TRPM2

1

Kahya MC et al. Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca(2+) Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of Diabetic Rats by Melatonin and Selenium.
Mol. Neurobiol., 2016 Mar 9 , ().

2

Ugan Y et al. Anti-tumor Necrosis Factor Alpha (Infliximab) Attenuates Apoptosis, Oxidative Stress, and Calcium Ion Entry Through Modulation of Cation Channels in Neutrophils of Patients with Ankylosing Spondylitis.
J. Membr. Biol., 2016 Mar 8 , ().

3

Demirdas A et al. Short-Term Ketamine Treatment Decreases Oxidative Stress Without Influencing TRPM2 and TRPV1 Channel Gating in the Hippocampus and Dorsal Root Ganglion of Rats.
Cell. Mol. Neurobiol., 2016 Mar 2 , ().

4

Shimizu K et al. Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels.
Exp. Neurol., 2016 Jan , 275 Pt 1 (78-83).

5

Bal R et al. Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat.
Arch Med Sci, 2016 Feb 1 , 12 (208-15).

6

Wu X et al. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 , 11 (e0155577).

7

Koh DW et al. Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel.
Oncol. Rep., 2015 Sep , 34 (1589-98).

8

Ostapchenko VG et al. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.
J. Neurosci., 2015 Nov 11 , 35 (15157-69).

9

Hopkins MM et al. Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells.
Int. J. Oncol., 2015 May , 46 (2267-76).

10

Tóth B et al. Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.
J. Gen. Physiol., 2015 May , 145 (419-30).

11

Kashio M et al. Redox signal-mediated enhancement of the temperature sensitivity of Transient Receptor Potential Melastatin 2 (TRPM2) elevated glucose-induced insulin secretion from pancreatic islets.
J. Biol. Chem., 2015 Mar 27 , ().

12

Li C et al. Non-NMDAR neuronal Ca(2+)-permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage.
Expert Opin. Ther. Targets, 2015 Mar 2 , (1-14).

13

Manna PT et al. TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death.
Biochem. J., 2015 Mar 15 , 466 (537-46).

14

Hoffman NE et al. Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance.
Am. J. Physiol. Heart Circ. Physiol., 2015 Mar 15 , 308 (H637-50).

15

So K et al. Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models.
J. Pharmacol. Sci., 2015 Mar , 127 (237-43).

16

Lavorgna G et al. Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell.
Genom Data, 2015 Mar , 3 (4-5).

17

Cao QF et al. TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells.
Cancer Biother. Radiopharm., 2015 Mar , 30 (87-93).

18

Chung MK et al. The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia.
Neuroscience, 2015 Jun 25 , 297 (160-9).

19

Swarbrick JM et al. Designer small molecules to target calcium signalling.
Biochem. Soc. Trans., 2015 Jun , 43 (417-25).

20

Rosenbaum T Activators of TRPM2: Getting it right.
J. Gen. Physiol., 2015 Jun , 145 (485-7).

21

Ru X et al. Transient receptor potential channel M2 contributes to neointimal hyperplasia in vascular walls.
Biochim. Biophys. Acta, 2015 Jul , 1852 (1360-71).

22

Övey IS et al. Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: involvement of TRPM2 and TRPV1 channels.
Neuroscience, 2015 Jan 22 , 284 (225-33).

23

Lee CR et al. Inhibitory and excitatory neuromodulation by hydrogen peroxide: translating energetics to information.
J. Physiol. (Lond.), 2015 Jan 21 , ().

24

Köse SA et al. N-acetyl cysteine reduces oxidative toxicity, apoptosis, and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome.
Free Radic. Res., 2015 Feb 9 , (1-9).

25

Yürüker V et al. Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels.
Metab Brain Dis, 2015 Feb , 30 (223-31).

26

Alptekin M et al. Gene expressions of TRP channels in glioblastoma multiforme and relation with survival.
Tumour Biol., 2015 Dec , 36 (9209-13).

27

Jang Y et al. TRPM2, a Susceptibility Gene for Bipolar Disorder, Regulates Glycogen Synthase Kinase-3 Activity in the Brain.
J. Neurosci., 2015 Aug 26 , 35 (11811-23).

28

Zhang E et al. Brain transient receptor potential channels and stroke.
J. Neurosci. Res., 2015 Aug , 93 (1165-83).

29

Isman E et al. Effects of laser irradiation at different wavelengths (660, 810, 980, and 1064 nm) on transient receptor potential melastatin channels in an animal model of wound healing.
Lasers Med Sci, 2015 Apr 12 , ().

30

Tabur S et al. Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.
Eur Rev Med Pharmacol Sci, 2015 Apr , 19 (1388-97).

31

Aydin S et al. Alteration of serum and cardiac tissue adropin, copeptin, irisin and TRPM2 expressions in DOX treated male rats.
Biotech Histochem, 2015 Apr , 90 (197-205).

32

Mittal M et al. Novel role of reactive oxygen species-activated Trp melastatin channel-2 in mediating angiogenesis and postischemic neovascularization.
Arterioscler. Thromb. Vasc. Biol., 2015 Apr , 35 (877-87).

33

Rah SY et al. ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells.
Sci Rep, 2015 , 5 (9482).

34

Kühn FJ et al. Functional characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells.
Sci Rep, 2015 , 5 (8032).

35

Choi HJ et al. Astrocytes in the optic nerve head express putative mechanosensitive channels.
Mol. Vis., 2015 , 21 (749-66).

36

Tsukimoto M Purinergic Signaling Is a Novel Mechanism of the Cellular Response to Ionizing Radiation.
Biol. Pharm. Bull., 2015 , 38 (951-9).

37

Moosmann J et al. Novel loci for non-syndromic coarctation of the aorta in sporadic and familial cases.
PLoS ONE, 2015 , 10 (e0126873).

38

Nazıroğlu M et al. Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs.
Curr Neuropharmacol, 2015 , 13 (248-57).

39

Quillinan N et al. Sex Steroids Do Not Modulate TRPM2-Mediated Injury in Females following Middle Cerebral Artery Occlusion(1,2,3).
eNeuro, 2014 Nov-Dec , 1 ().

40

Dusmez D et al. Effect of verapamil and lidocaine on TRPM and NaV1.9 gene expressions in renal ischemia-reperfusion.
Transplant. Proc., 2014 Jan-Feb , 46 (33-9).

41

Shirakawa H et al. [Pathophysiology of immune cells during the progression of cerebral ischemic injury - involvement of TRPM2-mediated induction of iNOS in microglia/macrophage].
Nippon Yakurigaku Zasshi, 2014 Sep , 144 (104-9).

42

Ahn C et al. Regulation and localization of transient receptor potential melastatin 2 in rat uterus.
Reprod Sci, 2014 Oct , 21 (1288-95).

43

Yosida M et al. Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion.
Diabetes, 2014 Oct , 63 (3394-403).

44

Jang Y et al. TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain.
Pflugers Arch., 2014 Oct , 466 (1987-98).

45

Shimizu S et al. Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Eur. J. Pharmacol., 2014 Nov 5 , 742 (22-30).

46

Tóth B et al. Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating.
Proc. Natl. Acad. Sci. U.S.A., 2014 Nov 25 , 111 (16949-54).

47

Gao G et al. TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.
J. Clin. Invest., 2014 Nov , 124 (4989-5001).

48

Gelderblom M et al. Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke.
Stroke, 2014 Nov , 45 (3395-402).

49

Uchida K et al. The role of TRPM2 in pancreatic β-cells and the development of diabetes.
Cell Calcium, 2014 Nov , 56 (332-9).

50

Lu S et al. Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.
Microcirculation, 2014 Nov , 21 (754-60).

51

Demir T et al. Evaluation of TRPM (transient receptor potential melastatin) genes expressions in myocardial ischemia and reperfusion.
Mol. Biol. Rep., 2014 May , 41 (2845-9).

52

Akpinar A et al. Agomelatine and duloxetine synergistically modulates apoptotic pathway by inhibiting oxidative stress triggered intracellular calcium entry in neuronal PC12 cells: role of TRPM2 and voltage-gated calcium channels.
J. Membr. Biol., 2014 May , 247 (451-9).

53

Nazıroğlu M et al. Modulation of oxidative stress and Ca(2+) mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum.
Neuroscience, 2014 Mar 28 , 263 (27-35).

54

Miller BA et al. TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.
J. Biol. Chem., 2014 Mar 14 , 289 (7615-29).

55

Tran VT et al. Mechanotransduction channels of the trabecular meshwork.
Curr. Eye Res., 2014 Mar , 39 (291-303).

56

Nazıroğlu M et al. Hypericum perforatum modulates apoptosis and calcium mobilization through voltage-gated and TRPM2 calcium channels in neutrophil of patients with Behcet's disease.
J. Membr. Biol., 2014 Mar , 247 (253-62).

57

Gerace E et al. PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca(2+)-permeable AMPA receptors.
Neurobiol. Dis., 2014 Jun 20 , ().

58

Orfanelli U et al. Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer.
Oncogene, 2014 Jun 16 , ().

59

Roberge S et al. TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.
Cardiovasc. Res., 2014 Jul 1 , 103 (90-9).

60

Hecquet CM et al. Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis.
Circ. Res., 2014 Jan 31 , 114 (469-79).

61

Miyake T et al. TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia.
Biochem. Biophys. Res. Commun., 2014 Feb 7 , 444 (212-7).

62

Kheradpezhouh E et al. TRPM2 channels mediate acetaminophen-induced liver damage.
Proc. Natl. Acad. Sci. U.S.A., 2014 Feb 25 , 111 (3176-81).

63

Ru X et al. TRPM2: a multifunctional ion channel for oxidative stress sensing.
Sheng Li Xue Bao, 2014 Feb 25 , 66 (7-15).

64

Chen SJ et al. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.
J. Biol. Chem., 2014 Dec 26 , 289 (36284-302).

65

Yamaguchi S et al. Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity.
J. Biol. Chem., 2014 Dec 19 , 289 (35265-82).

66

Kozai D et al. Redox regulation of transient receptor potential channels.
Antioxid. Redox Signal., 2014 Aug 20 , 21 (971-86).

67

Etem EO et al. The effects of hydrated C(60) fullerene on gene expression profile of TRPM2 and TRPM7 in hyperhomocysteinemic mice.
J. Recept. Signal Transduct. Res., 2014 Aug , 34 (317-24).

68

Qian X et al. Transient receptor potential melastatin 2 protects mice against polymicrobial sepsis by enhancing bacterial clearance.
Anesthesiology, 2014 Aug , 121 (336-51).

69

Ishii M et al. Involvement of TRPM2 and L-type Ca²⁺ channels in Ca²⁺ entry and cell death induced by hydrogen peroxide in rat β-cell line RIN-5F.
J Toxicol Sci, 2014 Apr , 39 (199-209).

70

Faouzi M et al. TRPM2.
Handb Exp Pharmacol, 2014 , 222 (403-26).

71

Baez D et al. Gating of thermally activated channels.
Curr Top Membr, 2014 , 74 (51-87).

72

Yu W et al. Inactivation of TRPM2 channels by extracellular divalent copper.
PLoS ONE, 2014 , 9 (e112071).

73

Park L et al. The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.
Nat Commun, 2014 , 5 (5318).

74

Braun AP A novel disease connection for TRPM2 channels.
Channels (Austin), 2014 , 8 (475-6).

75

Shimizu S et al. TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters).
Handb Exp Pharmacol, 2014 , 223 (767-94).

76

Nakagawa T et al. [Roles of transient receptor potential melastatin 2 expressed on immune cells in neuropathic pain].
Yakugaku Zasshi, 2014 , 134 (379-86).

77

Ye M et al. TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia.
Cell Death Dis, 2014 , 5 (e1541).

78

Nakayama S et al. Sexually dimorphic response of TRPM2 inhibition following cardiac arrest-induced global cerebral ischemia in mice.
J. Mol. Neurosci., 2013 Sep , 51 (92-8).

79

Alim I et al. Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death.
J. Neurosci., 2013 Oct 30 , 33 (17264-77).

80

Kim TK et al. Lys1110 of TRPM2 is critical for channel activation.
Biochem. J., 2013 Nov 1 , 455 (319-27).

81

Nakagawa T et al. [Involvement of spinally-infiltrated immune cells in peripheral nerve injury-induced neuropathic pain: roles of TRPM2].
Nippon Yakurigaku Zasshi, 2013 Nov , 142 (215-20).

82

Homma Y et al. Increased mRNA expression of genes involved in pronociceptive inflammatory reactions in bladder tissue of interstitial cystitis.
J. Urol., 2013 May 28 , ().

83

Knowles H et al. The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation.
Immunol. Res., 2013 Mar , 55 (241-8).

84

Shimizu T et al. Androgen and PARP-1 regulation of TRPM2 channels after ischemic injury.
J. Cereb. Blood Flow Metab., 2013 Jun 26 , ().

85

Roedding AS et al. Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder.
Brain Res., 2013 Jun 23 , 1517 (16-27).

86

Masumoto K et al. Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage.
Biochim. Biophys. Acta, 2013 Jun , 1830 (3382-90).

87

Zou J et al. A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.
Am. J. Physiol., Cell Physiol., 2013 Jul 1 , 305 (C61-9).

88

Simon F et al. Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans.
Cell. Signal., 2013 Jul , 25 (1614-24).

89

Oda S et al. TRPM2 contributes to antigen-stimulated Ca²⁺ influx in mucosal mast cells.
Pflugers Arch., 2013 Jul , 465 (1023-30).

90

Chen SJ et al. Role of TRPM2 in Cell Proliferation and Susceptibility to Oxidative Stress.
Am. J. Physiol., Cell Physiol., 2013 Jan 9 , ().

91

Hiroi H et al. Expression and regulation of transient receptor potential cation channel, subfamily M, member 2 (TRPM2) in human endometrium.
Mol. Cell. Endocrinol., 2013 Jan 30 , 365 (146-52).

92

Lee CR et al. TRPM2 channels are required for NMDA-induced burst firing and contribute to H(2)O(2)-dependent modulation in substantia nigra pars reticulata GABAergic neurons.
J. Neurosci., 2013 Jan 16 , 33 (1157-68).

93

Hiroi T et al. Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury.
Cardiovasc. Res., 2013 Feb 1 , 97 (271-81).

94

Korthuis RJ et al. TRPing up reperfusion: neutrophil TRPM2 channels exacerbate necrosis and contractile dysfunction in post-ischaemic myocardium.
Cardiovasc. Res., 2013 Feb 1 , 97 (197-9).

95

Nazıroğlu M et al. Selenium modulates oxidative stress-induced TRPM2 cation channel currents in transfected Chinese hamster ovary cells.
Basic Clin. Pharmacol. Toxicol., 2013 Feb , 112 (96-102).

96

Schulze A et al. Apomorphine is a bimodal modulator of TRPA1 channels.
Mol. Pharmacol., 2013 Feb , 83 (542-51).

97

Moreau C et al. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.
J. Med. Chem., 2013 Dec 27 , 56 (10079-102).

98

Nazıroğlu M et al. Vitamin E modulates oxidative stress and protein kinase C activator (PMA)-induced TRPM2 channel gate in dorsal root ganglion of rats.
J. Bioenerg. Biomembr., 2013 Dec , 45 (541-9).

99

Naziroglu M et al. Role of TRPM2 cation channels in dorsal root ganglion of rats after experimental spinal cord injury.
Muscle Nerve, 2013 Dec , 48 (945-50).

100

Miller BA et al. The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury.
Am. J. Physiol. Heart Circ. Physiol., 2013 Apr 1 , 304 (H1010-22).

101

Xu C et al. Association of the iPLA2β gene with bipolar disorder and assessment of its interaction with TRPM2 gene polymorphisms.
Psychiatr. Genet., 2013 Apr , 23 (86-9).

102

Vandewauw I et al. Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse.
BMC Neurosci, 2013 , 14 (21).

103

Liu X et al. Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction.
Nat Commun, 2013 , 4 (1515).

104

Sumoza-Toledo A et al. TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice.
J Inflamm (Lond), 2013 , 10 (19).

105

Zhong Z et al. TRPM2 links oxidative stress to NLRP3 inflammasome activation.
Nat Commun, 2013 , 4 (1611).

106

Bianchetti E et al. Mechanisms underlying cell death in ischemia-like damage to the rat spinal cord in vitro.
Cell Death Dis, 2013 , 4 (e707).

107

Fairbanks SL et al. Sex stratified neuronal cultures to study ischemic cell death pathways.
J Vis Exp, 2013 , ().

108

Isami K et al. Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model.
PLoS ONE, 2013 , 8 (e66410).

109

Xu R et al. Oxidative stress mediates the disruption of airway epithelial tight junctions through a TRPM2-PLCγ1-PKCα signaling pathway.
Int J Mol Sci, 2013 , 14 (9475-86).

110

Guo H et al. Role of TRPM in melanocytes and melanoma.
Exp. Dermatol., 2012 Sep , 21 (650-4).

111

Wyrsch P et al. Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).
Mol. Cell. Biol., 2012 Sep , 32 (3541-53).

112

Amer MS et al. Inhibition of endothelial cell Ca(2+) entry and Transient Receptor Potential channels by Sigma-1 receptor ligands.
Br. J. Pharmacol., 2012 Nov 2 , ().

113

Verma S et al. TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death.
Neurosci. Lett., 2012 Nov 14 , 530 (41-6).

114

Chen GL et al. Pharmacological comparison of novel synthetic fenamate analogues with econazole and 2-APB on the inhibition of TRPM2 channels.
Br. J. Pharmacol., 2012 Nov , 167 (1232-43).

115

Özgül C et al. TRPM2 channel protective properties of N-acetylcysteine on cytosolic glutathione depletion dependent oxidative stress and Ca2+ influx in rat dorsal root ganglion.
Physiol. Behav., 2012 May 15 , 106 (122-8).

116

Haraguchi K et al. TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice.
J. Neurosci., 2012 Mar 14 , 32 (3931-41).

117

Numata T et al. The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation.
J. Physiol. (Lond.), 2012 Mar 1 , 590 (1121-38).

118

Roedding AS et al. Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder.
Bipolar Disord, 2012 Mar , 14 (151-61).

119

Zeng B et al. Divalent copper is a potent extracellular blocker for TRPM2 channel.
, 2012 Jun 27 , ().

120

Magnone M et al. NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.
J. Biol. Chem., 2012 Jun 15 , 287 (21067-81).

121

Nazıroğlu M Molecular role of catalase on oxidative stress-induced Ca(2+) signaling and TRP cation channel activation in nervous system.
J. Recept. Signal Transduct. Res., 2012 Jun , 32 (134-41).

122

Yu PL et al. A novel fluorescent cell membrane-permeable caged cyclic ADP-ribose analogue.
J. Biol. Chem., 2012 Jul 13 , 287 (24774-83).

123

Laub KR et al. Comparing ion conductance recordings of synthetic lipid bilayers with cell membranes containing TRP channels.
, 2012 Jan 28 , ().

124

Ham HY et al. Sulfur mustard primes human neutrophils for increased degranulation and stimulates cytokine release via TRPM2/p38 MAPK signaling.
Toxicol. Appl. Pharmacol., 2012 Jan 1 , 258 (82-8).

125

Di A et al. The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.
Nat. Immunol., 2012 Jan , 13 (29-34).

126

Xu SZ et al. Activation of TRPC cationic channels by mercurial compounds confers the cytotoxicity of mercury exposure.
Toxicol. Sci., 2012 Jan , 125 (56-68).

127

Nazıroğlu M et al. Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat.
Physiol. Behav., 2012 Feb 1 , 105 (683-92).

128

Pang B et al. Differential pathways for calcium influx activated by concanavalin A and CD3 stimulation in Jurkat T cells.
Pflugers Arch., 2012 Feb , 463 (309-18).

129

Yeung-Yam-Wah V et al. Arachidonic acid mobilizes Ca2+ from the endoplasmic reticulum and an acidic store in rat pancreatic β cells.
Cell Calcium, 2012 Feb , 51 (140-8).

130

Katano M et al. The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.
Cell Calcium, 2012 Feb , 51 (179-85).

131

Kayan M et al. Non-ionic contrast media induces oxidative stress and apoptosis through Ca²⁺ influx in human neutrophils.
J. Membr. Biol., 2012 Dec , 245 (833-40).

132

Premkumar LS et al. TRP channels and analgesia.
Life Sci., 2012 Aug 14 , ().

133

Tóth B et al. Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.
Proc. Natl. Acad. Sci. U.S.A., 2012 Aug 14 , 109 (13440-5).

134

Hardaker L et al. The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases.
, 2012 Apr 4 , 13 (30).

135

Zhang Z et al. TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.
Am. J. Physiol. Endocrinol. Metab., 2012 Apr , 302 (E807-16).

136

Wang T et al. Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation.
Part Fibre Toxicol, 2012 , 9 (35).

137

Melzer N et al. TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.
PLoS ONE, 2012 , 7 (e47617).

138

Winking M et al. Importance of a conserved sequence motif in transmembrane segment S3 for the gating of human TRPM8 and TRPM2.
PLoS ONE, 2012 , 7 (e49877).

139

Yu P et al. A cell permeable NPE caged ADP-ribose for studying TRPM2.
PLoS ONE, 2012 , 7 (e51028).

140

Belrose JC et al. Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.
Mol Brain, 2012 , 5 (11).

141

Takahashi K et al. Hypoxic stress induces transient receptor potential melastatin 2 (TRPM2) channel expression in adult rat cardiac fibroblasts.
J. Pharmacol. Sci., 2012 , 118 (186-97).

142

Sun L et al. Role of TRPM2 in H(2)O(2)-Induced Cell Apoptosis in Endothelial Cells.
PLoS ONE, 2012 , 7 (e43186).

143

Uchida K et al. TRPM2 modulates insulin secretion in pancreatic β-cells.
Islets, 2011 Jul-Aug , 3 (209-11).

144

Takahashi N et al. Roles of TRPM2 in oxidative stress.
Cell Calcium, 2011 Sep , 50 (279-87).

145

Sumoza-Toledo A et al. Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release.
FASEB J., 2011 Oct , 25 (3529-42).

146

Zierler S et al. Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels.
J. Biol. Chem., 2011 Nov 11 , 286 (39328-35).

147

Yang W et al. Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore.
, 2011 May 20 , ().

148

Jia J et al. Sex differences in neuroprotection provided by inhibition of TRPM2 channels following experimental stroke.
, 2011 May 18 , ().

149

Mrejeru A et al. Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta.
J. Physiol. (Lond.), 2011 May 15 , 589 (2497-514).

150

Jiang LH et al. Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.
Curr Drug Targets, 2011 May , 12 (724-36).

151

Yamamoto S et al. [Function of TRPM2 as a Ca(2+)-release channel in β cells].
Nippon Yakurigaku Zasshi, 2011 May , 137 (207-11).

152

Nazıroğlu M et al. Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone.
J. Membr. Biol., 2011 May , 241 (69-75).

153

Nazıroğlu M TRPM2 channel membrane currents in primary rat megakaryocytes were activated by the agonist ADP-ribose but not oxidative stress.
J. Membr. Biol., 2011 May , 241 (51-7).

154

Nazıroğlu M TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
Neurochem. Res., 2011 Mar , 36 (355-66).

155

Knowles H et al. Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes.
, 2011 Jun 27 , ().

156

Park KS et al. Identification and functional characterization of ion channels in CD34(+) hematopoietic stem cells from human peripheral blood.
, 2011 Jun 1 , ().

157

Majeed Y et al. Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels.
Mol. Pharmacol., 2011 Jun , 79 (1023-30).

158

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