Mol. Pharmacol., 2015 Jul , 88 (131-8).

88

Deberry JJ et al. Artemin Immunotherapy Is Effective in Preventing and Reversing Cystitis-Induced Bladder Hyperalgesia via TRPA1 Regulation.
J Pain, 2015 Jul , 16 (628-36).

89

Zhu Y et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Br. J. Pharmacol., 2015 Jul , 172 (3495-509).

90

Nassini R et al. The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Br. J. Pharmacol., 2015 Jul , 172 (3397-411).

91

Sullivan MN et al. Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Sci Signal, 2015 Jan 6 , 8 (ra2).

92

Ohara K et al. Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil.
J. Biol. Chem., 2015 Jan 30 , 290 (3161-71).

93

Palkar R et al. The molecular and cellular basis of thermosensation in mammals.
Curr. Opin. Neurobiol., 2015 Jan 23 , 34C (14-19).

94

Pinheiro Fde V et al. The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain.
Eur. J. Pharmacol., 2015 Jan 15 , 747 (105-13).

95

Canner JP et al. Developmental regulation of trigeminal TRPA1 by the cornea.
Invest. Ophthalmol. Vis. Sci., 2015 Jan , 56 (29-36).

96

Lindsay CD et al. Potency of irritation by benzylidenemalononitriles in humans correlates with TRPA1 ion channel activation.
R Soc Open Sci, 2015 Jan , 2 (140160).

97

Huang BX et al. [Expressions of transient receptor potential A1 and related inflammatory factors in the rat model of prostatic inflammation].
Zhonghua Nan Ke Xue, 2015 Jan , 21 (23-30).

98

Kurogi M et al. Auto-oxidation products of epigallocatechin gallate activate TRPA1 and TRPV1 in sensory neurons.
Chem. Senses, 2015 Jan , 40 (27-46).

99

Yang YS et al. Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus.
Acta Derm. Venereol., 2015 Jan , 95 (20-4).

100

Zíma V et al. Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.
Neuropharmacology, 2015 Feb 25 , 93C (294-307).

101

Yrbas ML et al. Pharmacological mechanism underlying the antinociceptive activity of vanillic acid.
Pharmacol. Biochem. Behav., 2015 Feb 21 , 132 (88-95).

102

Weyer AD et al. Loosening Pain's Grip by Tightening TRPV1-TRPA1 Interactions.
Neuron, 2015 Feb 18 , 85 (661-3).

103

Weng HJ et al. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Neuron, 2015 Feb 18 , 85 (833-46).

104

Lin YJ et al. A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents.
J. Appl. Physiol., 2015 Feb 1 , 118 (273-81).

105

Kichko TI et al. Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea.
Anesth. Analg., 2015 Feb , 120 (467-71).

106

Zielińska M et al. Role of transient receptor potential channels in intestinal inflammation and visceral pain: novel targets in inflammatory bowel diseases.
Inflamm. Bowel Dis., 2015 Feb , 21 (419-27).

107

Srebro DP et al. TRPA1, NMDA receptors and nitric oxide mediate mechanical hyperalgesia induced by local injection of magnesium sulfate into the rat hind paw.
Physiol. Behav., 2015 Feb , 139 (267-73).

108

Terada Y et al. Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis.
J. Neurosci. Res., 2015 Feb , 93 (361-9).

109

Silva RB et al. Spinal blockage of P/Q- or N-type voltage-gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis in mice.
Br. J. Pharmacol., 2015 Feb , 172 (924-39).

110

Hooper JS et al. Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin and ATP in Sprague Dawley rats.
J. Appl. Physiol., 2015 Dec 30 , (jap.00944.2015).

111

Pires PW et al. Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.
Am. J. Physiol. Heart Circ. Physiol., 2015 Dec 15 , 309 (H2031-41).

112

Bais S et al. Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni.
PLoS Negl Trop Dis, 2015 Dec , 9 (e0004295).

113

Park J et al. Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
J. Neurochem., 2015 Dec , 135 (987-97).

114

Deering-Rice CE et al. Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma.
Am. J. Respir. Cell Mol. Biol., 2015 Dec , 53 (893-901).

115

Terada Y et al. Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard.
J. Nat. Prod., 2015 Aug 28 , 78 (1937-41).

116

Nozadze I et al. Role of thermo TRPA1 and TRPV1 channels in heat, cold, and mechanical nociception of rats.
Behav Pharmacol, 2015 Aug 13 , ().

117

Zou Q et al. Transient Receptor Potential Channel Opening Releases Endogenous Acetylcholine, which Contributes to Endothelium-Dependent Relaxation Induced by Mild Hypothermia in Spontaneously Hypertensive Rat but Not Wistar-Kyoto Rat Arteries.
J. Pharmacol. Exp. Ther., 2015 Aug , 354 (121-30).

118

Cenac N et al. Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.
Gastroenterology, 2015 Aug , 149 (433-44.e7).

119

Carpi S et al. AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells.
Anticancer Drugs, 2015 Aug , 26 (754-62).

120

Tani M et al. Long-lasting facilitation of respiratory rhythm by treatment with TRPA1 agonist, cinnamaldehyde.
J. Neurophysiol., 2015 Aug , 114 (989-98).

121

Wei JJ et al. A TRPA1 channel that senses thermal stimulus and irritating chemicals in Helicoverpa armigera.
Insect Mol. Biol., 2015 Aug , 24 (412-21).

122

Paulsen CE et al. Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 2015 Apr 8 , ().

123

Shi HL et al. Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction.
World J. Gastroenterol., 2015 Apr 28 , 21 (4852-63).

124

Clapham DE Structural biology: Pain-sensing TRPA1 channel resolved.
Nature, 2015 Apr 23 , 520 (439-41).

125

Uvin P et al. Essential Role of Transient Receptor Potential M8 (TRPM8) in a Model of Acute Cold-induced Urinary Urgency.
Eur. Urol., 2015 Apr 2 , ().

126

Katagiri A et al. Evidence for TRPA1 involvement in central neural mechanisms in a rat model of dry eye.
Neuroscience, 2015 Apr 2 , 290 (204-13).

127

Kang Q et al. Spontaneous L-glutamate release enhancement in rat substantia gelatinosa neurons by (-)-carvone and (+)-carvone which activate different types of TRP channel.
Biochem. Biophys. Res. Commun., 2015 Apr 10 , 459 (498-503).

128

Kubota K et al. Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Apr 1 , 308 (G579-90).

129

Bonvini SJ et al. Targeting TRP channels for chronic cough: from bench to bedside.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Apr , 388 (401-20).

130

Li F et al. Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice.
Anesthesiology, 2015 Apr , 122 (768-75).

131

Miyano K et al. Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
Anesth. Analg., 2015 Apr , 120 (790-8).

132

Lehto SG et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Apr , 388 (465-76).

133

Chen J et al. TRPA1 as a drug target--promise and challenges.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Apr , 388 (451-63).

134

Son GY et al. Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.
Arch. Oral Biol., 2015 Apr , 60 (526-32).

135

Shibukawa Y et al. Odontoblasts as sensory receptors: transient receptor potential channels, pannexin-1, and ionotropic ATP receptors mediate intercellular odontoblast-neuron signal transduction.
Pflugers Arch., 2015 Apr , 467 (843-63).

136

Moilanen LJ et al. Urate crystal induced inflammation and joint pain are reduced in transient receptor potential ankyrin 1 deficient mice - potential role for transient receptor potential ankyrin 1 in gout.
PLoS ONE, 2015 , 10 (e0117770).

137

Wang C et al. Wu-Tou Decoction Inhibits Chronic Inflammatory Pain in Mice: Participation of TRPV1 and TRPA1 Ion Channels.
Biomed Res Int, 2015 , 2015 (328707).

138

Sinha S et al. Propofol Causes Vasodilation In Vivo via TRPA1 Ion Channels: Role of Nitric Oxide and BKCa Channels.
PLoS ONE, 2015 , 10 (e0122189).

139

Kozai D et al. Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels.
Curr Neuropharmacol, 2015 , 13 (266-78).

140

Morgan K et al. Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.
Biosci. Rep., 2015 , 35 ().

141

Liu C et al. Cell cycle control, DNA damage repair, and apoptosis-related pathways control pre-ameloblasts differentiation during tooth development.
BMC Genomics, 2015 , 16 (592).

142

Das A et al. dTRPA1 Modulates Afternoon Peak of Activity of Fruit Flies Drosophila melanogaster.
PLoS ONE, 2015 , 10 (e0134213).

143

Carson C et al. Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
PLoS ONE, 2015 , 10 (e0127498).

144

Belmonte C et al. What Causes Eye Pain?
Curr Ophthalmol Rep, 2015 , 3 (111-121).

145

Lötsch J et al. Multimodal distribution of human cold pain thresholds.
PLoS ONE, 2015 , 10 (e0125822).

146

Kurohane K et al. Adjuvant Effect of an Alternative Plasticizer, Diisopropyl Adipate, on a Contact Hypersensitivity Mouse Model: Link with Sensory Ion Channel TRPA1 Activation.
Biol. Pharm. Bull., 2015 , 38 (1054-62).

147

Watanabe T et al. Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods.
J. Nutr. Sci. Vitaminol., 2015 , 61 Suppl (S86-8).

148

Mancuso G et al. Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.
Molecules, 2015 , 20 (18907-22).

149

Gallego-Martin T et al. Experimental Observations on the Biological Significance of Hydrogen Sulfide in Carotid Body Chemoreception.
Adv. Exp. Med. Biol., 2015 , 860 (9-16).

150

Terada Y et al. H2S and Pain: A Novel Aspect for Processing of Somatic, Visceral and Neuropathic Pain Signals.
Handb Exp Pharmacol, 2015 , 230 (217-30).

151

Park JH et al. Oxaliplatin-Induced Peripheral Neuropathy via TRPA1 Stimulation in Mice Dorsal Root Ganglion Is Correlated with Aluminum Accumulation.
PLoS ONE, 2015 , 10 (e0124875).

152

Fischer MJ et al. Formalin evokes calcium transients from the endoplasmatic reticulum.
PLoS ONE, 2015 , 10 (e0123762).

153

Camacho S et al. Anti-obesity and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin secretion and functional impact on food intake and gastric emptying.
Sci Rep, 2015 , 5 (7919).

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