ClIC1

1

Hare JE et al. The interaction of human chloride intracellular channel protein 1 (CLIC1) with lipid bilayers: a fluorescence study.
Biochemistry, 2016 Jun 14 , ().

2

Ponnalagu D et al. Molecular identity of cardiac mitochondrial chloride intracellular channel proteins.
Mitochondrion, 2016 Jan 9 , 27 (6-14).

3

Fang C et al. Identification of Palmitoylated Transitional Endoplasmic Reticulum ATPase by Proteomic Technique and Pan Antipalmitoylation Antibody.
J. Proteome Res., 2016 Feb 17 , ().

4

Hossain KR et al. Cholesterol Promotes Interaction of the Protein CLIC1 with Phospholipid Monolayers at the Air-Water Interface.
Membranes (Basel), 2016 , 6 ().

5

Salao K et al. CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis.
Biol Open, 2016 , 5 (620-30).

6

Lu J et al. Chloride intracellular channel 1 (CLIC1) is activated and functions as an oncogene in pancreatic cancer.
Med. Oncol., 2015 Jun , 32 (616).

7

Ye Y et al. CLIC1 a novel biomarker of intraperitoneal metastasis in serous epithelial ovarian cancer.
Tumour Biol., 2015 Jun , 36 (4175-9).

8

Ding Q et al. CLIC1 overexpression is associated with poor prognosis in gallbladder cancer.
Tumour Biol., 2015 Jan , 36 (193-8).

9

Wei X et al. Chloride intracellular channel 1 participates in migration and invasion of hepatocellular carcinoma by targeting maspin.
J. Gastroenterol. Hepatol., 2015 Jan , 30 (208-16).

10

Cross M et al. Glutamate 85 and glutamate 228 contribute to the pH-response of the soluble form of chloride intracellular channel 1.
Mol. Cell. Biochem., 2015 Jan , 398 (83-93).

11

Zhang J et al. Clic1 plays a role in mouse hepatocarcinoma via modulating Annexin A7 and Gelsolin in vitro and in vivo.
Biomed. Pharmacother., 2015 Feb , 69 (416-9).

12

Gurski LA et al. Relocation of CLIC1 promotes tumor cell invasion and colonization of fibrin.
Mol. Cancer Res., 2015 Feb , 13 (273-80).

13

Al Khamici H et al. Members of the chloride intracellular ion channel protein family demonstrate glutaredoxin-like enzymatic activity.
PLoS ONE, 2015 , 10 (e115699).

14

Tian Y et al. Chloride intracellular channel 1 regulates prostate cancer cell proliferation and migration through the MAPK/ERK pathway.
Cancer Biother. Radiopharm., 2014 Oct , 29 (339-44).

15

Gritti M et al. Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current.
Oncotarget, 2014 Nov 30 , 5 (11252-68).

16

Averaimo S et al. CLIC1 functional expression is required for cAMP-induced neurite elongation in post-natal mouse retinal ganglion cells.
J. Neurochem., 2014 Nov , 131 (444-56).

17

Chernet BT et al. Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range.
Oncotarget, 2014 May 30 , 5 (3287-306).

18

Murray E et al. Quantitative proteomic profiling of pleomorphic human sarcoma identifies CLIC1 as a dominant pro-oncogenic receptor expressed in diverse sarcoma types.
J. Proteome Res., 2014 May 2 , 13 (2543-59).

19

Peter B et al. A conserved cationic motif enhances membrane binding and insertion of the chloride intracellular channel protein 1 transmembrane domain.
Eur. Biophys. J., 2014 Jun 13 , ().

20

Xiao P et al. [Expression of CLIC1 and IGFBP7 in complete hydatidiform mole].
Sichuan Da Xue Xue Bao Yi Xue Ban, 2014 Jul , 45 (612-7).

21

Nanaware PP et al. Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein--evidence for a common hot spot site at the interface and its functional relevance.
Proteins, 2014 Jul , 82 (1283-300).

22

Peter B et al. A Lys-Trp Cation-π Interaction Mediates the Dimerization and Function of the Chloride Intracellular Channel Protein 1 Transmembrane Domain.
Biochemistry, 2014 Jan 14 , 53 (57-67).

23

Wang P et al. Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathway.
World J. Gastroenterol., 2014 Feb 28 , 20 (2071-8).

24

Sasaki S et al. Actin directly interacts with different membrane channel proteins and influences channel activities: AQP2 as a model.
Biochim. Biophys. Acta, 2014 Feb , 1838 (514-20).

25

Peretti M et al. Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets.
Biochim. Biophys. Acta, 2014 Dec 26 , ().

26

Zhang J et al. Ech1 is a potent suppressor of lymphatic metastasis in hepatocarcinoma.
Biomed. Pharmacother., 2013 Sep , 67 (557-60).

27

Setti M et al. Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells.
J. Natl. Cancer Inst., 2013 Oct 10 , ().

28

Zhang S et al. Chloride intracellular channel 1 is overexpression in hepatic tumor and correlates with a poor prognosis.
APMIS, 2013 Nov , 121 (1047-53).

29

Skaper SD et al. Intracellular Ion Channel CLIC1: Involvement in Microglia-Mediated β-Amyloid Peptide(1-42) Neurotoxicity.
Neurochem. Res., 2013 Jun 7 , ().

30

Tang HY et al. Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.
J Proteomics, 2013 Aug 26 , 89 (165-78).

31

Peter B et al. Membrane mimetics induce helix formation and oligomerization of the chloride intracellular channel protein 1 transmembrane domain.
Biochemistry, 2013 Apr 23 , 52 (2739-49).

32

Costa JA et al. Wicking: a rapid method for manually inserting ion channels into planar lipid bilayers.
PLoS ONE, 2013 , 8 (e60836).

33

Valenzuela SM et al. Regulation of the membrane insertion and conductance activity of the metamorphic chloride intracellular channel protein CLIC1 by cholesterol.
PLoS ONE, 2013 , 8 (e56948).

34

Jones PM et al. Computational Analysis of the Soluble Form of the Intracellular Chloride Ion Channel Protein CLIC1.
Biomed Res Int, 2013 , 2013 (170586).

35

Averaimo S et al. Point mutations in the transmembrane region of the clic1 ion channel selectively modify its biophysical properties.
PLoS ONE, 2013 , 8 (e74523).

36

Jiang L et al. Intracellular chloride channel protein CLIC1 regulates macrophage functions via modulation of phagosomal acidification.
J. Cell. Sci., 2012 Sep 6 , ().

37

Legg-E'silva D et al. Role of arginine 29 and glutamic acid 81 interactions in the conformational stability of human chloride intracellular channel 1.
Biochemistry, 2012 Oct 9 , 51 (7854-62).

38

Zheng DL et al. PA28β regulates cell invasion of gastric cancer via modulating the expression of chloride intracellular channel 1.
J. Cell. Biochem., 2012 May , 113 (1537-46).

39

Knowles LM et al. CLT1 targets angiogenic endothelium through CLIC1 and fibronectin.
Angiogenesis, 2012 Mar , 15 (115-29).

40

Ma PF et al. Function of chloride intracellular channel 1 in gastric cancer cells.
World J. Gastroenterol., 2012 Jun 28 , 18 (3070-80).

41

Wang P et al. Regulation of colon cancer cell migration and invasion by CLIC1-mediated RVD.
Mol. Cell. Biochem., 2012 Jun , 365 (313-21).

42

Achilonu I et al. Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1.
Biochemistry, 2012 Feb 7 , 51 (995-1004).

43

Li RK et al. Chloride intracellular channel 1 is an important factor in the lymphatic metastasis of hepatocarcinoma.
Biomed. Pharmacother., 2012 Apr , 66 (167-72).

44

Wang L et al. Elevated expression of chloride intracellular channel 1 is correlated with poor prognosis in human gliomas.
J. Exp. Clin. Cancer Res., 2012 , 31 (44).

45

Goodchild SC et al. Transmembrane extension and oligomerisation of the CLIC1 chloride intracellular channel protein upon membrane interaction.
, 2011 Nov 14 , ().

46

Shi ZH et al. CLIC1 protein: a candidate prognostic biomarker for malignant-transformed hydatidiform moles.
Int. J. Gynecol. Cancer, 2011 Jan , 21 (153-60).

47

Wang W et al. The expression and clinical significance of CLIC1 and HSP27 in lung adenocarcinoma.
Tumour Biol., 2011 Dec , 32 (1199-208).

48

Averaimo S et al. Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress.
FEBS Lett., 2010 May 17 , 584 (2076-84).

49

Goodchild SC et al. Metamorphic Response of the CLIC1 Chloride Intracellular Ion Channel Protein upon Membrane Interaction.
, 2010 Jun 8 , ().

50

Klausen TK et al. Monovalent Ions Control Proliferation of Ehrlich Lettre Ascites cells.
, 2010 Jun 30 , ().

51

Kim JS et al. Chloride intracellular channel 1 identified using proteomic analysis plays an important role in the radiosensitivity of HEp-2 cells via reactive oxygen species production.
Proteomics, 2010 Jul , 10 (2589-604).

52

Song MY et al. [Localization and expression of CLIC1 in hepatocarcinoma ascites cell lines with high or low potentials of lymphatic spread].
Zhonghua Bing Li Xue Za Zhi, 2010 Jul , 39 (463-6).

53

Qiu MR et al. Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene.
, 2010 Jan 4 , 48 (127-136).

54

Littler DR et al. The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?
, 2010 Jan 19 , ().

55

Li RK et al. [Effects of silencing chloride intracellular channel 1 gene expression on the proliferation and invasion of mouse hepatocellular carcinoma cell lines].
Zhonghua Gan Zang Bing Za Zhi, 2010 Feb , 18 (131-5).

56

Skaper SD Ion Channels on Microglia: Therapeutic Targets for Neuroprotection.
, 2010 Dec 14 , ().

57

Stoychev SH et al. Structural dynamics of soluble chloride intracellular channel protein CLIC1 examined by amide hydrogen-deuterium exchange mass spectrometry.
Biochemistry, 2009 Sep 8 , 48 (8413-21).

58

Chalothorn D et al. Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain.
Circ. Res., 2009 Jul 2 , 105 (89-98).

59

Yang JY et al. Chloride intracellular channel 1 regulates osteoblast differentiation.
Bone, 2009 Dec , 45 (1175-85).

60

Chang YH et al. Cell secretome analysis using hollow fiber culture system leads to the discovery of CLIC1 protein as a novel plasma marker for nasopharyngeal carcinoma.
J. Proteome Res., 2009 Dec , 8 (5465-74).

61

Wang JW et al. Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1.
Cancer Lett., 2009 Aug 18 , 281 (71-81).

62

Goodchild SC et al. Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane.
Eur. Biophys. J., 2009 Apr 23 , ().

63

Kang MK et al. Pharmacologic blockade of chloride channel synergistically enhances apoptosis of chemotherapeutic drug-resistant cancer stem cells.
Biochem. Biophys. Res. Commun., 2008 Sep 5 , 373 (539-44).

64

Petrova DT et al. Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.
Clin. Biochem., 2008 Oct , 41 (1224-36).

65

Milton RH et al. CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.
J. Neurosci., 2008 Nov 5 , 28 (11488-99).

66

Fanucchi S et al. Formation of an unfolding intermediate state of soluble chloride intracellular channel protein CLIC1 at acidic pH.
Biochemistry, 2008 Nov 4 , 47 (11674-81).

67

Paradisi S et al. Blockade of chloride intracellular ion channel 1 stimulates Abeta phagocytosis.
J. Neurosci. Res., 2008 Aug 15 , 86 (2488-98).

68

Littler DR et al. Comparison of vertebrate and invertebrate CLIC proteins: the crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC.
Proteins, 2008 Apr , 71 (364-78).

69

Singh H et al. CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels.
Mol. Membr. Biol., 2007 Jan-Feb , 24 (41-52).

70

Ducharme G et al. Small-conductance Cl- channels contribute to volume regulation and phagocytosis in microglia.
Eur. J. Neurosci., 2007 Oct , 26 (2119-30).

71

Cromer BA et al. Structure of the Janus protein human CLIC2.
J. Mol. Biol., 2007 Nov 30 , 374 (719-31).

72

Chen CD et al. Overexpression of CLIC1 in human gastric carcinoma and its clinicopathological significance.
Proteomics, 2007 Jan , 7 (155-67).

73

Singh H et al. Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin.
FEBS J., 2007 Dec , 274 (6306-16).

74

Ulmasov B et al. Tissue and subcellular distribution of CLIC1.
BMC Cell Biol., 2007 , 8 (8).

75

Sun HJ et al. A proteomic analysis during serial subculture and osteogenic differentiation of human mesenchymal stem cell.
J. Orthop. Res., 2006 Nov , 24 (2059-71).

76

Li Y et al. Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals.
Biochem. Biophys. Res. Commun., 2006 May 19 , 343 (1272-8).

77

Singh H et al. Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore.
Biophys. J., 2006 Mar 1 , 90 (1628-38).

78

Edwards JC The CLIC1 chloride channel is regulated by the cystic fibrosis transmembrane conductance regulator when expressed in Xenopus oocytes.
J. Membr. Biol., 2006 , 213 (39-46).

79

Saeki K et al. Proteomic analysis on insulin signaling in human hematopoietic cells: identification of CLIC1 and SRp20 as novel downstream effectors of insulin.
Am. J. Physiol. Endocrinol. Metab., 2005 Sep , 289 (E419-28).

80

Littler DR et al. Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.
FEBS J., 2005 Oct , 272 (4996-5007).

81

Schaller S et al. The role of chloride channels in osteoclasts: ClC-7 as a target for osteoporosis treatment.
Drug News Perspect., 2005 Oct , 18 (489-95).

82

Oakley AJ Glutathione transferases: new functions.
Curr. Opin. Struct. Biol., 2005 Dec , 15 (716-23).

83

Myers K et al. Identification of chloride intracellular channel proteins in spermatozoa.
FEBS Lett., 2004 May 21 , 566 (136-40).

84

Littler DR et al. The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition.
J. Biol. Chem., 2004 Mar 5 , 279 (9298-305).

85

Novarino G et al. Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity.
J. Neurosci., 2004 Jun 9 , 24 (5322-30).

86

Schaller S et al. The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation.
J. Bone Miner. Res., 2004 Jul , 19 (1144-53).

87

Ashley RH Challenging accepted ion channel biology: p64 and the CLIC family of putative intracellular anion channel proteins (Review).
Mol. Membr. Biol., 2003 Jan-Mar , 20 (1-11).

88

Shorning BY et al. Molecular cloning and developmental expression of two Chloride Intracellular Channel (CLIC) genes in Xenopus laevis.
Dev. Genes Evol., 2003 Oct , 213 (514-8).

89

Friedli M et al. Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12.
Gene, 2003 Nov 27 , 320 (31-40).

90

Fan L et al. Interaction of Sedlin with chloride intracellular channel proteins.
FEBS Lett., 2003 Apr 10 , 540 (77-80).

91

Cromer BA et al. From glutathione transferase to pore in a CLIC.
Eur. Biophys. J., 2002 Sep , 31 (356-64).

92

Shanks RA et al. AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member.
J. Biol. Chem., 2002 Oct 25 , 277 (40973-80).

93

Tulk BM et al. CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel.
Am. J. Physiol., Cell Physiol., 2002 May , 282 (C1103-12).

94

Warton K et al. Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1.
J. Biol. Chem., 2002 Jul 19 , 277 (26003-11).

95

Rønnov-Jessen L et al. Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts.
Am. J. Pathol., 2002 Aug , 161 (471-80).

96

Harrop SJ et al. Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J. Biol. Chem., 2001 Nov 30 , 276 (44993-5000).

97

Dulhunty A et al. The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator.
J. Biol. Chem., 2001 Feb 2 , 276 (3319-23).

98

Berryman M et al. Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.
Mol. Biol. Cell, 2000 May , 11 (1509-21).

99

Qian Z et al. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel.
J. Biol. Chem., 1999 Jan 15 , 274 (1621-7).

100

Heiss NS et al. Genomic structure of a novel chloride channel gene, CLIC2, in Xq28.
Genomics, 1997 Oct 1 , 45 (224-8).