Nav1.8

1

Rosberg MR et al. Progression of motor axon dysfunction and ectopic Nav1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B.
Neurobiol. Dis., 2016 May 20 , 93 (201-214).

2

Han C et al. Sodium channel Nav1.8: Emerging links to human disease.
Neurology, 2016 Feb 2 , 86 (473-83).

3

Roostaei T et al. Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis.
Neurology, 2016 Feb 2 , 86 (410-7).

4

Ye P et al. Functional up-regulation of Nav1.8 sodium channel on dorsal root ganglia neurons contributes to the induction of scorpion sting pain.
Acta Biochim. Biophys. Sin. (Shanghai), 2016 Feb , 48 (132-44).

5

Rannals MD et al. Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.
Neuron, 2016 Apr 6 , 90 (43-55).

6

Zhao Y et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord, 2016 , 16 (1).

7

Wang X et al. Characterization of Specific Roles of Sodium Channel Subtypes in Regional Anesthesia.
Reg Anesth Pain Med, 2015 Sep-Oct , 40 (599-604).

8

Coll M et al. Genetic investigation of sudden unexpected death in epilepsy cohort by panel target resequencing.
Int. J. Legal Med., 2015 Sep 30 , ().

9

Remacle AG et al. Matrix Metalloproteinase (MMP) Proteolysis of the Extracellular Loop of Voltage-gated Sodium Channels and Potential Alterations in Pain Signaling.
J. Biol. Chem., 2015 Sep 18 , 290 (22939-44).

10

Li G et al. Positive shift of Nav1.8 current inactivation curve in injured neurons causes neuropathic pain following chronic constriction injury.
Mol Med Rep, 2015 Sep , 12 (3583-90).

11

Namer B et al. Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7.
Pain, 2015 Sep , 156 (1637-46).

12

Estacion M et al. Ca2+ toxicity due to reverse Na+/Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation.
J. Neurophysiol., 2015 Sep , 114 (1554-64).

13

Patel R et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci., 2015 Oct 10 , ().

14

Zheng G et al. Chronic stress and peripheral pain: Evidence for distinct, region-specific changes in visceral and somatosensory pain regulatory pathways.
Exp. Neurol., 2015 Nov , 273 (301-11).

15

Han Z et al. The effects of A-803467 on cardiac Nav1.5 channels.
Eur. J. Pharmacol., 2015 May 5 , 754 (52-60).

16

Lu VB et al. A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal.
J. Neurosci., 2015 May 20 , 35 (8021-34).

17

Le Scouarnec S et al. Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome.
Hum. Mol. Genet., 2015 May 15 , 24 (2757-63).

18

Han C et al. Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons.
J. Neurophysiol., 2015 Mar 18 , (jn.00113.2015).

19

Tigerholm J et al. C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability.
Biophys. J., 2015 Mar 10 , 108 (1057-71).

20

Rahman W et al. Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat.
Neuroscience, 2015 Jun 4 , 295 (103-16).

21

Behr ER et al. Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.
Cardiovasc. Res., 2015 Jun 1 , 106 (520-9).

22

Ye P et al. Scorpion toxin BmK I directly activates Nav1.8 in primary sensory neurons to induce neuronal hyperexcitability in rats.
Protein Cell, 2015 Jun , 6 (443-52).

23

Han C et al. The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy.
Neuromolecular Med., 2015 Jun , 17 (158-69).

24

Talbot S et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Neuron, 2015 Jul 15 , 87 (341-54).

25

Pucca MB et al. Revealing the Function and the Structural Model of Ts4: Insights into the "Non-Toxic" Toxin from Tityus serrulatus Venom.
Toxins (Basel), 2015 Jul , 7 (2534-50).

26

Hasdemir C et al. High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia.
Heart Rhythm, 2015 Jul , 12 (1584-94).

27

Baruteau AE et al. Inherited progressive cardiac conduction disorders.
Curr. Opin. Cardiol., 2015 Jan , 30 (33-9).

28

Stoetzer C et al. Methadone is a local anaesthetic-like inhibitor of neuronal Na+ channels and blocks excitability of mouse peripheral nerves.
Br J Anaesth, 2015 Jan , 114 (110-20).

29

Zhang F et al. Natural mutations change the affinity of μ-theraphotoxin-Hhn2a to voltage-gated sodium channels.
Toxicon, 2015 Jan , 93 (24-30).

30

Feng B et al. Experimental and computational evidence for an essential role of NaV1.6 in spike initiation at stretch-sensitive colorectal afferent endings.
J. Neurophysiol., 2015 Feb 4 , (jn.00717.2014).

31

Jabbari J et al. Common and rare variants in SCN10A modulate the risk of atrial fibrillation.
Circ Cardiovasc Genet, 2015 Feb , 8 (64-73).

32

Habib AM et al. Sodium channels and pain.
Handb Exp Pharmacol, 2015 , 227 (39-56).

33

Iio C et al. Association Between Genetic Variation in the SCN10A Gene and Cardiac Conduction Abnormalities in Patients With Hypertrophic Cardiomyopathy.
Int Heart J, 2015 , 56 (421-7).

34

Gu XY et al. Dexmedetomidine inhibits Tetrodotoxin-resistant Nav1.8 sodium channel activity through Gi/o-dependent pathway in rat dorsal root ganglion neurons.
Mol Brain, 2015 , 8 (15).

35

Shields SD et al. Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis.
PLoS ONE, 2015 , 10 (e0119067).

36

Bao L Trafficking regulates the subcellular distribution of voltage-gated sodium channels in primary sensory neurons.
Mol Pain, 2015 , 11 (61).

37

Kharatmal SB et al. Voltage-Gated Sodium Channels as Therapeutic Targets for Treatment of Painful Diabetic Neuropathy.
Mini Rev Med Chem, 2015 , 15 (1134-47).

38

Poulet C et al. Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation.
PLoS ONE, 2015 , 10 (e0131432).

39

Doran C et al. Mouse DRG Cell Line with Properties of Nociceptors.
PLoS ONE, 2015 , 10 (e0128670).

40

Ding T et al. Neural tissue engineering scaffold with sustained RAPA release relieves neuropathic pain in rats.
Life Sci., 2014 Sep 1 , 112 (22-32).

41

Horishita T et al. Neurosteroids allopregnanolone sulfate and pregnanolone sulfate have diverse effect on the α subunit of the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 expressed in xenopus oocytes.
Anesthesiology, 2014 Sep , 121 (620-31).

42

Hirofuji S et al. Role of sodium channels in recovery of sciatic nerve-stretch injury in rats.
Muscle Nerve, 2014 Sep , 50 (425-30).

43

Yue JX et al. Histamine upregulates Nav1.8 expression in primary afferent neurons via H2 receptors: involvement in neuropathic pain.
CNS Neurosci Ther, 2014 Oct , 20 (883-92).

44

Savio-Galimberti E et al. SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.
Cardiovasc. Res., 2014 Nov 1 , 104 (355-63).

45

Waxman SG et al. Sodium channel genes in pain-related disorders: phenotype-genotype associations and recommendations for clinical use.
Lancet Neurol, 2014 Nov , 13 (1152-60).

46

Kiss T et al. Down regulation of sodium channels in the central nervous system of hibernating snails.
Physiol. Behav., 2014 May 28 , 131 (93-8).

47

Tan ZY et al. Tetrodotoxin-resistant sodium channels in sensory neurons generate slow resurgent currents that are enhanced by inflammatory mediators.
J. Neurosci., 2014 May 21 , 34 (7190-7).

48

Han C et al. The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability.
J. Neurol. Neurosurg. Psychiatr., 2014 May , 85 (499-505).

49

Garrison SR et al. A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons.
Pain, 2014 May , 155 (896-905).

50

Andreasen L et al. Brugada syndrome risk loci seem protective against atrial fibrillation.
Eur. J. Hum. Genet., 2014 Mar 26 , ().

51

Thériault O et al. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
Eur. J. Pharmacol., 2014 Mar 15 , 727 (158-66).

52

Okura D et al. The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes.
Anesth. Analg., 2014 Mar , 118 (554-62).

53

Black JA et al. Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus.
Exp. Neurol., 2014 Mar , 253 (174-9).

54

Riol-Blanco L et al. Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.
Nature, 2014 Jun 5 , 510 (157-61).

55

Chen WN et al. Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia.
Mol Pain, 2014 Jun 23 , 10 (40).

56

Xia L et al. Upregulation of Nav1.8 in Demyelinated Facial Nerves Might be Relevant to the Generation of Hemifacial Spasm.
J Craniofac Surg, 2014 Jun 2 , ().

57

Nutter TJ et al. Persistent modification of Nav1.9 following chronic exposure to insecticides and pyridostigmine bromide.
Toxicol. Appl. Pharmacol., 2014 Jun 15 , 277 (298-309).

58

Qi B et al. Nav1.8 channels in ganglionated plexi modulate atrial fibrillation inducibility.
Cardiovasc. Res., 2014 Jun 1 , 102 (480-6).

59

Bennett DL et al. Painful and painless channelopathies.
Lancet Neurol, 2014 Jun , 13 (587-99).

60

Huang J et al. Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy.
Brain, 2014 Jun , 137 (1627-42).

61

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

62

Liang J et al. Blockade of Nav1.8 currents in nociceptive trigeminal neurons contributes to anti-trigeminovascular nociceptive effect of amitriptyline.
Neuromolecular Med., 2014 Jun , 16 (308-21).

63

Brouwer BA et al. Painful neuropathies: the emerging role of sodium channelopathies.
J. Peripher. Nerv. Syst., 2014 Jun , 19 (53-65).

64

Hu D et al. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.
J. Am. Coll. Cardiol., 2014 Jul 8 , 64 (66-79).

65

Minett MS et al. Pain without nociceptors? Nav1.7-independent pain mechanisms.
Cell Rep, 2014 Jan 30 , 6 (301-12).

66

Isensee J et al. Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons.
J. Cell. Sci., 2014 Jan 1 , 127 (216-29).

67

Muroi Y et al. Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough.
Lung, 2014 Feb , 192 (15-20).

68

Cheng KI et al. Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P-p38 mitogen-activated protein kinase activation in streptozotocin-induced diabetic rats.
Eur J Pain, 2014 Feb , 18 (162-73).

69

Yang Q et al. Persistent pain after spinal cord injury is maintained by primary afferent activity.
J. Neurosci., 2014 Aug 6 , 34 (10765-9).

70

Bagal SK et al. Recent progress in sodium channel modulators for pain.
Bioorg. Med. Chem. Lett., 2014 Aug 15 , 24 (3690-9).

71

Themistocleous AC et al. The clinical approach to small fibre neuropathy and painful channelopathy.
Pract Neurol, 2014 Apr 28 , ().

72

van den Boogaard M et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression.
J. Clin. Invest., 2014 Apr 1 , 124 (1844-52).

73

Park DS et al. Nav-igating through a complex landscape: SCN10A and cardiac conduction.
J. Clin. Invest., 2014 Apr 1 , 124 (1460-2).

74

Delaney JT et al. Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation.
Europace, 2014 Apr , 16 (485-90).

75

Laedermann CJ et al. Ubiquitylation of voltage-gated sodium channels.
Handb Exp Pharmacol, 2014 , 221 (231-50).

76

Thakur M et al. Defining the nociceptor transcriptome.
Front Mol Neurosci, 2014 , 7 (87).

77

Neishabouri A et al. Saltatory conduction in unmyelinated axons: clustering of Na(+) channels on lipid rafts enables micro-saltatory conduction in C-fibers.
Front Neuroanat, 2014 , 8 (109).

78

Zhao R et al. PKC-NF-κB are involved in CCL2-induced Nav1.8 expression and channel function in dorsal root ganglion neurons.
Biosci. Rep., 2014 , 34 ().

79

Belkouch M et al. Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation.
J Neuroinflammation, 2014 , 11 (45).

80

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

81

Liu XD et al. Functional upregulation of nav1.8 sodium channels on the membrane of dorsal root Ganglia neurons contributes to the development of cancer-induced bone pain.
PLoS ONE, 2014 , 9 (e114623).

82

Lakomá J et al. Pain related channels are differentially expressed in neuronal and non-neuronal cells of glabrous skin of fabry knockout male mice.
PLoS ONE, 2014 , 9 (e108641).

83

Christidis N et al. Expression of 5-HT3 receptors and TTX resistant sodium channels (Na(V)1.8) on muscle nerve fibers in pain-free humans and patients with chronic myofascial temporomandibular disorders.
J Headache Pain, 2014 , 15 (63).

84

Schirmeyer J et al. Exon 11 skipping of SCN10A coding for voltage-gated sodium channels in dorsal root ganglia.
Channels (Austin), 2014 , 8 (210-5).

85

Petersson ME et al. Differential axonal conduction patterns of mechano-sensitive and mechano-insensitive nociceptors--a combined experimental and modelling study.
PLoS ONE, 2014 , 9 (e103556).

86

Minett MS et al. Significant determinants of mouse pain behaviour.
PLoS ONE, 2014 , 9 (e104458).

87

Chiu IM et al. Bacteria activate sensory neurons that modulate pain and inflammation.
Nature, 2013 Sep 5 , 501 (52-7).

88

Chen J et al. Neurological and cellular regulation of visceral hypersensitivity induced by chronic stress and colonic inflammation in rats.
Neuroscience, 2013 Sep 17 , 248 (469-78).

89

Bezzina CR et al. Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Nat. Genet., 2013 Sep , 45 (1044-9).

90

Shen KF et al. Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons.
Exp. Neurol., 2013 Sep , 247 (466-75).

91

Wu Z et al. Full-length membrane-bound tumor necrosis factor-α acts through tumor necrosis factor receptor 2 to modify phenotype of sensory neurons.
Pain, 2013 Sep , 154 (1778-82).

92

Rowe AH et al. Voltage-gated sodium channel in grasshopper mice defends against bark scorpion toxin.
Science, 2013 Oct 25 , 342 (441-6).

93

Argyriou AA et al. Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: results from a prospective multicenter study.
Cancer, 2013 Oct 1 , 119 (3570-7).

94

Zhang XY et al. Gain-of-function mutations in SCN11A cause familial episodic pain.
Am. J. Hum. Genet., 2013 Nov 7 , 93 (957-66).

95

Su YY et al. KIF5B promotes the forward transport and axonal function of the voltage-gated sodium channel Nav1.8.
J. Neurosci., 2013 Nov 6 , 33 (17884-96).

96

Daou I et al. Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
J. Neurosci., 2013 Nov 20 , 33 (18631-40).

97

Zhao ZQ et al. Chronic itch development in sensory neurons requires BRAF signaling pathways.
J. Clin. Invest., 2013 Nov 1 , 123 (4769-80).

98

Yu YQ et al. Activation of tetrodotoxin-resistant sodium channel NaV1.9 in rat primary sensory neurons contributes to melittin-induced pain behavior.
Neuromolecular Med., 2013 Mar , 15 (209-17).

99

Gao B et al. Expression and secretion of functional recombinant μO-conotoxin MrVIB-His-tag in Escherichia coli.
Toxicon, 2013 Jun 27 , 72C (81-89).

100

Liang L et al. Protein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons.
J Pain, 2013 Jun , 14 (638-47).

101

Jiang N et al. Molecular and cellular influences of permethrin on mammalian nociceptors at physiological temperatures.
Neurotoxicology, 2013 Jul , 37 (207-19).

102

Waxman SG Painful Na-channelopathies: an expanding universe.
Trends Mol Med, 2013 Jul , 19 (406-9).

103

Ramachandra R et al. NaV1.8 channels are expressed in large, as well as small, diameter sensory afferent neurons.
Channels (Austin), 2013 Jan 1 , 7 (34-7).

104

Arisawa T et al. Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects.
J. Gastroenterol., 2013 Jan , 48 (73-80).

105

van den Boogaard M et al. From GWAS to function: Genetic variation in sodium channel gene enhancer influences electrical patterning.
Trends Cardiovasc. Med., 2013 Dec 17 , ().

106

Huang J et al. Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
J. Neurosci., 2013 Aug 28 , 33 (14087-97).

107

van Duijvenboden K et al. Gene regulatory elements of the cardiac conduction system.
Brief Funct Genomics, 2013 Aug 22 , ().

108

Abbas N et al. The scorpion toxin Amm VIII induces pain hypersensitivity through gain-of-function of TTX-sensitive Na⁺ channels.
Pain, 2013 Aug , 154 (1204-15).

109

Xie W et al. Knockdown of sodium channel NaV1.6 blocks mechanical pain and abnormal bursting activity of afferent neurons in inflamed sensory ganglia.
Pain, 2013 Aug , 154 (1170-80).

110

Kennedy PG et al. Varicella-Zoster Viruses Associated with Post-Herpetic Neuralgia Induce Sodium Current Density Increases in the ND7-23 Nav-1.8 Neuroblastoma Cell Line.
PLoS ONE, 2013 , 8 (e51570).

111

Bird EV et al. Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas.
Mol Pain, 2013 , 9 (52).

112

Weibel R et al. Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice.
PLoS ONE, 2013 , 8 (e74706).

113

Tsantoulas C et al. Probing functional properties of nociceptive axons using a microfluidic culture system.
PLoS ONE, 2013 , 8 (e80722).

114

Cejudo-Román A et al. The voltage-gated sodium channel nav1.8 is expressed in human sperm.
PLoS ONE, 2013 , 8 (e76084).

115

Zhang Y et al. Effects of (-)-gallocatechin-3-gallate on tetrodotoxin-resistant voltage-gated sodium channels in rat dorsal root ganglion neurons.
Int J Mol Sci, 2013 , 14 (9779-89).

116

Numann RE et al. Letter to the editor on NaV1.8.
Circ. Res., 2012 Sep 28 , 111 (e230; author reply e231).

117

Nozaki C et al. δ-Opioid mechanisms for ADL5747 and ADL5859 effects in mice: analgesia, locomotion, and receptor internalization.
J. Pharmacol. Exp. Ther., 2012 Sep , 342 (799-807).

118

Faber CG et al. Gain-of-function Nav1.8 mutations in painful neuropathy.
Proc. Natl. Acad. Sci. U.S.A., 2012 Nov 20 , 109 (19444-9).

119

Hodgdon KE et al. Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Neuroscience, 2012 Mar 29 , 206 (237-44).

120

Raouf R et al. Sodium channels and mammalian sensory mechanotransduction.
, 2012 Mar 26 , 8 (21).

121

Qiu F et al. Increased expression of tetrodotoxin-resistant sodium channels Nav1.8 and Nav1.9 within dorsal root ganglia in a rat model of bone cancer pain.
Neurosci. Lett., 2012 Mar 23 , 512 (61-6).

122

Tao R et al. [Expression of Nav1.8 in human dental pulp].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2012 Mar , 47 (177-81).

123

Leffler A et al. Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine.
Anesthesiology, 2012 Jun , 116 (1335-46).

124

Bierhaus A et al. Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Nat. Med., 2012 Jun , 18 (926-33).

125

London B Whither art thou, SCN10A, and what art thou doing?
Circ. Res., 2012 Jul 20 , 111 (268-70).

126

Yang T et al. Blocking scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Circ. Res., 2012 Jul 20 , 111 (322-32).

127

Verkerk AO et al. Functional Nav1.8 channels in intracardiac neurons: the link between SCN10A and cardiac electrophysiology.
Circ. Res., 2012 Jul 20 , 111 (333-43).

128

van den Boogaard M et al. Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
J. Clin. Invest., 2012 Jul 2 , 122 (2519-30).

129

Chambers SM et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.
Nat. Biotechnol., 2012 Jul , 30 (715-20).

130

Schuelert N et al. Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis.
, 2012 Jan 7 , 14 (R5).

131

Moon JY et al. The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia.
Anesth. Analg., 2012 Jan , 114 (215-23).

132

Fukuoka T et al. Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation.
Pain, 2012 Jan , 153 (68-79).

133

Shields SD et al. A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis.
Ann. Neurol., 2012 Feb , 71 (186-94).

134

Gaudioso C et al. Menthol pain relief through cumulative inactivation of voltage-gated sodium channels.
Pain, 2012 Feb , 153 (473-84).

135

Gilchrist J et al. Animal toxins can alter the function of Nav1.8 and Nav1.9.
Toxins (Basel), 2012 Aug , 4 (620-32).

136

Ding H et al. Alterations of gene expression of sodium channels in dorsal root ganglion neurons of estrogen receptor knockout (ERKO) mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Endocrine, 2012 Aug , 42 (118-24).

137

Kim YS et al. Expression of transient receptor potential ankyrin 1 in human dental pulp.
J Endod, 2012 Aug , 38 (1087-92).

138

Wu DF et al. PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice.
J. Clin. Invest., 2012 Apr 2 , 122 (1306-15).

139

Hu F et al. 17β-Estradiol regulates the gene expression of voltage-gated sodium channels: role of estrogen receptor α and estrogen receptor β.
Endocrine, 2012 Apr , 41 (274-80).

140

Minett MS et al. Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.
Nat Commun, 2012 , 3 (791).

141

Kao DJ et al. CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Nav1.8 sodium channels in dorsal root ganglion neurons.
J Neuroinflammation, 2012 , 9 (189).

142

Ito A et al. Anti-hyperalgesic effects of calcitonin on neuropathic pain interacting with its peripheral receptors.
Mol Pain, 2012 , 8 (42).

143

Mert T et al. Antinociceptive activities of lidocaine and the nav1.8 blocker a803467 in diabetic rats.
J. Am. Assoc. Lab. Anim. Sci., 2012 , 51 (579-85).

144

Gautron L et al. Genetic tracing of Nav1.8-expressing vagal afferents in the mouse.
J. Comp. Neurol., 2011 Oct 15 , 519 (3085-101).

145

Hoffman EM et al. Potential mechanisms for hypoalgesia induced by anti-nerve growth factor immunoglobulin are identified using autoimmune nerve growth factor deprivation.
Neuroscience, 2011 Oct 13 , 193 (452-65).

146

Blasius AL et al. Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.
Proc. Natl. Acad. Sci. U.S.A., 2011 Nov 29 , 108 (19413-8).

147

Ruangsri S et al. Relationship of axonal voltage-gated sodium channel 1.8 (NaV1.8) mRNA accumulation to sciatic nerve injury-induced painful neuropathy in rats.
J. Biol. Chem., 2011 Nov 18 , 286 (39836-47).

148

Byers MR et al. Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels.
Arch. Oral Biol., 2011 Nov , 56 (1199-220).

149

Franck MC et al. Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse.
, 2011 Mar 14 , ().

150

Shou WT et al. [Role of voltage-sodium channels in neuropathic pain].
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2011 Mar , 40 (217-21).

151

Fukuoka T et al. Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion.
Neurosci. Res., 2011 Jun , 70 (164-71).

152

Liu M et al. The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain.
Pain Med, 2011 Jul , 12 Suppl 3 (S93-9).

153

Widmark J et al. Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.
Mol. Biol. Evol., 2011 Jan , 28 (859-71).

154

Huang ZJ et al. Topical application of compound Ibuprofen suppresses pain by inhibiting sensory neuron hyperexcitability and neuroinflammation in a rat model of intervertebral foramen inflammation.
J Pain, 2011 Jan , 12 (141-52).

155

Ho C et al. Single-cell analysis of sodium channel expression in dorsal root ganglion neurons.
Mol. Cell. Neurosci., 2011 Jan , 46 (159-66).

156

Moraes ER et al. Differential effects of Tityus bahiensis scorpion venom on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium currents.
Neurotox Res, 2011 Jan , 19 (102-14).

157

Chen X et al. TNF-α enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury.
Exp. Neurol., 2011 Feb , 227 (279-86).

158

Belkouch M et al. The chemokine CCL2 increases Nav1.8 sodium channel activity in primary sensory neurons through a Gβγ-dependent mechanism.
J. Neurosci., 2011 Dec 14 , 31 (18381-90).

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