TRPC6

1

Wang Q et al. Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.
Am. J. Physiol., Cell Physiol., 2016 May 4 , (ajpcell.00092.2016).

2

Sawamura S et al. Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.
Mol. Pharmacol., 2016 Mar , 89 (348-63).

3

Yao XM et al. Astragaloside IV prevents high glucose-induced podocyte apoptosis via downregulation of TRPC6.
Mol Med Rep, 2016 Jun , 13 (5149-56).

4

Sexton JE et al. The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.
Neurosci. Lett., 2016 Jan 1 , 610 (36-42).

5

Urban N et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
Mol. Pharmacol., 2016 Jan , 89 (197-213).

6

Riehle M et al. TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.
J. Am. Soc. Nephrol., 2016 Feb 18 , ().

7

Meijer L et al. Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.
J Innate Immun, 2016 , 8 (330-49).

8

Wu X et al. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 , 11 (e0155577).

9

Liu Z et al. Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes.
Cell Calcium, 2015 Sep 3 , ().

10

Ambrus L et al. Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes.
J. Cell. Mol. Med., 2015 Sep 25 , ().

11

Weber EW et al. TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response.
J. Exp. Med., 2015 Sep 21 , ().

12

Li S et al. Crucial role of TRPC6 in maintaining the stability of HIF-1α in glioma cells under hypoxia.
J. Cell. Sci., 2015 Sep 1 , 128 (3317-29).

13

Ilatovskaya DV et al. TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases.
Am. J. Physiol. Renal Physiol., 2015 Sep 1 , 309 (F393-7).

14

Bullich G et al. Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity.
Eur. J. Hum. Genet., 2015 Sep , 23 (1192-9).

15

Szabó T et al. Regulation of TRPC6 ion channels in podocytes - Implications for focal segmental glomerulosclerosis and acquired forms of proteinuric diseases.
Acta Physiol Hung, 2015 Sep , 102 (241-51).

16

Smith KA et al. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
Am. J. Respir. Cell Mol. Biol., 2015 Sep , 53 (355-67).

17

Sozucan Y et al. TRP genes family expression in colorectal cancer.
Exp. Oncol., 2015 Sep , 37 (208-12).

18

Lopez E et al. FKBP25 and FKBP38 regulate non-capacitative calcium entry through TRPC6.
Biochim. Biophys. Acta, 2015 Oct , 1853 (2684-96).

19

Kim EY et al. Syndecan-4 ectodomain evokes mobilization of podocyte TRPC6 channels and their associated pathways: An essential role for integrin signaling.
Biochim. Biophys. Acta, 2015 Oct , 1853 (2610-20).

20

Riazanski V et al. TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Proc. Natl. Acad. Sci. U.S.A., 2015 Nov 24 , 112 (E6486-95).

21

Wu J et al. MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes.
J. Clin. Invest., 2015 Nov 2 , 125 (4091-106).

22

Ramirez GA et al. TRPC6 gene variants and neuropsychiatric lupus.
J. Neuroimmunol., 2015 Nov 15 , 288 (21-4).

23

Lopez E et al. Relationship between calcium mobilization and platelet α- and δ-granule secretion. A role for TRPC6 in thrombin-evoked δ-granule exocytosis.
Arch. Biochem. Biophys., 2015 Nov 1 , 585 (75-81).

24

Joshi BB et al. In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome.
Gene, 2015 Nov 1 , 572 (8-16).

25

Liu Y et al. The change of spatial cognition ability in depression rat model and the possible association with down-regulated protein expression of TRPC6.
Behav. Brain Res., 2015 Nov 1 , 294 (186-93).

26

Chauvet S et al. The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels.
Biochim. Biophys. Acta, 2015 Nov , 1853 (2957-65).

27

Zhao B et al. The role of TRPC6 in oxidative stress-induced podocyte ischemic injury.
Biochem. Biophys. Res. Commun., 2015 May 29 , 461 (413-20).

28

Lin XH et al. Upregulation of TRPC1/6 may be involved in arterial remodeling in rat.
J. Surg. Res., 2015 May 1 , 195 (334-43).

29

Wang L et al. Gq signaling causes glomerular injury by activating TRPC6.
J. Clin. Invest., 2015 May , 125 (1913-26).

30

Lu XY et al. Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.
Biochim. Biophys. Acta, 2015 May , 1853 (965-74).

31

Tabeling C et al. CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
Proc. Natl. Acad. Sci. U.S.A., 2015 Mar 31 , 112 (E1614-23).

32

De Clercq K et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle.
Hum. Reprod., 2015 Mar 27 , ().

33

Pandit MM et al. Flow regulation of endothelin-1 production in the inner medullary collecting duct.
Am. J. Physiol. Renal Physiol., 2015 Mar 15 , 308 (F541-52).

34

Wu QY et al. Activation of calcium-sensing receptor increases TRPC3/6 expression in T lymphocyte in sepsis.
Mol. Immunol., 2015 Mar , 64 (18-25).

35

Wang Y et al. Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry.
J. Mol. Med., 2015 Mar , 93 (327-42).

36

Kurahara LH et al. Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease.
Inflamm. Bowel Dis., 2015 Mar , 21 (496-506).

37

Yang K et al. Noggin inhibits hypoxia-induced proliferation by targeting store-operated calcium entry and transient receptor potential cation channels.
Am. J. Physiol., Cell Physiol., 2015 Jun 1 , 308 (C869-78).

38

Kalwa H et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes.
J. Cell. Physiol., 2015 Jun , 230 (1389-99).

39

Nakamura T et al. Prevention of PKG1α oxidation augments cardioprotection in the stressed heart.
J. Clin. Invest., 2015 Jun , 125 (2468-72).

40

Shengyou Y et al. Influence of tacrolimus on podocyte injury inducted by angiotensin II.
J Renin Angiotensin Aldosterone Syst, 2015 Jun , 16 (260-6).

41

Forst AL et al. Podocyte Purinergic P2X4 Channels Are Mechanotransducers That Mediate Cytoskeletal Disorganization.
J. Am. Soc. Nephrol., 2015 Jul 9 , ().

42

Abkhezr M et al. Pleiotropic signaling evoked by tumor necrosis factor in podocytes.
Am. J. Physiol. Renal Physiol., 2015 Jul 15 , 309 (F98-108).

43

Wang J et al. Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs.
Cardiovasc. Res., 2015 Jul 1 , 107 (108-18).

44

Maier T et al. Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels.
Br. J. Pharmacol., 2015 Jul , 172 (3650-60).

45

Vachel L et al. The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity.
Cell Calcium, 2015 Jan , 57 (38-48).

46

Zhang X et al. The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats.
Mol. Cell. Biochem., 2015 Jan , 399 (155-65).

47

Veit F et al. Hypoxia-dependent reactive oxygen species signaling in the pulmonary circulation: focus on ion channels.
Antioxid. Redox Signal., 2015 Feb 20 , 22 (537-52).

48

Pfister S et al. Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis.
J. Comp. Neurol., 2015 Feb 15 , 523 (406-30).

49

Alptekin M et al. Gene expressions of TRP channels in glioblastoma multiforme and relation with survival.
Tumour Biol., 2015 Dec , 36 (9209-13).

50

Iyer SC et al. Receptor channel TRPC6 orchestrate the activation of human hepatic stellate cell under hypoxia condition.
Exp. Cell Res., 2015 Aug 1 , 336 (66-75).

51

Zou ZQ et al. Down-regulation of SENCR promotes smooth muscle cells proliferation and migration in db/db mice through up-regulation of FoxO1 and TRPC6.
Biomed. Pharmacother., 2015 Aug , 74 (35-41).

52

Zúñiga-García V et al. Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.
Dig. Dis. Sci., 2015 Apr 5 , ().

53

Fernandez RA et al. Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.
Am. J. Physiol., Cell Physiol., 2015 Apr 15 , 308 (C581-93).

54

Selli C et al. Silencing of TRPC1 regulates store-operated calcium entry and proliferation in Huh7 hepatocellular carcinoma cells.
Biomed. Pharmacother., 2015 Apr , 71 (194-200).

55

Tabur S et al. Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.
Eur Rev Med Pharmacol Sci, 2015 Apr , 19 (1388-97).

56

Vemana HP et al. A critical role for the transient receptor potential channel type 6 in human platelet activation.
PLoS ONE, 2015 , 10 (e0125764).

57

Choi HJ et al. Astrocytes in the optic nerve head express putative mechanosensitive channels.
Mol. Vis., 2015 , 21 (749-66).

58

Kong F et al. Alpha1-Adrenergic Receptor Activation Stimulates Calcium Entry and Proliferation via TRPC6 Channels in Cultured Human Mesangial Cells.
Cell. Physiol. Biochem., 2015 , 36 (1928-38).

59

Chen YM et al. Focal segmental glomerulosclerosis: molecular genetics and targeted therapies.
BMC Nephrol, 2015 , 16 (101).

60

Peng G et al. Chronic Hypoxia Increases Intracellular Ca(2+) Concentration via Enhanced Ca(2+) Entry Through Receptor-Operated Ca(2+) Channels in Pulmonary Venous Smooth Muscle Cells.
Circ. J., 2015 , 79 (2058-68).

61

Zhang Y et al. MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis.
Sci Rep, 2015 , 5 (9401).

62

Pousada G et al. Molecular and clinical analysis of TRPC6 and AGTR1 genes in patients with pulmonary arterial hypertension.
Orphanet J Rare Dis, 2015 , 10 (1).

63

Berna-Erro A et al. The canonical transient receptor potential 6 (TRPC6) channel is sensitive to extracellular pH in mouse platelets.
Blood Cells Mol. Dis., 2014 Feb-Mar , 52 (108-15).

64

Zeng C et al. Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy.
Mol. Neurobiol., 2014 Sep 12 , ().

65

Hill-Eubanks DC et al. Vascular TRP channels: performing under pressure and going with the flow.
Physiology (Bethesda), 2014 Sep , 29 (343-60).

66

Takada H et al. Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes.
J. Cell. Sci., 2014 Oct 1 , 127 (4159-71).

67

Albarrán L et al. STIM1 regulates TRPC6 heteromultimerization and subcellular location.
Biochem. J., 2014 Nov 1 , 463 (373-81).

68

Richter JM et al. Clemizole hydrochloride is a novel and potent inhibitor of transient receptor potential channel TRPC5.
Mol. Pharmacol., 2014 Nov , 86 (514-21).

69

Schleifenbaum J et al. Stretch-Activation of Angiotensin II Type 1a Receptors Contributes to the Myogenic Response of Mouse Mesenteric and Renal Arteries.
Circ. Res., 2014 May 16 , ().

70

Rosenbaum MA et al. Hypercholesterolemia inhibits re-endothelialization of arterial injuries by TRPC channel activation.
J. Vasc. Surg., 2014 May 10 , ().

71

Roshanravan H et al. ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species.
Am. J. Physiol. Renal Physiol., 2014 May 1 , 306 (F1088-97).

72

Wilson C et al. A mutation in TRPC6 channels abolishes their activation by hypoosmotic stretch but does not affect activation by diacylglycerol or G protein signaling cascades.
Am. J. Physiol. Renal Physiol., 2014 May 1 , 306 (F1018-25).

73

Song X et al. Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression.
Biochim. Biophys. Acta, 2014 May , 1843 (894-901).

74

Lee KP et al. Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1).
J. Biol. Chem., 2014 Mar 7 , 289 (6372-82).

75

Ilatovskaya DV et al. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.
Kidney Int., 2014 Mar 19 , ().

76

Tran VT et al. Mechanotransduction channels of the trabecular meshwork.
Curr. Eye Res., 2014 Mar , 39 (291-303).

77

Lei L et al. The role of mechanical tension on lipid raft dependent PDGF-induced TRPC6 activation.
Biomaterials, 2014 Mar , 35 (2868-77).

78

Hall G et al. Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.
Am. J. Physiol. Renal Physiol., 2014 Jun 15 , 306 (F1442-50).

79

Sonneveld R et al. Glucose specifically regulates TRPC6 expression in the podocyte in an AngII-dependent manner.
Am. J. Pathol., 2014 Jun , 184 (1715-26).

80

McPate M et al. The Development of Automated Patch Clamp Assays for Canonical Transient Receptor Potential Channels TRPC3, 6, and 7.
Assay Drug Dev Technol, 2014 Jun , 12 (282-92).

81

Thilo F et al. High glucose modifies transient receptor potential canonical type 6 channels via increased oxidative stress and syndecan-4 in human podocytes.
Biochem. Biophys. Res. Commun., 2014 Jul 18 , 450 (312-7).

82

Sung HH et al. Increased expression of TRPC4 channels associated with erectile dysfunction in diabetes.
Andrology, 2014 Jul , 2 (550-8).

83

Ding Y et al. The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein.
J. Pharmacol. Exp. Ther., 2014 Jul , 350 (14-21).

84

Sun L et al. Astragaloside IV prevents damage to human mesangial cells through the inhibition of the NADPH oxidase/ROS/Akt/NF‑κB pathway under high glucose conditions.
Int. J. Mol. Med., 2014 Jul , 34 (167-76).

85

Chevallet M et al. Functional consequences of the over-expression of TRPC6 channels in HEK cells: impact on the homeostasis of zinc.
Metallomics, 2014 Jul , 6 (1269-76).

86

Seo K et al. Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jan 28 , 111 (1551-6).

87

Su B et al. Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission.
J. Biol. Chem., 2014 Jan 17 , 289 (1213-26).

88

Zhang LW et al. [Recent advances in the research on mechanisms underlying podocyte-specific gene mutation-related steroid-resistant nephrotic syndrome].
Zhongguo Dang Dai Er Ke Za Zhi, 2014 Jan , 16 (99- following 102).

89

Jiang Y et al. Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stages.
Cell Tissue Res., 2014 Jan , 355 (201-12).

90

Yao C et al. Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
Mol Med Rep, 2014 Jan , 9 (69-76).

91

Wang D et al. Effects of TRPC6 on invasibility of low-differentiated prostate cancer cells.
Asian Pac J Trop Med, 2014 Jan , 7 (44-7).

92

Xia Y et al. Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions.
Hypertension, 2014 Jan , 63 (173-80).

93

Seo K et al. Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation.
Circ. Res., 2014 Feb 28 , 114 (823-32).

94

Wang J et al. Effects of chronic exposure to cigarette smoke on canonical transient receptor potential expression in rat pulmonary arterial smooth muscle.
Am. J. Physiol., Cell Physiol., 2014 Feb 15 , 306 (C364-73).

95

Itsuki K et al. PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.
J. Gen. Physiol., 2014 Feb , 143 (183-201).

96

Saliba Y et al. Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis.
J. Am. Soc. Nephrol., 2014 Dec 5 , ().

97

Ichikawa J et al. TRPC6 regulates cell cycle progression by modulating membrane potential in bone marrow stromal cells.
Br. J. Pharmacol., 2014 Dec , 171 (5280-94).

98

Kwon M et al. Single-cell RT-PCR and immunocytochemical detection of mechanosensitive transient receptor potential channels in acutely isolated rat odontoblasts.
Arch. Oral Biol., 2014 Dec , 59 (1266-71).

99

Zhang J et al. IL-17A contributes to brain ischemia reperfusion injury through calpain-TRPC6 pathway in mice.
Neuroscience, 2014 Aug 22 , 274 (419-28).

100

Song S et al. Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.
Am. J. Physiol., Cell Physiol., 2014 Aug 15 , 307 (C373-83).

101

Abkhezr M et al. Angiotensin II and canonical transient receptor potential-6 activation stimulate release of a signal transducer and activator of transcription 3-activating factor from mouse podocytes.
Mol. Pharmacol., 2014 Aug , 86 (150-8).

102

Schurek EM et al. A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.
J. Biol. Chem., 2014 Apr 18 , 289 (11262-71).

103

Chen W et al. Orai1-induced store-operated Ca(2+) entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets.
J. Thromb. Haemost., 2014 Apr , 12 (528-39).

104

Albarrán L et al. TRPC6 participates in the regulation of cytosolic basal calcium concentration in murine resting platelets.
Biochim. Biophys. Acta, 2014 Apr , 1843 (789-96).

105

Anderson M et al. Angiotensin II activation of TRPC6 channels in rat podocytes requires generation of reactive oxygen species.
J. Cell. Physiol., 2014 Apr , 229 (434-42).

106

Zhang X et al. Transient receptor potential canonical 7: a diacylglycerol-activated non-selective cation channel.
Handb Exp Pharmacol, 2014 , 222 (189-204).

107

Montecinos-Oliva C et al. Effects of tetrahydrohyperforin in mouse hippocampal slices: neuroprotection, long-term potentiation and TRPC channels.
Curr. Med. Chem., 2014 , 21 (3494-506).

108

Ong HL et al. Physiological functions and regulation of TRPC channels.
Handb Exp Pharmacol, 2014 , 223 (1005-34).

109

Dietrich A et al. TRPC6: physiological function and pathophysiological relevance.
Handb Exp Pharmacol, 2014 , 222 (157-88).

110

Hardie RC Photosensitive TRPs.
Handb Exp Pharmacol, 2014 , 223 (795-826).

111

Chigurupati S et al. Functional and structural analysis of mice TRPC6 with human analogue through homology modelling.
Int J Bioinform Res Appl, 2014 , 10 (206-16).

112

Gonzales AL et al. A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.
Sci Signal, 2014 , 7 (ra49).

113

Meng K et al. Calcium sensing receptor modulates extracellular calcium entry and proliferation via TRPC3/6 channels in cultured human mesangial cells.
PLoS ONE, 2014 , 9 (e98777).

114

Zufall F TRPs in olfaction.
Handb Exp Pharmacol, 2014 , 223 (917-33).

115

Shimizu S et al. TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters).
Handb Exp Pharmacol, 2014 , 223 (767-94).

116

Ding F et al. Mammalian target of rapamycin complex 2 signaling pathway regulates transient receptor potential cation channel 6 in podocytes.
PLoS ONE, 2014 , 9 (e112972).

117

Sell TS et al. Protonophore properties of hyperforin are essential for its pharmacological activity.
Sci Rep, 2014 , 4 (7500).

118

Hofstra JM et al. TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy.
PLoS ONE, 2014 , 9 (e102065).

119

Xu L et al. Chronic hypoxia increases TRPC6 expression and basal intracellular Ca2+ concentration in rat distal pulmonary venous smooth muscle.
PLoS ONE, 2014 , 9 (e112007).

120

Zanini D et al. TRPs in Hearing.
Handb Exp Pharmacol, 2014 , 223 (899-916).

121

Thodeti CK et al. A TRP to cardiac fibroblast differentiation.
Channels (Austin), 2013 May-Jun , 7 (211-4).

122

Washburn DG et al. The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore.
Bioorg. Med. Chem. Lett., 2013 Sep 1 , 23 (4979-84).

123

Han H et al. Novel role of NOD2 in mediating Ca2+ signaling: evidence from NOD2-regulated podocyte TRPC6 channels in hyperhomocysteinemia.
Hypertension, 2013 Sep , 62 (506-11).

124

Chen W et al. Atrial natriuretic peptide-mediated inhibition of microcirculatory endothelial Ca2+ and permeability response to histamine involves cGMP-dependent protein kinase I and TRPC6 channels.
Arterioscler. Thromb. Vasc. Biol., 2013 Sep , 33 (2121-9).

125

Liu X et al. Recombinant human erythropoietin pretreatment alleviates renal glomerular injury induced by cardiopulmonary bypass by reducing transient receptor potential channel 6-nuclear factor of activated T-cells pathway activation.
J. Thorac. Cardiovasc. Surg., 2013 Sep , 146 (681-7).

126

Ikeda K et al. Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na+/Ca2+ exchanger on cell proliferation in human cardiac fibroblasts: effects of transforming growth factor β1.
Cell Calcium, 2013 Sep , 54 (213-25).

127

Hayes HL et al. Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
Mol. Cell. Biol., 2013 Oct , 33 (4017-29).

128

Kim EY et al. NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex.
Am. J. Physiol., Cell Physiol., 2013 Nov 1 , 305 (C960-71).

129

Loga F et al. The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone.
Cardiovasc. Res., 2013 Nov 1 , 100 (280-7).

130

Kuang XY et al. 254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children.
Pediatr. Res., 2013 Nov , 74 (511-6).

131

Toth P et al. Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
J. Cereb. Blood Flow Metab., 2013 Nov , 33 (1732-42).

132

Heiser JH et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling.
J. Neurochem., 2013 Nov , 127 (303-13).

133

Yang H et al. High glucose-induced apoptosis in cultured podocytes involves TRPC6-dependent calcium entry via the RhoA/ROCK pathway.
Biochem. Biophys. Res. Commun., 2013 May 3 , 434 (394-400).

134

Wang Y et al. Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells.
J. Biol. Chem., 2013 May 3 , 288 (12852-65).

135

Zhang Y et al. Bone morphogenetic protein 2 decreases TRPC expression, store-operated Ca(2+) entry, and basal [Ca(2+)]i in rat distal pulmonary arterial smooth muscle cells.
Am. J. Physiol., Cell Physiol., 2013 May 1 , 304 (C833-43).

136

Zhang L et al. Deferoxamine attenuates iron-induced long-term neurotoxicity in rats with traumatic brain injury.
Neurol. Sci., 2013 May , 34 (639-45).

137

Qiu G et al. AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration.
Clin. Exp. Med., 2013 Mar 5 , ().

138

Nagy GA et al. DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation.
Hippocampus, 2013 Mar , 23 (221-32).

139

Eltit JM et al. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia.
FASEB J., 2013 Mar , 27 (991-1000).

140

Harper MT et al. Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.
Sci Signal, 2013 Jun 25 , 6 (ra50).

141

Mahaut-Smith MP A role for platelet TRPC channels in the Ca2+ response that induces procoagulant activity.
Sci Signal, 2013 Jun 25 , 6 (pe23).

142

Chiluiza D et al. Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).
J. Biol. Chem., 2013 Jun 21 , 288 (18407-20).

143

Bon RS et al. In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels - mirage or pot of gold?
Br. J. Pharmacol., 2013 Jun 14 , ().

144

Shi J et al. Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.
J. Physiol. (Lond.), 2013 Jun 1 , 591 (2851-66).

145

Linde CI et al. Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca(2+) entry pathway.
Am. J. Physiol., Cell Physiol., 2013 Jun 1 , 304 (C1098-104).

146

Lindemann O et al. TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils.
J. Immunol., 2013 Jun 1 , 190 (5496-505).

147

Shen H et al. TRPC6 inhibited NMDA current in cultured hippocampal neurons.
Neuromolecular Med., 2013 Jun , 15 (389-95).

148

Liu BC et al. High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species.
Biochim. Biophys. Acta, 2013 Jun , 1833 (1434-42).

149

Sah R et al. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization.
Circulation, 2013 Jul 9 , 128 (101-14).

150

Kiso H et al. Sildenafil prevents the up-regulation of transient receptor potential canonical channels in the development of cardiomyocyte hypertrophy.
Biochem. Biophys. Res. Commun., 2013 Jul 5 , 436 (514-8).

151

Narayanan D et al. Smooth Muscle Cell Transient Receptor Potential Polycystin (TRPP)2 Channels Contribute To The Myogenic Response In Cerebral Arteries.
J. Physiol. (Lond.), 2013 Jul 15 , ().

152

Dasari S et al. Do canonical transient receptor potential channels mediate cholinergic excitation of cortical pyramidal neurons?
Neuroreport, 2013 Jul 10 , 24 (550-4).

153

Lin Y et al. Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways.
J. Mol. Neurosci., 2013 Jul , 50 (504-13).

154

Lipska BS et al. Genetic screening in adolescents with steroid-resistant nephrotic syndrome.
Kidney Int., 2013 Jul , 84 (206-13).

155

Hofstra JM et al. New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.
Nephrol. Dial. Transplant., 2013 Jan 4 , ().

156

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