TRPML1 Channel

1

Morelli MB et al. Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression.
Oncotarget, 2016 May 27 , ().

2

Cuajungco MP et al. The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function.
Pflugers Arch., 2015 Sep 4 , ().

3

Grishchuk Y et al. Impaired myelination and reduced ferric iron in mucolipidosis IV brain.
Dis Model Mech, 2015 Sep 17 , ().

4

Onyenwoke RU et al. The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase.
Biochem. J., 2015 Sep 15 , 470 (331-42).

5

Lee JH et al. Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.
Cell Rep, 2015 Sep 1 , 12 (1430-44).

6

Dayam RM et al. The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.
Traffic, 2015 Sep , 16 (1010-26).

7

Sun L et al. Novel Role of TRPML2 in the Regulation of the Innate Immune Response.
J. Immunol., 2015 Nov 15 , 195 (4922-32).

8

Cao Q et al. BK Channels Alleviate Lysosomal Storage Diseases by Providing Positive Feedback Regulation of Lysosomal Ca2+ Release.
Dev. Cell, 2015 May 26 , 33 (427-41).

9

Wang W et al. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.
Proc. Natl. Acad. Sci. U.S.A., 2015 Mar 17 , 112 (E1373-81).

10

Miller A et al. Mucolipidosis type IV protein TRPML1-dependent lysosome formation.
Traffic, 2015 Mar , 16 (284-97).

11

Waller-Evans H et al. Regulation of TRPML1 function.
Biochem. Soc. Trans., 2015 Jun , 43 (442-6).

12

Ruas M et al. Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
EMBO J., 2015 Jul 2 , 34 (1743-58).

13

Venkatachalam K et al. The role of TRPMLs in endolysosomal trafficking and function.
Cell Calcium, 2015 Jul , 58 (48-56).

14

Valadez JA et al. PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene.
Gene, 2015 Jan 25 , 555 (194-202).

15

Cheng X et al. The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.
Nat. Med., 2014 Oct , 20 (1187-92).

16

Thieleke-Matos C et al. Host PI(3,5)P2 activity is required for Plasmodium berghei growth during liver stage infection.
Traffic, 2014 Oct , 15 (1066-82).

17

Cuajungco MP et al. Cellular zinc levels are modulated by TRPML1-TMEM163 interaction.
Traffic, 2014 Nov , 15 (1247-65).

18

Coblentz J et al. Loss of TRPML1 promotes production of reactive oxygen species: is oxidative damage a factor in mucolipidosis type IV?
Biochem. J., 2014 Jan 15 , 457 (361-8).

19

Feng X et al. Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.
J. Biol. Chem., 2014 Feb 14 , 289 (4262-72).

20

Feng X et al. Differential mechanisms of action of the mucolipin synthetic agonist, ML-SA1, on insect TRPML and mammalian TRPML1.
Cell Calcium, 2014 Dec , 56 (446-56).

21

Remis NN et al. Mucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaning.
PLoS Genet., 2014 Dec , 10 (e1004833).

22

Bae M et al. Activation of TRPML1 clears intraneuronal Aβ in preclinical models of HIV infection.
J. Neurosci., 2014 Aug 20 , 34 (11485-503).

23

Liu Z et al. A novel role of transient receptor potential mucolipin1 (TRPML1) in protecting against imidazole-induced cytotoxicity.
Biochem. Cell Biol., 2014 Aug , 92 (279-86).

24

García-Añoveros J et al. TRPML2 and mucolipin evolution.
Handb Exp Pharmacol, 2014 , 222 (647-58).

25

Wang W et al. TRPML1: an ion channel in the lysosome.
Handb Exp Pharmacol, 2014 , 222 (631-45).

26

Grimm C et al. TRPML3.
Handb Exp Pharmacol, 2014 , 222 (659-74).

27

Chen CC et al. A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
Nat Commun, 2014 , 5 (4681).

28

Samie M et al. A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.
Dev. Cell, 2013 Sep 16 , 26 (511-24).

29

Venkatachalam K et al. Feast or famine: role of TRPML in preventing cellular amino acid starvation.
Autophagy, 2013 Jan , 9 (98-100).

30

Kukic I et al. Zinc-Dependent Lysosomal Enlargement in TRPML1-Deficient Cells Involves MTF-1 Transcription Factor and ZnT4 (Slc30a4) Transporter.
Biochem. J., 2013 Feb 1 , ().

31

Li X et al. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics.
Proc. Natl. Acad. Sci. U.S.A., 2013 Dec 24 , 110 (21165-70).

32

McCormick NH et al. The Biology of Zinc Transport in Mammary Epithelial Cells: Implications for Mammary Gland Development, Lactation, and Involution.
J Mammary Gland Biol Neoplasia, 2013 Dec 15 , ().

33

Vandewauw I et al. Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse.
BMC Neurosci, 2013 , 14 (21).

34

Spooner E et al. Systematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1.
PLoS ONE, 2013 , 8 (e56780).

35

Benini A et al. Characterization and expression analysis of mcoln1.1 and mcoln1.2, the putative zebrafish co-orthologs of the gene responsible for human mucolipidosis type IV.
Int. J. Dev. Biol., 2013 , 57 (85-93).

36

Wong CO et al. Drosophila TRPML is required for TORC1 activation.
Curr. Biol., 2012 Sep 11 , 22 (1616-21).

37

Weiss N Cross-talk between TRPML1 channel, lipids and lysosomal storage diseases.
Commun Integr Biol, 2012 Mar 1 , 5 (111-3).

38

Zhang X et al. Phosphoinositide isoforms determine compartment-specific ion channel activity.
Proc. Natl. Acad. Sci. U.S.A., 2012 Jul 10 , 109 (11384-9).

39

Colletti GA et al. Loss of the lysosomal ion channel TRPML1 leads to cathepsin B-dependent apoptosis.
, 2012 Jan 18 , ().

40

Dong HW et al. Expression of transient receptor potential (TRP) channel mRNAs in the mouse olfactory bulb.
Neurosci. Lett., 2012 Aug 22 , 524 (49-54).

41

Grimm C et al. ROLE OF TRPML AND TPC CHANNELS IN ENDO-LYSOSOMAL CATION HOMEOSTASIS.
, 2012 Apr 19 , ().

42

Shen D et al. Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release.
Nat Commun, 2012 , 3 (731).

43

Sun T et al. CUP-5, the C. elegans ortholog of the mammalian lysosomal channel protein MLN1/TRPML1, is required for proteolytic degradation in autolysosomes.
Autophagy, 2011 Nov , 7 (1308-15).

44

Yamaguchi S et al. TRPML1 and two-pore channels are functionally independent organellar ion channels.
, 2011 May 3 , ().

45

Kiselyov K et al. TRPML: Transporters of metals in lysosomes essential for cell survival?
, 2011 May 26 , ().

46

Chandra M et al. A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice.
Gastroenterology, 2011 Mar , 140 (857-67).

47

Gilliam JC et al. TRP channel gene expression in the mouse retina.
Vision Res., 2011 Dec 8 , 51 (2440-52).

48

Lloyd-Evans E et al. Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.
Cell Calcium, 2011 Aug , 50 (200-5).

49

Laplante JM et al. The cation channel mucolipin-1 is a bifunctional protein that facilitates membrane remodeling via its serine lipase domain.
Exp. Cell Res., 2011 Apr 1 , 317 (691-705).

50

Bach G et al. Mucolipidosis type IV and the mucolipins.
Biochem. Soc. Trans., 2010 Dec , 38 (1432-5).

51

Dong XP et al. PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.
Nat Commun, 2010 , 1 (38).