PubMed 25695265

Referenced in Channelpedia wiki pages of: none

Automatically associated channels: TRP , TRPA , TRPA1 , TRPV , TRPV1

Title: Loosening Pain's Grip by Tightening TRPV1-TRPA1 Interactions.

Authors: Andy D Weyer, Cheryl L Stucky

Journal, date & volume: Neuron, 2015 Feb 18 , 85, 661-3

PubMed link:

TRPA1 and TRPV1 are ion channels crucial for pain sensation. In this issue of Neuron, Weng et al. (2015) demonstrate that the activity of TRPA1-TRPV1 heteromers is governed by Tmem100 and that disabling Tmem100 may be a novel pharmacologic strategy to combat pain.