Kv1.5
769 literature references associated to Kv1.5
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Wu W
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Molecular Basis of Cardiac Delayed Rectifier Potassium Channel Function and Pharmacology.
Card Electrophysiol Clin,
2016
Jun
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Kojima A
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Serum albumin attenuates the open-channel blocking effects of propofol on the human Kv1.5 channel.
Eur. J. Pharmacol.,
2016
Jul
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3
Subramani B
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Generation and characterization of human cardiac resident and non-resident mesenchymal stem cell.
Cytotechnology,
2016
Jan
28
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4
Lee HM
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Blockade of Kv1.5 by paroxetine, an antidepressant drug.
Korean J. Physiol. Pharmacol.,
2016
Jan
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5
Ryland KE
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Promoter Methylation Analysis Reveals That KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation.
Mol. Cancer Res.,
2016
Jan
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6
Crump SM
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Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice.
FASEB J.,
2016
Jan
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7
Doczi MA
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Developmental expression of Kv1 voltage-gated potassium channels in the avian hypothalamus.
Neurosci. Lett.,
2016
Feb
1
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8
Ou X
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Myricetin inhibits Kv1.5 channels in HEK293 cells.
Mol Med Rep,
2016
Feb
, 13 (1725-31).
9
Kajanus J
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Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach.
Bioorg. Med. Chem. Lett.,
2016
Apr
15
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10
Ahmed M
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SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5).
Cell. Physiol. Biochem.,
2016
, 38 (359-67).
11
Zhao Y
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Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord,
2016
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12
Ohanyan V
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Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation.
Circ. Res.,
2015
Sep
11
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13
Wang YY
et al.
[Effect of ERK1/2 on rat pulmonary artery smooth muscle cells Kv1.5 channel in the process of hypoxia].
Zhongguo Ying Yong Sheng Li Xue Za Zhi,
2015
Sep
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14
Li P
et al.
E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells.
J. Mol. Cell. Cardiol.,
2015
Sep
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15
Kojima A
et al.
Interaction of propofol with voltage-gated human Kv1.5 channel through specific amino acids within the pore region.
Eur. J. Pharmacol.,
2015
Oct
5
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16
Asano S
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Cecal inoculum peritonitis: An alternative model for sepsis vascular dysfunction study.
Life Sci.,
2015
Nov
15
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17
Jin SS
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Antiarrhythmic ionic mechanism of Guanfu base A--Selective inhibition of late sodium current in isolated ventricular myocytes from guinea pigs.
Chin J Nat Med,
2015
May
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18
Fancher IS
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Diphenyl phosphine oxide-1-sensitive K(+) channels contribute to the vascular tone and reactivity of resistance arteries from brain and skeletal muscle.
Microcirculation,
2015
May
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19
Kiper AK
et al.
Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
Pflugers Arch.,
2015
May
, 467 (1081-90).
20
Lloyd J
et al.
Pseudosaccharin amines as potent and selective KV1.5 blockers.
Bioorg. Med. Chem. Lett.,
2015
Mar
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21
Turnow K
et al.
Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito.
Basic Res. Cardiol.,
2015
Mar
, 110 (5).
22
Yang L
et al.
Intravenous anesthetic propofol inhibits multiple human cardiac potassium channels.
Anesthesiology,
2015
Mar
, 122 (571-84).
23
Hayashi K
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Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.
Circ Arrhythm Electrophysiol,
2015
Jun
30
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24
Warsi J
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Regulation of Voltage-Gated K(+) Channel Kv1.5 by the Janus Kinase JAK3.
J. Membr. Biol.,
2015
Jun
23
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25
Pippucci T
et al.
Homozygous NOTCH3 null mutation and impaired NOTCH3 signaling in recessive early-onset arteriopathy and cavitating leukoencephalopathy.
EMBO Mol Med,
2015
Jun
, 7 (848-58).
26
Yu J
et al.
Inhibitory effects of cortisone and hydrocortisone on human Kv1.5 channel currents.
Eur. J. Pharmacol.,
2015
Jan
5
, 746 (158-66).
27
Ednie AR
et al.
Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly.
J. Biol. Chem.,
2015
Jan
30
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28
Chong E
et al.
Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Heart Rhythm,
2015
Jan
30
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29
Chapalamadugu KC
et al.
High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulation.
Toxicol. Appl. Pharmacol.,
2015
Jan
1
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30
Zheng L
et al.
Tanshinone IIA attenuates hypoxic pulmonary hypertension via modulating KV currents.
Respir Physiol Neurobiol,
2015
Jan
1
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31
Devalla HD
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Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
EMBO Mol Med,
2015
Feb
19
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32
Männikkö R
et al.
Pharmacological and electrophysiological characterisation of hERG activator AZSMO-23.
Br. J. Pharmacol.,
2015
Feb
12
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33
Elvira B
et al.
SPAK and OSR1 sensitivity of voltage-gated K+ channel Kv1.5.
J. Membr. Biol.,
2015
Feb
, 248 (59-66).
34
Gasparoli L
et al.
New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Mol. Pharmacol.,
2015
Feb
, 87 (183-96).
35
Rudakova E
et al.
Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes.
Pflugers Arch.,
2015
Feb
, 467 (299-309).
36
Ryland KE
et al.
Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stress.
Oncogene,
2015
Aug
27
, 34 (4591-600).
37
Kidd MW
et al.
Intravascular pressure enhances the abundance of functional Kv1.5 channels at the surface of arterial smooth muscle cells.
Sci Signal,
2015
Aug
18
, 8 (ra83).
38
Lee JY
et al.
The role of K⁺ conductances in regulating membrane excitability in human gastric corpus smooth muscle.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2015
Apr
1
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39
Wang J
et al.
Oral administration of putrescine and proline during the suckling period improves epithelial restitution after early weaning in piglets.
J. Anim. Sci.,
2015
Apr
, 93 (1679-88).
40
Lang F
On the putative purpose of AMPK sensitive Kv1.5 K(+) channel regulation.
Channels (Austin),
2015
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41
Yamanushi TT
et al.
Comparison of formaldehyde and methanol fixatives used in the detection of ion channel proteins in isolated rat ventricular myocytes by immunofluorescence labelling and confocal microscopy.
Folia Morphol. (Warsz),
2015
, 74 (258-61).
42
Ou XH
et al.
Remodeling of Kv1.5 channel in right atria from Han Chinese patients with atrial fibrillation.
Med. Sci. Monit.,
2015
, 21 (1207-13).
43
Dai ZK
et al.
The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K⁺-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries.
Int. J. Biol. Sci.,
2015
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44
Bartok A
et al.
Margatoxin is a non-selective inhibitor of human Kv1.3 K(+) channels.
Toxicon,
2014
Sep
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45
Singhal R
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Colchicine suppresses atrial fibrillation in failing heart.
Int. J. Cardiol.,
2014
Oct
20
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46
Li B
et al.
Dichloroacetate prevents but not reverses the formation of neointimal lesions in a rat model of severe pulmonary arterial hypertension.
Mol Med Rep,
2014
Oct
, 10 (2144-52).
47
Carrisoza-Gaytán R
et al.
Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephron.
J. Mol. Histol.,
2014
Oct
, 45 (583-97).
48
Frolov RV
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Celecoxib and ion channels: a story of unexpected discoveries.
Eur. J. Pharmacol.,
2014
May
5
, 730 (61-71).
49
Fischer F
et al.
Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII.
Naunyn Schmiedebergs Arch. Pharmacol.,
2014
May
, 387 (469-76).
50
Schumacher-Bass SM
et al.
Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.
Circ. Res.,
2014
Mar
14
, 114 (982-92).
51
Olsson RI
et al.
Lactam sulfonamides as potent inhibitors of the Kv1.5 potassium ion channel.
Bioorg. Med. Chem. Lett.,
2014
Mar
1
, 24 (1269-73).
52
Guo X
et al.
Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).
Eur J Med Chem,
2014
Jun
23
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53
Wu CT
et al.
Disease and region-related cardiac fibroblast potassium current variations and potential functional significance.
Cardiovasc. Res.,
2014
Jun
1
, 102 (487-96).
54
Wang T
et al.
Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2.
Mol. Pharmacol.,
2014
Jun
, 85 (877-86).
55
Johnson JA
et al.
Design, synthesis and evaluation of phenethylaminoheterocycles as Kv1.5 inhibitors.
Bioorg. Med. Chem. Lett.,
2014
Jul
15
, 24 (3018-22).
56
Luna-Ramírez K
et al.
Structure, molecular modeling, and function of the novel potassium channel blocker urotoxin isolated from the venom of the Australian scorpion Urodacus yaschenkoi.
Mol. Pharmacol.,
2014
Jul
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57
Iwata K
et al.
Deficiency of NOX1/nicotinamide adenine dinucleotide phosphate, reduced form oxidase leads to pulmonary vascular remodeling.
Arterioscler. Thromb. Vasc. Biol.,
2014
Jan
, 34 (110-9).
58
Wang G
et al.
Early onset severe pulmonary arterial hypertension with 'two-hit' digenic mutations in both BMPR2 and KCNA5 genes.
Int. J. Cardiol.,
2014
Dec
20
, 177 (e167-9).
59
Vu TT
et al.
Soluble prokaryotic expression and purification of crotamine using an N-terminal maltose-binding protein tag.
Toxicon,
2014
Dec
15
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60
Cidad P
et al.
K+ channels expression in hypertension after arterial injury, and effect of selective Kv1.3 blockade with PAP-1 on intimal hyperplasia formation.
Cardiovasc Drugs Ther,
2014
Dec
, 28 (501-11).
61
Ahmed M
et al.
Down-regulation of K⁺ channels by human parvovirus B19 capsid protein VP1.
Biochem. Biophys. Res. Commun.,
2014
Aug
8
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62
Schmitt N
et al.
Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia.
Physiol. Rev.,
2014
Apr
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63
Li Z
et al.
Exercise training reverses alterations in Kv and BKCa channel molecular expression in thoracic aorta smooth muscle cells from spontaneously hypertensive rats.
J. Vasc. Res.,
2014
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64
Dun W
et al.
SAP97 and cortactin remodeling in arrhythmogenic Purkinje cells.
PLoS ONE,
2014
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65
Odagiri F
et al.
Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.
PLoS ONE,
2014
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66
Tabarean IV
Electrical remodeling of preoptic GABAergic neurons involves the Kv1.5 subunit.
PLoS ONE,
2014
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67
Nielsen JB
et al.
Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation.
Biomark Med,
2014
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68
Wang J
et al.
Effect of methamphetamine on the microglial damage: role of potassium channel Kv1.3.
PLoS ONE,
2014
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69
Dong L
et al.
Potential therapeutic targets for hypoxia-induced pulmonary artery hypertension.
J Transl Med,
2014
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70
Vonderlin N
et al.
Inhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action.
Drug Des Devel Ther,
2014
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71
Pousada G
et al.
Novel mutations in BMPR2, ACVRL1 and KCNA5 genes and hemodynamic parameters in patients with pulmonary arterial hypertension.
PLoS ONE,
2014
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72
Baczkó I
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Characterization of a novel multi-functional resveratrol derivative for the treatment of atrial fibrillation.
Br. J. Pharmacol.,
2013
Sep
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73
Boycott HE
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Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes.
Proc. Natl. Acad. Sci. U.S.A.,
2013
Oct
8
, 110 (E3955-E3964).
74
Olesen MS
et al.
Very early onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation.
Heart Rhythm,
2013
Oct
18
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75
Vallejo-Gracia A
et al.
Emerging role for the voltage-dependent K+ channel Kv1.5 in B-lymphocyte physiology: expression associated with human lymphoma malignancy.
J. Leukoc. Biol.,
2013
Oct
, 94 (779-89).
76
Guo X
et al.
Design and bio-evaluation of indole derivatives as potent Kv1.5 inhibitors.
Bioorg. Med. Chem.,
2013
Nov
1
, 21 (6466-76).
77
Fedele F
et al.
Role of genetic polymorphisms of ion channels in the pathophysiology of coronary microvascular dysfunction and ischemic heart disease.
Basic Res. Cardiol.,
2013
Nov
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78
Leanza L
et al.
Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines.
Curr. Pharm. Des.,
2013
May
16
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79
Christophersen IE
et al.
Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation.
Eur. Heart J.,
2013
May
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80
Zhang RF
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[Long term outcome of atrial fibrillation patients with KCNA5 and NPPA mutations post circumferential pulmonary vein ablation].
Zhonghua Xin Xue Guan Bing Za Zhi,
2013
May
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81
Finlay HJ
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Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.
Bioorg. Med. Chem. Lett.,
2013
Mar
15
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82
Huang H
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Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels.
J. Mol. Cell. Cardiol.,
2013
Jun
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83
Cui Z
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Regulation of the human ether-a-go-go-related gene (hERG) channel by Rab4 protein through neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2).
J. Biol. Chem.,
2013
Jul
26
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84
Ravens U
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Atrial selectivity of antiarrhythmic drugs.
J. Physiol. (Lond.),
2013
Jul
16
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85
Ford J
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Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial Selective Kv1.5/IKur Inhibitor.
J. Cardiovasc. Pharmacol.,
2013
Jan
29
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86
Lang F
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Regulation of ion channels by the serum- and glucocorticoid-inducible kinase SGK1.
FASEB J.,
2013
Jan
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87
Fouillade C
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Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Arterioscler. Thromb. Vasc. Biol.,
2013
Jan
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88
Yang Y
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Specific Kv1.3 blockade modulates key cholesterol-metabolism-associated molecules in human macrophages exposed to ox-LDL.
J. Lipid Res.,
2013
Jan
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89
Olsson RI
et al.
Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5.
Bioorg. Med. Chem. Lett.,
2013
Feb
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90
Jeong I
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Pergolide block of the cloned Kv1.5 potassium channels.
Naunyn Schmiedebergs Arch. Pharmacol.,
2013
Feb
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91
Tikhonov DB
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Homology modeling of Kv1.5 channel block by cationic and electroneutral ligands.
Biochim. Biophys. Acta,
2013
Dec
5
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92
Ishii T
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Sequestosome1/p62: a regulator of redox-sensitive voltage-activated potassium channels, arterial remodeling, inflammation, and neurite outgrowth.
Free Radic. Biol. Med.,
2013
Dec
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93
Wulff H
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Channels: Sticking to nooks and crannies.
Nat. Chem. Biol.,
2013
Aug
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94
Tong M
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Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart.
Biol Rhythm Res,
2013
Aug
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95
Kim SJ
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Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1.
Biochem. J.,
2013
Apr
15
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96
Gao M
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An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure.
Exp Ther Med,
2013
Apr
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97
Mi Y
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The role of potassium channel activation in celecoxib-induced analgesic action.
PLoS ONE,
2013
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98
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A Common Structural Component for β-Subunit Mediated Modulation of Slow Inactivation in Different KV Channels.
Cell. Physiol. Biochem.,
2013
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99
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Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.
PLoS ONE,
2013
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100
Atkinson AJ
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Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.
J Am Heart Assoc,
2013
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101
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New screening system for selective blockers of voltage-gated K(+) channels using recombinant cell lines dying upon single action potential.
J. Pharmacol. Sci.,
2013
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102
Mia S
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Downregulation of Kv1.5 K Channels by the AMP-Activated Protein Kinase.
Cell. Physiol. Biochem.,
2012
Sep
24
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103
Svoboda LK
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Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5.
Circ. Res.,
2012
Sep
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104
Lin CY
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[Cigarette smoke exposure induced pulmonary artery pressure increase through inhibiting Kv1.5 and Kv2.1 mRNA expression in rat pulmonary artery smooth muscles].
Zhonghua Jie He He Hu Xi Za Zhi,
2012
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105
Barber AF
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Novel activation of voltage-gated K(+) channels by sevoflurane.
J. Biol. Chem.,
2012
Nov
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106
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Trafficking of an endogenous potassium channel in adult ventricular myocytes.
Am. J. Physiol., Cell Physiol.,
2012
Nov
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107
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18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels.
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2012
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108
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Differential expression of potassium channels and abnormal conduction in experimental tachycardia-induced heart failure.
Naunyn Schmiedebergs Arch. Pharmacol.,
2012
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109
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Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands.
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2012
Mar
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110
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Kv1.3 Channels Can Modulate Cell Proliferation During Phenotypic Switch by an Ion-Flux Independent Mechanism.
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2012
Mar
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111
Bielanska J
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Differential expression of Kv1.3 and Kv1.5 voltage-dependent K+ channels in human skeletal muscle sarcomas.
Cancer Invest.,
2012
Mar
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112
David M
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Protein kinase C (PKC) activity regulates functional effects of Kvβ1.3 subunit on KV1.5 channels: identification of a cardiac Kv1.5 channelosome.
J. Biol. Chem.,
2012
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113
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Age-dependent changes in ion channel mRNA expression in canine cardiac tissues.
Gen. Physiol. Biophys.,
2012
Jun
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114
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Interactions between the C-terminus of Kv1.5 and Kvβ regulate pyridine nucleotide-dependent changes in channel gating.
Pflugers Arch.,
2012
Jun
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115
Kulzer M
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Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A.
Biochem. Biophys. Res. Commun.,
2012
Jul
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116
Ritchie MD
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Chromosome 4q25 Variants Are Genetic Modifiers of Rare Ion Channel Mutations Associated With Familial Atrial Fibrillation.
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2012
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117
Dai F
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Fluoxetine protects against big endothelin-1 induced anti-apoptosis by rescuing Kv1.5 channels in human pulmonary arterial smooth muscle cells.
Yonsei Med. J.,
2012
Jul
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118
Kim BS
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Argonaute2 regulation for K+ channel-mediated human adipose tissue-derived stromal cells self-renewal and survival in nucleus.
Stem Cells Dev.,
2012
Jul
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119
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Effects of dapoxetine on cloned Kv1.5 channels expressed in CHO cells.
Naunyn Schmiedebergs Arch. Pharmacol.,
2012
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120
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Activation of voltage gated K⁺ channel Kv1.5 by β-catenin.
Biochem. Biophys. Res. Commun.,
2012
Jan
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121
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Extracellular chloride regulation of Kv2.1, contributor to the major outward Kv current in mammalian outer hair cells.
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2012
Jan
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122
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Carvedilol blocks the cloned cardiac Kv1.5 channels in a β-adrenergic receptor-independent manner.
Biochem. Pharmacol.,
2012
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123
Hald BO
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BKCa and KV channels limit conducted vasomotor responses in rat mesenteric terminal arterioles.
Pflugers Arch.,
2012
Feb
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124
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Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport.
Clin. Exp. Nephrol.,
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125
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Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone.
Eur. J. Pharmacol.,
2012
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126
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The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity.
Toxicol In Vitro,
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Endocytic regulation of voltage-dependent potassium channels in the heart.
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Absence of Rgs5 prolongs cardiac repolarization and predisposes to ventricular tachyarrhythmia in mice.
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