ClIC1

Description: chloride intracellular channel 1
Gene: Clic1
Alias: clic1

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	1192	6	6737
Mouse	114584	17	8476
Rat	406864	20	8844

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_001287593.1	1574
Mouse	NM_033444.2	1159
Rat	NM_001002807.2	1200

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	O00299	241
Mouse	Q9Z1Q5	241
Rat	Q6MG61	241

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NM_001287593.1

1574

NP_001274522.1

241

transcript variant 1

NM_001287594.3

1085

NP_001274523.1

241

transcript variant 3

NM_001288.6

1199

NP_001279.2

241

transcript variant 2

Known

NM_001002807.2

1200

NP_001002807.1

241

Predicted

XM_039098950.1

1002

XP_038954878.1

240

transcript variant X1

isoform X1

XM_039098951.1

1368

XP_038954879.1

210

transcript variant X2

isoform X2

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Post-Translational Modifications

PTM

Position

Type

Modified residue

N-acetylalanine

Modified residue

N6-acetyllysine

Modified residue

S-glutathionyl cysteine; alternate

Modified residue

119

N6-acetyllysine

Modified residue

121

Phosphoserine

Modified residue

131

N6-acetyllysine

Modified residue

156

Phosphoserine

Modified residue

211

Phosphoserine

Modified residue

233

Phosphotyrosine

Disulfide bond

Alternate

Modified residue

N-acetylalanine

Modified residue

N6-acetyllysine

Modified residue

119

N6-acetyllysine

Modified residue

121

Phosphoserine

Modified residue

131

N6-acetyllysine

Modified residue

156

Phosphoserine

Modified residue

211

Phosphoserine

Modified residue

233

Phosphotyrosine

Disulfide bond

Modified residue

N-acetylalanine

Modified residue

N6-acetyllysine

Modified residue

119

N6-acetyllysine

Modified residue

121

Phosphoserine

Modified residue

131

N6-acetyllysine

Modified residue

156

Phosphoserine

Modified residue

211

Phosphoserine

Modified residue

233

Phosphotyrosine

Disulfide bond

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Structure

ClIC1 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	1659.58	source
Mouse	1890.21	source
Rat	1653.99	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/116/ , accessed on 2024 Nov 21

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