TASK2

1

Veale EL et al. Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels.
Br. J. Pharmacol., 2016 May , 173 (1639-52).

2

Ohya S Physiological Role of K(+) Channels in the Regulation of T Cell Function.
Yakugaku Zasshi, 2016 , 136 (479-83).

3

Reed AP et al. Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy.
PLoS ONE, 2016 , 11 (e0156456).

4

Schulte-Mecklenbeck A et al. The two-pore domain K2 P channel TASK2 drives human NK-cell proliferation and cytolytic function.
Eur. J. Immunol., 2015 Sep , 45 (2602-14).

5

Göb E et al. The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration.
Pflugers Arch., 2015 May , 467 (973-87).

6

López-Cayuqueo KI et al. TASK-2 K₂p K⁺ channel: thoughts about gating and its fitness to physiological function.
Pflugers Arch., 2015 May , 467 (1043-53).

7

Bayliss DA et al. The role of pH-sensitive TASK channels in central respiratory chemoreception.
Pflugers Arch., 2015 May , 467 (917-29).

8

Ehling P et al. The CNS under pathophysiologic attack--examining the role of K₂p channels.
Pflugers Arch., 2015 May , 467 (959-72).

9

Kumar NN et al. PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.
Science, 2015 Jun 12 , 348 (1255-60).

10

Endo K et al. Molecular identification of the dominant-negative, splicing isoform of the two-pore domain K(+) channel K(2P)5.1 in lymphoid cells and enhancement of its expression by splicing inhibition.
Biochem. Pharmacol., 2015 Dec 1 , 98 (440-52).

11

Cazals Y et al. KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing.
Nat Commun, 2015 , 6 (8780).

12

Bittner S et al. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms.
Int J Mol Sci, 2015 , 16 (16880-96).

13

Shin DH et al. HIF-1α-mediated upregulation of TASK-2 K⁺ channels augments Ca²⁺ signaling in mouse B cells under hypoxia.
J. Immunol., 2014 Nov 15 , 193 (4924-33).

14

Hao X et al. 17β-estradiol downregulated the expression of TASK-1 channels in mouse neuroblastoma N2A cells.
J. Membr. Biol., 2014 Mar , 247 (273-9).

15

Peña-Münzenmayer G et al. Zebrafish and mouse TASK-2 K(+) channels are inhibited by increased CO2 and intracellular acidification.
Pflugers Arch., 2014 Jul , 466 (1317-27).

16

Perathoner S et al. Bioelectric signaling regulates size in zebrafish fins.
PLoS Genet., 2014 Jan , 10 (e1004080).

17

Lenzini L et al. Lower expression of the TWIK-related acid-sensitive K+ channel 2 (TASK-2) gene is a hallmark of aldosterone-producing adenoma causing human primary aldosteronism.
J. Clin. Endocrinol. Metab., 2014 Apr , 99 (E674-82).

18

Toncheva D et al. NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy.
Biomed Res Int, 2014 , 2014 (920723).

19

Añazco C et al. G protein modulation of K2P potassium channel TASK-2 : a role of basic residues in the C terminus domain.
Pflugers Arch., 2013 Dec , 465 (1715-26).

20

Kirkegaard SS et al. KCNK5 is functionally down-regulated upon long-term hypotonicity in Ehrlich ascites tumor cells.
Cell. Physiol. Biochem., 2013 , 32 (1238-46).