HCN2

1

Hayashi K et al. Green apatites: hydride ions, electrons and their interconversion in the crystallographic channel.
Phys Chem Chem Phys, 2016 Mar 9 , 18 (8186-95).

2

Deberg HA et al. Structure and Energetics of Allosteric Regulation of HCN2 Ion Channels by Cyclic Nucleotides.
J. Biol. Chem., 2016 Jan 1 , 291 (371-81).

3

Bruzauskaite I et al. Relevance of HCN2-expressing human mesenchymal stem cells for the generation of biological pacemakers.
Stem Cell Res Ther, 2016 , 7 (67).

4

Huang X et al. Age-associated expression of HCN channel isoforms in rat sinoatrial node.
Exp. Biol. Med. (Maywood), 2015 Sep 3 , ().

5

Luo P et al. Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region.
Neurobiol Learn Mem, 2015 Sep , 123 (72-83).

6

Li YD et al. Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.
Mol Med Rep, 2015 Sep , 12 (3243-8).

7

Liu Y et al. Pulsed Radiofrequency Treatment Enhances Dorsal Root Ganglion Expression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in a Rat Model of Neuropathic Pain.
J. Mol. Neurosci., 2015 Sep , 57 (97-105).

8

Li N et al. Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart.
Circ Arrhythm Electrophysiol, 2015 Oct , 8 (1219-27).

9

Hou B et al. Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes.
Neuroreport, 2015 Nov 11 , 26 (981-7).

10

O'Donnell AM et al. Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung's disease.
World J. Gastroenterol., 2015 May 14 , 21 (5635-40).

11

Mattusch C et al. Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments.
Anesthesiology, 2015 May , 122 (1047-59).

12

Challenor M et al. Prolonged glutamate excitotoxicity increases GluR1 immunoreactivity but decreases mRNA of GluR1 and associated regulatory proteins in dissociated rat retinae in vitro.
Biochimie, 2015 May , 112 (160-71).

13

Deberg HA et al. Structural Mechanism for the Regulation of HCN Ion Channels by the Accessory Protein TRIP8b.
Structure, 2015 Mar 4 , ().

14

Smith T et al. Increased Expression of HCN2 Channel Protein in L4 Dorsal Root Ganglion Neurons Following Axotomy of L5- and Inflammation of L4-Spinal Nerves in Rats.
Neuroscience, 2015 Mar 23 , ().

15

Oshita K et al. Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2.
J. Mol. Cell. Cardiol., 2015 Mar , 80 (81-9).

16

Zhou C et al. Hyperpolarization-activated cyclic nucleotide-gated channels may contribute to regional anesthetic effects of lidocaine.
Anesthesiology, 2015 Mar , 122 (606-18).

17

Yu HD et al. Spironolactone Regulates HCN Protein Expression Through Micro-RNA-1 in Rats With Myocardial Infarction.
J. Cardiovasc. Pharmacol., 2015 Jun , 65 (587-92).

18

Richards N et al. Contribution of hyperpolarization-activated channels to heat hypersensitivity and ongoing activity in the neuritis model.
Neuroscience, 2015 Jan 22 , 284 (87-98).

19

Yoshimoto R et al. Developmental increase in hyperpolarization-activated current regulates intrinsic firing properties in rat vestibular ganglion cells.
Neuroscience, 2015 Jan 22 , 284 (632-42).

20

Zhou M et al. Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure.
Prog. Neuropsychopharmacol. Biol. Psychiatry, 2015 Jan 2 , 56 (207-14).

21

Stoetzer C et al. Methadone is a local anaesthetic-like inhibitor of neuronal Na+ channels and blocks excitability of mouse peripheral nerves.
Br J Anaesth, 2015 Jan , 114 (110-20).

22

Li M et al. Effects of N-glycosylation on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Biochem. J., 2015 Feb 15 , 466 (77-84).

23

Pittoors F et al. HCN2 channels: a permanent open state and conductance changes.
J. Membr. Biol., 2015 Feb , 248 (67-81).

24

Galaz P et al. Advances in the pharmacology of lGICs auxiliary subunits.
Pharmacol. Res., 2015 Aug 7 , ().

25

Yang C et al. Decreased HCN2 expression in STN contributes to abnormal high-voltage spindles in the cortex and globus pallidus of freely moving rats.
Brain Res., 2015 Aug 27 , 1618 (17-28).

26

Djouhri L et al. Persistent hindlimb inflammation induces changes in activation properties of hyperpolarization-activated current (Ih) in rat C-fiber nociceptors in vivo.
Neuroscience, 2015 Aug 20 , 301 (121-33).

27

Cho YS et al. The expression of hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1) and HCN2 in the rat trigeminal ganglion, sensory root, and dental pulp.
Neuroscience, 2015 Apr 16 , 291 (15-25).

28

Kopp-Scheinpflug C et al. Nitric oxide selectively suppresses IH currents mediated by HCN1-containing channels.
J. Physiol. (Lond.), 2015 Apr 1 , 593 (1685-700).

29

DiFrancesco JC et al. Dysfunctional HCN ion channels in neurological diseases.
Front Cell Neurosci, 2015 , 6 (174).

30

Fürst O et al. Isoform dependent regulation of human HCN channels by cholesterol.
Sci Rep, 2015 , 5 (14270).

31

Günther A et al. Distinct expression patterns of HCN channels in HL-1 cardiomyocytes.
BMC Cell Biol., 2015 , 16 (18).

32

Seo H et al. Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.
Mol Brain, 2015 , 8 (13).

33

Baker EC et al. Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih.
PLoS ONE, 2015 , 10 (e0142730).

34

Kuppusamy M et al. A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
J. Clin. Endocrinol. Metab., 2014 Sep , 99 (E1765-73).

35

Li H et al. Dual effects of amiodarone on pacemaker currents in hypertrophied ventricular myocytes isolated from spontaneously hypertensive rats.
Clin. Exp. Pharmacol. Physiol., 2014 Sep , 41 (698-707).

36

Saponaro A et al. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Proc. Natl. Acad. Sci. U.S.A., 2014 Oct 7 , 111 (14577-82).

37

Yang YC et al. Dexmedetomidine produced analgesic effect via inhibition of HCN currents.
Eur. J. Pharmacol., 2014 Oct 5 , 740 (560-4).

38

Börger C et al. Resonance assignment of the ligand-free cyclic nucleotide-binding domain from the murine ion channel HCN2.
Biomol NMR Assign, 2014 Oct 17 , ().

39

Li CJ et al. Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion.
Mol. Neurobiol., 2014 Oct , 50 (704-20).

40

Sultana A et al. Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.
Exp. Neurol., 2014 Nov , 261 (802-11).

41

Boudkkazi S et al. Cornichon2 dictates the time course of excitatory transmission at individual hippocampal synapses.
Neuron, 2014 May 21 , 82 (848-58).

42

Möller S et al. Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
ACS Chem. Biol., 2014 May 16 , 9 (1128-37).

43

Gao W et al. State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygen.
J. Gen. Physiol., 2014 May , 143 (633-44).

44

Kodan A et al. Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc. Natl. Acad. Sci. U.S.A., 2014 Mar 18 , 111 (4049-54).

45

Klöckner U et al. Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains.
J. Physiol. (Lond.), 2014 Mar 15 , 592 (1199-211).

46

Wu T et al. [Neuropathic pain enhances expression of HCN2 channel in rat cerebrospinal fluid-contacting nucleus].
Sheng Li Xue Bao, 2014 Jun 25 , 66 (323-31).

47

Shields SD Conditional deletion of HCN2 from primary afferents uncovers the heterogeneity of inflammatory hypersensitivity.
Pain, 2014 Jun , 155 (1051-2).

48

Schnorr S et al. HCN2 channels account for mechanical (but not heat) hyperalgesia during long-standing inflammation.
Pain, 2014 Jun , 155 (1079-90).

49

Shah MM Cortical HCN channels: function, trafficking and plasticity.
J. Physiol. (Lond.), 2014 Jul 1 , 592 (2711-9).

50

Scheruebel S et al. I(f) blocking potency of ivabradine is preserved under elevated endotoxin levels in human atrial myocytes.
J. Mol. Cell. Cardiol., 2014 Jul , 72 (64-73).

51

Thon S et al. Avoiding the formation of vesicles by patch excision from Xenopus oocytes.
J. Neurosci. Methods, 2014 Jan 20 , ().

52

Calejo AI et al. Differences in the expression pattern of HCN isoforms among mammalian tissues: sources and implications.
Mol. Biol. Rep., 2014 Jan , 41 (297-307).

53

Gofman Y et al. Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel.
PLoS Comput. Biol., 2014 Dec , 10 (e1003976).

54

Dufour MA et al. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.
J. Neurosci. Res., 2014 Aug , 92 (981-99).

55

Powell KL et al. HCN channelopathy and cardiac electrophysiologic dysfunction in genetic and acquired rat epilepsy models.
Epilepsia, 2014 Apr , 55 (609-20).

56

Lenzini L et al. Lower expression of the TWIK-related acid-sensitive K+ channel 2 (TASK-2) gene is a hallmark of aldosterone-producing adenoma causing human primary aldosteronism.
J. Clin. Endocrinol. Metab., 2014 Apr , 99 (E674-82).

57

Horwitz GC et al. Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons.
J. Gen. Physiol., 2014 Apr , 143 (481-97).

58

Phillips AM et al. Spike-and-wave discharge mediated reduction in hippocampal HCN1 channel function associates with learning deficits in a genetic mouse model of epilepsy.
Neurobiol. Dis., 2014 Apr , 64 (30-5).

59

Sivagangabalan G et al. Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PLoS ONE, 2014 , 9 (e82179).

60

Li YD et al. Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation.
Med. Sci. Monit., 2014 , 20 (2292-7).

61

Lyashchenko AK et al. cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.
PLoS ONE, 2014 , 9 (e101236).

62

Williams TA et al. Somatic ATP1A1, ATP2B3, and KCNJ5 Mutations in Aldosterone-Producing Adenomas.
Hypertension, 2013 Sep 30 , ().

63

Li Y et al. [Adipose tissue-derived adult stem cells transfected with the gene of hyperpolarization-activated cyclic nucleotide-gated ion channel 2 differentiated into pacemaker-like cells].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2013 Sep , 29 (901-4).

64

Zuo GF et al. Capsazepine concentration dependently inhibits currents in HEK 293 cells mediated by human hyperpolarization-activated cyclic nucleotide-gated 2 and 4 channels.
Exp. Biol. Med. (Maywood), 2013 Sep , 238 (1055-61).

65

Kim YH et al. Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.
J. Gen. Physiol., 2013 Sep , 142 (207-23).

66

Nawathe PA et al. An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia.
J. Cardiovasc. Electrophysiol., 2013 Sep , 24 (1021-7).

67

Zhang XY et al. Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats.
Br. J. Pharmacol., 2013 Sep , 170 (156-69).

68

Carlson AE et al. Flavonoid regulation of HCN2 channels.
J. Biol. Chem., 2013 Oct 1 , ().

69

Thon S et al. Elementary functional properties of single HCN2 channels.
Biophys. J., 2013 Oct 1 , 105 (1581-9).

70

Zagidullin NSh et al. [Direct evidences of calcium traffic through pacemaker channel].
Ross Fiziol Zh Im I M Sechenova, 2013 Oct , 99 (1175-80).

71

Zagidullin NSh et al. [Direct evidences of calcium traffic through pacemaker channel].
Ross Fiziol Zh Im I M Sechenova, 2013 Oct , 99 (1175-80).

72

Monticone S et al. a Novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III.
J. Clin. Endocrinol. Metab., 2013 Nov , 98 (E1861-5).

73

Puljung MC et al. A secondary structural transition in the C-helix promotes gating of cyclic nucleotide-regulated ion channels.
J. Biol. Chem., 2013 May 3 , 288 (12944-56).

74

El Khoury N et al. Upregulation of the hyperpolarization-activated current increases pacemaker activity of the sinoatrial node and heart rate during pregnancy in mice.
Circulation, 2013 May 21 , 127 (2009-20).

75

Boink GJ et al. HCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart rates.
J. Am. Coll. Cardiol., 2013 Mar 19 , 61 (1192-201).

76

Du L et al. The role of HCN channels within the periaqueductal gray in neuropathic pain.
Brain Res., 2013 Mar 15 , 1500 (36-44).

77

Rusznák Z et al. The hyperpolarization-activated non-specific cation current (In ) adjusts the membrane properties, excitability, and activity pattern of the giant cells in the rat dorsal cochlear nucleus.
Eur. J. Neurosci., 2013 Mar , 37 (876-90).

78

Morris GM et al. Characterisation of a Right Atrial Subsidiary Pacemaker and acceleration of the pacing rate by HCN over-expression.
Cardiovasc. Res., 2013 Jun 19 , ().

79

Tibbs GR et al. HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
J. Pharmacol. Exp. Ther., 2013 Jun , 345 (363-73).

80

Cai Y et al. [Study on the effect of Klotho gene interferred by plasmid-mediated short hairpin RNA (shRNA) on sinoatrial node pacing channel gene].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2013 Jun , 30 (588-91).

81

Chowdhury S et al. Free-energy relationships in ion channels activated by voltage and ligand.
J. Gen. Physiol., 2013 Jan , 141 (11-28).

82

Cao-Ehlker X et al. Upregulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization-domain containing protein 3 (KCTD3).
J. Biol. Chem., 2013 Feb 4 , ().

83

Riesen SC et al. Myocardial expression of hyperpolarization-activated, cyclic nucleotide-gated proteins in healthy cats and cats with hypertrophic cardiomyopathy.
Schweiz. Arch. Tierheilkd., 2013 Feb , 155 (143-7).

84

Wilson CM et al. Phylogeny and effects of anoxia on hyperpolarization-activated cyclic nucleotide-gated channel gene expression in the heart of a primitive chordate, the Pacific hagfish (Eptatretus stoutii).
J. Exp. Biol., 2013 Dec 1 , 216 (4462-72).

85

Scavone A et al. Embryonic stem cell-derived CD166+ precursors develop into fully functional sinoatrial-like cells.
Circ. Res., 2013 Aug 2 , 113 (389-98).

86

Salem KA et al. Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats.
Mol. Cell. Biochem., 2013 Aug , 380 (83-96).

87

Hatch RJ et al. Peripheral hyperpolarization-activated cyclic nucleotide-gated channels contribute to inflammation-induced hypersensitivity of the rat temporomandibular joint.
Eur J Pain, 2013 Aug , 17 (972-82).

88

Evans A et al. Postmortem review and genetic analysis in sudden infant death syndrome: an 11-year review.
Hum. Pathol., 2013 Apr 25 , ().

89

Dougherty KA et al. Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus.
J. Neurophysiol., 2013 Apr , 109 (1940-53).

90

Du L et al. Inhibition of HCN channels within the periaqueductal gray attenuates neuropathic pain in rats.
Behav. Neurosci., 2013 Apr , 127 (325-9).

91

Kuwabara Y et al. Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts.
J Am Heart Assoc, 2013 , 2 (e000150).

92

Reetz O et al. Protein kinase C activation inhibits rat and human hyperpolarization activated cyclic nucleotide gated channel (HCN)1--mediated current in mammalian cells.
Cell. Physiol. Biochem., 2013 , 31 (532-41).

93

Ebadian AR et al. Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) polymorphism is associated with chronic inflammatory periodontitis. A cross-sectional study.
J Basic Clin Physiol Pharmacol, 2013 , 24 (241-4).

94

Nakamura Y et al. Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner.
PLoS ONE, 2013 , 8 (e80376).

95

Oki K et al. The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line.
Endocrinology, 2012 Sep , 153 (4328-35).

96

Yu L et al. [Endothelin-1 stimulates the expression of pacemaker channel I(f) in cardiomyocytes through a p38 MAPK-independent signaling pathway].
Nan Fang Yi Ke Da Xue Xue Bao, 2012 Sep , 32 (1274-9).

97

Gao LL et al. Expression and properties of hyperpolarization-activated current in rat dorsal root ganglion neurons with known sensory function.
J. Physiol. (Lond.), 2012 Oct 1 , 590 (4691-705).

98

Yang S et al. The distribution of HCN2-positive cells in the gastrointestinal tract of mice.
J. Anat., 2012 Oct , 221 (303-10).

99

Almanza A et al. Molecular identity, ontogeny, and cAMP modulation of the hyperpolarization-activated current in vestibular ganglion neurons.
J. Neurophysiol., 2012 Oct , 108 (2264-75).

100

Benndorf K et al. Unraveling subunit cooperativity in homotetrameric HCN2 channels.
Biophys. J., 2012 Nov 7 , 103 (1860-9).

101

Wemhöner K et al. A leucine zipper motif essential for gating of hyperpolarization-activated channels.
J. Biol. Chem., 2012 Nov 23 , 287 (40150-60).

102

Ramakrishnan NA et al. HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.
J. Biol. Chem., 2012 Nov 2 , 287 (37628-46).

103

Liao Z et al. Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: ligand-independent relief of autoinhibition in HCN4.
J. Gen. Physiol., 2012 Nov , 140 (557-66).

104

Oh YJ et al. Alterations in hyperpolarization-activated cyclic nucleotidegated cation channel (HCN) expression in the hippocampus following pilocarpine-induced status epilepticus.
BMB Rep, 2012 Nov , 45 (635-40).

105

Emery EC et al. HCN2 ion channels: an emerging role as the pacemakers of pain.
, 2012 May 19 , ().

106

Bankston JR et al. Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
, 2012 May 1 , ().

107

Del Lungo M et al. Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.
Br. J. Pharmacol., 2012 May , 166 (602-16).

108

Surges R et al. Hyperpolarization-activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy.
Biochem. Biophys. Res. Commun., 2012 Mar 30 , 420 (156-60).

109

Brager DH et al. Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome.
Cell Rep, 2012 Mar 29 , 1 (225-33).

110

Liu J et al. Angiotensin II induces protein overexpression of hyperpolarization-activated cyclic nucleotide-gated channels in primary cultured nodose neurons.
, 2012 Mar 24 , ().

111

Marcelin B et al. Dorsoventral Differences in Intrinsic Properties in Developing CA1 Pyramidal Cells.
, 2012 Mar 14 , 32 (3736-3747).

112

Suffredini S et al. Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression.
Br. J. Pharmacol., 2012 Mar , 165 (1457-66).

113

Battefeld A et al. Distinct perinatal features of the hyperpolarization-activated non-selective cation current Ih in the rat cortical plate.
, 2012 Jun 13 , 7 (21).

114

Kryukova YN et al. Ca2+-activated adenylyl cyclase 1 introduces Ca2+-dependence to beta-adrenergic stimulation of HCN2 current.
J. Mol. Cell. Cardiol., 2012 Jun , 52 (1233-9).

115

Boink GJ et al. Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2.
Circulation, 2012 Jul 31 , 126 (528-36).

116

Wu S et al. Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel.
J. Gen. Physiol., 2012 Jul , 140 (29-39).

117

Xue L et al. Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.
Urology, 2012 Jul , 80 (224.e13-8).

118

Chow SS et al. Energetics of cyclic AMP binding to HCN channel C terminus reveal negative cooperativity.
J. Biol. Chem., 2012 Jan 2 , 287 (600-6).

119

Yang J et al. Differentiation potential of human mesenchymal stem cells derived from adipose tissue and bone marrow to sinus node-like cells.
Mol Med Report, 2012 Jan , 5 (108-13).

120

Kretschmannova K et al. The expression and role of hyperpolarization-activated and cyclic nucleotide-gated channels in endocrine anterior pituitary cells.
Mol. Endocrinol., 2012 Jan , 26 (153-64).

121

Kanyshkova T et al. Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains.
Neurobiol. Dis., 2012 Jan , 45 (450-61).

122

Reid CA et al. HCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implications.
Br. J. Pharmacol., 2012 Jan , 165 (49-56).

123

Khurana S et al. An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision.
J. Neurosci., 2012 Feb 22 , 32 (2814-23).

124

Kusch J et al. How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels.
Nat. Chem. Biol., 2012 Feb , 8 (162-9).

125

Schild JH et al. Differential distribution of voltage-gated channels in myelinated and unmyelinated baroreceptor afferents.
Auton Neurosci, 2012 Dec 24 , 172 (4-12).

126

Schweikart K et al. The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity.
Toxicol In Vitro, 2012 Dec 20 , 27 (745-751).

127

Orio P et al. Role of Ih in the firing pattern of mammalian cold thermoreceptor endings.
J. Neurophysiol., 2012 Dec , 108 (3009-23).

128

Chen Y et al. Ethanol enhances human hyperpolarization-activated cyclic nucleotide-gated currents.
Alcohol. Clin. Exp. Res., 2012 Dec , 36 (2036-46).

129

Kim CS et al. Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors.
Neuron, 2012 Aug 9 , 75 (503-16).

130

Zong X et al. Regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity by cCMP.
J. Biol. Chem., 2012 Aug 3 , 287 (26506-12).

131

Angelo K et al. A biophysical signature of network affiliation and sensory processing in mitral cells.
Nature, 2012 Aug 16 , 488 (375-8).

132

Hofmann F et al. Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.
Cardiovasc. Res., 2012 Aug 1 , 95 (317-26).

133

Monticone S et al. Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells.
J. Clin. Endocrinol. Metab., 2012 Aug , 97 (E1567-72).

134

Cingolani E et al. Biological pacemaker created by percutaneous gene delivery via venous catheters in a porcine model of complete heart block.
Heart Rhythm, 2012 Aug , 9 (1310-8).

135

Oki K et al. Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis.
Endocrinology, 2012 Apr , 153 (1774-82).

136

Weng X et al. Chronic inflammatory pain is associated with increased excitability and hyperpolarization-activated current (Ih) in C- but not Aδ-nociceptors.
Pain, 2012 Apr , 153 (900-14).

137

Della Santina L et al. Processing of retinal signals in normal and HCN deficient mice.
PLoS ONE, 2012 , 7 (e29812).

138

Ying SW et al. Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.
PLoS ONE, 2012 , 7 (e42756).

139

Klueva J et al. Hyperpolarization-activated cation current contributes to spontaneous network activity in developing neocortical cultures.
Neurosignals, 2012 , 20 (35-47).

140

Acosta C et al. HCN1 and HCN2 in Rat DRG neurons: levels in nociceptors and non-nociceptors, NT3-dependence and influence of CFA-induced skin inflammation on HCN2 and NT3 expression.
PLoS ONE, 2012 , 7 (e50442).

141

Benndorf K et al. Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channels.
PLoS Comput. Biol., 2012 , 8 (e1002721).

142

Song T et al. Spironolactone diminishes spontaneous ventricular premature beats by reducing HCN4 protein expression in rats with myocardial infarction.
Mol Med Report, 2011 May-Jun , 4 (569-73).

143

Wei-qing H et al. Expression of hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN4) is increased in hypertrophic cardiomyopathy.
Cardiovasc. Pathol., 2011 Mar-Apr , 20 (110-3).

144

Emery EC et al. HCN2 ion channels play a central role in inflammatory and neuropathic pain.
Science, 2011 Sep 9 , 333 (1462-6).

145

Kraemer WP et al. Vibrational energies of LiH2(+) and LiD2(+) in the Ã1Σ+ electronic state.
J Phys Chem A, 2011 Oct 20 , 115 (11313-20).

146

Zhou Y et al. Ionic mechanisms underlying cardiac toxicity of the organochloride solvent trichloromethane.
, 2011 Oct 17 , ().

147

Poller WC et al. Lateral habenular neurons projecting to reward-processing monoaminergic nuclei express hyperpolarization-activated cyclic nucleotid-gated cation channels.
Neuroscience, 2011 Oct 13 , 193 (205-16).

148

Carrisoza-Gaytán R et al. The hyperpolarization-activated cyclic nucleotide-gated HCN2 channel transports ammonium in the distal nephron.
Kidney Int., 2011 Oct , 80 (832-40).

149

Cho HJ et al. Postnatal maturation of the hyperpolarization-activated cation current, I(h), in trigeminal sensory neurons.
J. Neurophysiol., 2011 Oct , 106 (2045-56).

150

DiFrancesco JC et al. Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy.
J. Neurosci., 2011 Nov 30 , 31 (17327-37).

151

Horwitz GC et al. HCN Channels Expressed in the Inner Ear Are Necessary for Normal Balance Function.
J. Neurosci., 2011 Nov 16 , 31 (16814-25).

152

Tu E et al. GENETIC ANALYSIS OF HYPERPOLARISATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CATION (HCN) CHANNELS IN SUDDEN UNEXPECTED DEATH IN EPILEPSY (SUDEP) CASES.
, 2011 May 25 , ().

153

Lewis AS et al. Deletion of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Auxiliary Subunit TRIP8b Impairs Hippocampal Ih Localization and Function and Promotes Antidepressant Behavior in Mice.
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