SK4

1

Vaidyanathan R et al. IK1-enhanced human-induced pluripotent stem cell-derived cardiomyocytes: an improved cardiomyocyte model to investigate inherited arrhythmia syndromes.
Am. J. Physiol. Heart Circ. Physiol., 2016 Jun 1 , 310 (H1611-21).

2

Olamendi-Portugal T et al. Isolation, chemical and functional characterization of several new K(+)-channel blocking peptides from the venom of the scorpion Centruroides tecomanus.
Toxicon, 2016 Jun 1 , 115 (1-12).

3

van der Heyden MA et al. Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation.
Eur. J. Pharmacol., 2016 Jan 15 , 771 (56-64).

4

Yin MZ et al. Activation of K(+) channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca(2+) ionophore-induced cell death.
Korean J. Physiol. Pharmacol., 2016 Jan , 20 (25-33).

5

Pethő Z et al. The anti-proliferative effect of cation channel blockers in T lymphocytes depends on the strength of mitogenic stimulation.
Immunol. Lett., 2016 Feb 6 , 171 (60-69).

6

Raychaudhuri SK et al. KCa3.1(-/-) Mice Do Not Develop CIA: Regulatory Role for KCa3.1 in Autoimmune Arthritis.
J. Cell. Physiol., 2016 Feb 22 , ().

7

Choi JY et al. Role of protein kinase A and class II phosphatidylinositol 3-kinase C2β in the downregulation of KCa3.1 channel synthesis and membrane surface expression by lyso-globotriaosylceramide.
Biochem. Biophys. Res. Commun., 2016 Feb 19 , 470 (907-12).

8

Mattheij NJ et al. Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
FASEB J., 2016 Feb , 30 (727-37).

9

D'Alessandro G et al. KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment.
Oncotarget, 2016 Apr 16 , ().

10

Ohya S et al. Downregulation of the Ca(2+)-activated K(+) channel KC a3.1 by histone deacetylase inhibition in human breast cancer cells.
Pharmacol Res Perspect, 2016 Apr , 4 (e00228).

11

Ohya S Physiological Role of K(+) Channels in the Regulation of T Cell Function.
Yakugaku Zasshi, 2016 , 136 (479-83).

12

Cubeddu LX Drug-induced Inhibition and Trafficking Disruption of ion Channels: Pathogenesis of QT Abnormalities and Drug-induced Fatal Arrhythmias.
Curr Cardiol Rev, 2016 , 12 (141-54).

13

Ye F et al. The Scorpion Toxin Analogue BmKTX-D33H as a Potential Kv1.3 Channel-Selective Immunomodulator for Autoimmune Diseases.
Toxins (Basel), 2016 , 8 ().

14

Siddiqui TA et al. Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia.
J Neuroinflammation, 2016 , 13 (66).

15

Williams G et al. A web portal for in-silico action potential predictions.
J Pharmacol Toxicol Methods, 2015 Sep-Oct , 75 (10-6).

16

Goedicke-Fritz S et al. Evidence for functional and dynamic microcompartmentation of Cav-1/TRPV4/K(Ca) in caveolae of endothelial cells.
Eur. J. Cell Biol., 2015 Jul-Sep , 94 (391-400).

17

Bhuyan R et al. Molecular dynamics of Kv1.3 ion channel and structural basis of its inhibition by scorpion toxin-OSK1 derivatives.
Biophys. Chem., 2015 Aug-Sep , 203-204 (1-11).

18

Bulk E et al. Epigenetic dysregulation of KCa 3.1 channels induces poor prognosis in lung cancer.
Int. J. Cancer, 2015 Sep 15 , 137 (1306-17).

19

Yan ZY et al. Na+-induced Ca2+ influx through reverse mode of Na+-Ca2+ exchanger in mouse ventricular cardiomyocyte.
Oncotarget, 2015 Sep 15 , 6 (23272-80).

20

Glogowska E et al. Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis.
Blood, 2015 Sep 10 , 126 (1281-4).

21

Rapetti-Mauss R et al. A mutation in the Gardos channel is associated with hereditary xerocytosis.
Blood, 2015 Sep 10 , 126 (1273-80).

22

Zhang SX et al. [Effect of Kv1.3 and KCa3.1 potassium ion channels on the proliferation and migration of monocytes/macrophages].
Sheng Li Xue Bao, 2015 Oct 25 , 67 (505-12).

23

Andolfo I et al. Novel Gardos channel mutations linked to dehydrated hereditary stomatocytosis (xerocytosis).
Am. J. Hematol., 2015 Oct , 90 (921-6).

24

Abramochkin DV et al. Effects of new class III antiarrhythmic drug niferidil on electrical activity in murine ventricular myocardium and their ionic mechanisms.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Oct , 388 (1105-12).

25

Kollár S et al. Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes.
Oncotarget, 2015 May 30 , 6 (13750-6).

26

Myles RC et al. Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart.
J. Physiol. (Lond.), 2015 Mar 15 , 593 (1479-93).

27

Deng Y et al. Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice.
Eur. J. Pharmacol., 2015 Mar 11 , ().

28

Ma SF et al. H2S targets the Cys320/Cys529 motif in Kv4.2 to inhibit the Ito potassium channels in cardiomyocytes and regularizes fatal arrhythmia in myocardial infarction.
Antioxid. Redox Signal., 2015 Mar 10 , ().

29

Dominguez Rieg JA et al. P2Y₂ receptor activation decreases blood pressure via intermediate conductance potassium channels and connexin 37.
Acta Physiol (Oxf), 2015 Mar , 213 (628-41).

30

Li X et al. Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2.
Cardiovasc Drugs Ther, 2015 Jun , 29 (209-18).

31

Chang SC et al. N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.
FEBS J., 2015 Jun , 282 (2247-59).

32

Henríquez C et al. The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils.
Acta Physiol (Oxf), 2015 Jul 3 , ().

33

Friebel K et al. Functional role of the KCa3.1 potassium channel in synovial fibroblasts from rheumatoid arthritis patients.
J. Cell. Physiol., 2015 Jul , 230 (1677-88).

34

Cordeiro JM et al. Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.
J. Mol. Cell. Cardiol., 2015 Jul , 84 (52-60).

35

Mishra RC et al. Inhibition of Myogenic Tone in Rat Cremaster and Cerebral Arteries by SKA-31, an Activator of Endothelial KCa2.3 and KCa3.1 Channels.
J. Cardiovasc. Pharmacol., 2015 Jul , 66 (118-27).

36

Huang C et al. KCa3.1: a new player in progressive kidney disease.
Curr. Opin. Nephrol. Hypertens., 2015 Jan , 24 (61-6).

37

Váczi K et al. 9-Anthracene carboxylic acid is more suitable than DIDS for characterization of calcium-activated chloride current during canine ventricular action potential.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Jan , 388 (87-100).

38

Gillet L et al. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current.
Heart Rhythm, 2015 Jan , 12 (181-92).

39

Chen YJ et al. Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke.
Stroke, 2015 Jan , 46 (237-44).

40

Qi XY et al. Fibroblast inward-rectifier potassium current upregulation in profibrillatory atrial remodeling.
Circ. Res., 2015 Feb 27 , 116 (836-45).

41

Long VP et al. Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling.
Life Sci., 2015 Feb 15 , 123 (61-71).

42

Turner RW et al. Neuronal expression of the intermediate conductance calcium-activated potassium channel KCa3.1 in the mammalian central nervous system.
Pflugers Arch., 2015 Feb , 467 (311-28).

43

Littlechild R et al. Inhibition of KCa3.1 by depolarisation and 2-aminoethoxydiphenyl borate (2-APB) during Ca²⁺ release activated Ca²⁺ (CRAC) entry in human erythroleukemia (HEL) cells: Implications for the interpretation of 2-APB inhibition of CRAC entry.
Cell Calcium, 2015 Feb , 57 (76-88).

44

Gasparoli L et al. New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Mol. Pharmacol., 2015 Feb , 87 (183-96).

45

Oliván-Viguera A et al. A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.
Mol. Pharmacol., 2015 Feb , 87 (338-48).

46

Choi JY et al. Lyso-globotriaosylceramide downregulates KCa3.1 channel expression to inhibit collagen synthesis in fibroblasts.
Biochem. Biophys. Res. Commun., 2015 Dec 25 , 468 (883-8).

47

Alonso H et al. Thyroid stimulating hormone directly modulates cardiac electrical activity.
J. Mol. Cell. Cardiol., 2015 Dec , 89 (280-6).

48

Zhou XB et al. Nucleoside diphosphate kinase B-activated intermediate conductance potassium channels are critical for neointima formation in mouse carotid arteries.
Arterioscler. Thromb. Vasc. Biol., 2015 Aug , 35 (1852-61).

49

Zúñiga-García V et al. Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.
Dig. Dis. Sci., 2015 Apr 5 , ().

50

Huang Y et al. [Combined transgenic inhibition of CaMKII and Ik1 on cardiac remodeling].
Sheng Li Xue Bao, 2015 Apr 25 , 67 (201-6).

51

Freise C et al. K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells.
Liver Int., 2015 Apr , 35 (1244-52).

52

Waeckel L et al. Preserved regulation of renal perfusion pressure by small and intermediate conductance KCa channels in hypertensive mice with or without renal failure.
Pflugers Arch., 2015 Apr , 467 (817-31).

53

Penna A et al. KCa3.1-Dependent Hyperpolarization Enhances Intracellular Ca2+ Signaling Induced by fMLF in Differentiated U937 Cells.
PLoS ONE, 2015 , 10 (e0139243).

54

Saito Y et al. Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.
PLoS ONE, 2015 , 10 (e0138193).

55

Ju CH et al. Blockade of KCa3.1 Attenuates Left Ventricular Remodeling after Experimental Myocardial Infarction.
Cell. Physiol. Biochem., 2015 , 36 (1305-15).

56

Cahalan SM et al. Piezo1 links mechanical forces to red blood cell volume.
Elife, 2015 , 4 ().

57

Rabjerg M et al. High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.
PLoS ONE, 2015 , 10 (e0122992).

58

Kudryashova NN et al. Conditions for Waveblock Due to Anisotropy in a Model of Human Ventricular Tissue.
PLoS ONE, 2015 , 10 (e0141832).

59

Thireau J et al. ACE Inhibitor Delapril Prevents Ca(2+)-Dependent Blunting of IK1 and Ventricular Arrhythmia in Ischemic Heart Disease.
Curr. Mol. Med., 2015 , 15 (642-51).

60

Lin H et al. Lentiviral shRNA against KCa3.1 inhibits allergic response in allergic rhinitis and suppresses mast cell activity via PI3K/AKT signaling pathway.
Sci Rep, 2015 , 5 (13127).

61

Nakamura K et al. Proinflammatory Cytokines and Potassium Channels in the Kidney.
Mediators Inflamm., 2015 , 2015 (362768).

62

Arthur GK et al. KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells.
PLoS ONE, 2015 , 10 (e0145259).

63

Duffy SM et al. Orai/CRACM1 and KCa3.1 ion channels interact in the human lung mast cell plasma membrane.
Cell Commun. Signal, 2015 , 13 (32).

64

Sun J et al. Microelectrode array measurement of potassium ion channel remodeling on the field action potential duration in rapid atrial pacing rabbits model.
Int J Clin Exp Med, 2015 , 8 (249-56).

65

Meijer van Putten RM et al. Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.
Front Physiol, 2015 , 6 (7).

66

Zhang Y et al. Effects of the venom of the spider Ornithoctonus hainana on neonatal rat ventricular myocytes cellular and ionic electrophysiology.
Toxicon, 2014 Sep , 87 (104-12).

67

Asakura K et al. EAD and DAD mechanisms analyzed by developing a new human ventricular cell model.
Prog. Biophys. Mol. Biol., 2014 Sep , 116 (11-24).

68

Ongerth T et al. Targeting of microglial KCa3.1 channels by TRAM-34 exacerbates hippocampal neurodegeneration and does not affect ictogenesis and epileptogenesis in chronic temporal lobe epilepsy models.
Eur. J. Pharmacol., 2014 Oct 5 , 740 (72-80).

69

Xu B et al. Alternations of cardiac IK1 and Ito from FKBP12.6 transgenic mouse heart and potential impact of cardiac hypertrophy.
Int. J. Cardiol., 2014 Oct 20 , 176 (1017-20).

70

Wong R et al. PKA reduces the rat and human KCa3.1 current, CaM binding, and Ca2+ signaling, which requires Ser332/334 in the CaM-binding C terminus.
J. Neurosci., 2014 Oct 1 , 34 (13371-83).

71

Kharche SR et al. Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of atrial fibrillation: a computer simulation.
Europace, 2014 Oct , 16 (1524-33).

72

Huang C et al. Role of the potassium channel KCa3.1 in diabetic nephropathy.
Clin. Sci., 2014 Oct , 127 (423-33).

73

Liu CF et al. Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction.
J. Cardiovasc. Pharmacol., 2014 Oct , 64 (345-56).

74

Wu BW et al. On the risk concerns of zacopride, a moderate IK1 channel agonist with cardiac protective action.
J. Cardiovasc. Pharmacol., 2014 Oct , 64 (357-9).

75

Curtis MJ Activation of IK1 by zacopride: amelioration of left ventricular remodeling, but at what risk?
J. Cardiovasc. Pharmacol., 2014 Oct , 64 (343-4).

76

Chen R et al. Mechanisms and energetics of potassium channel block by local anesthetics and antifungal agents.
Biochemistry, 2014 Nov 4 , 53 (6786-92).

77

Haworth TE et al. Electrical excitability of the heart in a Chondrostei fish, the Siberian sturgeon (Acipenser baerii).
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2014 Nov 1 , 307 (R1157-66).

78

Gómez R et al. Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.
Cardiovasc. Res., 2014 Nov 1 , 104 (337-46).

79

Hansen LK The role of T cell potassium channels, KV1.3 and KCa3.1, in the inflammatory cascade in ulcerative colitis.
Dan Med J, 2014 Nov , 61 (B4946).

80

Koch Hansen L et al. Expression of T-cell KV1.3 potassium channel correlates with pro-inflammatory cytokines and disease activity in ulcerative colitis.
J Crohns Colitis, 2014 Nov , 8 (1378-91).

81

Maleckar MM et al. NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure.
Europace, 2014 Nov , 16 Suppl 4 (iv46-iv55).

82

Abramochkin DV et al. Inhibition of the cardiac ATP-dependent potassium current by KB-R7943.
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol., 2014 May 17 , 175C (38-45).

83

Shenton FC et al. Expression of transient receptor potential channels TRPC1 and TRPV4 in venoatrial endocardium of the rat heart.
Neuroscience, 2014 May 16 , 267 (195-204).

84

Ohya S et al. Upregulation of KCa3.1 K(+) channel in mesenteric lymph node CD4(+) T lymphocytes from a mouse model of dextran sodium sulfate-induced inflammatory bowel disease.
Am. J. Physiol. Gastrointest. Liver Physiol., 2014 May 15 , 306 (G873-85).

85

Ye G et al. Effects of Ca2+-activated potassium and inward rectifier potassium channel on the differentiation of endothelial progenitor cells from human peripheral blood.
Mol. Biol. Rep., 2014 May , 41 (3413-23).

86

Climent B et al. Effects of obesity on vascular potassium channels.
Curr Vasc Pharmacol, 2014 May , 12 (438-52).

87

Panyi G et al. Ion channels and anti-cancer immunity.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2014 Mar 19 , 369 (20130106).

88

Colman MA et al. Evolution and pharmacological modulation of the arrhythmogenic wave dynamics in canine pulmonary vein model.
Europace, 2014 Mar , 16 (416-23).

89

Bae H et al. The stimulating effects of nitric oxide on intermediate conductance Ca²⁺-activated K⁺ channels in human dermal fibroblasts through PKG pathways but not the PKA pathways.
Chin J Physiol, 2014 Jun 30 , 57 (137-51).

90

Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

91

Turner KL et al. A proinvasive role for the Ca(2+) -activated K(+) channel KCa3.1 in malignant glioma.
Glia, 2014 Jun , 62 (971-81).

92

Li HX et al. GATA-4 induces changes in electrophysiological properties of rat mesenchymal stem cells.
Biochim. Biophys. Acta, 2014 Jun , 1840 (2060-9).

93

Catalán MA et al. Ca(2+)-dependent K(+) channels in exocrine salivary glands.
Cell Calcium, 2014 Jun , 55 (362-8).

94

Wang LJ et al. [Relation of intermediate-conductance Ca(2+)-activated K(+) channels with ability of proliferation, migration, invasion and IgE secretion of multiple myeloma cells].
Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2014 Jun , 22 (742-6).

95

Yu Z et al. Targeted inhibition of KCa3.1 attenuates TGF-β-induced reactive astrogliosis through the Smad2/3 signaling pathway.
J. Neurochem., 2014 Jul , 130 (41-9).

96

Kucherenko YV et al. Niflumic Acid Affects Store-Operated Ca(2+)-Permeable (SOC) and Ca (2+)-Dependent K (+) and Cl (-) Ion Channels and Induces Apoptosis in K562 Cells.
J. Membr. Biol., 2014 Jul , 247 (627-38).

97

Freise C et al. Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34.
Pharmacol. Res., 2014 Jul , 85 (6-14).

98

Orban C et al. Different calcium influx characteristics upon Kv1.3 and IKCa1 potassium channel inhibition in T helper subsets.
Cytometry A, 2014 Jul , 85 (636-41).

99

Zhang Q et al. [Effects of telmisartan on IKCa1 potassium channel after T-lymphocyte activation and proliferation in peripheral blood of hypertensive patients in Xinjiang Kazakh].
Zhonghua Yi Xue Za Zhi, 2014 Jan 21 , 94 (182-6).

100

Liu Y et al. Protective effect of piperine on electrophysiology abnormalities of left atrial myocytes induced by hydrogen peroxide in rabbits.
Life Sci., 2014 Jan 17 , 94 (99-105).

101

Turner RW et al. T-type channels buddy up.
Pflugers Arch., 2014 Jan 11 , ().

102

Qu YH et al. Remodeling of ion channel expression may contribute to electrophysiological consequences caused by methamphetamine in vitro and in vivo.
Biochem. Biophys. Res. Commun., 2014 Jan 10 , 443 (441-6).

103

Choi S et al. Globotriaosylceramide induces lysosomal degradation of endothelial KCa3.1 in fabry disease.
Arterioscler. Thromb. Vasc. Biol., 2014 Jan , 34 (81-9).

104

Qian X et al. Positive feedback regulation of agonist-stimulated endothelial Ca2+ dynamics by KCa3.1 channels in mouse mesenteric arteries.
Arterioscler. Thromb. Vasc. Biol., 2014 Jan , 34 (127-35).

105

Sun HY et al. Ionic mechanism underlying distinctive excitability in atrium and ventricle of the heart.
Sheng Li Xue Bao, 2014 Feb 25 , 66 (85-95).

106

Zhang J et al. Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes.
Physiol Rep, 2014 Feb 1 , 2 (e00237).

107

Huang C et al. KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis.
Nephrol. Dial. Transplant., 2014 Feb , 29 (313-24).

108

Huang C et al. Inhibition of KCa3.1 suppresses TGF-β1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways.
Int. J. Biochem. Cell Biol., 2014 Feb , 47 (1-10).

109

Zhao LM et al. Advanced glycation end products impair K(Ca)3.1- and K(Ca)2.3-mediated vasodilatation via oxidative stress in rat mesenteric arteries.
Pflugers Arch., 2014 Feb , 466 (307-17).

110

Wang Y et al. [Ca(2+)-activated K(+) channel switching in smooth muscle participates in atherosclerosis development in diabetic rats].
Nan Fang Yi Ke Da Xue Xue Bao, 2014 Feb , 34 (188-92).

111

Garneau L et al. Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process.
J. Gen. Physiol., 2014 Feb , 143 (289-307).

112

Shao Z et al. Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells.
Transl Res, 2014 Dec 20 , ().

113

Lin H et al. Ca2+ -activated K+ channel-3.1 blocker TRAM-34 alleviates murine allergic rhinitis.
Int. Immunopharmacol., 2014 Dec , 23 (642-8).

114

Xynogalos P et al. Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.
Naunyn Schmiedebergs Arch. Pharmacol., 2014 Dec , 387 (1153-61).

115

Kang H et al. Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease.
Cell Rep, 2014 Aug 21 , 8 (1210-24).

116

Wang Y et al. [Electrophysiological study on the antiarrhythmic mechanism of ampelopsin in rats].
Zhonghua Xin Xue Guan Bing Za Zhi, 2014 Aug , 42 (675-9).

117

Bébarová M et al. Dual effect of ethanol on inward rectifier potassium current IK1 in rat ventricular myocytes.
J. Physiol. Pharmacol., 2014 Aug , 65 (497-509).

118

Grössinger EM et al. Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
Leukemia, 2014 Apr , 28 (954-8).

119

Wandall-Frostholm C et al. Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 channels.
PLoS ONE, 2014 , 9 (e97687).

120

Roach KM et al. Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.
Respir. Res., 2014 , 15 (155).

121

Gu J et al. Pioglitazone improves potassium channel remodeling induced by angiotensin II in atrial myocytes.
Med Sci Monit Basic Res, 2014 , 20 (153-60).

122

Yu CC et al. Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents.
PLoS ONE, 2014 , 9 (e96691).

123

Ferreira R et al. IL-4 type 1 receptor signaling up-regulates KCNN4 expression, and increases the KCa3.1 current and its contribution to migration of alternative-activated microglia.
Front Cell Neurosci, 2014 , 8 (183).

124

Folyovich A et al. Kv1.3 lymphocyte potassium channel inhibition as a potential novel therapeutic target in acute ischemic stroke.
CNS Neurol Disord Drug Targets, 2014 , 13 (801-6).

125

Odagiri F et al. Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.
PLoS ONE, 2014 , 9 (e101838).

126

Xu H et al. Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner.
BMC Cancer, 2014 , 14 (330).

127

Bertuccio CA et al. Anterograde trafficking of KCa3.1 in polarized epithelia is Rab1- and Rab8-dependent and recycling endosome-independent.
PLoS ONE, 2014 , 9 (e92013).

128

Tong WC et al. Computational modeling reveals key contributions of KCNQ and hERG currents to the malleability of uterine action potentials underpinning labor.
PLoS ONE, 2014 , 9 (e114034).

129

Gole HK et al. Upregulation of intermediate-conductance Ca2+-activated K+ channels (KCNN4) in porcine coronary smooth muscle requires NADPH oxidase 5 (NOX5).
PLoS ONE, 2014 , 9 (e105337).

130

Climent B et al. Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats.
PLoS ONE, 2014 , 9 (e109432).

131

Simma N et al. NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.
Cell Commun. Signal, 2014 , 12 (75).

132

O'Hara B et al. Multiple mineralocorticoid response elements localized in different introns regulate intermediate conductance K+ (Kcnn4) channel expression in the rat distal colon.
PLoS ONE, 2014 , 9 (e98695).

133

Huang C et al. High glucose induces CCL20 in proximal tubular cells via activation of the KCa3.1 channel.
PLoS ONE, 2014 , 9 (e95173).

134

Yap FC et al. Ovariectomy-induced reductions in endothelial SK3 channel activity and endothelium-dependent vasorelaxation in murine mesenteric arteries.
PLoS ONE, 2014 , 9 (e104686).

135

Jenkins DP et al. Development of a QPatch automated electrophysiology assay for identifying KCa3.1 inhibitors and activators.
Assay Drug Dev Technol, 2013 Nov-Dec , 11 (551-60).

136

Colman MA et al. Pro-arrhythmogenic effects of atrial fibrillation-induced electrical remodelling: insights from the three-dimensional virtual human atria.
J. Physiol. (Lond.), 2013 Sep 1 , 591 (4249-72).

137

van der Heyden MA et al. Inhibition of cardiac inward rectifier currents by cationic amphiphilic drugs.
Curr. Mol. Med., 2013 Sep , 13 (1284-98).

138

Radtke J et al. Activation of KCa3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice.
Br. J. Pharmacol., 2013 Sep , 170 (293-303).

139

Zhang L et al. Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes.
Sci China Life Sci, 2013 Sep , 56 (788-96).

140

Abramochkin DV et al. Inhibition of the cardiac inward rectifier potassium currents by KB-R7943.
Comp. Biochem. Physiol. C Toxicol. Pharmacol., 2013 Sep , 158 (181-6).

141

Chen R et al. Molecular dynamics simulations of scorpion toxin recognition by the Ca(2+)-activated potassium channel KCa3.1.
Biophys. J., 2013 Oct 15 , 105 (1829-37).

142

Chinnathambi V et al. Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats.
Biol. Reprod., 2013 Oct , 89 (97).

143

Song YJ et al. Regulatory functions of docosahexaenoic acid on ion channels in rat ventricular myocytes.
Eur Rev Med Pharmacol Sci, 2013 Oct , 17 (2632-8).

144

Stoneking CJ et al. Mg(2+) modulation of the single-channel properties of KCa3.1 in human erythroleukemia cells.
Pflugers Arch., 2013 Nov 6 , ().

145

Nagy N et al. [Ca²⁺] i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium.
Pflugers Arch., 2013 Nov , 465 (1621-35).

146

Horváth B et al. Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.
J. Mol. Cell. Cardiol., 2013 Nov , 64 (59-68).

147

Yu ZH et al. Up-regulation of KCa3.1 promotes human airway smooth muscle cell phenotypic modulation.
Pharmacol. Res., 2013 Nov , 77 (30-8).

148

Soltan Mohammadi N et al. Identification and characterization of the channel-forming protein in the cell wall of Corynebacterium amycolatum.
Biochim. Biophys. Acta, 2013 Nov , 1828 (2574-82).

149

Fagerberg SK et al. P2X receptor-dependent erythrocyte damage by α-hemolysin from Escherichia coli triggers phagocytosis by THP-1 cells.
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