Cav1.2
724 literature references associated to Cav1.2
1
Morishima M
et al.
Atrial Fibrillation-Mediated Upregulation of miR-30d Regulates Myocardial Electrical Remodeling of the G-Protein-Gated K(+) Channel, IK.ACh.
Circ. J.,
2016
May
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2
Sutphin BS
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Molecular and Functional Characterization of Rare CACNA1C Variants in Sudden Unexplained Death in the Young.
Congenit Heart Dis,
2016
May
24
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3
Zeng H
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Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes.
J Pharmacol Toxicol Methods,
2016
May
21
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4
Yu L
et al.
Role of protein phosphatases in the run down of guinea pig cardiac Cav1.2 Ca2+ channels.
Am. J. Physiol., Cell Physiol.,
2016
May
15
, 310 (C773-9).
5
Jiang M
et al.
JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy.
Heart Rhythm,
2016
Mar
, 13 (743-752).
6
Santamaria-Herrera MA
et al.
MDIMP, a novel cardiac Ca(2+) channel blocker with atrial selectivity.
Eur. J. Pharmacol.,
2016
Jun
15
, 781 (218-28).
7
Savi M
et al.
Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart.
Am. J. Physiol. Heart Circ. Physiol.,
2016
Jun
1
, 310 (H1622-48).
8
Basheer WA
et al.
Connexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium.
Circ Arrhythm Electrophysiol,
2016
Jun
, 9 (e001357).
9
Tétreault MP
et al.
Identification of glycosylation sites essential for surface expression of the CaVα2δ 1 subunit and modulation of the cardiac CaV1.2 channel activity.
J. Biol. Chem.,
2016
Jan
7
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10
Yang W
et al.
Cannabinoid receptor agonists modulate calcium channels in rat retinal müller cells.
Neuroscience,
2016
Jan
28
, 313 (213-24).
11
Fu Y
et al.
Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads.
Circulation,
2016
Jan
26
, 133 (388-97).
12
Li B
et al.
Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression.
Science,
2016
Feb
19
, 351 (863-7).
13
Branch SY
et al.
Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease.
J. Neurosci.,
2016
Apr
6
, 36 (4026-37).
14
Crumb WJ
et al.
An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel.
J Pharmacol Toxicol Methods,
2016
Apr
6
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15
Dick IE
et al.
Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivation.
Nat Commun,
2016
, 7 (10370).
16
Nassal DM
et al.
Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role.
PLoS ONE,
2016
, 11 (e0146561).
17
Muralidharan P
et al.
Evidence for redox sensing by a human cardiac calcium channel.
Sci Rep,
2016
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18
Zhao Y
et al.
Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord,
2016
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19
Shemarova IV
et al.
[MECHANISMS OF THE EFFECT OF Li+ ON MYOCARDIUM OF VERTEBRATES].
Zh. Evol. Biokhim. Fiziol.,
2015 May-Jun
, 51 (181-6).
20
Corona-Rivera JR
et al.
Unusual retrospective prenatal findings in a male newborn with Timothy syndrome type 1.
Eur J Med Genet,
2015 Jun-Jul
, 58 (332-5).
21
Ebbers L
et al.
L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.
J. Biol. Chem.,
2015
Sep
25
, 290 (23692-710).
22
Kumar D
et al.
Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery.
Sleep,
2015
Sep
, 38 (1371-80).
23
Jiang H
et al.
Evaluating the association between CACNA1C rs1006737 and schizophrenia risk: A meta-analysis.
Asia Pac Psychiatry,
2015
Sep
, 7 (260-7).
24
Endo R
et al.
Carvedilol Suppresses Apoptosis and Ion Channel Remodelling of HL-1 Cardiac Myocytes Expressing E334K cMyBPC.
Drug Res (Stuttg),
2015
Oct
19
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25
Butler MG
et al.
Currently recognized genes for schizophrenia: High-resolution chromosome ideogram representation.
Am. J. Med. Genet. B Neuropsychiatr. Genet.,
2015
Oct
13
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26
Park SJ
et al.
Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.
Biochim. Biophys. Acta,
2015
Oct
, 1848 (2092-100).
27
Koczor CA
et al.
Methamphetamine and HIV-Tat alter murine cardiac DNA methylation and gene expression.
Toxicol. Appl. Pharmacol.,
2015
Nov
1
, 288 (409-19).
28
Liu SY
et al.
Nucleotides maintain the activity of Cav1.2 channels in guinea-pig ventricular myocytes.
Biochem. Biophys. Res. Commun.,
2015
May
8
, 460 (813-8).
29
Le Scouarnec S
et al.
Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome.
Hum. Mol. Genet.,
2015
May
15
, 24 (2757-63).
30
Kryshtal DO
et al.
Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2.
J. Mol. Cell. Cardiol.,
2015
May
, 82 (75-83).
31
N'Gouemo P
et al.
Alcohol Withdrawal-Induced Seizure Susceptibility is Associated with an Upregulation of CaV1.3 Channels in the Rat Inferior Colliculus.
Int. J. Neuropsychopharmacol.,
2015
May
, 18 (pyu123).
32
Matus M
et al.
Upregulation of SERCA2a following short-term ACE inhibition (by enalaprilat) alters contractile performance and arrhythmogenicity of healthy myocardium in rat.
Mol. Cell. Biochem.,
2015
May
, 403 (199-208).
33
Zhang Q
et al.
Effect of sulfur dioxide inhalation on the expression of KATP and L-Ca(2+) channels in rat hearts.
Environ. Toxicol. Pharmacol.,
2015
May
, 39 (1132-8).
34
Harraz OF
et al.
CaV1.2/CaV3.x channels mediate divergent vasomotor responses in human cerebral arteries.
J. Gen. Physiol.,
2015
May
, 145 (405-18).
35
Li R
et al.
Hypoxia-inducible factor-1α regulates the expression of L-type voltage-dependent Ca(2+) channels in PC12 cells under hypoxia.
Cell Stress Chaperones,
2015
May
, 20 (507-16).
36
Dionisio N
et al.
Homer proteins mediate the interaction between STIM1 and Cav1.2 channels.
Biochim. Biophys. Acta,
2015
May
, 1853 (1145-53).
37
Andres MA
et al.
Methamphetamine acutely inhibits voltage-gated calcium channels but chronically upregulates L-type channels.
J. Neurochem.,
2015
Mar
25
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38
Zhang Q
et al.
Effects of sodium metabisulfite on the expression of BK(Ca), K(ATP), and L-Ca(2+) channels in rat aortas in vivo and in vitro.
J. Hazard. Mater.,
2015
Mar
2
, 284 (151-62).
39
Ament SA
et al.
Rare variants in neuronal excitability genes influence risk for bipolar disorder.
Proc. Natl. Acad. Sci. U.S.A.,
2015
Mar
17
, 112 (3576-81).
40
Kim SY
et al.
DUSP4 regulates neuronal differentiation and calcium homeostasis by modulating ERK1/2 phosphorylation.
Stem Cells Dev.,
2015
Mar
15
, 24 (686-700).
41
Wemhöner K
et al.
Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.
J. Mol. Cell. Cardiol.,
2015
Mar
, 80 (186-95).
42
Daschil N
et al.
L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model.
Neurobiol. Aging,
2015
Mar
, 36 (1333-41).
43
Hurley MJ
et al.
Calcium CaV1 channel subtype mRNA expression in Parkinson's disease examined by in situ hybridization.
J. Mol. Neurosci.,
2015
Mar
, 55 (715-24).
44
Yang G
et al.
CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.
Cell. Mol. Life Sci.,
2015
Mar
, 72 (1197-207).
45
Hiippala A
et al.
Expanding the phenotype of Timothy syndrome type 2: an adolescent with ventricular fibrillation but normal development.
Am. J. Med. Genet. A,
2015
Mar
, 167A (629-34).
46
Cheli VT
et al.
Voltage-gated Ca2+ entry promotes oligodendrocyte progenitor cell maturation and myelination in vitro.
Exp. Neurol.,
2015
Mar
, 265 (69-83).
47
Zhang Q
et al.
The molecular mechanism of the effect of sulfur dioxide inhalation on the potassium and calcium ion channels in rat aortas.
Hum Exp Toxicol,
2015
Jun
24
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48
Zhou FJ
et al.
Two New Classes of T-Type Calcium Channel Inhibitors with New Chemical Scaffolds from Ganoderma cochlear.
Org. Lett.,
2015
Jun
19
, 17 (3082-5).
49
Bladen C
et al.
1,4-Dihydropyridine derivatives with T-type calcium channel blocking activity attenuate inflammatory and neuropathic pain.
Pflugers Arch.,
2015
Jun
, 467 (1237-47).
50
Wang F
et al.
Ammonium increases Ca(2+) signalling and upregulates expression of Cav1.2 gene in astrocytes in primary cultures and in the in vivo brain.
Acta Physiol (Oxf),
2015
Jun
, 214 (261-74).
51
Pasparakis E
et al.
The effects of the CACNA1C rs1006737 A/G on affective startle modulation in healthy males.
Eur. Psychiatry,
2015
Jun
, 30 (492-8).
52
Grajales L
et al.
Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.
Stem Cell Rev,
2015
Jun
, 11 (408-22).
53
Sun Z
et al.
MiR-103 inhibits osteoblast proliferation mainly through suppressing Cav1.2 expression in simulated microgravity.
Bone,
2015
Jul
, 76 (121-8).
54
Liu T
et al.
Effects of Dantrolene Treatment on Ventricular Electrophysiology and Arrhythmogenesis in Rats With Chronic β-Adrenergic Receptor Activation.
J. Cardiovasc. Pharmacol. Ther.,
2015
Jul
, 20 (414-27).
55
Wu ZJ
et al.
Characterization of a Chinese KCNQ1 mutation (R259H) that shortens repolarization and causes short QT syndrome 2.
J Geriatr Cardiol,
2015
Jul
, 12 (394-401).
56
Sun Y
et al.
Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel.
J. Pharmacol. Sci.,
2015
Jul
, 128 (137-43).
57
Chong E
et al.
Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Heart Rhythm,
2015
Jan
30
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58
Bourdin B
et al.
Functional characterization of CaVα2δ mutations associated with sudden cardiac death.
J. Biol. Chem.,
2015
Jan
30
, 290 (2854-69).
59
Yang L
et al.
The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.
J. Biol. Chem.,
2015
Jan
23
, 290 (2166-74).
60
Lee A
et al.
Characterization of Cav1.4 complexes (α11.4, β2, and α2δ4) in HEK293T cells and in the retina.
J. Biol. Chem.,
2015
Jan
16
, 290 (1505-21).
61
Polster A
et al.
Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2+ channels.
Proc. Natl. Acad. Sci. U.S.A.,
2015
Jan
13
, 112 (602-6).
62
Boczek NJ
et al.
Novel Timothy syndrome mutation leading to increase in CACNA1C window current.
Heart Rhythm,
2015
Jan
, 12 (211-9).
63
Espinosa-Parrilla JF
et al.
The L-type voltage-gated calcium channel modulates microglial pro-inflammatory activity.
Mol. Cell. Neurosci.,
2015
Jan
, 64 (104-15).
64
Liao P
et al.
Alternative splicing generates a novel truncated Cav1.2 channel in neonatal rat heart.
J. Biol. Chem.,
2015
Feb
18
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65
Männikkö R
et al.
Pharmacological and electrophysiological characterisation of hERG activator AZSMO-23.
Br. J. Pharmacol.,
2015
Feb
12
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66
Yoshimizu T
et al.
Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons.
Mol. Psychiatry,
2015
Feb
, 20 (162-9).
67
Tikhonov DB
et al.
State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels.
Pflugers Arch.,
2015
Feb
, 467 (253-66).
68
Singhal K
et al.
L-type calcium channel blocker ameliorates diabetic encephalopathy by modulating dysregulated calcium homeostasis.
J. Neurosci. Res.,
2015
Feb
, 93 (296-308).
69
Zhu W
et al.
Molecular motions that shape the cardiac action potential: Insights from voltage clamp fluorometry.
Prog. Biophys. Mol. Biol.,
2015
Dec
25
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70
Zhou MH
et al.
Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.
J. Biol. Chem.,
2015
Dec
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71
Rougier JS
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Cardiac voltage-gated calcium channel macromolecular complexes.
Biochim. Biophys. Acta,
2015
Dec
18
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72
Garau G
et al.
Heparin/heparan sulfates bind to and modulate neuronal L-type (Cav1.2) voltage-dependent Ca(2+) channels.
Exp. Neurol.,
2015
Dec
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73
Ji L
et al.
Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7.
J. Hypertens.,
2015
Dec
, 33 (2431-42).
74
Kaur G
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A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.
J. Biol. Chem.,
2015
Aug
21
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75
Duan XQ
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Mechanisms of Intracellular Calcium Homeostasis in MC3T3-E1 Cells and Bone Tissues of Sprague-Dawley Rats Exposed to Fluoride.
Biol Trace Elem Res,
2015
Aug
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76
Grubb S
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Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2.
Am. J. Physiol. Heart Circ. Physiol.,
2015
Aug
1
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77
Lv N
et al.
Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.
Seizure,
2015
Aug
, 30 (64-9).
78
Porcelli S
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CACNA1C gene and schizophrenia: a case-control and pharmacogenetic study.
Psychiatr. Genet.,
2015
Aug
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79
Zhang Q
et al.
The molecular mechanisms of sodium metabisulfite on the expression of K ATP and L-Ca2+ channels in rat hearts.
Regul. Toxicol. Pharmacol.,
2015
Aug
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80
Ou X
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CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity.
Neurosci Biobehav Rev,
2015
Aug
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81
Park HJ
et al.
Asn-Linked Glycosylation Contributes to Surface Expression and Voltage-Dependent Gating of Cav1.2 Ca²⁺ Channel.
J. Microbiol. Biotechnol.,
2015
Aug
, 25 (1371-9).
82
Lavorato M
et al.
Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2.
J. Muscle Res. Cell. Motil.,
2015
Apr
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83
Simms BA
et al.
The Cav1.2 N terminus contains a CaM kinase site that modulates channel trafficking and function.
Pflugers Arch.,
2015
Apr
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84
Staehlke S
et al.
Intracellular calcium dynamics dependent on defined microtopographical features of titanium.
Biomaterials,
2015
Apr
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85
Lichvárová L
et al.
Ca(V)1.2 and Ca(V)1.3 L-type calcium channels regulate the resting membrane potential but not the expression of calcium transporters in differentiated PC12 cells.
Gen. Physiol. Biophys.,
2015
Apr
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86
Catterall WA
Regulation of Cardiac Calcium Channels in the Fight-or-Flight Response.
Curr Mol Pharmacol,
2015
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87
Stanislav B
et al.
Direct Estimation of CaV1.2 Gating Parameters: Quantification of Voltage Sensor - Pore Transductions and their Modulation by FLP 64176.
Curr Mol Pharmacol,
2015
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88
Tang J
et al.
Chronic hypoxia in pregnancy affected vascular tone of renal interlobar arteries in the offspring.
Sci Rep,
2015
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89
Yamanushi TT
et al.
Comparison of formaldehyde and methanol fixatives used in the detection of ion channel proteins in isolated rat ventricular myocytes by immunofluorescence labelling and confocal microscopy.
Folia Morphol. (Warsz),
2015
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90
Wang J
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MicroRNA profiling in the left atrium in patients with non-valvular paroxysmal atrial fibrillation.
BMC Cardiovasc Disord,
2015
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91
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Arrhythmogenic effects of mutated L-type Ca(2+)-channels on an optogenetically paced muscular pump in Caenorhabditis elegans.
Sci Rep,
2015
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92
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Simulated microgravity inhibits L-type calcium channel currents partially by the up-regulation of miR-103 in MC3T3-E1 osteoblasts.
Sci Rep,
2015
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93
Tan WL
et al.
HOTAIR inhibited intracellular Ca2+ via regulation of Cav1.2 channel in human cardiomyocytes.
Cell. Mol. Biol. (Noisy-le-grand),
2015
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94
Allegue C
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Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.
PLoS ONE,
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95
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Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins.
Transl Psychiatry,
2015
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96
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Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism.
PLoS ONE,
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97
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Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles.
Neuropsychobiology,
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98
Wang CY
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Meta-Analysis of Public Microarray Datasets Reveals Voltage-Gated Calcium Gene Signatures in Clinical Cancer Patients.
PLoS ONE,
2015
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99
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Quantitative Profiling of the Effects of Vanoxerine on Human Cardiac Ion Channels and its Application to Cardiac Risk.
Sci Rep,
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100
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Graded Ca²⁺/calmodulin-dependent coupling of voltage-gated CaV1.2 channels.
Elife,
2015
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101
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Single channel measurements demonstrate the voltage dependence of permeation through N-type and L-type CaV channels.
Channels (Austin),
2015
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102
Brun J
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Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells.
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103
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What is the impact of genome-wide supported risk variants for schizophrenia and bipolar disorder on brain structure and function? A systematic review.
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104
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Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
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105
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Dentition abnormalities in a Timothy syndrome patient with a novel genetic mutation: a case report.
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Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C.
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Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.
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108
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Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.
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High-sucrose diets in pregnancy alter angiotensin II-mediated pressor response and microvessel tone via the PKC/Cav1.2 pathway in rat offspring.
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Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
Mol. Psychiatry,
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111
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A novel calmodulin site in the Cav1.2 N-terminus regulates calcium-dependent inactivation.
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112
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Fetal programming by high-sucrose diet during pregnancy affects the vascular angiotensin II receptor-PKC-L-type Ca(2+) channels (Cav1.2) axis to enhance pressor responses.
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113
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Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data.
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114
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L-type calcium channel modulates cystic kidney phenotype.
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115
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The effect of omega-3 on cognition in hypothyroid adult male rats.
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Colchicine suppresses atrial fibrillation in failing heart.
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117
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Neuroprotective effect of weak static magnetic fields in primary neuronal cultures.
Neuroscience,
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118
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Voltage-gated calcium channels in the human adrenal and primary aldosteronism.
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119
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Chronic atrial fibrillation increases microRNA-21 in human atrial myocytes decreasing L-type calcium current.
Circ Arrhythm Electrophysiol,
2014
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120
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Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Ca v1.2 channels.
Pflugers Arch.,
2014
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121
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Effects of gaseous sulfur dioxide and its derivatives on the expression of KATP, BKCa and L-Ca(2+) channels in rat aortas in vitro.
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122
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The individual N- and C-lobes of calmodulin tether to the Cav1.2 channel and rescue the channel activity from run-down in ventricular myocytes of guinea-pig heart.
FEBS Lett.,
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A role for noncoding variation in schizophrenia.
Cell Rep,
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Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.
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Cilostazol ameliorates atrial ionic remodeling in long-term rapid atrial pacing dogs.
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126
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Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine.
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CACNA1C genomewide supported psychosis genetic variation affects cortical brain white matter integrity in Chinese patients with schizophrenia.
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128
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