Kv7.3

1

Schütze S et al. KCNQ Potassium Channels Modulate Sensitivity of Skin D-hair Mechanoreceptors.
J. Biol. Chem., 2016 Jan 5 , ().

2

Subramani B et al. Generation and characterization of human cardiac resident and non-resident mesenchymal stem cell.
Cytotechnology, 2016 Jan 28 , ().

3

Syeda R et al. The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.
J. Biol. Chem., 2016 Feb 5 , 291 (2931-7).

4

Benned-Jensen T et al. Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.
J. Neurosci., 2016 Feb 17 , 36 (2261-6).

5

Kim KX et al. Maturation of NaV and KV Channel Topographies in the Auditory Nerve Spike Initiator before and after Developmental Onset of Hearing Function.
J. Neurosci., 2016 Feb 17 , 36 (2111-8).

6

Siloni S et al. Regulation of the neuronal KCNQ2 channel by Src--a dual rearrangement of the cytosolic termini underlies bidirectional regulation of gating.
J. Cell. Sci., 2015 Sep 15 , 128 (3489-501).

7

Provence A et al. The Novel KV7.2/KV7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility.
J. Pharmacol. Exp. Ther., 2015 Sep , 354 (290-301).

8

Jiang L et al. Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channel via CRMP-2 mediated pathway.
J. Cell. Sci., 2015 Oct 7 , ().

9

Hamada MS et al. Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability.
J. Neurosci., 2015 May 6 , 35 (7272-86).

10

Kaminsky Z et al. DNA methylation and expression of KCNQ3 in bipolar disorder.
Bipolar Disord, 2015 Mar , 17 (150-9).

11

Mills TA et al. Activation of KV7 channels stimulates vasodilatation of human placental chorionic plate arteries.
Placenta, 2015 Jun , 36 (638-44).

12

Xu M et al. An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels.
J. Biol. Chem., 2015 Jul 3 , 290 (16619-32).

13

Grinton BE et al. Familial neonatal seizures in 36 families: Clinical and genetic features correlate with outcome.
Epilepsia, 2015 Jul , 56 (1071-80).

14

Fusco C et al. A novel KCNQ3 gene mutation in a child with infantile convulsions and partial epilepsy with centrotemporal spikes.
Eur. J. Paediatr. Neurol., 2015 Jan , 19 (102-3).

15

Miceli F et al. A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability.
Epilepsia, 2015 Feb , 56 (e15-20).

16

Wang J et al. Functional analysis of potassium channels in Kv7.2 G271V mutant causing early onset familial epilepsy.
Brain Res., 2015 Aug 7 , 1616 (112-22).

17

Abidi A et al. A recurrent KCNQ2 pore mutation causing early onset epileptic encephalopathy has a moderate effect on M current but alters subcellular localization of Kv7 channels.
Neurobiol. Dis., 2015 Aug , 80 (80-92).

18

Li C et al. Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron.
Neuropharmacology, 2015 Aug , 95 (154-67).

19

Zhang F et al. Inhibition of Kv7/M Channel Currents by the Local Anesthetic Chloroprocaine.
Pharmacology, 2015 , 96 (124-30).

20

Svalø J et al. Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
PLoS ONE, 2015 , 10 (e0117350).

21

Fidzinski P et al. KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Nat Commun, 2015 , 6 (6254).

22

Allen NM et al. The variable phenotypes of KCNQ-related epilepsy.
Epilepsia, 2014 Sep , 55 (e99-105).

23

Grigorov A et al. Kv7 potassium channel subunits and M currents in cultured hippocampal interneurons.
Pflugers Arch., 2014 Sep , 466 (1747-58).

24

King CH et al. Kv7.2 regulates the function of peripheral sensory neurons.
J. Comp. Neurol., 2014 Oct 1 , 522 (3262-80).

25

Li C et al. KCNQ/Kv7 channel activator flupirtine protects against acute stress-induced impairments of spatial memory retrieval and hippocampal LTP in rats.
Neuroscience, 2014 Nov 7 , 280 (19-30).

26

Schleifenbaum J et al. Stretch-Activation of Angiotensin II Type 1a Receptors Contributes to the Myogenic Response of Mouse Mesenteric and Renal Arteries.
Circ. Res., 2014 May 16 , ().

27

Wang L et al. CAMK1 Phosphoinositide Signal-Mediated Protein Sorting and Transport Network in Human Hepatocellular Carcinoma (HCC) by Biocomputation.
Cell Biochem. Biophys., 2014 May 14 , ().

28

Mistry HD et al. Expression of voltage-dependent potassium channels in first trimester human placentae.
Placenta, 2014 May , 35 (337-40).

29

Brueggemann LI et al. KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways.
Am. J. Physiol. Lung Cell Mol. Physiol., 2014 Mar 15 , 306 (L476-86).

30

Soldovieri MV et al. Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: first evidence for an altered channel regulation by syntaxin-1A.
Hum. Mutat., 2014 Mar , 35 (356-67).

31

Orhan G et al. Dominant-negative effects of KCNQ2 mutations are associated with epileptic encephalopathy.
Ann. Neurol., 2014 Mar , 75 (382-94).

32

Liu W et al. Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons.
Mol. Cell. Neurosci., 2014 Jan , 58 (40-52).

33

Gourgy-Hacohen O et al. Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.
J. Gen. Physiol., 2014 Dec , 144 (513-27).

34

Soh H et al. Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.
J. Neurosci., 2014 Apr 9 , 34 (5311-21).

35

Maljevic S et al. Potassium channel genes and benign familial neonatal epilepsy.
Prog. Brain Res., 2014 , 213 (17-53).

36

Wu C et al. Kcnq1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish.
BMC Physiol., 2014 , 14 (1).

37

Cavaretta JP et al. Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit.
PLoS ONE, 2014 , 9 (e103655).

38

Svalø J et al. Bladder contractility is modulated by Kv7 channels in pig detrusor.
Eur. J. Pharmacol., 2013 Sep 5 , 715 (312-20).

39

Chen CP et al. An interstitial deletion of 8q23.3-q24.22 associated with Langer-Giedion syndrome, Cornelia de Lange syndrome and epilepsy.
Gene, 2013 Oct 15 , 529 (176-80).

40

Zhou P et al. Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 May 21 , 110 (8726-31).

41

Fister P et al. Benign familial neonatal convulsions caused by mutation in KCNQ3, exon 6: a European case.
Eur. J. Paediatr. Neurol., 2013 May , 17 (308-10).

42

Zara F et al. Genetic testing in benign familial epilepsies of the first year of life: clinical and diagnostic significance.
Epilepsia, 2013 Mar , 54 (425-36).

43

Boehlen A et al. The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential.
Br. J. Pharmacol., 2013 Mar , 168 (1182-200).

44

Zheng Q et al. Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model.
Pain, 2013 Mar , 154 (434-48).

45

Füll Y et al. A conserved threonine in the S1-S2 loop of KV7.2 and K V7.3 channels regulates voltage-dependent activation.
Pflugers Arch., 2013 Jun , 465 (797-804).

46

Miranda P et al. The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current.
J. Neurosci., 2013 Feb 6 , 33 (2684-96).

47

Maslarova A et al. Increased susceptibility to acetylcholine in the entorhinal cortex of pilocarpine-treated rats involves alterations in KCNQ channels.
Neurobiol. Dis., 2013 Aug , 56 (14-24).

48

Lichter-Peled A et al. Role of KCNQ2 and KCNQ3 genes in juvenile idiopathic epilepsy in Arabian foals.
Vet. J., 2013 Apr , 196 (57-63).

49

Afeli SA et al. Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle.
PLoS ONE, 2013 , 8 (e75875).

50

Robbins J et al. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
PLoS ONE, 2013 , 8 (e71809).

51

Kosenko A et al. A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity.
PLoS ONE, 2013 , 8 (e82290).

52

Ferrer T et al. Tamoxifen inhibition of kv7.2/kv7.3 channels.
PLoS ONE, 2013 , 8 (e76085).

53

Judy JT et al. Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder.
Front Genet, 2013 , 4 (87).

54

Afawi Z et al. Benign neonatal sleep myoclonus: an autosomal dominant form not allelic to KCNQ2 or KCNQ3.
J. Child Neurol., 2012 Oct , 27 (1260-3).

55

Ishii A et al. KCNQ2 abnormality in BECTS: benign childhood epilepsy with centrotemporal spikes following benign neonatal seizures resulting from a mutation of KCNQ2.
Epilepsy Res., 2012 Nov , 102 (122-5).

56

Telezhkin V et al. Structural requirements of membrane phospholipids for M-type potassium channel activation and binding.
J. Biol. Chem., 2012 Mar 23 , 287 (10001-12).

57

Hobiger K et al. Coupling of Ci-VSP modules requires a combination of structure and electrostatics within the linker.
Biophys. J., 2012 Mar 21 , 102 (1313-22).

58

Pattnaik BR et al. Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium.
Am. J. Physiol., Cell Physiol., 2012 Mar , 302 (C821-33).

59

Choveau FS et al. Pore determinants of KCNQ3 K+ current expression.
Biophys. J., 2012 Jun 6 , 102 (2489-98).

60

Choveau FS et al. Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.
Biophys. J., 2012 Jun 6 , 102 (2499-509).

61

Ebner-Bennatan S et al. Multi-faceted modulation of K+ channels by protein tyrosine phosphatase epsilon tunes neuronal excitability.
, 2012 Jun 21 , ().

62

King CH et al. Kv7.5 is the primary Kv7 subunit expressed in C-fibers.
J. Comp. Neurol., 2012 Jun 15 , 520 (1940-50).

63

Telezhkin V et al. Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2.
J. Gen. Physiol., 2012 Jul , 140 (41-53).

64

Weckhuysen S et al. KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.
Ann. Neurol., 2012 Jan , 71 (15-25).

65

Linley JE et al. M channel enhancers and physiological M channel block.
J. Physiol. (Lond.), 2012 Feb 15 , 590 (793-807).

66

Chege SW et al. Expression and function of KCNQ channels in larval zebrafish.
Dev Neurobiol, 2012 Feb , 72 (186-98).

67

Stewart AP et al. The Kv7.2/Kv7.3 heterotetramer assembles with a random subunit arrangement.
J. Biol. Chem., 2012 Apr 6 , 287 (11870-7).

68

Chadha PS et al. Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor-mediated relaxation of renal arteries in hypertension.
Hypertension, 2012 Apr , 59 (877-84).

69

Aivar P et al. Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker.
PLoS ONE, 2012 , 7 (e47263).

70

Kim JB et al. Expression patterns of two potassium channel genes in skeletal muscle cells of patients with familial hypokalemic periodic paralysis.
Neurol India, 2011 Jul-Aug , 59 (527-31).

71

Mistry HD et al. Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia.
Hypertension, 2011 Sep , 58 (497-504).

72

Etzioni A et al. Regulation of neuronal M-channel gating in an isoform-specific manner: functional interplay between calmodulin and syntaxin 1A.
J. Neurosci., 2011 Oct 5 , 31 (14158-71).

73

Klinger F et al. Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus.
Neuroimage, 2011 Oct 1 , 58 (761-9).

74

Du X et al. Characteristics and molecular basis of celecoxib modulation on Kv7 potassium channels.
, 2011 May 13 , ().

75

Zhang J et al. AKAP79/150 Signal Complexes in G-Protein Modulation of Neuronal Ion Channels.
J. Neurosci., 2011 May 11 , 31 (7199-211).

76

McCallum LA et al. The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.
J. Cell. Mol. Med., 2011 Mar , 15 (577-86).

77

Zhou X et al. Potential role of KCNQ/M-channels in regulating neuronal differentiation in mouse hippocampal and embryonic stem cell-derived neuronal cultures.
Exp. Neurol., 2011 Jun , 229 (471-83).

78

Fontán-Lozano A et al. The M-current inhibitor XE991 decreases the stimulation threshold for long-term synaptic plasticity in healthy mice and in models of cognitive disease.
Hippocampus, 2011 Jan , 21 (22-32).

79

Roepke TA et al. Fasting and 17β-estradiol differentially modulate the M-current in neuropeptide Y neurons.
J. Neurosci., 2011 Aug 17 , 31 (11825-35).

80

Cooper EC Made for "anchorin": Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons.
Semin. Cell Dev. Biol., 2011 Apr , 22 (185-92).

81

Gao Z et al. Isoform-specific Prolongation of Kv7 (KCNQ) Potassium Channel Opening Mediated by New Molecular Determinants for Drug-Channel Interactions.
J. Biol. Chem., 2010 Sep 3 , 285 (28322-32).

82

Zhong XZ et al. Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter.
J. Physiol. (Lond.), 2010 Sep 1 , 588 (3277-93).

83

Heron SE et al. Familial neonatal seizures with intellectual disability caused by a microduplication of chromosome 2q24.3.
Epilepsia, 2010 Sep , 51 (1865-9).

84

Mucha M et al. Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability.
J. Neurosci., 2010 Oct 6 , 30 (13235-45).

85

Lötsch J et al. Pharmacogenetics of new analgesics.
, 2010 Oct 13 , ().

86

Tzingounis AV et al. The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Proc. Natl. Acad. Sci. U.S.A., 2010 Jun 1 , 107 (10232-7).

87

Gómez-Posada JC et al. A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression.
J. Neurosci., 2010 Jul 7 , 30 (9316-23).

88

Serratrice G et al. [Potassium channelopathies and Morvan's syndromes].
Bull. Acad. Natl. Med., 2010 Feb , 194 (391-406; discussion 406-7).

89

Yum MS et al. The first Korean case of KCNQ2 mutation in a family with benign familial neonatal convulsions.
J. Korean Med. Sci., 2010 Feb , 25 (324-6).

90

Soh H et al. The specific slow afterhyperpolarization inhibitor UCL2077 is a subtype-selective blocker of the epilepsy associated KCNQ channels.
Mol. Pharmacol., 2010 Dec , 78 (1088-95).

91

Zhang P et al. Family-based association analysis to finemap bipolar linkage peak on chromosome 8q24 using 2,500 genotyped SNPs and 15,000 imputed SNPs.
Bipolar Disord, 2010 Dec , 12 (786-92).

92

Baulac S et al. Advances on the genetics of mendelian idiopathic epilepsies.
Clin. Lab. Med., 2010 Dec , 30 (911-29).

93

Heron SE et al. Neonatal seizures and Long QT Syndrome: A cardiocerebral channelopathy?
Epilepsia, 2009 Oct 27 , ().

94

Volkers L et al. Functional analysis of novel KCNQ2 mutations found in patients with Benign Familial Neonatal Convulsions.
Neurosci. Lett., 2009 Oct 2 , 462 (24-9).

95

Kurahashi H et al. Deletions involving both KCNQ2 and CHRNA4 present with benign familial neonatal seizures.
Neurology, 2009 Oct 13 , 73 (1214-7).

96

Padilla K et al. The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site.
Neurosci. Lett., 2009 Nov 13 , 465 (138-42).

97

Hernandez CC et al. Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels.
J. Gen. Physiol., 2009 Nov , 134 (437-48).

98

Baulac S et al. Advances on the genetics of mendelian idiopathic epilepsies.
Neurol Clin, 2009 Nov , 27 (1041-61).

99

Goldberg-Stern H et al. Novel mutation in KCNQ2 causing benign familial neonatal seizures.
Pediatr. Neurol., 2009 Nov , 41 (367-70).

100

Sugiura Y et al. Lack of potassium current in W309R mutant KCNQ3 channel causing benign familial neonatal convulsions (BFNC).
Epilepsy Res., 2009 Mar , 84 (82-5).

101

Namkung W et al. In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.
J. Biol. Chem., 2009 Jun 5 , 284 (15916-26).

102

Miceli F et al. Neutralization of a unique, negatively-charged residue in the voltage sensor of K V 7.2 subunits in a sporadic case of benign familial neonatal seizures.
Neurobiol. Dis., 2009 Jun , 34 (501-10).

103

Otto JF et al. Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions.
Epilepsia, 2009 Jul , 50 (1752-9).

104

Greenwood IA et al. KCNQ-encoded channels regulate Na+ transport across H441 lung epithelial cells.
Pflugers Arch., 2009 Feb , 457 (785-94).

105

Lange W et al. Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels.
Mol. Pharmacol., 2009 Feb , 75 (272-80).

106

de Mooij-van Malsen AJ et al. Interspecies trait genetics reveals association of Adcy8 with mouse avoidance behavior and a human mood disorder.
Biol. Psychiatry, 2009 Dec 15 , 66 (1123-30).

107

Hahn A et al. Sodium and potassium channel dysfunctions in rare and common idiopathic epilepsy syndromes.
Brain Dev., 2009 Aug , 31 (515-20).

108

Brown DA et al. Neural KCNQ (Kv7) channels.
Br. J. Pharmacol., 2009 Apr , 156 (1185-95).

109

Regev N et al. Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity.
PLoS ONE, 2009 , 4 (e6586).

110

Jin Z et al. Expression and localization of K channels KCNQ2 and KCNQ3 in the mammalian cochlea.
Audiol. Neurootol., 2009 , 14 (98-105).

111

Wickenden AD et al. Kv7 channels as targets for the treatment of pain.
Curr. Pharm. Des., 2009 , 15 (1773-98).

112

Roura-Ferrer M et al. Functional implications of KCNE subunit expression for the Kv7.5 (KCNQ5) channel.
Cell. Physiol. Biochem., 2009 , 24 (325-34).

113

Roeloffs R et al. In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models.
J. Pharmacol. Exp. Ther., 2008 Sep , 326 (818-28).

114

Hernandez CC et al. A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.
J. Gen. Physiol., 2008 Sep , 132 (361-81).

115

Bal M et al. Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.
J. Biol. Chem., 2008 Nov 7 , 283 (30668-76).

116

Nyholt DR et al. A high-density association screen of 155 ion transport genes for involvement with common migraine.
Hum. Mol. Genet., 2008 Nov 1 , 17 (3318-31).

117

Bal M et al. Calmodulin binding to M-type K+ channels assayed by TIRF/FRET in living cells.
J. Physiol. (Lond.), 2008 May 1 , 586 (2307-20).

118

Kanaumi T et al. Developmental changes in KCNQ2 and KCNQ3 expression in human brain: possible contribution to the age-dependent etiology of benign familial neonatal convulsions.
Brain Dev., 2008 May , 30 (362-9).

119

Liu B et al. Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons.
Neuropharmacology, 2008 Mar , 54 (629-39).

120

Wickenden AD et al. N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator.
Mol. Pharmacol., 2008 Mar , 73 (977-86).

121

Li H et al. A novel mutation of KCNQ3 gene in a Chinese family with benign familial neonatal convulsions.
Epilepsy Res., 2008 Mar , 79 (1-5).

122

Uehara A et al. Altered KCNQ3 potassium channel function caused by the W309R pore-helix mutation found in human epilepsy.
J. Membr. Biol., 2008 Mar , 222 (55-63).

123

Shah MM et al. Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons.
Proc. Natl. Acad. Sci. U.S.A., 2008 Jun 3 , 105 (7869-74).

124

Nakajo K et al. Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks.
J. Physiol. (Lond.), 2008 Jun 15 , 586 (2827-40).

125

Neubauer BA et al. KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes.
Neurology, 2008 Jul 15 , 71 (177-83).

126

Singh NA et al. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization.
J. Physiol. (Lond.), 2008 Jul 15 , 586 (3405-23).

127

Schuetz F et al. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.
Am. J. Physiol., Cell Physiol., 2008 Jul , 295 (C73-80).

128

Fedorenko O et al. A schizophrenia-linked mutation in PIP5K2A fails to activate neuronal M channels.
Psychopharmacology (Berl.), 2008 Jul , 199 (47-54).

129

Wuttke TV et al. Neutralization of a negative charge in the S1-S2 region of the KV7.2 (KCNQ2) channel affects voltage-dependent activation in neonatal epilepsy.
J. Physiol. (Lond.), 2008 Jan 15 , 586 (545-55).

130

Xiong Q et al. Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.
Proc. Natl. Acad. Sci. U.S.A., 2008 Feb 26 , 105 (3128-33).

131

Wladyka CL et al. The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats.
J. Physiol. (Lond.), 2008 Feb 1 , 586 (795-802).

132

Moser SL et al. Multiple KCNQ potassium channel subtypes mediate basal anion secretion from the human airway epithelial cell line Calu-3.
J. Membr. Biol., 2008 Feb , 221 (153-63).

133

Miceli F et al. Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs.
, 2008 Feb , 8 (65-74).

134

Tzingounis AV et al. Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents.
Proc. Natl. Acad. Sci. U.S.A., 2008 Dec 16 , 105 (19974-9).

135

Zaika O et al. Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.
Biophys. J., 2008 Dec , 95 (5121-37).

136

Hernandez CC et al. Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1811-21).

137

Maljevic S et al. Nervous system KV7 disorders: breakdown of a subthreshold brake.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1791-801).

138

Hansen HH et al. Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1823-32).

139

Sadewa AH et al. Germ-line mutation of KCNQ2, p.R213W, in a Japanese family with benign familial neonatal convulsion.
Pediatr Int, 2008 Apr , 50 (167-71).

140

Yalçin O et al. A novel missense mutation (N258S) in the KCNQ2 gene in a Turkish family afflicted with benign familial neonatal convulsions (BFNC).
Turk. J. Pediatr., 2007 Oct-Dec , 49 (385-9).

141

Soldovieri MV et al. Correlating the clinical and genetic features of benign familial neonatal seizures (BFNS) with the functional consequences of underlying mutations.
Channels (Austin), 2007 Jul-Aug , 1 (228-33).

142

Lucarini N et al. Genetic polymorphisms and idiopathic generalized epilepsies.
Pediatr. Neurol., 2007 Sep , 37 (157-64).

143

Roepke TA et al. Estrogen regulation of genes important for K+ channel signaling in the arcuate nucleus.
Endocrinology, 2007 Oct , 148 (4937-51).

144

Bai X et al. Electrophysiological properties of human adipose tissue-derived stem cells.
Am. J. Physiol., Cell Physiol., 2007 Nov , 293 (C1539-50).

145

Qiu C et al. K+ M-current regulates the transition to seizures in immature and adult hippocampus.
Epilepsia, 2007 Nov , 48 (2047-58).

146

Soldovieri MV et al. Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions.
J. Neurosci., 2007 May 2 , 27 (4919-28).

147

Xiong Q et al. Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants.
Nat. Chem. Biol., 2007 May , 3 (287-96).

148

Rasmussen HB et al. Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.
J. Cell. Sci., 2007 Mar 15 , 120 (953-63).

149

Martire M et al. Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes.
J. Neurochem., 2007 Jul , 102 (179-93).

150

Heron SE et al. Deletions or duplications in KCNQ2 can cause benign familial neonatal seizures.
J. Med. Genet., 2007 Dec , 44 (791-6).

151

Brown DA et al. Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition.
J. Physiol. (Lond.), 2007 Aug 1 , 582 (917-25).

152

Ekberg J et al. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2.
J. Biol. Chem., 2007 Apr 20 , 282 (12135-42).

153

Jensen HS et al. Inactivation as a new regulatory mechanism for neuronal Kv7 channels.
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