TRPV3

1

McEntire DM et al. Pain transduction: a pharmacologic perspective.
Expert Rev Clin Pharmacol, 2016 May 23 , (1-12).

2

Li C et al. Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3.
Traffic, 2016 Jan 27 , ().

3

Wu SW et al. Genetic and pharmacological evidence for low abundance TRPV3 expression in primary vagal afferent neurons.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2016 Feb 3 , (ajpregu.00366.2015).

4

Lo IC et al. TRPV3 Channel Negatively Regulates Cell Cycle Progression and Safeguards the Pluripotency of Embryonic Stem Cells.
J. Cell. Physiol., 2016 Feb , 231 (403-13).

5

Murphy TV et al. TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats.
Vascul. Pharmacol., 2016 Apr 9 , ().

6

Singh U et al. Transient receptor potential vanilloid (TRPV3) in the ventral tegmental area of rat: Role in modulation of the mesolimbic-dopamine reward pathway.
Neuropharmacology, 2016 Apr 12 , ().

7

Wei ZL et al. Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.
Bioorg. Med. Chem. Lett., 2015 Sep 15 , 25 (4011-5).

8

Sozucan Y et al. TRP genes family expression in colorectal cancer.
Exp. Oncol., 2015 Sep , 37 (208-12).

9

Rajasekhar P et al. P2Y1 receptor activation of the TRPV4 ion channel enhances purinergic signaling in satellite glial cells.
J. Biol. Chem., 2015 Oct 16 , ().

10

Liu B et al. The Xenopus tropicalis orthologue of TRPV3 is heat sensitive.
J. Gen. Physiol., 2015 Oct 12 , ().

11

Billen B et al. Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes As Revealed by Intrinsic Tryptophan Fluorescence Quenching.
J. Biol. Chem., 2015 Mar 31 , ().

12

He Y et al. A gain-of-function mutation in TRPV3 causes focal palmoplantar keratoderma in a Chinese family.
J. Invest. Dermatol., 2015 Mar , 135 (907-9).

13

Cheung SY et al. Activation of transient receptor potential vanilloid 3 channel suppresses adipogenesis.
Endocrinology, 2015 Jun , 156 (2074-86).

14

Lynch VJ et al. Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic.
Cell Rep, 2015 Jul 14 , 12 (217-28).

15

Ogurtsova EK et al. New Derivatives of Natural Acyclic Guanidine Alkaloids with TRPV Receptor-Regulating Properties.
Nat Prod Commun, 2015 Jul , 10 (1171-3).

16

Zhu Y et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Br. J. Pharmacol., 2015 Jul , 172 (3495-509).

17

Karttunen S et al. Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
J. Cell. Sci., 2015 Jan 15 , 128 (225-31).

18

Raffai G et al. Vanillin and vanillin analogs relax porcine coronary and basilar arteries by inhibiting L-type Ca2+ channels.
J. Pharmacol. Exp. Ther., 2015 Jan , 352 (14-22).

19

Aijima R et al. The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.
FASEB J., 2015 Jan , 29 (182-92).

20

Yang YS et al. Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus.
Acta Derm. Venereol., 2015 Jan , 95 (20-4).

21

Pires PW et al. Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.
Am. J. Physiol. Heart Circ. Physiol., 2015 Dec 15 , 309 (H2031-41).

22

Nozadze I et al. Role of thermo TRPA1 and TRPV1 channels in heat, cold, and mechanical nociception of rats.
Behav Pharmacol, 2015 Aug 13 , ().

23

Son GY et al. Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.
Arch. Oral Biol., 2015 Apr , 60 (526-32).

24

Ma L et al. Nicotinic Acid is a Common Regulator of Heat-Sensing TRPV1-4 Ion Channels.
Sci Rep, 2015 , 5 (8906).

25

Somogyi CS et al. Polymodal Transient Receptor Potential Vanilloid (TRPV) Ion Channels in Chondrogenic Cells.
Int J Mol Sci, 2015 , 16 (18412-38).

26

Carson C et al. Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
PLoS ONE, 2015 , 10 (e0127498).

27

Feketa VV et al. Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents.
PLoS ONE, 2015 , 10 (e0141994).

28

Duchatelet S et al. Olmsted syndrome: clinical, molecular and therapeutic aspects.
Orphanet J Rare Dis, 2015 , 10 (33).

29

Fusi C et al. Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer.
J. Invest. Dermatol., 2014 Sep , 134 (2408-17).

30

Deering-Rice CE et al. Drofenine: A 2-APB Analogue with Greater Selectivity for Human TRPV3.
Pharmacol Res Perspect, 2014 Oct , 2 (e00062).

31

Holzer P et al. The pharmacology of TRP channels.
Br. J. Pharmacol., 2014 May , 171 (2469-73).

32

Kaneko Y et al. Transient receptor potential (TRP) channels: a clinical perspective.
Br. J. Pharmacol., 2014 May , 171 (2474-507).

33

Grubisha O et al. Pharmacological profiling of the TRPV3 channel in recombinant and native assays.
Br. J. Pharmacol., 2014 May , 171 (2631-44).

34

Duchatelet S et al. A new TRPV3 missense mutation in a patient with Olmsted syndrome and erythromelalgia.
JAMA Dermatol, 2014 Mar , 150 (303-6).

35

Klein AH et al. Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.
Neuroscience, 2014 Jun 20 , 271 (45-55).

36

Eytan O et al. Olmsted syndrome caused by a homozygous recessive mutation in TRPV3.
J. Invest. Dermatol., 2014 Jun , 134 (1752-4).

37

Kariminejad A et al. Olmsted syndrome in an Iranian boy with a new de novo mutation in TRPV3.
Clin. Exp. Dermatol., 2014 Jun , 39 (492-5).

38

Klein AS et al. Cholesterol sensitises the transient receptor potential channel TRPV3 to lower temperatures and activator concentrations.
Cell Calcium, 2014 Jan , 55 (59-68).

39

Marics I et al. Acute Heat-Evoked Temperature Sensation Is Impaired but Not Abolished in Mice Lacking TRPV1 and TRPV3 Channels.
PLoS ONE, 2014 , 9 (e99828).

40

Luo J et al. Thermally activated TRPV3 channels.
Curr Top Membr, 2014 , 74 (325-64).

41

Baez D et al. Gating of thermally activated channels.
Curr Top Membr, 2014 , 74 (51-87).

42

Doñate-Macian P et al. Dissecting domain-specific evolutionary pressure profiles of transient receptor potential vanilloid subfamily members 1 to 4.
PLoS ONE, 2014 , 9 (e110715).

43

Roper SD TRPs in taste and chemesthesis.
Handb Exp Pharmacol, 2014 , 223 (827-71).

44

Yang P et al. TRPV3.
Handb Exp Pharmacol, 2014 , 222 (273-91).

45

Zhai C et al. Identification of natural compound carnosol as a novel TRPA1 receptor agonist.
Molecules, 2014 , 19 (18733-46).

46

Duan X Ion Channels, Channelopathies, and Tooth Formation.
J. Dent. Res., 2013 Sep 27 , ().

47

Morgan PJ et al. Spontaneous calcium transients in human neural progenitor cells mediated by transient receptor potential channels.
Stem Cells Dev., 2013 Sep 15 , 22 (2477-86).

48

Brederson JD et al. Targeting TRP channels for pain relief.
Eur. J. Pharmacol., 2013 Sep 15 , 716 (61-76).

49

Kol S et al. Heterologous expression and purification of an active human TRPV3 ion channel.
FEBS J., 2013 Sep 13 , ().

50

Makarieva TN et al. Pulchranins B and C, new acyclic guanidine alkaloids from the Far-Eastern marine sponge Monanchora pulchra.
Nat Prod Commun, 2013 Sep , 8 (1229-32).

51

Selescu T et al. Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin.
Chem. Senses, 2013 Sep , 38 (563-75).

52

Reilly JM et al. Kv7/M-type potassium channels in rat skin keratinocytes.
Pflugers Arch., 2013 Sep , 465 (1371-81).

53

Liang CY et al. [Expression of transient receptor potential vanilloid 3 ion channel protein in human odontoblasts].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2013 Nov , 48 (679-82).

54

Sobhan U et al. Immunolocalization and distribution of functional temperature-sensitive TRP channels in salivary glands.
Cell Tissue Res., 2013 Nov , 354 (507-19).

55

Sherkheli MA et al. Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues.
Pak J Pharm Sci, 2013 May , 26 (431-8).

56

Nilius B et al. TRPV3: time to decipher a poorly understood family member !
J. Physiol. (Lond.), 2013 Jul 22 , ().

57

Nilius B et al. TRPV3: a 'more than skinny' channel.
Exp. Dermatol., 2013 Jul , 22 (447-52).

58

Schulze A et al. Apomorphine is a bimodal modulator of TRPA1 channels.
Mol. Pharmacol., 2013 Feb , 83 (542-51).

59

Joseph J et al. Carboxyl-terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin- and heat-induced desensitization.
J. Biol. Chem., 2013 Dec 13 , 288 (35690-702).

60

Carvacho I et al. TRPV3 Channels Mediate Strontium-Induced Mouse-Egg Activation.
Cell Rep, 2013 Dec 12 , 5 (1375-86).

61

Shi DJ et al. Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function.
Protein Cell, 2013 Dec , 4 (942-50).

62

Yamamoto-Kasai E et al. Impact of TRPV3 on the development of allergic dermatitis as a dendritic cell modulator.
Exp. Dermatol., 2013 Dec , 22 (820-4).

63

Shabir S et al. Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium.
Am. J. Physiol. Renal Physiol., 2013 Aug 1 , 305 (F396-406).

64

O'Mullane LM et al. Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium.
J. Urol., 2013 Aug , 190 (737-45).

65

Brown TE et al. Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice.
Hippocampus, 2013 Aug , 23 (662-71).

66

Kim SE et al. Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations.
PLoS ONE, 2013 , 8 (e59593).

67

Akazawa Y et al. Activation of TRPV4 strengthens the tight-junction barrier in human epidermal keratinocytes.
Skin Pharmacol Physiol, 2013 , 26 (15-21).

68

Danso-Abeam D et al. Olmsted syndrome: exploration of the immunological phenotype.
Orphanet J Rare Dis, 2013 , 8 (79).

69

Bishnoi M et al. Expression of multiple Transient Receptor Potential channel genes in murine 3T3-L1 cell lines and adipose tissue.
Pharmacol Rep, 2013 , 65 (751-5).

70

[Thermosensitive TRP channels gene expression in hypothalamus of normal rats and rats adapted to cold].
Ross Fiziol Zh Im I M Sechenova, 2012 Sep , 98 (1101-10).

71

Ferrer-Montiel A et al. Advances in modulating thermosensory TRP channels.
Expert Opin Ther Pat, 2012 Sep , 22 (999-1017).

72

Luo J et al. Tonic inhibition of TRPV3 by Mg2+ in mouse epidermal keratinocytes.
J. Invest. Dermatol., 2012 Sep , 132 (2158-65).

73

Jang Y et al. Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res., 2012 Oct , 35 (1823-30).

74

Ortar G et al. Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds.
Bioorg. Med. Chem. Lett., 2012 May 15 , 22 (3535-9).

75

Lin Z et al. Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome.
Am. J. Hum. Genet., 2012 Mar 9 , 90 (558-64).

76

Cao X et al. Intracellular proton-mediated activation of TRPV3 channels accounts for the exfoliation effect of α-hydroxyl acids on keratinocytes.
J. Biol. Chem., 2012 Jul 27 , 287 (25905-16).

77

Yoo HY et al. Role of thromboxane A₂-activated nonselective cation channels in hypoxic pulmonary vasoconstriction of rat.
Am. J. Physiol., Cell Physiol., 2012 Jan , 302 (C307-17).

78

Carreño O et al. SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.
Am. J. Med. Genet. B Neuropsychiatr. Genet., 2012 Jan , 159B (94-103).

79

Bang S et al. Nociceptive and proinflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation.
, 2012 Feb 2 , ().

80

De Petrocellis L et al. Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation.
Acta Physiol (Oxf), 2012 Feb , 204 (255-66).

81

Gifford JR et al. Changes in dermal interstitial ATP levels during local heating of human skin.
J. Physiol. (Lond.), 2012 Dec 15 , 590 (6403-11).

82

Chokshi R et al. 2-Aminoethyl diphenyl borinate (2-APB) inhibits TRPM7 channels through an intracellular acidification mechanism.
Channels (Austin), 2012 Aug 24 , 6 ().

83

Premkumar LS et al. TRP channels and analgesia.
Life Sci., 2012 Aug 14 , ().

84

Yamamoto-Kasai E et al. TRPV3 as a therapeutic target for itch.
J. Invest. Dermatol., 2012 Aug , 132 (2109-12).

85

Lai-Cheong JE et al. Recurrent heterozygous missense mutation, p.Gly573Ser, in the TRPV3 gene in an Indian boy with sporadic Olmsted syndrome.
Br. J. Dermatol., 2012 Aug , 167 (440-2).

86

Kida N et al. Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes.
Pflugers Arch., 2012 Apr , 463 (715-25).

87

Sherkheli MA et al. Supercooling Agent Icilin Blocks a Warmth-Sensing Ion Channel TRPV3.
ScientificWorldJournal, 2012 , 2012 (982725).

88

Miller M et al. Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
J. Biol. Chem., 2011 Sep 23 , 286 (33436-46).

89

Pan JP et al. Some subtypes of endocannabinoid/endovanilloid receptors mediate docosahexaenoic acid-induced enhanced spatial memory in rats.
Brain Res., 2011 Sep 15 , 1412 (18-27).

90

Baylie RL et al. TRPV channels and vascular function.
Acta Physiol (Oxf), 2011 Sep , 203 (99-116).

91

Wang S et al. C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.
J. Biol. Chem., 2011 Nov 25 , 286 (40601-7).

92

Liu B et al. Hysteresis of gating underlines sensitization of TRPV3 channels.
J. Gen. Physiol., 2011 Nov , 138 (509-20).

93

Borbíró I et al. Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth.
, 2011 May 19 , ().

94

Huang SM et al. TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation.
, 2011 May 17 , 7 (37).

95

Holzer P Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
, 2011 Mar 17 , ().

96

Doerner JF et al. Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2 hydrolysis.
J. Gen. Physiol., 2011 Mar , 137 (271-88).

97

Bang S et al. 17(R)-resolvin D1 specifically inhibits TRPV3 leading to peripheral antinociception.
, 2011 Jun 30 , ().

98

Eid SR Therapeutic Targeting of TRP Channels - The TR(i)P to Pain Relief.
, 2011 Jun 14 , ().

99

Reilly RM et al. Analgesic Potential of TRPV3 Antagonists.
, 2011 Jun 14 , ().

100

Vincent F et al. TRPV4 Agonists and Antagonists.
, 2011 Jun 14 , ().

101

Vay L et al. The thermo-TRP ion channel family: properties and therapeutic implications.
, 2011 Jul 28 , ().

102

Mergler S et al. Thermosensitive transient receptor potential channels in human corneal epithelial cells.
J. Cell. Physiol., 2011 Jul , 226 (1828-42).

103

Bang S et al. Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
, 2011 Feb 23 , ().

104

Earley S Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels.
J. Cardiovasc. Pharmacol., 2011 Feb , 57 (148-53).

105

Sulk M et al. Distribution and Expression of Non-Neuronal Transient Receptor Potential (TRPV) Ion Channels in Rosacea.
, 2011 Dec 22 , ().

106

Cheng W et al. Heteromeric heat-sensitive TRP channels exhibit distinct temperature and chemical response.
, 2011 Dec 19 , ().

107

Saito S et al. Evolution of vertebrate transient receptor potential vanilloid 3 channels: opposite temperature sensitivity between mammals and western clawed frogs.
PLoS Genet., 2011 Apr , 7 (e1002041).

108

Miyamoto T et al. TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin.
Nat Commun, 2011 , 2 (369).

109

Wetsel WC Sensing hot and cold with TRP channels.
Int J Hyperthermia, 2011 , 27 (388-98).

110

Chung MK et al. Role of TRP channels in pain sensation.
Adv. Exp. Med. Biol., 2011 , 704 (615-36).

111

Hu J et al. Infrared heat treatment reduces food intake and modifies expressions of TRPV3-POMC in the dorsal medulla of obesity prone rats.
Int J Hyperthermia, 2011 , 27 (708-16).