TRPV6

1

Wongdee K et al. Intestinal mucosal changes and upregulated calcium transporter and FGF-23 expression during lactation: Contribution of lactogenic hormone prolactin.
Arch. Biochem. Biophys., 2016 Jan 15 , 590 (109-17).

2

Lee CT et al. The role of calbindin-D28k on renal calcium and magnesium handling during treatment with loop and thiazide diuretics.
Am. J. Physiol. Renal Physiol., 2016 Feb 1 , 310 (F230-6).

3

Velisetty P et al. A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.
Sci Rep, 2016 , 6 (27652).

4

Kuwabara A et al. [The role of gastro-intestinal tract in the calcium absorption].
Clin Calcium, 2015 Nov , 25 (1607-12).

5

Huber K et al. Modulation of small intestinal phosphate transporter by dietary supplements of mineral phosphorus and phytase in broilers.
Poult. Sci., 2015 May , 94 (1009-17).

6

Wu P et al. Advanced oxidation protein products decrease the expression of calcium transport channels in small intestinal epithelium via the p44/42 MAPK signaling pathway.
Eur. J. Cell Biol., 2015 Mar 6 , ().

7

De Clercq K et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle.
Hum. Reprod., 2015 Mar 27 , ().

8

Diaz de Barboza G et al. Molecular aspects of intestinal calcium absorption.
World J. Gastroenterol., 2015 Jun 21 , 21 (7142-54).

9

Vachel L et al. The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity.
Cell Calcium, 2015 Jan , 57 (38-48).

10

Yang H et al. Differential expression of calcium transport genes caused by COMT inhibition in the duodenum, kidney and placenta of pregnant mice.
Mol. Cell. Endocrinol., 2015 Feb 5 , 401 (45-55).

11

Lameris AL et al. Segmental transport of Ca²⁺ and Mg²⁺ along the gastrointestinal tract.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Feb 1 , 308 (G206-16).

12

Skrzypski M et al. TRPV6 channel modulates proliferation of insulin secreting INS-1E beta cell line.
Biochim. Biophys. Acta, 2015 Dec , 1853 (3202-10).

13

Tabur S et al. Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.
Eur Rev Med Pharmacol Sci, 2015 Apr , 19 (1388-97).

14

Somogyi CS et al. Polymodal Transient Receptor Potential Vanilloid (TRPV) Ion Channels in Chondrogenic Cells.
Int J Mol Sci, 2015 , 16 (18412-38).

15

Miura S et al. Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6.
Nat Commun, 2015 , 6 (8871).

16

Procino G et al. Rosiglitazone promotes AQP2 plasma membrane expression in renal cells via a Ca-dependent/cAMP-independent mechanism.
Cell. Physiol. Biochem., 2015 , 35 (1070-85).

17

Raphaël M et al. TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival.
Proc. Natl. Acad. Sci. U.S.A., 2014 Sep 16 , 111 (E3870-9).

18

Vigors S et al. Improvements in growth performance, bone mineral status and nutrient digestibility in pigs following the dietary inclusion of phytase are accompanied by modifications in intestinal nutrient transporter gene expression.
Br. J. Nutr., 2014 Sep 14 , 112 (688-97).

19

Giusti L et al. First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.
J. Cell. Mol. Med., 2014 Oct , 18 (1944-52).

20

Elias E et al. Bone mineral density and expression of vitamin D receptor-dependent calcium uptake mechanisms in the proximal small intestine after bariatric surgery.
Br J Surg, 2014 Nov , 101 (1566-75).

21

Dong XL et al. Estrogen deficiency-induced Ca balance impairment is associated with decrease in expression of epithelial Ca transport proteins in aged female rats.
Life Sci., 2014 Feb 6 , 96 (26-32).

22

Huynh KW et al. Structural insight into the assembly of TRPV channels.
Structure, 2014 Feb 4 , 22 (260-8).

23

Stoerger C et al. The transient receptor potential cation channel subfamily V member 6 (TRPV6): genetics, biochemical properties, and functions of exceptional calcium channel proteins.
Biochem. Cell Biol., 2014 Dec , 92 (441-8).

24

Lau JK et al. Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway.
Apoptosis, 2014 Aug , 19 (1190-201).

25

Kim SY et al. Reciprocal positive regulation between TRPV6 and NUMB in PTEN-deficient prostate cancer cells.
Biochem. Biophys. Res. Commun., 2014 Apr 25 , 447 (192-6).

26

Dai W et al. Calcium deficiency-induced and TRP channel-regulated IGF1R-PI3K-Akt signaling regulates abnormal epithelial cell proliferation.
Cell Death Differ., 2014 Apr , 21 (568-81).

27

Fan H et al. Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.
Asian Pac. J. Cancer Prev., 2014 , 15 (2559-63).

28

Fecher-Trost C et al. TRPV6 channels.
Handb Exp Pharmacol, 2014 , 222 (359-84).

29

Hummel DM et al. Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells.
J. Steroid Biochem. Mol. Biol., 2013 Oct 9 , ().

30

Kovacs G et al. Human TRPV5 and TRPV6: Key players in cadmium and zinc toxicity.
Cell Calcium, 2013 Oct , 54 (276-86).

31

Saul S et al. How ORAI and TRP channels interfere with each other: Interaction models and examples from the immune system and the skin.
Eur. J. Pharmacol., 2013 Nov 28 , ().

32

Chow EC et al. Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.
Am. J. Physiol. Endocrinol. Metab., 2013 May 1 , 304 (E977-89).

33

Yang H et al. Differential expression of calcium transport channels in placenta primary cells and tissues derived from preeclamptic placenta.
Mol. Cell. Endocrinol., 2013 Mar 10 , 367 (21-30).

34

Fecher-Trost C et al. The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG.
J. Biol. Chem., 2013 Jun 7 , 288 (16629-44).

35

Hofer A et al. Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport.
Bioorg. Med. Chem., 2013 Jun 1 , 21 (3202-13).

36

Yang JH et al. Expression of TRPV6 and CaBP-D28k in the egg shell gland (uterus) during the oviposition cycle of the laying hen.
Br. Poult. Sci., 2013 Jun , 54 (398-406).

37

Morelli MB et al. Expression and Function of the Transient Receptor Potential Ion Channel Family in the Hematologic Malignancies.
Curr Mol Pharmacol, 2013 Jul 8 , ().

38

Wolf MT et al. Uromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis.
Kidney Int., 2013 Jul , 84 (130-7).

39

Kim S et al. Effects of octylphenol and bisphenol A on the expression of calcium transport genes in the mouse duodenum and kidney during pregnancy.
Toxicology, 2013 Jan 7 , 303 (99-106).

40

Cao C et al. Interplay between calmodulin and phosphatidylinositol 4,5-bisphosphate in Ca2+-induced inactivation of transient receptor potential vanilloid 6 channels.
J. Biol. Chem., 2013 Feb 22 , 288 (5278-90).

41

Yang H et al. Change of genes in calcium transport channels caused by hypoxic stress in the placenta, duodenum, and kidney of pregnant rats.
Biol. Reprod., 2013 Feb , 88 (30).

42

Kim SY et al. Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.
Cell Calcium, 2013 Feb , 53 (102-11).

43

Vassilieva IO et al. Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in human blood lymphocytes and Jurkat leukemia T cells.
J. Membr. Biol., 2013 Feb , 246 (131-40).

44

Cha SK et al. Flow-induced activation of TRPV5 and TRPV6 channels stimulates Ca(2+)-activated K(+) channel causing membrane hyperpolarization.
Biochim. Biophys. Acta, 2013 Dec , 1833 (3046-53).

45

Courjaret R et al. The Xenopus TRPV6 homolog encodes a Mg(2+) -permeant channel that is inhibited by interaction with TRPC1.
J. Cell. Physiol., 2013 Dec , 228 (2386-98).

46

Rievaj J et al. The Na⁺/H⁺ exchanger isoform 3 is required for active paracellular and transcellular Ca²⁺ transport across murine cecum.
Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Aug 15 , 305 (G303-13).

47

Shabir S et al. Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium.
Am. J. Physiol. Renal Physiol., 2013 Aug 1 , 305 (F396-406).

48

Colombini A et al. Evaluation of a possible direct effect by casein phosphopeptides on paracellular and vitamin D controlled transcellular calcium transport mechanisms in intestinal human HT-29 and Caco2 cell lines.
Food Funct, 2013 Aug , 4 (1195-203).

49

Breves JP et al. Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill.
Mol. Cell. Endocrinol., 2013 Apr 30 , 369 (98-106).

50

Guo Z et al. A novel ion channel formed by interaction of TRPML3 with TRPV5.
PLoS ONE, 2013 , 8 (e58174).

51

Loh NY et al. Autosomal dominant hypercalciuria in a mouse model due to a mutation of the epithelial calcium channel, TRPV5.
PLoS ONE, 2013 , 8 (e55412).

52

Bowen CV et al. In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin.
PLoS ONE, 2013 , 8 (e58866).

53

Bishnoi M et al. Expression of multiple Transient Receptor Potential channel genes in murine 3T3-L1 cell lines and adipose tissue.
Pharmacol Rep, 2013 , 65 (751-5).

54

Tomilin VN et al. [The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].
Tsitologiia, 2013 , 55 (300-6).

55

Noguchi TA et al. Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos.
Gene Expr. Patterns, 2012 Mar-Apr , 12 (154-63).

56

Jonchere VV et al. Identification of uterine ion transporters for mineralisation precursors of the avian eggshell.
BMC Physiol., 2012 Sep 4 , 12 (10).

57

Jiang Y et al. Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells.
Mol. Cell. Endocrinol., 2012 Sep 25 , 361 (31-9).

58

Schindl R et al. Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.
J. Biol. Chem., 2012 Oct 12 , 287 (35612-20).

59

Woudenberg-Vrenken TE et al. Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption.
Am. J. Physiol. Gastrointest. Liver Physiol., 2012 Oct , 303 (G879-85).

60

Cui M et al. Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice.
J. Bone Miner. Res., 2012 Oct , 27 (2097-107).

61

Jang Y et al. Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res., 2012 Oct , 35 (1823-30).

62

Peters AA et al. Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor-negative breast cancer.
Mol. Cancer Ther., 2012 Oct , 11 (2158-68).

63

Charoenphandhu N et al. Duodenal calcium transporter mRNA expression in stressed male rats treated with diazepam, fluoxetine, reboxetine, or venlafaxine.
Mol. Cell. Biochem., 2012 Oct , 369 (87-94).

64

Weng ZP et al. [Effects of transient receptor potential V6 silence on proliferation and apoptosis of trophoblasts].
Zhonghua Fu Chan Ke Za Zhi, 2012 Oct , 47 (777-80).

65

Woudenberg-Vrenken TE et al. Characterization of vitamin D-deficient klotho(-/-) mice: do increased levels of serum 1,25(OH)2D3 cause disturbed calcium and phosphate homeostasis in klotho(-/-) mice?
Nephrol. Dial. Transplant., 2012 Nov , 27 (4061-8).

66

Weissgerber P et al. Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.
J. Biol. Chem., 2012 May 25 , 287 (17930-41).

67

Ouadid-Ahidouch H et al. TRP calcium channel and breast cancer: expression, role and correlation with clinical parameters.
, 2012 May 24 , ().

68

Nandhikonda P et al. Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators.
J. Med. Chem., 2012 May 24 , 55 (4640-51).

69

An J et al. The toxic effects of Aroclor 1254 exposure on the osteoblastic cell line MC3T3-E1 and its molecular mechanism.
Toxicology, 2012 May 16 , 295 (8-14).

70

van der Eerden BC et al. The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.
J. Cell. Physiol., 2012 May , 227 (1951-9).

71

Wu G et al. Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease.
Am. J. Physiol., Cell Physiol., 2012 May , 302 (C1479-91).

72

Koo TH et al. Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).
Mol. Reprod. Dev., 2012 May , 79 (346-55).

73

Lehen'kyi V et al. The role of the TRPV6 channel in cancer.
J. Physiol. (Lond.), 2012 Mar 15 , 590 (1369-76).

74

Brittain JM et al. Regulation of CREB signaling through L-Type Ca ( 2+) channels by Nipsnap-2.
, 2012 Mar 1 , 6 ().

75

Oliveira AG et al. Involvement of the transepithelial calcium transport disruption and the formation of epididymal stones in roosters.
Reproduction, 2012 Jun , 143 (835-44).

76

Kovalevskaya NV et al. The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.
J. Struct. Funct. Genomics, 2012 Jun , 13 (91-100).

77

Cehak A et al. In vitro studies on intestinal calcium and phosphate transport in horses.
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol., 2012 Feb , 161 (259-64).

78

Kovacs G et al. Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB).
Cell Calcium, 2012 Dec , 52 (468-80).

79

Muscher AS et al. Ex vivo intestinal studies on calcium and phosphate transport in growing goats fed a reduced nitrogen diet.
Br. J. Nutr., 2012 Aug , 108 (628-37).

80

Khuituan P et al. Fibroblast growth factor-23 abolishes 1,25-dihydroxyvitamin D₃-enhanced duodenal calcium transport in male mice.
Am. J. Physiol. Endocrinol. Metab., 2012 Apr , 302 (E903-13).

81

Hdud IM et al. Expression of Transient Receptor Potential Vanilloid (TRPV) Channels in Different Passages of Articular Chondrocytes.
Int J Mol Sci, 2012 , 13 (4433-45).

82

Lee CT et al. Renal adaptation to gentamicin-induced mineral loss.
Am. J. Nephrol., 2012 , 35 (279-86).

83

Lieben L et al. The Involvement of TRP Channels in Bone Homeostasis.
Front Endocrinol (Lausanne), 2012 , 3 (99).

84

Sprekeler N et al. TRPV6 and Calbindin-D9k-expression and localization in the bovine uterus and placenta during pregnancy.
Reprod. Biol. Endocrinol., 2012 , 10 (66).

85

Lee CT et al. Variations of dietary salt and fluid modulate calcium and magnesium transport in the renal distal tubule.
Nephron Physiol, 2012 , 122 (19-27).

86

Kim JA et al. Expression patterns and potential action of the calcium transport genes Trpv5, Trpv6, Ncx1 and Pmca1b in the canine duodenum, kidney and uterus.
In Vivo, 2011 Sep-Oct , 25 (773-80).

87

Gkika D et al. TRP channels in prostate cancer: the good, the bad and the ugly?
Asian J. Androl., 2011 Sep , 13 (673-6).

88

Zakharian E et al. Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5) P₂.
FASEB J., 2011 Nov , 25 (3915-28).

89

Brown AJ et al. The vitamin D analog 1α,25-Dihydroxy-2β-(3-Hydroxypropyloxy) vitamin D(3) (Eldecalcitol) is a potent regulator of calcium and phosphate metabolism.
Calcif. Tissue Int., 2011 Nov , 89 (372-8).

90

Hwang I et al. Tissue-specific expression of the calcium transporter genes TRPV5, TRPV6, NCX1, and PMCA1b in the duodenum, kidney and heart of Equus caballus.
J. Vet. Med. Sci., 2011 Nov , 73 (1437-44).

91

Holzer P Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
, 2011 Mar 17 , ().

92

Haché S et al. Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.
J. Cell. Mol. Med., 2011 Mar , 15 (654-67).

93

Kovalevskaya NV et al. Expression and purification of the C-terminal fragments of TRPV5/6 channels.
, 2011 Jun 2 , ().

94

Vanoevelen J et al. Trpv5/6 is vital for epithelial calcium uptake and bone formation.
, 2011 Jun 13 , ().

95

Jung EM et al. Duodenal and renal transient receptor potential vanilloid 6 is regulated by sex steroid hormones, estrogen and progesterone, in immature rats.
J. Vet. Med. Sci., 2011 Jun , 73 (711-6).

96

Kellett GL Alternative perspective on intestinal calcium absorption: proposed complementary actions of Ca(v)1.3 and TRPV6.
Nutr. Rev., 2011 Jul , 69 (347-70).

97

Holzer P TRP channels in the digestive system.
Curr Pharm Biotechnol, 2011 Jan 1 , 12 (24-34).

98

Kim YK et al. 191 TRANSIENT RECEPTOR POTENTIAL SUPERFAMILY OF ION CHANNELS, TRPV6, IS CONSTITUTIVELY EXPRESSED AND REGULATED BY ESTROGEN IN THE HUMAN UTERUS DURING THE MENSTRUAL CYCLE.
, 2011 Jan , 23 (196).

99

Kovacs G et al. Heavy metal cations permeate the TRPV6 epithelial cation channel.
Cell Calcium, 2011 Jan , 49 (43-55).

100

Lehen'kyi V et al. Acceleration of keratinocyte differentiation by transient receptor potential vanilloid (TRPV6) channel activation.
J Eur Acad Dermatol Venereol, 2011 Feb , 25 Suppl 1 (12-8).

101

Zebger-Gong H et al. 1,25-Dihydroxyvitamin D3-induced aortic calcifications in experimental uremia: up-regulation of osteoblast markers, calcium-transporting proteins and osterix.
J. Hypertens., 2011 Feb , 29 (339-48).

102

Holakovska B et al. Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.
Amino Acids, 2011 Feb , 40 (741-8).

103

Landowski CP et al. Chemical inhibitors of the calcium entry channel TRPV6.
Pharm. Res., 2011 Feb , 28 (322-30).

104

Wu Y et al. Decreased expression of the epithelial Ca2+ channel TRPV5 and TRPV6 in human renal cell carcinoma associated with vitamin D receptor.
J. Urol., 2011 Dec , 186 (2419-25).

105

Yang JH et al. Localisation and expression of TRPV6 in all intestinal segments and kidney of laying hens.
Br. Poult. Sci., 2011 Aug , 52 (507-16).

106

Spehr J et al. G protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation.
J. Biol. Chem., 2011 Apr 15 , 286 (13184-92).

107

Xi Q et al. Adenovirus-delivered microRNA targeting the vitamin D receptor reduces intracellular Ca²⁺ concentrations by regulating the expression of Ca²⁺-transport proteins in renal epithelial cells.
BJU Int., 2011 Apr , 107 (1314-9).

108

Yang H et al. Coexpression and estrogen-mediated regulation of TRPV6 and PMCA1 in the human endometrium during the menstrual cycle.
Mol. Reprod. Dev., 2011 Apr , 78 (274-82).

109

Weissgerber P et al. Male Fertility Depends on Ca2+ Absorption by TRPV6 in Epididymal Epithelia.
Sci Signal, 2011 , 4 (ra27).

110

Peng JB TRPV5 and TRPV6 in transcellular Ca(2+) transport: regulation, gene duplication, and polymorphisms in African populations.
Adv. Exp. Med. Biol., 2011 , 704 (239-75).

111

Little R et al. The Transient Receptor Potential Ion Channel TRPV6 Is Expressed at Low Levels in Osteoblasts and Has Little Role in Osteoblast Calcium Uptake.
PLoS ONE, 2011 , 6 (e28166).

112

Sprekeler N et al. Expression patterns of intestinal calcium transport factors and ex-vivo absorption of calcium in horses.
BMC Vet. Res., 2011 , 7 (65).

113

Lehen'kyi V et al. TRPV6 determines the effect of vitamin D3 on prostate cancer cell growth.
PLoS ONE, 2011 , 6 (e16856).

114

Dhennin-Duthille I et al. High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters.
Cell. Physiol. Biochem., 2011 , 28 (813-22).

115

Zhang W et al. Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2.
J. Biol. Chem., 2010 Nov 19 , 285 (36586-96).

116

Yang SS et al. Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome.
Hum. Mutat., 2010 Dec , 31 (1304-15).

117

Inoue J et al. Quercetin enhances VDR activity, leading to stimulation of its target gene expression in Caco-2 cells.
J. Nutr. Sci. Vitaminol., 2010 , 56 (326-30).

118

Sudo Y et al. Derived (mutated)-types of TRPV6 channels elicit greater Ca²+ influx into the cells than ancestral-types of TRPV6: evidence from Xenopus oocytes and mammalian cell expression system.
J. Pharmacol. Sci., 2010 , 114 (281-91).