Referenced in: none

Automatically associated channels: Nav1.7 , TRP , TRPA , TRPA1 , TRPV , TRPV1

Title: Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity.

Authors: Thomas Stueber, Mirjam J Eberhardt, Christoph Hadamitzky, Annette Jangra, Stefan Schenk, Felicia Dick, Carsten Stoetzer, Katrin Kistner, Peter W Reeh, Alexander M Binshtok, Andreas Leffler

Journal, date & volume: Anesthesiology, 2016 Feb 9 , ,

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/26859646

Abstract