Channelpedia

Nav1.5

1259 literature references associated to Nav1.5

used / unused
Pubmed id

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365259

Schilling JM et al. Electrophysiology and metabolism of caveolin-3-overexpressing mice.
Basic Res. Cardiol., 2016 May , 111 (28).

9

365520

Zaklyazminskaya E et al. The role of mutations in the SCN5A gene in cardiomyopathies.
Biochim. Biophys. Acta, 2016 Jul , 1863 (1799-805).

10

365540

Sottas V et al. Negative-dominance phenomenon with genetic variants of the cardiac sodium channel Nav1.5.
Biochim. Biophys. Acta, 2016 Jul , 1863 (1791-8).

12

361465

Wang HG et al. A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.
J. Mol. Cell. Cardiol., 2016 Jan 19 , 92 (52-62).

13

361658

18

365608

20

365061

Kubanek J et al. Ultrasound modulates ion channel currents.
Sci Rep, 2016 , 6 (24170).

23

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26

356252

Climent AM et al. The Role of Atrial Tissue Remodeling on Rotor Dynamics: An In-Vitro Study.
Am. J. Physiol. Heart Circ. Physiol., 2015 Sep 25 , (ajpheart.00055.2015).

27

368205

Abdelsayed M et al. Differential thermosensitivity in mixed syndrome cardiac sodium channel mutants.
J. Physiol. (Lond.), 2015 Sep 15 , 593 (4201-23).

28

362596

Neshatian L et al. Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Sep 15 , 309 (G506-12).

29

366312

30

366344

Aktas CC et al. In vitro effects of phenytoin and DAPT on MDA-MB-231 breast cancer cells.
Acta Biochim. Biophys. Sin. (Shanghai), 2015 Sep , 47 (680-6).

32

356295

Musa H et al. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Proc. Natl. Acad. Sci. U.S.A., 2015 Oct 6 , 112 (12528-33).

35

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36

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37

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38

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39

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Han Z et al. The effects of A-803467 on cardiac Nav1.5 channels.
Eur. J. Pharmacol., 2015 May 5 , 754 (52-60).

42

363297

Marionneau C et al. Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications.
J. Mol. Cell. Cardiol., 2015 May , 82 (36-47).

44

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48

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Ossola D et al. Force-controlled patch clamp of beating cardiac cells.
Nano Lett., 2015 Mar 11 , 15 (1743-50).

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51

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54

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Stroemlund LW et al. Gap junctions - guards of excitability.
Biochem. Soc. Trans., 2015 Jun , 43 (508-12).

60

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Wannous R et al. Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.
Pflugers Arch., 2015 Jun , 467 (1249-59).

61

358071

Mercier A et al. Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states.
Biochim. Biophys. Acta, 2015 Jun , 1850 (1215-23).

62

356691

Stattin EL et al. Genetic screening in sudden cardiac death in the young can save future lives.
Int. J. Legal Med., 2015 Jul 31 , ().

63

356703

Watanabe H et al. Genetics of Brugada syndrome.
J. Hum. Genet., 2015 Jul 30 , ().

65

367232

Verstraelen TE et al. The role of the SCN5A-encoded channelopathy in irritable bowel syndrome and other gastrointestinal disorders.
Neurogastroenterol. Motil., 2015 Jul , 27 (906-13).

70

348893

Saber S et al. Complex genetic background in a large family with Brugada syndrome.
Physiol Rep, 2015 Jan 1 , 3 ().

72

349473

Baruteau AE et al. Inherited progressive cardiac conduction disorders.
Curr. Opin. Cardiol., 2015 Jan , 30 (33-9).

73

358682

Wilde AA et al. Bringing home the bacon? The next step in cardiac sodium channelopathies.
J. Clin. Invest., 2015 Jan , 125 (99-101).

74

358681

Park DS et al. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.
J. Clin. Invest., 2015 Jan , 125 (403-12).

76

360806

Riuró H et al. Genetic analysis, in silico prediction, and family segregation in long QT syndrome.
Eur. J. Hum. Genet., 2015 Jan , 23 (79-85).

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79

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82

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83

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84

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Peters CH et al. Triggers for arrhythmogenesis in the Brugada and long QT 3 syndromes.
Prog. Biophys. Mol. Biol., 2015 Dec 20 , ().

86

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Qureshi SF et al. Mutational analysis of SCN5A gene in long QT syndrome.
Meta Gene, 2015 Dec , 6 (26-35).

88

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90

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Potet F et al. Intracellular calcium attenuates late current conducted by mutant human cardiac sodium channels.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (933-41).

94

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Willis BC et al. Protein Assemblies of Sodium and Inward Rectifier Potassium Channels Control Cardiac Excitability and Arrhythmogenesis.
Am. J. Physiol. Heart Circ. Physiol., 2015 Apr 10 , (ajpheart.00176.2015).

102

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103

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Han Z et al. Deletion of PDK1 causes cardiac sodium current reduction in mice.
PLoS ONE, 2015 , 10 (e0122436).

105

366203

Wang L et al. De Novo Mutation in the SCN5A Gene Associated with Brugada Syndrome.
Cell. Physiol. Biochem., 2015 , 36 (2250-62).

107

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112

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113

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Mirams GR et al. Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
J Pharmacol Toxicol Methods, 2014 Nov-Dec , 70 (246-54).

114

351334

Brugada R et al. Brugada syndrome.
Methodist Debakey Cardiovasc J, 2014 Jan-Mar , 10 (25-8).

115

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Sayeed MZ et al. Brugada syndrome with a novel missense mutation in SCN5A gene: a case report from Bangladesh.
Indian Heart J, 2014 Jan-Feb , 66 (104-7).

117

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118

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Ho GD et al. Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers.
Bioorg. Med. Chem. Lett., 2014 Sep 1 , 24 (4110-3).

119

360498

121

344657

Bartok A et al. Margatoxin is a non-selective inhibitor of human Kv1.3 K(+) channels.
Toxicon, 2014 Sep , 87 (6-16).

122

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van Hoeijen DA et al. Cardiac sodium channels and inherited electrophysiological disorders: an update on the pharmacotherapy.
Expert Opin Pharmacother, 2014 Sep , 15 (1875-87).

123

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125

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Shi D et al. Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias.
J. Cell. Mol. Med., 2014 Oct , 18 (1992-9).

126

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127

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Liu M et al. Cardiac sodium channel mutations: why so many phenotypes?
Nat Rev Cardiol, 2014 Oct , 11 (607-15).

128

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Wang X et al. Angiotensin-(1-7) prevent atrial tachycardia induced sodium channel remodeling.
Pacing Clin Electrophysiol, 2014 Oct , 37 (1349-56).

130

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131

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132

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133

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Chatin B et al. Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5.
Biochem. J., 2014 Nov 1 , 463 (339-49).

137

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Ilkhanoff L et al. A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans.
J. Cardiovasc. Electrophysiol., 2014 Nov , 25 (1150-7).

139

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Frolov RV et al. Celecoxib and ion channels: a story of unexpected discoveries.
Eur. J. Pharmacol., 2014 May 5 , 730 (61-71).

143

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144

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Wang Q et al. Gain-of-function KCNH2 mutations in patients with Brugada syndrome.
J. Cardiovasc. Electrophysiol., 2014 May , 25 (522-30).

147

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Andreasen L et al. Brugada syndrome risk loci seem protective against atrial fibrillation.
Eur. J. Hum. Genet., 2014 Mar 26 , ().

149

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152

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Elíes J et al. Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide.
J. Biol. Chem., 2014 Jun 6 , 289 (16421-9).

156

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Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

157

344483

Ben-Johny M et al. Conservation of Ca(2+)/Calmodulin Regulation across Na and Ca(2+) Channels.
Cell, 2014 Jun 19 , 157 (1657-70).

158

345110

Zhang Y et al. Measurement and interpretation of electrocardiographic QT intervals in murine hearts.
Am. J. Physiol. Heart Circ. Physiol., 2014 Jun 1 , 306 (H1553-7).

160

351993

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

162

352022

Alday A et al. Ionic channels underlying the ventricular action potential in zebrafish embryo.
Pharmacol. Res., 2014 Jun , 84 (26-31).

165

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169

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Hu D et al. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.
J. Am. Coll. Cardiol., 2014 Jul 8 , 64 (66-79).

170

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Dybkova N et al. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa.
Cardiovasc. Res., 2014 Jul 1 , 103 (168-77).

173

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Glengarry JM et al. Long QT molecular autopsy in sudden infant death syndrome.
Arch. Dis. Child., 2014 Jul , 99 (635-40).

174

351205

Friedrich C et al. Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.
EMBO Mol Med, 2014 Jul , 6 (937-51).

180

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Gajewiak J et al. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.
Proc. Natl. Acad. Sci. U.S.A., 2014 Feb 18 , 111 (2758-63).

181

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Hu D et al. ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.
Int. J. Cardiol., 2014 Feb 15 , 171 (431-42).

182

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185

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Jones JM et al. Modeling human epilepsy by TALEN targeting of mouse sodium channel Scn8a.
Genesis, 2014 Feb , 52 (141-8).

186

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Zhang Y et al. The SCN5A mutation A1180V is associated with electrocardiographic features of LQT3.
Pediatr Cardiol, 2014 Feb , 35 (295-300).

187

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189

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Schroder EA et al. Light phase-restricted feeding slows basal heart rate to exaggerate the type-3 long QT syndrome phenotype in mice.
Am. J. Physiol. Heart Circ. Physiol., 2014 Dec 15 , 307 (H1777-85).

190

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191

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Savio-Galimberti E et al. Atrial Fibrillation and SCN5A Variants.
Card Electrophysiol Clin, 2014 Dec 1 , 6 (741-748).

192

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193

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Lodder EM et al. Integrative genomic approach identifies multiple genes involved in cardiac collagen deposition.
Circ Cardiovasc Genet, 2014 Dec , 7 (790-8).

194

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Huang WF et al. Role of sodium channels in the spontaneous excitability of early embryonic cardiomyocytes.
Chin J Physiol, 2014 Aug 31 , 57 (188-97).

195

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202

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Amin AS SCN5A-related dilated cardiomyopathy: what do we know?
Heart Rhythm, 2014 Aug , 11 (1454-5).

203

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206

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207

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Hoshi M et al. Brugada syndrome disease phenotype explained in apparently benign sodium channel mutations.
Circ Cardiovasc Genet, 2014 Apr 1 , 7 (123-31).

208

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Park DS et al. Nav-igating through a complex landscape: SCN10A and cardiac conduction.
J. Clin. Invest., 2014 Apr 1 , 124 (1460-2).

209

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Abriel H et al. Unexpected α-α interactions with NaV1.5 genetic variants in Brugada syndrome.
Circ Cardiovasc Genet, 2014 Apr 1 , 7 (97-9).

210

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van den Boogaard M et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression.
J. Clin. Invest., 2014 Apr 1 , 124 (1844-52).

211

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Wang D et al. Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths.
Forensic Sci. Int., 2014 Apr , 237 (90-9).

212

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Kruse M et al. TRPM4 channels in the cardiovascular system.
Curr Opin Pharmacol, 2014 Apr , 15 (68-73).

213

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214

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Tester DJ et al. GENETICS OF LONG QT SYNDROME.
Methodist Debakey Cardiovasc J, 2014 1 , 10 (29-33).

215

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219

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Moreau A et al. Biophysics, pathophysiology, and pharmacology of ion channel gating pores.
Front Pharmacol, 2014 , 5 (53).

223

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Antzelevitch C et al. The role of late I Na in development of cardiac arrhythmias.
Handb Exp Pharmacol, 2014 , 221 (137-68).

224

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Jones DK et al. Proton modulation of cardiac I Na: a potential arrhythmogenic trigger.
Handb Exp Pharmacol, 2014 , 221 (169-81).

227

351338

Miller D et al. Sodium channels, cardiac arrhythmia, and therapeutic strategy.
Adv. Pharmacol., 2014 , 70 (367-92).

229

353546

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

230

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Zakliaz'minskaia EV et al. [Dilated cardiomyopathy caused by p.E446K mutation in SCN5A gene].
Kardiologiia, 2014 , 54 (92-6).

233

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Shimizu W Clinical and genetic diagnosis for inherited cardiac arrhythmias.
J Nippon Med Sch, 2014 , 81 (203-10).

235

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237

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Ertugrul I et al. Follow up of a family with asymptomatic compound long QT syndrome mutations.
Genet. Couns., 2014 , 25 (399-403).

241

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242

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Sumitomo N E1784K mutation in SCN5A and overlap syndrome.
Circ. J., 2014 , 78 (1839-40).

244

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245

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Gabelli SB et al. Regulation of the NaV1.5 cytoplasmic domain by calmodulin.
Nat Commun, 2014 , 5 (5126).

246

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248

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Barajas-Martinez H et al. [Genetic and molecular basis for sodium channel-mediated Brugada syndrome].
Arch Cardiol Mex, 2013 Oct-Dec , 83 (295-302).

249

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Partemi S et al. Analysis of the arrhythmogenic substrate in human heart failure.
Cardiovasc. Pathol., 2013 Mar-Apr , 22 (133-40).

250

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Hermida JS et al. Dual phenotypic transmission in Brugada syndrome.
Arch Cardiovasc Dis, 2013 Jun-Jul , 106 (366-72).

251

335392

Morissette P et al. The anesthetized guinea pig: An effective early cardiovascular derisking and lead optimization model.
J Pharmacol Toxicol Methods, 2013 Jul-Aug , 68 (137-49).

252

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Elkins RC et al. Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment.
J Pharmacol Toxicol Methods, 2013 Jul-Aug , 68 (112-22).

255

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Lang F et al. Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth.
Hormones (Athens), 2013 Apr-Jun , 12 (160-71).

257

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258

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Shryock JC et al. The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.
Cardiovasc. Res., 2013 Sep 1 , 99 (600-11).

262

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Matthews GD et al. Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/-) hearts.
J. Physiol. (Lond.), 2013 Sep 1 , 591 (4167-88).

266

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267

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268

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Sottas V et al. Characterization of 2 genetic variants of Na(v) 1.5-arginine 689 found in patients with cardiac arrhythmias.
J. Cardiovasc. Electrophysiol., 2013 Sep , 24 (1037-46).

271

342061

Black JA et al. Noncanonical roles of voltage-gated sodium channels.
Neuron, 2013 Oct 16 , 80 (280-91).

272

342482

Sheets MF et al. Outward stabilization of the voltage sensor in domain II but not domain I speeds inactivation of voltage-gated sodium channels.
Am. J. Physiol. Heart Circ. Physiol., 2013 Oct 15 , 305 (H1213-21).

274

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276

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278

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279

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Lee YS et al. Long QT syndrome: a Korean single center study.
J. Korean Med. Sci., 2013 Oct , 28 (1454-60).

280

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Gao G et al. Unfolded protein response regulates cardiac sodium current in systolic human heart failure.
Circ Arrhythm Electrophysiol, 2013 Oct , 6 (1018-24).

281

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Hummel YM et al. Ventricular dysfunction in a family with long QT syndrome type 3.
Europace, 2013 Oct , 15 (1516-21).

284

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285

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291

347765

Aziz PF et al. Do LQTS gene single nucleotide polymorphisms alter QTc intervals at rest and during exercise stress testing?
Ann Noninvasive Electrocardiol, 2013 May , 18 (288-93).

294

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Kim JJ et al. Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk.
Am. J. Physiol. Heart Circ. Physiol., 2013 Mar 15 , 304 (H848-60).

295

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296

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Letsas KP et al. Sinus node disease in subjects with type 1 ECG pattern of Brugada syndrome.
J Cardiol, 2013 Mar , 61 (227-31).

299

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Panguluri SK et al. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle.
Am. J. Physiol. Heart Circ. Physiol., 2013 Jun , 304 (H1651-61).

300

335911

Lang F et al. Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.
Expert Opin Investig Drugs, 2013 Jun , 22 (701-14).

302

343978

García-Molina E et al. A study of the SCN5A gene in a cohort of 76 patients with Brugada syndrome.
Clin. Genet., 2013 Jun , 83 (530-8).

304

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Nilsson MF et al. Comparative effects of sodium channel blockers in short term rat whole embryo culture.
Toxicol. Appl. Pharmacol., 2013 Jul 8 , ().

307

344236

308

340030

McCormack K et al. Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jul 16 , 110 (E2724-32).

309

335174

Ravens U et al. Atrial selectivity of antiarrhythmic drugs.
J. Physiol. (Lond.), 2013 Jul 16 , ().

310

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Takanari H et al. Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue.
Cardiovasc. Res., 2013 Jul 1 , 99 (203-14).

311

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Gillet L et al. NaV1.5 and interacting proteins in human arrhythmogenic cardiomyopathy.
Future Cardiol, 2013 Jul , 9 (467-70).

313

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314

347938

315

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316

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Zhang Q et al. [Desmoplakin expression silencing affects cardiac voltage-gated sodium channel Nav1.5 in HL-1 cells].
Nan Fang Yi Ke Da Xue Xue Bao, 2013 Jul , 33 (983-9).

317

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Schroder EA et al. The Cardiomyocyte Molecular Clock, Regulation of Scn5a and Arrhythmia Susceptibility.
Am. J. Physiol., Cell Physiol., 2013 Jan 30 , ().

319

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321

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322

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323

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Gao G et al. RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.
Trends Cardiovasc. Med., 2013 Jan , 23 (5-8).

326

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328

340626

Gao G et al. SCN5A splicing variants and the possibility of predicting heart failure-associated arrhythmia.
Expert Rev Cardiovasc Ther, 2013 Feb , 11 (117-9).

330

341526

van den Boogaard M et al. From GWAS to function: Genetic variation in sodium channel gene enhancer influences electrical patterning.
Trends Cardiovasc. Med., 2013 Dec 17 , ().

331

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Yu JH et al. [SCN5A mutation in patients with Brugada electrocardiographic pattern induced by fever].
Zhonghua Xin Xue Guan Bing Za Zhi, 2013 Dec , 41 (1010-4).

333

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Wahbi K et al. Brugada syndrome and abnormal splicing of SCN5A in myotonic dystrophy type 1.
Arch Cardiovasc Dis, 2013 Dec , 106 (635-43).

334

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335

339752

van Duijvenboden K et al. Gene regulatory elements of the cardiac conduction system.
Brief Funct Genomics, 2013 Aug 22 , ().

336

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Bradley E et al. The cardiac sodium current Na(v)1.5 is functionally expressed in rabbit bronchial smooth muscle cells.
Am. J. Physiol., Cell Physiol., 2013 Aug 15 , 305 (C427-35).

337

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338

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Li X et al. [A simulation study for the effect of acid concentration and temperture on sick sinus syndrome].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2013 Aug , 30 (697-703).

339

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340

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Parisi P et al. Coexistence of epilepsy and Brugada syndrome in a family with SCN5A mutation.
Epilepsy Res., 2013 Aug , 105 (415-8).

343

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Cheng J et al. Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (102-10).

344

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345

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Rhett JM et al. The perinexus: sign-post on the path to a new model of cardiac conduction?
Trends Cardiovasc. Med., 2013 Aug , 23 (222-8).

346

347211

Li A et al. Genetic biomarkers in Brugada syndrome.
Biomark Med, 2013 Aug , 7 (535-46).

348

347800

Kaufmann SG et al. Distribution and function of sodium channel subtypes in human atrial myocardium.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (133-41).

350

335640

Crotti L et al. Long QT syndrome-associated mutations in intrauterine fetal death.
JAMA, 2013 Apr 10 , 309 (1473-82).

351

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Hu RM et al. Digenic inheritance novel mutations in SCN5a and SNTA1 increase late I(Na) contributing to LQT syndrome.
Am. J. Physiol. Heart Circ. Physiol., 2013 Apr 1 , 304 (H994-H1001).

352

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354

343989

Black JA et al. Nav1.5 sodium channels in macrophages in multiple sclerosis lesions.
Mult. Scler., 2013 Apr , 19 (532-42).

359

339952

Reingardienė D et al. Brugada-like electrocardiographic patterns induced by hyperkalemia.
Medicina (Kaunas), 2013 , 49 (148-53).

360

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Auerbach DS et al. Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.
PLoS ONE, 2013 , 8 (e77843).

364

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369

341891

371

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372

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Hegyi B et al. Selectivity problems with drugs acting on cardiac Na⁺ and Ca²⁺ channels.
Curr. Med. Chem., 2013 , 20 (2552-71).

373

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374

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376

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Di Domenico M et al. Biomarker discovery by plasma proteomics in familial Brugada Syndrome.
Front. Biosci., 2013 , 18 (564-71).

379

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380

347110

386

341161

390

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391

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Zumhagen S et al. Inherited long QT syndrome: clinical manifestation, genetic diagnostics, and therapy.
Herzschrittmacherther Elektrophysiol, 2012 Sep , 23 (211-9).

392

331340

Balasuriya D et al. The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
J. Biol. Chem., 2012 Oct 26 , 287 (37021-9).

393

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Mann SA et al. R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy.
J. Am. Coll. Cardiol., 2012 Oct 16 , 60 (1566-73).

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396

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397

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398

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399

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401

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Hong K et al. Concomitant Brugada-like and short QT electrocardiogram linked to SCN5A mutation.
Eur. J. Hum. Genet., 2012 Nov , 20 (1189-92).

403

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408

333246

Santos LF et al. [Diagnostic criteria for the Brugada syndrome: can they be improved?].
Rev Port Cardiol, 2012 May , 31 (355-62).

413

329133

Besana A et al. Nadolol block of Nav1.5 does not explain its efficacy in the long QT syndrome.
J. Cardiovasc. Pharmacol., 2012 Mar , 59 (249-53).

417

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Hardziyenka M et al. Electrophysiologic remodeling of the left ventricle in pressure overload-induced right ventricular failure.
J. Am. Coll. Cardiol., 2012 Jun 12 , 59 (2193-202).

418

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Catalano A et al. An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite.
Drug Metab Lett, 2012 Jun 1 , 6 (124-8).

419

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425

328011

Gönczi M et al. Age-dependent changes in ion channel mRNA expression in canine cardiac tissues.
Gen. Physiol. Biophys., 2012 Jun , 31 (153-62).

426

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Ren CT et al. Cloning and expression of the two new variants of Nav1.5/SCN5A in rat brain.
Mol. Cell. Biochem., 2012 Jun , 365 (139-48).

429

328117

Yang T et al. Blocking scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Circ. Res., 2012 Jul 20 , 111 (322-32).

430

328148

van den Boogaard M et al. Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
J. Clin. Invest., 2012 Jul 2 , 122 (2519-30).

431

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Arnolds DE et al. TBX5 drives Scn5a expression to regulate cardiac conduction system function.
J. Clin. Invest., 2012 Jul 2 , 122 (2509-18).

433

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Laurent G et al. Multifocal Ectopic Purkinje-Related Premature Contractions: A New SCN5A-Related Cardiac Channelopathy.
J. Am. Coll. Cardiol., 2012 Jul 10 , 60 (144-56).

439

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Lu J et al. Improving cardiac conduction with a skeletal muscle sodium channel by gene and cell therapy.
J. Cardiovasc. Pharmacol., 2012 Jul , 60 (88-99).

441

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Poh YC et al. Quantification of gastrointestinal sodium channelopathy.
J. Theor. Biol., 2012 Jan 21 , 293 (41-8).

442

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