Nav1.3

1

Tao H et al. Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels.
Toxicon, 2016 Mar 1 , 111 (13-21).

2

Rogers M et al. Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening.
Assay Drug Dev Technol, 2016 Mar , 14 (109-30).

3

Zhao Y et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord, 2016 , 16 (1).

4

Lin X et al. Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts.
J. Physiol. (Lond.), 2015 Mar 15 , 593 (1389-407).

5

Mishra S et al. Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts.
J. Physiol. (Lond.), 2015 Mar 15 , 593 (1409-27).

6

Gazina EV et al. 'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour.
Hum. Mol. Genet., 2015 Mar 1 , 24 (1457-68).

7

Coronas FI et al. Biochemical and physiological characterization of a new Na(+)-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus.
Peptides, 2015 Jun , 68 (11-6).

8

Cai T et al. Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels.
Peptides, 2015 Jun , 68 (148-56).

9

Torregrosa R et al. Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
Bioorg. Med. Chem., 2015 Jul 1 , 23 (3655-66).

10

Slowik D et al. Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference.
Biochim. Biophys. Acta, 2015 Jul , 1848 (1545-51).

11

Fukuoka T et al. De novo expression of Nav1.7 in injured putative proprioceptive afferents: Multiple tetrodotoxin-sensitive sodium channels are retained in the rat dorsal root after spinal nerve ligation.
Neuroscience, 2015 Jan 22 , 284 (693-706).

12

Lim BC et al. Epilepsy phenotype associated with a chromosome 2q24.3 deletion involving SCN1A: Migrating partial seizures of infancy or atypical Dravet syndrome?
Epilepsy Res., 2015 Jan , 109 (34-9).

13

Li HJ et al. Alteration of Scn3a expression is mediated via CpG methylation and MBD2 in mouse hippocampus during postnatal development and seizure condition.
Biochim. Biophys. Acta, 2015 Jan , 1849 (1-9).

14

Stoetzer C et al. Methadone is a local anaesthetic-like inhibitor of neuronal Na+ channels and blocks excitability of mouse peripheral nerves.
Br J Anaesth, 2015 Jan , 114 (110-20).

15

Zhang F et al. Natural mutations change the affinity of μ-theraphotoxin-Hhn2a to voltage-gated sodium channels.
Toxicon, 2015 Jan , 93 (24-30).

16

Kirchhof P et al. First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart.
Circ Heart Fail, 2015 Jan , 8 (79-88).

17

Vandael DH et al. Reduced availability of voltage-gated sodium channels by depolarization or blockade by tetrodotoxin boosts burst firing and catecholamine release in mouse chromaffin cells.
J. Physiol. (Lond.), 2015 Feb 15 , 593 (905-27).

18

Zhang H et al. Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5.
Mol. Pharmacol., 2015 Feb , 87 (207-17).

19

Cardoso FC et al. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol. Pharmacol., 2015 Aug , 88 (291-303).

20

Hong H et al. Isobaric Tags for Relative and Absolute Quantitation-Based Proteomic Analysis of Patent and Constricted Ductus Arteriosus Tissues Confirms the Systemic Regulation of Ductus Arteriosus Closure.
J. Cardiovasc. Pharmacol., 2015 Aug , 66 (204-13).

21

Pucca MB et al. Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages.
Biochimie, 2015 Aug , 115 (8-16).

22

Guo F et al. Low-Mg(2+) treatment increases sensitivity of voltage-gated Na(+) channels to Ca(2+)/calmodulin-mediated modulation in cultured hippocampal neurons.
Am. J. Physiol., Cell Physiol., 2015 Apr 15 , 308 (C594-605).

23

Salunkhe VA et al. Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells.
Acta Physiol (Oxf), 2015 Apr , 213 (882-92).

24

Tan AM et al. Virus-Mediated Knockdown of Nav1.3 in Dorsal Root Ganglia of STZ-Induced Diabetic Rats Alleviates Tactile Allodynia.
Mol. Med., 2015 , 21 (544-52).

25

Chen YJ et al. Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.
Mol. Neurobiol., 2015 , 51 (1263-70).

26

Tang C et al. Synergetic action of domain II and IV underlies persistent current generation in Nav1.3 as revealed by a tarantula toxin.
Sci Rep, 2015 , 5 (9241).

27

Camargos TS et al. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.
PLoS ONE, 2015 , 10 (e0128578).

28

Habib AM et al. Sodium channels and pain.
Handb Exp Pharmacol, 2015 , 227 (39-56).

29

Kharatmal SB et al. Voltage-Gated Sodium Channels as Therapeutic Targets for Treatment of Painful Diabetic Neuropathy.
Mini Rev Med Chem, 2015 , 15 (1134-47).

30

Chen W et al. Tumor necrosis factor-α enhances voltage-gated Na⁺ currents in primary culture of mouse cortical neurons.
J Neuroinflammation, 2015 , 12 (126).

31

Ding T et al. Neural tissue engineering scaffold with sustained RAPA release relieves neuropathic pain in rats.
Life Sci., 2014 Sep 1 , 112 (22-32).

32

Green BR et al. Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity.
Future Med Chem, 2014 Oct , 6 (1677-98).

33

Dhalla AK et al. Blockade of Na+ channels in pancreatic α-cells has antidiabetic effects.
Diabetes, 2014 Oct , 63 (3545-56).

34

Zhang Q et al. Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.
J. Physiol. (Lond.), 2014 Nov 1 , 592 (4677-96).

35

Gilchrist J et al. Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents.
ACS Chem. Biol., 2014 May 16 , 9 (1204-12).

36

Lin CR et al. Intrathecal miR-183 delivery suppresses mechanical allodynia in mononeuropathic rats.
Eur. J. Neurosci., 2014 May , 39 (1682-9).

37

Baum L et al. Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.
Hum. Genet., 2014 May , 133 (651-9).

38

Zhang YY et al. Characterization of functional ion channels in human cardiac c-kit+ progenitor cells.
Basic Res. Cardiol., 2014 May , 109 (407).

39

Zidar N et al. Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators.
Eur J Med Chem, 2014 Mar 3 , 74 (23-30).

40

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

41

Minett MS et al. Pain without nociceptors? Nav1.7-independent pain mechanisms.
Cell Rep, 2014 Jan 30 , 6 (301-12).

42

Baroni D et al. Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression.
Biol. Cell, 2014 Jan , 106 (13-29).

43

Chen HP et al. Intrathecal miR-96 inhibits Nav1.3 expression and alleviates neuropathic pain in rat following chronic construction injury.
Neurochem. Res., 2014 Jan , 39 (76-83).

44

Huang XJ et al. Blockage of the upregulation of voltage-gated sodium channel nav1.3 improves outcomes after experimental traumatic brain injury.
J. Neurotrauma, 2014 Feb 15 , 31 (346-57).

45

Cheng KI et al. Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P-p38 mitogen-activated protein kinase activation in streptozotocin-induced diabetic rats.
Eur J Pain, 2014 Feb , 18 (162-73).

46

Vanoye CG et al. Novel SCN3A variants associated with focal epilepsy in children.
Neurobiol. Dis., 2014 Feb , 62 (313-22).

47

Lin X et al. Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts.
J. Physiol. (Lond.), 2014 Aug 15 , ().

48

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

49

Black JA et al. Noncanonical roles of voltage-gated sodium channels.
Neuron, 2013 Oct 16 , 80 (280-91).

50

Westenbroek RE et al. Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry.
J. Mol. Cell. Cardiol., 2013 Nov , 64 (69-78).

51

McCormack K et al. Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jul 16 , 110 (E2724-32).

52

Xu X et al. Abnormal changes in voltage-gated sodium channels Na(V)1.1, Na(V)1.2, Na(V)1.3, Na(V)1.6 and in calmodulin/calmodulin-dependent protein kinase II, within the brains of spontaneously epileptic rats and tremor rats.
Brain Res. Bull., 2013 Jul , 96 (1-9).

53

Haerian BS et al. SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.
Pharmacogenomics, 2013 Jul , 14 (1153-66).

54

Huang XJ et al. Expression of voltage-gated sodium channel Nav1.3 is associated with severity of traumatic brain injury in adult rats.
J. Neurotrauma, 2013 Jan 1 , 30 (39-46).

55

Celle ME et al. Interstitial 2q24.3 deletion including SCN2A and SCN3A genes in a patient with autistic features, psychomotor delay, microcephaly and no history of seizures.
Gene, 2013 Dec 15 , 532 (294-6).

56

Dustrude ET et al. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
J. Biol. Chem., 2013 Aug 23 , 288 (24316-31).

57

Bradley E et al. The cardiac sodium current Na(v)1.5 is functionally expressed in rabbit bronchial smooth muscle cells.
Am. J. Physiol., Cell Physiol., 2013 Aug 15 , 305 (C427-35).

58

Kaufmann SG et al. Distribution and function of sodium channel subtypes in human atrial myocardium.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (133-41).

59

Kuang Z et al. Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency.
ACS Chem. Biol., 2013 , 8 (1344-51).

60

Zhou X et al. Modulation of mononuclear phagocyte inflammatory response by liposome-encapsulated voltage gated sodium channel inhibitor ameliorates myocardial ischemia/reperfusion injury in rats.
PLoS ONE, 2013 , 8 (e74390).

61

Yu S et al. Upregulated expression of voltage-gated sodium channel Nav1.3 in cortical lesions of patients with focal cortical dysplasia type IIb.
Neuroreport, 2012 May 9 , 23 (407-11).

62

Hodgdon KE et al. Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Neuroscience, 2012 Mar 29 , 206 (237-44).

63

Liu ZR et al. Pharmacological kinetics of BmK AS, a sodium channel site 4-specific modulator on Nav1.3.
Neurosci Bull, 2012 Jun , 28 (209-21).

64

Liu P et al. Modulation of neuronal sodium channels by the sea anemone peptide BDS-I.
J. Neurophysiol., 2012 Jun , 107 (3155-67).

65

Leffler A et al. Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine.
Anesthesiology, 2012 Jun , 116 (1335-46).

66

Kim HG et al. Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies.
Am. J. Hum. Genet., 2012 Jul 13 , 91 (56-72).

67

Fukuoka T et al. Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation.
Pain, 2012 Jan , 153 (68-79).

68

Goeggel Simonetti B et al. Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.
Epilepsia, 2012 Dec , 53 (2128-34).

69

Shi X et al. Clinical spectrum of SCN2A mutations.
Brain Dev., 2012 Aug , 34 (541-5).

70

Byers MR et al. Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels.
Arch. Oral Biol., 2011 Nov , 56 (1199-220).

71

Shou WT et al. [Role of voltage-sodium channels in neuropathic pain].
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2011 Mar , 40 (217-21).

72

Deng GF et al. Promoter analysis of mouse Scn3a gene and regulation of the promoter activity by GC box and CpG methylation.
J. Mol. Neurosci., 2011 Jun , 44 (115-21).

73

Okumura A et al. Refractory neonatal epilepsy with a de novo duplication of chromosome 2q24.2q24.3.
Epilepsia, 2011 Jul , 52 (e66-9).

74

Widmark J et al. Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.
Mol. Biol. Evol., 2011 Jan , 28 (859-71).

75

Baroni D et al. Molecular differential expression of voltage-gated sodium channel α and β subunit mRNAs in five different mammalian cell lines.
J. Bioenerg. Biomembr., 2011 Dec , 43 (729-38).

76

Vecchi M et al. Infantile epilepsy associated with mosaic 2q24 duplication including SCN2A and SCN3A.
Seizure, 2011 Dec , 20 (813-6).

77

Bartnik M et al. Disruption of the SCN2A and SCN3A genes in a patient with mental retardation, neurobehavioral and psychiatric abnormalities, and a history of infantile seizures.
Clin. Genet., 2011 Aug , 80 (191-5).

78

Raymond G et al. An interstitial duplication at 2q24.3 involving the SCN1A, SCN2A, SCN3A genes associated with infantile epilepsy.
Am. J. Med. Genet. A, 2011 Apr , 155A (920-3).

79

Hildebrand ME et al. Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons.
Mol Pain, 2011 , 7 (67).

80

Mo G et al. Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C.
Mol Pain, 2011 , 7 (14).

81

Cheng KI et al. Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav1.3 expression and decreasing spinal microglial activation.
BMC Neurol, 2011 , 11 (71).

82

Chen CP et al. Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.
Eur J Med Genet, 2010 Jul-Aug , 53 (217-20).

83

He H et al. Molecular determination of selectivity of the site 3 modulator (BmK I) to sodium channels in the CNS: a clue to the importance of Nav1.6 in BmK I-induced neuronal hyperexcitability.
Biochem. J., 2010 Sep 28 , 431 (289-98).

84

Fukuoka T et al. Laminae-specific distribution of alpha-subunits of voltage-gated sodium channels in the adult rat spinal cord.
Neuroscience, 2010 Sep 1 , 169 (994-1006).

85

Heron SE et al. Familial neonatal seizures with intellectual disability caused by a microduplication of chromosome 2q24.3.
Epilepsia, 2010 Sep , 51 (1865-9).

86

He XH et al. TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury.
Pain, 2010 Nov , 151 (266-79).

87

Gao R et al. Expression of voltage-gated sodium channel alpha subunit in human ovarian cancer.
Oncol. Rep., 2010 May , 23 (1293-9).

88

Gazina EV et al. Differential expression of exon 5 splice variants of sodium channel alpha subunit mRNAs in the developing mouse brain.
Neuroscience, 2010 Mar 10 , 166 (195-200).

89

Black JA et al. Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5.
Brain, 2010 Mar , 133 (835-46).

90

Meisler MH et al. Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects.
J. Physiol. (Lond.), 2010 Jun 1 , 588 (1841-8).

91

Cusdin FS et al. The sodium channel {beta}3-subunit induces multiphasic gating in Nav1.3 and affects fast inactivation via distinct intracellular regions.
, 2010 Jul 30 , ().

92

Zang Y et al. Inhibition of NF-kappaB prevents mechanical allodynia induced by spinal ventral root transection and suppresses the re-expression of Nav1.3 in DRG neurons in vivo and in vitro.
Brain Res., 2010 Dec 2 , 1363 (151-8).

93

Estacion M et al. A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons.
Exp. Neurol., 2010 Aug , 224 (362-8).

94

Ohno K et al. Altered expression of sodium channel distribution in the dorsal root ganglion after gradual elongation of rat sciatic nerves.
J. Orthop. Res., 2010 Apr , 28 (481-6).

95

Tan J et al. Human and rat Nav1.3 voltage-gated sodium channels differ in inactivation properties and sensitivity to the pyrethroid insecticide tefluthrin.
Neurotoxicology, 2009 Jan , 30 (81-9).

96

Siqueira SR et al. Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.
Neuroscience, 2009 Dec 1 , 164 (573-7).

97

Black JA et al. Sodium channel activity modulates multiple functions in microglia.
Glia, 2009 Aug 1 , 57 (1072-81).

98

Xi Y et al. Increased late sodium currents are related to transcription of neuronal isoforms in a pressure-overload model.
Eur. J. Heart Fail., 2009 Aug , 11 (749-57).

99

Thakor DK et al. Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy.
, 2009 , 5 (14).

100

Gao N et al. Voltage-gated sodium channels in taste bud cells.
, 2009 , 10 (20).

101

Pinto FM et al. Molecular and functional characterization of voltage-gated sodium channels in human sperm.
Reprod. Biol. Endocrinol., 2009 , 7 (71).

102

Fukuoka T et al. Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons.
J. Comp. Neurol., 2008 Sep 10 , 510 (188-206).

103

Xiao Y et al. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration.
J. Biol. Chem., 2008 Oct 3 , 283 (27300-13).

104

Xu Q et al. Deglycosylation altered the gating properties of rNav1.3: glycosylation/deglycosylation homeostasis probably complicates the functional regulation of voltage-gated sodium channel.
, 2008 Oct , 24 (283-7).

105

Kwan P et al. Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.
Pharmacogenet. Genomics, 2008 Nov , 18 (989-98).

106

Holland KD et al. Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy.
Neurosci. Lett., 2008 Mar 5 , 433 (65-70).

107

Dray A Neuropathic pain: emerging treatments.
, 2008 Jul , 101 (48-58).

108

Guo F et al. Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat.
Brain Res. Bull., 2008 Jan 31 , 75 (179-87).

109

Krafte DS et al. Sodium channels and nociception: recent concepts and therapeutic opportunities.
, 2008 Feb , 8 (50-6).

110

Black JA et al. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.
Ann. Neurol., 2008 Dec , 64 (644-53).

111

Huang HL et al. Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves.
, 2008 , 4 (33).

112

Kaneko Y et al. Expression of Nav1.1 in rat retinal AII amacrine cells.
Neurosci. Lett., 2007 Sep 7 , 424 (83-8).

113

Seda M et al. Functional and molecular characterization of voltage-gated sodium channels in uteri from nonpregnant rats.
Biol. Reprod., 2007 Nov , 77 (855-63).

114

Fry M et al. Differentiated pattern of sodium channel expression in dissociated Purkinje neurons maintained in long-term culture.
J. Neurochem., 2007 May , 101 (737-48).

115

Du Y et al. Downregulation of neuronal sodium channel subunits Nav1.1 and Nav1.6 in the sinoatrial node from volume-overloaded heart failure rat.
Pflugers Arch., 2007 Jun , 454 (451-9).

116

Lee-Kwon W et al. Vasa recta voltage-gated Na+ channel Nav1.3 is regulated by calmodulin.
Am. J. Physiol. Renal Physiol., 2007 Jan , 292 (F404-14).

117

Huang X et al. [Expression and function of voltage-gated Na+ channel isoforms in rat sinoatrial node]
Nan Fang Yi Ke Da Xue Xue Bao, 2007 Jan , 27 (52-5).

118

Martin MS et al. The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.
Hum. Mol. Genet., 2007 Dec 1 , 16 (2892-9).

119

Martin MS et al. Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.
Genomics, 2007 Aug , 90 (225-35).

120

Wang YW et al. Modulatory effect of auxiliary beta1 subunit on Nav1.3 voltage-gated sodium channel expressed in Xenopus oocyte.
Chin. Med. J., 2007 Apr 20 , 120 (721-3).

121

Hains BC et al. Sodium channel expression and the molecular pathophysiology of pain after SCI.
Prog. Brain Res., 2007 , 161 (195-203).

122

Rogers M et al. The role of sodium channels in neuropathic pain.
Semin. Cell Dev. Biol., 2006 Oct , 17 (571-81).

123

Lampert A et al. Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.
, 2006 Oct , 174 (660-6).

124

Maertens C et al. Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae.
Mol. Pharmacol., 2006 Jul , 70 (405-14).

125

Jarnot M et al. Immunolocalization of NaV1.2 channel subtypes in rat and cat brain and spinal cord with high affinity antibodies.
Brain Res., 2006 Aug 30 , 1107 (1-12).

126

Waxman SG et al. Fire and phantoms after spinal cord injury: Na+ channels and central pain.
Trends Neurosci., 2006 Apr , 29 (207-15).

127

Nassar MA et al. Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.
, 2006 , 2 (33).

128

Zhao P et al. Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury.
, 2006 , 2 (27).

129

Ebensperger G et al. Fetal brain hypometabolism during prolonged hypoxaemia in the llama.
J. Physiol. (Lond.), 2005 Sep 15 , 567 (963-75).

130

Lindia JA et al. Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats.
Pain, 2005 Sep , 117 (145-53).

131

Hains BC et al. Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury.
Brain, 2005 Oct , 128 (2359-71).

132

Mulley JC et al. SCN1A mutations and epilepsy.
Hum. Mutat., 2005 Jun , 25 (535-42).

133

Rush AM et al. Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.
Eur. J. Neurosci., 2005 Jul , 22 (39-49).

134

Thimmapaya R et al. Distribution and functional characterization of human Nav1.3 splice variants.
Eur. J. Neurosci., 2005 Jul , 22 (1-9).

135

Mechaly I et al. Molecular diversity of voltage-gated sodium channel alpha subunits expressed in neuronal and non-neuronal excitable cells.
Neuroscience, 2005 , 130 (389-96).

136

Lei M et al. Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking.
J. Physiol. (Lond.), 2004 Sep 15 , 559 (835-48).

137

Wood JN et al. Voltage-gated sodium channels and pain pathways.
J. Neurobiol., 2004 Oct , 61 (55-71).

138

Leipold E et al. Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.
Mol. Pharmacol., 2004 Mar , 65 (685-91).

139

Casula MA et al. Expression of the sodium channel beta3 subunit in injured human sensory neurons.
Neuroreport, 2004 Jul 19 , 15 (1629-32).

140

Barbier J et al. A delta-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles.
J. Biol. Chem., 2004 Feb 6 , 279 (4680-5).

141

Oliveira JS et al. Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.
J. Biol. Chem., 2004 Aug 6 , 279 (33323-35).

142

Shah BS et al. Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface.
J. Neurosci., 2004 Aug 18 , 24 (7387-99).

143

Chung JM et al. Sodium channels and neuropathic pain.
Novartis Found. Symp., 2004 , 261 (19-27; discussion 27-31, 47-54).

144

Klein JP et al. Patterned electrical activity modulates sodium channel expression in sensory neurons.
J. Neurosci. Res., 2003 Oct 15 , 74 (192-8).

145

Hains BC et al. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury.
J. Neurosci., 2003 Oct 1 , 23 (8881-92).

146

Craner MJ et al. Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination.
Brain, 2003 Jul , 126 (1552-61).

147

Weiss LA et al. Sodium channels SCN1A, SCN2A and SCN3A in familial autism.
Mol. Psychiatry, 2003 Feb , 8 (186-94).

148

Schroeder K et al. Ionworks HT: a new high-throughput electrophysiology measurement platform.
, 2003 Feb , 8 (50-64).

149

Vega AV et al. L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.
Brain Res. Mol. Brain Res., 2003 Aug 19 , 116 (115-25).

150

Lenkowski PW et al. Lidocaine block of neonatal Nav1.3 is differentially modulated by co-expression of beta1 and beta3 subunits.
Eur. J. Pharmacol., 2003 Apr 25 , 467 (23-30).

151

Schaller KL et al. Expression and distribution of voltage-gated sodium channels in the cerebellum.
Cerebellum, 2003 , 2 (2-9).

152

Alessandri-Haber N et al. Molecular determinants of emerging excitability in rat embryonic motoneurons.
J. Physiol. (Lond.), 2002 May 15 , 541 (25-39).

153

Meadows LS et al. Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits.
Neuroscience, 2002 , 114 (745-53).

154

Kasai N et al. Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.
Gene, 2001 Feb 7 , 264 (113-22).

155

Cummins TR et al. Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons.
J. Neurosci., 2001 Aug 15 , 21 (5952-61).

156

Shah BS et al. Developmental expression of the novel voltage-gated sodium channel auxiliary subunit beta3, in rat CNS.
J. Physiol. (Lond.), 2001 Aug 1 , 534 (763-76).

157

Baulac S et al. A second locus for familial generalized epilepsy with febrile seizures plus maps to chromosome 2q21-q33.
Am. J. Hum. Genet., 1999 Oct , 65 (1078-85).

158

Lu CM et al. Isolation of a human-brain sodium-channel gene encoding two isoforms of the subtype III alpha-subunit.
J. Mol. Neurosci., 1998 Feb , 10 (67-70).

159

Beckers MC et al. A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.
Genomics, 1996 Aug 15 , 36 (202-5).

160

Malo MS et al. Targeted gene walking by low stringency polymerase chain reaction: assignment of a putative human brain sodium channel gene (SCN3A) to chromosome 2q24-31.
Proc. Natl. Acad. Sci. U.S.A., 1994 Apr 12 , 91 (2975-9).

161

Malo D et al. Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.
Genomics, 1991 Jul , 10 (666-72).