TRPC

1

Wang Q et al. Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.
Am. J. Physiol., Cell Physiol., 2016 May 4 , (ajpcell.00092.2016).

2

Zhu Y et al. Zeranol induces COX-2 expression through TRPC-3 activation in the placental cells JEG-3.
Toxicol In Vitro, 2016 May 17 , 35 (17-23).

3

Molnar T et al. Store-Operated Calcium Entry in Müller Glia Is Controlled by Synergistic Activation of TRPC and Orai Channels.
J. Neurosci., 2016 Mar 16 , 36 (3184-98).

4

Perrouin Verbe MA et al. Expression of store-operated channel components in prostate cancer: the prognostic paradox.
Hum. Pathol., 2016 Mar , 49 (77-82).

5

Sawamura S et al. Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.
Mol. Pharmacol., 2016 Mar , 89 (348-63).

6

Gaunt HJ et al. Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics.
Eur. Biophys. J., 2016 Jun 11 , ().

7

Yao XM et al. Astragaloside IV prevents high glucose-induced podocyte apoptosis via downregulation of TRPC6.
Mol Med Rep, 2016 Jun , 13 (5149-56).

8

Gavello D et al. Leptin-mediated ion channel regulation: PI3K pathways, physiological role, and therapeutic potential.
Channels (Austin), 2016 Jul 3 , 10 (282-96).

9

Thakur DP et al. Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels.
Proc. Natl. Acad. Sci. U.S.A., 2016 Jan 26 , 113 (1092-7).

10

Numaga-Tomita T et al. TRPC3 amplifies B-cell receptor-induced ERK signalling via protein kinase D-dependent Rap1 activation.
Biochem. J., 2016 Jan 15 , 473 (201-10).

11

Sexton JE et al. The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.
Neurosci. Lett., 2016 Jan 1 , 610 (36-42).

12

Urban N et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
Mol. Pharmacol., 2016 Jan , 89 (197-213).

13

Tauseef M et al. Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability.
FASEB J., 2016 Jan , 30 (102-10).

14

Riehle M et al. TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.
J. Am. Soc. Nephrol., 2016 Feb 18 , ().

15

Ohya S et al. Recent advances in therapeutic strategies that focus on the regulation of ion channel expression.
Pharmacol. Ther., 2016 Feb 16 , ().

16

Shi J et al. Store depletion induces Gαq-mediated PLCβ1 activity to stimulate TRPC1 channels in vascular smooth muscle cells.
FASEB J., 2016 Feb , 30 (702-15).

17

Guéguinou M et al. SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Oncotarget, 2016 Apr 18 , ().

18

Wu X et al. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 , 11 (e0155577).

19

Constantin B Role of Scaffolding Proteins in the Regulation of TRPC-Dependent Calcium Entry.
Adv. Exp. Med. Biol., 2016 , 898 (379-403).

20

Harper AG et al. TRP-Na(+)/Ca(2+) Exchanger Coupling.
Adv. Exp. Med. Biol., 2016 , 898 (67-85).

21

Marshall-Gradisnik S et al. Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.
Appl Clin Genet, 2016 , 9 (39-47).

22

Meijer L et al. Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.
J Innate Immun, 2016 , 8 (330-49).

23

Szteyn K et al. Divergence in endothelin-1- and bradykinin-activated store-operated calcium entry in afferent sensory neurons.
ASN Neuro, 2015 Mar-Apr , 7 ().

24

Selli C et al. Simultaneous measurement of cytosolic and mitochondrial calcium levels: observations in TRPC1-silenced hepatocellular carcinoma cells.
J Pharmacol Toxicol Methods, 2015 Mar-Apr , 72 (29-34).

25

Held K et al. TRPM3 in temperature sensing and beyond.
Temperature (Austin), 2015 Apr-Jun , 2 (201-13).

26

Liu Z et al. Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes.
Cell Calcium, 2015 Sep 3 , ().

27

Gopal S et al. Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels.
J. Cell Biol., 2015 Sep 28 , 210 (1199-211).

28

Ambrus L et al. Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes.
J. Cell. Mol. Med., 2015 Sep 25 , ().

29

Weber EW et al. TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response.
J. Exp. Med., 2015 Sep 21 , ().

30

Friedland K et al. Hyperforin: To Be or Not to Be an Activator of TRPC(6).
Rev. Physiol. Biochem. Pharmacol., 2015 Sep 19 , ().

31

Song T et al. Canonical transient receptor potential3 channels activate NF-κB to mediate allergic airway disease via PKC-α/IκB-α and calcineurin/IκB-β pathways.
FASEB J., 2015 Sep 15 , ().

32

Li S et al. Crucial role of TRPC6 in maintaining the stability of HIF-1α in glioma cells under hypoxia.
J. Cell. Sci., 2015 Sep 1 , 128 (3317-29).

33

Camacho Londoño JE et al. A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Eur. Heart J., 2015 Sep 1 , 36 (2257-66).

34

Ilatovskaya DV et al. TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases.
Am. J. Physiol. Renal Physiol., 2015 Sep 1 , 309 (F393-7).

35

Qin X et al. The possible relationship between expressions of TRPC3/5 channels and cognitive changes in rat model of chronic unpredictable stress.
Behav. Brain Res., 2015 Sep 1 , 290 (180-6).

36

Sozucan Y et al. TRP genes family expression in colorectal cancer.
Exp. Oncol., 2015 Sep , 37 (208-12).

37

Hartmann J et al. TRPC3-dependent synaptic transmission in central mammalian neurons.
J. Mol. Med., 2015 Sep , 93 (983-9).

38

Huang YW et al. Mechanosensitive store-operated calcium entry regulates the formation of cell polarity.
J. Cell. Physiol., 2015 Sep , 230 (2086-97).

39

Lindemann O et al. TRPC1 regulates fMLP-stimulated migration and chemotaxis of neutrophil granulocytes.
Biochim. Biophys. Acta, 2015 Sep , 1853 (2122-30).

40

Moccia F et al. May the remodeling of the Ca²⁺ toolkit in endothelial progenitor cells derived from cancer patients suggest alternative targets for anti-angiogenic treatment?
Biochim. Biophys. Acta, 2015 Sep , 1853 (1958-73).

41

Szabó T et al. Regulation of TRPC6 ion channels in podocytes - Implications for focal segmental glomerulosclerosis and acquired forms of proteinuric diseases.
Acta Physiol Hung, 2015 Sep , 102 (241-51).

42

Smith KA et al. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
Am. J. Respir. Cell Mol. Biol., 2015 Sep , 53 (355-67).

43

Bullich G et al. Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity.
Eur. J. Hum. Genet., 2015 Sep , 23 (1192-9).

44

Jardin I et al. STIM and calcium channel complexes in cancer.
Biochim. Biophys. Acta, 2015 Oct 9 , ().

45

Song T et al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Oct 9 , (ajplung.00148.2015).

46

Mrkonjic S et al. TRPV4 participates in the establishment of trailing adhesions and directional persistence of migrating cells.
Pflugers Arch., 2015 Oct , 467 (2107-19).

47

Li N et al. [Role of transient receptor potential canonical 1 in airway remodeling and effect of budesonide on its pulmonary expression in asthmatic guinea pigs].
Nan Fang Yi Ke Da Xue Xue Bao, 2015 Oct , 35 (1374-9).

48

Lopez E et al. FKBP25 and FKBP38 regulate non-capacitative calcium entry through TRPC6.
Biochim. Biophys. Acta, 2015 Oct , 1853 (2684-96).

49

De Souza LB et al. Fast endocytic recycling determines TRPC1-STIM1 clustering in ER-PM junctions and plasma membrane function of the channel.
Biochim. Biophys. Acta, 2015 Oct , 1853 (2709-21).

50

Kim EY et al. Syndecan-4 ectodomain evokes mobilization of podocyte TRPC6 channels and their associated pathways: An essential role for integrin signaling.
Biochim. Biophys. Acta, 2015 Oct , 1853 (2610-20).

51

Hong C et al. Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease.
Brain, 2015 Oct , 138 (3030-47).

52

Déliot N et al. Plasma membrane calcium channels in cancer: Alterations and consequences for cell proliferation and migration.
Biochim. Biophys. Acta, 2015 Oct , 1848 (2512-22).

53

Zang Z et al. Expression Patterns of TRPC1 in Cortical Lesions from Patients with Focal Cortical Dysplasia.
J. Mol. Neurosci., 2015 Oct , 57 (265-72).

54

Wei H et al. Regulation of neuropathic pain behavior by amygdaloid TRPC4/C5 channels.
Neurosci. Lett., 2015 Nov 3 , 608 (12-7).

55

Riazanski V et al. TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Proc. Natl. Acad. Sci. U.S.A., 2015 Nov 24 , 112 (E6486-95).

56

Ambudkar IS Calcium signalling in salivary gland physiology and dysfunction.
J. Physiol. (Lond.), 2015 Nov 23 , ().

57

Wu J et al. MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes.
J. Clin. Invest., 2015 Nov 2 , 125 (4091-106).

58

Ramirez GA et al. TRPC6 gene variants and neuropsychiatric lupus.
J. Neuroimmunol., 2015 Nov 15 , 288 (21-4).

59

Che H et al. Roles of store-operated Ca2+ channels in regulating cell cycling and migration of human cardiac c-kit+ progenitor cells.
Am. J. Physiol. Heart Circ. Physiol., 2015 Nov 15 , 309 (H1772-81).

60

Lopez E et al. Relationship between calcium mobilization and platelet α- and δ-granule secretion. A role for TRPC6 in thrombin-evoked δ-granule exocytosis.
Arch. Biochem. Biophys., 2015 Nov 1 , 585 (75-81).

61

Chung HK et al. RhoA enhances store-operated Ca2+ entry and intestinal epithelial restitution by interacting with TRPC1 after wounding.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Nov 1 , 309 (G759-67).

62

Bodiga VL et al. Silencing of PKC-α, TRPC1 or NF-κB expression attenuates cisplatin-induced ICAM-1 expression and endothelial dysfunction.
Biochem. Pharmacol., 2015 Nov 1 , 98 (78-91).

63

Joshi BB et al. In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome.
Gene, 2015 Nov 1 , 572 (8-16).

64

Liu Y et al. The change of spatial cognition ability in depression rat model and the possible association with down-regulated protein expression of TRPC6.
Behav. Brain Res., 2015 Nov 1 , 294 (186-93).

65

Sun Y et al. TRPC1 regulates calcium-activated chloride channels in salivary gland cells.
J. Cell. Physiol., 2015 Nov , 230 (2848-56).

66

Chauvet S et al. The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels.
Biochim. Biophys. Acta, 2015 Nov , 1853 (2957-65).

67

Kurth F et al. Transient receptor potential vanilloid 2-mediated shear-stress responses in C2C12 myoblasts are regulated by serum and extracellular matrix.
FASEB J., 2015 Nov , 29 (4726-37).

68

Zhao B et al. The role of TRPC6 in oxidative stress-induced podocyte ischemic injury.
Biochem. Biophys. Res. Commun., 2015 May 29 , 461 (413-20).

69

Lin XH et al. Upregulation of TRPC1/6 may be involved in arterial remodeling in rat.
J. Surg. Res., 2015 May 1 , 195 (334-43).

70

Wang L et al. Gq signaling causes glomerular injury by activating TRPC6.
J. Clin. Invest., 2015 May , 125 (1913-26).

71

Lu XY et al. Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.
Biochim. Biophys. Acta, 2015 May , 1853 (965-74).

72

Wong PS et al. Sex differences in the role of transient receptor potential (TRP) channels in endothelium-dependent vasorelaxation in porcine isolated coronary arteries.
Eur. J. Pharmacol., 2015 Mar 5 , 750 (108-17).

73

Tabeling C et al. CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
Proc. Natl. Acad. Sci. U.S.A., 2015 Mar 31 , 112 (E1614-23).

74

De Clercq K et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle.
Hum. Reprod., 2015 Mar 27 , ().

75

Akbulut Y et al. (-)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels.
Angew. Chem. Int. Ed. Engl., 2015 Mar 16 , 54 (3787-91).

76

Neuner SM et al. TRPC3 channels critically regulate hippocampal excitability and contextual fear memory.
Behav. Brain Res., 2015 Mar 15 , 281 (69-77).

77

Pandit MM et al. Flow regulation of endothelin-1 production in the inner medullary collecting duct.
Am. J. Physiol. Renal Physiol., 2015 Mar 15 , 308 (F541-52).

78

Louhivuori LM et al. Transient receptor potential channels and their role in modulating radial glial-neuronal interaction: a signaling pathway involving mGluR5.
Stem Cells Dev., 2015 Mar 15 , 24 (701-13).

79

Stewart TA et al. A role for calcium in the regulation of ATP-binding cassette, sub-family C, member 3 (ABCC3) gene expression in a model of epidermal growth factor-mediated breast cancer epithelial-mesenchymal transition.
Biochem. Biophys. Res. Commun., 2015 Mar 13 , 458 (509-14).

80

Rohacs T Phosphoinositide regulation of TRPV1 revisited.
Pflugers Arch., 2015 Mar 11 , ().

81

Wu QY et al. Activation of calcium-sensing receptor increases TRPC3/6 expression in T lymphocyte in sepsis.
Mol. Immunol., 2015 Mar , 64 (18-25).

82

Ma Y et al. Epoxyeicosatrienoic acids act through TRPV4-TRPC1-KCa1.1 complex to induce smooth muscle membrane hyperpolarization and relaxation in human internal mammary arteries.
Biochim. Biophys. Acta, 2015 Mar , 1852 (552-9).

83

Xu GZ et al. Increased expression of TRPC5 in cortical lesions of the focal cortical dysplasia.
J. Mol. Neurosci., 2015 Mar , 55 (561-9).

84

Peng G et al. Evolution of TRP channels inferred by their classification in diverse animal species.
Mol. Phylogenet. Evol., 2015 Mar , 84 (145-57).

85

Omura M et al. Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2.
Mol. Cell. Neurosci., 2015 Mar , 65 (114-24).

86

Kurahara LH et al. Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease.
Inflamm. Bowel Dis., 2015 Mar , 21 (496-506).

87

Zhu Y et al. Enhancement of vascular endothelial growth factor release in long-term drug-treated breast cancer via transient receptor potential channel 5-Ca(2+)-hypoxia-inducible factor 1α pathway.
Pharmacol. Res., 2015 Mar , 93 (36-42).

88

Aoki Y et al. Association between the rs1465040 single-nucleotide polymorphism close to the transient receptor potential subfamily C member 3 (TRPC3) gene and postoperative analgesic requirements.
J. Pharmacol. Sci., 2015 Mar , 127 (391-3).

89

Wang Y et al. Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry.
J. Mol. Med., 2015 Mar , 93 (327-42).

90

Asghar MY et al. Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION.
J. Biol. Chem., 2015 Jun 26 , 290 (16116-31).

91

Myeong J et al. Close spatio-association of the transient receptor potential canonical 4 (TRPC4) channel with Gαi in TRPC4 activation process.
Am. J. Physiol., Cell Physiol., 2015 Jun 1 , 308 (C879-89).

92

Yang K et al. Noggin inhibits hypoxia-induced proliferation by targeting store-operated calcium entry and transient receptor potential cation channels.
Am. J. Physiol., Cell Physiol., 2015 Jun 1 , 308 (C869-78).

93

Nakamura T et al. Prevention of PKG1α oxidation augments cardioprotection in the stressed heart.
J. Clin. Invest., 2015 Jun , 125 (2468-72).

94

Kalwa H et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes.
J. Cell. Physiol., 2015 Jun , 230 (1389-99).

95

Valero ML et al. TRPC1 and metabotropic glutamate receptor expression in rat auditory midbrain neurons.
J. Neurosci. Res., 2015 Jun , 93 (964-72).

96

Chen KH et al. SKF-96365 strongly inhibits voltage-gated sodium current in rat ventricular myocytes.
Pflugers Arch., 2015 Jun , 467 (1227-36).

97

Ru Y et al. Transient receptor potential-canonical 3 modulates sperm motility and capacitation-associated protein tyrosine phosphorylation via [Ca2+]i mobilization.
Acta Biochim. Biophys. Sin. (Shanghai), 2015 Jun , 47 (404-13).

98

Feng S et al. Ca(2+) signaling initiated by canonical transient receptor potential channels in dendritic development.
Neurosci Bull, 2015 Jun , 31 (351-6).

99

Shengyou Y et al. Influence of tacrolimus on podocyte injury inducted by angiotensin II.
J Renin Angiotensin Aldosterone Syst, 2015 Jun , 16 (260-6).

100

Forst AL et al. Podocyte Purinergic P2X4 Channels Are Mechanotransducers That Mediate Cytoskeletal Disorganization.
J. Am. Soc. Nephrol., 2015 Jul 9 , ().

101

Hanson SM et al. Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse.
Biochemistry, 2015 Jul 7 , 54 (4033-41).

102

Desai PN et al. Multiple types of calcium channels arising from alternative translation initiation of the Orai1 message.
Sci Signal, 2015 Jul 28 , 8 (ra74).

103

Abkhezr M et al. Pleiotropic signaling evoked by tumor necrosis factor in podocytes.
Am. J. Physiol. Renal Physiol., 2015 Jul 15 , 309 (F98-108).

104

Dulneva A et al. The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum.
Hum. Mol. Genet., 2015 Jul 15 , 24 (4114-25).

105

Wang J et al. Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs.
Cardiovasc. Res., 2015 Jul 1 , 107 (108-18).

106

Wang LY et al. Reduction of Store-Operated Ca(2+) Entry Correlates with Endothelial Progenitor Cell Dysfunction in Atherosclerotic Mice.
Stem Cells Dev., 2015 Jul 1 , 24 (1582-90).

107

Zhu Y et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Br. J. Pharmacol., 2015 Jul , 172 (3495-509).

108

Maier T et al. Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels.
Br. J. Pharmacol., 2015 Jul , 172 (3650-60).

109

Wang T et al. Inhibition of transient receptor potential channel 5 reverses 5-Fluorouracil resistance in human colorectal cancer cells.
J. Biol. Chem., 2015 Jan 2 , 290 (448-56).

110

Asanov A et al. Combined single channel and single molecule detection identifies subunit composition of STIM1-activated transient receptor potential canonical (TRPC) channels.
Cell Calcium, 2015 Jan , 57 (1-13).

111

Pottosin I et al. Mechanosensitive Ca²⁺-permeable channels in human leukemic cells: pharmacological and molecular evidence for TRPV2.
Biochim. Biophys. Acta, 2015 Jan , 1848 (51-9).

112

Dragoni S et al. A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.
J. Cell. Physiol., 2015 Jan , 230 (95-104).

113

Isshiki M [Bone and Calcium Research Update 2015. Intracellular Ca2+ regulation in endothelial cells].
Clin Calcium, 2015 Jan , 25 (69-78).

114

Fu J et al. Canonical transient receptor potential 4 and its small molecule modulators.
Sci China Life Sci, 2015 Jan , 58 (39-47).

115

Vachel L et al. The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity.
Cell Calcium, 2015 Jan , 57 (38-48).

116

Zhang X et al. The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats.
Mol. Cell. Biochem., 2015 Jan , 399 (155-65).

117

Veit F et al. Hypoxia-dependent reactive oxygen species signaling in the pulmonary circulation: focus on ion channels.
Antioxid. Redox Signal., 2015 Feb 20 , 22 (537-52).

118

Shalygin A et al. STIM1 and STIM2 proteins differently regulate endogenous store-operated channels in HEK293 cells.
J. Biol. Chem., 2015 Feb 20 , 290 (4717-27).

119

Xu N et al. Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1.
Am. J. Physiol., Cell Physiol., 2015 Feb 15 , 308 (C277-88).

120

Pfister S et al. Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis.
J. Comp. Neurol., 2015 Feb 15 , 523 (406-30).

121

Fogel BL et al. Do mutations in the murine ataxia gene TRPC3 cause cerebellar ataxia in humans?
Mov. Disord., 2015 Feb , 30 (284-6).

122

Fu Z et al. [Expression of transient receptor potential canonical 1 in ozone-induced inflammatory lung tissues in mice].
Nan Fang Yi Ke Da Xue Xue Bao, 2015 Feb , 35 (284-7, 291).

123

Zhang L et al. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells.
Biochim. Biophys. Acta, 2015 Feb , 1853 (377-87).

124

Song HB et al. Suppression of transient receptor potential canonical channel 4 inhibits vascular endothelial growth factor-induced retinal neovascularization.
Cell Calcium, 2015 Feb , 57 (101-8).

125

Sabourin J et al. Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.
J. Biol. Chem., 2015 Dec 18 , 290 (30530-9).

126

Sassoli C et al. Low intensity 635 nm diode laser irradiation inhibits fibroblast-myofibroblast transition reducing TRPC1 channel expression/activity: New perspectives for tissue fibrosis treatment.
Lasers Surg Med, 2015 Dec 10 , ().

127

Alptekin M et al. Gene expressions of TRP channels in glioblastoma multiforme and relation with survival.
Tumour Biol., 2015 Dec , 36 (9209-13).

128

Woo JS et al. Interaction between mitsugumin 29 and TRPC3 participates in regulating Ca(2+) transients in skeletal muscle.
Biochem. Biophys. Res. Commun., 2015 Aug 14 , 464 (133-9).

129

Iyer SC et al. Receptor channel TRPC6 orchestrate the activation of human hepatic stellate cell under hypoxia condition.
Exp. Cell Res., 2015 Aug 1 , 336 (66-75).

130

Zhou X et al. Transient Receptor Potential Channel 1 Deficiency Impairs Host Defense and Proinflammatory Responses to Bacterial Infection by Regulating Protein Kinase Cα Signaling.
Mol. Cell. Biol., 2015 Aug , 35 (2729-39).

131

Zou ZQ et al. Down-regulation of SENCR promotes smooth muscle cells proliferation and migration in db/db mice through up-regulation of FoxO1 and TRPC6.
Biomed. Pharmacother., 2015 Aug , 74 (35-41).

132

Barr JL et al. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways.
Cell Calcium, 2015 Aug , 58 (196-207).

133

Zhang E et al. Brain transient receptor potential channels and stroke.
J. Neurosci. Res., 2015 Aug , 93 (1165-83).

134

Zúñiga-García V et al. Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.
Dig. Dis. Sci., 2015 Apr 5 , ().

135

Smedlund KB et al. Increased size and cellularity of advanced atherosclerotic lesions in mice with endothelial overexpression of the human TRPC3 channel.
Proc. Natl. Acad. Sci. U.S.A., 2015 Apr 28 , 112 (E2201-6).

136

Fernandez RA et al. Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.
Am. J. Physiol., Cell Physiol., 2015 Apr 15 , 308 (C581-93).

137

Doleschal B et al. TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc. Res., 2015 Apr 1 , 106 (163-73).

138

Selli C et al. Silencing of TRPC1 regulates store-operated calcium entry and proliferation in Huh7 hepatocellular carcinoma cells.
Biomed. Pharmacother., 2015 Apr , 71 (194-200).

139

Tabur S et al. Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.
Eur Rev Med Pharmacol Sci, 2015 Apr , 19 (1388-97).

140

Hong C et al. Extracellular disulfide bridges stabilize TRPC5 dimerization, trafficking, and activity.
Pflugers Arch., 2015 Apr , 467 (703-12).

141

Sukumaran P et al. TRPC1-mediated Ca(2+) entry is essential for the regulation of hypoxia and nutrient depletion-dependent autophagy.
Cell Death Dis, 2015 , 6 (e1674).

142

Mori MX et al. Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway.
Front Pharmacol, 2015 , 6 (22).

143

Shen B et al. Plasma Membrane Mechanical Stress Activates TRPC5 Channels.
PLoS ONE, 2015 , 10 (e0122227).

144

Nazıroğlu M et al. Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs.
Curr Neuropharmacol, 2015 , 13 (248-57).

145

Carson C et al. Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
PLoS ONE, 2015 , 10 (e0127498).

146

Kim S et al. Intracellular chloride concentration of the mouse vomeronasal neuron.
BMC Neurosci, 2015 , 16 (90).

147

Vemana HP et al. A critical role for the transient receptor potential channel type 6 in human platelet activation.
PLoS ONE, 2015 , 10 (e0125764).

148

Hang P et al. Brain-derived neurotrophic factor regulates TRPC3/6 channels and protects against myocardial infarction in rodents.
Int. J. Biol. Sci., 2015 , 11 (536-45).

149

Redondo PC et al. Store-operated calcium entry: unveiling the calcium handling signalplex.
Int Rev Cell Mol Biol, 2015 , 316 (183-226).

150

Zhang Y et al. MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis.
Sci Rep, 2015 , 5 (9401).

151

Pousada G et al. Molecular and clinical analysis of TRPC6 and AGTR1 genes in patients with pulmonary arterial hypertension.
Orphanet J Rare Dis, 2015 , 10 (1).

152

Zou G et al. TRPC1, CaN and NFATC3 signaling pathway in the pathogenesis and progression of left ventricular hypertrophy in spontaneously hypertensive rats.
Clin. Exp. Hypertens., 2015 , 37 (223-34).

153

Yang LP et al. Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.
PLoS ONE, 2015 , 10 (e0136255).

154

Choi HJ et al. Astrocytes in the optic nerve head express putative mechanosensitive channels.
Mol. Vis., 2015 , 21 (749-66).

155

Kong F et al. Alpha1-Adrenergic Receptor Activation Stimulates Calcium Entry and Proliferation via TRPC6 Channels in Cultured Human Mesangial Cells.
Cell. Physiol. Biochem., 2015 , 36 (1928-38).

156

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467

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468

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470

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471

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472

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473

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474

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476

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478

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480

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481

Jiang HN et al. Involvement of TRPC channels in lung cancer cell differentiation and the correlation analysis in human non-small cell lung cancer.
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482

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484

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485

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486

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487

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488

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489

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490

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491

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492

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493

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494

Tano JY et al. Macrophage function in atherosclerosis: potential roles of TRP channels.
Channels (Austin), 2012 May-Jun , 6 (141-8).

495

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496

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497

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499

Chae HG et al. Transient receptor potential canonical channels regulate the induction of cerebellar long-term depression.
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500

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501

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502

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503

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Cardiovasc Hematol Agents Med Chem, 2012 Sep , 10 (265-74).

504

Zhang H et al. A mechanism underlying the effects of polyunsaturated fatty acids on breast cancer.
Int. J. Mol. Med., 2012 Sep , 30 (487-94).

505

Chu W et al. Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling.
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506

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507

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508

Tauseef M et al. TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation.
J. Exp. Med., 2012 Oct 22 , 209 (1953-68).

509

Ma X et al. Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells.
Proc. Natl. Acad. Sci. U.S.A., 2012 Oct 2 , 109 (16282-7).

510

Li W et al. Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice.
Proc. Natl. Acad. Sci. U.S.A., 2012 Oct 16 , 109 (17087-92).

511

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512

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513

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514

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515

Kim EY et al. Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death.
Mol. Pharmacol., 2012 Oct , 82 (728-37).

516

Jang Y et al. Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res., 2012 Oct , 35 (1823-30).

517

Nazıroğlu M et al. Role of oxidative stress and Ca²⁺ signaling on molecular pathways of neuropathic pain in diabetes: focus on TRP channels.
Neurochem. Res., 2012 Oct , 37 (2065-75).

518

McGahon MK et al. Pharmacological profiling of store-operated Ca2+ entry in retinal arteriolar smooth muscle.
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519

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520

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521

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522

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523

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524

Merriam LA et al. Pretreatment with nonselective cationic channel inhibitors blunts the PACAP-induced increase in guinea pig cardiac neuron excitability.
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525

Cioffi DL et al. Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel.
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526

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527

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528

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529

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Biochem. Biophys. Res. Commun., 2012 May 18 , 421 (750-6).

530

Kaczmarek JS et al. Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse.
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531

Tajeddine N et al. TRPC1 protein channel is major regulator of epidermal growth factor receptor signaling.
J. Biol. Chem., 2012 May 11 , 287 (16146-57).

532

Itsuki K et al. Voltage-sensing phosphatase reveals temporal regulation of TRPC3/C6/C7 channels by membrane phosphoinositides.
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533

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534

Han DH et al. Effects of Schisandra chinensis extract on the contractility of corpus cavernosal smooth muscle (CSM) and Ca2+ homeostasis in CSM cells.
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535

Kawarabayashi Y et al. Critical role of TRPC1-mediated Ca²⁺ entry in decidualization of human endometrial stromal cells.
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536

Quick K et al. TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.
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537

Zanou N et al. Trpc1 channel modulates PI3K/Akt pathway during myoblast differentiation and muscle regeneration.
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538

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540

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541

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Am. J. Physiol. Heart Circ. Physiol., 2012 Mar 15 , 302 (H1317-29).

542

Thilo F et al. Do cysteine residues regulate transient receptor potential canonical type 6 channel protein expression?
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543

Roedding AS et al. Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder.
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544

Phelan KD et al. Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Mol. Pharmacol., 2012 Mar , 81 (384-92).

545

Thilo F et al. VEGF regulates TRPC6 channels in podocytes.
Nephrol. Dial. Transplant., 2012 Mar , 27 (921-9).

546

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547

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548

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J. Neurosci., 2012 Jun 13 , 32 (8127-37).

549

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550

Thilo F et al. Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells.
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551

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552

Balbuena P et al. Malathion/oxon and lead acetate increase gene expression and protein levels of transient receptor potential canonical channel subunits TRPC1 and TRPC4 in rat endothelial cells of the blood-brain barrier.
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553

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554

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555

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J. Appl. Physiol., 2012 Jun , 112 (2077-86).

556

Ben-Mabrouk F et al. Metabotropic glutamate receptors (mGluR5) activate transient receptor potential canonical channels to improve the regularity of the respiratory rhythm generated by the pre-Bötzinger complex in mice.
Eur. J. Neurosci., 2012 Jun , 35 (1725-37).

557

Sun X et al. Effect of TRPC6 knockdown on puromycin aminonucleoside-induced podocyte injury.
J. Huazhong Univ. Sci. Technol. Med. Sci., 2012 Jun , 32 (340-5).

558

Sukumar P et al. Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin.
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559

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560

Kučka M et al. Dependence of spontaneous electrical activity and basal prolactin release on nonselective cation channels in pituitary lactotrophs.
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561

Yao H et al. Platelet-derived growth factor-BB restores human immunodeficiency virus Tat-cocaine-mediated impairment of neurogenesis: role of TRPC1 channels.
J. Neurosci., 2012 Jul 18 , 32 (9835-47).

562

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563

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564

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565

Jardin I et al. Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1.
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566

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567

Dibattista M et al. Calcium-activated chloride channels in the apical region of mouse vomeronasal sensory neurons.
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568

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569

Ilatovskaya DV et al. Regulation of TRPC6 Channels by Non-Steroidal Anti-Inflammatory Drugs.
Biochem (Mosc) Suppl Ser A Membr Cell Biol, 2012 Jul , 6 (265-272).

570

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571

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572

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Am. J. Respir. Crit. Care Med., 2012 Jan 15 , 185 (160-70).

573

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574

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575

Horinouchi T et al. Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca²⁺ entry mediated via transient receptor potential canonical 6 channels.
J. Pharmacol. Exp. Ther., 2012 Jan , 340 (143-51).

576

Liu XR et al. Enhanced store-operated Ca²+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats.
Am. J. Physiol., Cell Physiol., 2012 Jan , 302 (C77-87).

577

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578

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580

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581

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582

Matsumoto H et al. Interleukin-13 enhanced Ca2+ oscillations in airway smooth muscle cells.
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583

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584

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585

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586

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587

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588

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589

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590

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591

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592

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593

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Arterioscler. Thromb. Vasc. Biol., 2012 Feb , 32 (378-85).

594

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Am. J. Physiol. Renal Physiol., 2012 Feb , 302 (F298-307).

595

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Acta Physiol (Oxf), 2012 Feb , 204 (227-37).

596

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597

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598

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599

Sukumaran P et al. Canonical transient receptor potential channel 2 (TRPC2) as a major regulator of calcium homeostasis in rat thyroid FRTL-5 cells: importance of protein kinase C δ (PKCδ) and stromal interaction molecule 2 (STIM2).
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600

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601

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602

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603

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605

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608

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613

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614

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