TRPV4

Description: transient receptor potential cation channel, subfamily V, member 4
Gene: Trpv4
Alias: TRPV4

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	59341	12	50311
Mouse	63873	5	36284
Rat	66026	12	38984

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_021625.5	3228
Mouse	NM_022017.3	3247
Rat	NM_023970.1	3211

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	Q9HBA0	871
Mouse	Q9EPK8	871
Rat	Q9ERZ8	871

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NM_001177433.1

2871

NP_001170904.1

764

transcript variant 3

isoform c

NM_001177428.1

3051

NP_001170899.1

824

transcript variant 5

isoform e

NM_147204.2

3012

NP_671737.1

811

transcript variant 2

isoform b

NM_001177431.1

3059

NP_001170902.1

837

transcript variant 4

isoform d

NM_021625.5

3228

NP_067638.3

871

transcript variant 1

isoform a

Predicted

XM_047429295.1

2909

XP_047285251.1

764

transcript variant X9

isoform X9

XM_047429293.1

3089

XP_047285249.1

824

transcript variant X5

isoform X5

XM_047429294.1

3050

XP_047285250.1

811

transcript variant X7

isoform X7

XM_017019774.2

3974

XP_016875263.1

871

transcript variant X3

isoform X3

XM_011538633.3

4021

XP_011536935.2

815

transcript variant X6

isoform X6

XM_011538631.3

4200

XP_011536933.2

875

transcript variant X2

isoform X2

XM_011538632.3

4161

XP_011536934.2

862

transcript variant X4

isoform X4

XM_011538630.3

4341

XP_011536932.2

922

transcript variant X1

isoform X1

XM_011538634.3

3488

XP_011536936.2

793

transcript variant X8

isoform X8

XM_011538635.3

3227

XP_011536937.1

695

transcript variant X10

isoform X10

XM_047429296.1

2942

XP_047285252.1

603

transcript variant X11

isoform X11

XM_054372806.1

2909

XP_054228781.1

764

transcript variant X9

isoform X9

XM_054372802.1

3089

XP_054228777.1

824

transcript variant X5

isoform X5

XM_054372804.1

3050

XP_054228779.1

811

transcript variant X7

isoform X7

XM_054372800.1

3974

XP_054228775.1

871

transcript variant X3

isoform X3

XM_054372803.1

4021

XP_054228778.1

815

transcript variant X6

isoform X6

XM_054372799.1

4200

XP_054228774.1

875

transcript variant X2

isoform X2

XM_054372801.1

4161

XP_054228776.1

862

transcript variant X4

isoform X4

XM_054372798.1

4341

XP_054228773.1

922

transcript variant X1

isoform X1

XM_054372805.1

3488

XP_054228780.1

793

transcript variant X8

isoform X8

XM_054372807.1

3227

XP_054228782.1

695

transcript variant X10

isoform X10

XM_054372808.1

2942

XP_054228783.1

603

transcript variant X11

isoform X11

Known

NM_022017.3

3247

NP_071300.2

871

Predicted

XM_006530432.2

3245

XP_006530495.2

871

transcript variant X1

isoform X1

XM_011248235.1

2464

XP_011246537.1

740

transcript variant X2

isoform X2

XM_036165405.1

1994

XP_036021298.1

592

transcript variant X3

isoform X3

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Post-Translational Modifications

PTM

Position

Type

Modified residue

110

Phosphotyrosine

Modified residue

253

Phosphotyrosine

Modified residue

805

Phosphotyrosine

Modified residue

824

Phosphoserine

Modified residue

110

Phosphotyrosine; by SRC-type Tyr-kinases

Modified residue

253

Phosphotyrosine; by LYN

Modified residue

805

Phosphotyrosine; by SRC-type Tyr-kinases

Modified residue

824

Phosphoserine; by PKC and PKA

Glycosylation

651

N-linked (GlcNAc...) asparagine

Modified residue

110

Phosphotyrosine

Modified residue

253

Phosphotyrosine

Modified residue

805

Phosphotyrosine

Modified residue

824

Phosphoserine

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Structure

TRPV4 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	6148.80	source
Mouse	8245.31	source
Rat	7445.20	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/176/ , accessed on 2025 Nov 10

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