KChIP2

1

Nassal DM et al. Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role.
PLoS ONE, 2016 , 11 (e0146561).

2

Duarri A et al. Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner.
Cell. Mol. Life Sci., 2015 Sep , 72 (3387-99).

3

Perez-Cortes EJ et al. Modulation of the transient outward current (Ito) in rat cardiac myocytes and human Kv4.3 channels by mefloquine.
Toxicol. Appl. Pharmacol., 2015 Oct 15 , 288 (203-12).

4

Yu H et al. Effect of Tyrphostin AG879 on Kv4.2 and Kv4.3 potassium channels.
Br. J. Pharmacol., 2015 Mar 8 , ().

5

Turnow K et al. Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito.
Basic Res. Cardiol., 2015 Mar , 110 (5).

6

You T et al. Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.
Int. J. Mol. Med., 2015 Jul , 36 (309-15).

7

Männikkö R et al. Pharmacological and electrophysiological characterisation of hERG activator AZSMO-23.
Br. J. Pharmacol., 2015 Feb 12 , ().

8

Rudakova E et al. Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes.
Pflugers Arch., 2015 Feb , 467 (299-309).

9

Grubb S et al. Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2.
Am. J. Physiol. Heart Circ. Physiol., 2015 Aug 1 , 309 (H481-9).

10

Chae YJ et al. Raloxifene inhibits cloned Kv4.3 channels in an estrogen receptor-independent manner.
Pflugers Arch., 2015 Aug , 467 (1663-76).

11

Chiu SN et al. Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model.
J Am Heart Assoc, 2015 , 4 ().

12

Liu J et al. Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.
PLoS ONE, 2015 , 10 (e0133274).

13

Mirams GR et al. Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
J Pharmacol Toxicol Methods, 2014 Nov-Dec , 70 (246-54).

14

Shi S et al. Chronic N-Methyl-d-Aspartate Receptor Activation Induces Cardiac Electrical Remodeling and Increases Susceptibility to Ventricular Arrhythmias.
Pacing Clin Electrophysiol, 2014 May 30 , ().

15

Zhang H et al. Long‑term treatment of spontaneously hypertensive rats with losartan and molecular basis of modulating Ito of ventricular myocytes.
Mol Med Rep, 2014 May , 9 (1959-67).

16

López-Izquierdo A et al. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.
Am. J. Physiol. Heart Circ. Physiol., 2014 Mar 1 , 306 (H747-54).

17

Perrin MJ et al. Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death.
Circ Cardiovasc Genet, 2014 Dec , 7 (782-9).

18

Sato T et al. Type 2 diabetes induces subendocardium-predominant reduction in transient outward K+ current with downregulation of Kv4.2 and KChIP2.
Am. J. Physiol. Heart Circ. Physiol., 2014 Apr 1 , 306 (H1054-65).

19

Choudhury S et al. Antibodies against potassium channel interacting protein 2 induce necrosis in isolated rat cardiomyocytes.
J. Cell. Biochem., 2014 Apr , 115 (678-89).

20

Odagiri F et al. Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.
PLoS ONE, 2014 , 9 (e101838).

21

Wang Y et al. The beneficial effect of electro-acupuncture given at PC6 (Neiguan-point) by the increase in cardiac transient outward K+ current channel which depends on the gene and protein expressions in artificially induced myocardial ischemia rats.
Acupunct Electrother Res, 2014 , 39 (259-73).

22

Kurokawa S et al. Cardiomyocyte-derived mitochondrial superoxide causes myocardial electrical remodeling by downregulating potassium channels and related molecules.
Circ. J., 2014 , 78 (1950-9).

23

Tan XQ et al. Multi-walled carbon nanotubes impair Kv4.2/4.3 channel activities, delay membrane repolarization and induce bradyarrhythmias in the rat.
PLoS ONE, 2014 , 9 (e101545).

24

Elkins RC et al. Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment.
J Pharmacol Toxicol Methods, 2013 Jul-Aug , 68 (112-22).

25

Cordeiro JM et al. Developmental changes in expression and biophysics of ion channels in the canine ventricle.
J. Mol. Cell. Cardiol., 2013 Sep 10 , 64C (79-89).

26

Foeger NC et al. Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.
J. Physiol. (Lond.), 2013 Sep 1 , 591 (4149-66).

27

Speerschneider T et al. Development of Heart Failure is Independent of KChIP2 Expression.
J. Physiol. (Lond.), 2013 Oct 7 , ().

28

Wang HG et al. The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability.
J. Biol. Chem., 2013 May 10 , 288 (13258-68).

29

Olesen MS et al. A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation.
Cardiovasc. Res., 2013 Jun 1 , 98 (488-95).

30

Panguluri SK et al. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle.
Am. J. Physiol. Heart Circ. Physiol., 2013 Jun , 304 (H1651-61).

31

Cordeiro JM et al. Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.
J. Mol. Cell. Cardiol., 2013 Jul , 60 (36-46).

32

Radicke S et al. Accessory subunits alter the temperature sensitivity of Kv4.3 channel complexes.
J. Mol. Cell. Cardiol., 2013 Jan 3 , ().

33

Tong M et al. Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart.
Biol Rhythm Res, 2013 Aug , 44 (519-530).

34

Ambrosi CM et al. Gender differences in electrophysiological gene expression in failing and non-failing human hearts.
PLoS ONE, 2013 , 8 (e54635).

35

Panguluri SK et al. MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators.
PLoS ONE, 2013 , 8 (e60545).

36

Kaur K et al. TGF-β1, released by myofibroblasts, differentially regulates transcription and function of sodium and potassium channels in adult rat ventricular myocytes.
PLoS ONE, 2013 , 8 (e55391).

37

Ozgen N et al. Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.
Heart Rhythm, 2012 Nov , 9 (1865-72).

38

Schulte JS et al. CREB critically regulates action potential shape and duration in the adult mouse ventricle.
, 2012 Mar 16 , ().

39

Jeyaraj D et al. Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Nature, 2012 Mar 1 , 483 (96-9).

40

Hardziyenka M et al. Electrophysiologic remodeling of the left ventricle in pressure overload-induced right ventricular failure.
J. Am. Coll. Cardiol., 2012 Jun 12 , 59 (2193-202).

41

Gönczi M et al. Age-dependent changes in ion channel mRNA expression in canine cardiac tissues.
Gen. Physiol. Biophys., 2012 Jun , 31 (153-62).

42

Cotella D et al. N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.
Int. J. Biochem. Cell Biol., 2012 Jun , 44 (876-85).

43

Martin CA et al. Reduced Na(+) and higher K(+) channel expression and function contribute to right ventricular origin of arrhythmias in Scn5a+/- mice.
Open Biol, 2012 Jun , 2 (120072).

44

Yan Q et al. Evolution of CpG island promoter function underlies changes in KChIP2 potassium channel subunit gene expression in mammalian heart.
Proc. Natl. Acad. Sci. U.S.A., 2012 Jan 31 , 109 (1601-6).

45

Witzel K et al. Hippocampal A-type current and Kv4.2 channel modulation by the sulfonylurea compound NS5806.
Neuropharmacology, 2012 Dec , 63 (1389-403).

46

Abd Allah ES et al. Postnatal development of transmural gradients in expression of ion channels and Ca(2+)-handling proteins in the ventricle.
, 2012 Apr 17 , ().

47

Suzuki T et al. Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.
PLoS ONE, 2012 , 7 (e35353).

48

Grubb S et al. Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure.
Front Physiol, 2012 , 3 (118).

49

Nakajima T et al. KCNE3 T4A as the genetic basis of Brugada-pattern electrocardiogram.
Circ. J., 2012 , 76 (2763-72).

50

Hovind LJ et al. The "structurally minimal" isoform KChIP2d modulates recovery of K(v)4.3 N-terminal deletion mutant Δ2-39.
Channels (Austin), 2011 May-Jun , 5 (225-7).

51

Panama BK et al. Nuclear factor kappaB downregulates the transient outward potassium current I(to,f) through control of KChIP2 expression.
Circ. Res., 2011 Mar 4 , 108 (537-43).

52

Bignolais O et al. Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block.
, 2011 Jul 22 , ().

53

Hovind LJ et al. K(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.
Channels (Austin), 2011 Jan 1 , 5 (43-55).

54

Giudicessi JR et al. Transient Outward Current (Ito) Gain-of-Function Mutations in the KCND3-Encoded Kv4.3 Potassium Channel and Brugada Syndrome.
, 2011 Feb 21 , ().

55

Marshall GE et al. Remodelling of human atrial K(+) currents but not ion channel expression by chronic β-blockade.
, 2011 Dec 8 , ().

56

Davies MR et al. An In silico Canine Cardiac Midmyocardial Action Potential Duration Model as a Tool for Early Drug Safety Assessment.
, 2011 Dec 23 , ().

57

Frolov RV et al. Inhibition of HERG potassium channels by celecoxib and its mechanism.
PLoS ONE, 2011 , 6 (e26344).

58

Wen HZ et al. Semaphorin 3A attenuates electrical remodeling at infarct border zones in rats after myocardial infarction.
Tohoku J. Exp. Med., 2011 , 225 (51-7).

59

Wagner M et al. Open channel block of the fast transient outward K(+) current by primaquine and chloroquine in rat left ventricular cardiomyocytes.
, 2010 Sep 2 , ().

60

Liu W et al. High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins.
J. Mol. Cell. Cardiol., 2010 Sep , 49 (438-48).

61

Foeger NC et al. Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexes.
J. Biol. Chem., 2010 Oct 22 , 285 (33413-22).

62

Norris AJ et al. Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.
J. Neurosci., 2010 Oct 13 , 30 (13644-55).

63

Kuryshev YA et al. Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels.
J. Cardiovasc. Pharmacol., 2010 Oct , 56 (420-30).

64

Gaborit N et al. Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts.
, 2010 Jun 21 , ().

65

Cotella D et al. Impaired glycosylation blocks DPP10 cell surface expression and alters the electrophysiology of Ito channel complex.
Pflugers Arch., 2010 Jun , 460 (87-97).

66

Levy DI et al. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
J. Physiol. (Lond.), 2010 Jul 15 , 588 (2657-68).

67

Ozgen N et al. Determinants of CREB degradation and KChIP2 gene transcription in cardiac memory.
Heart Rhythm, 2010 Jul , 7 (964-70).

68

Tozakidou M et al. Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle.
J. Mol. Cell. Cardiol., 2010 Jan , 48 (140-51).

69

Calloe K et al. Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.
J. Mol. Cell. Cardiol., 2010 Jan , 48 (191-200).

70

Dabrowska J et al. Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
Neuroscience, 2010 Dec 15 , 171 (721-33).

71

Oh S et al. Remodeling of ion channel expression in patients with chronic atrial fibrillation and mitral valvular heart disease.
Korean J. Intern. Med., 2010 Dec , 25 (377-85).

72

Macías A et al. Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials.
J. Mol. Cell. Cardiol., 2010 Dec , 49 (984-92).

73

Medei E et al. Chronic treatment with anabolic steroids induces ventricular repolarization disturbances: cellular, ionic and molecular mechanism.
J. Mol. Cell. Cardiol., 2010 Aug , 49 (165-75).

74

Lundby A et al. Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.
Br. J. Pharmacol., 2010 Aug , 160 (2028-44).

75

Xu X et al. Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.
PLoS ONE, 2010 , 5 (e10140).

76

Thomsen MB et al. Transcriptional and electrophysiological consequences of KChIP2-mediated regulation of CaV1.2.
Channels (Austin), 2009 Sep-Oct , 3 (308-10).

77

Soltysinska E et al. Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.
Pflugers Arch., 2009 Nov , 459 (11-23).

78

Stones R et al. The role of transient outward K+ current in electrical remodelling induced by voluntary exercise in female rat hearts.
Basic Res. Cardiol., 2009 Nov , 104 (643-52).

79

Maguy A et al. Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure.
Circ. Res., 2009 May 8 , 104 (1113-22).

80

Flowerdew SE et al. A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels.
Biochem. J., 2009 Mar 15 , 418 (529-40).

81

Gassanov N et al. Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.
J. Physiol. (Lond.), 2009 Mar 15 , 587 (1319-29).

82

Thomsen MB et al. Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration.
, 2009 Mar , 6 (370-7).

83

Seikel E et al. Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.
Biochemistry, 2009 Jun 23 , 48 (5721-30).

84

Thomsen MB et al. Accessory subunit KChIP2 modulates the cardiac L-type calcium current.
Circ. Res., 2009 Jun 19 , 104 (1382-9).

85

Radicke S et al. The transmembrane beta-subunits KCNE1, KCNE2, and DPP6 modify pharmacological effects of the antiarrhythmic agent tedisamil on the transient outward current Ito.
Naunyn Schmiedebergs Arch. Pharmacol., 2009 Jun , 379 (617-26).

86

Wagner S et al. Ca/calmodulin kinase II differentially modulates potassium currents.
Circ Arrhythm Electrophysiol, 2009 Jun , 2 (285-94).

87

Greener ID et al. Ion channel transcript expression at the rabbit atrioventricular conduction axis.
Circ Arrhythm Electrophysiol, 2009 Jun , 2 (305-15).

88

Tan XQ et al. [Atrial myocytes KChIP2 mRNA expression in rheumatic heart disease patients with atrial fibrillation]
Zhonghua Xin Xue Guan Bing Za Zhi, 2009 Jun , 37 (509-13).

89

DeSimone CV et al. S3b amino acid substitutions and ancillary subunits alter the affinity of Heteropoda venatoria toxin 2 for Kv4.3.
Mol. Pharmacol., 2009 Jul , 76 (125-33).

90

Wagner M et al. Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.
, 2009 Dec 2 , ().

91

Saito T et al. Estrogen contributes to gender differences in mouse ventricular repolarization.
Circ. Res., 2009 Aug 14 , 105 (343-52).

92

Lee L et al. Functional roles of EF-hands in human potassium channel-interacting protein 2.2.
Protein Pept. Lett., 2009 , 16 (1081-7).

93

Xiao L et al. Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes.
Circ. Res., 2008 Sep 26 , 103 (733-42).

94

Deschênes I et al. Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents.
J. Mol. Cell. Cardiol., 2008 Sep , 45 (336-46).

95

Monaghan MM et al. Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy.
Neuroscience, 2008 Oct 15 , 156 (550-62).

96

Bai J et al. Chemical sympathetic denervation, suppression of myocardial transient outward potassium current, and ventricular fibrillation in the rat.
Can. J. Physiol. Pharmacol., 2008 Oct , 86 (700-9).

97

Schwoerer AP et al. Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
J. Mol. Cell. Cardiol., 2008 Nov , 45 (633-41).

98

Marionneau C et al. Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.
Circ. Res., 2008 Jun 6 , 102 (1406-15).

99

Marionneau C et al. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.
J. Mol. Cell. Cardiol., 2008 Jun , 44 (1002-15).

100

Liu WJ et al. Co-expression of KCNE2 and KChIP2c modulates the electrophysiological properties of Kv4.2 current in COS-7 cells.
Acta Pharmacol. Sin., 2008 Jun , 29 (653-60).

101

Radicke S et al. Effects of MiRP1 and DPP6 beta-subunits on the blockade induced by flecainide of Kv4.3/KChIP2 channels.
Br. J. Pharmacol., 2008 Jun , 154 (774-86).

102

Li X et al. Regulation of Kv4 channel expression in failing rat heart by the thioredoxin system.
Am. J. Physiol. Heart Circ. Physiol., 2008 Jul , 295 (H416-24).

103

Niwa N et al. Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.
J. Mol. Cell. Cardiol., 2008 Jan , 44 (95-104).

104

Barghaan J et al. Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.
Biophys. J., 2008 Feb 15 , 94 (1276-94).

105

Stoll M et al. Spatial heterogeneity of myocardial perfusion predicts local potassium channel expression and action potential duration.
Cardiovasc. Res., 2008 Feb 1 , 77 (489-96).

106

Jerng HH et al. Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.
J. Biol. Chem., 2008 Dec 19 , 283 (36046-59).

107

Ren C et al. Nerve sprouting suppresses myocardial I(to) and I(K1) channels and increases severity to ventricular fibrillation in rat.
, 2008 Dec 15 , 144 (22-9).

108

Lu Z et al. Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity.
Circ. Res., 2008 Aug 1 , 103 (269-78).

109

Abbott GW et al. Impact of ancillary subunits on ventricular repolarization.
, 2007 Nov-Dec , 40 (S42-6).

110

Amadi CC et al. Regulation of Kv4.3 closed state inactivation and recovery by extracellular potassium and intracellular KChIP2b.
Channels (Austin), 2007 Jul-Aug , 1 (305-14).

111

Yamakawa T et al. Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating.
Biochemistry, 2007 Sep 25 , 46 (10942-9).

112

Rajagopal S et al. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit.
Protein Sci., 2007 Sep , 16 (2056-64).

113

Schultz JH et al. Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle.
Pflugers Arch., 2007 May , 454 (195-207).

114

Teutsch C et al. Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection.
Cardiovasc. Res., 2007 Mar 1 , 73 (739-49).

115

Gaborit N et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
J. Physiol. (Lond.), 2007 Jul 15 , 582 (675-93).

116

Liu XS et al. Electrical remodeling in a canine model of ischemic cardiomyopathy.
Am. J. Physiol. Heart Circ. Physiol., 2007 Jan , 292 (H560-71).

117

Lengyel C et al. Diabetes mellitus attenuates the repolarization reserve in mammalian heart.
Cardiovasc. Res., 2007 Feb 1 , 73 (512-20).

118

Goltz D et al. Diminished Kv4.2/3 but not KChIP2 levels reduce the cardiac transient outward K+ current in spontaneously hypertensive rats.
Cardiovasc. Res., 2007 Apr 1 , 74 (85-95).

119

Dun W et al. Ionic mechanisms underlying region-specific remodeling of rabbit atrial action potentials caused by intermittent burst stimulation.
, 2007 Apr , 4 (499-507).

120

Wirth KJ et al. In vitro and in vivo effects of the atrial selective antiarrhythmic compound AVE1231.
J. Cardiovasc. Pharmacol., 2007 Apr , 49 (197-206).

121

Han W et al. C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2.
J. Biol. Chem., 2006 Sep 15 , 281 (27134-44).

122

Radicke S et al. Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts.
Cardiovasc. Res., 2006 Sep 1 , 71 (695-703).

123

Ohya S [Molecular pharmacological studies on potassium channels and their regulatory molecules]
Yakugaku Zasshi, 2006 Oct , 126 (945-53).

124

Li HL et al. DPP10 is an inactivation modulatory protein of Kv4.3 and Kv1.4.
Am. J. Physiol., Cell Physiol., 2006 Nov , 291 (C966-76).

125

Rossow CF et al. Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart.
Circ. Res., 2006 May 26 , 98 (1306-13).

126

Chen CP et al. Effects of metal-binding properties of human Kv channel-interacting proteins on their molecular structure and binding with Kv4.2 channel.
Protein J., 2006 Jul , 25 (345-51).

127

Bett GC et al. KChIP2b modulates the affinity and use-dependent block of Kv4.3 by nifedipine.
Biochem. Biophys. Res. Commun., 2006 Feb 24 , 340 (1167-77).

128

Gong N et al. Calcineurin increases cardiac transient outward K+ currents via transcriptional up-regulation of Kv4.2 channel subunits.
J. Biol. Chem., 2006 Dec 15 , 281 (38498-506).

129

Flaim SN et al. Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes.
Am. J. Physiol. Heart Circ. Physiol., 2006 Dec , 291 (H2617-29).

130

Lundby A et al. KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel.
Biochem. Biophys. Res. Commun., 2006 Aug 4 , 346 (958-67).

131

Iida H et al. Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells.
Br. J. Pharmacol., 2005 Sep , 146 (49-59).

132

Callsen B et al. Contribution of N- and C-terminal Kv4.2 channel domains to KChIP interaction [corrected]
J. Physiol. (Lond.), 2005 Oct 15 , 568 (397-412).

133

Solth A et al. Inhibition of Kv4.3/KChIP2.2 channels by bupivacaine and its modulation by the pore mutation Kv4.3V401I.
Anesthesiology, 2005 Oct , 103 (796-804).

134

Patel SP et al. Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.
J. Physiol. (Lond.), 2005 Nov 15 , 569 (7-39).

135

Patberg KW et al. The cAMP response element binding protein modulates expression of the transient outward current: implications for cardiac memory.
Cardiovasc. Res., 2005 Nov 1 , 68 (259-67).

136

Pruunsild P et al. Structure, alternative splicing, and expression of the human and mouse KCNIP gene family.
Genomics, 2005 Nov , 86 (581-93).

137

Cotella D et al. Silencing the cardiac potassium channel Kv4.3 by RNA interference in a CHO expression system.
Biochem. Biophys. Res. Commun., 2005 May 6 , 330 (555-60).

138

Rose J et al. Molecular correlates of altered expression of potassium currents in failing rabbit myocardium.
Am. J. Physiol. Heart Circ. Physiol., 2005 May , 288 (H2077-87).

139

Szentadrassy N et al. Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium.
Cardiovasc. Res., 2005 Mar 1 , 65 (851-60).

140

Radicke S et al. Expression and function of dipeptidyl-aminopeptidase-like protein 6 as a putative beta-subunit of human cardiac transient outward current encoded by Kv4.3.
J. Physiol. (Lond.), 2005 Jun 15 , 565 (751-6).

141

Akar FG et al. Molecular mechanisms underlying K+ current downregulation in canine tachycardia-induced heart failure.
Am. J. Physiol. Heart Circ. Physiol., 2005 Jun , 288 (H2887-96).

142

Li H et al. KChIP2 modulates the cell surface expression of Kv 1.5-encoded K(+) channels.
J. Mol. Cell. Cardiol., 2005 Jul , 39 (121-32).

143

Persson F et al. Blocking characteristics of hKv1.5 and hKv4.3/hKChIP2.2 after administration of the novel antiarrhythmic compound AZD7009.
J. Cardiovasc. Pharmacol., 2005 Jul , 46 (7-17).

144

Ramakers C et al. Molecular and electrical characterization of the canine cardiac ventricular septum.
J. Mol. Cell. Cardiol., 2005 Jan , 38 (153-61).

145

Suzuki T et al. Differential expression of Kv4 pore-forming and KChIP auxiliary subunits in rat uterus during pregnancy.
Am. J. Physiol. Endocrinol. Metab., 2005 Feb , 288 (E335-41).

146

Guo W et al. Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction.
Circ. Res., 2005 Dec 9 , 97 (1342-50).

147

Szabó G et al. Asymmetrical distribution of ion channels in canine and human left-ventricular wall: epicardium versus midmyocardium.
Pflugers Arch., 2005 Aug , 450 (307-16).

148

Schultz JH et al. Kv4.2 and KChIP2 transcription in individual cardiomyocytes from the rat left ventricular free wall.
J. Mol. Cell. Cardiol., 2005 Aug , 39 (269-75).

149

Strassle BW et al. Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells.
J. Comp. Neurol., 2005 Apr 4 , 484 (144-55).

150

Baltaev R et al. Regulation of cardiac shal-related potassium channel Kv 4.3 by serum- and glucocorticoid-inducible kinase isoforms in Xenopus oocytes.
Pflugers Arch., 2005 Apr , 450 (26-33).

151

Rhodes KJ et al. KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.
J. Neurosci., 2004 Sep 8 , 24 (7903-15).

152

Xiong H et al. Differential distribution of KChIPs mRNAs in adult mouse brain.
Brain Res. Mol. Brain Res., 2004 Sep 28 , 128 (103-11).

153

Wakisaka Y et al. Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure.
Cardiovasc. Res., 2004 Sep 1 , 63 (689-99).

154

Gögelein H et al. Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels.
Naunyn Schmiedebergs Arch. Pharmacol., 2004 Sep , 370 (183-92).

155

Buxbaum JD A role for calsenilin and related proteins in multiple aspects of neuronal function.
Biochem. Biophys. Res. Commun., 2004 Oct 1 , 322 (1140-4).

156

Doronin SV et al. Angiotensin receptor type 1 forms a complex with the transient outward potassium channel Kv4.3 and regulates its gating properties and intracellular localization.
J. Biol. Chem., 2004 Nov 12 , 279 (48231-7).

157

Patel SP et al. Regulation of Kv4.3 voltage-dependent gating kinetics by KChIP2 isoforms.
J. Physiol. (Lond.), 2004 May 15 , 557 (19-41).

158

Wang S et al. Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence.
J. Physiol. (Lond.), 2004 Jun 15 , 557 (705-17).

159

Decher N et al. Novel KChIP2 isoforms increase functional diversity of transient outward potassium currents.
J. Physiol. (Lond.), 2004 Jun 15 , 557 (761-72).

160

Gebauer M et al. N-type inactivation features of Kv4.2 channel gating.
Biophys. J., 2004 Jan , 86 (210-23).

161

Kim LA et al. Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution.
Neuron, 2004 Feb 19 , 41 (513-9).

162

Kim LA et al. Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2.
J. Biol. Chem., 2004 Feb 13 , 279 (5549-54).

163

Zicha S et al. Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts.
J. Physiol. (Lond.), 2004 Dec 15 , 561 (735-48).

164

Pourrier M et al. The Kv4.2 N-terminal restores fast inactivation and confers KChlP2 modulatory effects on N-terminal-deleted Kv1.4 channels.
Pflugers Arch., 2004 Dec , 449 (235-47).

165

Friederich P et al. Interaction of ropivacaine with cloned cardiac Kv4.3/KChIP2.2 complexes.
Anesthesiology, 2004 Dec , 101 (1347-56).

166

Plotnikov AN et al. Cardiac memory evolves with age in association with development of the transient outward current.
Circulation, 2004 Aug 3 , 110 (489-95).

167

Lin YL et al. Protein-protein interactions of KChIP proteins and Kv4.2.
Biochem. Biophys. Res. Commun., 2004 Aug 27 , 321 (606-10).

168

Brunet S et al. Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles.
J. Physiol. (Lond.), 2004 Aug 15 , 559 (103-20).

169

Kobayashi T et al. Contribution of KChIP2 to the developmental increase in transient outward current of rat cardiomyocytes.
J. Mol. Cell. Cardiol., 2003 Sep , 35 (1073-82).

170

Wang Y et al. Differences in transient outward current properties between neonatal and adult human atrial myocytes.
J. Mol. Cell. Cardiol., 2003 Sep , 35 (1083-92).

171

Ren X et al. Effective association of Kv channel-interacting proteins with Kv4 channel is mediated with their unique core peptide.
J. Biol. Chem., 2003 Oct 31 , 278 (43564-70).

172

Rosati B et al. Concordant expression of KChIP2 mRNA, protein and transient outward current throughout the canine ventricle.
J. Physiol. (Lond.), 2003 May 1 , 548 (815-22).

173

Bosch RF et al. Molecular mechanisms of early electrical remodeling: transcriptional downregulation of ion channel subunits reduces I(Ca,L) and I(to) in rapid atrial pacing in rabbits.
J. Am. Coll. Cardiol., 2003 Mar 5 , 41 (858-69).

174

Lee SY et al. Adult alveolar epithelial cells express multiple subtypes of voltage-gated K+ channels that are located in apical membrane.
Am. J. Physiol., Cell Physiol., 2003 Jun , 284 (C1614-24).

175

Swynghedauw B et al. The long QT interval is not only inherited but is also linked to cardiac hypertrophy.
J. Mol. Med., 2003 Jun , 81 (336-45).

176

Hatano N et al. Dihydropyridine Ca2+ channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K+ channels expressed in HEK293 cells.
Br. J. Pharmacol., 2003 Jun , 139 (533-44).

177

Deschênes I et al. Modulation of Kv4.3 current by accessory subunits.
FEBS Lett., 2002 Sep 25 , 528 (183-8).

178

Patel SP et al. Elucidating KChIP effects on Kv4.3 inactivation and recovery kinetics with a minimal KChIP2 isoform.
J. Physiol. (Lond.), 2002 Nov 15 , 545 (5-11).

179

Guo W et al. Role of heteromultimers in the generation of myocardial transient outward K+ currents.
Circ. Res., 2002 Mar 22 , 90 (586-93).

180

Patel SP et al. Heterogeneous expression of KChIP2 isoforms in the ferret heart.
J. Physiol. (Lond.), 2002 Mar 15 , 539 (649-56).

181

Takimoto K et al. Palmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channels.
J. Biol. Chem., 2002 Jul 26 , 277 (26904-11).

182

Deschênes I et al. Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)?
Circulation, 2002 Jul 23 , 106 (423-9).

183

Wang S et al. Kinetic properties of Kv4.3 and their modulation by KChIP2b.
Biochem. Biophys. Res. Commun., 2002 Jul 12 , 295 (223-9).

184

Iwasa H et al. Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
J. Hum. Genet., 2002 , 47 (208-12).

185

Decher N et al. hKChIP2 is a functional modifier of hKv4.3 potassium channels: cloning and expression of a short hKChIP2 splice variant.
Cardiovasc. Res., 2001 Nov , 52 (255-64).

186

Rosati B et al. Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle.
J. Physiol. (Lond.), 2001 May 15 , 533 (119-25).

187

Bähring R et al. Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating.
J. Biol. Chem., 2001 Jun 29 , 276 (23888-94).

188

Kuo HC et al. A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia.
Cell, 2001 Dec 14 , 107 (801-13).