TWIK1

1

Jorgensen C et al. Lateral Fenestrations in K(+)-Channels Explored Using Molecular Dynamics Simulations.
Mol. Pharm., 2016 May 26 , ().

2

Wiedmann F et al. Therapeutic targeting of two-pore-domain potassium (K2P) channels in the cardiovascular system.
Clin. Sci., 2016 May 1 , 130 (643-50).

3

Christensen AH et al. The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size.
J. Mol. Cell. Cardiol., 2016 Apr 19 , 97 (24-35).

4

Yeon JT et al. KCNK1 inhibits osteoclastogenesis by blocking the Ca2+ oscillation and JNK-NFATc1 signaling axis.
J. Cell. Sci., 2015 Sep 15 , 128 (3411-9).

5

Enyedi P et al. Properties, regulation, pharmacology, and functions of the K₂p channel, TRESK.
Pflugers Arch., 2015 May , 467 (945-58).

6

Decher N et al. The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.
Pflugers Arch., 2015 May , 467 (1055-67).

7

Mathie A et al. Two-pore domain potassium channels: potential therapeutic targets for the treatment of pain.
Pflugers Arch., 2015 May , 467 (931-43).

8

Dong YY et al. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Science, 2015 Mar 13 , 347 (1256-9).

9

Aryal P et al. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel.
Channels (Austin), 2015 Jan 2 , 9 (44-9).

10

Baruteau AE et al. Inherited progressive cardiac conduction disorders.
Curr. Opin. Cardiol., 2015 Jan , 30 (33-9).

11

Trick JL et al. Molecular simulation studies of hydrophobic gating in nanopores and ion channels.
Biochem. Soc. Trans., 2015 Apr 1 , 43 (146-50).

12

Kubota K et al. Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Apr 1 , 308 (G579-90).

13

Stephens RF et al. Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels.
Front Physiol, 2015 , 6 (153).

14

Rhodin K et al. Chronic periodontitis genome-wide association studies: gene-centric and gene set enrichment analyses.
J. Dent. Res., 2014 Sep , 93 (882-90).

15

Chen H et al. Altered and dynamic ion selectivity of K+ channels in cell development and excitability.
Trends Pharmacol. Sci., 2014 Sep , 35 (461-9).

16

Burgos P et al. Differential expression of two-pore domain potassium channels in rat cerebellar granule neurons.
Biochem. Biophys. Res. Commun., 2014 Oct 31 , 453 (754-60).

17

Czirják G et al. The LQLP calcineurin docking site is a major determinant of the calcium-dependent activation of human TRESK background K+ channel.
J. Biol. Chem., 2014 Oct 24 , 289 (29506-18).

18

Bichet D et al. Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2.
Pflugers Arch., 2014 Oct 24 , ().

19

He L et al. Association of variants in KCNK17 gene with ischemic stroke and cerebral hemorrhage in a Chinese population.
J Stroke Cerebrovasc Dis, 2014 Oct , 23 (2322-7).

20

Rainero I et al. KCNK18 (TRESK) genetic variants in Italian patients with migraine.
Headache, 2014 Oct , 54 (1515-22).

21

Rahm AK et al. Functional characterization of zebrafish K2P18.1 (TRESK) two-pore-domain K+ channels.
Naunyn Schmiedebergs Arch. Pharmacol., 2014 Mar , 387 (291-300).

22

Zappia KJ et al. Cold hypersensitivity increases with age in mice with sickle cell disease.
Pain, 2014 Jun 3 , ().

23

Bruner JK et al. Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.
Eur. J. Pharmacol., 2014 Jun 24 , ().

24

Friedrich C et al. Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.
EMBO Mol Med, 2014 Jul , 6 (937-51).

25

Feliciangeli S et al. The family of K2P channels: salient structural and functional properties.
J. Physiol. (Lond.), 2014 Dec 22 , ().

26

Seyler C et al. Vernakalant activates human cardiac K(2P)17.1 background K(+) channels.
Biochem. Biophys. Res. Commun., 2014 Aug 29 , 451 (415-20).

27

Nishizuka M et al. KCNK10, a tandem pore domain potassium channel, is a regulator of mitotic clonal expansion during the early stage of adipocyte differentiation.
Int J Mol Sci, 2014 , 15 (22743-56).

28

Vanegas JM et al. Force transduction and lipid binding in MscL: a continuum-molecular approach.
PLoS ONE, 2014 , 9 (e113947).

29

Aryal P et al. A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.
Nat Commun, 2014 , 5 (4377).

30

Enyedi P et al. Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.
PLoS ONE, 2014 , 9 (e97854).

31

Yarishkin O et al. TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus.
Mol Brain, 2014 , 7 (80).

32

Schneider ER et al. Temperature sensitivity of two-pore (K2P) potassium channels.
Curr Top Membr, 2014 , 74 (113-33).

33

Hwang EM et al. A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes.
Nat Commun, 2014 , 5 (3227).

34

Sehgal SA et al. Pharmacoinformatics elucidation of potential drug targets against migraine to target ion channel protein KCNK18.
Drug Des Devel Ther, 2014 , 8 (571-81).

35

Maher BH et al. Analysis of 3 common polymorphisms in the KCNK18 gene in an Australian Migraine case-control cohort.
Gene, 2013 Oct 10 , 528 (343-6).

36

Pollema-Mays SL et al. Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain model.
Mol. Cell. Neurosci., 2013 Nov , 57 (1-9).

37

Innamaa A et al. Expression and effects of modulation of the K2P potassium channels TREK-1 (KCNK2) and TREK-2 (KCNK10) in the normal human ovary and epithelial ovarian cancer.
Clin Transl Oncol, 2013 Nov , 15 (910-8).