KChIP2
188 literature references associated to KChIP2
1
Nassal DM
et al.
Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role.
PLoS ONE,
2016
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2
Duarri A
et al.
Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner.
Cell. Mol. Life Sci.,
2015
Sep
, 72 (3387-99).
3
Perez-Cortes EJ
et al.
Modulation of the transient outward current (Ito) in rat cardiac myocytes and human Kv4.3 channels by mefloquine.
Toxicol. Appl. Pharmacol.,
2015
Oct
15
, 288 (203-12).
4
Yu H
et al.
Effect of Tyrphostin AG879 on Kv4.2 and Kv4.3 potassium channels.
Br. J. Pharmacol.,
2015
Mar
8
, ().
5
Turnow K
et al.
Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito.
Basic Res. Cardiol.,
2015
Mar
, 110 (5).
6
You T
et al.
Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.
Int. J. Mol. Med.,
2015
Jul
, 36 (309-15).
7
Männikkö R
et al.
Pharmacological and electrophysiological characterisation of hERG activator AZSMO-23.
Br. J. Pharmacol.,
2015
Feb
12
, ().
8
Rudakova E
et al.
Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes.
Pflugers Arch.,
2015
Feb
, 467 (299-309).
9
Grubb S
et al.
Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2.
Am. J. Physiol. Heart Circ. Physiol.,
2015
Aug
1
, 309 (H481-9).
10
Chae YJ
et al.
Raloxifene inhibits cloned Kv4.3 channels in an estrogen receptor-independent manner.
Pflugers Arch.,
2015
Aug
, 467 (1663-76).
11
Liu J
et al.
Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.
PLoS ONE,
2015
, 10 (e0133274).
12
Chiu SN
et al.
Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model.
J Am Heart Assoc,
2015
, 4 ().
13
Mirams GR
et al.
Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
J Pharmacol Toxicol Methods,
2014 Nov-Dec
, 70 (246-54).
14
Shi S
et al.
Chronic N-Methyl-d-Aspartate Receptor Activation Induces Cardiac Electrical Remodeling and Increases Susceptibility to Ventricular Arrhythmias.
Pacing Clin Electrophysiol,
2014
May
30
, ().
15
Zhang H
et al.
Long‑term treatment of spontaneously hypertensive rats with losartan and molecular basis of modulating Ito of ventricular myocytes.
Mol Med Rep,
2014
May
, 9 (1959-67).
16
López-Izquierdo A
et al.
The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.
Am. J. Physiol. Heart Circ. Physiol.,
2014
Mar
1
, 306 (H747-54).
17
Perrin MJ
et al.
Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death.
Circ Cardiovasc Genet,
2014
Dec
, 7 (782-9).
18
Sato T
et al.
Type 2 diabetes induces subendocardium-predominant reduction in transient outward K+ current with downregulation of Kv4.2 and KChIP2.
Am. J. Physiol. Heart Circ. Physiol.,
2014
Apr
1
, 306 (H1054-65).
19
Choudhury S
et al.
Antibodies against potassium channel interacting protein 2 induce necrosis in isolated rat cardiomyocytes.
J. Cell. Biochem.,
2014
Apr
, 115 (678-89).
20
Tan XQ
et al.
Multi-walled carbon nanotubes impair Kv4.2/4.3 channel activities, delay membrane repolarization and induce bradyarrhythmias in the rat.
PLoS ONE,
2014
, 9 (e101545).
21
Kurokawa S
et al.
Cardiomyocyte-derived mitochondrial superoxide causes myocardial electrical remodeling by downregulating potassium channels and related molecules.
Circ. J.,
2014
, 78 (1950-9).
22
Wang Y
et al.
The beneficial effect of electro-acupuncture given at PC6 (Neiguan-point) by the increase in cardiac transient outward K+ current channel which depends on the gene and protein expressions in artificially induced myocardial ischemia rats.
Acupunct Electrother Res,
2014
, 39 (259-73).
23
Odagiri F
et al.
Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.
PLoS ONE,
2014
, 9 (e101838).
24
Elkins RC
et al.
Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment.
J Pharmacol Toxicol Methods,
2013 Jul-Aug
, 68 (112-22).
25
Cordeiro JM
et al.
Developmental changes in expression and biophysics of ion channels in the canine ventricle.
J. Mol. Cell. Cardiol.,
2013
Sep
10
, 64C (79-89).
26
Foeger NC
et al.
Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.
J. Physiol. (Lond.),
2013
Sep
1
, 591 (4149-66).
27
Speerschneider T
et al.
Development of Heart Failure is Independent of KChIP2 Expression.
J. Physiol. (Lond.),
2013
Oct
7
, ().
28
Wang HG
et al.
The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability.
J. Biol. Chem.,
2013
May
10
, 288 (13258-68).
29
Olesen MS
et al.
A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation.
Cardiovasc. Res.,
2013
Jun
1
, 98 (488-95).
30
Panguluri SK
et al.
Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle.
Am. J. Physiol. Heart Circ. Physiol.,
2013
Jun
, 304 (H1651-61).
31
Cordeiro JM
et al.
Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.
J. Mol. Cell. Cardiol.,
2013
Jul
, 60 (36-46).
32
Radicke S
et al.
Accessory subunits alter the temperature sensitivity of Kv4.3 channel complexes.
J. Mol. Cell. Cardiol.,
2013
Jan
3
, ().
33
Tong M
et al.
Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart.
Biol Rhythm Res,
2013
Aug
, 44 (519-530).
34
Kaur K
et al.
TGF-β1, released by myofibroblasts, differentially regulates transcription and function of sodium and potassium channels in adult rat ventricular myocytes.
PLoS ONE,
2013
, 8 (e55391).
35
Panguluri SK
et al.
MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators.
PLoS ONE,
2013
, 8 (e60545).
36
Ambrosi CM
et al.
Gender differences in electrophysiological gene expression in failing and non-failing human hearts.
PLoS ONE,
2013
, 8 (e54635).
37
Ozgen N
et al.
Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.
Heart Rhythm,
2012
Nov
, 9 (1865-72).
38
Schulte JS
et al.
CREB critically regulates action potential shape and duration in the adult mouse ventricle.
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2012
Mar
16
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39
Jeyaraj D
et al.
Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Nature,
2012
Mar
1
, 483 (96-9).
40
Hardziyenka M
et al.
Electrophysiologic remodeling of the left ventricle in pressure overload-induced right ventricular failure.
J. Am. Coll. Cardiol.,
2012
Jun
12
, 59 (2193-202).
41
Martin CA
et al.
Reduced Na(+) and higher K(+) channel expression and function contribute to right ventricular origin of arrhythmias in Scn5a+/- mice.
Open Biol,
2012
Jun
, 2 (120072).
42
Gönczi M
et al.
Age-dependent changes in ion channel mRNA expression in canine cardiac tissues.
Gen. Physiol. Biophys.,
2012
Jun
, 31 (153-62).
43
Cotella D
et al.
N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.
Int. J. Biochem. Cell Biol.,
2012
Jun
, 44 (876-85).
44
Yan Q
et al.
Evolution of CpG island promoter function underlies changes in KChIP2 potassium channel subunit gene expression in mammalian heart.
Proc. Natl. Acad. Sci. U.S.A.,
2012
Jan
31
, 109 (1601-6).
45
Witzel K
et al.
Hippocampal A-type current and Kv4.2 channel modulation by the sulfonylurea compound NS5806.
Neuropharmacology,
2012
Dec
, 63 (1389-403).
46
Abd Allah ES
et al.
Postnatal development of transmural gradients in expression of ion channels and Ca(2+)-handling proteins in the ventricle.
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2012
Apr
17
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47
Grubb S
et al.
Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure.
Front Physiol,
2012
, 3 (118).
48
Suzuki T
et al.
Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.
PLoS ONE,
2012
, 7 (e35353).
49
Nakajima T
et al.
KCNE3 T4A as the genetic basis of Brugada-pattern electrocardiogram.
Circ. J.,
2012
, 76 (2763-72).
50
Hovind LJ
et al.
The "structurally minimal" isoform KChIP2d modulates recovery of K(v)4.3 N-terminal deletion mutant Δ2-39.
Channels (Austin),
2011 May-Jun
, 5 (225-7).
51
Panama BK
et al.
Nuclear factor kappaB downregulates the transient outward potassium current I(to,f) through control of KChIP2 expression.
Circ. Res.,
2011
Mar
4
, 108 (537-43).
52
Bignolais O
et al.
Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block.
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2011
Jul
22
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53
Hovind LJ
et al.
K(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.
Channels (Austin),
2011
Jan
1
, 5 (43-55).
54
Giudicessi JR
et al.
Transient Outward Current (Ito) Gain-of-Function Mutations in the KCND3-Encoded Kv4.3 Potassium Channel and Brugada Syndrome.
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2011
Feb
21
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55
Marshall GE
et al.
Remodelling of human atrial K(+) currents but not ion channel expression by chronic β-blockade.
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2011
Dec
8
, ().
56
Davies MR
et al.
An In silico Canine Cardiac Midmyocardial Action Potential Duration Model as a Tool for Early Drug Safety Assessment.
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2011
Dec
23
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57
Wen HZ
et al.
Semaphorin 3A attenuates electrical remodeling at infarct border zones in rats after myocardial infarction.
Tohoku J. Exp. Med.,
2011
, 225 (51-7).
58
Frolov RV
et al.
Inhibition of HERG potassium channels by celecoxib and its mechanism.
PLoS ONE,
2011
, 6 (e26344).
59
Wagner M
et al.
Open channel block of the fast transient outward K(+) current by primaquine and chloroquine in rat left ventricular cardiomyocytes.
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2010
Sep
2
, ().
60
Liu W
et al.
High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins.
J. Mol. Cell. Cardiol.,
2010
Sep
, 49 (438-48).
61
Foeger NC
et al.
Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexes.
J. Biol. Chem.,
2010
Oct
22
, 285 (33413-22).
62
Norris AJ
et al.
Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.
J. Neurosci.,
2010
Oct
13
, 30 (13644-55).
63
Kuryshev YA
et al.
Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels.
J. Cardiovasc. Pharmacol.,
2010
Oct
, 56 (420-30).
64
Gaborit N
et al.
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts.
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2010
Jun
21
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65
Cotella D
et al.
Impaired glycosylation blocks DPP10 cell surface expression and alters the electrophysiology of Ito channel complex.
Pflugers Arch.,
2010
Jun
, 460 (87-97).
66
Levy DI
et al.
The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
J. Physiol. (Lond.),
2010
Jul
15
, 588 (2657-68).
67
Ozgen N
et al.
Determinants of CREB degradation and KChIP2 gene transcription in cardiac memory.
Heart Rhythm,
2010
Jul
, 7 (964-70).
68
Calloe K
et al.
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.
J. Mol. Cell. Cardiol.,
2010
Jan
, 48 (191-200).
69
Tozakidou M
et al.
Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle.
J. Mol. Cell. Cardiol.,
2010
Jan
, 48 (140-51).
70
Dabrowska J
et al.
Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
Neuroscience,
2010
Dec
15
, 171 (721-33).
71
Oh S
et al.
Remodeling of ion channel expression in patients with chronic atrial fibrillation and mitral valvular heart disease.
Korean J. Intern. Med.,
2010
Dec
, 25 (377-85).
72
Macías A
et al.
Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials.
J. Mol. Cell. Cardiol.,
2010
Dec
, 49 (984-92).
73
Lundby A
et al.
Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.
Br. J. Pharmacol.,
2010
Aug
, 160 (2028-44).
74
Medei E
et al.
Chronic treatment with anabolic steroids induces ventricular repolarization disturbances: cellular, ionic and molecular mechanism.
J. Mol. Cell. Cardiol.,
2010
Aug
, 49 (165-75).
75
Xu X
et al.
Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.
PLoS ONE,
2010
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76
Thomsen MB
et al.
Transcriptional and electrophysiological consequences of KChIP2-mediated regulation of CaV1.2.
Channels (Austin),
2009 Sep-Oct
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77
Soltysinska E
et al.
Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.
Pflugers Arch.,
2009
Nov
, 459 (11-23).
78
Stones R
et al.
The role of transient outward K+ current in electrical remodelling induced by voluntary exercise in female rat hearts.
Basic Res. Cardiol.,
2009
Nov
, 104 (643-52).
79
Maguy A
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Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure.
Circ. Res.,
2009
May
8
, 104 (1113-22).
80
Gassanov N
et al.
Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.
J. Physiol. (Lond.),
2009
Mar
15
, 587 (1319-29).
81
Flowerdew SE
et al.
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels.
Biochem. J.,
2009
Mar
15
, 418 (529-40).
82
Thomsen MB
et al.
Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration.
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2009
Mar
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83
Seikel E
et al.
Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.
Biochemistry,
2009
Jun
23
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84
Thomsen MB
et al.
Accessory subunit KChIP2 modulates the cardiac L-type calcium current.
Circ. Res.,
2009
Jun
19
, 104 (1382-9).
85
Radicke S
et al.
The transmembrane beta-subunits KCNE1, KCNE2, and DPP6 modify pharmacological effects of the antiarrhythmic agent tedisamil on the transient outward current Ito.
Naunyn Schmiedebergs Arch. Pharmacol.,
2009
Jun
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86
Greener ID
et al.
Ion channel transcript expression at the rabbit atrioventricular conduction axis.
Circ Arrhythm Electrophysiol,
2009
Jun
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87
Wagner S
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Ca/calmodulin kinase II differentially modulates potassium currents.
Circ Arrhythm Electrophysiol,
2009
Jun
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88
Tan XQ
et al.
[Atrial myocytes KChIP2 mRNA expression in rheumatic heart disease patients with atrial fibrillation]
Zhonghua Xin Xue Guan Bing Za Zhi,
2009
Jun
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89
DeSimone CV
et al.
S3b amino acid substitutions and ancillary subunits alter the affinity of Heteropoda venatoria toxin 2 for Kv4.3.
Mol. Pharmacol.,
2009
Jul
, 76 (125-33).
90
Wagner M
et al.
Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.
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2009
Dec
2
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91
Saito T
et al.
Estrogen contributes to gender differences in mouse ventricular repolarization.
Circ. Res.,
2009
Aug
14
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92
Lee L
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Functional roles of EF-hands in human potassium channel-interacting protein 2.2.
Protein Pept. Lett.,
2009
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93
Xiao L
et al.
Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes.
Circ. Res.,
2008
Sep
26
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94
Deschênes I
et al.
Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents.
J. Mol. Cell. Cardiol.,
2008
Sep
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95
Monaghan MM
et al.
Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy.
Neuroscience,
2008
Oct
15
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96
Bai J
et al.
Chemical sympathetic denervation, suppression of myocardial transient outward potassium current, and ventricular fibrillation in the rat.
Can. J. Physiol. Pharmacol.,
2008
Oct
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97
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Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
J. Mol. Cell. Cardiol.,
2008
Nov
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98
Marionneau C
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Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.
Circ. Res.,
2008
Jun
6
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99
Marionneau C
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PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.
J. Mol. Cell. Cardiol.,
2008
Jun
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100
Liu WJ
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Co-expression of KCNE2 and KChIP2c modulates the electrophysiological properties of Kv4.2 current in COS-7 cells.
Acta Pharmacol. Sin.,
2008
Jun
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101
Radicke S
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Effects of MiRP1 and DPP6 beta-subunits on the blockade induced by flecainide of Kv4.3/KChIP2 channels.
Br. J. Pharmacol.,
2008
Jun
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102
Li X
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Regulation of Kv4 channel expression in failing rat heart by the thioredoxin system.
Am. J. Physiol. Heart Circ. Physiol.,
2008
Jul
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103
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Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.
J. Mol. Cell. Cardiol.,
2008
Jan
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104
Barghaan J
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Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.
Biophys. J.,
2008
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105
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Spatial heterogeneity of myocardial perfusion predicts local potassium channel expression and action potential duration.
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106
Jerng HH
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Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.
J. Biol. Chem.,
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107
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Nerve sprouting suppresses myocardial I(to) and I(K1) channels and increases severity to ventricular fibrillation in rat.
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2008
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108
Lu Z
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Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity.
Circ. Res.,
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109
Abbott GW
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Impact of ancillary subunits on ventricular repolarization.
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Regulation of Kv4.3 closed state inactivation and recovery by extracellular potassium and intracellular KChIP2b.
Channels (Austin),
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111
Yamakawa T
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Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating.
Biochemistry,
2007
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112
Rajagopal S
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Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit.
Protein Sci.,
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113
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Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle.
Pflugers Arch.,
2007
May
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114
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Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection.
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115
Gaborit N
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Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
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2007
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116
Liu XS
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Electrical remodeling in a canine model of ischemic cardiomyopathy.
Am. J. Physiol. Heart Circ. Physiol.,
2007
Jan
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117
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Diabetes mellitus attenuates the repolarization reserve in mammalian heart.
Cardiovasc. Res.,
2007
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118
Goltz D
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Diminished Kv4.2/3 but not KChIP2 levels reduce the cardiac transient outward K+ current in spontaneously hypertensive rats.
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2007
Apr
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119
Dun W
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Ionic mechanisms underlying region-specific remodeling of rabbit atrial action potentials caused by intermittent burst stimulation.
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2007
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120
Wirth KJ
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In vitro and in vivo effects of the atrial selective antiarrhythmic compound AVE1231.
J. Cardiovasc. Pharmacol.,
2007
Apr
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121
Han W
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C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2.
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2006
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122
Radicke S
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Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts.
Cardiovasc. Res.,
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Ohya S
[Molecular pharmacological studies on potassium channels and their regulatory molecules]
Yakugaku Zasshi,
2006
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Li HL
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DPP10 is an inactivation modulatory protein of Kv4.3 and Kv1.4.
Am. J. Physiol., Cell Physiol.,
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125
Rossow CF
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Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart.
Circ. Res.,
2006
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126
Chen CP
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Effects of metal-binding properties of human Kv channel-interacting proteins on their molecular structure and binding with Kv4.2 channel.
Protein J.,
2006
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127
Bett GC
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KChIP2b modulates the affinity and use-dependent block of Kv4.3 by nifedipine.
Biochem. Biophys. Res. Commun.,
2006
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128
Gong N
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Calcineurin increases cardiac transient outward K+ currents via transcriptional up-regulation of Kv4.2 channel subunits.
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2006
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