ClC2

Description: chloride channel 2
Gene: Clcn2
Alias: clc2, clc-2, clcn2

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	1181	3	15420
Mouse	12724	16	15311
Rat	29232	11	13916

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_004366.6	3244
Mouse	NM_009900.2	3670
Rat	NM_017137.2	3153

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	P51788	898
Mouse	Q9R0A1	908
Rat	P35525	907

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NM_001171088.3

3112

NP_001164559.1

854

transcript variant 3

isoform 3

NM_001171087.3

3193

NP_001164558.1

881

transcript variant 2

isoform 2

NM_001171089.3

3157

NP_001164560.1

869

transcript variant 4

isoform 4

NM_004366.6

3244

NP_004357.3

898

transcript variant 1

isoform 1

Predicted

XM_006713489.2

3139

XP_006713552.1

863

transcript variant X1

isoform X1

XM_011512401.2

6968

XP_011510703.1

835

transcript variant X2

isoform X2

XM_047447419.1

1904

XP_047303375.1

529

transcript variant X3

isoform X3

XM_054345165.1

3139

XP_054201140.1

863

transcript variant X1

isoform X1

XM_054345166.1

6995

XP_054201141.1

835

transcript variant X2

isoform X2

XM_054345167.1

1904

XP_054201142.1

529

transcript variant X3

isoform X3

Known

NM_009900.2

3670

NP_034030.2

908

isoform 1

NM_001416770.1

2806

NP_001403699.1

828

isoform 4

NM_001416768.1

3144

NP_001403697.1

915

isoform 2

NM_001416769.1

3063

NP_001403698.1

888

isoform 3

Predicted

XR_384520.4

4855

transcript variant X10

XR_003951749.2

3383

transcript variant X9

XR_004939155.1

3593

transcript variant X8

XR_001781785.3

3427

transcript variant X5

XR_004939154.1

3637

transcript variant X4

XR_003951748.2

3641

transcript variant X7

XR_003951747.2

3851

transcript variant X6

XM_006521749.5

4692

XP_006521812.1

642

transcript variant X2

isoform X2

XM_030248952.2

3683

XP_030104812.1

642

transcript variant X3

isoform X2

XM_017316862.3

3646

XP_017172351.1

915

transcript variant X1

isoform X1

Known

NM_017137.2

3153

NP_058833.1

907

Predicted

XR_595157.3

3601

transcript variant X7

XR_595158.3

3541

transcript variant X8

XR_358402.4

3106

transcript variant X4

XR_595156.3

3073

transcript variant X5

XR_005491015.1

2095

transcript variant X15

XM_039088237.1

3616

XP_038944165.1

848

transcript variant X2

isoform X2

XM_006248563.4

3533

XP_006248625.1

887

transcript variant X1

isoform X1

XM_039088238.1

3436

XP_038944166.1

801

transcript variant X3

isoform X3

XM_039088239.1

3304

XP_038944167.1

780

transcript variant X6

isoform X4

XM_039088243.1

2308

XP_038944171.1

531

transcript variant X12

isoform X7

XM_039088240.1

2413

XP_038944168.1

643

transcript variant X9

isoform X5

XM_039088241.1

2410

XP_038944169.1

643

transcript variant X10

isoform X5

XM_039088242.1

2122

XP_038944170.1

553

transcript variant X11

isoform X6

XM_039088245.1

1880

XP_038944173.1

476

transcript variant X14

isoform X9

XM_039088244.1

1908

XP_038944172.1

478

transcript variant X13

isoform X8

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Post-Translational Modifications

PTM

Position

Type

Modified residue

N-acetylalanine

Modified residue

Phosphothreonine

Modified residue

712

Phosphoserine

Modified residue

758

Phosphoserine

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Structure

ClC2 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	4745.25	source
Mouse	6222.67	source
Rat	6027.96	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/104/ , accessed on 2025 Nov 03

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