Channelpedia

ClC6

Description: chloride channel 6
Gene: Clcn6
Alias: clc-6, clcn6

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	1185	1	36939
Mouse	26372	4	34554
Rat	295586	5	30875

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_001286.5	5589
Mouse	NM_011929.3	5198
Rat	NM_001106479.1	3305

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	P51797	869
Mouse	O35454	870
Rat	D4A3H5	853

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NR_046428.2

5573

transcript variant 3

NM_001286.5

5589

NP_001277.2

869

transcript variant 1

isoform 1

NM_001256959.2

5523

NP_001243888.2

847

transcript variant 2

isoform 2

Known

NM_001106479.1

3305

NP_001099949.1

870

Predicted

XR_592730.3

2511

transcript variant X2

XM_006239378.4

3111

XP_006239440.1

803

transcript variant X1

isoform X1

XM_039109377.1

1763

XP_038965305.1

477

transcript variant X4

isoform X3

XM_039109375.1

2265

XP_038965303.1

689

transcript variant X3

isoform X2

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Post-Translational Modifications

PTM

Position

Type

Modified residue

773

Phosphoserine

Glycosylation

410

N-linked (GlcNAc...) asparagine

Glycosylation

422

N-linked (GlcNAc...) asparagine

Glycosylation

432

N-linked (GlcNAc...) asparagine

Modified residue

774

Phosphoserine

Glycosylation

410

N-linked (GlcNAc...) asparagine

Glycosylation

423

N-linked (GlcNAc...) asparagine

Glycosylation

433

N-linked (GlcNAc...) asparagine

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Structure

ClC6 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	4941.76	source
Mouse	4329.15	source
Rat	5558.30	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/108/ , accessed on 2025 Nov 03

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