Kir2.1
1111 literature references associated to Kir2.1
1
Swale DR
et al.
ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
ACS Chem Neurosci,
2016
May
24
, ().
2
Hsieh CP
et al.
The mechanism of inward rectification in Kir channels: A novel kinetic model with non-equilibrium thermodynamics approach.
Biophys. Chem.,
2016
May
, 212 (1-8).
3
Ye W
et al.
The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.
Proc. Natl. Acad. Sci. U.S.A.,
2016
Jan
12
, 113 (E229-38).
4
Adams DS
et al.
Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome.
J. Physiol. (Lond.),
2016
Feb
10
, ().
5
Crumb WJ
et al.
An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel.
J Pharmacol Toxicol Methods,
2016
Apr
6
, ().
6
Asmar A
et al.
Membrane channel gene expression in human costal and articular chondrocytes.
Organogenesis,
2016
Apr
2
, 12 (94-107).
7
Touhara KK
et al.
The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers.
Elife,
2016
, 5 ().
8
Siddiqui TA
et al.
Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia.
J Neuroinflammation,
2016
, 13 (66).
9
Climent AM
et al.
The Role of Atrial Tissue Remodeling on Rotor Dynamics: An In-Vitro Study.
Am. J. Physiol. Heart Circ. Physiol.,
2015
Sep
25
, (ajpheart.00055.2015).
10
Kim KS
et al.
Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease.
J. Immunol.,
2015
Oct
1
, 195 (3345-54).
11
Wu Y
et al.
Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2015
Oct
, 309 (R747-56).
12
Yakubovich D
et al.
A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.
PLoS Comput. Biol.,
2015
Nov
, 11 (e1004598).
13
Kotecki L
et al.
GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner.
J. Neurosci.,
2015
May
6
, 35 (7131-42).
14
Liu XL
et al.
Case report: A Chinese child with Andersen-Tawil syndrome due to a de novo KCNJ2 mutation.
J. Neurol. Sci.,
2015
May
15
, 352 (105-6).
15
Buck TM
et al.
The expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae.
Physiol. Genomics,
2015
Mar
10
, (physiolgenomics.00101.2014).
16
DiFranco M
et al.
Inward rectifier potassium currents in mammalian skeletal muscle fibres.
J. Physiol. (Lond.),
2015
Mar
1
, 593 (1213-38).
17
Hasegawa K
et al.
Mosaic KCNJ2 mutation in Andersen-Tawil syndrome: targeted deep sequencing is useful for the detection of mosaicism.
Clin. Genet.,
2015
Mar
, 87 (279-83).
18
Miyamoto K
et al.
Efficacy and safety of flecainide for ventricular arrhythmias in patients with Andersen-Tawil syndrome with KCNJ2 mutations.
Heart Rhythm,
2015
Mar
, 12 (596-603).
19
Kang S
The Role of Casein Kinase 2 in Ion Channel Remodeling After Myocardial Infarction. Editorial to: "Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2" by Xinran Li et al.
Cardiovasc Drugs Ther,
2015
Jun
, 29 (207-8).
20
Jugdutt BI
Suppression of Ventricular Arrhythmias After Myocardial Infarction by AT1 Receptor Blockade: Role of the AT2 Receptor and Casein Kinase 2/Kir2.1 Pathway. Editorial to: "Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction Via Casein K
Cardiovasc Drugs Ther,
2015
Jun
, 29 (201-6).
21
Li X
et al.
Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2.
Cardiovasc Drugs Ther,
2015
Jun
, 29 (209-18).
22
Harrell DT
et al.
Genotype-dependent differences in age of manifestation and arrhythmia complications in short QT syndrome.
Int. J. Cardiol.,
2015
Jul
1
, 190 (393-402).
23
Hsieh CP
et al.
Driving force-dependent block by internal Ba(2+) on the Kir2.1 channel: Mechanistic insight into inward rectification.
Biophys. Chem.,
2015
Jul
, 202 (40-57).
24
Wu ZJ
et al.
Characterization of a Chinese KCNQ1 mutation (R259H) that shortens repolarization and causes short QT syndrome 2.
J Geriatr Cardiol,
2015
Jul
, 12 (394-401).
25
Cordeiro JM
et al.
Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.
J. Mol. Cell. Cardiol.,
2015
Jul
, 84 (52-60).
26
Chong E
et al.
Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Heart Rhythm,
2015
Jan
30
, ().
27
Sacco S
et al.
The inward rectifier potassium channel Kir2.1 is required for osteoblastogenesis.
Hum. Mol. Genet.,
2015
Jan
15
, 24 (471-9).
28
Masotti A
et al.
Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel encoded by KCNJ6.
Am. J. Hum. Genet.,
2015
Feb
5
, 96 (295-300).
29
Qi XY
et al.
Fibroblast inward-rectifier potassium current upregulation in profibrillatory atrial remodeling.
Circ. Res.,
2015
Feb
27
, 116 (836-45).
30
Riz M
et al.
Inwardly rectifying Kir2.1 currents in human β-cells control electrical activity: Characterisation and mathematical modelling.
Biochem. Biophys. Res. Commun.,
2015
Feb
26
, ().
31
Amaral AC
et al.
Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex.
Neuroscience,
2015
Feb
12
, 286 (79-86).
32
Masia R
et al.
The inward rectifier potassium channel Kir2.1 is expressed in mouse neutrophils from bone marrow and liver.
Am. J. Physiol., Cell Physiol.,
2015
Feb
1
, 308 (C264-76).
33
Gasparoli L
et al.
New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Mol. Pharmacol.,
2015
Feb
, 87 (183-96).
34
Kostera-Pruszczyk A
et al.
Andersen-Tawil syndrome: report of 3 novel mutations and high risk of symptomatic cardiac involvement.
Muscle Nerve,
2015
Feb
, 51 (192-6).
35
Obergrussberger A
et al.
Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module.
J Lab Autom,
2015
Dec
23
, ().
36
Li WP
et al.
[Function and expression of inwardly rectifying potassium channel Kir2.1].
Sheng Li Ke Xue Jin Zhan,
2015
Aug
, 46 (287-9).
37
Huang CW
et al.
Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.
Pflugers Arch.,
2015
Aug
, 467 (1733-46).
38
Huang Y
et al.
[Combined transgenic inhibition of CaMKII and Ik1 on cardiac remodeling].
Sheng Li Xue Bao,
2015
Apr
25
, 67 (201-6).
39
Willis BC
et al.
Protein Assemblies of Sodium and Inward Rectifier Potassium Channels Control Cardiac Excitability and Arrhythmogenesis.
Am. J. Physiol. Heart Circ. Physiol.,
2015
Apr
10
, (ajpheart.00176.2015).
40
Lee JY
et al.
The role of K⁺ conductances in regulating membrane excitability in human gastric corpus smooth muscle.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2015
Apr
1
, 308 (G625-33).
41
Cannon SC
Channelopathies of skeletal muscle excitability.
Compr Physiol,
2015
Apr
, 5 (761-90).
42
Okada M
et al.
A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain.
Biochim. Biophys. Acta,
2015
Apr
, 1850 (657-66).
43
Ahmed M
et al.
Down-regulation of inwardly rectifying Kir2.1 K+ channels by human parvovirus B19 capsid protein VP1.
J. Membr. Biol.,
2015
Apr
, 248 (223-9).
44
Subramanian M
et al.
Idiopathic generalized epilepsy and hypokalemic periodic paralysis in a family of South Indian descent.
Case Rep Neurol Med,
2015
, 2015 (906049).
45
46
Montalbano A
et al.
Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
PLoS ONE,
2015
, 10 (e0140369).
47
48
Ortega A
et al.
Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction.
PLoS ONE,
2015
, 10 (e0145518).
49
Chang HK
et al.
Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels.
Sci Rep,
2015
, 5 (18404).
50
Kamikawa A
et al.
Decrease in an Inwardly Rectifying Potassium Conductance in Mouse Mammary Secretory Cells after Forced Weaning.
PLoS ONE,
2015
, 10 (e0141131).
51
Okada M
et al.
Increase in the titer of lentiviral vectors expressing potassium channels by current blockade during viral vector production.
BMC Neurosci,
2015
, 16 (30).
52
Yang Y
et al.
Diverse Kir expression contributes to distinct bimodal distribution of resting potentials and vasotone responses of arterioles.
PLoS ONE,
2015
, 10 (e0125266).
53
Wu CL
et al.
A single pair of neurons modulates egg-laying decisions in Drosophila.
PLoS ONE,
2015
, 10 (e0121335).
54
Zhang YY
et al.
Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
PLoS ONE,
2015
, 10 (e0138581).
55
Meijer van Putten RM
et al.
Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.
Front Physiol,
2015
, 6 (7).
56
Saito Y
et al.
Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.
PLoS ONE,
2015
, 10 (e0138193).
57
Allegue C
et al.
Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.
PLoS ONE,
2015
, 10 (e0133037).
58
Yang Z
et al.
Effect of adenosine and adenosine receptor antagonist on Müller cell potassium channel in Rat chronic ocular hypertension models.
Sci Rep,
2015
, 5 (11294).
59
Li J
et al.
Identification of the Conformational transition pathway in PIP2 Opening Kir Channels.
Sci Rep,
2015
, 5 (11289).
60
Charolidi N
et al.
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
PLoS ONE,
2015
, 10 (e0128463).
61
Li X
et al.
The clinical and genetic features in a cohort of mainland Chinese patients with thyrotoxic periodic paralysis.
BMC Neurol,
2015
, 15 (38).
62
Wang Y
et al.
The Beneficial Effects of Electro-acupuncture at PC6 (Neiguan-point) of Gene and Protein Expressions of Classical Inward-rectifier Potassium Channels in Myocardial Ischemic Rats.
Acupunct Electrother Res,
2015
, 40 (335-53).
63
Márquez MF
et al.
[Andersen-Tawil syndrome: a review of its clinical and genetic diagnosis with emphasis on cardiac manifestations].
Arch Cardiol Mex,
2014 Oct-Dec
, 84 (278-85).
64
Kanbara T
et al.
Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model.
Neurosci. Lett.,
2014
Sep
19
, 580 (119-24).
65
Kupferman JV
et al.
Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.
Cell,
2014
Sep
11
, 158 (1335-47).
66
Rosenhouse-Dantsker A
et al.
Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2.
Comput Struct Biotechnol J,
2014
Sep
, 11 (131-7).
67
Houtman MJ
et al.
Insights in KIR2.1 channel structure and function by an evolutionary approach; cloning and functional characterization of the first reptilian inward rectifier channel KIR2.1, derived from the California kingsnake (Lampropeltis getula californiae).
Biochem. Biophys. Res. Commun.,
2014
Oct
3
, 452 (992-7).
68
Singhal R
et al.
Colchicine suppresses atrial fibrillation in failing heart.
Int. J. Cardiol.,
2014
Oct
20
, 176 (651-60).
69
Shi D
et al.
Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias.
J. Cell. Mol. Med.,
2014
Oct
, 18 (1992-9).
70
Gómez R
et al.
Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.
Cardiovasc. Res.,
2014
Nov
1
, 104 (337-46).
71
Wen W
et al.
Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas.
Bioorg. Med. Chem. Lett.,
2014
Nov
1
, 24 (5102-6).
72
Shen N
et al.
Barium chloride impaired Kir2.1 inward rectification in its stably transfected HEK 293 cell lines.
Eur. J. Pharmacol.,
2014
May
5
, 730 (164-70).
73
Longden TA
et al.
Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function.
Proc. Natl. Acad. Sci. U.S.A.,
2014
May
20
, 111 (7462-7).
74
Kalscheur MM
et al.
KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia.
Heart Rhythm,
2014
May
, 11 (885-94).
75
Wang X
et al.
The predisposition to thyrotoxic periodic paralysis (TPP) is due to a genetic variant in the inward-rectifying potassium channel, KCNJ2.
Clin. Endocrinol. (Oxf),
2014
May
, 80 (770-1).
76
Zhang YY
et al.
Characterization of functional ion channels in human cardiac c-kit+ progenitor cells.
Basic Res. Cardiol.,
2014
May
, 109 (407).
77
78
Kokunai Y
et al.
A Kir3.4 mutation causes Andersen-Tawil syndrome by an inhibitory effect on Kir2.1.
Neurology,
2014
Mar
25
, 82 (1058-64).
79
Huang CW
et al.
Gating of the Kir2.1 Channel at the Bundle Crossing Region by Intracellular Spermine and Other Cations.
J. Cell. Physiol.,
2014
Mar
14
, ().
80
Raphemot R
et al.
Direct activation of β-cell KATP channels with a novel xanthine derivative.
Mol. Pharmacol.,
2014
Jun
, 85 (858-65).
81
Wydeven N
et al.
Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.
Proc. Natl. Acad. Sci. U.S.A.,
2014
Jul
22
, 111 (10755-60).
82
Hassinen M
et al.
Seasonal acclimatization of the cardiac action potential in the Arctic navaga cod (Eleginus navaga, Gadidae).
J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol.,
2014
Jan
7
, ().
83
Qu YH
et al.
Remodeling of ion channel expression may contribute to electrophysiological consequences caused by methamphetamine in vitro and in vivo.
Biochem. Biophys. Res. Commun.,
2014
Jan
10
, 443 (441-6).
84
Liang B
et al.
G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization.
Cardiovasc. Res.,
2014
Jan
1
, 101 (175-84).
85
Chung MK
et al.
Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.
Eur J Pain,
2014
Jan
, 18 (29-38).
86
Geraldes V
et al.
Chronic depression of hypothalamic paraventricular neuronal activity produces sustained hypotension in hypertensive rats.
Exp. Physiol.,
2014
Jan
, 99 (89-100).
87
Mints Y
et al.
Single nucleotide polymorphisms in proximity to K-channel genes are associated with decreased longitudinal QTc variance.
Ann Noninvasive Electrocardiol,
2014
Jan
, 19 (63-9).
88
Kolb AR
et al.
ESCRT regulates surface expression of the Kir2.1 potassium channel.
Mol. Biol. Cell,
2014
Jan
, 25 (276-89).
89
Sheng J
et al.
Electrophysiology of human cardiac atrial and ventricular telocytes.
J. Cell. Mol. Med.,
2014
Feb
, 18 (355-62).
90
Huang CW
et al.
The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.
Pflugers Arch.,
2014
Feb
, 466 (275-93).
91
Marquis-Nicholson R
et al.
Array comparative genomic hybridization identifies a heterozygous deletion of the entire KCNJ2 gene as a cause of sudden cardiac death.
Circ Cardiovasc Genet,
2014
Feb
, 7 (17-22).
92
Fürst O
et al.
Identification of a cholesterol-binding pocket in inward rectifier K(+) (Kir) channels.
Biophys. J.,
2014
Dec
16
, 107 (2786-96).
93
Kahanovitch U
et al.
Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.
J. Physiol. (Lond.),
2014
Dec
15
, 592 (5373-90).
94
Geraldes V
et al.
Essential role of RVL medullary neuronal activity in the long term maintenance of hypertension in conscious SHR.
Auton Neurosci,
2014
Dec
, 186 (22-31).
95
Lefter S
et al.
Andersen-Tawil syndrome with early fixed myopathy.
J Clin Neuromuscul Dis,
2014
Dec
, 16 (79-82).
96
Xynogalos P
et al.
Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.
Naunyn Schmiedebergs Arch. Pharmacol.,
2014
Dec
, 387 (1153-61).
97
Kukla P
et al.
Electrocardiogram in Andersen-Tawil syndrome. New electrocardiographic criteria for diagnosis of type-1 Andersen-Tawil syndrome.
Curr Cardiol Rev,
2014
Aug
, 10 (222-8).
98
Rinné S
et al.
A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels.
Pflugers Arch.,
2014
Aug
, 466 (1559-70).
99
Díaz-Manera J
et al.
Severe exacerbation of Andersen-Tawil syndrome secondary to thyrotoxicosis.
J. Hum. Genet.,
2014
Aug
, 59 (465-6).
100
Weeke P
et al.
Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.
J. Am. Coll. Cardiol.,
2014
Apr
15
, 63 (1430-7).
101
Farhy Tselnicker I
et al.
Dual regulation of G proteins and the G-protein-activated K+ channels by lithium.
Proc. Natl. Acad. Sci. U.S.A.,
2014
Apr
1
, 111 (5018-23).
102
Iyer V
et al.
Modeling Tissue- and Mutation- Specific Electrophysiological Effects in the Long QT Syndrome: Role of the Purkinje Fiber.
PLoS ONE,
2014
, 9 (e97720).
103
Sivagangabalan G
et al.
Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PLoS ONE,
2014
, 9 (e82179).
104
Munoz C
et al.
Up-regulation of Kir2.1 (KCNJ2) by the serum & glucocorticoid inducible SGK3.
Cell. Physiol. Biochem.,
2014
, 33 (491-500).
105
Yu CC
et al.
Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents.
PLoS ONE,
2014
, 9 (e96691).
106
Kito H
et al.
Membrane hyperpolarization induced by endoplasmic reticulum stress facilitates ca(2+) influx to regulate cell cycle progression in brain capillary endothelial cells.
J. Pharmacol. Sci.,
2014
, 125 (227-32).
107
108
Kumar M
et al.
Focus on Kir7.1: physiology and channelopathy.
Channels (Austin),
2014
, 8 (488-95).
109
Burridge PW
et al.
Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.
Am J Transl Res,
2014
, 6 (724-35).
110
Liang S
et al.
Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes.
Nat Commun,
2014
, 5 (4676).
111
Rosenhouse-Dantsker A
et al.
Identification of novel cholesterol-binding regions in Kir2 channels.
J. Biol. Chem.,
2013
Sep
9
, ().
112
Duan X
Ion Channels, Channelopathies, and Tooth Formation.
J. Dent. Res.,
2013
Sep
27
, ().
113
Ramos-Hunter SJ
et al.
Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators.
Bioorg. Med. Chem. Lett.,
2013
Sep
15
, 23 (5195-8).
114
Cordeiro JM
et al.
Developmental changes in expression and biophysics of ion channels in the canine ventricle.
J. Mol. Cell. Cardiol.,
2013
Sep
10
, 64C (79-89).
115
Fernlund E
et al.
Novel mutation in the KCNJ2 gene is associated with a malignant arrhythmic phenotype of Andersen-Tawil syndrome.
Ann Noninvasive Electrocardiol,
2013
Sep
, 18 (471-8).
116
Zhang L
et al.
Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes.
Sci China Life Sci,
2013
Sep
, 56 (788-96).
117
Olesen MS
et al.
Very early onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation.
Heart Rhythm,
2013
Oct
18
, ().
118
Kang JY
et al.
In vivo expression of a light-activatable potassium channel using unnatural amino acids.
Neuron,
2013
Oct
16
, 80 (358-70).
119
Hasegawa K
et al.
A Novel KCNQ1 Missense Mutation Identified in a Patient with Juvenile-Onset Atrial Fibrillation Causes Constitutively Open IKs Channels.
Heart Rhythm,
2013
Oct
1
, ().
120
Gunnarsson TP
et al.
Effect of intensified training on muscle ion kinetics, fatigue development, and repeated short-term performance in endurance-trained cyclists.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2013
Oct
, 305 (R811-R821).
121
Muessel MJ
et al.
SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology.
Glia,
2013
Oct
, 61 (1620-8).
122
Lee YS
et al.
Long QT syndrome: a Korean single center study.
J. Korean Med. Sci.,
2013
Oct
, 28 (1454-60).
123
Eleawa SM
et al.
Effect of testosterone replacement therapy on cardiac performance and oxidative stress in orchidectomized rats.
Acta Physiol (Oxf),
2013
Oct
, 209 (136-47).
124
Wu XN
et al.
Sucrose-induced receptor kinase SIRK1 regulates a plasma membrane aquaporin in Arabidopsis.
Mol. Cell Proteomics,
2013
Oct
, 12 (2856-73).
125
Jabbari J
et al.
New exome data question the pathogenicity of genetic variants previously associated with catecholaminergic polymorphic ventricular tachycardia.
Circ Cardiovasc Genet,
2013
Oct
, 6 (481-9).
126
Mishra B
et al.
Sodium and potassium currents influence Wallerian degeneration of injured Drosophila axons.
J. Neurosci.,
2013
Nov
27
, 33 (18728-39).
127
Kamikawa A
et al.
Functional expression of a Kir2.1-like inwardly rectifying potassium channel in mouse mammary secretory cells.
Am. J. Physiol., Cell Physiol.,
2013
Nov
20
, ().
128
Waters CW
et al.
Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction.
Proc. Natl. Acad. Sci. U.S.A.,
2013
May
28
, 110 (9160-5).
129
Luo X
et al.
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.
J. Clin. Invest.,
2013
May
1
, 123 (1939-51).
130
Deo M
et al.
KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia.
Proc. Natl. Acad. Sci. U.S.A.,
2013
Mar
12
, 110 (4291-6).
131
Munoz C
et al.
Up-regulation of the inwardly rectifying K⁺ channel Kir2.1 (KCNJ2) by protein kinase B (PKB/Akt) and PIKfyve.
J. Membr. Biol.,
2013
Mar
, 246 (189-97).
132
Saenz del Burgo L
et al.
Chronic effects of corticosterone on GIRK1-3 subunits and 5-HT1A receptor expression in rat brain and their reversal by concurrent fluoxetine treatment.
Eur Neuropsychopharmacol,
2013
Mar
, 23 (229-39).
133
D'Avanzo N
et al.
Energetics and location of phosphoinositide binding in human Kir2.1 channels.
J. Biol. Chem.,
2013
Jun
7
, 288 (16726-37).
134
Rosenhouse-Dantsker A
et al.
Cholesterol sensitivity of KIR2.1 depends on Functional inter-links between the N and C termini.
Channels (Austin),
2013
Jun
27
, 7 ().
135
Vaidyanathan R
et al.
The Interaction of Caveolin 3 Protein with the Potassium Inward Rectifier Channel Kir2.1: PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9).
J. Biol. Chem.,
2013
Jun
14
, 288 (17472-80).
136
Bates EA
A potential molecular target for morphological defects of fetal alcohol syndrome: Kir2.1.
Curr. Opin. Genet. Dev.,
2013
Jun
, 23 (324-9).
137
Jost N
et al.
Ionic mechanisms limiting cardiac repolarization-reserve in humans compared to dogs.
J. Physiol. (Lond.),
2013
Jul
22
, ().
138
Kiss T
et al.
Identification of diterpene alkaloids from Aconitum napellus subsp. firmum and GIRK channel activities of some Aconitum alkaloids.
Fitoterapia,
2013
Jul
19
, ().
139
Amorós I
et al.
Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore.
Biochem. Pharmacol.,
2013
Jul
15
, 86 (267-78).
140
Okada M
et al.
The degradation of the inwardly rectifying potassium channel, Kir2.1, depends on the expression level: Examination with fluorescent proteins.
Brain Res.,
2013
Jul
11
, ().
141
Takanari H
et al.
Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue.
Cardiovasc. Res.,
2013
Jul
1
, 99 (203-14).
142
Lieve KV
et al.
Results of genetic testing in 855 consecutive unrelated patients referred for long QT syndrome in a clinical laboratory.
Genet Test Mol Biomarkers,
2013
Jul
, 17 (553-61).
143
Lai PF
et al.
Mesenchymal stem cell transplantation mitigates electrophysiological remodeling in a rat model of myocardial infarction.
J. Cardiovasc. Electrophysiol.,
2013
Jul
, 24 (813-21).
144
Nam TS
et al.
An algorithm for candidate sequencing in non-dystrophic skeletal muscle channelopathies.
J. Neurol.,
2013
Jul
, 260 (1770-7).
145
Ford J
et al.
Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial Selective Kv1.5/IKur Inhibitor.
J. Cardiovasc. Pharmacol.,
2013
Jan
29
, ().
146
Liu L
et al.
A novel mutation in the transmembrane nonpore region of the KCNH2 gene causes severe clinical manifestations of long QT syndrome.
Heart Rhythm,
2013
Jan
, 10 (61-7).
147
Hilder TA
et al.
Conduction and block of inward rectifier K+ channels: predicted structure of a potent blocker of Kir2.1.
Biochemistry,
2013
Feb
5
, 52 (967-74).
148
Yamamoto Y
et al.
Amiodarone inhibits tissue factor expression in monocytic THP-1 cells.
Eur. J. Pharmacol.,
2013
Feb
15
, 701 (14-9).
149
Liao SY
et al.
Overexpression of Kir2.1 channel in embryonic stem cell-derived cardiomyocytes attenuates posttransplantation proarrhythmic risk in myocardial infarction.
Heart Rhythm,
2013
Feb
, 10 (273-82).
150
Lieu DK
et al.
Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes.
Circ Arrhythm Electrophysiol,
2013
Feb
, 6 (191-201).
151
Chang HK
et al.
Voltage-dependent inhibition of outward Kir2.1 currents by extracellular spermine.
Biochim. Biophys. Acta,
2013
Feb
, 1828 (765-75).
152
Nguyen HL
et al.
Andersen-Tawil syndrome: clinical and molecular aspects.
Int. J. Cardiol.,
2013
Dec
5
, 170 (1-16).
153
Uesugi M
et al.
Low-density plating is sufficient to induce cardiac hypertrophy and electrical remodeling in highly purified human iPS cell-derived cardiomyocytes.
J Pharmacol Toxicol Methods,
2013
Dec
1
, ().
154
Bruehl S
et al.
Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.
Pain,
2013
Dec
, 154 (2853-9).
155
Delannoy E
et al.
Cardiac characteristics and long-term outcome in Andersen-Tawil syndrome patients related to KCNJ2 mutation.
Europace,
2013
Dec
, 15 (1805-11).
156
Kato K
et al.
Cardiac Channelopathies Associated with Infantile Fatal Ventricular Arrhythmias: From the Cradle to the Bench.
J. Cardiovasc. Electrophysiol.,
2013
Aug
26
, ().
157
Wen W
et al.
Discovery of 'molecular switches' within a GIRK activator scaffold that afford selective GIRK inhibitors.
Bioorg. Med. Chem. Lett.,
2013
Aug
15
, 23 (4562-6).
158
Mahajan R
et al.
A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.
Sci Signal,
2013
Aug
13
, 6 (ra69).
159
Tsai WC
et al.
Ablation of the androgen receptor gene modulates atrial electrophysiology and arrhythmogenesis with calcium protein dysregulation.
Endocrinology,
2013
Aug
, 154 (2833-42).
160
Huang W
et al.
Antiarrhythmic effects and ionic mechanisms of allicin on myocardial injury of diabetic rats induced by streptozotocin.
Naunyn Schmiedebergs Arch. Pharmacol.,
2013
Aug
, 386 (697-704).
161
Szuts V
et al.
Altered expression of genes for Kir ion channels in dilated cardiomyopathy.
Can. J. Physiol. Pharmacol.,
2013
Aug
, 91 (648-56).
162
Salem KA
et al.
Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats.
Mol. Cell. Biochem.,
2013
Aug
, 380 (83-96).
163
Horga A
et al.
Prevalence study of genetically defined skeletal muscle channelopathies in England.
Neurology,
2013
Apr
16
, 80 (1472-5).
164
Boulis NM
et al.
Regulated neuronal neuromodulation via spinal cord expression of the gene for the inwardly rectifying potassium channel 2.1 (Kir2.1).
Neurosurgery,
2013
Apr
, 72 (653-61; discussion 661).
165
Treiber F
et al.
Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.
Biochim. Biophys. Acta,
2013
Apr
, 1828 (1214-21).
166
Zhang Y
et al.
Downregulation of miR-151-5p contributes to increased susceptibility to arrhythmogenesis during myocardial infarction with estrogen deprivation.
PLoS ONE,
2013
, 8 (e72985).
167
Bernstein JD
et al.
Potential use of potassium efflux-deficient yeast for studying trafficking signals and potassium channel functions.
FEBS Open Bio,
2013
, 3 (196-203).
168
Fujii M
et al.
New screening system for selective blockers of voltage-gated K(+) channels using recombinant cell lines dying upon single action potential.
J. Pharmacol. Sci.,
2013
, 123 (147-58).
169
Hsiao PY
et al.
Gene mutations in cardiac arrhythmias: a review of recent evidence in ion channelopathies.
Appl Clin Genet,
2013
, 6 (1-13).
170
Murthy R
et al.
Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1.
Mol Brain,
2013
, 6 (30).
171
Tsai KL
et al.
The inhibition of inwardly rectifying K+ channels by memantine in macrophages and microglial cells.
Cell. Physiol. Biochem.,
2013
, 31 (938-51).
172
Atkinson AJ
et al.
Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.
J Am Heart Assoc,
2013
, 2 (e000246).
173
Limberg MM
et al.
Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype.
Basic Res. Cardiol.,
2013
, 108 (353).
174
175
Lee SJ
et al.
Secondary anionic phospholipid binding site and gating mechanism in Kir2.1 inward rectifier channels.
Nat Commun,
2013
, 4 (2786).
176
Leroy MC
et al.
Epidermal growth factor receptor down-regulation triggers human myoblast differentiation.
PLoS ONE,
2013
, 8 (e71770).
177
Kawamura M
et al.
Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan.
Circ. J.,
2013
, 77 (1705-13).
178
Pérez Riera AR
et al.
Congenital short QT syndrome: landmarks of the newest arrhythmogenic cardiac channelopathy.
Cardiol J,
2013
, 20 (464-71).
179
Jonchere VV
et al.
Identification of uterine ion transporters for mineralisation precursors of the avian eggshell.
BMC Physiol.,
2012
Sep
4
, 12 (10).
180
Kuramoto Y
et al.
Andersen-Tawil syndrome associated with aborted sudden cardiac death: atrial pacing was effective for ventricular arrhythmias.
Am. J. Med. Sci.,
2012
Sep
, 344 (248-50).
181
Kim S
et al.
Paradoxical contribution of SK3 and GIRK channels to the activation of mouse vomeronasal organ.
Nat. Neurosci.,
2012
Sep
, 15 (1236-44).
182
Cheung CL
et al.
Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3.
Nat. Genet.,
2012
Sep
, 44 (1026-9).
183
Chu W
et al.
Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome.
Cardiovasc. Res.,
2012
Oct
1
, 96 (90-8).
184
Dahal GR
et al.
An inwardly rectifying K+ channel is required for patterning.
Development,
2012
Oct
, 139 (3653-64).
185
Rosenhouse-Dantsker A
et al.
Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).
J. Biol. Chem.,
2012
Nov
23
, 287 (40266-78).
186
Goldoni D
et al.
A novel dual-fluorescence strategy for functionally validating microRNA targets in 3' untranslated regions: regulation of the inward rectifier potassium channel K(ir)2.1 by miR-212.
Biochem. J.,
2012
Nov
15
, 448 (103-13).
187
Kirkton RD
et al.
Genetic engineering of somatic cells to study and improve cardiac function.
Europace,
2012
Nov
, 14 Suppl 5 (v40-v49).
188
Yang L
et al.
Interactions of external K+ and internal blockers in a weak inward-rectifier K+ channel.
J. Gen. Physiol.,
2012
Nov
, 140 (529-40).
189
Jongjaroenprasert W
et al.
A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
J. Hum. Genet.,
2012
May
, 57 (301-4).
190
Kloukina V
et al.
G-protein-gated inwardly rectifying K+ channel 4 (GIRK4) immunoreactivity in chemically defined neurons of the hypothalamic arcuate nucleus that control body weight.
J. Chem. Neuroanat.,
2012
May
, 44 (14-23).
191
Casini S
et al.
Decreased inward rectification of Kir2.1 channels is a novel mechanism underlying the short QT syndrome.
Cardiovasc. Res.,
2012
Mar
15
, 93 (535-6).
192
193
Yamada K
et al.
Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population.
Hum. Genet.,
2012
Mar
, 131 (443-51).
194
Troncoso Brindeiro CM
et al.
Tempol prevents altered K(+) channel regulation of afferent arteriolar tone in diabetic rat kidney.
Hypertension,
2012
Mar
, 59 (657-64).
195
Liu TA
et al.
Revisiting inward rectification: K ions permeate through Kir2.1 channels during high-affinity block by spermidine.
J. Gen. Physiol.,
2012
Mar
, 139 (245-59).
196
Sitaraman D
et al.
Serotonin is critical for rewarded olfactory short-term memory in Drosophila.
J. Neurogenet.,
2012
Jun
, 26 (238-44).
197
Gönczi M
et al.
Age-dependent changes in ion channel mRNA expression in canine cardiac tissues.
Gen. Physiol. Biophys.,
2012
Jun
, 31 (153-62).
198
Kimura H
et al.
Phenotype variability in patients carrying KCNJ2 mutations.
Circ Cardiovasc Genet,
2012
Jun
, 5 (344-53).
199
Milstein ML
et al.
Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia.
Proc. Natl. Acad. Sci. U.S.A.,
2012
Jul
31
, 109 (E2134-43).
200
Kulzer M
et al.
Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A.
Biochem. Biophys. Res. Commun.,
2012
Jul
27
, 424 (315-20).
201
Fujii M
et al.
Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates.
J Biomol Screen,
2012
Jul
, 17 (773-84).
202
Wei F
et al.
Mesenchymal stem cells neither fully acquire the electrophysiological properties of mature cardiomyocytes nor promote ventricular arrhythmias in infarcted rats.
Basic Res. Cardiol.,
2012
Jul
, 107 (274).
203
Marjamaa A
et al.
A common variant near the KCNJ2 gene is associated with T-peak to T-end interval.
Heart Rhythm,
2012
Jul
, 9 (1099-103).
204
Hocking JC
et al.
Neural activity and branching of embryonic retinal ganglion cell dendrites.
Mech. Dev.,
2012
Jul
, 129 (125-35).
205
Feng M
et al.
Activation of epidermal growth factor receptor mediates reperfusion arrhythmias in anaesthetized rats.
Cardiovasc. Res.,
2012
Jan
1
, 93 (60-8).
206
Puppala D
et al.
Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue.
Toxicol. Sci.,
2012
Jan
, 131 (292-301).
207
Luo HY
et al.
[Expression of Kir2.1, SCN5a and SCN1b channel genes in mouse cardiomyocytes with various electric properties: patch clamp combined with single cell RT-PCR study].
Sheng Li Xue Bao,
2012
Feb
25
, 64 (82-6).
208
209
Cazorla M
et al.
Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels.
J. Neurosci.,
2012
Feb
15
, 32 (2398-409).
210
Jonsson MK
et al.
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.
,
2012
Feb
14
, ().
211
Seebohm G
et al.
Altered stress stimulation of inward rectifier potassium channels in Andersen-Tawil syndrome.
FASEB J.,
2012
Feb
, 26 (513-22).
212
Hu B
et al.
Experimental study on inhibition of rat ventricular Ik1 by RNA interference targeting the KCNJ2 gene.
Biosci Trends,
2012
Feb
, 6 (26-32).
213
Wydeven N
et al.
Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity.
Proc. Natl. Acad. Sci. U.S.A.,
2012
Dec
26
, 109 (21492-7).
214
Chu PY
et al.
Genetic variant rs623011 (17q24.3) associates with non-familial thyrotoxic and sporadic hypokalemic paralysis.
Clin. Chim. Acta,
2012
Dec
24
, 414 (105-8).
215
Tajada S
et al.
High blood pressure associates with the remodelling of inward rectifier K+ channels in mice mesenteric vascular smooth muscle cells.
J. Physiol. (Lond.),
2012
Dec
1
, 590 (6075-91).
216
Song YW
et al.
Normokalemic periodic paralysis is not a distinct disease.
Muscle Nerve,
2012
Dec
, 46 (914-6).
217
Robertson JL
et al.
Multi-ion distributions in the cytoplasmic domain of inward rectifier potassium channels.
Biophys. J.,
2012
Aug
8
, 103 (434-43).
218
McSpadden LC
et al.
Size and ionic currents of unexcitable cells coupled to cardiomyocytes distinctly modulate cardiac action potential shape and pacemaking activity in micropatterned cell pairs.
Circ Arrhythm Electrophysiol,
2012
Aug
1
, 5 (821-30).
219
Cingolani E
et al.
Biological pacemaker created by percutaneous gene delivery via venous catheters in a porcine model of complete heart block.
Heart Rhythm,
2012
Aug
, 9 (1310-8).
220
Tan SV
et al.
Membrane dysfunction in Andersen-Tawil syndrome assessed by velocity recovery cycles.
Muscle Nerve,
2012
Aug
, 46 (193-203).
221
Chinushi M
et al.
Exercise-related QT interval shortening with a peaked T wave in a healthy boy with a family history of sudden cardiac death.
Pacing Clin Electrophysiol,
2012
Aug
, 35 (e239-42).
222
Lei X
et al.
[Diclofenac inhibits Kv1.3 and Kir2.1 expressions in human macrophages and affects the membrane potential and foam cell formation].
Nan Fang Yi Ke Da Xue Xue Bao,
2012
Aug
, 32 (1067-73).
223
224
Levin ME
et al.
The Function and Molecular Identity of Inward Rectifier Channels in Vestibular Hair Cells of the Mouse Inner Ear.
,
2012
Apr
11
, ().
225
Adeniran I
et al.
Proarrhythmia in KCNJ2-linked short QT syndrome: insights from modelling.
Cardiovasc. Res.,
2012
Apr
1
, 94 (66-76).
226
Wu J
et al.
Regulatory mechanisms underlying the modulation of GIRK1/GIRK4 heteromeric channels by P2Y receptors.
Pflugers Arch.,
2012
Apr
, 463 (625-33).
227
Wang CL
et al.
Evidence for Mitoxantrone-induced Block of Inwardly Rectifying K Channels Expressed in the Osteoclast Precursor RAW 264.7 Cells Differentiated with Lipopolysaccharide.
Cell. Physiol. Biochem.,
2012
, 30 (687-701).
228
Houtman MJ
et al.
Experimental Mapping of the Canine KCNJ2 and KCNJ12 Gene Structures and Functional Analysis of the Canine K(IR)2.2 ion Channel.
Front Physiol,
2012
, 3 (9).
229
Hancock DB
et al.
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
PLoS Genet.,
2012
, 8 (e1003098).
230
Xu XH
et al.
Allitridi inhibits multiple cardiac potassium channels expressed in HEK 293 cells.
PLoS ONE,
2012
, 7 (e51550).
231
Sadaf S
et al.
Synaptic activity in serotonergic neurons is required for air-puff stimulated flight in Drosophila melanogaster.
PLoS ONE,
2012
, 7 (e46405).
232
Lü Q
et al.
Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.
Mol Med Report,
2011 Sep-Oct
, 4 (941-5).
233
Berlin S
et al.
Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits.
J. Biol. Chem.,
2011
Sep
23
, 286 (33223-35).
234
Loscalzo LM
et al.
Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents.
Pharmacol. Biochem. Behav.,
2011
Sep
, 99 (333-41).
235
Ferrer T
et al.
Carvedilol inhibits Kir2.3 channels by interference with PIP₂-channel interaction.
Eur. J. Pharmacol.,
2011
Oct
1
, 668 (72-7).
236
López-Izquierdo A
et al.
Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.
Pflugers Arch.,
2011
Oct
, 462 (505-17).
237
Burge JA
et al.
Novel Insights into the Pathomechanisms of Skeletal Muscle Channelopathies.
,
2011
Nov
15
, ().
238
Gui YX
et al.
Verification of expressions of Kir2 as potential peripheral biomarkers in lymphocytes from patients with Parkinson's disease.
Neurosci. Lett.,
2011
Nov
14
, 505 (104-8).
239
Thompson JL
et al.
Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations.
J. Physiol. (Lond.),
2011
Nov
1
, 589 (5057-69).
240
Marrus SB
et al.
Characterization of a novel, dominant negative KCNJ2 mutation associated with Andersen-Tawil syndrome.
,
2011
Nov
1
, 5 ().
241
Obeyesekere MN
et al.
KCNJ2 variant of unknown significance reclassified as long QT syndrome causing ventricular fibrillation.
Can J Cardiol,
2011
Nov
, 27 (870.e11-3).
242
Parvez B
et al.
The "missing" link in atrial fibrillation heritability.
J Electrocardiol,
2011
Nov
, 44 (641-4).
243
Kienitz MC
et al.
Remodeling of inward rectifying K(+) currents in rat atrial myocytes by overexpression of A(1)-adenosine receptors.
Basic Res. Cardiol.,
2011
Nov
, 106 (953-66).
244
Piatti VC
et al.
The timing for neuronal maturation in the adult hippocampus is modulated by local network activity.
J. Neurosci.,
2011
May
25
, 31 (7715-28).
245
Alesutan I
et al.
Inhibition of Kir2.1 (KCNJ2) by the AMP-activated protein kinase.
Biochem. Biophys. Res. Commun.,
2011
May
20
, 408 (505-10).
246
247
Dassau L
et al.
Kir2.6 regulates the surface expression of Kir2.x inward rectifier potassium channels.
J. Biol. Chem.,
2011
Mar
18
, 286 (9526-41).
248
Ma D
et al.
Golgi export of the Kir2.1 channel is driven by a trafficking signal located within its tertiary structure.
Cell,
2011
Jun
24
, 145 (1102-15).
249
Sakata S
et al.
Coupling of the phosphatase activity of Ci-VSP to its voltage sensor activity over the entire range of voltage sensitivity.
J. Physiol. (Lond.),
2011
Jun
1
, 589 (2687-705).
250
Liu TA
et al.
Extracellular K+ elevates outward currents through Kir2.1 channels by increasing single-channel conductance.
Biochim. Biophys. Acta,
2011
Jun
, 1808 (1772-8).
251
Wu Y
et al.
GABAB receptor-mediated tonic inhibition of noradrenergic A7 neurons in the rat.
J. Neurophysiol.,
2011
Jun
, 105 (2715-28).
252
Doi T
et al.
A novel KCNJ2 nonsense mutation, S369X, impedes trafficking and causes a limited form of Andersen-Tawil syndrome.
Circ Cardiovasc Genet,
2011
Jun
, 4 (253-60).
253
254
Zhang XH
et al.
Functional ion channels and cell proliferation in 3T3-L1 preadipocytes.
,
2011
Jul
5
, ().
255
Jang SS
et al.
Endothelial progenitor cells functionally express inward rectifier potassium channels.
Am. J. Physiol., Cell Physiol.,
2011
Jul
, 301 (C150-61).
256
Vortherms TA
et al.
Comparative analysis of inactivated-state block of N-type (Ca(v)2.2) calcium channels.
Inflamm. Res.,
2011
Jul
, 60 (683-93).
257
Barc J
et al.
Screening for copy number variation in genes associated with the long QT syndrome: clinical relevance.
J. Am. Coll. Cardiol.,
2011
Jan
4
, 57 (40-7).
258
Bax NA
et al.
Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells.
,
2011
Jan
20
, ().
259
Rosenhouse-Dantsker A
et al.
Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore.
Biophys. J.,
2011
Jan
19
, 100 (381-9).
260
Wang LH
et al.
Berberine elicits anti-arrhythmic effects via IK1/Kir2.1 in the rat type 2 diabetic myocardial infarction model.
Phytother Res,
2011
Jan
, 25 (33-7).
261
Hazra R
et al.
A transcriptomic analysis of type I-III neurons in the bed nucleus of the stria terminalis.
,
2011
Feb
7
, ().
262
Noujaim SF
et al.
Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.
,
2011
Feb
2
, ().
263
Cheng WW
et al.
Dual-mode phospholipid regulation of human inward rectifying potassium channels.
Biophys. J.,
2011
Feb
2
, 100 (620-8).
264
Barajas-Martinez H
et al.
Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry.
Circ Cardiovasc Genet,
2011
Feb
1
, 4 (51-7).
265
Machida T
et al.
Effects of a highly selective acetylcholine-activated K+ channel blocker on experimental atrial fibrillation.
Circ Arrhythm Electrophysiol,
2011
Feb
, 4 (94-102).
266
Marshall GE
et al.
Remodelling of human atrial K(+) currents but not ion channel expression by chronic β-blockade.
,
2011
Dec
8
, ().
267
Hattori T
et al.
A novel gain-of-function KCNJ2 mutation associated with short QT syndrome impairs inward rectification of Kir2.1 currents.
,
2011
Dec
8
, ().
268
Fernandez-Alacid L
et al.
Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain.
Eur. J. Neurosci.,
2011
Dec
, 34 (1724-36).
269
Obara-Michlewska M
et al.
Down-regulation of Kir4.1 in the cerebral cortex of rats with liver failure and in cultured astrocytes treated with glutamine: Implications for astrocytic dysfunction in hepatic encephalopathy.
J. Neurosci. Res.,
2011
Dec
, 89 (2018-27).
270
Cheng CJ
et al.
Identification and functional characterization of Kir2.6 mutations associated with non-familial hypokalemic periodic paralysis.
J. Biol. Chem.,
2011
Aug
5
, 286 (27425-35).
271
Zhang DY
et al.
Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition.
Biochim. Biophys. Acta,
2011
Aug
, 1808 (1993-9).
272
El Gebeily G
et al.
Upregulation of ventricular potassium channels by chronic tamoxifen treatment.
Cardiovasc. Res.,
2011
Apr
1
, 90 (68-76).
273
López-Izquierdo A
et al.
The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.
J. Cardiovasc. Pharmacol.,
2011
Apr
, 57 (407-15).
274
D'Avanzo N
et al.
Enantioselective protein-sterol interactions mediate regulation of both prokaryotic and eukaryotic inward rectifier K+ channels by cholesterol.
PLoS ONE,
2011
, 6 (e19393).
275
White MD
et al.
A Molecular Toolbox for Rapid Generation of Viral Vectors to Up- or Down-Regulate Neuronal Gene Expression in vivo.
Front Mol Neurosci,
2011
, 4 (8).
276
Liu Y
et al.
Overexpression of M₃ muscarinic receptor is a novel strategy for preventing sudden cardiac death in transgenic mice.
Mol. Med.,
2011
, 17 (1179-87).
277
Wen HZ
et al.
Semaphorin 3A attenuates electrical remodeling at infarct border zones in rats after myocardial infarction.
Tohoku J. Exp. Med.,
2011
, 225 (51-7).
278
Modoni A
et al.
Lack of any cardiac involvement in a patient with Andersen-Tawil syndrome associated with the c.574A→G mutation in KCNJ2.
Cardiology,
2011
, 120 (200-3).
279
Kobayashi T
et al.
Inhibition of g protein-activated inwardly rectifying k channels by different classes of antidepressants.
PLoS ONE,
2011
, 6 (e28208).
280
Jabbari J
et al.
Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians.
Cardiology,
2011
, 118 (116-20).
281
Pivonkova H
et al.
Impact of Global Cerebral Ischemia on K(+) Channel Expression and Membrane Properties of Glial Cells in the Rat Hippocampus.
,
2010
Sep
9
, ().
282
Vaidyanathan R
et al.
Regulation of cardiac inward rectifier potassium current (I(K1)) by synapse-associated protein-97.
J. Biol. Chem.,
2010
Sep
3
, 285 (28000-9).
283
Ciruela F
et al.
Evidence for oligomerization between GABA(B) receptors and GIRK channels containing the GIRK1 and GIRK3 subunits.
,
2010
Sep
16
, ().
284
Arora D
et al.
Altered neurotransmission in the mesolimbic reward system of Girk mice.
J. Neurochem.,
2010
Sep
1
, 114 (1487-97).
285
Farhang B
et al.
The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons.
Neuropharmacology,
2010
Sep
, 59 (190-200).
286
D'Avanzo N
et al.
Direct and specific activation Of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate.
,
2010
Oct
4
, ().
287
Voigt N
et al.
Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation.
Circ Arrhythm Electrophysiol,
2010
Oct
1
, 3 (472-80).
288
Sordel T
et al.
The development of high quality seals for silicon patch-clamp chips.
Biomaterials,
2010
Oct
, 31 (7398-410).
289
Panama BK
et al.
Functional consequences of Kir2.1/Kir2.2 subunit heteromerization.
Pflugers Arch.,
2010
Oct
, 460 (839-49).
290
291
Miura H
et al.
Cigarette smoking impairs sodium-potassium ATPase activity in the human coronary microcirculation.
,
2010
Nov
12
, ().
292
Park JH
et al.
High expression of large-conductance Ca(2+)-activated K(+) channel in the CD133(+) subpopulation of SH-SY5Y neuroblastoma cells.
,
2010
May
7
, ().
293
Jonsson MK
et al.
Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.
Stem Cell Res,
2010
May
, 4 (189-200).
294
Kurata HT
et al.
Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1.
J. Gen. Physiol.,
2010
May
, 135 (495-508).
295
Bhave G
et al.
Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities.
Future Med Chem,
2010
May
, 2 (757-74).
296
Beacham DW
et al.
Cell-Based Potassium Ion Channel Screening Using the FluxORTM Assay.
,
2010
Mar
5
, ().
297
Tristani-Firouzi M
et al.
Kir 2.1 channelopathies: the Andersen-Tawil syndrome.
,
2010
Mar
21
, ().
298
Le Menuet D
et al.
Mineralocorticoid Receptor Overexpression in Embryonic Stem Cell Derived Cardiomyocytes Increases Their Beating Frequency.
,
2010
Mar
17
, ().
299
Chan HF
et al.
A novel neuropsychiatric phenotype of KCNJ2 mutation in one Taiwanese family with Andersen-Tawil syndrome.
J. Hum. Genet.,
2010
Mar
, 55 (186-8).
300
Ciurzyński M
et al.
[QTU pattern in a patient with the Anderson-Tawil syndrome]
Kardiol Pol,
2010
Mar
, 68 (339-41; discussion 342).
301
Ruan Q
et al.
Effects of Kir2.1 gene transfection in cochlear hair cells and application of neurotrophic factors on survival and neurite growth of co-cultured cochlear spiral ganglion neurons.
Mol. Cell. Neurosci.,
2010
Mar
, 43 (326-39).
302
Noujaim SF
et al.
Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.
,
2010
Jun
28
, ().
303
Wagner V
et al.
Cloning and characterisation of GIRK1 variants resulting from alternative RNA editing of the KCNJ3 gene transcript in a human breast cancer cell line.
J. Cell. Biochem.,
2010
Jun
1
, 110 (598-608).
304
Kobayashi T
et al.
Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine.
Neuropsychopharmacology,
2010
Jun
, 35 (1560-9).
305
López-Izquierdo A
et al.
Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism.
Eur. J. Pharmacol.,
2010
Jul
25
, 638 (33-41).
306
Chang HK
et al.
The extracellular K+ concentration dependence of outward currents through Kir2.1 channels is regulated by extracellular Na+ and Ca2+.
J. Biol. Chem.,
2010
Jul
23
, 285 (23115-25).
307
Raz-Prag D
et al.
Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration.
Proc. Natl. Acad. Sci. U.S.A.,
2010
Jul
13
, 107 (12710-5).
308
Rosenhouse-Dantsker A
et al.
Comparative analysis of cholesterol sensitivity of Kir channels: Role of the CD loop.
Channels (Austin),
2010
Jan
20
, 4 ().
309
Lin CW
et al.
Genetically increased cell-intrinsic excitability enhances neuronal integration into adult brain circuits.
Neuron,
2010
Jan
14
, 65 (32-9).
311
Berlin S
et al.
G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK).
J. Biol. Chem.,
2010
Feb
26
, 285 (6179-85).
312
Grunnet M
Repolarization of the cardiac action potential. Does an increase in repolarization capacity constitute a new anti-arrhythmic principle?
Acta Physiol (Oxf),
2010
Feb
, 198 Suppl 676 (1-48).
313
Mizuno H
et al.
Pre-synaptic and post-synaptic neuronal activity supports the axon development of callosal projection neurons during different post-natal periods in the mouse cerebral cortex.
Eur. J. Neurosci.,
2010
Feb
, 31 (410-24).
314
Kristensen M
et al.
Potassium-transporting proteins in skeletal muscle: cellular location and fibre-type differences.
Acta Physiol (Oxf),
2010
Feb
, 198 (105-23).
315
Serratrice G
et al.
[Potassium channelopathies and Morvan's syndromes].
Bull. Acad. Natl. Med.,
2010
Feb
, 194 (391-406; discussion 406-7).
316
Matsuda H
et al.
Voltage-dependent block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1, with asymmetrical K+ concentrations.
J. Physiol. (Lond.),
2010
Dec
1
, 588 (4673-81).
317
Walsh KB
A real-time screening assay for GIRK1/4 channel blockers.
J Biomol Screen,
2010
Dec
, 15 (1229-37).
318
Caballero R
et al.
Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification.
Proc. Natl. Acad. Sci. U.S.A.,
2010
Aug
31
, 107 (15631-6).
320
Rajakulendran S
et al.
Muscle weakness, palpitations and a small chin: the Andersen-Tawil syndrome.
Pract Neurol,
2010
Aug
, 10 (227-31).
321
Yamada A
et al.
Role of pre- and postsynaptic activity in thalamocortical axon branching.
Proc. Natl. Acad. Sci. U.S.A.,
2010
Apr
20
, 107 (7562-7).
322
Lee HA
et al.
Electrophysiological Effects of the Anti-Cancer Drug Lapatinib on Cardiac Repolarization.
,
2010
Apr
12
, ().
323
Lim BC
et al.
Andersen cardiodysrhythmic periodic paralysis with KCNJ2 mutations: a novel mutation in the pore selectivity filter residue.
J. Child Neurol.,
2010
Apr
, 25 (490-3).
324
Nof E
et al.
A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death.
Circ Cardiovasc Genet,
2010
Apr
, 3 (199-206).
325
Yoon YJ
et al.
Pharmacological manipulation of GABA-driven activity in ovo disrupts the development of dendritic morphology but not the maturation of spinal cord network activity.
Neural Dev,
2010
, 5 (11).
326
Holmegard HN
et al.
Genetic variation in the inwardly rectifying K channel subunits KCNJ3 (GIRK1) and KCNJ5 (GIRK4) in patients with sinus node dysfunction.
Cardiology,
2010
, 115 (176-81).
327
Liu A
et al.
Functional Characterization of Inward Rectifier Potassium Ion Channel in Murine Fetal Ventricular Cardiomyocytes.
,
2010
, 26 (413-420).
328
Balana B
et al.
Mutagenesis and functional analysis of ion channels heterologously expressed in Mammalian cells.
J Vis Exp,
2010
, ().
329
330
Lee HA
et al.
Cellular mechanism of the QT prolongation induced by sulpiride.
Int. J. Toxicol.,
2009 May-Jun
, 28 (207-12).
331
Osawa M
et al.
Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel.
J. Biol. Chem.,
2009
Sep
18
, 284 (26117-26).
332
Young CC
et al.
Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy.
J. Physiol. (Lond.),
2009
Sep
1
, 587 (4213-33).
333
Chan YC
et al.
Synergistic effects of inward rectifier (I) and pacemaker (I) currents on the induction of bioengineered cardiac automaticity.
J. Cardiovasc. Electrophysiol.,
2009
Sep
, 20 (1048-54).
334
Yoshida T
et al.
Regulation of synaptic vesicle accumulation and axon terminal remodeling during synapse formation by distinct Ca signaling.
J. Neurochem.,
2009
Oct
, 111 (160-70).
335
Sacconi S
et al.
Mechanisms underlying Andersen's syndrome pathology in skeletal muscle are revealed in human myotubes.
Am. J. Physiol., Cell Physiol.,
2009
Oct
, 297 (C876-85).
336
Vega AL
et al.
Protein kinase A-dependent biophysical phenotype for V227F-KCNJ2 mutation in catecholaminergic polymorphic ventricular tachycardia.
Circ Arrhythm Electrophysiol,
2009
Oct
, 2 (540-7).
337
Shan H
et al.
Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.
Br. J. Pharmacol.,
2009
Nov
, 158 (1227-35).
338
Soltysinska E
et al.
Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.
Pflugers Arch.,
2009
Nov
, 459 (11-23).
339
Müllner C
et al.
Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.
FEBS J.,
2009
Nov
, 276 (6218-26).
340
El Harchi A
et al.
Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome.
J. Mol. Cell. Cardiol.,
2009
Nov
, 47 (743-7).
341
Lewis LM
et al.
High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.
Mol. Pharmacol.,
2009
Nov
, 76 (1094-103).
342
Ponce-Balbuena D
et al.
Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
J. Pharmacol. Exp. Ther.,
2009
Nov
, 331 (563-73).
343
Maguy A
et al.
Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure.
Circ. Res.,
2009
May
8
, 104 (1113-22).
344
Schweizer PA
et al.
Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.
Basic Res. Cardiol.,
2009
May
7
, ().
345
Epshtein Y
et al.
Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol.
Proc. Natl. Acad. Sci. U.S.A.,
2009
May
12
, 106 (8055-60).
346
Chen J
et al.
PKA phosphorylation of HERG protein regulates the rate of channel synthesis.
Am. J. Physiol. Heart Circ. Physiol.,
2009
May
, 296 (H1244-54).
347
Ishihara K
et al.
Heteromeric assembly of inward rectifier channel subunit Kir2.1 with Kir3.1 and with Kir3.4.
Biochem. Biophys. Res. Commun.,
2009
Mar
20
, 380 (832-7).
348
Kim Y
et al.
High throughput screening assay of alpha(1G) T-type Ca2+ channels and comparison with patch-clamp studies.
Comb. Chem. High Throughput Screen.,
2009
Mar
, 12 (296-302).
349
Zaks-Makhina E
et al.
Specific and slow inhibition of the kir2.1 K+ channel by gambogic acid.
J. Biol. Chem.,
2009
Jun
5
, 284 (15432-8).
350
Aryal P
et al.
A discrete alcohol pocket involved in GIRK channel activation.
Nat. Neurosci.,
2009
Jun
28
, ().
351
Fernández-Alacid L
et al.
Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.
J. Neurochem.,
2009
Jun
22
, ().
352
Ureche ON
et al.
Differential modulation of cardiac potassium channels by Grb adaptor proteins.
Biochem. Biophys. Res. Commun.,
2009
Jun
19
, 384 (28-31).
353
Yokogawa M
et al.
Backbone resonance assignments for the cytoplasmic regions of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).
Biomol NMR Assign,
2009
Jun
, 3 (125-8).
354
Favero M
et al.
On the mechanism of action of muscle fibre activity in synapse competition and elimination at the mammalian neuromuscular junction.
Eur. J. Neurosci.,
2009
Jun
, 29 (2327-34).
355
Wagner S
et al.
Ca/calmodulin kinase II differentially modulates potassium currents.
Circ Arrhythm Electrophysiol,
2009
Jun
, 2 (285-94).
356
Park HJ
et al.
Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.
Circ. Res.,
2009
Jul
31
, 105 (287-94).
357
Sridhar A
et al.
Chronic heart failure and the substrate for atrial fibrillation.
Cardiovasc. Res.,
2009
Jul
17
, ().
358
Gómez R
et al.
Nitric Oxide Increases Cardiac IK1 by Nitrosylation of Cysteine 76 of Kir2.1 Channels.
Circ. Res.,
2009
Jul
16
, ().
359
Rubinstein M
et al.
Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.
J. Physiol. (Lond.),
2009
Jul
15
, 587 (3473-91).
360
Chung HJ
et al.
Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels.
Proc. Natl. Acad. Sci. U.S.A.,
2009
Jan
13
, 106 (629-34).
361
Loewen ME
et al.
Shared requirement for dynein function and intact microtubule cytoskeleton for normal surface expression of cardiac potassium channels.
Am. J. Physiol. Heart Circ. Physiol.,
2009
Jan
, 296 (H71-83).
362
Sekar RB
et al.
IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers.
Circ. Res.,
2009
Feb
13
, 104 (355-64).
363
Boyer SB
et al.
Regulation of Kir2.1 channels by the Rho-GTPase, Rac1.
J. Cell. Physiol.,
2009
Feb
, 218 (385-93).
364
Kobayashi T
et al.
Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels.
Neuropharmacology,
2009
Feb
, 56 (499-506).
365
Chang HK
et al.
K+ binding in the G-loop and water cavity facilitates Ba2+ movement in the Kir2.1 channel.
Biochim. Biophys. Acta,
2009
Feb
, 1788 (500-6).
366
Félétou M
Calcium-activated potassium channels and endothelial dysfunction: therapeutic options?
Br. J. Pharmacol.,
2009
Feb
, 156 (545-62).
367
Iturralde-Torres P
et al.
[Genetic in long QT syndromes]
Arch Cardiol Mex,
2009
Dec
, 79 Suppl 2 (26-30).
368
Kim JB
et al.
Novel de novo mutation in the KCNJ2 gene in a patient with Andersen-Tawil syndrome.
Pediatr. Neurol.,
2009
Dec
, 41 (464-6).
369
Girmatsion Z
et al.
Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation.
Heart Rhythm,
2009
Dec
, 6 (1802-9).
370
Tai K
et al.
Ion-blocking sites of the Kir2.1 channel revealed by multiscale modeling.
Biochemistry,
2009
Aug
4
, ().
371
Brevet M
et al.
Deregulation of 2 potassium channels in pancreas adenocarcinomas: implication of KV1.3 gene promoter methylation.
Pancreas,
2009
Aug
, 38 (649-54).
372
Zhang DY
et al.
Human Kir2.1 channel carries a transient outward potassium current with inward rectification.
Pflugers Arch.,
2009
Apr
, 457 (1275-85).
373
Pfeufer A
et al.
Common variants at ten loci modulate the QT interval duration in the QTSCD Study.
Nat. Genet.,
2009
Apr
, 41 (407-14).
374
Chatelain FC
et al.
Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block.
PLoS ONE,
2009
, 4 (e7496).
375
Hong CM
et al.
Effects of autoantibodies against M2 muscarinic acetylcholine receptors on rabbit atria in vivo.
Cardiology,
2009
, 112 (180-7).
376
Kobayashi T
et al.
Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3.
PLoS ONE,
2009
, 4 (e6311).
377
Hodge JJ
Ion channels to inactivate neurons in Drosophila.
Front Mol Neurosci,
2009
, 2 (13).
378
Li GR
et al.
Characterization of multiple ion channels in cultured human cardiac fibroblasts.
PLoS ONE,
2009
, 4 (e7307).
379
López-Izquierdo A
et al.
Chloroquine blocks a mutant Kir2.1 channel responsible for short QT syndrome and normalizes repolarization properties in silico.
Cell. Physiol. Biochem.,
2009
, 24 (153-60).
380
Moussaud S
et al.
Characterisation of K+ currents in the C8-B4 microglial cell line and their regulation by microglia activating stimuli.
Cell. Physiol. Biochem.,
2009
, 24 (141-52).
381
Kharche S
et al.
Atrial proarrhythmia due to increased inward rectifier current (I(K1)) arising from KCNJ2 mutation--a simulation study.
Prog. Biophys. Mol. Biol.,
2008 Oct-Nov
, 98 (186-97).
382
Grunnet M
et al.
hERG1 channel activators: a new anti-arrhythmic principle.
Prog. Biophys. Mol. Biol.,
2008 Oct-Nov
, 98 (347-62).
383
Jin T
et al.
Stoichiometry of Kir channels with phosphatidylinositol bisphosphate.
Channels (Austin),
2008 Jan-Feb
, 2 (19-33).
384
Zampini V
et al.
Elementary properties of Kir2.1, a strong inwardly rectifying K(+) channel expressed by pigeon vestibular type II hair cells.
Neuroscience,
2008
Sep
9
, 155 (1250-61).
385
Hernandez CC
et al.
A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.
J. Gen. Physiol.,
2008
Sep
, 132 (361-81).
386
Yang D
et al.
Expression of inwardly rectifying potassium channel subunits in native human retinal pigment epithelium.
Exp. Eye Res.,
2008
Sep
, 87 (176-83).
387
Saenz del Burgo L
et al.
Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.
J. Comp. Neurol.,
2008
Oct
20
, 510 (581-606).
388
Okada M
et al.
Chronic lentiviral expression of inwardly rectifying K+ channels (Kir2.1) reduces neuronal activity and downregulates voltage-gated potassium currents in hippocampus.
Neuroscience,
2008
Oct
2
, 156 (289-97).
389
Park WS
et al.
Physiological role of inward rectifier K(+) channels in vascular smooth muscle cells.
Pflugers Arch.,
2008
Oct
, 457 (137-47).
390
Yontar OC
et al.
Short QT syndrome: a very rare arrhythmogenic entity.
Acta Cardiol,
2008
Oct
, 63 (553-5).
391
Klose A
et al.
1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U73122) selectively inhibits Kir3 and BK channels in a phospholipase C-independent fashion.
Mol. Pharmacol.,
2008
Nov
, 74 (1203-14).
392
Sosulina L
et al.
Neuropeptide Y activates a G-protein-coupled inwardly rectifying potassium current and dampens excitability in the lateral amygdala.
Mol. Cell. Neurosci.,
2008
Nov
, 39 (491-8).
393
Pouget J
[A new type of periodic paralysis: Andersen-Tawil syndrome]
Bull. Acad. Natl. Med.,
2008
Nov
, 192 (1551-6; discussion 1556-7).
394
Zhao Z
et al.
Molecular basis for genistein-induced inhibition of Kir2.3 currents.
Pflugers Arch.,
2008
May
, 456 (413-23).
395
Schimpf R
et al.
Clinical and molecular genetics of the short QT syndrome.
Curr. Opin. Cardiol.,
2008
May
, 23 (192-8).
396
Millar ID
et al.
Kv1 and Kir2 potassium channels are expressed in rat brain endothelial cells.
Pflugers Arch.,
2008
May
, 456 (379-91).
397
Jansen JA
et al.
Lysosome mediated Kir2.1 breakdown directly influences inward rectifier current density.
Biochem. Biophys. Res. Commun.,
2008
Mar
14
, 367 (687-92).
398
Veeraraghavan R
et al.
Mechanisms underlying increased right ventricular conduction sensitivity to flecainide challenge.
Cardiovasc. Res.,
2008
Mar
1
, 77 (749-56).
399
Hinard V
et al.
Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242.
Development,
2008
Mar
, 135 (859-67).
400
Grasser E
et al.
Subunit stoichiometry of heterologously expressed G-protein activated inwardly rectifying potassium channels analysed by fluorescence intensity ratio measurement.
Pflugers Arch.,
2008
Mar
, 455 (1017-24).
401
Marionneau C
et al.
Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.
Circ. Res.,
2008
Jun
6
, 102 (1406-15).
402
Perry CA
et al.
Predisposition to late-onset obesity in GIRK4 knockout mice.
Proc. Natl. Acad. Sci. U.S.A.,
2008
Jun
10
, 105 (8148-53).
403
Tsai CT
et al.
Molecular genetics of atrial fibrillation.
J. Am. Coll. Cardiol.,
2008
Jul
22
, 52 (241-50).
404
Pravetoni M
et al.
Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.
Genes Brain Behav.,
2008
Jul
, 7 (523-31).
405
Hassinen M
et al.
A novel inwardly rectifying K+ channel, Kir2.5, is upregulated under chronic cold stress in fish cardiac myocytes.
J. Exp. Biol.,
2008
Jul
, 211 (2162-71).
406
Rodríguez-Menchaca AA
et al.
The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel.
Proc. Natl. Acad. Sci. U.S.A.,
2008
Jan
29
, 105 (1364-8).
407
Chilton L
et al.
Inward rectifier K+ currents and Kir2.1 expression in renal afferent and efferent arterioles.
J. Am. Soc. Nephrol.,
2008
Jan
, 19 (69-76).
408
Park HJ
et al.
Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.
J. Clin. Invest.,
2008
Jan
, 118 (259-71).
409
Zitron E
et al.
Kir2.x inward rectifier potassium channels are differentially regulated by adrenergic alpha1A receptors.
J. Mol. Cell. Cardiol.,
2008
Jan
, 44 (84-94).
410
Kang SJ
et al.
Expression of Kir2.1 channels in astrocytes under pathophysiological conditions.
Mol. Cells,
2008
Feb
29
, 25 (124-30).
411
Yankelson L
et al.
Cell therapy for modification of the myocardial electrophysiological substrate.
Circulation,
2008
Feb
12
, 117 (720-31).
412
Howe MW
et al.
Cellular and subcellular localization of Kir2.1 subunits in neurons and glia in piriform cortex with implications for K+ spatial buffering.
J. Comp. Neurol.,
2008
Feb
10
, 506 (877-93).
413
Ulbricht E
et al.
Proliferative gliosis causes mislocation and inactivation of inwardly rectifying K(+) (Kir) channels in rabbit retinal glial cells.
Exp. Eye Res.,
2008
Feb
, 86 (305-13).
414
Hashimoto N
et al.
Characterization of in vivo and in vitro electrophysiological and antiarrhythmic effects of a novel IKACh blocker, NIP-151: a comparison with an IKr-blocker dofetilide.
J. Cardiovasc. Pharmacol.,
2008
Feb
, 51 (162-9).
415
Ren C
et al.
Nerve sprouting suppresses myocardial I(to) and I(K1) channels and increases severity to ventricular fibrillation in rat.
,
2008
Dec
15
, 144 (22-9).
416
Robertson JL
et al.
Long-pore electrostatics in inward-rectifier potassium channels.
J. Gen. Physiol.,
2008
Dec
, 132 (613-32).
417
Park KS
et al.
Diversity of ion channels in human bone marrow mesenchymal stem cells from amyotrophic lateral sclerosis patients.
Korean J. Physiol. Pharmacol.,
2008
Dec
, 12 (337-42).
418
Lewandowski R
et al.
RXP-E: a connexin43-binding peptide that prevents action potential propagation block.
Circ. Res.,
2008
Aug
29
, 103 (519-26).
419
Brevet M
et al.
Expression of K+ channels in normal and cancerous human breast.
Histol. Histopathol.,
2008
Aug
, 23 (965-72).
420
Ehrlich JR
Inward rectifier potassium currents as a target for atrial fibrillation therapy.
J. Cardiovasc. Pharmacol.,
2008
Aug
, 52 (129-35).
421
Xie LH
et al.
Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity.
J. Physiol. (Lond.),
2008
Apr
1
, 586 (1833-48).
422
Hernandez CC
et al.
Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
J. Physiol. (Lond.),
2008
Apr
1
, 586 (1811-21).
423
Aguado C
et al.
Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum.
J. Neurochem.,
2008
Apr
, 105 (497-511).
424
Wu Y
et al.
Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila.
J. Biol. Rhythms,
2008
Apr
, 23 (117-28).
425
Fu JD
et al.
An inducible transgene expression system for regulated phenotypic modification of human embryonic stem cells.
Stem Cells Dev.,
2008
Apr
, 17 (315-24).
426
Beckmann C
et al.
G protein-activated (GIRK) current in rat ventricular myocytes is masked by constitutive inward rectifier current (I(K1)).
Cell. Physiol. Biochem.,
2008
, 21 (259-68).
427
Ureche ON
et al.
Novel insights into the structural basis of pH-sensitivity in inward rectifier K+ channels Kir2.3.
Cell. Physiol. Biochem.,
2008
, 21 (347-56).
428
Drago A
et al.
Strategy for a genetic assessment of antipsychotic and antidepressant-related proarrhythmia.
Curr. Med. Chem.,
2008
, 15 (2472-517).
429
Ruan Q
et al.
Topological and developmental expression gradients of Kir2.1, an inward rectifier K+ channel, in spiral ganglion and cochlear hair cells of mouse inner ear.
Dev. Neurosci.,
2008
, 30 (374-88).
430
Yoon YJ
et al.
Inhibition of electrical activity by retroviral infection with Kir2.1 transgenes disrupts electrical differentiation of motoneurons.
PLoS ONE,
2008
, 3 (e2971).
431
Ballester LY
et al.
Exaggerated Mg2+ inhibition of Kir2.1 as a consequence of reduced PIP2 sensitivity in Andersen syndrome.
Channels (Austin),
2007 May-Jun
, 1 (209-17).
432
Inanobe A
et al.
Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
Channels (Austin),
2007 Jan-Feb
, 1 (39-45).
433
Nikolov EN
et al.
Dynamic integration of alpha-adrenergic and cholinergic signals in the atria: role of G protein-regulated inwardly rectifying K+ channels.
J. Biol. Chem.,
2007
Sep
28
, 282 (28669-82).
434
Ishihara K
et al.
Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.
J. Physiol. (Lond.),
2007
Sep
15
, 583 (891-908).
435
Murata Y
et al.
Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2.
J. Physiol. (Lond.),
2007
Sep
15
, 583 (875-89).
436
Hardie SL
et al.
Trace amines differentially regulate adult locomotor activity, cocaine sensitivity, and female fertility in Drosophila melanogaster.
Dev Neurobiol,
2007
Sep
1
, 67 (1396-405).
437
Decher N
et al.
Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.
Cardiovasc. Res.,
2007
Sep
1
, 75 (748-57).
438
Aizawa Y
et al.
A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome.
J. Cardiovasc. Electrophysiol.,
2007
Sep
, 18 (972-7).
439
Piao L
et al.
Transgenic upregulation of IK1 in the mouse heart is proarrhythmic.
Basic Res. Cardiol.,
2007
Sep
, 102 (416-28).
440
Ohno Y
et al.
Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors.
Brain Res.,
2007
Oct
31
, 1178 (44-51).
441
Duale H
et al.
Restraining influence of A2 neurons in chronic control of arterial pressure in spontaneously hypertensive rats.
Cardiovasc. Res.,
2007
Oct
1
, 76 (184-93).
442
Putzke C
et al.
Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1.
Am. J. Physiol., Cell Physiol.,
2007
Oct
, 293 (C1319-26).
443
Lunn ML
et al.
A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.
Nat. Neurosci.,
2007
Oct
, 10 (1249-59).
444
Tao R
et al.
Functional ion channels in mouse bone marrow mesenchymal stem cells.
Am. J. Physiol., Cell Physiol.,
2007
Nov
, 293 (C1561-7).
445
Sekar RB
et al.
Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity.
Am. J. Physiol. Heart Circ. Physiol.,
2007
Nov
, 293 (H2757-70).
446
Yanagi K
et al.
Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes.
Stem Cells,
2007
Nov
, 25 (2712-9).
447
Wei YP
et al.
[Primary cultured neonate rat sinus node cells: morphology and expression of kir2.1 protein]
Nan Fang Yi Ke Da Xue Xue Bao,
2007
Nov
, 27 (1701-5).
448
Pegan S
et al.
NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95.
Biochemistry,
2007
May
8
, 46 (5315-22).
449
Wedemeyer C
et al.
Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes.
Eur. J. Pharmacol.,
2007
May
21
, 562 (165-73).
451
Liu B
et al.
Selective inhibition of Kir currents by antihistamines.
Eur. J. Pharmacol.,
2007
Mar
8
, 558 (21-6).
452
Teutsch C
et al.
Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection.
Cardiovasc. Res.,
2007
Mar
1
, 73 (739-49).
454
Extramiana F
Screening for KCNJ2 mutations: the physician's perspective.
Heart Rhythm,
2007
Mar
, 4 (330-1).
455
Eckhardt LL
et al.
KCNJ2 mutations in arrhythmia patients referred for LQT testing: a mutation T305A with novel effect on rectification properties.
Heart Rhythm,
2007
Mar
, 4 (323-9).
456
Jakobsen LP
et al.
Pierre Robin sequence may be caused by dysregulation of SOX9 and KCNJ2.
J. Med. Genet.,
2007
Jun
, 44 (381-6).
457
Hassinen M
et al.
Cloning and expression of cardiac Kir2.1 and Kir2.2 channels in thermally acclimated rainbow trout.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2007
Jun
, 292 (R2328-39).
458
Kobayashi T
et al.
Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes.
Toxicol In Vitro,
2007
Jun
, 21 (656-64).
459
Gaborit N
et al.
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
J. Physiol. (Lond.),
2007
Jul
15
, 582 (675-93).
460
Scherer D
et al.
Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2.
Naunyn Schmiedebergs Arch. Pharmacol.,
2007
Jul
, 375 (311-22).
461
Tikku S
et al.
Relationship between Kir2.1/Kir2.3 activity and their distributions between cholesterol-rich and cholesterol-poor membrane domains.
Am. J. Physiol., Cell Physiol.,
2007
Jul
, 293 (C440-50).
462
Arnestad M
et al.
Prevalence of long-QT syndrome gene variants in sudden infant death syndrome.
Circulation,
2007
Jan
23
, 115 (361-7).
463
Domenighetti AA
et al.
Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation.
J. Mol. Cell. Cardiol.,
2007
Jan
, 42 (63-70).
464
Hara K
et al.
Inhibitory effect of gabapentin on N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
,
2007
Jan
, 51 (122-8).
465
Hasenbrink G
et al.
Ring test assessment of the mKir2.1 growth based assay in Saccharomyces cerevisiae using parametric models and model-free fits.
Appl. Microbiol. Biotechnol.,
2007
Jan
, 73 (1212-21).
466
Sun Y
et al.
EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients.
Am. J. Physiol., Cell Physiol.,
2007
Jan
, 292 (C106-14).
467
Ma D
et al.
An andersen-Tawil syndrome mutation in Kir2.1 (V302M) alters the G-loop cytoplasmic K+ conduction pathway.
J. Biol. Chem.,
2007
Feb
23
, 282 (5781-9).
468
Harrell MD
et al.
Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.
Physiol. Genomics,
2007
Feb
12
, 28 (273-83).
469
Brouillette J
et al.
Characterization of ventricular repolarization in male and female guinea pigs.
J. Mol. Cell. Cardiol.,
2007
Feb
, 42 (357-66).
470
Su S
et al.
Inhibition of astroglial inwardly rectifying Kir4.1 channels by a tricyclic antidepressant, nortriptyline.
J. Pharmacol. Exp. Ther.,
2007
Feb
, 320 (573-80).
471
Chang HK
et al.
Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels.
J. Membr. Biol.,
2007
Feb
, 215 (181-93).
472
Haruna Y
et al.
Genotype-phenotype correlations of KCNJ2 mutations in Japanese patients with Andersen-Tawil syndrome.
Hum. Mutat.,
2007
Feb
, 28 (208).
473
Goult BT
et al.
Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1.
Biochemistry,
2007
Dec
11
, 46 (14117-28).
474
Panama BK
et al.
Heterogeneity of IK1 in the mouse heart.
Am. J. Physiol. Heart Circ. Physiol.,
2007
Dec
, 293 (H3558-67).
475
Hayashi M
et al.
Negatively charged residues located near the external entrance are required for the Kir2.1 channel to function.
Pflugers Arch.,
2007
Dec
, 455 (455-64).
476
Juel C
et al.
K+ as a vasodilator in resting human muscle: implications for exercise hyperaemia.
Acta Physiol (Oxf),
2007
Aug
, 190 (311-8).
477
Kurata HT
et al.
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels.
J. Gen. Physiol.,
2007
Aug
, 130 (145-55).
478
Park KS
et al.
Functional expression of ion channels in mesenchymal stem cells derived from umbilical cord vein.
Stem Cells,
2007
Aug
, 25 (2044-52).
479
Tani Y
et al.
T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity.
J. Mol. Cell. Cardiol.,
2007
Aug
, 43 (187-96).
480
Zuzarte M
et al.
A di-acidic sequence motif enhances the surface expression of the potassium channel TASK-3.
Traffic,
2007
Aug
, 8 (1093-100).
481
Bendahhou S
et al.
Corticosteroid-exacerbated symptoms in an Andersen's syndrome kindred.
Hum. Mol. Genet.,
2007
Apr
15
, 16 (900-6).
482
Nagase S
et al.
Electrophysiologic characteristics of an Andersen syndrome patient with KCNJ2 mutation.
,
2007
Apr
, 4 (512-5).
483
Kawano T
et al.
Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.
Mol. Pharmacol.,
2007
Apr
, 71 (1179-84).
484
Sansone V
et al.
Management and treatment of Andersen-Tawil syndrome (ATS).
,
2007
Apr
, 4 (233-7).
485
Yang B
et al.
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2.
Nat. Med.,
2007
Apr
, 13 (486-91).
486
Muñoz V
et al.
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells.
Heart Rhythm,
2007
Apr
, 4 (487-96).
487
Volders PG
et al.
Mapping a novel locus for familial atrial fibrillation on chromosome 10p11-q21.
Heart Rhythm,
2007
Apr
, 4 (469-75).
488
Choi BO
et al.
Mutations of KCNJ2 gene associated with Andersen-Tawil syndrome in Korean families.
J. Hum. Genet.,
2007
, 52 (280-3).
489
Steinecker B
et al.
The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J. Recept. Signal Transduct. Res.,
2007
, 27 (369-82).
490
Fülöp L
et al.
Effects of sex hormones on ECG parameters and expression of cardiac ion channels in dogs.
Acta Physiol (Oxf),
2006 Nov-Dec
, 188 (163-71).
491
Thum AS
et al.
Differential potencies of effector genes in adult Drosophila.
J. Comp. Neurol.,
2006
Sep
10
, 498 (194-203).
492
Shumilina E
et al.
Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels.
J. Physiol. (Lond.),
2006
Sep
1
, 575 (433-42).
493
Jantzi MC
et al.
Inward rectifying potassium channels facilitate cell-to-cell communication in hamster retractor muscle feed arteries.
Am. J. Physiol. Heart Circ. Physiol.,
2006
Sep
, 291 (H1319-28).
494
Tengan CH
et al.
Andersen syndrome: an association of periodic paralysis, cardiac arrhythmia and dysmorphic abnormalities.
,
2006
Sep
, 64 (582-4).
495
Grishin A
et al.
Identification of gamma-aminobutyric acid receptor-interacting factor 1 (TRAK2) as a trafficking factor for the K+ channel Kir2.1.
J. Biol. Chem.,
2006
Oct
6
, 281 (30104-11).
496
Marker CL
et al.
Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels.
J. Neurosci.,
2006
Nov
22
, 26 (12251-9).
497
Kobayashi T
et al.
Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine.
J. Pharmacol. Sci.,
2006
Nov
, 102 (278-87).
498
Iwasaki YK
et al.
A method for the simultaneous analysis of mRNA levels of multiple cardiac ion channels with a multi-probe RNase protection assay.
,
2006
Nov
, 8 (1011-5).
499
Dobrzynski H
et al.
Expression of Kir2.1 and Kir6.2 transgenes under the control of the alpha-MHC promoter in the sinoatrial and atrioventricular nodes in transgenic mice.
J. Mol. Cell. Cardiol.,
2006
Nov
, 41 (855-67).
500
Del Re AM
et al.
Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes.
Brain Res.,
2006
May
4
, 1087 (75-82).
501
Sackin H
et al.
Role of conserved glycines in pH gating of Kir1.1 (ROMK).
Biophys. J.,
2006
May
15
, 90 (3582-9).
502
Iandiev I
et al.
Glial cell reactivity in a porcine model of retinal detachment.
Invest. Ophthalmol. Vis. Sci.,
2006
May
, 47 (2161-71).
503
Fernández-Velasco M
et al.
I K1 and I f in ventricular myocytes isolated from control and hypertrophied rat hearts.
Pflugers Arch.,
2006
May
, 452 (146-54).
504
Kurata HT
et al.
The polyamine binding site in inward rectifier K+ channels.
J. Gen. Physiol.,
2006
May
, 127 (467-80).
505
Rossignol TM
et al.
Regulation of a family of inwardly rectifying potassium channels (Kir2) by the m1 muscarinic receptor and the small GTPase Rho.
Pflugers Arch.,
2006
May
, 452 (164-74).
506
Sun H
et al.
Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.
J. Biol. Chem.,
2006
Mar
3
, 281 (5877-84).
507
Iandiev I
et al.
Differential regulation of Kir4.1 and Kir2.1 expression in the ischemic rat retina.
Neurosci. Lett.,
2006
Mar
27
, 396 (97-101).
508
Panama BK
et al.
Differential polyamine sensitivity in inwardly rectifying Kir2 potassium channels.
J. Physiol. (Lond.),
2006
Mar
1
, 571 (287-302).
509
Tsuboi M
et al.
Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7).
Heart Rhythm,
2006
Mar
, 3 (328-35).
510
Kristensen M
et al.
Membrane proteins involved in potassium shifts during muscle activity and fatigue.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2006
Mar
, 290 (R766-72).
511
Kobayashi T
et al.
Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Neuropsychopharmacology,
2006
Mar
, 31 (516-24).
512
Yoon G
et al.
Andersen-Tawil syndrome: definition of a neurocognitive phenotype.
Neurology,
2006
Jun
13
, 66 (1703-10).
513
Liu WL
et al.
[Novel mutations of potassium channel KCNQ1 S145L and KCNH2 Y475C genes in Chinese pedigrees of long QT syndrome]
Zhonghua Nei Ke Za Zhi,
2006
Jun
, 45 (463-6).
514
Pegan S
et al.
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1.
Biochemistry,
2006
Jul
18
, 45 (8599-606).
515
Tolokh IS
et al.
Unified modeling of conductance kinetics for low- and high-conductance potassium ion channels.
,
2006
Jul
, 74 (011902).
516
de Boer TP
et al.
Inhibition of cardiomyocyte automaticity by electrotonic application of inward rectifier current from Kir2.1 expressing cells.
,
2006
Jul
, 44 (537-42).
517
Benfenati V
et al.
Guanosine promotes the up-regulation of inward rectifier potassium current mediated by Kir4.1 in cultured rat cortical astrocytes.
J. Neurochem.,
2006
Jul
, 98 (430-45).
518
Tester DJ
et al.
Genotypic heterogeneity and phenotypic mimicry among unrelated patients referred for catecholaminergic polymorphic ventricular tachycardia genetic testing.
Heart Rhythm,
2006
Jul
, 3 (800-5).
519
Pondugula SR
et al.
Glucocorticoid regulation of genes in the amiloride-sensitive sodium transport pathway by semicircular canal duct epithelium of neonatal rat.
Physiol. Genomics,
2006
Jan
12
, 24 (114-23).
520
Falk T
et al.
Neurochemical and electrophysiological characteristics of rat striatal neurons in primary culture.
J. Comp. Neurol.,
2006
Jan
10
, 494 (275-89).
521
Venance SL
et al.
The primary periodic paralyses: diagnosis, pathogenesis and treatment.
Brain,
2006
Jan
, 129 (8-17).
522
Kiesecker C
et al.
Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.
J. Mol. Med.,
2006
Jan
, 84 (46-56).
523
Zhang Y
et al.
[Human inward rectifying potassium current and Kir2.1 mRNA expression in myocytes isolated from patients with chronic atrial fibrillation]
,
2006
Jan
, 34 (33-7).
524
Yoon G
et al.
Andersen-Tawil syndrome: prospective cohort analysis and expansion of the phenotype.
Am. J. Med. Genet. A,
2006
Feb
15
, 140 (312-21).
525
Harashima C
et al.
Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome.
J. Comp. Neurol.,
2006
Feb
10
, 494 (815-33).
526
Novotný T
et al.
[Mutational analysis of LQT genes in individuals with drug induced QT interval prolongation]
,
2006
Feb
, 52 (116-8).
527
He Y
et al.
Stretch-induced alterations of human Kir2.1 channel currents.
Biochem. Biophys. Res. Commun.,
2006
Dec
15
, 351 (462-7).
528
Sung RJ
et al.
Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: a simulation study.
Am. J. Physiol. Heart Circ. Physiol.,
2006
Dec
, 291 (H2597-605).
529
Sordel T
et al.
Hourglass SiO2 coating increases the performance of planar patch-clamp.
J. Biotechnol.,
2006
Aug
20
, 125 (142-54).
530
Konig S
et al.
The calcineurin pathway links hyperpolarization (Kir2.1)-induced Ca2+ signals to human myoblast differentiation and fusion.
Development,
2006
Aug
, 133 (3107-14).
531
Matsuda T
et al.
Blockade by NIP-142, an antiarrhythmic agent, of carbachol-induced atrial action potential shortening and GIRK1/4 channel.
J. Pharmacol. Sci.,
2006
Aug
, 101 (303-10).
532
Lu CW
et al.
Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome.
J. Med. Genet.,
2006
Aug
, 43 (653-9).
533
Lei XJ
et al.
[Inhibition of human macrophage-derived foam cell differentiation by blocking Kv1.3 and Kir2.1 channels]
Zhong Nan Da Xue Xue Bao Yi Xue Ban,
2006
Aug
, 31 (493-8).
534
Ballester LY
et al.
Trafficking-competent and trafficking-defective KCNJ2 mutations in Andersen syndrome.
Hum. Mutat.,
2006
Apr
, 27 (388).
535
Fujiwara Y
et al.
Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1.
J. Gen. Physiol.,
2006
Apr
, 127 (401-19).
536
Rinne A
et al.
Gene silencing in adult rat cardiac myocytes in vitro by adenovirus-mediated RNA interference.
J. Muscle Res. Cell. Motil.,
2006
, 27 (413-21).
537
Gałęza-Kulik M
et al.
[Expression of selected genes involved in transport of ions in papillary thyroid carcinoma.]
,
2006
, 57 (26-31).
538
Dhar MS
et al.
Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells.
BMC Physiol.,
2006
, 6 (8).
539
Tennant BP
et al.
Functional expression of inward rectifier potassium channels in cultured human pulmonary smooth muscle cells: evidence for a major role of Kir2.4 subunits.
J. Membr. Biol.,
2006
, 213 (19-29).
540
Bundis F
et al.
Involvement of Golgin-160 in cell surface transport of renal ROMK channel: co-expression of Golgin-160 increases ROMK currents.
Cell. Physiol. Biochem.,
2006
, 17 (1-12).
541
Ellinor PT
et al.
Potassium channel gene mutations rarely cause atrial fibrillation.
BMC Med. Genet.,
2006
, 7 (70).
542
Rapedius M
et al.
Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels.
J. Biol. Chem.,
2005
Sep
2
, 280 (30760-7).
543
Newell EW
et al.
Integration of K+ and Cl- currents regulate steady-state and dynamic membrane potentials in cultured rat microglia.
J. Physiol. (Lond.),
2005
Sep
15
, 567 (869-90).
544
Chatelain FC
et al.
The pore helix dipole has a minor role in inward rectifier channel function.
Neuron,
2005
Sep
15
, 47 (833-43).
545
Prüss H
et al.
Differential distribution of individual subunits of strongly inwardly rectifying potassium channels (Kir2 family) in rat brain.
Brain Res. Mol. Brain Res.,
2005
Sep
13
, 139 (63-79).
546
Kanjhan R
et al.
Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner.
J. Pharmacol. Exp. Ther.,
2005
Sep
, 314 (1353-61).
547
Davies NP
et al.
Andersen-Tawil syndrome: new potassium channel mutations and possible phenotypic variation.
Neurology,
2005
Oct
11
, 65 (1083-9).
548
Lei YS
et al.
[Construction of vector tandem expressing rat ventricular myocyte Kir2.1 shRNA and its effect in vitro]
Zhonghua Yi Xue Za Zhi,
2005
Nov
2
, 85 (2910-5).
549
Makary SM
et al.
A difference in inward rectification and polyamine block and permeation between the Kir2.1 and Kir3.1/Kir3.4 K+ channels.
J. Physiol. (Lond.),
2005
Nov
1
, 568 (749-66).
550
Kozak JA
et al.
Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels.
J. Gen. Physiol.,
2005
Nov
, 126 (499-514).
551
Park WS
et al.
Endothelin-1 inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase C.
J. Cardiovasc. Pharmacol.,
2005
Nov
, 46 (681-9).
552
Fang Y
et al.
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.
Am. J. Physiol., Cell Physiol.,
2005
Nov
, 289 (C1134-44).
553
Zhang L
et al.
Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: characteristic T-U-wave patterns predict the KCNJ2 genotype.
Circulation,
2005
May
31
, 111 (2720-6).
554
Liu B
et al.
Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate.
J. Neurosci.,
2005
May
11
, 25 (4835-43).
555
Hofherr A
et al.
Selective Golgi export of Kir2.1 controls the stoichiometry of functional Kir2.x channel heteromers.
J. Cell. Sci.,
2005
May
1
, 118 (1935-43).
556
D'Avanzo N
et al.
Conduction through the inward rectifier potassium channel, Kir2.1, is increased by negatively charged extracellular residues.
J. Gen. Physiol.,
2005
May
, 125 (493-503).
557
Rose J
et al.
Molecular correlates of altered expression of potassium currents in failing rabbit myocardium.
Am. J. Physiol. Heart Circ. Physiol.,
2005
May
, 288 (H2077-87).
558
Ariano MA
et al.
Striatal potassium channel dysfunction in Huntington's disease transgenic mice.
J. Neurophysiol.,
2005
May
, 93 (2565-74).
559
Yan DH
et al.
Different intracellular polyamine concentrations underlie the difference in the inward rectifier K(+) currents in atria and ventricles of the guinea-pig heart.
J. Physiol. (Lond.),
2005
Mar
15
, 563 (713-24).
560
Yan DH
et al.
Two Kir2.1 channel populations with different sensitivities to Mg(2+) and polyamine block: a model for the cardiac strong inward rectifier K(+) channel.
J. Physiol. (Lond.),
2005
Mar
15
, 563 (725-44).
561
Hasenbrink G
et al.
Analysis of the mKir2.1 channel activity in potassium influx defective Saccharomyces cerevisiae strains determined as changes in growth characteristics.
FEBS Lett.,
2005
Mar
14
, 579 (1723-31).
562
Pegan S
et al.
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification.
Nat. Neurosci.,
2005
Mar
, 8 (279-87).
563
Wang R
et al.
Determinant role of membrane helices in K ATP channel gating.
J. Membr. Biol.,
2005
Mar
, 204 (1-10).
564
Li X
et al.
G protein beta2 subunit-derived peptides for inhibition and induction of G protein pathways. Examination of voltage-gated Ca2+ and G protein inwardly rectifying K+ channels.
J. Biol. Chem.,
2005
Jun
24
, 280 (23945-59).
565
Bendahhou S
et al.
In vivo and in vitro functional characterization of Andersen's syndrome mutations.
J. Physiol. (Lond.),
2005
Jun
15
, 565 (731-41).
566
Chilton L
et al.
K+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts.
Am. J. Physiol. Heart Circ. Physiol.,
2005
Jun
, 288 (H2931-9).
567
Akar FG
et al.
Molecular mechanisms underlying K+ current downregulation in canine tachycardia-induced heart failure.
Am. J. Physiol. Heart Circ. Physiol.,
2005
Jun
, 288 (H2887-96).
568
Xia M
et al.
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
Biochem. Biophys. Res. Commun.,
2005
Jul
15
, 332 (1012-9).
569
Gu Y
et al.
Mechanisms of light adaptation in Drosophila photoreceptors.
Curr. Biol.,
2005
Jul
12
, 15 (1228-34).
570
Wolpert C
et al.
Clinical characteristics and treatment of short QT syndrome.
,
2005
Jul
, 3 (611-7).
571
Melnyk P
et al.
Comparison of ion channel distribution and expression in cardiomyocytes of canine pulmonary veins versus left atrium.
Cardiovasc. Res.,
2005
Jan
1
, 65 (104-16).
572
Chang HK
et al.
A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation.
Biophys. J.,
2005
Jan
, 88 (243-54).
573
Collins A
et al.
Regulation of inward rectifier K+ channels by shift of intracellular pH dependence.
J. Cell. Physiol.,
2005
Jan
, 202 (76-86).
574
Sarac R
et al.
Mutation of critical GIRK subunit residues disrupts N- and C-termini association and channel function.
J. Neurosci.,
2005
Feb
16
, 25 (1836-46).
575
Tolokh IS
et al.
Non-Michaelis-Menten kinetics model for conductance of low-conductance potassium ion channels.
,
2005
Feb
, 71 (021912).
576
Koyrakh L
et al.
Molecular and cellular diversity of neuronal G-protein-gated potassium channels.
J. Neurosci.,
2005
Dec
7
, 25 (11468-78).
577
Léoni AL
et al.
Chronic heart rate reduction remodels ion channel transcripts in the mouse sinoatrial node but not in the ventricle.
Physiol. Genomics,
2005
Dec
14
, 24 (4-12).
578
Hardie RC
Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA.
Cell Calcium,
2005
Dec
, 38 (547-56).
579
Park WS
et al.
Activation of inward rectifier K+ channels by hypoxia in rabbit coronary arterial smooth muscle cells.
Am. J. Physiol. Heart Circ. Physiol.,
2005
Dec
, 289 (H2461-7).
580
Xie LH
et al.
Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels.
J. Gen. Physiol.,
2005
Dec
, 126 (541-9).
581
Yeh SH
et al.
Electrostatics in the cytoplasmic pore produce intrinsic inward rectification in kir2.1 channels.
J. Gen. Physiol.,
2005
Dec
, 126 (551-62).
582
Kolacna L
et al.
New phenotypes of functional expression of the mKir2.1 channel in potassium efflux-deficient Saccharomyces cerevisiae strains.
Yeast,
2005
Dec
, 22 (1315-23).
583
Jansen LA
et al.
Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes.
Epilepsia,
2005
Dec
, 46 (1871-80).
584
Lei XJ
et al.
Expression of Kir2.1 channel during differentiation of human macrophages into foam cells.
Di Yi Jun Yi Da Xue Xue Bao,
2005
Dec
, 25 (1461-7).
585
Choi J
et al.
T-type calcium channel trigger p21ras signaling pathway to ERK in Cav3.1-expressed HEK293 cells.
Brain Res.,
2005
Aug
23
, 1054 (22-9).
587
Szabó G
et al.
Asymmetrical distribution of ion channels in canine and human left-ventricular wall: epicardium versus midmyocardium.
Pflugers Arch.,
2005
Aug
, 450 (307-16).
588
Kim MY
et al.
Contribution of Na+-K+ pump and KIR currents to extracellular pH-dependent changes of contractility in rat superior mesenteric artery.
Am. J. Physiol. Heart Circ. Physiol.,
2005
Aug
, 289 (H792-800).
589
Shin HG
et al.
Evidence for sequential ion-binding loci along the inner pore of the IRK1 inward-rectifier K+ channel.
J. Gen. Physiol.,
2005
Aug
, 126 (123-35).
590
Marker CL
et al.
Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids.
J. Neurosci.,
2005
Apr
6
, 25 (3551-9).
591
Rishal I
et al.
Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels.
J. Biol. Chem.,
2005
Apr
29
, 280 (16685-94).
592
Koike-Tani M
et al.
Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel.
J. Physiol. (Lond.),
2005
Apr
15
, 564 (489-500).
593
Schulze-Bahr E
Short QT syndrome or Andersen syndrome: Yin and Yang of Kir2.1 channel dysfunction.
Circ. Res.,
2005
Apr
15
, 96 (703-4).
594
Priori SG
et al.
A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene.
Circ. Res.,
2005
Apr
15
, 96 (800-7).
595
Shin HG
et al.
Mechanism of the voltage sensitivity of IRK1 inward-rectifier K+ channel block by the polyamine spermine.
J. Gen. Physiol.,
2005
Apr
, 125 (413-26).
596
Takahashi T
et al.
KCNJ2 mutation in intractable ventricular arrhythmia with Andersen's syndrome.
Pediatr Int,
2005
Apr
, 47 (220-3).
597
Schalin-Jantti C
et al.
Manifestation, management and molecular analysis of candidate genes in two rare cases of thyrotoxic hypokalemic periodic paralysis.
Horm. Res.,
2005
, 63 (139-44).
598
Yakubovich D
et al.
Kinetic modeling of Na(+)-induced, Gbetagamma-dependent activation of G protein-gated K(+) channels.
J. Mol. Neurosci.,
2005
, 25 (7-19).
599
Pertovaara A
et al.
RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.
Neuroscience,
2005
, 134 (1023-32).
600
Plummer HK
et al.
Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.
BMC Cancer,
2005
, 5 (104).
601
Biskup C
et al.
Interaction of PSD-95 with potassium channels visualized by fluorescence lifetime-based resonance energy transfer imaging.
,
2004 Jul-Aug
, 9 (753-9).
602
Shankar H
et al.
Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.
Blood,
2004
Sep
1
, 104 (1335-43).
603
Satin J
et al.
Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes.
J. Physiol. (Lond.),
2004
Sep
1
, 559 (479-96).
604
Filippov AK
et al.
Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors.
Mol. Pharmacol.,
2004
Sep
, 66 (468-77).
605
Correia MJ
et al.
Molecular characterization of an inward rectifier channel (IKir) found in avian vestibular hair cells: cloning and expression of pKir2.1.
Physiol. Genomics,
2004
Oct
4
, 19 (155-69).
606
Leyland ML
et al.
An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1.
J. Biol. Chem.,
2004
Oct
15
, 279 (43427-36).
607
Leichtle A
et al.
Electrophysiological and molecular characterization of the inward rectifier in juxtaglomerular cells from rat kidney.
J. Physiol. (Lond.),
2004
Oct
15
, 560 (365-76).
608
Choi G
et al.
Spectrum and frequency of cardiac channel defects in swimming-triggered arrhythmia syndromes.
Circulation,
2004
Oct
12
, 110 (2119-24).
609
Kobayashi T
et al.
Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users.
Ann. N. Y. Acad. Sci.,
2004
Oct
, 1025 (590-4).
610
Sun H
et al.
Inward rectifier potassium channels in the basilar artery during chronic alcohol consumption.
Alcohol. Clin. Exp. Res.,
2004
Oct
, 28 (1557-61).
611
Kobayashi T
et al.
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Neuropsychopharmacology,
2004
Oct
, 29 (1841-51).
612
Miller TM
et al.
Correlating phenotype and genotype in the periodic paralyses.
Neurology,
2004
Nov
9
, 63 (1647-55).
613
Kim T
et al.
The biochemical activation of T-type Ca2+ channels in HEK293 cells stably expressing alpha1G and Kir2.1 subunits.
Biochem. Biophys. Res. Commun.,
2004
Nov
5
, 324 (401-8).
614
Sun H
et al.
Function recovery after chemobleaching (FRAC): evidence for activity silent membrane receptors on cell surface.
Proc. Natl. Acad. Sci. U.S.A.,
2004
Nov
30
, 101 (16964-9).
615
Mutai H
et al.
Characterization of the chicken inward rectifier K+ channel IRK1/Kir2.1 gene.
BMC Genomics,
2004
Nov
29
, 5 (90).
616
Xie LH
et al.
Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel.
J. Physiol. (Lond.),
2004
Nov
15
, 561 (159-68).
617
Takanami I
et al.
G-protein inwardly rectifying potassium channel 1 (GIRK 1) gene expression correlates with tumor progression in non-small cell lung cancer.
BMC Cancer,
2004
Nov
13
, 4 (79).
618
Hardie RC
et al.
In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).
J. Biol. Chem.,
2004
Nov
12
, 279 (47773-82).
619
McAllister SD
et al.
Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation.
J. Biol. Chem.,
2004
Nov
12
, 279 (48024-37).
620
Yang Y
et al.
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation.
Am. J. Hum. Genet.,
2004
Nov
, 75 (899-905).
621
Nikolov EN
et al.
Coordination of membrane excitability through a GIRK1 signaling complex in the atria.
J. Biol. Chem.,
2004
May
28
, 279 (23630-6).
622
Dhamoon AS
et al.
Unique Kir2.x properties determine regional and species differences in the cardiac inward rectifier K+ current.
Circ. Res.,
2004
May
28
, 94 (1332-9).
623
Yu CR
et al.
Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map.
Neuron,
2004
May
27
, 42 (553-66).
624
Leonoudakis D
et al.
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.
J. Biol. Chem.,
2004
May
21
, 279 (22331-46).
625
Pil J
et al.
Synthesis and electrophysiological characterization of cyclic morphiceptin analogues.
Biochem. Pharmacol.,
2004
May
15
, 67 (1887-95).
626
Pouget J
et al.
[Andersen syndrome: a particular form of paralysis with cardiac dysrhythmia]
Rev. Neurol. (Paris),
2004
May
, 160 (S38-42).
627
Mirshahi T
et al.
Molecular determinants responsible for differential cellular distribution of G protein-gated inwardly rectifying K+ channels.
J. Biol. Chem.,
2004
Mar
19
, 279 (11890-7).
628
Kawano T
et al.
Single-cell RT-PCR analysis of GIRK channels expressed in rat locus coeruleus and nucleus basalis neurons.
Neurosci. Lett.,
2004
Mar
18
, 358 (63-7).
629
Marker CL
et al.
Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.
J. Neurosci.,
2004
Mar
17
, 24 (2806-12).
630
Finley M
et al.
betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation.
J. Physiol. (Lond.),
2004
Mar
16
, 555 (643-57).
631
Malinowska DH
et al.
Gastric parietal cell secretory membrane contains PKA- and acid-activated Kir2.1 K+ channels.
Am. J. Physiol., Cell Physiol.,
2004
Mar
, 286 (C495-506).
632
Forte JG
K+ channels in the secretory membrane of the parietal cell. focus on "Gastric parietal cell secretory membrane contains PKA- and acid-activated Kir2.1 K+ channels".
Am. J. Physiol., Cell Physiol.,
2004
Mar
, 286 (C478-9).
633
Guo J
et al.
Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons.
Mol. Pharmacol.,
2004
Mar
, 65 (665-74).
634
Edwards G
et al.
Potassium and potassium clouds in endothelium-dependent hyperpolarizations.
Pharmacol. Res.,
2004
Jun
, 49 (535-41).
635
Konig S
et al.
Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.
J. Biol. Chem.,
2004
Jul
2
, 279 (28187-96).
636
Tristani-Firouzi M
Polymorphic ventricular tachycardia associated with mutations in KCNJ2.
Heart Rhythm,
2004
Jul
, 1 (242-3).
637
Chun TU
et al.
Polymorphic ventricular tachycardia and KCNJ2 mutations.
Heart Rhythm,
2004
Jul
, 1 (235-41).
638
Mao J
et al.
Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C.
Proc. Natl. Acad. Sci. U.S.A.,
2004
Jan
27
, 101 (1087-92).
639
Zaks-Makhina E
et al.
Novel neuroprotective K+ channel inhibitor identified by high-throughput screening in yeast.
Mol. Pharmacol.,
2004
Jan
, 65 (214-9).
640
Zhang L
et al.
Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction.
J. Biol. Chem.,
2004
Feb
20
, 279 (7037-47).
641
Kobori A
et al.
Additional gene variants reduce effectiveness of beta-blockers in the LQT1 form of long QT syndrome.
J. Cardiovasc. Electrophysiol.,
2004
Feb
, 15 (190-9).
642
Plummer HK
et al.
Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines.
BMC Cancer,
2004
Dec
16
, 4 (93).
643
Xu Y
et al.
Characterization of inward-rectifier K+ channel inhibition by antiarrhythmic piperazine.
Biochemistry,
2004
Dec
14
, 43 (15577-83).
644
Labrador V
et al.
Peptidyl-glycine alpha-amidating monooxygenase targeting and shaping of atrial secretory vesicles: inhibition by mutated N-terminal ProANP and PBA.
Circ. Res.,
2004
Dec
10
, 95 (e98-109).
645
Wellner-Kienitz MC
et al.
Voltage dependence of ATP-dependent K+ current in rat cardiac myocytes is affected by IK1 and IK(ACh).
J. Physiol. (Lond.),
2004
Dec
1
, 561 (459-69).
646
Bender K
et al.
Acute desensitization of GIRK current in rat atrial myocytes is related to K+ current flow.
J. Physiol. (Lond.),
2004
Dec
1
, 561 (471-83).
647
Sánchez-Chapula JA
et al.
Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine.
Naunyn Schmiedebergs Arch. Pharmacol.,
2004
Dec
, 370 (484-91).
648
Romanenko VG
et al.
Cholesterol sensitivity and lipid raft targeting of Kir2.1 channels.
Biophys. J.,
2004
Dec
, 87 (3850-61).
649
Zhang YY
et al.
Carboxy-terminal determinants of conductance in inward-rectifier K channels.
J. Gen. Physiol.,
2004
Dec
, 124 (729-39).
650
Li J
et al.
Transgenic upregulation of IK1 in the mouse heart leads to multiple abnormalities of cardiac excitability.
Am. J. Physiol. Heart Circ. Physiol.,
2004
Dec
, 287 (H2790-802).
651
Diaz RJ
et al.
Selective inhibition of inward rectifier K+ channels (Kir2.1 or Kir2.2) abolishes protection by ischemic preconditioning in rabbit ventricular cardiomyocytes.
Circ. Res.,
2004
Aug
6
, 95 (325-32).
652
Ramu Y
et al.
Short variable sequence acquired in evolution enables selective inhibition of various inward-rectifier K+ channels.
Biochemistry,
2004
Aug
24
, 43 (10701-9).
653
Zitron E
et al.
Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A.
Cardiovasc. Res.,
2004
Aug
15
, 63 (520-7).
654
Milovic S
et al.
The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.
J. Biol. Chem.,
2004
Aug
13
, 279 (34240-9).
655
Vicente R
et al.
The systemic inflammatory response is involved in the regulation of K(+) channel expression in brain via TNF-alpha-dependent and -independent pathways.
FEBS Lett.,
2004
Aug
13
, 572 (189-94).
656
Chen L
et al.
Inwardly rectifying potassium channels in rat retinal ganglion cells.
Eur. J. Neurosci.,
2004
Aug
, 20 (956-64).
657
Fodstad H
et al.
Loss-of-function mutations of the K(+) channel gene KCNJ2 constitute a rare cause of long QT syndrome.
J. Mol. Cell. Cardiol.,
2004
Aug
, 37 (593-602).
658
Leonoudakis D
et al.
A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.
J. Biol. Chem.,
2004
Apr
30
, 279 (19051-63).
659
Ivanina T
et al.
Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.
J. Biol. Chem.,
2004
Apr
23
, 279 (17260-8).
660
Ishihara K
et al.
Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line.
J. Physiol. (Lond.),
2004
Apr
1
, 556 (61-78).
661
Sackin H
et al.
Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels.
Biophys. J.,
2004
Apr
, 86 (2145-55).
662
Dahlmann A
et al.
Regulation of Kir channels by intracellular pH and extracellular K(+): mechanisms of coupling.
J. Gen. Physiol.,
2004
Apr
, 123 (441-54).
663
Ricardo Pérez Riera A
et al.
Andersen syndrome: the newest variant of the hereditary-familial long QT syndrome.
Ann Noninvasive Electrocardiol,
2004
Apr
, 9 (175-9).
664
Charpentier F
et al.
Cardiac channelopathies: from men to mice.
Ann. Med.,
2004
, 36 Suppl 1 (28-34).
665
Donaldson MR
et al.
Andersen-Tawil syndrome: a model of clinical variability, pleiotropy, and genetic heterogeneity.
Ann. Med.,
2004
, 36 Suppl 1 (92-7).
666
Sampson LJ
et al.
Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1.
J. Biol. Chem.,
2003
Oct
24
, 278 (41988-97).
667
Wolff C
et al.
Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays.
,
2003
Oct
, 8 (533-43).
668
Jones SV
Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1.
Mol. Pharmacol.,
2003
Oct
, 64 (987-93).
669
Vicente R
et al.
Differential voltage-dependent K+ channel responses during proliferation and activation in macrophages.
J. Biol. Chem.,
2003
Nov
21
, 278 (46307-20).
670
Chang HK
et al.
The effects of spermine on the accessibility of residues in the M2 segment of Kir2.1 channels expressed in Xenopus oocytes.
J. Physiol. (Lond.),
2003
Nov
15
, 553 (101-12).
671
Zhao Q
et al.
Interaction of G protein beta subunit with inward rectifier K(+) channel Kir3.
Mol. Pharmacol.,
2003
Nov
, 64 (1085-91).
672
Guo D
et al.
Interaction mechanisms between polyamines and IRK1 inward rectifier K+ channels.
J. Gen. Physiol.,
2003
Nov
, 122 (485-500).
673
Stockklausner C
et al.
Surface expression of inward rectifier potassium channels is controlled by selective Golgi export.
J. Biol. Chem.,
2003
May
9
, 278 (17000-5).
674
Miake J
et al.
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression.
J. Clin. Invest.,
2003
May
, 111 (1529-36).
675
Oz M
et al.
Effects of extracellular sodium on mu-opioid receptors coupled to potassium channels coexpressed in Xenopus oocytes.
Pflugers Arch.,
2003
Mar
, 445 (716-20).
676
Kobayashi T
et al.
Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).
Br. J. Pharmacol.,
2003
Mar
, 138 (1119-28).
677
Pil J
et al.
Serine 329 of the mu-opioid receptor interacts differently with agonists.
J. Pharmacol. Exp. Ther.,
2003
Mar
, 304 (924-30).
678
Donaldson MR
et al.
PIP2 binding residues of Kir2.1 are common targets of mutations causing Andersen syndrome.
Neurology,
2003
Jun
10
, 60 (1811-6).
679
Warren M
et al.
Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart.
J. Cardiovasc. Electrophysiol.,
2003
Jun
, 14 (621-31).
680
Karkanis T
et al.
Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery.
Am. J. Physiol. Heart Circ. Physiol.,
2003
Jun
, 284 (H2325-34).
681
Garneau L
et al.
Contribution of cytosolic cysteine residues to the gating properties of the Kir2.1 inward rectifier.
Biophys. J.,
2003
Jun
, 84 (3717-29).
682
Zobel C
et al.
Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.
J. Physiol. (Lond.),
2003
Jul
15
, 550 (365-72).
683
Tian M
et al.
Expression patterns of inwardly rectifying potassium channel subunits in rat retina.
Neurosci. Lett.,
2003
Jul
10
, 345 (9-12).
684
Xie LH
et al.
Inward rectification by polyamines in mouse Kir2.1 channels: synergy between blocking components.
J. Physiol. (Lond.),
2003
Jul
1
, 550 (67-82).
685
Rohacs T
et al.
Specificity of activation by phosphoinositides determines lipid regulation of Kir channels.
Proc. Natl. Acad. Sci. U.S.A.,
2003
Jan
21
, 100 (745-50).
686
Hommers LG
et al.
Regulation of the inward rectifying properties of G-protein-activated inwardly rectifying K+ (GIRK) channels by Gbeta gamma subunits.
J. Biol. Chem.,
2003
Jan
10
, 278 (1037-43).
687
Chang HK
et al.
Conformational changes in Kir2.1 channels during NH4+-induced inactivation.
J. Biol. Chem.,
2003
Jan
10
, 278 (908-18).
688
Takano M
et al.
Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism.
Prog. Biophys. Mol. Biol.,
2003
Jan
, 81 (67-79).
689
Mao J
et al.
Inhibition of G-protein-coupled inward rectifying K+ channels by intracellular acidosis.
J. Biol. Chem.,
2003
Feb
28
, 278 (7091-8).
690
Prüss H
et al.
Kir2 potassium channels in rat striatum are strategically localized to control basal ganglia function.
Brain Res. Mol. Brain Res.,
2003
Feb
20
, 110 (203-19).
691
Hayashi M
et al.
An inwardly rectifying K+ channel in bovine parotid acinar cells: possible involvement of Kir2.1.
J. Physiol. (Lond.),
2003
Feb
15
, 547 (255-69).
692
Müllner C
et al.
Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation.
Biophys. J.,
2003
Feb
, 84 (1399-409).
693
Ning L
et al.
Denaturing high-performance liquid chromatography quickly and reliably detects cardiac ion channel mutations in long QT syndrome.
Genet. Test.,
2003
Fall
, 7 (249-53).
694
Dibb KM
et al.
Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel.
J. Biol. Chem.,
2003
Dec
5
, 278 (49537-48).
695
Bendahhou S
et al.
Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome.
J. Biol. Chem.,
2003
Dec
19
, 278 (51779-85).
696
Oz M
et al.
Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.
Synapse,
2003
Dec
15
, 50 (303-13).
697
Ren Y
et al.
Altered mRNA expression of ATP-sensitive and inward rectifier potassium channel subunits in streptozotocin-induced diabetic rat heart and aorta.
J. Pharmacol. Sci.,
2003
Dec
, 93 (478-83).
698
Ford BD
et al.
Neuregulin-1 suppresses muscarinic receptor expression and acetylcholine-activated muscarinic K+ channels in cardiac myocytes.
Biochem. Biophys. Res. Commun.,
2003
Aug
15
, 308 (23-8).
699
Ivanina T
et al.
Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel.
J. Biol. Chem.,
2003
Aug
1
, 278 (29174-83).
700
Schram G
et al.
Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents.
Cardiovasc. Res.,
2003
Aug
1
, 59 (328-38).
701
Bosche LI
et al.
G protein-independent inhibition of GIRK current by adenosine in rat atrial myocytes overexpressing A1 receptors after adenovirus-mediated gene transfer.
J. Physiol. (Lond.),
2003
Aug
1
, 550 (707-17).
702
Lange PS
et al.
Andersen mutations of KCNJ2 suppress the native inward rectifier current IK1 in a dominant-negative fashion.
Cardiovasc. Res.,
2003
Aug
1
, 59 (321-7).
703
Hoang QV
et al.
Effects of orexin (hypocretin) on GIRK channels.
J. Neurophysiol.,
2003
Aug
, 90 (693-702).
704
Xiao J
et al.
Localization of PIP2 activation gate in inward rectifier K+ channels.
Nat. Neurosci.,
2003
Aug
, 6 (811-8).
705
Yang D
et al.
Expression of the inwardly rectifying K+ channel Kir2.1 in native bovine corneal endothelial cells.
Invest. Ophthalmol. Vis. Sci.,
2003
Aug
, 44 (3511-9).
706
Matsuda H
et al.
Voltage-dependent gating and block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1.
J. Physiol. (Lond.),
2003
Apr
15
, 548 (361-71).
707
McLerie M
et al.
Dominant-negative suppression of I(K1) in the mouse heart leads to altered cardiac excitability.
J. Mol. Cell. Cardiol.,
2003
Apr
, 35 (367-78).
708
Hosaka Y
et al.
Function, subcellular localization and assembly of a novel mutation of KCNJ2 in Andersen's syndrome.
J. Mol. Cell. Cardiol.,
2003
Apr
, 35 (409-15).
709
Konstas AA
et al.
Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels.
Am. J. Physiol., Cell Physiol.,
2003
Apr
, 284 (C910-7).
710
Guo D
et al.
Mechanism of rectification in inward-rectifier K+ channels.
J. Gen. Physiol.,
2003
Apr
, 121 (261-75).
711
Meola G
et al.
Muscle biopsy and cell cultures: potential diagnostic tools in hereditary skeletal muscle channelopathies.
Eur J Histochem,
2003
, 47 (17-28).
712
Eschke D
et al.
Identification of inwardly rectifying potassium channels in bovine retinal and choroidal endothelial cells.
Ophthalmic Res.,
2002 Nov-Dec
, 34 (343-8).
713
Kofuji P
et al.
Kir potassium channel subunit expression in retinal glial cells: implications for spatial potassium buffering.
Glia,
2002
Sep
, 39 (292-303).
714
Melnyk P
et al.
Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle.
Am. J. Physiol. Heart Circ. Physiol.,
2002
Sep
, 283 (H1123-33).
715
Andelfinger G
et al.
KCNJ2 mutation results in Andersen syndrome with sex-specific cardiac and skeletal muscle phenotypes.
Am. J. Hum. Genet.,
2002
Sep
, 71 (663-8).
716
Schwalbe RA
et al.
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Biochemistry,
2002
Oct
15
, 41 (12457-66).
717
Schram G
et al.
Kir2.4 and Kir2.1 K(+) channel subunits co-assemble: a potential new contributor to inward rectifier current heterogeneity.
J. Physiol. (Lond.),
2002
Oct
15
, 544 (337-49).
718
Guo D
et al.
IRK1 inward rectifier K(+) channels exhibit no intrinsic rectification.
J. Gen. Physiol.,
2002
Oct
, 120 (539-51).
719
Richter M
et al.
Voltage-dependent potassium channels in cytokeratin-positive and cytokeratin-negative microvascular endothelial cells of the corpus luteum.
Cell Tissue Res.,
2002
Oct
, 310 (103-8).
720
Mao J
et al.
Molecular determinants for activation of G-protein-coupled inward rectifier K+ (GIRK) channels by extracellular acidosis.
J. Biol. Chem.,
2002
Nov
29
, 277 (46166-71).
721
Murata Y
et al.
Identification of a site involved in the block by extracellular Mg(2+) and Ba(2+) as well as permeation of K(+) in the Kir2.1 K(+) channel.
J. Physiol. (Lond.),
2002
Nov
1
, 544 (665-77).
722
Fujiwara Y
et al.
Ser165 in the second transmembrane region of the Kir2.1 channel determines its susceptibility to blockade by intracellular Mg2+.
J. Gen. Physiol.,
2002
Nov
, 120 (677-93).
723
Preisig-Müller R
et al.
Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome.
Proc. Natl. Acad. Sci. U.S.A.,
2002
May
28
, 99 (7774-9).
724
Hoger JH
et al.
Shear stress regulates the endothelial Kir2.1 ion channel.
Proc. Natl. Acad. Sci. U.S.A.,
2002
May
28
, 99 (7780-5).
725
Skatchkov SN
et al.
Functional expression of Kir 6.1/SUR1-K(ATP) channels in frog retinal Müller glial cells.
Glia,
2002
May
, 38 (256-67).
726
Felix R
et al.
Identification of distinct K+ channels in mouse spermatogenic cells and sperm.
Zygote,
2002
May
, 10 (183-8).
727
Xu XH
et al.
mRNA expression alterations of inward rectifier potassium channels in rat brain with cholinergic impairment.
Neurosci. Lett.,
2002
Mar
29
, 322 (25-8).
728
Mirshahi T
et al.
Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels.
J. Biol. Chem.,
2002
Mar
1
, 277 (7348-55).
729
Schröder W
et al.
AMPA receptor-mediated modulation of inward rectifier K+ channels in astrocytes of mouse hippocampus.
Mol. Cell. Neurosci.,
2002
Mar
, 19 (447-58).
730
Oonuma H
et al.
Inward rectifier K(+) current in human bronchial smooth muscle cells: inhibition with antisense oligonucleotides targeted to Kir2.1 mRNA.
Am. J. Respir. Cell Mol. Biol.,
2002
Mar
, 26 (371-9).
731
Ai T
et al.
Novel KCNJ2 mutation in familial periodic paralysis with ventricular dysrhythmia.
Circulation,
2002
Jun
4
, 105 (2592-4).
732
Vanoye CG
et al.
The carboxyl termini of K(ATP) channels bind nucleotides.
J. Biol. Chem.,
2002
Jun
28
, 277 (23260-70).
733
Raap M
et al.
Diversity of Kir channel subunit mRNA expressed by retinal glial cells of the guinea-pig.
Neuroreport,
2002
Jun
12
, 13 (1037-40).
734
Chen L
et al.
A glutamate residue at the C terminus regulates activity of inward rectifier K+ channels: implication for Andersen's syndrome.
Proc. Natl. Acad. Sci. U.S.A.,
2002
Jun
11
, 99 (8430-5).
735
Schwalbe RA
et al.
Site-directed glycosylation tagging of functional Kir2.1 reveals that the putative pore-forming segment is extracellular.
J. Biol. Chem.,
2002
Jul
5
, 277 (24382-9).
736
Xie LH
et al.
Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block.
J. Gen. Physiol.,
2002
Jul
, 120 (53-66).
737
Sakai H
et al.
Molecular and pharmacological properties of inwardly rectifying K+ channels of human lung cancer cells.
Eur. J. Pharmacol.,
2002
Jan
25
, 435 (125-33).
738
Liu Y
et al.
Tenidap, a novel anti-inflammatory agent, is an opener of the inwardly rectifying K+ channel hKir2.3.
Eur. J. Pharmacol.,
2002
Jan
25
, 435 (153-60).
739
Manning Fox JE
et al.
Cardioselectivity of the sulphonylurea HMR 1098: studies on native and recombinant cardiac and pancreatic K(ATP) channels.
Br. J. Pharmacol.,
2002
Jan
, 135 (480-8).
740
Kobayashi T
et al.
Functional characterization of an endogenous Xenopus oocyte adenosine receptor.
Br. J. Pharmacol.,
2002
Jan
, 135 (313-22).
741
Wickman K
et al.
Structural characterization of the mouse Girk genes.
Gene,
2002
Feb
6
, 284 (241-50).
742
He C
et al.
Identification of critical residues controlling G protein-gated inwardly rectifying K(+) channel activity through interactions with the beta gamma subunits of G proteins.
J. Biol. Chem.,
2002
Feb
22
, 277 (6088-96).
743
Brochiero E
et al.
Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.
Am. J. Physiol. Renal Physiol.,
2002
Feb
, 282 (F289-300).
744
Ennis IL
et al.
Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility.
J. Clin. Invest.,
2002
Feb
, 109 (393-400).
745
Bernheim L
et al.
Human myoblast differentiation: Ca(2+) channels are activated by K(+) channels.
News Physiol. Sci.,
2002
Feb
, 17 (22-6).
746
Nishida M
et al.
Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution.
Cell,
2002
Dec
27
, 111 (957-65).
747
Guo Y
et al.
A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating.
J. Biol. Chem.,
2002
Dec
13
, 277 (48289-94).
748
Lucet V
et al.
[Andersen syndrome, ventricular arrhythmias and channelopathy (a case report)]
,
2002
Dec
, 9 (1256-9).
749
Lu Y
et al.
Contributions of Kv1.2, Kv1.5 and Kv2.1 subunits to the native delayed rectifier K(+) current in rat mesenteric artery smooth muscle cells.
Life Sci.,
2002
Aug
9
, 71 (1465-73).
750
Sadja R
et al.
Graded contribution of the Gbeta gamma binding domains to GIRK channel activation.
Proc. Natl. Acad. Sci. U.S.A.,
2002
Aug
6
, 99 (10783-8).
751
Simon J
et al.
Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells.
J. Biol. Chem.,
2002
Aug
30
, 277 (31390-400).
752
Kim HS
et al.
LB50053: a 5-hydroxytrypamine(1a) agent with a high binding affinity and a potency evoking a K(+) current.
Pharmacology,
2002
Aug
, 65 (175-81).
753
Tristani-Firouzi M
et al.
Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome).
J. Clin. Invest.,
2002
Aug
, 110 (381-8).
754
Giovannardi S
et al.
Modulation of the inward rectifier potassium channel IRK1 by the Ras signaling pathway.
J. Biol. Chem.,
2002
Apr
5
, 277 (12158-63).
755
Choi S
et al.
Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes.
Mol. Pharmacol.,
2002
Apr
, 61 (928-35).
756
Hogg DS
et al.
Endothelial cells freshly isolated from small pulmonary arteries of the rat possess multiple distinct k+ current profiles.
Lung,
2002
, 180 (203-14).
757
Jongsma HJ
et al.
Channelopathies: Kir2.1 mutations jeopardize many cell functions.
Curr. Biol.,
2001
Sep
18
, 11 (R747-50).
758
Shieh RC
et al.
Ammonium ions induce inactivation of Kir2.1 potassium channels expressed in Xenopus oocytes.
J. Physiol. (Lond.),
2001
Sep
1
, 535 (359-70).
759
Horio Y
Potassium channels of glial cells: distribution and function.
Jpn. J. Pharmacol.,
2001
Sep
, 87 (1-6).
760
Llobet A
et al.
Identification of Kir2.1 channel activity in cultured trabecular meshwork cells.
Invest. Ophthalmol. Vis. Sci.,
2001
Sep
, 42 (2371-9).
761
Picones A
et al.
Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels.
Biophys. J.,
2001
Oct
, 81 (2035-49).
762
Nilius B
et al.
Ion channels and their functional role in vascular endothelium.
Physiol. Rev.,
2001
Oct
, 81 (1415-59).
763
Pil J
et al.
The role of the hydrophilic Asn230 residue of the mu-opioid receptor in the potency of various opioid agonists.
Br. J. Pharmacol.,
2001
Oct
, 134 (496-506).
764
Jeong JS
et al.
Characterization of inwardly rectifying K(+) conductance across the basolateral membrane of rat tracheal epithelia.
Biochem. Biophys. Res. Commun.,
2001
Nov
9
, 288 (914-20).
765
Dobrev D
et al.
Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action potentials.
Circulation,
2001
Nov
20
, 104 (2551-7).
766
Suh SJ
et al.
Three functional isoforms of GAR-2, a Caenorhabditis elegans G-protein-linked acetylcholine receptor, are produced by alternative splicing.
Biochem. Biophys. Res. Commun.,
2001
Nov
16
, 288 (1238-43).
767
Choe H
et al.
Gating properties of inward-rectifier potassium channels: effects of permeant ions.
J. Membr. Biol.,
2001
Nov
1
, 184 (81-9).
768
Lu T
et al.
Permeant ion-dependent changes in gating of Kir2.1 inward rectifier potassium channels.
J. Gen. Physiol.,
2001
Nov
, 118 (509-22).
769
Zhou W
et al.
Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels.
Proc. Natl. Acad. Sci. U.S.A.,
2001
May
22
, 98 (6482-7).
770
Lei Q
et al.
Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.
J. Biol. Chem.,
2001
May
18
, 276 (16720-30).
771
Plaster NM
et al.
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome.
Cell,
2001
May
18
, 105 (511-9).
772
Fischer-Lougheed J
et al.
Human myoblast fusion requires expression of functional inward rectifier Kir2.1 channels.
J. Cell Biol.,
2001
May
14
, 153 (677-86).
773
Liu Y
et al.
Direct activation of an inwardly rectifying potassium channel by arachidonic acid.
Mol. Pharmacol.,
2001
May
, 59 (1061-8).
774
Guo D
et al.
Kinetics of inward-rectifier K+ channel block by quaternary alkylammonium ions. dimension and properties of the inner pore.
J. Gen. Physiol.,
2001
May
, 117 (395-406).
775
Komarova SV
et al.
Osteoclast ion channels: potential targets for antiresorptive drugs.
Curr. Pharm. Des.,
2001
May
, 7 (637-54).
776
Stockklausner C
et al.
A sequence motif responsible for ER export and surface expression of Kir2.0 inward rectifier K(+) channels.
FEBS Lett.,
2001
Mar
30
, 493 (129-33).
777
Tytgat J
et al.
New polypeptide components purified from mamba venom.
FEBS Lett.,
2001
Mar
2
, 491 (217-21).
778
Derst C
et al.
Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits.
FEBS Lett.,
2001
Mar
2
, 491 (305-11).
779
Kubo Y
et al.
Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel.
J. Physiol. (Lond.),
2001
Mar
15
, 531 (645-60).
780
Leonoudakis D
et al.
Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97.
J. Cell. Sci.,
2001
Mar
, 114 (987-98).
781
Firth TA
et al.
GTP-binding protein Gq mediates muscarinic-receptor-induced inhibition of the inwardly rectifying potassium channel IRK1 (Kir 2.1).
Neuropharmacology,
2001
Mar
, 40 (358-65).
782
Proks P
et al.
Interaction of stilbene disulphonates with cloned K(ATP) channels.
Br. J. Pharmacol.,
2001
Mar
, 132 (973-82).
783
Yi BA
et al.
Yeast screen for constitutively active mutant G protein-activated potassium channels.
Neuron,
2001
Mar
, 29 (657-67).
784
Dart C
et al.
Targeting of an A kinase-anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1.
J. Biol. Chem.,
2001
Jun
8
, 276 (20499-505).
785
Zaritsky JJ
et al.
The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.
J. Physiol. (Lond.),
2001
Jun
15
, 533 (697-710).
786
Paradis S
et al.
Homeostatic control of presynaptic release is triggered by postsynaptic membrane depolarization.
Neuron,
2001
Jun
, 30 (737-49).
787
Shui Z
et al.
Evidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels.
Am. J. Physiol. Heart Circ. Physiol.,
2001
Jun
, 280 (H2554-62).
788
Alagem N
et al.
Mechanism of Ba(2+) block of a mouse inwardly rectifying K+ channel: differential contribution by two discrete residues.
J. Physiol. (Lond.),
2001
Jul
15
, 534 (381-93).
789
Yamakura T
et al.
Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels.
Anesthesiology,
2001
Jul
, 95 (144-53).
790
Gregerson KA
et al.
Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland.
Endocrinology,
2001
Jul
, 142 (2820-32).
791
Tong XY
et al.
[The expression levels of GIRK1 and IRK1 in memory deficit rats]
Yao Xue Xue Bao,
2001
Jul
, 36 (485-8).
792
Stringer BK
et al.
Overexpression of the G-protein inwardly rectifying potassium channel 1 (GIRK1) in primary breast carcinomas correlates with axillary lymph node metastasis.
Cancer Res.,
2001
Jan
15
, 61 (582-8).
793
Soom M
et al.
Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels.
FEBS Lett.,
2001
Feb
9
, 490 (49-53).
794
Hill JJ
et al.
Inhibition of a Gi-activated potassium channel (GIRK1/4) by the Gq-coupled m1 muscarinic acetylcholine receptor.
J. Biol. Chem.,
2001
Feb
23
, 276 (5505-10).
795
So I
et al.
The K+ channel signature sequence of murine Kir2.1: mutations that affect microscopic gating but not ionic selectivity.
J. Physiol. (Lond.),
2001
Feb
15
, 531 (37-50).
796
Sackin H
et al.
Regulation of ROMK by extracellular cations.
Biophys. J.,
2001
Feb
, 80 (683-97).
797
Zhu L
et al.
Cloning and characterization of G protein-gated inward rectifier K+ channel (GIRK1) isoforms from heart and brain.
J. Mol. Neurosci.,
2001
Feb
, 16 (21-32).
798
Tong Y
et al.
Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel.
J. Gen. Physiol.,
2001
Feb
, 117 (103-18).
799
Slesinger PA
Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels.
Biophys. J.,
2001
Feb
, 80 (707-18).
800
Blake BL
et al.
G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13).
J. Biol. Chem.,
2001
Dec
28
, 276 (49267-74).
801
Clark RB
et al.
T-tubule localization of the inward-rectifier K(+) channel in mouse ventricular myocytes: a role in K(+) accumulation.
J. Physiol. (Lond.),
2001
Dec
15
, 537 (979-92).
802
Ruiz-Velasco V
et al.
Functional expression and FRET analysis of green fluorescent proteins fused to G-protein subunits in rat sympathetic neurons.
J. Physiol. (Lond.),
2001
Dec
15
, 537 (679-92).
803
Bender K
et al.
Overexpression of monomeric and multimeric GIRK4 subunits in rat atrial myocytes removes fast desensitization and reduces inward rectification of muscarinic K(+) current (I(K(ACh))). Evidence for functional homomeric GIRK4 channels.
J. Biol. Chem.,
2001
Aug
3
, 276 (28873-80).
804
Weigl LG
et al.
G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics.
Mol. Pharmacol.,
2001
Aug
, 60 (282-9).
805
Li JH
et al.
The expression of G-protein-gated inwardly rectifying K+ channels GIRK1 and GIRK2 mRNAs in the supraoptic nucleus of the rat and possible role involved.
Neuroreport,
2001
Apr
17
, 12 (1007-10).
806
Liu GX
et al.
Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes.
J. Physiol. (Lond.),
2001
Apr
1
, 532 (115-26).
807
Clarson LH
et al.
Inwardly rectifying K(+) current and differentiation of human placental cytotrophoblast cells in culture.
Placenta,
2001
Apr
, 22 (328-36).
808
Hardie RC
et al.
Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors.
Neuron,
2001
Apr
, 30 (149-59).
809
Murata Y
et al.
Primary structure, developmental expression and functional properties of an inward rectifier K+ channel of the tunicate.
Recept. Channels,
2001
, 7 (387-99).
810
Ulens C
et al.
Changes in GIRK1/GIRK2 deactivation kinetics and basal activity in the presence and absence of RGS4.
Life Sci.,
2000
Sep
29
, 67 (2305-17).
811
Pabon A
et al.
Glycosylation of GIRK1 at Asn119 and ROMK1 at Asn117 has different consequences in potassium channel function.
J. Biol. Chem.,
2000
Sep
29
, 275 (30677-82).
812
Medina I
et al.
A switch mechanism for G beta gamma activation of I(KACh).
J. Biol. Chem.,
2000
Sep
22
, 275 (29709-16).
813
Leung YM
et al.
Block of inwardly rectifying K+ currents by extracellular Mg2+ and Ba2+ in bovine pulmonary artery endothelial cells.
Can. J. Physiol. Pharmacol.,
2000
Sep
, 78 (751-6).
814
Dibb KM
et al.
Cs+ block of the cardiac muscarinic K+ channel, GIRK1/GIRK4, is not dependent on the aspartate residue at position 173.
Pflugers Arch.,
2000
Sep
, 440 (740-4).
815
Ulens C
et al.
Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity.
J. Pharmacol. Exp. Ther.,
2000
Sep
, 294 (1024-33).
816
Yang D
et al.
Molecular cloning and expression of an inwardly rectifying K(+) channel from bovine corneal endothelial cells.
Invest. Ophthalmol. Vis. Sci.,
2000
Sep
, 41 (2936-44).
817
Mark MD
et al.
G-protein mediated gating of inward-rectifier K+ channels.
Eur. J. Biochem.,
2000
Oct
, 267 (5830-6).
818
Schilling T
et al.
Upregulation of Kv1.3 K(+) channels in microglia deactivated by TGF-beta.
Am. J. Physiol., Cell Physiol.,
2000
Oct
, 279 (C1123-34).
819
Guo D
et al.
Pore block versus intrinsic gating in the mechanism of inward rectification in strongly rectifying IRK1 channels.
J. Gen. Physiol.,
2000
Oct
, 116 (561-8).
820
Jelacic TM
et al.
Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3.
J. Biol. Chem.,
2000
Nov
17
, 275 (36211-6).
821
Lancaster MK
et al.
Residues and mechanisms for slow activation and Ba2+ block of the cardiac muscarinic K+ channel, Kir3.1/Kir3.4.
J. Biol. Chem.,
2000
Nov
17
, 275 (35831-9).
822
Lee YS
et al.
Characterization of GAR-2, a novel G protein-linked acetylcholine receptor from Caenorhabditis elegans.
J. Neurochem.,
2000
Nov
, 75 (1800-9).
823
Bard J
et al.
Single channel studies of inward rectifier potassium channel regulation by muscarinic acetylcholine receptors.
J. Gen. Physiol.,
2000
Nov
, 116 (645-52).
824
Xie A
et al.
[The blocking effects of extracellular Mn2+ on the inward rectifier potassium channel (IRK1)]
Zhongguo Ying Yong Sheng Li Xue Za Zhi,
2000
Nov
, 16 (331-4).
825
Yakubovich D
et al.
Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes.
J. Physiol. (Lond.),
2000
May
1
, 524 Pt 3 (737-55).
826
Müllner C
et al.
Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase.
J. Gen. Physiol.,
2000
May
, 115 (547-58).
827
Kim D
et al.
Cytoplasmic unsaturated free fatty acids inhibit ATP-dependent gating of the G protein-gated K(+) channel.
J. Gen. Physiol.,
2000
Mar
, 115 (287-304).
828
Guo D
et al.
Mechanism of IRK1 channel block by intracellular polyamines.
J. Gen. Physiol.,
2000
Jun
, 115 (799-814).
829
Zaritsky JJ
et al.
Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.
Circ. Res.,
2000
Jul
21
, 87 (160-6).
830
Sobey CG
et al.
Knockout blow for channel identity crisis : vasodilation to potassium is mediated via Kir2.1.
Circ. Res.,
2000
Jul
21
, 87 (83-4).
831
Shieh RC
Mechanisms for the time-dependent decay of inward currents through cloned Kir2.1 channels expressed in Xenopus oocytes.
J. Physiol. (Lond.),
2000
Jul
15
, 526 Pt 2 (241-52).
832
Thompson GA
et al.
Residues beyond the selectivity filter of the K+ channel kir2.1 regulate permeation and block by external Rb+ and Cs+.
J. Physiol. (Lond.),
2000
Jul
15
, 526 Pt 2 (231-40).
833
Hough E
et al.
Identification of molecular regions responsible for the membrane trafficking of Kir6.2.
Pflugers Arch.,
2000
Jul
, 440 (481-7).
834
Bloms-Funke P
et al.
Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor.
Peptides,
2000
Jul
, 21 (1141-6).
835
Ivanina T
et al.
Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without beta1 integrins.
FEBS Lett.,
2000
Jan
28
, 466 (327-32).
836
Nehring RB
et al.
Neuronal inwardly rectifying K(+) channels differentially couple to PDZ proteins of the PSD-95/SAP90 family.
J. Neurosci.,
2000
Jan
1
, 20 (156-62).
837
Hallmann K
et al.
Mutation analysis of the inwardly rectifying K(+) channels KCNJ6 (GIRK2) and KCNJ3 (GIRK1) in juvenile myoclonic epilepsy.
Am. J. Med. Genet.,
2000
Feb
7
, 96 (8-11).
838
Rae JL
et al.
Kir2.1 Potassium channels and corneal epithelia.
Curr. Eye Res.,
2000
Feb
, 20 (144-52).
839
Xie A
et al.
[Blocking effects of extracellular Ba(2+) on the inward rectifier potassium channel]
,
2000
Feb
, 52 (50-4).
840
Lohberger B
et al.
IK.ACh activation by arachidonic acid occurs via a G-protein-independent pathway mediated by the GIRK1 subunit.
Pflugers Arch.,
2000
Dec
, 441 (251-6).
841
Kim SJ
et al.
Inwardly rectifying K+ channels in the basolateral membrane of rat pancreatic acini.
Pflugers Arch.,
2000
Dec
, 441 (331-40).
842
Chrissobolis S
et al.
Role of inwardly rectifying K(+) channels in K(+)-induced cerebral vasodilatation in vivo.
Am. J. Physiol. Heart Circ. Physiol.,
2000
Dec
, 279 (H2704-12).
843
Gögelein H
et al.
Inhibition of IKs channels by HMR 1556.
Naunyn Schmiedebergs Arch. Pharmacol.,
2000
Dec
, 362 (480-8).
844
Lei Q
et al.
Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits.
Proc. Natl. Acad. Sci. U.S.A.,
2000
Aug
15
, 97 (9771-6).
845
Keren-Raifman T
et al.
Expression cloning of KCRF, a potassium channel regulatory factor.
Biochem. Biophys. Res. Commun.,
2000
Aug
11
, 274 (852-8).
846
Wickman K
et al.
Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4.
J. Neurosci.,
2000
Aug
1
, 20 (5608-15).
847
Cho HC
et al.
Two critical cysteine residues implicated in disulfide bond formation and proper folding of Kir2.1.
Biochemistry,
2000
Apr
25
, 39 (4649-57).
848
Wang H
et al.
Direct block of inward rectifier potassium channels by nicotine.
Toxicol. Appl. Pharmacol.,
2000
Apr
1
, 164 (97-101).
849
Zhu G
et al.
CO(2) inhibits specific inward rectifier K(+) channels by decreases in intra- and extracellular pH.
J. Cell. Physiol.,
2000
Apr
, 183 (53-64).
850
Choe H
et al.
Permeation properties of inward-rectifier potassium channels and their molecular determinants.
J. Gen. Physiol.,
2000
Apr
, 115 (391-404).
851
Kobayashi T
et al.
Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes.
Br. J. Pharmacol.,
2000
Apr
, 129 (1716-22).
852
Jin W
et al.
Mechanisms of inward-rectifier K+ channel inhibition by tertiapin-Q.
Biochemistry,
1999
Oct
26
, 38 (14294-301).
853
Jin W
et al.
Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels.
Biochemistry,
1999
Oct
26
, 38 (14286-93).
854
Liss B
et al.
The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels.
J. Neurosci.,
1999
Oct
15
, 19 (8839-48).
855
Hou P
et al.
The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype.
J. Neurosci.,
1999
Oct
1
, 19 (8327-36).
856
Barrett-Jolley R
et al.
Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine.
Br. J. Pharmacol.,
1999
Oct
, 128 (760-6).
857
Tucker SJ
et al.
Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
J. Biol. Chem.,
1999
Nov
19
, 274 (33393-7).
858
Ho IH
et al.
Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels.
J. Physiol. (Lond.),
1999
Nov
1
, 520 Pt 3 (645-51).
859
McAllister SD
et al.
Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system.
J. Pharmacol. Exp. Ther.,
1999
Nov
, 291 (618-26).
860
Leyland ML
et al.
The possible role of a disulphide bond in forming functional Kir2.1 potassium channels.
Pflugers Arch.,
1999
Nov
, 438 (778-81).
861
Jelacic TM
et al.
Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3.
J. Membr. Biol.,
1999
May
15
, 169 (123-9).
862
Qu Z
et al.
Identification of a critical motif responsible for gating of Kir2.3 channel by intracellular protons.
J. Biol. Chem.,
1999
May
14
, 274 (13783-9).
863
Pei Q
et al.
Alteration in expression of G-protein-activated inward rectifier K+-channel subunits GIRK1 and GIRK2 in the rat brain following electroconvulsive shock.
Neuroscience,
1999
May
, 90 (621-7).
864
Owen JM
et al.
Effect of extracellular cations on the inward rectifying K+ channels Kir2.1 and Kir3.1/Kir3.4.
Exp. Physiol.,
1999
May
, 84 (471-88).
865
Otero AS
et al.
Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current.
Biochim. Biophys. Acta,
1999
Mar
8
, 1449 (157-68).
866
Ho IH
et al.
Molecular determinants for sodium-dependent activation of G protein-gated K+ channels.
J. Biol. Chem.,
1999
Mar
26
, 274 (8639-48).
867
Fernández-Fernández JM
et al.
Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones.
J. Physiol. (Lond.),
1999
Mar
15
, 515 ( Pt 3) (631-7).
868
Bradley KK
et al.
Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells.
J. Physiol. (Lond.),
1999
Mar
15
, 515 ( Pt 3) (639-51).
869
Tonini R
et al.
Expression of Ras-GRF in the SK-N-BE neuroblastoma accelerates retinoic-acid-induced neuronal differentiation and increases the functional expression of the IRK1 potassium channel.
Eur. J. Neurosci.,
1999
Mar
, 11 (959-66).
870
Lu T
et al.
Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification.
Neuron,
1999
Mar
, 22 (571-80).
871
Shieh RC
et al.
K+ binding sites and interactions between permeating K+ ions at the external pore mouth of an inward rectifier K+ channel (Kir2.1).
J. Biol. Chem.,
1999
Jun
18
, 274 (17424-30).
872
Herlitze S
et al.
New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes.
J. Physiol. (Lond.),
1999
Jun
1
, 517 ( Pt 2) (341-52).
873
Raymond V
et al.
DmGluRA, a Drosophila metabotropic glutamate receptor, activates G-protein inwardly rectifying potassium channels in Xenopus oocytes.
Neurosci. Lett.,
1999
Jul
2
, 269 (1-4).
874
Flynn ER
et al.
Inward rectifier potassium conductance regulates membrane potential of canine colonic smooth muscle.
J. Physiol. (Lond.),
1999
Jul
1
, 518 ( Pt 1) (247-56).
875
Zhang H
et al.
Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions.
Nat. Cell Biol.,
1999
Jul
, 1 (183-8).
876
Kennedy ME
et al.
GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels.
J. Biol. Chem.,
1999
Jan
22
, 274 (2571-82).
877
Klein H
et al.
Molecular characterization of an inwardly rectifying K+ channel from HeLa cells.
J. Membr. Biol.,
1999
Jan
1
, 167 (43-52).
878
Lee YS
et al.
Cloning and expression of a G protein-linked acetylcholine receptor from Caenorhabditis elegans.
J. Neurochem.,
1999
Jan
, 72 (58-65).
879
Pearson WL
et al.
Expression of a functional Kir4 family inward rectifier K+ channel from a gene cloned from mouse liver.
J. Physiol. (Lond.),
1999
Feb
1
, 514 ( Pt 3) (639-53).
880
Jeglitsch G
et al.
The cardiac acetylcholine-activated, inwardly rectifying K+-channel subunit GIRK1 gives rise to an inward current induced by free oxygen radicals.
Free Radic. Biol. Med.,
1999
Feb
, 26 (253-9).
881
Ulens C
et al.
The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands.
Eur. J. Pharmacol.,
1999
Dec
3
, 385 (239-45).
882
Kawano T
et al.
Importance of the G protein gamma subunit in activating G protein-coupled inward rectifier K(+) channels.
FEBS Lett.,
1999
Dec
17
, 463 (355-9).
883
Rohács T
et al.
Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides.
J. Biol. Chem.,
1999
Dec
17
, 274 (36065-72).
884
Lewohl JM
et al.
G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action.
Nat. Neurosci.,
1999
Dec
, 2 (1084-90).
885
Kobayashi T
et al.
Ethanol opens G-protein-activated inwardly rectifying K+ channels.
Nat. Neurosci.,
1999
Dec
, 2 (1091-7).
886
Stonehouse AH
et al.
Characterisation of Kir2.0 proteins in the rat cerebellum and hippocampus by polyclonal antibodies.
Histochem. Cell Biol.,
1999
Dec
, 112 (457-65).
887
Muma NA
et al.
Corticosteroids alter G protein inwardly rectifying potassium channels protein levels in hippocampal subfields.
Brain Res.,
1999
Aug
28
, 839 (331-5).
888
Lu T
et al.
Cytoplasmic amino and carboxyl domains form a wide intracellular vestibule in an inwardly rectifying potassium channel.
Proc. Natl. Acad. Sci. U.S.A.,
1999
Aug
17
, 96 (9926-31).
889
Nakamura TY
et al.
The role of Kir2.1 in the genesis of native cardiac inward-rectifier K+ currents during pre- and postnatal development.
Ann. N. Y. Acad. Sci.,
1999
Apr
30
, 868 (434-7).
890
Dart C
et al.
Topology of the pore region of an inward rectifier K+ channel, Kir2.1.
Ann. N. Y. Acad. Sci.,
1999
Apr
30
, 868 (414-7).
891
He C
et al.
Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling.
J. Biol. Chem.,
1999
Apr
30
, 274 (12517-24).
892
Zhu G
et al.
Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53.
J. Biol. Chem.,
1999
Apr
23
, 274 (11643-6).
893
Saitoh O
et al.
RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents.
J. Biol. Chem.,
1999
Apr
2
, 274 (9899-904).
894
Yue L
et al.
Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation.
Circ. Res.,
1999
Apr
16
, 84 (776-84).
895
Holt JR
et al.
Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors.
J. Neurophysiol.,
1999
Apr
, 81 (1881-8).
896
Choe H
et al.
Structural determinants of gating in inward-rectifier K+ channels.
Biophys. J.,
1999
Apr
, 76 (1988-2003).
897
Lee JK
et al.
Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1.
J. Gen. Physiol.,
1999
Apr
, 113 (555-64).
898
Waldegger S
et al.
Effect of verapamil enantiomers and metabolites on cardiac K+ channels expressed in Xenopus oocytes.
Cell. Physiol. Biochem.,
1999
, 9 (81-9).
899
Ho BY
et al.
Coupling of the expressed cannabinoid CB1 and CB2 receptors to phospholipase C and G protein-coupled inwardly rectifying K+ channels.
Recept. Channels,
1999
, 6 (363-74).
900
Smith KE
et al.
Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels.
J. Biol. Chem.,
1998
Sep
4
, 273 (23321-6).
901
Jin W
et al.
A novel high-affinity inhibitor for inward-rectifier K+ channels.
Biochemistry,
1998
Sep
22
, 37 (13291-9).
902
Kubo Y
et al.
Probing pore topology and conformational changes of Kir2.1 potassium channels by cysteine scanning mutagenesis.
FEBS Lett.,
1998
Sep
11
, 435 (69-73).
903
Mermelstein PG
et al.
Inwardly rectifying potassium (IRK) currents are correlated with IRK subunit expression in rat nucleus accumbens medium spiny neurons.
J. Neurosci.,
1998
Sep
1
, 18 (6650-61).
904
Silverman SK
et al.
Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel.
Biophys. J.,
1998
Sep
, 75 (1330-9).
905
Pearson WL
et al.
Block of the Kir2.1 channel pore by alkylamine analogues of endogenous polyamines.
J. Gen. Physiol.,
1998
Sep
, 112 (351-63).
906
Kääb S
et al.
Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density.
Circulation,
1998
Oct
6
, 98 (1383-93).
907
Corey S
et al.
Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers.
J. Biol. Chem.,
1998
Oct
16
, 273 (27499-504).
908
Stampe P
et al.
Nonindependent K+ movement through the pore in IRK1 potassium channels.
J. Gen. Physiol.,
1998
Oct
, 112 (475-84).
909
Mylona P
et al.
Detection of a high-frequency silent polymorphism (C-->T) in the kir2.1 (KCNJ2) inwardly rectifying potassium channel gene by polymerase chain reaction and single strand conformation polymorphism.
Mol. Cell. Probes,
1998
Oct
, 12 (331-3).
910
Shieh RC
et al.
Interaction of Ba2+ with the pores of the cloned inward rectifier K+ channels Kir2.1 expressed in Xenopus oocytes.
Biophys. J.,
1998
Nov
, 75 (2313-22).
911
Lopatin AN
et al.
A novel crystallization method for visualizing the membrane localization of potassium channels.
Biophys. J.,
1998
May
, 74 (2159-70).
912
Uezono Y
et al.
Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes.
Neuroreport,
1998
Mar
9
, 9 (583-7).
913
Arcangeli A
et al.
Long-term exposure to retinoic acid induces the expression of IRK1 channels in HERG channel-endowed neuroblastoma cells.
Biochem. Biophys. Res. Commun.,
1998
Mar
27
, 244 (706-11).
914
Nakamura TY
et al.
Inhibition of rat ventricular IK1 with antisense oligonucleotides targeted to Kir2.1 mRNA.
Am. J. Physiol.,
1998
Mar
, 274 (H892-900).
915
Rae JL
et al.
Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family.
Exp. Eye Res.,
1998
Mar
, 66 (347-59).
916
Töpert C
et al.
Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei.
J. Neurosci.,
1998
Jun
1
, 18 (4096-105).
917
Raab-Graham KF
et al.
Tetrameric subunit structure of the native brain inwardly rectifying potassium channel Kir 2.2.
J. Biol. Chem.,
1998
Jul
31
, 273 (19699-707).
918
Krapivinsky G
et al.
Gbeta binding to GIRK4 subunit is critical for G protein-gated K+ channel activation.
J. Biol. Chem.,
1998
Jul
3
, 273 (16946-52).
919
Luchian T
et al.
Ion permeation through a G-protein activated (GIRK1/GIRK5) inwardly rectifying potassium channel.
Biochim. Biophys. Acta,
1998
Jan
19
, 1368 (167-70).
920
Tare M
et al.
Inwardly rectifying whole cell potassium current in human blood eosinophils.
J. Physiol. (Lond.),
1998
Jan
15
, 506 ( Pt 2) (303-18).
921
Chen H
et al.
Cyclosporin A selectively reduces the functional expression of Kir2.1 potassium channels in Xenopus oocytes.
FEBS Lett.,
1998
Feb
6
, 422 (307-10).
922
Corey S
et al.
Number and stoichiometry of subunits in the native atrial G-protein-gated K+ channel, IKACh.
J. Biol. Chem.,
1998
Feb
27
, 273 (5271-8).
923
Huang CL
et al.
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma.
Nature,
1998
Feb
19
, 391 (803-6).
924
Mylona P
et al.
Expression of the Kir2.1 (inwardly rectifying potassium channel) gene in the human placenta and in cultured cytotrophoblast cells at different stages of differentiation.
Mol. Hum. Reprod.,
1998
Feb
, 4 (195-200).
925
Sun L
et al.
Regulation of K+ and Ca++ channels by a family of neuropeptide Y receptors.
J. Pharmacol. Exp. Ther.,
1998
Feb
, 284 (625-32).
926
Kobayashi T
et al.
Effects of clozapine on the delta- and kappa-opioid receptors and the G-protein-activated K+ (GIRK) channel expressed in Xenopus oocytes.
Br. J. Pharmacol.,
1998
Feb
, 123 (421-6).
927
Wischmeyer E
et al.
Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation.
J. Biol. Chem.,
1998
Dec
18
, 273 (34063-8).
928
Ruiz-Velasco V
et al.
Heterologous expression and coupling of G protein-gated inwardly rectifying K+ channels in adult rat sympathetic neurons.
J. Physiol. (Lond.),
1998
Dec
15
, 513 ( Pt 3) (761-73).
929
Wang Z
et al.
Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle.
Circulation,
1998
Dec
1
, 98 (2422-8).
930
Standen NB
et al.
K+ channel modulation in arterial smooth muscle.
Acta Physiol. Scand.,
1998
Dec
, 164 (549-57).
931
Redell JB
et al.
Multiple promoter elements interact to control the transcription of the potassium channel gene, KCNJ2.
J. Biol. Chem.,
1998
Aug
28
, 273 (22807-18).
932
Dart C
et al.
The selectivity filter of a potassium channel, murine kir2.1, investigated using scanning cysteine mutagenesis.
J. Physiol. (Lond.),
1998
Aug
15
, 511 ( Pt 1) (25-32).
933
Dart C
et al.
The dependence of Ag+ block of a potassium channel, murine kir2.1, on a cysteine residue in the selectivity filter.
J. Physiol. (Lond.),
1998
Aug
15
, 511 ( Pt 1) (15-24).
934
Oishi K
et al.
Neutralization of aspartate residues in the murine inwardly rectifying K+ channel IRK1 affects the substate behaviour in Mg2+ block.
J. Physiol. (Lond.),
1998
Aug
1
, 510 ( Pt 3) (675-83).
935
Ivanova-Nikolova TT
et al.
Muscarinic K+ channel in the heart. Modal regulation by G protein beta gamma subunits.
J. Gen. Physiol.,
1998
Aug
, 112 (199-210).
936
Pillai G
et al.
Human D2 and D4 dopamine receptors couple through betagamma G-protein subunits to inwardly rectifying K+ channels (GIRK1) in a Xenopus oocyte expression system: selective antagonism by L-741,626 and L-745,870 respectively.
Neuropharmacology,
1998
Aug
, 37 (983-7).
937
Nilius B
Signaltransduction in vascular endothelium: the role of intracellular calcium and ion channels.
Verh. K. Acad. Geneeskd. Belg.,
1998
, 60 (215-50).
938
Guo L
et al.
Comparison of the open-close kinetics of the cloned inward rectifier K+ channel IRK1 and its point mutant (Q140E) in the pore region.
Recept. Channels,
1998
, 5 (273-89).
939
Höllerer-Beitz G
et al.
Influence of detergents on the function of cloned potassium channels.
Recept. Channels,
1998
, 5 (61-78).
940
Suessbrich H
et al.
Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241.
FEBS Lett.,
1997
Sep
8
, 414 (435-8).
941
Kovoor A
et al.
Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes.
J. Biol. Chem.,
1997
Oct
31
, 272 (27605-11).
942
Slesinger PA
et al.
Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Oct
28
, 94 (12210-7).
943
Taglialatela M
et al.
Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Oct
14
, 94 (11698-703).
944
Thomas SL
et al.
Tissue-specific regulation of G-protein-coupled inwardly rectifying K+ channel expression by muscarinic receptor activation in ovo.
J. Biol. Chem.,
1997
Nov
21
, 272 (29958-62).
945
Luchian T
et al.
A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes.
J. Physiol. (Lond.),
1997
Nov
15
, 505 ( Pt 1) (13-22).
946
Kamouchi M
et al.
Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells.
J. Physiol. (Lond.),
1997
Nov
1
, 504 ( Pt 3) (545-56).
947
Collins A
et al.
Scanning mutagenesis of the putative transmembrane segments of Kir2.1, an inward rectifier potassium channel.
Proc. Natl. Acad. Sci. U.S.A.,
1997
May
13
, 94 (5456-60).
948
Miyashita T
et al.
Localization and developmental changes of the expression of two inward rectifying K(+)-channel proteins in the rat brain.
Brain Res.,
1997
Mar
7
, 750 (251-63).
949
Chan KW
et al.
Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity.
J. Biol. Chem.,
1997
Mar
7
, 272 (6548-55).
950
Wickman K
et al.
Partial structure, chromosome localization, and expression of the mouse Girk4 gene.
Genomics,
1997
Mar
15
, 40 (395-401).
951
Omori K
et al.
Inwardly rectifying potassium channels expressed by gene transfection into the green Monkey kidney cell line COS-1.
J. Physiol. (Lond.),
1997
Mar
1
, 499 ( Pt 2) (369-78).
952
Kobayashi T
et al.
Effects of sigma ligands on the nociceptin/orphanin FQ receptor co-expressed with the G-protein-activated K+ channel in Xenopus oocytes.
Br. J. Pharmacol.,
1997
Mar
, 120 (986-7).
953
Suessbrich H
et al.
The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes.
Br. J. Pharmacol.,
1997
Mar
, 120 (968-74).
954
Forsyth SE
et al.
Molecular cloning and expression of a bovine endothelial inward rectifier potassium channel.
FEBS Lett.,
1997
Jun
9
, 409 (277-82).
955
Chuang H
et al.
Regulation of IRK3 inward rectifier K+ channel by m1 acetylcholine receptor and intracellular magnesium.
Cell,
1997
Jun
27
, 89 (1121-32).
956
Ehrengruber MU
et al.
Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Jun
24
, 94 (7070-5).
957
Nelson CS
et al.
Cloning and characterization of Kir3.1 (GIRK1) C-terminal alternative splice variants.
Brain Res. Mol. Brain Res.,
1997
Jun
, 46 (185-96).
958
Darlison MG
et al.
Opioid receptors from a lower vertebrate (Catostomus commersoni): sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Jul
22
, 94 (8214-9).
959
Yan K
et al.
Structural determinants for interaction with three different effectors on the G protein beta subunit.
J. Biol. Chem.,
1997
Jan
24
, 272 (2056-9).
960
Gribble FM
et al.
Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.
J. Physiol. (Lond.),
1997
Jan
1
, 498 ( Pt 1) (87-98).
961
Kim D
et al.
ATP-dependent regulation of a G protein-coupled K+ channel (GIRK1/GIRK4) expressed in oocytes.
Am. J. Physiol.,
1997
Jan
, 272 (H195-206).
962
Monaghan AS
et al.
Inwardly rectifying K+ currents of alveolar type II cells isolated from fetal guinea-pig lung: regulation by G protein- and Mg2+-dependent pathways.
Pflugers Arch.,
1997
Jan
, 433 (294-303).
963
Drake CT
et al.
GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Feb
4
, 94 (1007-12).
964
Signorini S
et al.
Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Feb
4
, 94 (923-7).
965
Yang J
et al.
Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel.
Proc. Natl. Acad. Sci. U.S.A.,
1997
Feb
18
, 94 (1568-72).
966
Schoots O
et al.
Genomic organization and promoter analysis of the human G-protein-coupled K+ channel Kir3.1 (KCNJ3/HGIRK1).
Genomics,
1997
Feb
1
, 39 (279-88).
967
Isomoto S
et al.
Inwardly rectifying potassium channels: their molecular heterogeneity and function.
Jpn. J. Physiol.,
1997
Feb
, 47 (11-39).
968
Sabirov RZ
et al.
Two-sided action of protons on an inward rectifier K+ channel (IRK1).
Pflugers Arch.,
1997
Feb
, 433 (428-34).
969
Jones SV
Dual modulation of an inwardly rectifying potassium conductance.
Neuropharmacology,
1997
Feb
, 36 (209-15).
970
Ishihara K
Time-dependent outward currents through the inward rectifier potassium channel IRK1. The role of weak blocking molecules.
J. Gen. Physiol.,
1997
Feb
, 109 (229-43).
971
Kreienkamp HJ
et al.
Coupling of rat somatostatin receptor subtypes to a G-protein gated inwardly rectifying potassium channel (GIRK1).
FEBS Lett.,
1997
Dec
8
, 419 (92-4).
972
Chen SC
et al.
Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse.
Brain Res.,
1997
Dec
19
, 778 (251-64).
973
Gadbut AP
et al.
Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteins.
EMBO J.,
1997
Dec
15
, 16 (7250-60).
974
Vivaudou M
et al.
Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.
J. Biol. Chem.,
1997
Dec
12
, 272 (31553-60).
975
Sabirov RZ
et al.
A conserved arginine residue in the pore region of an inward rectifier K channel (IRK1) as an external barrier for cationic blockers.
J. Gen. Physiol.,
1997
Dec
, 110 (665-77).
976
Shin KS
et al.
Opposite effect of intracellular Ca2+ and protein kinase C on the expression of inwardly rectifying K+ channel 1 in mouse skeletal muscle.
J. Biol. Chem.,
1997
Aug
22
, 272 (21227-32).
977
Huang CL
et al.
Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels.
FEBS Lett.,
1997
Apr
1
, 405 (291-8).
978
Ikeda K
et al.
Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel.
Brain Res. Mol. Brain Res.,
1997
Apr
, 45 (117-26).
979
Sharon D
et al.
Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes.
J. Gen. Physiol.,
1997
Apr
, 109 (477-90).
980
McKinnon LA
et al.
Regulation of muscarinic receptor expression and function in cultured cells and in knock-out mice.
Life Sci.,
1997
, 60 (1101-4).