Cavα2δ3

Description: calcium channel, voltage-dependent, alpha2/delta subunit 3
Gene: Cacna2d3
Alias: cacna2d3

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	55799	3	952005
Mouse	12294	14	817832
Rat	306243	16	814059

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_018398.3	3789
Mouse	NM_009785.1	3710
Rat	NM_175595.2	3276

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	Q8IZS8	1091
Mouse	Q9Z1L5	1091
Rat	Q8CFG5	1085

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NM_009785.1

3710

NP_033915.1

1091

Predicted

XR_001781093.3

3313

transcript variant X5

XM_036158421.1

4498

XP_036014314.1

1055

transcript variant X3

isoform X3

XM_011244938.4

4516

XP_011243240.1

1061

transcript variant X2

isoform X2

XM_006518486.5

4588

XP_006518549.1

1085

transcript variant X1

isoform X1

XM_030247616.2

3587

XP_030103476.1

997

transcript variant X4

isoform X4

Known

NM_175595.2

3276

NP_783185.1

1085

Predicted

XR_005494605.1

3739

transcript variant X2

XR_005494606.1

2137

transcript variant X4

XM_017600077.2

3596

XP_017455566.2

1091

transcript variant X1

isoform X1

XM_039094442.1

3262

XP_038950370.1

997

transcript variant X3

isoform X2

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Post-Translational Modifications

PTM

Position

Type

Modified residue

924

Phosphotyrosine

Glycosylation

166

N-linked (GlcNAc...) asparagine

Glycosylation

309

N-linked (GlcNAc...) asparagine

Glycosylation

553

N-linked (GlcNAc...) asparagine

Glycosylation

632

N-linked (GlcNAc...) asparagine

Glycosylation

793

N-linked (GlcNAc...) asparagine

Disulfide bond

643

Interchain (between alpha-2-3 and delta-3 chains)

Modified residue

924

Phosphotyrosine

Glycosylation

166

N-linked (GlcNAc...) asparagine

Glycosylation

309

N-linked (GlcNAc...) asparagine

Glycosylation

553

N-linked (GlcNAc...) asparagine

Glycosylation

632

N-linked (GlcNAc...) asparagine

Disulfide bond

643

Interchain (between alpha-2-3 and delta-3 chains)

Modified residue

918

Phosphotyrosine

Glycosylation

166

N-linked (GlcNAc...) asparagine

Glycosylation

309

N-linked (GlcNAc...) asparagine

Glycosylation

547

N-linked (GlcNAc...) asparagine

Glycosylation

626

N-linked (GlcNAc...) asparagine

Disulfide bond

637

Interchain (between alpha-2-3 and delta-3 chains)

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Structure

Cavα2δ3 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	6201.51	source
Mouse	6185.96	source
Rat	7062.27	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/102/ , accessed on 2024 Nov 21

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