Nav1.4

1

Mulcahy JV et al. Synthesis of the Paralytic Shellfish Poisons (+)-Gonyautoxin 2, (+)-Gonyautoxin 3, and (+)-11,11-Dihydroxysaxitoxin.
J. Am. Chem. Soc., 2016 May 11 , 138 (5994-6001).

2

Patel D et al. Computational Study of Binding of μ-Conotoxin GIIIA to Bacterial Sodium Channels NaVAb and NaVRh.
Biochemistry, 2016 Mar 29 , 55 (1929-38).

3

Tao H et al. Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels.
Toxicon, 2016 Mar 1 , 111 (13-21).

4

Tarvin RD et al. Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison Frogs.
Mol. Biol. Evol., 2016 Jan 18 , ().

5

Habbout K et al. A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis.
Neurology, 2016 Jan 12 , 86 (161-9).

6

Shcherbatko A et al. Engineering Highly Potent and Selective Microproteins Against Nav1.7 Sodium Channel for Treatment of Pain.
J. Biol. Chem., 2016 Apr 22 , ().

7

Zhao Y et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord, 2016 , 16 (1).

8

Coll M et al. Genetic investigation of sudden unexpected death in epilepsy cohort by panel target resequencing.
Int. J. Legal Med., 2015 Sep 30 , ().

9

Nicole S et al. Skeletal muscle sodium channelopathies.
Curr. Opin. Neurol., 2015 Oct , 28 (508-514xs).

10

Lee YH et al. Whole-Body Muscle MRI in Patients with Hyperkalemic Periodic Paralysis Carrying the SCN4A Mutation T704M: Evidence for Chronic Progressive Myopathy with Selective Muscle Involvement.
J Clin Neurol, 2015 Oct , 11 (331-8).

11

Torbergsen T et al. Painful cramps and giant myotonic discharges in a family with the Nav1.4-G1306A mutation.
Muscle Nerve, 2015 Oct , 52 (680-3).

12

Fusco C et al. New phenotype and neonatal onset of sodium channel myotonia in a child with a novel mutation of SCN4A gene.
Brain Dev., 2015 Oct , 37 (891-3).

13

Basali D et al. Episodic weakness and vacuolar myopathy in hypokalemic periodic paralysis.
J Clin Neurosci, 2015 Nov , 22 (1846-7).

14

Gawali VS et al. Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels.
Mol. Pharmacol., 2015 Nov , 88 (866-79).

15

Arnold WD et al. Defective fast inactivation recovery of Nav 1.4 in congenital myasthenic syndrome.
Ann. Neurol., 2015 May , 77 (840-50).

16

Yoshinaga H et al. Phenotypic variability in childhood of skeletal muscle sodium channelopathies.
Pediatr. Neurol., 2015 May , 52 (504-8).

17

Murray JK et al. Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel.
J. Med. Chem., 2015 Mar 12 , 58 (2299-314).

18

Jia BX et al. Muscle edema of the lower limb determined by MRI in Asian hypokalaemic periodic paralysis patients.
Neurol. Res., 2015 Mar , 37 (246-52).

19

Cai T et al. Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels.
Peptides, 2015 Jun , 68 (148-56).

20

Slowik D et al. Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference.
Biochim. Biophys. Acta, 2015 Jul , 1848 (1545-51).

21

Cao L et al. Normokalemic periodic paralysis with involuntary movements and generalized epilepsy associated with two novel mutations in SCN4A gene.
Seizure, 2015 Jan , 24 (134-6).

22

Hanifin CT et al. Evolutionary history of a complex adaptation: tetrodotoxin resistance in salamanders.
Evolution, 2015 Jan , 69 (232-44).

23

Ednie AR et al. Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating.
Biochim. Biophys. Acta, 2015 Feb , 1850 (307-17).

24

Zhang H et al. Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5.
Mol. Pharmacol., 2015 Feb , 87 (207-17).

25

Tikhonov DB et al. State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels.
Pflugers Arch., 2015 Feb , 467 (253-66).

26

Zaharieva IT et al. Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or 'classical' congenital myopathy.
Brain, 2015 Dec 22 , ().

27

Pucca MB et al. Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages.
Biochimie, 2015 Aug , 115 (8-16).

28

Cannon SC Channelopathies of skeletal muscle excitability.
Compr Physiol, 2015 Apr , 5 (761-90).

29

Bugiardini E et al. SCN4A mutation as modifying factor of myotonic dystrophy type 2 phenotype.
Neuromuscul. Disord., 2015 Apr , 25 (301-7).

30

Mahdavi S et al. Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels.
PLoS ONE, 2015 , 10 (e0133000).

31

Subramanian M et al. Idiopathic generalized epilepsy and hypokalemic periodic paralysis in a family of South Indian descent.
Case Rep Neurol Med, 2015 , 2015 (906049).

32

Brun J et al. Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells.
PLoS ONE, 2015 , 10 (e0145153).

33

Gu H et al. cAMP/PKA Pathways and S56 Phosphorylation Are Involved in AA/PGE2-Induced Increases in rNaV1.4 Current.
PLoS ONE, 2015 , 10 (e0140715).

34

Liu XL et al. Mutations of SCN4A gene cause different diseases: 2 case reports and literature review.
Channels (Austin), 2015 , 9 (82-7).

35

Xu C et al. Phenotypic variation of Val1589Met mutation in a four-generation Chinese pedigree with mild paramyotonia congenitia: case report.
Int J Clin Exp Pathol, 2015 , 8 (1050-6).

36

Camargos TS et al. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.
PLoS ONE, 2015 , 10 (e0128578).

37

Stunnenberg BC et al. Cardiac arrhythmias in hypokalemic periodic paralysis: Hypokalemia as only cause?
Muscle Nerve, 2014 Sep , 50 (327-32).

38

Korkosh VS et al. Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4.
J. Gen. Physiol., 2014 Sep , 144 (231-44).

39

Green BR et al. Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity.
Future Med Chem, 2014 Oct , 6 (1677-98).

40

Singh RR et al. Mutations in SCN4A: a rare but treatable cause of recurrent life-threatening laryngospasm.
Pediatrics, 2014 Nov , 134 (e1447-50).

41

Xu L et al. Functional characterization of two novel scorpion sodium channel toxins from Lychas mucronatus.
Toxicon, 2014 Nov , 90 (318-25).

42

McGlothlin JW et al. Parallel evolution of tetrodotoxin resistance in three voltage-gated sodium channel genes in the garter snake Thamnophis sirtalis.
Mol. Biol. Evol., 2014 Nov , 31 (2836-46).

43

Furby A et al. Heterozygous CLCN1 mutations can modulate phenotype in sodium channel myotonia.
Neuromuscul. Disord., 2014 Nov , 24 (953-9).

44

Holzherr B et al. A gating model for wildtype and R1448H Nav1.4 channels in paramyotonia.
Acta Myol, 2014 May , 33 (22-33).

45

Pless SA et al. Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains.
J. Gen. Physiol., 2014 May , 143 (645-56).

46

Dabby R et al. Myotonia in DNM2-related centronuclear myopathy.
J Neural Transm, 2014 May , 121 (549-53).

47

Zidar N et al. Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators.
Eur J Med Chem, 2014 Mar 3 , 74 (23-30).

48

Chen R et al. Mechanism of tetrodotoxin block and resistance in sodium channels.
Biochem. Biophys. Res. Commun., 2014 Mar 28 , 446 (370-4).

49

Kaczmarski JA et al. Investigating the size and dynamics of voltage-gated sodium channel fenestrations: A molecular dynamics study.
Channels (Austin), 2014 Mar 14 , 8 ().

50

Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

51

Ben-Johny M et al. Conservation of Ca(2+)/Calmodulin Regulation across Na and Ca(2+) Channels.
Cell, 2014 Jun 19 , 157 (1657-70).

52

Lukacs P et al. Exploring the Structure of the Voltage-Gated Na+ Channel by an Engineered Drug Access Pathway to the Receptor Site for Local Anesthetics.
J. Biol. Chem., 2014 Jun 19 , ().

53

Lucas B et al. Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant NaV1.4 channels do not correlate with Na+ influx or channel content.
Physiol. Genomics, 2014 Jun 1 , 46 (385-97).

54

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

55

Wu L et al. Enhanced slow inactivation of the human skeletal muscle sodium channel causing normokalemic periodic paralysis.
Cell. Mol. Neurobiol., 2014 Jul , 34 (707-14).

56

Jones JM et al. Modeling human epilepsy by TALEN targeting of mouse sodium channel Scn8a.
Genesis, 2014 Feb , 52 (141-8).

57

Corrochano S et al. Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis.
Brain, 2014 Dec , 137 (3171-85).

58

Mi W et al. Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis.
J. Gen. Physiol., 2014 Aug , 144 (137-45).

59

Thompson A et al. Expression Evolution Facilitated the Convergent Neofunctionalization of a Sodium Channel Gene.
Mol. Biol. Evol., 2014 Apr 29 , ().

60

Groome JR et al. NaV1.4 mutations cause hypokalaemic periodic paralysis by disrupting IIIS4 movement during recovery.
Brain, 2014 Apr , 137 (998-1008).

61

Zapata M et al. Molecular cloning of ion channels in Felis catus that are related to periodic paralyses in man: a contribution to the understanding of the genetic susceptibility to feline neck ventroflexion and paralysis.
Biol Open, 2014 , 3 (785-93).

62

Luo J et al. Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.
Toxins (Basel), 2014 , 6 (2177-93).

63

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

64

Shiga K et al. [Normokalemic periodic paralysis lasting for two weeks: a severe form of sodium channelopathy with M1592V mutation].
Rinsho Shinkeigaku, 2014 , 54 (434-9).

65

Mahdavi S et al. Systematic study of binding of μ-conotoxins to the sodium channel NaV1.4.
Toxins (Basel), 2014 , 6 (3454-70).

66

Amarouch MY et al. Functional interaction between S1 and S4 segments in voltage-gated sodium channels revealed by human channelopathies.
Channels (Austin), 2014 , 8 (414-20).

67

Yang B et al. A rare case of unilateral adrenal hyperplasia accompanied by hypokalaemic periodic paralysis caused by a novel dominant mutation in CACNA1S: features and prognosis after adrenalectomy.
BMC Urol, 2014 , 14 (96).

68

Magot A et al. Focal and abnormally persistent paralysis associated with congenital paramyotonia.
BMJ Case Rep, 2014 , 2014 ().

69

Mahdavi S et al. Molecular dynamics study of binding of µ-conotoxin GIIIA to the voltage-gated sodium channel Na(v)1.4.
PLoS ONE, 2014 , 9 (e105300).

70

Chen R et al. Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.
PLoS ONE, 2014 , 9 (e93267).

71

Hernãndez-Ochoa EO et al. Elevated nuclear Foxo1 suppresses excitability of skeletal muscle fibers.
Am. J. Physiol., Cell Physiol., 2013 Sep 15 , 305 (C643-53).

72

Oliveira EE et al. A residue in the transmembrane segment 6 of domain I in insect and mammalian sodium channels regulate differential sensitivities to pyrethroid insecticides.
Neurotoxicology, 2013 Sep , 38 (42-50).

73

Zhu L et al. Two recombinant α-like scorpion toxins from Mesobuthus eupeus with differential affinity toward insect and mammalian Na(+) channels.
Biochimie, 2013 Sep , 95 (1732-40).

74

Caietta E et al. Diagnosis and outcome of SCN4A-related severe neonatal episodic laryngospasm (SNEL): 2 new cases.
Pediatrics, 2013 Sep , 132 (e784-7).

75

Lewis AH et al. Interactions among DIV voltage-sensor movement, fast inactivation, and resurgent Na current induced by the NaVβ4 open-channel blocking peptide.
J. Gen. Physiol., 2013 Sep , 142 (191-206).

76

Black JA et al. Noncanonical roles of voltage-gated sodium channels.
Neuron, 2013 Oct 16 , 80 (280-91).

77

Argyriou AA et al. Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: results from a prospective multicenter study.
Cancer, 2013 Oct 1 , 119 (3570-7).

78

Wu M et al. A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating.
J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol., 2013 Oct , 199 (829-42).

79

Westenbroek RE et al. Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry.
J. Mol. Cell. Cardiol., 2013 Nov , 64 (69-78).

80

Groome JR et al. S1-S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation.
J. Gen. Physiol., 2013 May , 141 (601-18).

81

Nam TS et al. An algorithm for candidate sequencing in non-dystrophic skeletal muscle channelopathies.
J. Neurol., 2013 Jul , 260 (1770-7).

82

Wei CJ et al. [Clinical and molecular genetic analysis of a family with normokalemic periodic paralysis].
Zhonghua Er Ke Za Zhi, 2013 Jan , 51 (47-51).

83

Desaphy JF et al. Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials.
Mol. Pharmacol., 2013 Feb , 83 (406-15).

84

Wu F et al. Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis.
Brain, 2013 Dec , 136 (3766-74).

85

Stevens M et al. Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.
J. Neuroimmunol., 2013 Aug 15 , 261 (21-8).

86

Lee E et al. A patient with mutation in the SCN4A p.M1592v presenting with fixed weakness, rhabdomyolysis, and episodic worsening of weakness.
Muscle Nerve, 2013 Aug , 48 (306-7).

87

Morrow JM et al. Muscle MRI reveals distinct abnormalities in genetically proven non-dystrophic myotonias.
Neuromuscul. Disord., 2013 Aug , 23 (637-46).

88

Kaufmann SG et al. Distribution and function of sodium channel subtypes in human atrial myocardium.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (133-41).

89

Mourão CB et al. Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment to the HWTX-II family.
Biochemistry, 2013 Apr 9 , 52 (2440-52).

90

Horga A et al. Prevalence study of genetically defined skeletal muscle channelopathies in England.
Neurology, 2013 Apr 16 , 80 (1472-5).

91

Lossin C Nav 1.4 slow-inactivation: is it a player in the warm-up phenomenon of myotonic disorders?
Muscle Nerve, 2013 Apr , 47 (483-7).

92

Goldschen-Ohm MP et al. Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel.
Nat Commun, 2013 , 4 (1350).

93

Hehir MK et al. Double trouble in a patient with myotonia.
BMJ Case Rep, 2013 , 2013 ().

94

Ma Z et al. Direct Evidence that Scorpion α-Toxins (Site-3) Modulate Sodium Channel Inactivation by Hindrance of Voltage-Sensor Movements.
PLoS ONE, 2013 , 8 (e77758).

95

Nakatani Y et al. Effect of lamotrigine on Na(v)1.4 voltage-gated sodium channels.
J. Pharmacol. Sci., 2013 , 123 (203-6).

96

Zhou X et al. Modulation of mononuclear phagocyte inflammatory response by liposome-encapsulated voltage gated sodium channel inhibitor ameliorates myocardial ischemia/reperfusion injury in rats.
PLoS ONE, 2013 , 8 (e74390).

97

Islas AA et al. Identification of Navβ1 residues involved in the modulation of the sodium channel Nav1.4.
PLoS ONE, 2013 , 8 (e81995).

98

Biswas S et al. Mechanisms of a human skeletal myotonia produced by mutation in the C-terminus of NaV1.4: is Ca2+ regulation defective?
PLoS ONE, 2013 , 8 (e81063).

99

Durek T et al. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1.
ACS Chem. Biol., 2013 , 8 (1215-22).

100

Lossin C et al. Altered fast and slow inactivation of the N440K Nav1.4 mutant in a periodic paralysis syndrome.
Neurology, 2012 Sep 4 , 79 (1033-40).

101

Huang CJ et al. Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.
J. Gen. Physiol., 2012 Oct , 140 (435-54).

102

Nurputra DK et al. Paramyotonia congenita: from clinical diagnosis to in silico protein modeling analysis.
Pediatr Int, 2012 Oct , 54 (602-12).

103

Gosselin-Badaroudine P et al. Gating pore currents and the resting state of Nav1.4 voltage sensor domains.
Proc. Natl. Acad. Sci. U.S.A., 2012 Nov 20 , 109 (19250-5).

104

Hodgdon KE et al. Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Neuroscience, 2012 Mar 29 , 206 (237-44).

105

O'Reilly JP et al. Time- and state-dependent effects of methanethiosulfonate ethylammonium (MTSEA) exposure differ between heart and skeletal muscle voltage-gated Na(+) channels.
Biochim. Biophys. Acta, 2012 Mar , 1818 (443-7).

106

Mazón MJ et al. Screening for mutations in Spanish families with myotonia. Functional analysis of novel mutations in CLCN1 gene.
Neuromuscul. Disord., 2012 Mar , 22 (231-43).

107

Kokunai Y et al. A sodium channel myotonia due to a novel SCN4A mutation accompanied by acquired autoimmune myasthenia gravis.
Neurosci. Lett., 2012 Jun 21 , 519 (67-72).

108

Zhao J et al. Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians.
J. Physiol. (Lond.), 2012 Jun 1 , 590 (2629-44).

109

Catalano A et al. An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite.
Drug Metab Lett, 2012 Jun 1 , 6 (124-8).

110

Leffler A et al. Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine.
Anesthesiology, 2012 Jun , 116 (1335-46).

111

Fu LY et al. Sensitivity of cloned muscle, heart and neuronal voltage-gated sodium channels to block by polyamines: A possible basis for modulation of excitability in vivo.
, 2012 Jan 1 , 6 ().

112

Luca AD et al. Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.
Neuromuscul. Disord., 2012 Jan , 22 (56-65).

113

Song YW et al. Normokalemic periodic paralysis is not a distinct disease.
Muscle Nerve, 2012 Dec , 46 (914-6).

114

Du H et al. Myotonia congenita with strabismus in a large family with a mutation in the SCN4A gene.
Eye (Lond), 2012 Aug , 26 (1039-43).

115

Yoshinaga H et al. A novel mutation in SCN4A causes severe myotonia and school-age-onset paralytic episodes.
J. Neurol. Sci., 2012 Apr 15 , 315 (15-9).

116

Sung CC et al. Genotype and phenotype analysis of patients with sporadic periodic paralysis.
Am. J. Med. Sci., 2012 Apr , 343 (281-5).

117

Won YJ et al. Characterization of na(+) and ca(2+) channels in zebrafish dorsal root ganglion neurons.
PLoS ONE, 2012 , 7 (e42602).

118

Foadi N et al. Interaction of alfaxalone with the neuronal and the skeletal muscle sodium channel.
Pharmacology, 2012 , 89 (295-302).

119

Bissay V et al. A novel mutation in the SCN4A responsible for cold-induced myotonia with normal electromyography findings on room temperature.
J. Neurol. Sci., 2011 Sep 15 , 308 (162-4).

120

Wu F et al. A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis.
J. Clin. Invest., 2011 Oct 3 , 121 (4082-94).

121

Burge JA et al. Novel Insights into the Pathomechanisms of Skeletal Muscle Channelopathies.
, 2011 Nov 15 , ().

122

Kim H et al. Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations.
Korean J Pediatr, 2011 Nov , 54 (473-6).

123

Byers MR et al. Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels.
Arch. Oral Biol., 2011 Nov , 56 (1199-220).

124

Tammaro A et al. Novel missense mutations and unexpected multiple changes of RYR1 gene in 75 malignant hyperthermia families.
Clin. Genet., 2011 May , 79 (438-47).

125

Kubota T et al. A mutation in a rare type of intron in a sodium-channel gene results in aberrant splicing and causes myotonia.
, 2011 Mar 15 , ().

126

Simkin D et al. Mechanisms underlying a life-threatening skeletal muscle Na+ channel disorder.
J. Physiol. (Lond.), 2011 Jul 1 , 589 (3115-24).

127

Tikhonov DB et al. Possible roles of exceptionally conserved residues around the selectivity filters of sodium and calcium channels.
J. Biol. Chem., 2011 Jan 28 , 286 (2998-3006).

128

Anyukhovsky EP et al. Expression of skeletal muscle sodium channel (Nav1.4) or connexin32 prevents reperfusion arrhythmias in murine heart.
Cardiovasc. Res., 2011 Jan 1 , 89 (41-50).

129

Matthews E et al. Stridor as a neonatal presentation of skeletal muscle sodium channelopathy.
Arch. Neurol., 2011 Jan , 68 (127-9).

130

Widmark J et al. Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.
Mol. Biol. Evol., 2011 Jan , 28 (859-71).

131

Chen Z et al. ImKTx1, a new Kv1.3 channel blocker with a unique primary structure.
, 2011 Feb 9 , ().

132

Kasama S et al. [A case of muscle sodium channelopathy with markedly high value of serum creatine kinase and mild eyelid myotonia].
Rinsho Shinkeigaku, 2011 Feb , 51 (120-4).

133

Modoni A et al. Low-rate repetitive nerve stimulation protocol in an Italian cohort of patients affected by recessive myotonia congenita.
J Clin Neurophysiol, 2011 Feb , 28 (39-44).

134

Sun C et al. Myotonia congenita and myotonic dystrophy in the same family: coexistence of a CLCN1 mutation and expansion in the CNBP (ZNF9) gene.
Clin. Genet., 2011 Dec , 80 (574-80).

135

Baroni D et al. Molecular differential expression of voltage-gated sodium channel α and β subunit mRNAs in five different mammalian cell lines.
J. Bioenerg. Biomembr., 2011 Dec , 43 (729-38).

136

Bissay V et al. Late onset painful cold-aggravated myotonia: three families with SCN4A L1436P mutation.
Neuromuscul. Disord., 2011 Aug , 21 (590-3).

137

Feng Y et al. Severe phenotypes of paralysis periodica paramyotonia are associated with the Met1592Val mutation in the voltage-gated sodium channel gene (SCN4A) in a Chinese family.
J Clin Neurosci, 2011 Aug , 18 (1138-40).

138

Ahrens J et al. Defective polysialylation and sialylation induce opposite effects on gating of the skeletal Na+ channel NaV1.4 in Chinese hamster ovary cells.
Pharmacology, 2011 , 87 (311-7).

139

Incecik F et al. Hypokalemic periodic paralysis due to the SCN4A R672H mutation in a Turkish family.
Turk. J. Pediatr., 2010 Jul-Aug , 52 (409-10).

140

Wang SY et al. Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner.
Anesthesiology, 2010 Sep , 113 (655-65).

141

Zarrabi T et al. A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel.
, 2010 Oct 6 , ().

142

Raja Rayan DL et al. Skeletal muscle channelopathies: nondystrophic myotonias and periodic paralysis.
Curr. Opin. Neurol., 2010 Oct , 23 (466-76).

143

Park JH et al. A case of paramyotonia congenita without periodic paralysis: electrophysiological and molecular genetic studies.
Neurologist, 2010 May , 16 (203-5).

144

Gao R et al. Expression of voltage-gated sodium channel alpha subunit in human ovarian cancer.
Oncol. Rep., 2010 May , 23 (1293-9).

145

Stunnenberg BC et al. Isolated eyelid closure myotonia in two families with sodium channel myotonia.
Neurogenetics, 2010 May , 11 (257-60).

146

Zhou H et al. Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene.
Neuromuscul. Disord., 2010 Mar , 20 (166-73).

147

Hong D et al. Both hypokalaemic and normokalaemic periodic paralysis in different members of a single family with novel R1129Q mutation in SCN4A gene.
J. Neurol. Neurosurg. Psychiatr., 2010 Jun , 81 (703-4).

148

Desaphy JF et al. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Br. J. Pharmacol., 2010 Jul , 160 (1521-33).

149

Hong D et al. Novel human pathological mutations. Gene symbol: SCN4A. Disease: Periodic paralysis.
Hum. Genet., 2010 Jan , 127 (113).

150

Jarecki BW et al. Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.
J. Clin. Invest., 2010 Jan , 120 (369-78).

151

Matthews E et al. Muscle channelopathies: does the predicted channel gating pore offer new treatment options for hypokalaemic periodic paralysis?
, 2010 Feb 1 , ().

152

Fu Y et al. Gating Behavior of Sodium Currents in Adult Mouse MuscleRecorded with an Improved Two-Electrode Voltage Clamp.
J. Physiol. (Lond.), 2010 Dec 6 , ().

153

Arnegard ME et al. Old gene duplication facilitates origin and diversification of an innovative communication system--twice.
Proc. Natl. Acad. Sci. U.S.A., 2010 Dec 21 , 107 (22172-7).

154

Ghelardini C et al. Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models.
Neuroscience, 2010 Aug 25 , 169 (863-73).

155

Lion-Francois L et al. Severe neonatal episodic laryngospasm due to de novo SCN4A mutations: a new treatable disorder.
Neurology, 2010 Aug 17 , 75 (641-5).

156

Sokolov S et al. Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations.
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