TRPM4

1

Wang Q et al. Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries.
Am. J. Physiol., Cell Physiol., 2016 May 4 , (ajpcell.00092.2016).

2

Daumy X et al. Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.
Int. J. Cardiol., 2016 Mar 15 , 207 (349-58).

3

Leitner MG et al. Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122.
Br. J. Pharmacol., 2016 Jun 21 , ().

4

Constantine M et al. Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer.
Sci Rep, 2016 , 6 (19352).

5

Kurland DB et al. The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.
J Neuroinflammation, 2016 , 13 (130).

6

Cheng H et al. Expression and functionality of transient receptor potential melastatin 4 (TRPM4)-like channels during development of the zebrafish.
Comp. Biochem. Physiol. C Toxicol. Pharmacol., 2015 Sep 30 , ().

7

Sozucan Y et al. TRP genes family expression in colorectal cancer.
Exp. Oncol., 2015 Sep , 37 (208-12).

8

Flannery RJ et al. A TRPM4-dependent current in murine renal primary cilia.
Am. J. Physiol. Renal Physiol., 2015 Oct 15 , 309 (F697-707).

9

Martínez-Valverde T et al. Sulfonylurea Receptor 1 in Humans with Post-Traumatic Brain Contusions.
J. Neurotrauma, 2015 Oct 1 , 32 (1478-87).

10

Bousova K et al. PIP2 and PIP3 interact with N-terminus region of TRPM4 channel.
Biophys. Chem., 2015 Oct , 205 (24-32).

11

Echeverria C et al. Suppression of transient receptor potential melastatin 4 expression promotes conversion of endothelial cells into fibroblasts via transforming growth factor/activin receptor-like kinase 5 pathway.
J. Hypertens., 2015 May , 33 (981-92).

12

Lee JY et al. 17β-estradiol inhibits MMP-9 and SUR1/TrpM4 expression and activation and thereby attenuates BSCB disruption/hemorrhage after spinal cord injury in male rats.
Endocrinology, 2015 May , 156 (1838-50).

13

De Clercq K et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle.
Hum. Reprod., 2015 Mar 27 , ().

14

Jacobs G et al. Enhanced β-adrenergic cardiac reserve in Trpm4-/- mice with ischaemic heart failure.
Cardiovasc. Res., 2015 Mar 1 , 105 (330-9).

15

Kecskés M et al. The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy.
Basic Res. Cardiol., 2015 Jul , 110 (43).

16

Burris SK et al. 9-phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels.
Br. J. Pharmacol., 2015 Jan 9 , ().

17

Baruteau AE et al. Inherited progressive cardiac conduction disorders.
Curr. Opin. Cardiol., 2015 Jan , 30 (33-9).

18

Cho CH et al. Physiological functions of the TRPM4 channels via protein interactions.
BMB Rep, 2015 Jan , 48 (1-5).

19

Garland CJ et al. TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery.
Br. J. Pharmacol., 2015 Feb , 172 (1114-23).

20

Menigoz A et al. TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons.
Pflugers Arch., 2015 Dec 3 , ().

21

Shigeto M et al. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
J. Clin. Invest., 2015 Dec , 125 (4714-28).

22

Mehta RI et al. Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.
J. Neuropathol. Exp. Neurol., 2015 Aug , 74 (835-49).

23

Cerda O et al. Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca²⁺-activated non-selective cation channel TRPM4.
Pflugers Arch., 2015 Aug , 467 (1723-32).

24

Isman E et al. Effects of laser irradiation at different wavelengths (660, 810, 980, and 1064 nm) on transient receptor potential melastatin channels in an animal model of wound healing.
Lasers Med Sci, 2015 Apr 12 , ().

25

Caffes N et al. Glibenclamide for the treatment of ischemic and hemorrhagic stroke.
Int J Mol Sci, 2015 , 16 (4973-84).

26

Makar TK et al. Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis.
J Neuroinflammation, 2015 , 12 (210).

27

Choi HJ et al. Astrocytes in the optic nerve head express putative mechanosensitive channels.
Mol. Vis., 2015 , 21 (749-66).

28

Cáceres M et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility.
PLoS ONE, 2015 , 10 (e0130540).

29

Piao H et al. Transient receptor potential melastatin-4 is involved in hypoxia-reoxygenation injury in the cardiomyocytes.
PLoS ONE, 2015 , 10 (e0121703).

30

Dusmez D et al. Effect of verapamil and lidocaine on TRPM and NaV1.9 gene expressions in renal ischemia-reperfusion.
Transplant. Proc., 2014 Jan-Feb , 46 (33-9).

31

Hill-Eubanks DC et al. Vascular TRP channels: performing under pressure and going with the flow.
Physiology (Bethesda), 2014 Sep , 29 (343-60).

32

Tran TD et al. Histamine-induced Ca²⁺ signalling is mediated by TRPM4 channels in human adipose-derived stem cells.
Biochem. J., 2014 Oct 1 , 463 (123-34).

33

Li Y et al. TRPM4 channels couple purinergic receptor mechanoactivation and myogenic tone development in cerebral parenchymal arterioles.
J. Cereb. Blood Flow Metab., 2014 Oct , 34 (1706-14).

34

Kecskes M et al. Retraction of: abstract P134, Increased beta-adrenergic inotropy in ventricular myocardium from Trpm4 knockout mice.
Cardiovasc. Res., 2014 Nov 1 , 104 (382).

35

Sakuraba M et al. Spatiotemporal expression of TRPM4 in the mouse cochlea.
J. Neurosci. Res., 2014 May 20 , ().

36

Demir T et al. Evaluation of TRPM (transient receptor potential melastatin) genes expressions in myocardial ischemia and reperfusion.
Mol. Biol. Rep., 2014 May , 41 (2845-9).

37

Loh KP et al. TRPM4 inhibition promotes angiogenesis after ischemic stroke.
Pflugers Arch., 2014 Mar , 466 (563-76).

38

Clémençon B et al. Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes.
Protein Expr. Purif., 2014 Mar , 95 (169-76).

39

Uhl S et al. Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice.
J. Mol. Cell. Cardiol., 2014 Jun 24 , ().

40

Mathar I et al. Increased β-Adrenergic Inotropy in Ventricular Myocardium From Trpm4-/- Mice.
Circ. Res., 2014 Jan 17 , 114 (283-94).

41

Guinamard R et al. The TRPM4 channel inhibitor 9-phenanthrol.
Br. J. Pharmacol., 2014 Jan 16 , ().

42

Khanna A et al. Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans.
Neurosurg Focus, 2014 Jan , 36 (E11).

43

Sarmiento D et al. Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel.
Microvasc. Res., 2014 Feb 9 , ().

44

Yamaguchi S et al. Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity.
J. Biol. Chem., 2014 Dec 19 , 289 (35265-82).

45

Lee JY et al. Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury.
Biochim. Biophys. Acta, 2014 Dec , 1842 (2403-12).

46

Kruse M et al. TRPM4 channels in the cardiovascular system.
Curr Opin Pharmacol, 2014 Apr , 15 (68-73).

47

Ghosh D et al. Distinct modes of perimembrane TRP channel turnover revealed by TIR-FRAP.
Sci Rep, 2014 , 4 (7111).

48

Syam N et al. Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects.
Front Cell Neurosci, 2014 , 8 (52).

49

Mathar I et al. TRPM4.
Handb Exp Pharmacol, 2014 , 222 (461-87).

50

Zufall F TRPs in olfaction.
Handb Exp Pharmacol, 2014 , 223 (917-33).

51

Lei YT et al. Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons.
Front Cell Neurosci, 2014 , 8 (267).

52

Gonzales AL et al. A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.
Sci Signal, 2014 , 7 (ra49).

53

Guinamard R et al. Current recordings at the single channel level in adult mammalian isolated cardiomyocytes.
Methods Mol. Biol., 2014 , 1183 (291-307).

54

Cho CH et al. Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death.
Mol Brain, 2014 , 7 (52).

55

Demion M et al. Trpm4 gene invalidation leads to cardiac hypertrophy and electrophysiological alterations.
PLoS ONE, 2014 , 9 (e115256).

56

Parajuli SP et al. Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol.
Channels (Austin), 2013 Nov-Dec , 7 (537-40).

57

Earley S TRPM4 channels in smooth muscle function.
Pflugers Arch., 2013 Sep , 465 (1223-31).

58

Saul S et al. How ORAI and TRP channels interfere with each other: Interaction models and examples from the immune system and the skin.
Eur. J. Pharmacol., 2013 Nov 28 , ().

59

Little SC et al. TRPM4 modulates sinus node diastolic depolarization.
Heart Rhythm, 2013 Nov , 10 (1690-1).

60

Hof T et al. Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm.
Heart Rhythm, 2013 Nov , 10 (1683-9).

61

Smith AC et al. Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology.
Am. J. Physiol., Cell Physiol., 2013 Mar 1 , 304 (C467-77).

62

Simard C et al. The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential.
J. Mol. Cell. Cardiol., 2013 Jun , 59 (11-9).

63

Sah R et al. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization.
Circulation, 2013 Jul 9 , 128 (101-14).

64

Burt R et al. 9-Phenanthrol and flufenamic acid inhibit calcium oscillations in HL-1 mouse cardiomyocytes.
Cell Calcium, 2013 Jul 4 , ().

65

Kastenhuber E et al. Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes.
Dev. Dyn., 2013 Jul 31 , ().

66

Narayanan D et al. Smooth Muscle Cell Transient Receptor Potential Polycystin (TRPP)2 Channels Contribute To The Myogenic Response In Cerebral Arteries.
J. Physiol. (Lond.), 2013 Jul 15 , ().

67

Simon F et al. Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans.
Cell. Signal., 2013 Jul , 25 (1614-24).

68

Guinamard R et al. Flufenamic acid as an ion channel modulator.
Pharmacol. Ther., 2013 Jan 25 , ().

69

Nelson P et al. Transient receptor potential melastatin 4 channel controls calcium signals and dental follicle stem cell differentiation.
Stem Cells, 2013 Jan , 31 (167-77).

70

Woo SK et al. The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel.
J. Biol. Chem., 2013 Feb 1 , 288 (3655-67).

71

Smith PK et al. Transient Receptor Potentials (TRPs) and Anaphylaxis.
Curr Allergy Asthma Rep, 2013 Feb , 13 (93-100).

72

Woo SK et al. Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein.
J. Biol. Chem., 2013 Dec 20 , 288 (36409-17).

73

Tosun C et al. Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage.
Stroke, 2013 Dec , 44 (3522-8).

74

Malhotra S et al. TRPM4 mRNA expression levels in peripheral blood mononuclear cells from multiple sclerosis patients.
J. Neuroimmunol., 2013 Aug 15 , 261 (146-8).

75

Weston AH et al. Stimulated release of a hyperpolarizing factor (ADHF) from mesenteric artery perivascular adipose tissue: involvement of myocyte BKCa channels and adiponectin.
Br. J. Pharmacol., 2013 Aug , 169 (1500-9).

76

Amarouch MY et al. Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells.
Neurosci. Lett., 2013 Apr 29 , 541 (105-10).

77

Mironov SL Calmodulin and calmodulin kinase II mediate emergent bursting activity in the brainstem respiratory network (preBötzinger complex).
J. Physiol. (Lond.), 2013 Apr 1 , 591 (1613-30).

78

Smith AC et al. TRPM4 channel: a new player in urinary bladder smooth muscle function in rats.
Am. J. Physiol. Renal Physiol., 2013 Apr 1 , 304 (F918-29).

79

Kim EC et al. Role of Endogenous ENaC and TRP Channels in the Myogenic Response of Rat Posterior Cerebral Arteries.
PLoS ONE, 2013 , 8 (e84194).

80

Liu H et al. Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel.
PLoS ONE, 2013 , 8 (e54131).

81

Watanabe H et al. Possible involvement of TRP channels in cardiac hypertrophy and arrhythmia.
Curr Top Med Chem, 2013 , 13 (283-94).

82

Vandewauw I et al. Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse.
BMC Neurosci, 2013 , 14 (21).

83

Wang J et al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury.
PLoS ONE, 2013 , 8 (e70587).

84

Zhang YH et al. Evidence for functional expression of TRPM7 channels in human atrial myocytes.
Basic Res. Cardiol., 2012 Sep , 107 (282).

85

Serafini N et al. The TRPM4 channel controls monocyte and macrophage, but not neutrophil, function for survival in sepsis.
J. Immunol., 2012 Oct 1 , 189 (3689-99).

86

Abriel H et al. TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology.
Biochem. Pharmacol., 2012 Oct 1 , 84 (873-81).

87

Jang Y et al. Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res., 2012 Oct , 35 (1823-30).

88

Kim YS et al. Characterizing the conductance underlying depolarization-induced slow current (DISC) in cerebellar Purkinje cells.
J. Neurophysiol., 2012 Nov 28 , ().

89

Gonzales AL et al. Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca(2+) -activated Cation Channels.
Microcirculation, 2012 Nov 1 , ().

90

Sala-Rabanal M et al. On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1.
J. Biol. Chem., 2012 Mar 16 , 287 (8746-56).

91

Stallmeyer B et al. Mutational spectrum in the Ca(2+)--activated cation channel gene TRPM4 in patients with cardiac conductance disturbances.
Hum. Mutat., 2012 Jan , 33 (109-17).

92

Simard JM et al. Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury.
Exp. Neurol., 2012 Jan , 233 (566-74).

93

Gonzales AL et al. Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells.
Cell Calcium, 2012 Jan , 51 (82-93).

94

Gailly P TRP channels in normal and dystrophic skeletal muscle.
, 2012 Feb 18 , ().

95

Kim BJ et al. The role of transient receptor potential channel blockers in human gastric cancer cell viability.
Can. J. Physiol. Pharmacol., 2012 Feb , 90 (175-86).

96

Schattling B et al. TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.
Nat. Med., 2012 Dec 6 , 18 (1805-11).

97

Simard JM et al. Transient receptor potential melastatin 4 and cell death.
Pflugers Arch., 2012 Dec , 464 (573-82).

98

Simard C et al. Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle.
Br. J. Pharmacol., 2012 Apr , 165 (2354-64).

99

Kuras Z et al. KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells.
PLoS ONE, 2012 , 7 (e43859).

100

Garcia ZI et al. Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells.
Channels (Austin), 2011 May-Jun , 5 (210-4).

101

Walcott BP et al. Novel Treatment Targets for Cerebral Edema.
, 2011 Nov 29 , ().

102

Zierler S et al. Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels.
J. Biol. Chem., 2011 Nov 11 , 286 (39328-35).

103

Mrejeru A et al. Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta.
J. Physiol. (Lond.), 2011 May 15 , 589 (2497-514).

104

Becerra A et al. Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death.
, 2011 May 11 , ().

105

Nelson PL et al. Regulation of Ca(2+)-entry in pancreatic α-cell line by transient receptor potential melastatin 4 plays a vital role in glucagon release.
Mol. Cell. Endocrinol., 2011 Mar 30 , 335 (126-34).

106

Guinamard R et al. A calcium-permeable non-selective cation channel in the thick ascending limb apical membrane of the mouse kidney.
, 2011 Dec 31 , ().

107

Teruyama R et al. Transient receptor potential channel m4 and m5 in magnocellular cells in rat supraoptic and paraventricular nuclei.
J. Neuroendocrinol., 2011 Dec , 23 (1204-13).

108

Dwyer L et al. Basally activated nonselective cation currents regulate the resting membrane potential in human and monkey colonic smooth muscle.
Am. J. Physiol. Gastrointest. Liver Physiol., 2011 Aug , 301 (G287-96).

109

Mironov SL et al. Stimulation of bursting in pre-Bötzinger neurons by Epac through calcium release and modulation of TRPM4 and K-ATP channels.
J. Neurochem., 2011 Apr , 117 (295-308).

110

Zholos A et al. TRPM channels in the vasculature.
Adv. Exp. Med. Biol., 2011 , 704 (707-29).

111

Brinkmeier H TRP channels in skeletal muscle: gene expression, function and implications for disease.
Adv. Exp. Med. Biol., 2011 , 704 (749-58).

112

Thilo F et al. Decreased expression of transient receptor potential channels in cerebral vascular tissue from patients after hypertensive intracerebral hemorrhage.
Clin. Exp. Hypertens., 2011 , 33 (533-7).

113

Uchida K et al. The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion.
Endocr. J., 2011 , 58 (1021-8).

114

Takumida M et al. Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear.
Acta Otolaryngol., 2009 Oct , 129 (1050-60).