TRPV1

Description: transient receptor potential cation channel, subfamily V, member 1
Gene: Trpv1
Alias: TRPV1

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Gene

Species	NCBI gene ID	Chromosome	Position
Human	7442	17	43965
Mouse	193034	11	27173
Rat	83810	10	25085

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Transcript

Species	NCBI accession	Length (nt)
Human	NM_080704.4	4164
Mouse	NM_001001445.2	3587
Rat	NM_031982.1	2847

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Protein Isoforms

Species	Uniprot ID	Length (aa)
Human	Q8NER1	839
Mouse	Q704Y3	839
Rat	O35433	838

Isoforms

Transcript

Length (nt)

Protein

Length (aa)

Variant

Isoform

Known

NM_080704.4

4164

NP_542435.2

839

transcript variant 1

NM_018727.5

4074

NP_061197.4

839

transcript variant 2

NM_080705.4

4090

NP_542436.2

839

transcript variant 4

NM_080706.3

4443

NP_542437.2

839

transcript variant 3

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Post-Translational Modifications

PTM

Position

Type

Modified residue

117

Phosphoserine; by PKA and PKD

Modified residue

145

Phosphothreonine; by PKA; in vitro

Modified residue

371

Phosphothreonine; by PKA; in vitro

Modified residue

502

Phosphoserine; by PKC/PRKCE

Modified residue

705

Phosphothreonine

Modified residue

775

Phosphoserine

Modified residue

801

Phosphoserine; by PKC/PRKCE and PKC/PRKCZ

Modified residue

821

Phosphoserine

Glycosylation

604

N-linked (GlcNAc...) asparagine

Modified residue

117

Phosphoserine; by PKA and PKD

Modified residue

145

Phosphothreonine; by PKA; in vitro

Modified residue

371

Phosphothreonine; by PKA; in vitro

Modified residue

503

Phosphoserine; by PKC/PRKCE

Modified residue

705

Phosphothreonine

Modified residue

775

Phosphoserine

Modified residue

801

Phosphoserine; by PKC/PRKCE and PKC/PRKCZ

Modified residue

821

Phosphoserine

Glycosylation

605

N-linked (GlcNAc...) asparagine

Modified residue

116

Phosphoserine; by PKA and PKD

Modified residue

144

Phosphothreonine; by PKA; in vitro

Modified residue

370

Phosphothreonine; by PKA; in vitro

Modified residue

502

Phosphoserine; by PKC/PRKCE

Modified residue

704

Phosphothreonine

Modified residue

774

Phosphoserine; by PKA; in vitro

Modified residue

800

Phosphoserine; by PKC/PRKCE and PKC/PRKCZ

Modified residue

820

Phosphoserine; by PKA; in vitro

Glycosylation

604

N-linked (GlcNAc...) asparagine

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Structure

TRPV1 predicted AlphaFold size

Species	Area (Å²)	Reference
Human	5191.73	source
Mouse	5486.92	source
Rat	5380.01	source

Methodology for AlphaFold size prediction and disclaimer are available here

References

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Credits

To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/wikipages/173/ , accessed on 2024 Nov 21

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