Kv7.2

1

Gafar H et al. Membrane coordination of receptors and channels mediating the inhibition of neuronal ion currents by ADP.
Purinergic Signal., 2016 May 12 , ().

2

Dai G et al. Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P2 levels.
Proc. Natl. Acad. Sci. U.S.A., 2016 Jun 7 , 113 (E3290-9).

3

Kumar M et al. Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators.
Mol. Pharmacol., 2016 Jun , 89 (667-77).

4

Schütze S et al. KCNQ Potassium Channels Modulate Sensitivity of Skin D-hair Mechanoreceptors.
J. Biol. Chem., 2016 Jan 5 , ().

5

Syeda R et al. The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.
J. Biol. Chem., 2016 Feb 5 , 291 (2931-7).

6

Kim KX et al. Maturation of NaV and KV Channel Topographies in the Auditory Nerve Spike Initiator before and after Developmental Onset of Hearing Function.
J. Neurosci., 2016 Feb 17 , 36 (2111-8).

7

Benned-Jensen T et al. Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.
J. Neurosci., 2016 Feb 17 , 36 (2261-6).

8

Siloni S et al. Regulation of the neuronal KCNQ2 channel by Src--a dual rearrangement of the cytosolic termini underlies bidirectional regulation of gating.
J. Cell. Sci., 2015 Sep 15 , 128 (3489-501).

9

Alberdi A et al. Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly de-stabilizing epileptogenic mutation.
J. Cell. Sci., 2015 Sep 10 , ().

10

Provence A et al. The Novel KV7.2/KV7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility.
J. Pharmacol. Exp. Ther., 2015 Sep , 354 (290-301).

11

Samanta D et al. Myoclonic epilepsy evolved into West syndrome: a patient with a novel de novo KCNQ2 mutation.
Acta Neurol Belg, 2015 Sep , 115 (475-8).

12

Reid ES et al. Seizures Due to a KCNQ2 Mutation: Treatment with Vitamin B6.
JIMD Rep, 2015 Oct 8 , ().

13

Jiang L et al. Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channel via CRMP-2 mediated pathway.
J. Cell. Sci., 2015 Oct 7 , ().

14

Santella L et al. Assisted yes, but where do we draw the line?
Reprod. Biomed. Online, 2015 Oct , 31 (476-8).

15

Milh M et al. Variable clinical expression in patients with mosaicism for KCNQ2 mutations.
Am. J. Med. Genet. A, 2015 Oct , 167A (2314-8).

16

Barrese V et al. Protective role of Kv7 channels in oxygen and glucose deprivation-induced damage in rat caudate brain slices.
J. Cereb. Blood Flow Metab., 2015 Oct , 35 (1593-600).

17

Davoren JE et al. Discovery of a novel Kv7 channel opener as a treatment for epilepsy.
Bioorg. Med. Chem. Lett., 2015 Nov 1 , 25 (4941-4).

18

Pisano T et al. Early and effective treatment of KCNQ2 encephalopathy.
Epilepsia, 2015 May , 56 (685-91).

19

Mercimek-Mahmutoglu S et al. Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.
Epilepsia, 2015 May , 56 (707-16).

20

Pribaz E et al. The Jack Pribaz Foundation and KCNQ2.org.
Epilepsia, 2015 May , 56 (682-4).

21

Kaminsky Z et al. DNA methylation and expression of KCNQ3 in bipolar disorder.
Bipolar Disord, 2015 Mar , 17 (150-9).

22

Kalappa BI et al. Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitus.
J. Neurosci., 2015 Jun 10 , 35 (8829-42).

23

Okumura A et al. Phenotypes of children with 20q13.3 microdeletion affecting KCNQ2 and CHRNA4.
Epileptic Disord, 2015 Jun , 17 (165-71).

24

Mills TA et al. Activation of KV7 channels stimulates vasodilatation of human placental chorionic plate arteries.
Placenta, 2015 Jun , 36 (638-44).

25

Xu M et al. An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels.
J. Biol. Chem., 2015 Jul 3 , 290 (16619-32).

26

Grinton BE et al. Familial neonatal seizures in 36 families: Clinical and genetic features correlate with outcome.
Epilepsia, 2015 Jul , 56 (1071-80).

27

Martinello K et al. Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells.
Neuron, 2015 Jan 21 , 85 (346-63).

28

Lemmerhirt CJ et al. Oxidation potentials of N-modified derivatives of the analgesic flupirtine linked to potassium KV 7 channel opening activity but not hepatocyte toxicity.
ChemMedChem, 2015 Feb , 10 (368-79).

29

Boutry-Kryza N et al. Molecular characterization of a cohort of 73 patients with infantile spasms syndrome.
Eur J Med Genet, 2015 Feb , 58 (51-8).

30

Miceli F et al. A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability.
Epilepsia, 2015 Feb , 56 (e15-20).

31

Hashimoto R et al. Uncompacted Myelin Lamellae and Nodal Ion Channel Disruption in POEMS Syndrome.
J. Neuropathol. Exp. Neurol., 2015 Dec , 74 (1127-36).

32

Laumet G et al. G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.
Nat. Neurosci., 2015 Dec , 18 (1746-55).

33

Wang J et al. Functional analysis of potassium channels in Kv7.2 G271V mutant causing early onset familial epilepsy.
Brain Res., 2015 Aug 7 , 1616 (112-22).

34

Gomis-Perez C et al. An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.
J. Cell. Sci., 2015 Aug 15 , 128 (3155-63).

35

Li C et al. Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron.
Neuropharmacology, 2015 Aug , 95 (154-67).

36

Abidi A et al. A recurrent KCNQ2 pore mutation causing early onset epileptic encephalopathy has a moderate effect on M current but alters subcellular localization of Kv7 channels.
Neurobiol. Dis., 2015 Aug , 80 (80-92).

37

Figueiro-Silva J et al. Neuronal pentraxin 1 negatively regulates excitatory synapse density and synaptic plasticity.
J. Neurosci., 2015 Apr 8 , 35 (5504-21).

38

Fidzinski P et al. KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Nat Commun, 2015 , 6 (6254).

39

Zhang F et al. Inhibition of Kv7/M Channel Currents by the Local Anesthetic Chloroprocaine.
Pharmacology, 2015 , 96 (124-30).

40

Mayordomo-Cava J et al. Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus.
PLoS ONE, 2015 , 10 (e0134385).

41

Kim RY et al. Atomic basis for therapeutic activation of neuronal potassium channels.
Nat Commun, 2015 , 6 (8116).

42

Svalø J et al. Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
PLoS ONE, 2015 , 10 (e0117350).

43

Shimatani Y et al. Abnormal gating of axonal slow potassium current in cramp-fasciculation syndrome.
Clin Neurophysiol, 2014 Sep 28 , ().

44

Cuppoletti J et al. Differentiation between human ClC-2 and CFTR Cl- channels with pharmacological agents.
Am. J. Physiol., Cell Physiol., 2014 Sep 1 , 307 (C479-92).

45

Allen NM et al. The variable phenotypes of KCNQ-related epilepsy.
Epilepsia, 2014 Sep , 55 (e99-105).

46

Zerem A et al. Paternal germline mosaicism of a SCN2A mutation results in Ohtahara syndrome in half siblings.
Eur. J. Paediatr. Neurol., 2014 Sep , 18 (567-71).

47

Grigorov A et al. Kv7 potassium channel subunits and M currents in cultured hippocampal interneurons.
Pflugers Arch., 2014 Sep , 466 (1747-58).

48

King CH et al. Kv7.2 regulates the function of peripheral sensory neurons.
J. Comp. Neurol., 2014 Oct 1 , 522 (3262-80).

49

Li C et al. KCNQ/Kv7 channel activator flupirtine protects against acute stress-induced impairments of spatial memory retrieval and hippocampal LTP in rats.
Neuroscience, 2014 Nov 7 , 280 (19-30).

50

Frolov RV et al. Celecoxib and ion channels: a story of unexpected discoveries.
Eur. J. Pharmacol., 2014 May 5 , 730 (61-71).

51

Battefeld A et al. Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons.
J. Neurosci., 2014 Mar 5 , 34 (3719-32).

52

Brueggemann LI et al. KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways.
Am. J. Physiol. Lung Cell Mol. Physiol., 2014 Mar 15 , 306 (L476-86).

53

Soldovieri MV et al. Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: first evidence for an altered channel regulation by syntaxin-1A.
Hum. Mutat., 2014 Mar , 35 (356-67).

54

Orhan G et al. Dominant-negative effects of KCNQ2 mutations are associated with epileptic encephalopathy.
Ann. Neurol., 2014 Mar , 75 (382-94).

55

Jepps TA et al. Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370.
Br. J. Pharmacol., 2014 Jun 9 , ().

56

Dickson EJ et al. Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jun 3 , 111 (E2281-90).

57

Brueggemann LI et al. Differential Activation of Vascular Smooth Muscle Kv7.4, Kv7.5, and Kv7.4/7.5 Channels by ML213 and ICA-069673.
Mol. Pharmacol., 2014 Jun 18 , ().

58

Martin HC et al. Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis.
Hum. Mol. Genet., 2014 Jun 15 , 23 (3200-11).

59

Numis AL et al. KCNQ2 encephalopathy: delineation of the electroclinical phenotype and treatment response.
Neurology, 2014 Jan 28 , 82 (368-70).

60

Liu W et al. Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons.
Mol. Cell. Neurosci., 2014 Jan , 58 (40-52).

61

Li P et al. The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.
J. Pharmacol. Exp. Ther., 2014 Dec , 351 (596-604).

62

Gourgy-Hacohen O et al. Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.
J. Gen. Physiol., 2014 Dec , 144 (513-27).

63

Soh H et al. Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.
J. Neurosci., 2014 Apr 9 , 34 (5311-21).

64

Kang S et al. Channel-anchored protein kinase CK2 and protein phosphatase 1 reciprocally regulate KCNQ2-containing M-channels via phosphorylation of calmodulin.
J. Biol. Chem., 2014 Apr 18 , 289 (11536-44).

65

Moreau A et al. Biophysics, pathophysiology, and pharmacology of ion channel gating pores.
Front Pharmacol, 2014 , 5 (53).

66

Dalen Meurs-van der Schoor C et al. Severe Neonatal Epileptic Encephalopathy and KCNQ2 Mutation: Neuropathological Substrate?
Front Pediatr, 2014 , 2 (136).

67

Hille B et al. Dynamic metabolic control of an ion channel.
Prog Mol Biol Transl Sci, 2014 , 123 (219-47).

68

Maljevic S et al. Potassium channel genes and benign familial neonatal epilepsy.
Prog. Brain Res., 2014 , 213 (17-53).

69

Achary PG Simplified molecular input line entry system-based optimal descriptors: QSAR modelling for voltage-gated potassium channel subunit Kv7.2.
SAR QSAR Environ Res, 2014 , 25 (73-90).

70

Alaimo A et al. Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.
PLoS ONE, 2014 , 9 (e86711).

71

Wu C et al. Kcnq1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish.
BMC Physiol., 2014 , 14 (1).

72

Tomonoh Y et al. The kick-in system: a novel rapid knock-in strategy.
PLoS ONE, 2014 , 9 (e88549).

73

Blom SM et al. From pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl group.
PLoS ONE, 2014 , 9 (e100209).

74

Kole MH et al. Axonal Kv7.2/7.3 channels: caught in the act.
Channels (Austin), 2014 , 8 (288-9).

75

Cavaretta JP et al. Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit.
PLoS ONE, 2014 , 9 (e103655).

76

Soh H et al. Cortical KCNQ2/3 channels; insights from knockout mice.
Channels (Austin), 2014 , 8 (389-90).

77

[To the mechanisms of antiarrhythmic action of Allapinine].
Bioorg. Khim., 2013 Jan-Feb , 39 (105-16).

78

Svalø J et al. Bladder contractility is modulated by Kv7 channels in pig detrusor.
Eur. J. Pharmacol., 2013 Sep 5 , 715 (312-20).

79

Reilly JM et al. Kv7/M-type potassium channels in rat skin keratinocytes.
Pflugers Arch., 2013 Sep , 465 (1371-81).

80

Kornilov P et al. Channel gating pore: a new therapeutic target.
Cell Res., 2013 Sep , 23 (1067-8).

81

Li P et al. The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands.
Cell Res., 2013 Sep , 23 (1106-18).

82

Vetter I et al. Amplified cold transduction in native nociceptors by M-channel inhibition.
J. Neurosci., 2013 Oct 16 , 33 (16627-41).

83

Hu HN et al. Discovery of a retigabine derivative that inhibits KCNQ2 potassium channels.
Acta Pharmacol. Sin., 2013 Oct , 34 (1359-66).

84

Salyer SA et al. Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells.
Biochim. Biophys. Acta, 2013 Oct , 1832 (1734-43).

85

Li X et al. Millimeter wave promotes the synthesis of extracellular matrix and the proliferation of chondrocyte by regulating the voltage-gated K(+) channel.
J. Bone Miner. Metab., 2013 Nov 8 , ().

86

Weckhuysen S et al. Extending the KCNQ2 encephalopathy spectrum: clinical and neuroimaging findings in 17 patients.
Neurology, 2013 Nov 5 , 81 (1697-703).

87

Wu YJ et al. Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain.
Bioorg. Med. Chem. Lett., 2013 Nov 15 , 23 (6188-91).

88

Walleigh DJ et al. Ring chromosome 20: a pediatric potassium channelopathy responsive to treatment with ezogabine.
Pediatr. Neurol., 2013 Nov , 49 (368-9).

89

Morhenn VB et al. Psoriatic keratinocytes are resistant to tumor necrosis factor alpha's induction of mRNA for the NMDA-R2C subunit.
Exp. Dermatol., 2013 Nov , 22 (750-1).

90

Zhou P et al. Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 May 21 , 110 (8726-31).

91

Cuppoletti J et al. Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents.
Cell Biochem. Biophys., 2013 May , 66 (53-63).

92

Falkenburger BH et al. Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signaling.
J. Gen. Physiol., 2013 May , 141 (537-55).

93

Dickson EJ et al. Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling.
J. Gen. Physiol., 2013 May , 141 (521-35).

94

Fister P et al. Benign familial neonatal convulsions caused by mutation in KCNQ3, exon 6: a European case.
Eur. J. Paediatr. Neurol., 2013 May , 17 (308-10).

95

Zheng Q et al. Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model.
Pain, 2013 Mar , 154 (434-48).

96

Boehlen A et al. The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential.
Br. J. Pharmacol., 2013 Mar , 168 (1182-200).

97

Zara F et al. Genetic testing in benign familial epilepsies of the first year of life: clinical and diagnostic significance.
Epilepsia, 2013 Mar , 54 (425-36).

98

Li P et al. The ethylene bis-dithiocarbamate fungicide Mancozeb activates voltage-gated KCNQ2 potassium channel.
Toxicol. Lett., 2013 Jun 7 , 219 (211-7).

99

Sander SE et al. The K(V)7.2/3 preferring channel opener ICA 27243 attenuates L-DOPA-induced dyskinesia in hemiparkinsonian rats.
Neurosci. Lett., 2013 Jun 17 , 545 (59-63).

100

Li S et al. Pathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jun 11 , 110 (9980-5).

101

Füll Y et al. A conserved threonine in the S1-S2 loop of KV7.2 and K V7.3 channels regulates voltage-dependent activation.
Pflugers Arch., 2013 Jun , 465 (797-804).

102

Serino D et al. Video/EEG findings in a KCNQ2 epileptic encephalopathy: a case report and revision of literature data.
Epileptic Disord, 2013 Jun , 15 (158-65).

103

Kato M et al. Clinical spectrum of early onset epileptic encephalopathies caused by KCNQ2 mutation.
Epilepsia, 2013 Jul , 54 (1282-7).

104

Telezhkin V et al. A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.
Pflugers Arch., 2013 Jul , 465 (945-53).

105

Fretwell LV et al. Cardiovascular responses to retigabine in conscious rats--under normotensive and hypertensive conditions.
Br. J. Pharmacol., 2013 Jul , 169 (1279-89).

106

Alaimo A et al. Cooperativity between calmodulin-binding sites in Kv7.2 channels.
J. Cell. Sci., 2013 Jan 1 , 126 (244-53).

107

Yoshimura S et al. Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin 4 antibody status.
J. Neurol. Neurosurg. Psychiatr., 2013 Jan , 84 (29-34).

108

Saadeldin IY et al. Novel KCNQ2 mutation in a large Emirati family with benign familial neonatal seizures.
Pediatr. Neurol., 2013 Jan , 48 (63-6).

109

Miranda P et al. The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current.
J. Neurosci., 2013 Feb 6 , 33 (2684-96).

110

Zhang XF et al. Development and validation of a medium-throughput electrophysiological assay for KCNQ2/3 channel openers using QPatch HT.
Assay Drug Dev Technol, 2013 Feb , 11 (17-24).

111

Zhang Q et al. Dynamic PIP2 interactions with voltage sensor elements contribute to KCNQ2 channel gating.
Proc. Natl. Acad. Sci. U.S.A., 2013 Dec 10 , 110 (20093-8).

112

Khanamiri S et al. Contribution of Kv7 channels to basal coronary flow and active response to ischemia.
Hypertension, 2013 Dec , 62 (1090-7).

113

Lee YH et al. Pathway analysis of a genome-wide association study in schizophrenia.
Gene, 2013 Aug 1 , 525 (107-15).

114

Maslarova A et al. Increased susceptibility to acetylcholine in the entorhinal cortex of pilocarpine-treated rats involves alterations in KCNQ channels.
Neurobiol. Dis., 2013 Aug , 56 (14-24).

115

Lichter-Peled A et al. Role of KCNQ2 and KCNQ3 genes in juvenile idiopathic epilepsy in Arabian foals.
Vet. J., 2013 Apr , 196 (57-63).

116

Judy JT et al. Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder.
Front Genet, 2013 , 4 (87).

117

Kosenko A et al. A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity.
PLoS ONE, 2013 , 8 (e82290).

118

Ferrer T et al. Tamoxifen inhibition of kv7.2/kv7.3 channels.
PLoS ONE, 2013 , 8 (e76085).

119

Dai X et al. Effects of estrogen on neuronal KCNQ2/3 channels expressed in PC-12 cells.
Biol. Pharm. Bull., 2013 , 36 (1583-6).

120

Robbins J et al. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
PLoS ONE, 2013 , 8 (e71809).

121

Afeli SA et al. Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle.
PLoS ONE, 2013 , 8 (e75875).

122

Cavaliere S et al. KCNQ channels regulate age-related memory impairment.
PLoS ONE, 2013 , 8 (e62445).

123

Milh M et al. Similar early characteristics but variable neurological outcome of patients with a de novo mutation of KCNQ2.
Orphanet J Rare Dis, 2013 , 8 (80).

124

Bennett V et al. Spectrin- and ankyrin-based membrane domains and the evolution of vertebrates.
Curr Top Membr, 2013 , 72 (1-37).

125

Glasgow SD et al. Muscarinic depolarization of layer II neurons of the parasubiculum.
PLoS ONE, 2013 , 8 (e58901).

126

Mi Y et al. The role of potassium channel activation in celecoxib-induced analgesic action.
PLoS ONE, 2013 , 8 (e54797).

127

Mattmann ME et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator.
Bioorg. Med. Chem. Lett., 2012 Sep 15 , 22 (5936-41).

128

Yang ZM et al. [Study on gene differential expressions of substance and energy metabolism in chronic superficial gastritis patients of Pi deficiency syndrome and of pi-wei hygropyrexia syndrome].
Zhongguo Zhong Xi Yi Jie He Za Zhi, 2012 Sep , 32 (1180-7).

129

Tomlinson SE et al. In vivo loss of slow potassium channel activity in individuals with benign familial neonatal epilepsy in remission.
Brain, 2012 Oct , 135 (3144-52).

130

Afawi Z et al. Benign neonatal sleep myoclonus: an autosomal dominant form not allelic to KCNQ2 or KCNQ3.
J. Child Neurol., 2012 Oct , 27 (1260-3).

131

Ishii A et al. KCNQ2 abnormality in BECTS: benign childhood epilepsy with centrotemporal spikes following benign neonatal seizures resulting from a mutation of KCNQ2.
Epilepsy Res., 2012 Nov , 102 (122-5).

132

Kosenko A et al. Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation.
, 2012 May 29 , ().

133

Telezhkin V et al. Structural requirements of membrane phospholipids for M-type potassium channel activation and binding.
J. Biol. Chem., 2012 Mar 23 , 287 (10001-12).

134

Hobiger K et al. Coupling of Ci-VSP modules requires a combination of structure and electrostatics within the linker.
Biophys. J., 2012 Mar 21 , 102 (1313-22).

135

Shah MM et al. HCN and K(V)7 (M-) channels as targets for epilepsy treatment.
, 2012 Mar 15 , ().

136

Pattnaik BR et al. Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium.
Am. J. Physiol., Cell Physiol., 2012 Mar , 302 (C821-33).

137

Choveau FS et al. Pore determinants of KCNQ3 K+ current expression.
Biophys. J., 2012 Jun 6 , 102 (2489-98).

138

Choveau FS et al. Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.
Biophys. J., 2012 Jun 6 , 102 (2499-509).

139

Ebner-Bennatan S et al. Multi-faceted modulation of K+ channels by protein tyrosine phosphatase epsilon tunes neuronal excitability.
, 2012 Jun 21 , ().

140

King CH et al. Kv7.5 is the primary Kv7 subunit expressed in C-fibers.
J. Comp. Neurol., 2012 Jun 15 , 520 (1940-50).

141

Van Poucke M et al. Experimental validation of in silico predicted KCNA1, KCNA2, KCNA6 and KCNQ2 genes for association studies of peripheral nerve hyperexcitability syndrome in Jack Russell Terriers.
Neuromuscul. Disord., 2012 Jun , 22 (558-65).

142

Li P et al. Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels.
Acta Pharmacol. Sin., 2012 Jun , 33 (728-36).

143

Blumkin L et al. Neonatal seizures associated with a severe neonatal myoclonus like dyskinesia due to a familial KCNQ2 gene mutation.
Eur. J. Paediatr. Neurol., 2012 Jul , 16 (356-60).

144

Telezhkin V et al. Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2.
J. Gen. Physiol., 2012 Jul , 140 (41-53).

145

Gunthorpe MJ et al. The mechanism of action of retigabine (ezogabine), a first-in-class K(+) channel opener for the treatment of epilepsy.
, 2012 Jan 5 , ().

146

Brueggemann LI et al. Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy.
Am. J. Physiol. Lung Cell Mol. Physiol., 2012 Jan , 302 (L120-32).

147

Hjaeresen ML et al. Time course and duration of changes in Kv7.2 and Kv11.1 mRNA expression in the hippocampus and piriform cortex following electroconvulsive stimulations.
Brain Stimul, 2012 Jan , 5 (55-60).

148

Weckhuysen S et al. KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.
Ann. Neurol., 2012 Jan , 71 (15-25).

149

Kamoun FF et al. Frontal motor seizure following non-convulsive status epilepticus in ring chromosome 20 syndrome.
Neurosciences (Riyadh), 2012 Jan , 17 (74-7).

150

Linley JE et al. M channel enhancers and physiological M channel block.
J. Physiol. (Lond.), 2012 Feb 15 , 590 (793-807).

151

Chege SW et al. Expression and function of KCNQ channels in larval zebrafish.
Dev Neurobiol, 2012 Feb , 72 (186-98).

152

Mahoney K et al. High incidence of pediatric idiopathic epilepsy is associated with familial and autosomal dominant disease in Eastern Newfoundland.
Epilepsy Res., 2012 Feb , 98 (140-7).

153

Zhang J et al. Activity-dependent transcriptional regulation of M-Type (Kv7) K(+) channels by AKAP79/150-mediated NFAT actions.
Neuron, 2012 Dec 20 , 76 (1133-46).

154

Mefford HC et al. Epilepsy due to 20q13.33 subtelomere deletion masquerading as pyridoxine-dependent epilepsy.
Am. J. Med. Genet. A, 2012 Dec , 158A (3190-5).

155

Cheung YY et al. Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent,
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