Nav1.1

1

Du Y et al. β1-Adrenergic blocker bisoprolol reverses down-regulated ion channels in sinoatrial node of heart failure rats.
J. Physiol. Biochem., 2016 Jun , 72 (293-302).

2

Kim KX et al. Maturation of NaV and KV Channel Topographies in the Auditory Nerve Spike Initiator before and after Developmental Onset of Hearing Function.
J. Neurosci., 2016 Feb 17 , 36 (2111-8).

3

Murenzi E et al. Evaluation of microtransplantation of rat brain neurolemma into Xenopus laevis oocytes as a technique to study the effect of neurotoxicants on endogenous voltage-sensitive ion channels.
Neurotoxicology, 2016 Apr 7 , ().

4

Wildburger NC et al. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain.
Mol. Cell Proteomics, 2015 May , 14 (1288-300).

5

Tsai MS et al. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development.
Neurobiol. Dis., 2015 May , 77 (35-48).

6

Kalume F et al. Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.
Neurobiol. Dis., 2015 May , 77 (141-54).

7

Mishra S et al. Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts.
J. Physiol. (Lond.), 2015 Mar 15 , 593 (1409-27).

8

Gazina EV et al. 'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour.
Hum. Mol. Genet., 2015 Mar 1 , 24 (1457-68).

9

Bechi G et al. Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum.
Neurobiol. Dis., 2015 Mar , 75 (100-14).

10

Torregrosa R et al. Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
Bioorg. Med. Chem., 2015 Jul 1 , 23 (3655-66).

11

Slowik D et al. Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference.
Biochim. Biophys. Acta, 2015 Jul , 1848 (1545-51).

12

Fukuoka T et al. De novo expression of Nav1.7 in injured putative proprioceptive afferents: Multiple tetrodotoxin-sensitive sodium channels are retained in the rat dorsal root after spinal nerve ligation.
Neuroscience, 2015 Jan 22 , 284 (693-706).

13

Rubinstein M et al. Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
Neurobiol. Dis., 2015 Jan , 73 (106-17).

14

Huang X et al. Age-dependent alterations of voltage-gated Na(+) channel isoforms in rat sinoatrial node.
Mech. Ageing Dev., 2015 Dec , 152 (80-90).

15

Crestey F et al. Identification and electrophysiological evaluation of 2-methylbenzamide derivatives as Nav1.1 modulators.
ACS Chem Neurosci, 2015 Aug 19 , 6 (1302-8).

16

Biet M et al. Prolongation of action potential duration and QT interval during epilepsy linked to increased contribution of neuronal sodium channels to cardiac late Na+ current: potential mechanism for sudden death in epilepsy.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (912-20).

17

Rubinstein M et al. Dissecting the phenotypes of Dravet syndrome by gene deletion.
Brain, 2015 Aug , 138 (2219-33).

18

Cardoso FC et al. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol. Pharmacol., 2015 Aug , 88 (291-303).

19

Guo F et al. Low-Mg(2+) treatment increases sensitivity of voltage-gated Na(+) channels to Ca(2+)/calmodulin-mediated modulation in cultured hippocampal neurons.
Am. J. Physiol., Cell Physiol., 2015 Apr 15 , 308 (C594-605).

20

Zhang C et al. 17β-Estradiol increases persistent Na(+) current and excitability of AVPV/PeN Kiss1 neurons in female mice.
Mol. Endocrinol., 2015 Apr , 29 (518-27).

21

Chen YJ et al. Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.
Mol. Neurobiol., 2015 , 51 (1263-70).

22

Camargos TS et al. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.
PLoS ONE, 2015 , 10 (e0128578).

23

Sun LH et al. MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion.
Mol Neurodegener, 2015 , 10 (36).

24

Nikolaidou T et al. Congestive Heart Failure Leads to Prolongation of the PR Interval and Atrioventricular Junction Enlargement and Ion Channel Remodelling in the Rabbit.
PLoS ONE, 2015 , 10 (e0141452).

25

Chen W et al. Tumor necrosis factor-α enhances voltage-gated Na⁺ currents in primary culture of mouse cortical neurons.
J Neuroinflammation, 2015 , 12 (126).

26

Yamanushi TT et al. Comparison of formaldehyde and methanol fixatives used in the detection of ion channel proteins in isolated rat ventricular myocytes by immunofluorescence labelling and confocal microscopy.
Folia Morphol. (Warsz), 2015 , 74 (258-61).

27

Hoffman-Zacharska D et al. From focal epilepsy to Dravet syndrome--Heterogeneity of the phenotype due to SCN1A mutations of the p.Arg1596 amino acid residue in the Nav1.1 subunit.
Neurol. Neurochir. Pol., 2015 , 49 (258-66).

28

Patel RR et al. Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.
PLoS ONE, 2015 , 10 (e0133485).

29

Green BR et al. Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity.
Future Med Chem, 2014 Oct , 6 (1677-98).

30

Dong ZF et al. Transcription of the human sodium channel SCN1A gene is repressed by a scaffolding protein RACK1.
Mol. Neurobiol., 2014 Oct , 50 (438-48).

31

Hedrich UB et al. Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human Na(V)1.1 mutation.
J. Neurosci., 2014 Nov 5 , 34 (14874-89).

32

McGlothlin JW et al. Parallel evolution of tetrodotoxin resistance in three voltage-gated sodium channel genes in the garter snake Thamnophis sirtalis.
Mol. Biol. Evol., 2014 Nov , 31 (2836-46).

33

Gilchrist J et al. Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents.
ACS Chem. Biol., 2014 May 16 , 9 (1204-12).

34

Dhamija R et al. Sleep abnormalities in children with Dravet syndrome.
Pediatr. Neurol., 2014 May , 50 (474-8).

35

Matalon D et al. Confirming an expanded spectrum of SCN2A mutations: a case series.
Epileptic Disord, 2014 Mar , 16 (13-8).

36

Bagnéris C et al. Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jun 10 , 111 (8428-33).

37

Zeng T et al. A novel variant in the 3' UTR of human SCN1A gene from a patient with Dravet syndrome decreases mRNA stability mediated by GAPDH's binding.
Hum. Genet., 2014 Jun , 133 (801-11).

38

Zeng Q et al. [Src family kinases affect the expression of Nav1.1 in spiral ganglion neurons].
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2014 Jun , 28 (789-92).

39

Tai C et al. Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jul 29 , 111 (E3139-48).

40

Kahlig KM et al. Ranolazine reduces neuronal excitability by interacting with inactivated States of brain sodium channels.
Mol. Pharmacol., 2014 Jan , 85 (162-74).

41

Baroni D et al. Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression.
Biol. Cell, 2014 Jan , 106 (13-29).

42

Gajewiak J et al. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.
Proc. Natl. Acad. Sci. U.S.A., 2014 Feb 18 , 111 (2758-63).

43

Muroi Y et al. Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough.
Lung, 2014 Feb , 192 (15-20).

44

Magdaleno-Méndez A et al. Ghrelin increases growth hormone production and functional expression of NaV1.1 and Na V1.2 channels in pituitary somatotropes.
Endocrine, 2014 Aug 24 , ().

45

Makinson CD et al. Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.
Neurobiol. Dis., 2014 Aug , 68 (16-25).

46

Weller CM et al. Two novel SCN1A mutations identified in families with familial hemiplegic migraine.
Cephalalgia, 2014 Apr 4 , ().

47

Chen W et al. Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique.
Sci Rep, 2014 , 4 (5404).

48

Kim DY et al. The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells.
Neurodegener Dis, 2014 , 13 (64-8).

49

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

50

Luo J et al. Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.
Toxins (Basel), 2014 , 6 (2177-93).

51

Sivagangabalan G et al. Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PLoS ONE, 2014 , 9 (e82179).

52

Abdelsayed M et al. Voltage-gated sodium channels: pharmaceutical targets via anticonvulsants to treat epileptic syndromes.
Channels (Austin), 2013 May-Jun , 7 (146-52).

53

Zhu L et al. Two recombinant α-like scorpion toxins from Mesobuthus eupeus with differential affinity toward insect and mammalian Na(+) channels.
Biochimie, 2013 Sep , 95 (1732-40).

54

Qiao X et al. Expression of sodium channel α subunits 1.1, 1.2 and 1.6 in rat hippocampus after kainic acid-induced epilepsy.
Epilepsy Res., 2013 Sep , 106 (17-28).

55

Xiao M et al. FGF14 localization and organization of the axon initial segment.
Mol. Cell. Neurosci., 2013 Sep , 56 (393-403).

56

Puthussery T et al. NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina.
J. Neurosci., 2013 Oct 9 , 33 (16045-59).

57

Cestèle S et al. Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects.
Proc. Natl. Acad. Sci. U.S.A., 2013 Oct 22 , 110 (17546-51).

58

Black JA et al. Noncanonical roles of voltage-gated sodium channels.
Neuron, 2013 Oct 16 , 80 (280-91).

59

Sandalon S et al. Functional and structural evaluation of lamotrigine treatment in rat models of acute and chronic ocular hypertension.
Exp. Eye Res., 2013 Oct , 115 (47-56).

60

Jiao J et al. Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons.
Hum. Mol. Genet., 2013 Nov 1 , 22 (4241-52).

61

Westenbroek RE et al. Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry.
J. Mol. Cell. Cardiol., 2013 Nov , 64 (69-78).

62

Oakley JC et al. Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.
J. Pharmacol. Exp. Ther., 2013 May , 345 (215-24).

63

Bender AC et al. Focal Scn1a knockdown induces cognitive impairment without seizures.
Neurobiol. Dis., 2013 Jun , 54 (297-307).

64

McCormack K et al. Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jul 16 , 110 (E2724-32).

65

Xu X et al. Abnormal changes in voltage-gated sodium channels Na(V)1.1, Na(V)1.2, Na(V)1.3, Na(V)1.6 and in calmodulin/calmodulin-dependent protein kinase II, within the brains of spontaneously epileptic rats and tremor rats.
Brain Res. Bull., 2013 Jul , 96 (1-9).

66

Purcell RH et al. Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice.
Psychopharmacology (Berl.), 2013 Jul , 228 (263-70).

67

Ramachandra R et al. NaV1.8 channels are expressed in large, as well as small, diameter sensory afferent neurons.
Channels (Austin), 2013 Jan 1 , 7 (34-7).

68

Dutton SB et al. Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility.
Neurobiol. Dis., 2013 Jan , 49 (211-20).

69

Ito S et al. Mouse with Nav1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment.
Neurobiol. Dis., 2013 Jan , 49 (29-40).

70

Ogiwara I et al. Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.
Hum. Mol. Genet., 2013 Dec 1 , 22 (4784-804).

71

Volkers L et al. Febrile temperatures unmask biophysical defects in Nav1.1 epilepsy mutations supportive of seizure initiation.
J. Gen. Physiol., 2013 Dec , 142 (641-53).

72

Dustrude ET et al. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
J. Biol. Chem., 2013 Aug 23 , 288 (24316-31).

73

Liu S et al. Altered PKA modulation in the Nav1.1 epilepsy variant I1656M.
J. Neurophysiol., 2013 Aug 14 , ().

74

Kaufmann SG et al. Distribution and function of sodium channel subtypes in human atrial myocardium.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (133-41).

75

Corbett BF et al. Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
J. Neurosci., 2013 Apr 17 , 33 (7020-6).

76

Kalume F et al. Sudden unexpected death in a mouse model of Dravet syndrome.
J. Clin. Invest., 2013 Apr 1 , 123 (1798-808).

77

Zhou X et al. Modulation of mononuclear phagocyte inflammatory response by liposome-encapsulated voltage gated sodium channel inhibitor ameliorates myocardial ischemia/reperfusion injury in rats.
PLoS ONE, 2013 , 8 (e74390).

78

Baraban SC et al. Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.
Nat Commun, 2013 , 4 (2410).

79

Cheah CS et al. Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome.
Proc. Natl. Acad. Sci. U.S.A., 2012 Sep 4 , 109 (14646-51).

80

Hodgdon KE et al. Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Neuroscience, 2012 Mar 29 , 206 (237-44).

81

Zaharenko AJ et al. Characterization of selectivity and pharmacophores of type 1 sea anemone toxins by screening seven Na(v) sodium channel isoforms.
Peptides, 2012 Mar , 34 (158-67).

82

Liu P et al. Modulation of neuronal sodium channels by the sea anemone peptide BDS-I.
J. Neurophysiol., 2012 Jun , 107 (3155-67).

83

Fukuoka T et al. Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation.
Pain, 2012 Jan , 153 (68-79).

84

Ding H et al. Alterations of gene expression of sodium channels in dorsal root ganglion neurons of estrogen receptor knockout (ERKO) mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Endocrine, 2012 Aug , 42 (118-24).

85

Verret L et al. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.
Cell, 2012 Apr 27 , 149 (708-21).

86

Hu F et al. 17β-Estradiol regulates the gene expression of voltage-gated sodium channels: role of estrogen receptor α and estrogen receptor β.
Endocrine, 2012 Apr , 41 (274-80).

87

Akiyama M et al. Dravet syndrome: a genetic epileptic disorder.
Acta Med. Okayama, 2012 , 66 (369-76).

88

Fletcher EV et al. Alternative splicing modulates inactivation of type 1 voltage-gated sodium channels by toggling an amino acid in the first S3-S4 linker.
J. Biol. Chem., 2011 Oct 21 , 286 (36700-8).

89

Byers MR et al. Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels.
Arch. Oral Biol., 2011 Nov , 56 (1199-220).

90

Wilson MJ et al. μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve.
Proc. Natl. Acad. Sci. U.S.A., 2011 Jun 21 , 108 (10302-7).

91

Fukuoka T et al. Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion.
Neurosci. Res., 2011 Jun , 70 (164-71).

92

Ho C et al. Single-cell analysis of sodium channel expression in dorsal root ganglion neurons.
Mol. Cell. Neurosci., 2011 Jan , 46 (159-66).

93

Baroni D et al. Molecular differential expression of voltage-gated sodium channel α and β subunit mRNAs in five different mammalian cell lines.
J. Bioenerg. Biomembr., 2011 Dec , 43 (729-38).

94

Wang W et al. Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury.
Anat Rec (Hoboken), 2011 Aug , 294 (1406-11).

95

Guerrini R et al. Dravet syndrome and SCN1A gene mutation related-epilepsies: cognitive impairment and its determinants.
Dev Med Child Neurol, 2011 Apr , 53 Suppl 2 (11-5).

96

Yamakawa K Molecular and cellular basis: insights from experimental models of Dravet syndrome.
Epilepsia, 2011 Apr , 52 Suppl 2 (70-1).

97

Fukuoka T et al. Laminae-specific distribution of alpha-subunits of voltage-gated sodium channels in the adult rat spinal cord.
Neuroscience, 2010 Sep 1 , 169 (994-1006).

98

Ren L et al. Effect of electroacupuncture on the expression of Nav1.1 in rat after acute cerebral ischemia.
Neurol. Res., 2010 Sep , 32 (763-9).

99

Arlier Z et al. Four novel SCN1A mutations in Turkish patients with severe myoclonic epilepsy of infancy (SMEI).
J. Child Neurol., 2010 Oct , 25 (1265-8).

100

Chen R et al. Electrical injury alters ion channel expression levels and electrophysiological properties in rabbit dorsal root ganglia neurons.
, 2010 Nov 10 , ().

101

Gao R et al. Expression of voltage-gated sodium channel alpha subunit in human ovarian cancer.
Oncol. Rep., 2010 May , 23 (1293-9).

102

Black JA et al. Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5.
Brain, 2010 Mar , 133 (835-46).

103

Catterall WA et al. NaV1.1 channels and epilepsy.
J. Physiol. (Lond.), 2010 Jun 1 , 588 (1849-59).

104

Desaphy JF et al. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Br. J. Pharmacol., 2010 Jul , 160 (1521-33).

105

Lampert A et al. Sodium channelopathies and pain.
Pflugers Arch., 2010 Jul , 460 (249-63).

106

Berendt FJ et al. Multi-site Phosphorylation of Voltage-Gated Sodium Channel alpha Subunits from Rat Brain.
, 2010 Feb 5 , ().

107

Mashimo T et al. A missense mutation of the gene encoding voltage-dependent sodium channel (Nav1.1) confers susceptibility to febrile seizures in rats.
J. Neurosci., 2010 Apr 21 , 30 (5744-53).

108

Persson AK et al. Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals.
Mol Pain, 2010 , 6 (84).

109

Gambardella A et al. Clinical spectrum of SCN1A mutations.
Epilepsia, 2009 May , 50 Suppl 5 (20-3).

110

Yamakawa K Molecular basis of severe myoclonic epilepsy in infancy.
Brain Dev., 2009 May , 31 (401-4).

111

Vahedi K et al. Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations.
Neurology, 2009 Mar 31 , 72 (1178-83).

112

Castro MJ et al. First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy.
Cephalalgia, 2009 Mar , 29 (308-13).

113

Rusconi R et al. A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies?
Hum. Mutat., 2009 Jul , 30 (E747-60).

114

Tan J et al. Human and rat Nav1.3 voltage-gated sodium channels differ in inactivation properties and sensitivity to the pyrethroid insecticide tefluthrin.
Neurotoxicology, 2009 Jan , 30 (81-9).

115

Black JA et al. Sodium channel activity modulates multiple functions in microglia.
Glia, 2009 Aug 1 , 57 (1072-81).

116

Desaphy JF et al. Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine.
Pain, 2009 Apr , 142 (225-35).

117

Pinto FM et al. Molecular and functional characterization of voltage-gated sodium channels in human sperm.
Reprod. Biol. Endocrinol., 2009 , 7 (71).

118

McArdle EJ et al. Novel SCN1A frameshift mutation with absence of truncated Nav1.1 protein in severe myoclonic epilepsy of infancy.
Am. J. Med. Genet. A, 2008 Sep 15 , 146A (2421-3).

119

Fukuoka T et al. Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons.
J. Comp. Neurol., 2008 Sep 10 , 510 (188-206).

120

Duflocq A et al. Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments.
Mol. Cell. Neurosci., 2008 Oct , 39 (180-92).

121

Long YS et al. Identification of the promoter region and the 5'-untranslated exons of the human voltage-gated sodium channel Nav1.1 gene (SCN1A) and enhancement of gene expression by the 5'-untranslated exons.
J. Neurosci. Res., 2008 Nov 15 , 86 (3375-81).

122

Usuki S et al. Topology and patch-clamp analysis of the sodium channel in relationship to the anti-lipid a antibody in campylobacteriosis.
J. Neurosci. Res., 2008 Nov 15 , 86 (3359-74).

123

Blumenfeld H et al. Early treatment suppresses the development of spike-wave epilepsy in a rat model.
Epilepsia, 2008 Mar , 49 (400-9).

124

Zaharenko AJ et al. Revisiting cangitoxin, a sea anemone peptide: purification and characterization of cangitoxins II and III from the venom of Bunodosoma cangicum.
Toxicon, 2008 Jun 1 , 51 (1303-7).

125

Ragsdale DS How do mutant Nav1.1 sodium channels cause epilepsy?
, 2008 Jun , 58 (149-59).

126

Cestèle S et al. Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel.
J. Neurosci., 2008 Jul 16 , 28 (7273-83).

127

Guo F et al. Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat.
Brain Res. Bull., 2008 Jan 31 , 75 (179-87).

128

Lorincz A et al. Cell-type-dependent molecular composition of the axon initial segment.
J. Neurosci., 2008 Dec 31 , 28 (14329-40).

129

Black JA et al. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.
Ann. Neurol., 2008 Dec , 64 (644-53).

130

Kaneko Y et al. Expression of Nav1.1 in rat retinal AII amacrine cells.
Neurosci. Lett., 2007 Sep 7 , 424 (83-8).

131

Kalume F et al. Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.
J. Neurosci., 2007 Oct 10 , 27 (11065-74).

132

Rusconi R et al. Modulatory proteins can rescue a trafficking defective epileptogenic Nav1.1 Na+ channel mutant.
J. Neurosci., 2007 Oct 10 , 27 (11037-46).

133

Fry M et al. Differentiated pattern of sodium channel expression in dissociated Purkinje neurons maintained in long-term culture.
J. Neurochem., 2007 May , 101 (737-48).

134

Du Y et al. Downregulation of neuronal sodium channel subunits Nav1.1 and Nav1.6 in the sinoatrial node from volume-overloaded heart failure rat.
Pflugers Arch., 2007 Jun , 454 (451-9).

135

Huang X et al. [Expression and function of voltage-gated Na+ channel isoforms in rat sinoatrial node]
Nan Fang Yi Ke Da Xue Xue Bao, 2007 Jan , 27 (52-5).

136

Barela AJ et al. An epilepsy mutation in the sodium channel SCN1A that decreases channel excitability.
J. Neurosci., 2006 Mar 8 , 26 (2714-23).

137

de Ruiter MM et al. Voltage-gated sodium channels in cerebellar Purkinje cells of mormyrid fish.
J. Neurophysiol., 2006 Jul , 96 (378-90).

138

Vanoye CG et al. Single-channel properties of human NaV1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy.
J. Gen. Physiol., 2006 Jan , 127 (1-14).

139

Jarnot M et al. Immunolocalization of NaV1.2 channel subtypes in rat and cat brain and spinal cord with high affinity antibodies.
Brain Res., 2006 Aug 30 , 1107 (1-12).

140

Leão RN et al. Altered sodium currents in auditory neurons of congenitally deaf mice.
Eur. J. Neurosci., 2006 Aug , 24 (1137-46).

141

Depienne C et al. Parental mosaicism can cause recurrent transmission of SCN1A mutations associated with severe myoclonic epilepsy of infancy.
Hum. Mutat., 2006 Apr , 27 (389).

142

Zhao P et al. Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury.
, 2006 , 2 (27).

143

Ebensperger G et al. Fetal brain hypometabolism during prolonged hypoxaemia in the llama.
J. Physiol. (Lond.), 2005 Sep 15 , 567 (963-75).

144

Ptak K et al. Sodium currents in medullary neurons isolated from the pre-Bötzinger complex region.
J. Neurosci., 2005 May 25 , 25 (5159-70).

145

Valdivia CR et al. Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.
J. Mol. Cell. Cardiol., 2005 Mar , 38 (475-83).

146

Pineda RH et al. Developmental, molecular, and genetic dissection of INa in vivo in embryonic zebrafish sensory neurons.
J. Neurophysiol., 2005 Jun , 93 (3582-93).

147

Marionneau C et al. Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart.
J. Physiol. (Lond.), 2005 Jan 1 , 562 (223-34).

148

Mantegazza M et al. Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures.
Proc. Natl. Acad. Sci. U.S.A., 2005 Dec 13 , 102 (18177-82).

149

Lei M et al. Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking.
J. Physiol. (Lond.), 2004 Sep 15 , 559 (835-48).

150

Klein JP et al. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy.
Brain Res., 2004 Mar 12 , 1000 (102-9).

151

Leipold E et al. Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.
Mol. Pharmacol., 2004 Mar , 65 (685-91).

152

Grieco TM et al. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin.
J. Neurosci., 2004 Jan 7 , 24 (35-42).

153

Oliveira JS et al. Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.
J. Biol. Chem., 2004 Aug 6 , 279 (33323-35).

154

Clancy CE et al. Theoretical investigation of the neuronal Na+ channel SCN1A: abnormal gating and epilepsy.
Biophys. J., 2004 Apr , 86 (2606-14).

155

Herzog RI et al. Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.
J. Neurosci., 2003 Sep 10 , 23 (8261-70).

156

Sugawara T et al. Nav1.1 channels with mutations of severe myoclonic epilepsy in infancy display attenuated currents.
Epilepsy Res., 2003 May , 54 (201-7).

157

Gennaro E et al. Familial severe myoclonic epilepsy of infancy: truncation of Nav1.1 and genetic heterogeneity.
, 2003 Mar , 5 (21-5).

158

Craner MJ et al. Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination.
Brain, 2003 Jul , 126 (1552-61).

159

Lossin C et al. Epilepsy-associated dysfunction in the voltage-gated neuronal sodium channel SCN1A.
J. Neurosci., 2003 Dec 10 , 23 (11289-95).

160

Vega AV et al. L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.
Brain Res. Mol. Brain Res., 2003 Aug 19 , 116 (115-25).

161

Schaller KL et al. Expression and distribution of voltage-gated sodium channels in the cerebellum.
Cerebellum, 2003 , 2 (2-9).

162

Alessandri-Haber N et al. Molecular determinants of emerging excitability in rat embryonic motoneurons.
J. Physiol. (Lond.), 2002 May 15 , 541 (25-39).

163

Ito M et al. Autosomal dominant epilepsy with febrile seizures plus with missense mutations of the (Na+)-channel alpha 1 subunit gene, SCN1A.
Epilepsy Res., 2002 Jan , 48 (15-23).

164

Dhar Malhotra J et al. Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes.
Circulation, 2001 Mar 6 , 103 (1303-10).

165

Sugawara T et al. Nav1.1 mutations cause febrile seizures associated with afebrile partial seizures.
Neurology, 2001 Aug 28 , 57 (703-5).

166

Maurice N et al. D1/D5 dopamine receptor activation differentially modulates rapidly inactivating and persistent sodium currents in prefrontal cortex pyramidal neurons.
J. Neurosci., 2001 Apr 1 , 21 (2268-77).