ClIC4

1

Ponnalagu D et al. Molecular identity of cardiac mitochondrial chloride intracellular channel proteins.
Mitochondrion, 2016 Jan 9 , 27 (6-14).

2

Chou SY et al. CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking.
Nat Commun, 2016 , 7 (10412).

3

Tasiopoulou V et al. Transcriptional over-expression of chloride intracellular channels 3 and 4 in malignant pleural mesothelioma.
Comput Biol Chem, 2015 Sep 28 , 59 (111-116).

4

Lucitti JL et al. Chloride intracellular channel 4 is required for maturation of the cerebral collateral circulation.
Am. J. Physiol. Heart Circ. Physiol., 2015 Oct , 309 (H1141-50).

5

Lecat S et al. A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways.
Mol. Cell Proteomics, 2015 May , 14 (1385-99).

6

Raedler D et al. Identification of novel immune phenotypes for allergic and nonallergic childhood asthma.
J. Allergy Clin. Immunol., 2015 Jan , 135 (81-91).

7

Deng YJ et al. CLIC4, ERp29, and Smac/DIABLO derived from metastatic cancer stem-like cells stratify prognostic risks of colorectal cancer.
Clin. Cancer Res., 2014 Jul 15 , 20 (3809-17).

8

Shukla A et al. CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma.
Oncogene, 2014 Feb 13 , 33 (842-50).

9

Peretti M et al. Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets.
Biochim. Biophys. Acta, 2014 Dec 26 , ().

10

Argenzio E et al. CLIC4 regulates cell adhesion and β1 integrin trafficking.
J. Cell. Sci., 2014 Dec 15 , 127 (5189-203).

11

Wojciak-Stothard B et al. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
Circulation, 2014 Apr 29 , 129 (1770-80).

12

Padmakumar V et al. Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line.
BMC Dev. Biol., 2014 , 14 (24).

13

Edwards JC et al. Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery.
BMC Nephrol, 2014 , 15 (54).

14

Okudela K et al. Proteome analysis for downstream targets of oncogenic KRAS--the potential participation of CLIC4 in carcinogenesis in the lung.
PLoS ONE, 2014 , 9 (e87193).

15

Yan H et al. Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms.
Nat Commun, 2014 , 5 (3334).

16

Chiang PC et al. Chloride intracellular channel 4 involves in the reduced invasiveness of cancer cells treated by photodynamic therapy.
Lasers Surg Med, 2013 Jan , 45 (38-47).

17

Tang HY et al. Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.
J Proteomics, 2013 Aug 26 , 89 (165-78).

18

Xu Y et al. Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells.
Oncol. Rep., 2013 Apr , 29 (1483-91).

19

Leanza L et al. Intracellular ion channels and cancer.
Front Physiol, 2013 , 4 (227).

20

Suh KS et al. CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.
Carcinogenesis, 2012 May , 33 (986-95).

21

Bhandari P et al. Chloride intracellular channels modulate acute ethanol behaviors in Drosophila, Caenorhabditis elegans and mice.
Genes Brain Behav., 2012 Jun , 11 (387-97).

22

Padmakumar VC et al. Spontaneous skin erosions and reduced skin and corneal wound healing characterize CLIC4(NULL) mice.
Am. J. Pathol., 2012 Jul , 181 (74-84).

23

Malik M et al. Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation.
Proc. Natl. Acad. Sci. U.S.A., 2012 Apr 17 , 109 (6130-5).

24

Zhong J et al. Inhibition of CLIC4 enhances autophagy and triggers mitochondrial and ER stress-induced apoptosis in human glioma U251 cells under starvation.
PLoS ONE, 2012 , 7 (e39378).

25

He G et al. Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide.
Eur. J. Immunol., 2011 May , 41 (1221-30).

26

Mynott AV et al. Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4.
FEBS J., 2011 May , 278 (1662-75).

27

Palmfeldt J et al. Proteomics reveals redox regulation is disrupted in patients with ethylmalonic encephalopathy.
, 2011 Mar 16 , ().

28

Shukla A et al. CLIC4 and Schnurri-2: a dynamic duo in TGF-beta signaling with broader implications in cellular homeostasis and disease.
Nucleus, 2010 Mar-Apr , 1 (144-9).

29

Chuang JZ et al. Chloride intracellular channel 4 is critical for the epithelial morphogenesis of RPE cells and retinal attachment.
Mol. Biol. Cell, 2010 Sep , 21 (3017-28).

30

Malik M et al. S-nitrosylation regulates nuclear translocation of chloride intracellular channel protein CLIC4.
J. Biol. Chem., 2010 Jul 30 , 285 (23818-28).

31

Spiekerkoetter E et al. S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4.
Circ. Res., 2009 Sep 25 , 105 (639-47, 13 p following 647).

32

Yao Q et al. CLIC4 mediates TGF-beta1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer.
Oncol. Rep., 2009 Sep , 22 (541-8).

33

Ponsioen B et al. Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.
Mol. Biol. Cell, 2009 Nov , 20 (4664-72).

34

Ulmasov B et al. Chloride intracellular channel protein-4 functions in angiogenesis by supporting acidification of vacuoles along the intracellular tubulogenic pathway.
Am. J. Pathol., 2009 Mar , 174 (1084-96).

35

Shukla A et al. TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3.
Nat. Cell Biol., 2009 Jun , 11 (777-84).

36

Chalothorn D et al. Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain.
Circ. Res., 2009 Jul 2 , 105 (89-98).

37

Tung JJ et al. Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro.
Angiogenesis, 2009 , 12 (209-20).

38

Yao Q et al. Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models.
Mol. Cancer, 2009 , 8 (78).

39

Maeda K et al. CLIC4 interacts with histamine H3 receptor and enhances the receptor cell surface expression.
Biochem. Biophys. Res. Commun., 2008 May 2 , 369 (603-8).

40

Littler DR et al. Comparison of vertebrate and invertebrate CLIC proteins: the crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC.
Proteins, 2008 Apr , 71 (364-78).

41

Singh H et al. CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels.
Mol. Membr. Biol., 2007 Jan-Feb , 24 (41-52).

42

Suh KS et al. Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers.
Clin. Cancer Res., 2007 Jan 1 , 13 (121-31).

43

Singh H et al. Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin.
FEBS J., 2007 Dec , 274 (6306-16).

44

Suh KS et al. CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation.
J. Cell. Sci., 2007 Aug 1 , 120 (2631-40).

45

Suh KS et al. CLIC4, skin homeostasis and cutaneous cancer: surprising connections.
Mol. Carcinog., 2007 Aug , 46 (599-604).

46

Adamkiewicz J et al. Proteomic profile of mouse fibroblasts with a targeted disruption of the peroxisome proliferator activated receptor-beta/delta gene.
Proteomics, 2007 Apr , 7 (1208-16).

47

Li Y et al. Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals.
Biochem. Biophys. Res. Commun., 2006 May 19 , 343 (1272-8).

48

Shiio Y et al. Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4.
J. Biol. Chem., 2006 Feb 3 , 281 (2750-6).

49

Li DF et al. Expression, purification, crystallization and preliminary crystallographic analysis of the human intracellular chloride channel protein CLIC4.
Protein Pept. Lett., 2006 , 13 (641-3).

50

Littler DR et al. Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.
FEBS J., 2005 Oct , 272 (4996-5007).

51

Suh KS et al. CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapy.
J. Investig. Dermatol. Symp. Proc., 2005 Nov , 10 (105-9).

52

Suh KS et al. Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth.
Cancer Res., 2005 Jan 15 , 65 (562-71).

53

Bohman S et al. Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.
J. Biol. Chem., 2005 Dec 23 , 280 (42397-404).

54

Myers K et al. Identification of chloride intracellular channel proteins in spermatozoa.
FEBS Lett., 2004 May 21 , 566 (136-40).

55

Suh KS et al. The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis.
J. Biol. Chem., 2004 Feb 6 , 279 (4632-41).

56

Ashley RH Challenging accepted ion channel biology: p64 and the CLIC family of putative intracellular anion channel proteins (Review).
Mol. Membr. Biol., 2003 Jan-Mar , 20 (1-11).

57

Shorning BY et al. Molecular cloning and developmental expression of two Chloride Intracellular Channel (CLIC) genes in Xenopus laevis.
Dev. Genes Evol., 2003 Oct , 213 (514-8).

58

Berryman MA et al. CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells.
Cell Motil. Cytoskeleton, 2003 Nov , 56 (159-72).

59

Proutski I et al. Overexpressed chloride intracellular channel protein CLIC4 (p64H1) is an essential component of novel plasma membrane anion channels.
Biochem. Biophys. Res. Commun., 2002 Sep 20 , 297 (317-22).

60

Fernandez-Salas E et al. mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53.
Mol. Cell. Biol., 2002 Jun , 22 (3610-20).

61

Rønnov-Jessen L et al. Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-beta1-mediated conversion of fibroblasts to myofibroblasts.
Am. J. Pathol., 2002 Aug , 161 (471-80).

62

Suginta W et al. Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms.
Biochem. J., 2001 Oct 1 , 359 (55-64).

63

Berryman M et al. Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.
Mol. Biol. Cell, 2000 May , 11 (1509-21).