Kir3.1

1

Morishima M et al. Atrial Fibrillation-Mediated Upregulation of miR-30d Regulates Myocardial Electrical Remodeling of the G-Protein-Gated K(+) Channel, IK.ACh.
Circ. J., 2016 May 25 , 80 (1346-55).

2

Swale DR et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
ACS Chem Neurosci, 2016 May 24 , ().

3

Chin C et al. Identification and Localization of Gold Nanoparticles in Potassium Ion Pores: Implications for Kir Blockade.
Cardiol Ther, 2016 Jun , 5 (101-8).

4

Bragança B et al. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria.
Front Pharmacol, 2016 , 7 (45).

5

Touhara KK et al. The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers.
Elife, 2016 , 5 ().

6

Holmes AP et al. A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity.
PLoS ONE, 2016 , 11 (e0154077).

7

Ehrich JM et al. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons.
J. Neurosci., 2015 Sep 16 , 35 (12917-31).

8

Nagi K et al. Kir3 channels undergo arrestin-dependant internalization following delta opioid receptor activation.
Cell. Mol. Life Sci., 2015 Sep , 72 (3543-57).

9

Bukiya AN et al. Cholesterol increases the open probability of cardiac KACh currents.
Biochim. Biophys. Acta, 2015 Oct , 1848 (2406-13).

10

Yakubovich D et al. A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.
PLoS Comput. Biol., 2015 Nov , 11 (e1004598).

11

Kotecki L et al. GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner.
J. Neurosci., 2015 May 6 , 35 (7131-42).

12

Langford DJ et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery.
Pain, 2015 Mar , 156 (371-80).

13

Robertson DN et al. Design and construction of conformational biosensors to monitor ion channel activation: A prototype FlAsH/BRET-approach to Kir3 channels.
Methods, 2015 Jul 22 , ().

14

Devalla HD et al. Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
EMBO Mol Med, 2015 Feb 19 , ().

15

Amaral AC et al. Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex.
Neuroscience, 2015 Feb 12 , 286 (79-86).

16

Xiong WH et al. Voriconazole, an antifungal triazol that causes visual side effects, is an inhibitor of TRPM1 and TRPM3 channels.
Invest. Ophthalmol. Vis. Sci., 2015 Feb , 56 (1367-73).

17

Henn MC et al. Adenosine Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide.
J Am Heart Assoc, 2015 Aug , 4 (e002016).

18

Lyu C et al. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy.
Mol Pain, 2015 , 11 (44).

19

Montalbano A et al. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
PLoS ONE, 2015 , 10 (e0140369).

20

Kanbara T et al. Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model.
Neurosci. Lett., 2014 Sep 19 , 580 (119-24).

21

Kupferman JV et al. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.
Cell, 2014 Sep 11 , 158 (1335-47).

22

Kuppusamy M et al. A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
J. Clin. Endocrinol. Metab., 2014 Sep , 99 (E1765-73).

23

Wen W et al. Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas.
Bioorg. Med. Chem. Lett., 2014 Nov 1 , 24 (5102-6).

24

Kienitz MC et al. Differential effects of genetically-encoded Gβγ scavengers on receptor-activated and basal Kir3.1/Kir3.4 channel current in rat atrial myocytes.
Cell. Signal., 2014 Jun , 26 (1182-92).

25

Raphemot R et al. Direct activation of β-cell KATP channels with a novel xanthine derivative.
Mol. Pharmacol., 2014 Jun , 85 (858-65).

26

Wydeven N et al. Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jul 22 , 111 (10755-60).

27

Tanwar V et al. Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the signaling pathway.
Stem Cells, 2014 Jul , 32 (1774-88).

28

Langford DJ et al. Variations in Potassium Channel Genes Are Associated With Breast Pain in Women Prior to Breast Cancer Surgery.
J. Neurogenet., 2014 Jan 7 , ().

29

Liang B et al. G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization.
Cardiovasc. Res., 2014 Jan 1 , 101 (175-84).

30

Chung MK et al. Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.
Eur J Pain, 2014 Jan , 18 (29-38).

31

Kahanovitch U et al. Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.
J. Physiol. (Lond.), 2014 Dec 15 , 592 (5373-90).

32

Farhy Tselnicker I et al. Dual regulation of G proteins and the G-protein-activated K+ channels by lithium.
Proc. Natl. Acad. Sci. U.S.A., 2014 Apr 1 , 111 (5018-23).

33

Kumar M et al. Focus on Kir7.1: physiology and channelopathy.
Channels (Austin), 2014 , 8 (488-95).

34

Treuer AV et al. NOS1AP modulates intracellular Ca(2+) in cardiac myocytes and is up-regulated in dystrophic cardiomyopathy.
Int J Physiol Pathophysiol Pharmacol, 2014 , 6 (37-46).

35

Ramos-Hunter SJ et al. Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators.
Bioorg. Med. Chem. Lett., 2013 Sep 15 , 23 (5195-8).

36

Li X et al. Millimeter wave promotes the synthesis of extracellular matrix and the proliferation of chondrocyte by regulating the voltage-gated K(+) channel.
J. Bone Miner. Metab., 2013 Nov 8 , ().

37

Saenz del Burgo L et al. Chronic effects of corticosterone on GIRK1-3 subunits and 5-HT1A receptor expression in rat brain and their reversal by concurrent fluoxetine treatment.
Eur Neuropsychopharmacol, 2013 Mar , 23 (229-39).

38

Kaufmann K et al. ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice.
ACS Chem Neurosci, 2013 Jun 13 , ().

39

Zylbergold P et al. A novel, radiolabel-free pulse chase strategy to study Kir3 channel ontogeny.
J. Recept. Signal Transduct. Res., 2013 Jun , 33 (144-52).

40

Kiss T et al. Identification of diterpene alkaloids from Aconitum napellus subsp. firmum and GIRK channel activities of some Aconitum alkaloids.
Fitoterapia, 2013 Jul 19 , ().

41

Ravens U et al. Atrial selectivity of antiarrhythmic drugs.
J. Physiol. (Lond.), 2013 Jul 16 , ().

42

Ford J et al. Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial Selective Kv1.5/IKur Inhibitor.
J. Cardiovasc. Pharmacol., 2013 Jan 29 , ().

43

Richard-Lalonde M et al. Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.
Mol. Pharmacol., 2013 Feb , 83 (416-28).

44

Bingen BO et al. Atrium-specific Kir3.x determines inducibility, dynamics, and termination of fibrillation by regulating restitution-driven alternans.
Circulation, 2013 Dec 24 , 128 (2732-44).

45

Bruehl S et al. Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.
Pain, 2013 Dec , 154 (2853-9).

46

Wen W et al. Discovery of 'molecular switches' within a GIRK activator scaffold that afford selective GIRK inhibitors.
Bioorg. Med. Chem. Lett., 2013 Aug 15 , 23 (4562-6).

47

Mahajan R et al. A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.
Sci Signal, 2013 Aug 13 , 6 (ra69).

48

Tsai WC et al. Ablation of the androgen receptor gene modulates atrial electrophysiology and arrhythmogenesis with calcium protein dysregulation.
Endocrinology, 2013 Aug , 154 (2833-42).

49

Treiber F et al. Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.
Biochim. Biophys. Acta, 2013 Apr , 1828 (1214-21).

50

Holmegard HN et al. Genetic variation in the parasympathetic signaling pathway in patients with reflex syncope.
Genet. Mol. Res., 2013 , 12 (2601-10).

51

Murthy R et al. Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1.
Mol Brain, 2013 , 6 (30).

52

Okada M et al. Negative inotropic effect of carbachol and interaction between acetylcholine receptor-operated potassium channel (K.ACh Channel) and GTP binding protein in mouse isolated atrium -- a novel methodological trial.
J. Vet. Med. Sci., 2013 , 75 (377-80).

53

Atkinson AJ et al. Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.
J Am Heart Assoc, 2013 , 2 (e000246).

54

Kim S et al. Paradoxical contribution of SK3 and GIRK channels to the activation of mouse vomeronasal organ.
Nat. Neurosci., 2012 Sep , 15 (1236-44).

55

Meng XY et al. The molecular mechanism by which PIP(2) opens the intracellular G-loop gate of a Kir3.1 channel.
Biophys. J., 2012 May 2 , 102 (2049-59).

56

Kloukina V et al. G-protein-gated inwardly rectifying K+ channel 4 (GIRK4) immunoreactivity in chemically defined neurons of the hypothalamic arcuate nucleus that control body weight.
J. Chem. Neuroanat., 2012 May , 44 (14-23).

57

Yamada K et al. Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population.
Hum. Genet., 2012 Mar , 131 (443-51).

58

Deng W et al. Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ.
J. Biol. Chem., 2012 Feb 10 , 287 (4925-35).

59

Wydeven N et al. Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity.
Proc. Natl. Acad. Sci. U.S.A., 2012 Dec 26 , 109 (21492-7).

60

Mase Y et al. Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by the i/o-family G protein α subunit (Gαi/o).
, 2012 Apr 16 , ().

61

Wu J et al. Regulatory mechanisms underlying the modulation of GIRK1/GIRK4 heteromeric channels by P2Y receptors.
Pflugers Arch., 2012 Apr , 463 (625-33).

62

Caro LN et al. Engineering of an artificial light-modulated potassium channel.
PLoS ONE, 2012 , 7 (e43766).

63

Lü Q et al. Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.
Mol Med Report, 2011 Sep-Oct , 4 (941-5).

64

Whorton MR et al. Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
Cell, 2011 Sep 30 , 147 (199-208).

65

Berlin S et al. Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits.
J. Biol. Chem., 2011 Sep 23 , 286 (33223-35).

66

Loscalzo LM et al. Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents.
Pharmacol. Biochem. Behav., 2011 Sep , 99 (333-41).

67

Chen PC et al. Syntaxin 1A regulates surface expression of beta-cell ATP-sensitive potassium channels.
Am. J. Physiol., Cell Physiol., 2011 Mar , 300 (C506-16).

68

Wu Y et al. GABAB receptor-mediated tonic inhibition of noradrenergic A7 neurons in the rat.
J. Neurophysiol., 2011 Jun , 105 (2715-28).

69

Machida T et al. Effects of a highly selective acetylcholine-activated K+ channel blocker on experimental atrial fibrillation.
Circ Arrhythm Electrophysiol, 2011 Feb , 4 (94-102).

70

Fernandez-Alacid L et al. Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain.
Eur. J. Neurosci., 2011 Dec , 34 (1724-36).

71

Jo HY et al. Kir3.1 channel is functionally involved in TLR4-mediated signaling.
Biochem. Biophys. Res. Commun., 2011 Apr 22 , 407 (687-91).

72

Kobayashi T et al. Inhibition of g protein-activated inwardly rectifying k channels by different classes of antidepressants.
PLoS ONE, 2011 , 6 (e28208).

73

Jabbari J et al. Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians.
Cardiology, 2011 , 118 (116-20).

74

White MD et al. A Molecular Toolbox for Rapid Generation of Viral Vectors to Up- or Down-Regulate Neuronal Gene Expression in vivo.
Front Mol Neurosci, 2011 , 4 (8).

75

Ciruela F et al. Evidence for oligomerization between GABA(B) receptors and GIRK channels containing the GIRK1 and GIRK3 subunits.
, 2010 Sep 16 , ().

76

Arora D et al. Altered neurotransmission in the mesolimbic reward system of Girk mice.
J. Neurochem., 2010 Sep 1 , 114 (1487-97).

77

Farhang B et al. The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons.
Neuropharmacology, 2010 Sep , 59 (190-200).

78

Voigt N et al. Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation.
Circ Arrhythm Electrophysiol, 2010 Oct 1 , 3 (472-80).

79

Yokogawa M et al. NMR analyses of the G{beta}{gamma} binding and conformational rearrangements of the cytoplasmic pore of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).
, 2010 Nov 12 , ().

80

Noujaim SF et al. Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.
, 2010 Jun 28 , ().

81

Wagner V et al. Cloning and characterisation of GIRK1 variants resulting from alternative RNA editing of the KCNJ3 gene transcript in a human breast cancer cell line.
J. Cell. Biochem., 2010 Jun 1 , 110 (598-608).

82

Kobayashi T et al. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine.
Neuropsychopharmacology, 2010 Jun , 35 (1560-9).

83

Nobles M et al. HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.
Pflugers Arch., 2010 Jun , 460 (99-108).

84

Layouni S et al. Genetic linkage study of an autosomal recessive form of juvenile myoclonic epilepsy in a consanguineous Tunisian family.
Epilepsy Res., 2010 Jun , 90 (33-8).

85

Kleene R et al. Functional consequences of the interactions between the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB and the inwardly rectifying K+ channel Kir3.3.
, 2010 Jul 6 , ().

86

Berlin S et al. G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK).
J. Biol. Chem., 2010 Feb 26 , 285 (6179-85).

87

Leal-Pinto E et al. Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers.
J. Biol. Chem., 2010 Dec 17 , 285 (39790-800).

88

Walsh KB A real-time screening assay for GIRK1/4 channel blockers.
J Biomol Screen, 2010 Dec , 15 (1229-37).

89

Ponce-Balbuena D et al. Tamoxifen inhibits cardiac ATP-sensitive and acetylcholine-activated K+ currents in part by interfering with phosphatidylinositol 4,5-bisphosphate-channel interaction.
J. Pharmacol. Sci., 2010 , 113 (66-75).

90

Balana B et al. Mutagenesis and functional analysis of ion channels heterologously expressed in Mammalian cells.
J Vis Exp, 2010 , ().

91

Holmegard HN et al. Genetic variation in the inwardly rectifying K channel subunits KCNJ3 (GIRK1) and KCNJ5 (GIRK4) in patients with sinus node dysfunction.
Cardiology, 2010 , 115 (176-81).

92

Osawa M et al. Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel.
J. Biol. Chem., 2009 Sep 18 , 284 (26117-26).

93

Stansfeld PJ et al. PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.
Biochemistry, 2009 Nov 24 , 48 (10926-33).

94

Müllner C et al. Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.
FEBS J., 2009 Nov , 276 (6218-26).

95

Maguy A et al. Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure.
Circ. Res., 2009 May 8 , 104 (1113-22).

96

Ishihara K et al. Heteromeric assembly of inward rectifier channel subunit Kir2.1 with Kir3.1 and with Kir3.4.
Biochem. Biophys. Res. Commun., 2009 Mar 20 , 380 (832-7).

97

Fernández-Alacid L et al. Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.
J. Neurochem., 2009 Jun 22 , ().

98

Yokogawa M et al. Backbone resonance assignments for the cytoplasmic regions of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).
Biomol NMR Assign, 2009 Jun , 3 (125-8).

99

Rusinova R et al. Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunit.
Pflugers Arch., 2009 Jun , 458 (303-14).

100

Park HJ et al. Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.
Circ. Res., 2009 Jul 31 , 105 (287-94).

101

Rubinstein M et al. Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.
J. Physiol. (Lond.), 2009 Jul 15 , 587 (3473-91).

102

Chung HJ et al. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels.
Proc. Natl. Acad. Sci. U.S.A., 2009 Jan 13 , 106 (629-34).

103

Newbury DF et al. Mapping of partially overlapping de novo deletions across an autism susceptibility region (AUTS5) in two unrelated individuals affected by developmental delays with communication impairment.
Am. J. Med. Genet. A, 2009 Feb 15 , 149A (588-97).

104

Brevet M et al. Deregulation of 2 potassium channels in pancreas adenocarcinomas: implication of KV1.3 gene promoter methylation.
Pancreas, 2009 Aug , 38 (649-54).

105

Zhang C et al. The single nucleotide polymorphisms of Kir3.4 gene and their correlation with lone paroxysmal atrial fibrillation in Chinese Han population.
Heart Lung Circ, 2009 Aug , 18 (257-61).

106

Robitaille M et al. Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes.
Cell. Signal., 2009 Apr , 21 (488-501).

107

Hong CM et al. Effects of autoantibodies against M2 muscarinic acetylcholine receptors on rabbit atria in vivo.
Cardiology, 2009 , 112 (180-7).

108

Yang D et al. Expression of inwardly rectifying potassium channel subunits in native human retinal pigment epithelium.
Exp. Eye Res., 2008 Sep , 87 (176-83).

109

Hernandez CC et al. A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.
J. Gen. Physiol., 2008 Sep , 132 (361-81).

110

Saenz del Burgo L et al. Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.
J. Comp. Neurol., 2008 Oct 20 , 510 (581-606).

111

Sosulina L et al. Neuropeptide Y activates a G-protein-coupled inwardly rectifying potassium current and dampens excitability in the lateral amygdala.
Mol. Cell. Neurosci., 2008 Nov , 39 (491-8).

112

Klose A et al. 1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U73122) selectively inhibits Kir3 and BK channels in a phospholipase C-independent fashion.
Mol. Pharmacol., 2008 Nov , 74 (1203-14).

113

Grasser E et al. Subunit stoichiometry of heterologously expressed G-protein activated inwardly rectifying potassium channels analysed by fluorescence intensity ratio measurement.
Pflugers Arch., 2008 Mar , 455 (1017-24).

114

Perry CA et al. Predisposition to late-onset obesity in GIRK4 knockout mice.
Proc. Natl. Acad. Sci. U.S.A., 2008 Jun 10 , 105 (8148-53).

115

Pravetoni M et al. Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.
Genes Brain Behav., 2008 Jul , 7 (523-31).

116

Park HJ et al. Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.
J. Clin. Invest., 2008 Jan , 118 (259-71).

117

Voigt N et al. Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes.
Cardiovasc. Res., 2008 Jan , 77 (35-43).

118

Hashimoto N et al. Characterization of in vivo and in vitro electrophysiological and antiarrhythmic effects of a novel IKACh blocker, NIP-151: a comparison with an IKr-blocker dofetilide.
J. Cardiovasc. Pharmacol., 2008 Feb , 51 (162-9).

119

Robertson JL et al. Long-pore electrostatics in inward-rectifier potassium channels.
J. Gen. Physiol., 2008 Dec , 132 (613-32).

120

Ehrlich JR Inward rectifier potassium currents as a target for atrial fibrillation therapy.
J. Cardiovasc. Pharmacol., 2008 Aug , 52 (129-35).

121

Brevet M et al. Expression of K+ channels in normal and cancerous human breast.
Histol. Histopathol., 2008 Aug , 23 (965-72).

122

Lin YW et al. Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism.
J. Biol. Chem., 2008 Apr 4 , 283 (9146-56).

123

Aguado C et al. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum.
J. Neurochem., 2008 Apr , 105 (497-511).

124

Thomas AM et al. Determination of phosphoinositide binding to K(+) channel subunits using a protein-lipid overlay assay.
Methods Mol. Biol., 2008 , 491 (103-11).

125

Beckmann C et al. G protein-activated (GIRK) current in rat ventricular myocytes is masked by constitutive inward rectifier current (I(K1)).
Cell. Physiol. Biochem., 2008 , 21 (259-68).

126

Lopes CM et al. Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels.
Channels (Austin), 2007 Mar-Apr , 1 (124-34).

127

Inanobe A et al. Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
Channels (Austin), 2007 Jan-Feb , 1 (39-45).

128

Nishida M et al. Crystal structure of a Kir3.1-prokaryotic Kir channel chimera.
EMBO J., 2007 Sep 5 , 26 (4005-15).

129

Nikolov EN et al. Dynamic integration of alpha-adrenergic and cholinergic signals in the atria: role of G protein-regulated inwardly rectifying K+ channels.
J. Biol. Chem., 2007 Sep 28 , 282 (28669-82).

130

Lucarini N et al. Genetic polymorphisms and idiopathic generalized epilepsies.
Pediatr. Neurol., 2007 Sep , 37 (157-64).

131

Genini S et al. Analysis and mapping of CACNB4, CHRNA1, KCNJ3, SCN2A and SPG4, physiological candidate genes for porcine congenital progressive ataxia and spastic paresis.
J. Anim. Breed. Genet., 2007 Oct , 124 (269-76).

132

Mintert E et al. Generation of a constitutive Na+-dependent inward-rectifier current in rat adult atrial myocytes by overexpression of Kir3.4.
J. Physiol. (Lond.), 2007 Nov 15 , 585 (3-13).

133

Wedemeyer C et al. Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes.
Eur. J. Pharmacol., 2007 May 21 , 562 (165-73).

134

Eulitz D et al. Heterogeneous distribution of kir3 potassium channel proteins within dopaminergic neurons in the mesencephalon of the rat brain.
Cell. Mol. Neurobiol., 2007 May , 27 (285-302).

135

Haider S et al. Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.
Biochemistry, 2007 Mar 27 , 46 (3643-52).

136

Kobayashi T et al. Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes.
Toxicol In Vitro, 2007 Jun , 21 (656-64).

137

Gaborit N et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
J. Physiol. (Lond.), 2007 Jul 15 , 582 (675-93).

138

Hara K et al. Inhibitory effect of gabapentin on N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
, 2007 Jan , 51 (122-8).

139

Harrell MD et al. Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.
Physiol. Genomics, 2007 Feb 12 , 28 (273-83).

140

Calloe K et al. Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.
Biochem. Biophys. Res. Commun., 2007 Dec 28 , 364 (889-95).

141

Kawano T et al. Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.
Mol. Pharmacol., 2007 Apr , 71 (1179-84).

142

Steinecker B et al. The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J. Recept. Signal Transduct. Res., 2007 , 27 (369-82).

143

Marker CL et al. Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels.
J. Neurosci., 2006 Nov 22 , 26 (12251-9).

144

Jaén C et al. RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling.
J. Biol. Chem., 2006 Nov 10 , 281 (34549-60).

145

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine.
J. Pharmacol. Sci., 2006 Nov , 102 (278-87).

146

Iwasaki YK et al. A method for the simultaneous analysis of mRNA levels of multiple cardiac ion channels with a multi-probe RNase protection assay.
, 2006 Nov , 8 (1011-5).

147

Del Re AM et al. Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes.
Brain Res., 2006 May 4 , 1087 (75-82).

148

Thomas AM et al. Differential phosphoinositide binding to components of the G protein-gated K+ channel.
J. Membr. Biol., 2006 May , 211 (43-53).

149

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
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