SK1

1

Xu S et al. A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.
Oncotarget, 2016 May 14 , ().

2

Tauseef M et al. Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability.
FASEB J., 2016 Jan , 30 (102-10).

3

Pisani DF et al. The K+ channel TASK1 modulates β-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway.
FASEB J., 2016 Feb , 30 (909-22).

4

Gandolfi B et al. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats.
Osteoarthr. Cartil., 2016 Apr 6 , ().

5

Rahman M et al. Electrophysiological characterization of voltage-dependent calcium currents and TRPV4 currents in human pulmonary fibroblasts.
Am. J. Physiol. Lung Cell Mol. Physiol., 2016 Apr 1 , 310 (L603-14).

6

Zhao Y et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord, 2016 , 16 (1).

7

Bhuyan R et al. Molecular dynamics of Kv1.3 ion channel and structural basis of its inhibition by scorpion toxin-OSK1 derivatives.
Biophys. Chem., 2015 Aug-Sep , 203-204 (1-11).

8

Jo AO et al. TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.
J. Neurosci., 2015 Sep 30 , 35 (13525-37).

9

Mizukami K et al. Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats.
Am. J. Physiol. Heart Circ. Physiol., 2015 Sep 15 , 309 (H1066-74).

10

Carretero L et al. ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells.
Cell. Signal., 2015 Sep , 27 (1720-30).

11

Rajasekhar P et al. P2Y1 receptor activation of the TRPV4 ion channel enhances purinergic signaling in satellite glial cells.
J. Biol. Chem., 2015 Oct 16 , ().

12

Hurd L et al. A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia.
Am. J. Med. Genet. A, 2015 Oct , 167A (2286-93).

13

Gao M et al. Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X(7) receptor.
Bioorg. Med. Chem. Lett., 2015 May 1 , 25 (1965-70).

14

Bandulik S et al. Two-pore domain potassium channels in the adrenal cortex.
Pflugers Arch., 2015 May , 467 (1027-42).

15

Ehling P et al. The CNS under pathophysiologic attack--examining the role of K₂p channels.
Pflugers Arch., 2015 May , 467 (959-72).

16

Buckler KJ TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing.
Pflugers Arch., 2015 May , 467 (1013-25).

17

Göb E et al. The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration.
Pflugers Arch., 2015 May , 467 (973-87).

18

De Clercq K et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle.
Hum. Reprod., 2015 Mar 27 , ().

19

Teng J et al. L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.
Proc. Natl. Acad. Sci. U.S.A., 2015 Mar 17 , 112 (3386-91).

20

Yi F et al. Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria.
J. Biol. Chem., 2015 Mar 13 , 290 (7016-26).

21

Deng Y et al. Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice.
Eur. J. Pharmacol., 2015 Mar 11 , ().

22

Larson RA et al. Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus.
Am. J. Physiol. Heart Circ. Physiol., 2015 Jun 15 , 308 (H1547-55).

23

Wilson PC et al. Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel.
Mol. Endocrinol., 2015 Jun , 29 (896-908).

24

Narita K et al. TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport.
FASEB J., 2015 Jun , 29 (2247-59).

25

Alkozi HA et al. TRPV4 activation triggers the release of melatonin from human non-pigmented ciliary epithelial cells.
Exp. Eye Res., 2015 Jul , 136 (34-7).

26

Cabral PD et al. TRPV4 mediates flow-induced increases in intracellular Ca in medullary thick ascending limbs.
Acta Physiol (Oxf), 2015 Jul , 214 (319-28).

27

Padula AE et al. KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.
Neuropsychopharmacology, 2015 Jul , 40 (1928-39).

28

Song J et al. The effect of ASK1 on vascular permeability and edema formation in cerebral ischemia.
Brain Res., 2015 Jan 21 , 1595 (143-55).

29

Dragoni S et al. A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.
J. Cell. Physiol., 2015 Jan , 230 (95-104).

30

Singh V et al. Molecular and functional characterization of TRPV4 channels in pregnant and nonpregnant mouse uterus.
Life Sci., 2015 Feb 1 , 122 (51-8).

31

Chen L et al. Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.
Acta Physiol (Oxf), 2015 Feb , 213 (481-91).

32

Church TW et al. Preferential assembly of heteromeric small conductance calcium-activated potassium channels.
Eur. J. Neurosci., 2015 Feb , 41 (305-15).

33

Suresh K et al. Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Dec 15 , 309 (L1467-77).

34

Baratchi S et al. Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.
Cell. Mol. Life Sci., 2015 Aug 20 , ().

35

Matsuoka H et al. Src mediates endocytosis of TWIK-related acid-sensitive K+ 1 channels in PC12 cells in response to nerve growth factor.
Am. J. Physiol., Cell Physiol., 2015 Aug 15 , 309 (C251-63).

36

Aidi-Knani S et al. Correspondences between the binding characteristics of a non-natural peptide, Lei-Dab7, and the distribution of SK subunits in the rat central nervous system.
Eur. J. Pharmacol., 2015 Apr 5 , 752 (106-11).

37

Ru F et al. Acid sensitivity of the spinal dorsal root ganglia C-fiber nociceptors innervating the guinea pig esophagus.
Neurogastroenterol. Motil., 2015 Apr 5 , ().

38

Farberov L et al. MicroRNA-mediated regulation of p21 and TASK1 cellular restriction factors enhances HIV-1 infection.
J. Cell. Sci., 2015 Apr 15 , 128 (1607-16).

39

Adapala RK et al. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.
Oncogene, 2015 Apr 13 , ().

40

Doleschal B et al. TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc. Res., 2015 Apr 1 , 106 (163-73).

41

Sostegni S et al. Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase.
Pflugers Arch., 2015 Apr , 467 (687-701).

42

Feetham CH et al. TRPV4 and KCa ion channels functionally couple as osmosensors in the paraventricular nucleus.
Br. J. Pharmacol., 2015 Apr , 172 (1753-68).

43

Nayak PS et al. Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells.
Respir. Res., 2015 , 16 (60).

44

Buckler KJ et al. Functional Properties of Mitochondria in the Type-1 Cell and Their Role in Oxygen Sensing.
Adv. Exp. Med. Biol., 2015 , 860 (69-80).

45

Kim I et al. Possible Role of TRP Channels in Rat Glomus Cells.
Adv. Exp. Med. Biol., 2015 , 860 (227-32).

46

Jie P et al. Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways.
Cell Death Dis, 2015 , 6 (e1775).

47

Monaghan K et al. Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium.
PLoS ONE, 2015 , 10 (e0128359).

48

Thoppil RJ et al. TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation.
Sci Rep, 2015 , 5 (14257).

49

Te Molder L et al. PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.
PLoS ONE, 2015 , 10 (e0143357).

50

Cabral PD et al. TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb.
Am. J. Physiol. Renal Physiol., 2014 Sep 15 , 307 (F666-72).

51

Egbuniwe O et al. TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.
J. Dent. Res., 2014 Sep , 93 (911-7).

52

Takayama Y et al. Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1.
FASEB J., 2014 May , 28 (2238-48).

53

Yu L et al. Neuroprotective effect of muscone on glutamate-induced apoptosis in PC12 cells via antioxidant and Ca(2+) antagonism.
Neurochem. Int., 2014 May , 70 (10-21).

54

Mercado J et al. Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle.
J. Gen. Physiol., 2014 May , 143 (559-75).

55

Guéguinou M et al. KCa and Ca(2+) channels: The complex thought.
Biochim. Biophys. Acta, 2014 Mar 6 , ().

56

Tran VT et al. Mechanotransduction channels of the trabecular meshwork.
Curr. Eye Res., 2014 Mar , 39 (291-303).

57

Merrill L et al. Intravesical TRPV4 blockade reduces repeated variate stress (RVS)-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2014 Jun 25 , ().

58

Skibsbye L et al. Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria.
Cardiovasc. Res., 2014 Jul 1 , 103 (156-67).

59

Ochoa-Cortés F et al. Potential for developing purinergic drugs for gastrointestinal diseases.
Inflamm. Bowel Dis., 2014 Jul , 20 (1259-87).

60

O'Conor CJ et al. TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jan 28 , 111 (1316-21).

61

El Hachmane MF et al. Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor α.
J. Biol. Chem., 2014 Jan 17 , 289 (1388-401).

62

Pankey EA et al. Analysis of responses to the TRPV4 agonist GSK1016790A in the pulmonary vascular bed of the intact-chest rat.
Am. J. Physiol. Heart Circ. Physiol., 2014 Jan 1 , 306 (H33-40).

63

Jablonski CL et al. Integrin α1β1 participates in chondrocyte transduction of osmotic stress.
Biochem. Biophys. Res. Commun., 2014 Feb 28 , 445 (184-90).

64

Zhang XD et al. Critical roles of a small conductance Ca²⁺-activated K⁺ channel (SK3) in the repolarization process of atrial myocytes.
Cardiovasc. Res., 2014 Feb 1 , 101 (317-25).

65

Dufour MA et al. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.
J. Neurosci. Res., 2014 Aug , 92 (981-99).

66

Grace MS et al. The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2 -induced Activation of TRPV4 In Vitro and Pain In Vivo.
Br. J. Pharmacol., 2014 Apr 30 , ().

67

Gymnopoulos M et al. Developmental mapping of small-conductance calcium-activated potassium channel expression in the rat nervous system.
J. Comp. Neurol., 2014 Apr 1 , 522 (1072-101).

68

McAlexander MA et al. Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes.
J. Pharmacol. Exp. Ther., 2014 Apr , 349 (118-25).

69

Dolga AM et al. Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.
Cell Death Dis, 2014 , 5 (e999).

70

Shenton F et al. A study of the expression of small conductance calcium-activated potassium channels (SK1-3) in sensory endings of muscle spindles and lanceolate endings of hair follicles in the rat.
PLoS ONE, 2014 , 9 (e107073).

71

Son SM et al. Reduced IRE1α mediates apoptotic cell death by disrupting calcium homeostasis via the InsP3 receptor.
Cell Death Dis, 2014 , 5 (e1188).

72

Cabo R et al. Calcium-activated potassium channel SK1 is widely expressed in the peripheral nervous system and sensory organs of adult zebrafish.
Neurosci. Lett., 2013 Sep 21 , ().

73

Alenmyr L et al. TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells.
Basic Clin. Pharmacol. Toxicol., 2013 Sep 11 , ().

74

de Haan JJ et al. Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex.
Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Sep 1 , 305 (G383-91).

75

Kieseier BC et al. Targeting two-pore domain potassium channels - a promising strategy for treating T cell mediated autoimmunity.
Exp. Neurol., 2013 Sep , 247 (286-8).

76

Liu Y et al. Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle.
Cell. Signal., 2013 Sep , 25 (1877-86).

77

Chen R et al. Molecular dynamics simulations of scorpion toxin recognition by the Ca(2+)-activated potassium channel KCa3.1.
Biophys. J., 2013 Oct 15 , 105 (1829-37).

78

Zhang L et al. Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease.
Br. J. Pharmacol., 2013 Oct , 170 (661-70).

79

Xi B et al. Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
Clin. Endocrinol. (Oxf), 2013 Oct , 79 (523-8).

80

Qi XY et al. Role of Small Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog.
Circulation, 2013 Nov 4 , ().

81

Pollema-Mays SL et al. Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain model.
Mol. Cell. Neurosci., 2013 Nov , 57 (1-9).

82

Wu W et al. EGFR tyrosine kinase regulates human small-conductance Ca2+-activated K+ (hSKCa1) channels expressed in HEK-293 cells.
Biochem. J., 2013 May 15 , 452 (121-9).

83

Matsuoka H et al. Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K⁺ 1 channels in adrenal medullary cells and PC12 cells.
Pflugers Arch., 2013 Jul , 465 (1051-64).

84

Linta L et al. Calcium activated potassium channel expression during human iPS cell-derived neurogenesis.
Ann. Anat., 2013 Jul , 195 (303-11).

85

Dreses-Werringloer U et al. CALHM1 controls Ca2+-dependent MEK/ERK/RSK/MSK signaling in neurons.
J. Cell. Sci., 2013 Jan 23 , ().

86

Al Ghouleh I et al. Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy.
Cardiovasc. Res., 2013 Jan 1 , 97 (134-42).

87

Mubagwa K Signalling between G-protein-coupled receptors and TASK1 channels.
Cardiovasc. Res., 2013 Jan 1 , 97 (10-2).

88

Ali Z et al. Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.
Br J Clin Pharmacol, 2013 Jan , 75 (197-207).

89

Young JS et al. The passive and active contractile properties of the neurogenic, underactive bladder.
BJU Int., 2013 Feb , 111 (355-61).

90

Alexander R et al. 4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4.
Br. J. Pharmacol., 2013 Feb , 168 (761-72).

91

Schmidt C et al. Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels.
Eur. J. Pharmacol., 2013 Dec 5 , 721 (237-48).

92

Ni Y et al. Bisoprolol reversed small conductance calcium-activated potassium channel (SK) remodeling in a volume-overload rat model.
Mol. Cell. Biochem., 2013 Dec , 384 (95-103).

93

Sukumaran SV et al. TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery.
Pharmacol. Res., 2013 Dec , 78 (18-27).

94

Pagadala P et al. Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels.
J. Neurosci., 2013 Aug 14 , 33 (13425-30).

95

Parajuli SP et al. NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels.
Br. J. Pharmacol., 2013 Apr , 168 (1611-25).

96

Atkinson AJ et al. Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.
J Am Heart Assoc, 2013 , 2 (e000246).

97

Lübbert M et al. Transient receptor potential channels encode volatile chemicals sensed by rat trigeminal ganglion neurons.
PLoS ONE, 2013 , 8 (e77998).

98

Corrêa SA et al. MSK1 regulates homeostatic and experience-dependent synaptic plasticity.
J. Neurosci., 2012 Sep 19 , 32 (13039-51).

99

Andres MA Glucose-sensitivity of the afterhyperpolarization potential: role of SK1 channel in insulin-secreting cells.
Gen. Comp. Endocrinol., 2012 Sep 15 , 178 (459-62).

100

Inoue M et al. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.
Am. J. Physiol., Cell Physiol., 2012 Sep 15 , 303 (C635-44).

101

Sullivan MN et al. Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells.
Mol. Pharmacol., 2012 Sep , 82 (464-72).

102

Schmidt C et al. Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels.
Naunyn Schmiedebergs Arch. Pharmacol., 2012 Oct , 385 (1003-16).

103

Vandael DH et al. Ca(V)1.3-driven SK channel activation regulates pacemaking and spike frequency adaptation in mouse chromaffin cells.
J. Neurosci., 2012 Nov 14 , 32 (16345-59).

104

Murphy N et al. The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells.
Brain Pathol., 2012 May , 22 (295-306).

105

Chen R et al. Engineering a potent and specific blocker of voltage-gated potassium channel Kv1.3, a target for autoimmune diseases.
Biochemistry, 2012 Mar 6 , 51 (1976-82).

106

Berrout J et al. Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system.
J. Biol. Chem., 2012 Mar 16 , 287 (8782-91).

107

Marsh B et al. Leak K⁺ channel mRNAs in dorsal root ganglia: relation to inflammation and spontaneous pain behaviour.
Mol. Cell. Neurosci., 2012 Mar , 49 (375-86).

108

Seyler C et al. TASK1 (K(2P)3.1) K(+) channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylation.
Br. J. Pharmacol., 2012 Mar , 165 (1467-75).

109

Shahidullah M et al. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity.
Am. J. Physiol., Cell Physiol., 2012 Jun , 302 (C1751-61).

110

Chubanov V et al. Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.
, 2012 Jan 13 , ().

111

Parajuli SP et al. Pharmacological activation of small conductance calcium-activated potassium channels with naphtho[1,2-d]thiazol-2-ylamine decreases guinea pig detrusor smooth muscle excitability and contractility.
J. Pharmacol. Exp. Ther., 2012 Jan , 340 (114-23).

112

Aizawa N et al. Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.
Neurourol. Urodyn., 2012 Jan , 31 (148-55).

113

Park SW et al. Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury.
J. Am. Soc. Nephrol., 2012 Feb , 23 (266-80).

114

Jin M et al. Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channels.
Cell Calcium, 2012 Feb , 51 (131-9).

115

Zhang Y et al. TRPV4 activation in mouse submandibular gland modulates Ca2+ influx and salivation.
Am. J. Physiol. Gastrointest. Liver Physiol., 2012 Dec 15 , 303 (G1365-72).

116

Bittner S et al. The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis.
Exp. Neurol., 2012 Dec , 238 (149-55).

117

Penton D et al. Task3 Potassium Channel Gene Invalidation Causes Low Renin and Salt-Sensitive Arterial Hypertension.
Endocrinology, 2012 Aug 9 , ().

118

Buttigieg J et al. NOX2 (gp91 phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular and electrophysiological evidence.
Am. J. Physiol. Lung Cell Mol. Physiol., 2012 Aug 3 , ().

119

Afeli SA et al. SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions.
Am. J. Physiol. Renal Physiol., 2012 Aug 15 , 303 (F559-68).

120

Gui L et al. Role of small conductance calcium-activated potassium channels expressed in PVN in regulating sympathetic nerve activity and arterial blood pressure in rats.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2012 Aug 1 , 303 (R301-10).

121

McHugh SM et al. Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach.
Br J Clin Pharmacol, 2012 Aug , 74 (376-80).

122

Kida N et al. Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes.
Pflugers Arch., 2012 Apr , 463 (715-25).

123

Evans AM et al. Ion Channel Regulation by the LKB1-AMPK Signalling Pathway: The Key to Carotid Body Activation by Hypoxia and Metabolic Homeostasis at the Whole Body Level.
Adv. Exp. Med. Biol., 2012 , 758 (81-90).

124

Lim M et al. The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries.
PLoS ONE, 2012 , 7 (e35177).

125

van der Zanden EP et al. Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals.
Neuroimmunomodulation, 2012 , 19 (255-65).

126

Girault A et al. Targeting SKCa channels in cancer: potential new therapeutic approaches.
Curr. Med. Chem., 2012 , 19 (697-713).

127

Weatherall KL et al. Crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of small-conductance calcium-activated potassium (SK) channels.
Proc. Natl. Acad. Sci. U.S.A., 2011 Nov 8 , 108 (18494-9).

128

Mergler S et al. Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells.
Exp. Eye Res., 2011 Nov , 93 (710-9).

129

Girault A et al. New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Curr Cancer Drug Targets, 2011 Nov , 11 (1111-25).

130

Basalingappa KM et al. Characteristics of Kcnn4 channels in the apical membranes of an intestinal epithelial cell line.
Am. J. Physiol. Gastrointest. Liver Physiol., 2011 Nov , 301 (G905-11).

131

Lamande SR et al. Mutations in TRPV4 cause an inherited arthropathy of hands and feet.
Nat. Genet., 2011 Nov , 43 (1142-6).

132

Bobak N et al. Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels.
, 2011 May 5 , ().

133

Yanni J et al. Changes in Ion Channel Gene Expression Underlying Heart Failure-induced Sinoatrial Node Dysfunction.
, 2011 May 12 , ().

134

Ryskamp DA et al. The Polymodal Ion Channel Transient Receptor Potential Vanilloid 4 Modulates Calcium Flux, Spiking Rate, and Apoptosis of Mouse Retinal Ganglion Cells.
, 2011 May 11 , 31 (7089-7101).

135

Basso M et al. Polymorphism of CAG motif of SK3 gene is associated with acute oxaliplatin neurotoxicity.
Cancer Chemother. Pharmacol., 2011 May , 67 (1179-87).

136

Yu T et al. [Expression and functional role of small conductance Ca(2+)-activated K(+) channels in human atrial myocytes].
Nan Fang Yi Ke Da Xue Xue Bao, 2011 Mar , 31 (490-4).

137

Kazmierski WM et al. Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.
J. Med. Chem., 2011 Jun 9 , 54 (3756-67).

138

Vincent F et al. TRPV4 Agonists and Antagonists.
, 2011 Jun 14 , ().

139

Staudacher K et al. Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels.
Br. J. Pharmacol., 2011 Jul , 163 (1099-110).

140

Chen R et al. Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3).
Biophys. J., 2011 Dec 7 , 101 (2652-60).

141

Yu T et al. Decreased expression of small-conductance Ca(2+)-activated K(+) channels SK1 and SK2 in human chronic atrial fibrillation.
, 2011 Dec 1 , ().

142

Prüss H et al. Potassium channel expression in adult murine neural progenitor cells.
Neuroscience, 2011 Apr 28 , 180 (19-29).

143

Jin M et al. Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A.
PLoS ONE, 2011 , 6 (e16713).

144

Gao C et al. Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.
Hippocampus, 2010 Sep , 20 (1072-82).

145

Behm DJ et al. GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo.
Br. J. Pharmacol., 2010 Sep , 161 (207-28).

146

Ernest NJ et al. Biophysical Properties of Human Medulloblastoma Cells.
, 2010 Oct 8 , ().

147

Tuteja D et al. Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.
Circ. Res., 2010 Oct 1 , 107 (851-9).

148

Bittner S et al. From the background to the spotlight: TASK channels in pathological conditions.
Brain Pathol., 2010 Nov , 20 (999-1009).

149

Snoek SA et al. Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis.
Br. J. Pharmacol., 2010 May , 160 (322-33).

150

Kita M et al. Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2010 May , 298 (R1310-9).

151

Samovski D et al. Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo.
J. Biol. Chem., 2010 Mar 5 , 285 (6879-90).

152

Tang K et al. Role of ASK1-JNK-p38 Signaling in Kv Channel Remodeling of the Failing Heart: Regulation by Thioredoxin.
, 2010 Jun 2 , ().

153

Bandulik S et al. TASK1 and TASK3 potassium channels: determinants of aldosterone secretion and adrenocortical zonation.
Horm. Metab. Res., 2010 Jun , 42 (450-7).

154

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