Channelpedia

TRPA1

675 literature references associated to TRPA1

used / unused
Pubmed id

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364803

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365004

McEntire DM et al. Pain transduction: a pharmacologic perspective.
Expert Rev Clin Pharmacol, 2016 May 23 , (1-12).

4

364919

Babes A et al. Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.
J. Neurosci., 2016 May 11 , 36 (5264-78).

10

368073

Meents JE et al. Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.
J. Physiol. (Lond.), 2016 Jun 16 , ().

12

361545

13

361689

Verma VA et al. α-Aryl pyrrolidine sulfonamides as TRPA1 antagonists.
Bioorg. Med. Chem. Lett., 2016 Jan 15 , 26 (495-8).

15

361859

16

365625

Snyder LM et al. An Unexpected Role for TRPV4 in Serotonin-Mediated Itch.
J. Invest. Dermatol., 2016 Jan , 136 (7-9).

17

365647

21

365803

Brozmanova M et al. Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers.
Am. J. Physiol. Gastrointest. Liver Physiol., 2016 Feb 1 , 310 (G215-23).

22

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23

365690

26

365030

Devos FC et al. Neuro-immune interactions in chemical-induced airway hyperreactivity.
Eur. Respir. J., 2016 Apr 28 , ().

28

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Jian T et al. TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch.
Neural Plast., 2016 , 2016 (1682972).

32

364872

Wu X et al. Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE, 2016 , 11 (e0155577).

33

365248

da Silva Serra I et al. Characterization of cutaneous and articular sensory neurons.
Mol Pain, 2016 , 12 ().

35

364807

Laursen WJ et al. Species-specific temperature sensitivity of TRPA1.
Temperature (Austin), 2015 Apr-Jun , 2 (214-26).

38

366781

Pradhananga S et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.
Eur. J. Pharmacol., 2015 Sep 5 , 762 (313-21).

40

356761

Paulsen CE et al. Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 2015 Sep 24 , 525 (552).

42

356292

43

356344

Dai Y TRPs and pain.
Semin Immunopathol, 2015 Sep 15 , ().

44

357153

Billeter AT et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Surgery, 2015 Sep , 158 (646-54).

45

367839

Nishimoto R et al. Propofol-induced pain sensation involves multiple mechanisms in sensory neurons.
Pflugers Arch., 2015 Sep , 467 (2011-20).

46

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50

366084

Oda M et al. Chemical sensing properties of Takifugu TRPA1.
Neuroreport, 2015 Oct 21 , 26 (908-14).

51

365916

Kichko TI et al. Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Oct 15 , 309 (L812-20).

52

356122

Yu X et al. TRP channel functions in the gastrointestinal tract.
Semin Immunopathol, 2015 Oct 12 , ().

53

356141

Patel R et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci., 2015 Oct 10 , ().

55

368242

Barbagallo B et al. Temperature sensation in Drosophila.
Curr. Opin. Neurobiol., 2015 Oct , 34 (8-13).

56

362843

58

365957

Okada Y et al. Transient Receptor Potential Channels and Corneal Stromal Inflammation.
Cornea, 2015 Nov , 34 Suppl 11 (S136-41).

59

366076

El Karim I et al. TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells.
Am. J. Pathol., 2015 Nov , 185 (2994-3002).

60

357601

Mollanazar NK et al. Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?
Clin Rev Allergy Immunol, 2015 May 1 , ().

64

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Gualdani R et al. Lipoic-based TRPA1/TRPV1 antagonist to treat orofacial pain.
ACS Chem Neurosci, 2015 Mar 18 , 6 (380-5).

65

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67

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Liu Z et al. Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Mar 15 , 308 (G482-8).

69

363498

Del Prete D et al. Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands.
Bioorg. Med. Chem. Lett., 2015 Mar 1 , 25 (1009-11).

71

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Peng G et al. Evolution of TRP channels inferred by their classification in diverse animal species.
Mol. Phylogenet. Evol., 2015 Mar , 84 (145-57).

72

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73

358414

Urata K et al. Involvement of TRPV1 and TRPA1 in incisional intraoral and extraoral pain.
J. Dent. Res., 2015 Mar , 94 (446-54).

75

357693

Andersson DA et al. Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.
J. Biol. Chem., 2015 Jun 12 , 290 (15185-96).

76

367562

Benemei S et al. TRP channels.
Curr Opin Pharmacol, 2015 Jun , 22 (18-23).

77

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79

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Peng G et al. Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1.
Cell Rep, 2015 Jul 14 , 12 (190-202).

80

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Meng Q et al. Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers.
Am. J. Physiol., Cell Physiol., 2015 Jul 1 , 309 (C1-10).

81

357084

Morita T et al. HTR7 Mediates Serotonergic Acute and Chronic Itch.
Neuron, 2015 Jul 1 , 87 (124-38).

85

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Sherkheli MA et al. Borneol inhibits TRPA1, a proinflammatory and noxious pain-sensing cation channel.
Pak J Pharm Sci, 2015 Jul , 28 (1357-63).

86

367500

Nassini R et al. The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Br. J. Pharmacol., 2015 Jul , 172 (3397-411).

89

348902

Palkar R et al. The molecular and cellular basis of thermosensation in mammals.
Curr. Opin. Neurobiol., 2015 Jan 23 , 34C (14-19).

90

363872

Pinheiro Fde V et al. The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain.
Eur. J. Pharmacol., 2015 Jan 15 , 747 (105-13).

92

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Canner JP et al. Developmental regulation of trigeminal TRPA1 by the cornea.
Invest. Ophthalmol. Vis. Sci., 2015 Jan , 56 (29-36).

93

359011

97

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Yrbas ML et al. Pharmacological mechanism underlying the antinociceptive activity of vanillic acid.
Pharmacol. Biochem. Behav., 2015 Feb 21 , 132 (88-95).

98

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Weyer AD et al. Loosening Pain's Grip by Tightening TRPV1-TRPA1 Interactions.
Neuron, 2015 Feb 18 , 85 (661-3).

99

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100

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107

365946

Pires PW et al. Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.
Am. J. Physiol. Heart Circ. Physiol., 2015 Dec 15 , 309 (H2031-41).

108

366843

Deering-Rice CE et al. Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma.
Am. J. Respir. Cell Mol. Biol., 2015 Dec , 53 (893-901).

112

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115

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116

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117

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Carpi S et al. AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells.
Anticancer Drugs, 2015 Aug , 26 (754-62).

118

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Paulsen CE et al. Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 2015 Apr 8 , ().

120

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Clapham DE Structural biology: Pain-sensing TRPA1 channel resolved.
Nature, 2015 Apr 23 , 520 (439-41).

122

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Katagiri A et al. Evidence for TRPA1 involvement in central neural mechanisms in a rat model of dry eye.
Neuroscience, 2015 Apr 2 , 290 (204-13).

124

358281

Kubota K et al. Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Apr 1 , 308 (G579-90).

128

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Chen J et al. TRPA1 as a drug target--promise and challenges.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Apr , 388 (451-63).

129

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131

361937

Watanabe T et al. Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods.
J. Nutr. Sci. Vitaminol., 2015 , 61 Suppl (S86-8).

132

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133

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Fischer MJ et al. Formalin evokes calcium transients from the endoplasmatic reticulum.
PLoS ONE, 2015 , 10 (e0123762).

136

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138

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142

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144

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145

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Kozai D et al. Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels.
Curr Neuropharmacol, 2015 , 13 (266-78).

146

357347

Belmonte C et al. What Causes Eye Pain?
Curr Ophthalmol Rep, 2015 , 3 (111-121).

147

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Lötsch J et al. Multimodal distribution of human cold pain thresholds.
PLoS ONE, 2015 , 10 (e0125822).

149

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Moon H et al. Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa.
PLoS ONE, 2015 , 10 (e0127060).

154

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Preti D et al. Transient receptor potential ankyrin 1 (TRPA1) antagonists.
Pharm Pat Anal, 2015 , 4 (75-94).

156

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Mueller-Tribbensee SM et al. Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice.
PLoS ONE, 2015 , 10 (e0128242).

157

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160

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Sadaf S et al. Serotonergic neurons of the Drosophila air-puff-stimulated flight circuit.
J. Biosci., 2014 Sep , 39 (575-83).

165

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Egbuniwe O et al. TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.
J. Dent. Res., 2014 Sep , 93 (911-7).

166

350978

Greaves E et al. Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis.
J. Clin. Endocrinol. Metab., 2014 Sep , 99 (E1738-43).

168

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Avenali L et al. Annexin A2 regulates TRPA1-dependent nociception.
J. Neurosci., 2014 Oct 29 , 34 (14506-16).

170

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Pazienza V et al. The TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling.
Am. J. Physiol. Heart Circ. Physiol., 2014 Oct 1 , 307 (H939-44).

171

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174

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Saarnilehto M et al. Contact sensitizer 2,4-dinitrochlorobenzene is a highly potent human TRPA1 agonist.
Allergy, 2014 Oct , 69 (1424-7).

175

350729

Deering-Rice CE et al. Drofenine: A 2-APB Analogue with Greater Selectivity for Human TRPV3.
Pharmacol Res Perspect, 2014 Oct , 2 (e00062).

176

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Shimizu S et al. Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Eur. J. Pharmacol., 2014 Nov 5 , 742 (22-30).

177

349600

Moparthi L et al. Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain.
Proc. Natl. Acad. Sci. U.S.A., 2014 Nov 25 , 111 (16901-6).

180

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Oguri G et al. Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.
Am. J. Physiol. Heart Circ. Physiol., 2014 Nov 1 , 307 (H1339-52).

183

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186

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Cheah EY et al. Acrolein relaxes mouse isolated tracheal smooth muscle via a TRPA1-dependent mechanism.
Biochem. Pharmacol., 2014 May 1 , 89 (148-56).

187

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188

344611

Franken J et al. TRP channels in lower urinary tract dysfunction.
Br. J. Pharmacol., 2014 May , 171 (2537-51).

189

353612

Nakajima S et al. Unsaturated aldehydes induce CCK secretion via TRPA1 in STC-1 cells.
Mol Nutr Food Res, 2014 May , 58 (1042-51).

190

354209

Benemei S et al. The TRPA1 channel in migraine mechanism and treatment.
Br. J. Pharmacol., 2014 May , 171 (2552-67).

191

354504

Kaneko Y et al. Transient receptor potential (TRP) channels: a clinical perspective.
Br. J. Pharmacol., 2014 May , 171 (2474-507).

192

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Gautier M et al. New insights into pharmacological tools to TR(i)P cancer up.
Br. J. Pharmacol., 2014 May , 171 (2582-92).

193

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Chung G et al. Activation of transient receptor potential ankyrin 1 by eugenol.
Neuroscience, 2014 Mar 7 , 261 (153-60).

195

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197

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199

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Tran VT et al. Mechanotransduction channels of the trabecular meshwork.
Curr. Eye Res., 2014 Mar , 39 (291-303).

200

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203

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Copeland KW et al. Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
Bioorg. Med. Chem. Lett., 2014 Jun 6 , ().

205

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Huynh KW et al. Application of Amphipols for Structure-Functional Analysis of TRP Channels.
J. Membr. Biol., 2014 Jun 4 , ().

206

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208

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Bennett DL et al. Painful and painless channelopathies.
Lancet Neurol, 2014 Jun , 13 (587-99).

210

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213

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Laliberté S et al. Discovery of a series of aryl-N-(3-(alkylamino)-5-(trifluoromethyl)phenyl)benzamides as TRPA1 antagonists.
Bioorg. Med. Chem. Lett., 2014 Jul 15 , 24 (3204-6).

214

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216

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Deberry JJ et al. TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis.
Pain, 2014 Jul , 155 (1280-7).

217

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Trevisan G et al. Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
Naunyn Schmiedebergs Arch. Pharmacol., 2014 Jul , 387 (679-89).

219

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221

341471

Kurganov E et al. Heat and AITC activate green anole TRPA1 in a membrane-delimited manner.
Pflugers Arch., 2014 Jan 3 , ().

222

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Teichert RW et al. Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jan 27 , ().

223

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224

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225

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226

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Gohlke BO et al. SuperPain--a resource on pain-relieving compounds targeting ion channels.
Nucleic Acids Res., 2014 Jan 1 , 42 (D1107-12).

227

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Kozai D et al. Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators.
Mol. Pharmacol., 2014 Jan , 85 (175-85).

228

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229

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231

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Brenneis C et al. Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.
Br. J. Pharmacol., 2014 Jan , 171 (438-51).

232

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234

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237

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Bellono NW et al. UV light activates a Gαq/11-coupled phototransduction pathway in human melanocytes.
J. Gen. Physiol., 2014 Feb , 143 (203-14).

238

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239

350023

Barabas ME et al. Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice.
J. Biol. Chem., 2014 Dec 5 , 289 (34241-9).

240

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Amato A et al. Involvement of cholinergic nicotinic receptors in the menthol-induced gastric relaxation.
Eur. J. Pharmacol., 2014 Dec 15 , 745 (129-34).

242

358858

Ortar G et al. Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
Bioorg. Med. Chem. Lett., 2014 Dec 1 , 24 (5507-11).

244

350309

Lieu T et al. The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Gastroenterology, 2014 Dec , 147 (1417-28).

246

364071

Honda K et al. TRPA1 contributes to capsaicin-induced facial cold hyperalgesia in rats.
Eur. J. Oral Sci., 2014 Dec , 122 (391-6).

247

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Rofes L et al. Effect of oral piperine on the swallow response of patients with oropharyngeal dysphagia.
J. Gastroenterol., 2014 Dec , 49 (1517-23).

248

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Fischer MJ et al. Direct evidence for functional TRPV1/TRPA1 heteromers.
Pflugers Arch., 2014 Dec , 466 (2229-41).

250

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251

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Kozai D et al. Redox regulation of transient receptor potential channels.
Antioxid. Redox Signal., 2014 Aug 20 , 21 (971-86).

252

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253

351301

Suzuki H et al. The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.
Am. J. Physiol., Cell Physiol., 2014 Aug 15 , 307 (C384-94).

255

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257

344894

Themistocleous AC et al. The clinical approach to small fibre neuropathy and painful channelopathy.
Pract Neurol, 2014 Apr 28 , ().

258

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259

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Sato A et al. Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori.
Proc. Natl. Acad. Sci. U.S.A., 2014 Apr 1 , 111 (E1249-55).

261

354085

Pokorski M et al. The hypoxic ventilatory response and TRPA1 antagonism in conscious mice.
Acta Physiol (Oxf), 2014 Apr , 210 (928-38).

262

353215

Geppetti P et al. Transient receptor potential channels and occupational exposure.
Curr Opin Allergy Clin Immunol, 2014 Apr , 14 (77-83).

272

351975

Zygmunt PM et al. TRPA1.
Handb Exp Pharmacol, 2014 , 222 (583-630).

274

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275

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Shimizu S et al. TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters).
Handb Exp Pharmacol, 2014 , 223 (767-94).

276

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Hardie RC Photosensitive TRPs.
Handb Exp Pharmacol, 2014 , 223 (795-826).

277

351256

Roper SD TRPs in taste and chemesthesis.
Handb Exp Pharmacol, 2014 , 223 (827-71).

279

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Laursen WJ et al. TRPA1 channels: chemical and temperature sensitivity.
Curr Top Membr, 2014 , 74 (89-112).

280

349687

Cohen MR et al. Structure of thermally activated TRP channels.
Curr Top Membr, 2014 , 74 (181-211).

282

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Baez D et al. Gating of thermally activated channels.
Curr Top Membr, 2014 , 74 (51-87).

284

344710

Steinberg X et al. A structural view of ligand-dependent activation in thermoTRP channels.
Front Physiol, 2014 , 5 (171).

287

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288

359368

293

364569

Bell JT et al. Differential methylation of the TRPA1 promoter in pain sensitivity.
Nat Commun, 2014 , 5 (2978).

296

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Minett MS et al. Significant determinants of mouse pain behaviour.
PLoS ONE, 2014 , 9 (e104458).

299

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300

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302

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303

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Nassini R et al. The TRPA1 channel in inflammatory and neuropathic pain and migraine.
Rev. Physiol. Biochem. Pharmacol., 2014 , 167 (1-43).

305

353932

Malmquist J et al. Imaging agent of a TRPA1 inhibitor.
J Labelled Comp Radiopharm, 2013 Jul-Aug , 56 (536-7).

306

347234

Lucaciu OC et al. Itch sensation through transient receptor potential channels: a systematic review and relevance to manual therapy.
J Manipulative Physiol Ther, 2013 Jul-Aug , 36 (385-93).

309

339898

Kamakura T et al. Functional expression of TRPV1 and TRPA1 in rat vestibular ganglia.
Neurosci. Lett., 2013 Sep 27 , 552C (92-97).

310

339534

Chen J et al. Species differences and molecular determinant of TRPA1 cold sensitivity.
Nat Commun, 2013 Sep 27 , 4 (2501).

312

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Koivisto A et al. TRPA1: A Transducer and Amplifier of Pain and Inflammation.
Basic Clin. Pharmacol. Toxicol., 2013 Sep 17 , ().

314

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Brederson JD et al. Targeting TRP channels for pain relief.
Eur. J. Pharmacol., 2013 Sep 15 , 716 (61-76).

316

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317

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321

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Julius D TRP Channels and Pain.
Annu. Rev. Cell Dev. Biol., 2013 Oct 6 , 29 (355-384).

322

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Ortar G et al. 3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.
Bioorg. Med. Chem. Lett., 2013 Oct 15 , 23 (5614-8).

323

342144

324

342588

Hsu CC et al. Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2013 Oct 1 , 305 (R769-79).

329

341876

Zhang XY et al. Gain-of-function mutations in SCN11A cause familial episodic pain.
Am. J. Hum. Genet., 2013 Nov 7 , 93 (957-66).

330

341716

Grace MS et al. Transient Receptor Potential (TRP) channels in the airway: role in airway disease.
Br. J. Pharmacol., 2013 Nov 28 , ().

331

341714

Sisignano M et al. TRP-channels as key integrators of lipid pathways in nociceptive neurons.
Prog. Lipid Res., 2013 Nov 25 , 53C (93-107).

334

354450

Krimon S et al. P2X3 receptors induced inflammatory nociception modulated by TRPA1, 5-HT3 and 5-HT1A receptors.
Pharmacol. Biochem. Behav., 2013 Nov , 112 (49-55).

336

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337

347752

Hoffmann T et al. TRPA1 and TRPV1 are differentially involved in heat nociception of mice.
Eur J Pain, 2013 Nov , 17 (1472-82).

341

335217

Wilson SR et al. The ion channel TRPA1 is required for chronic itch.
J. Neurosci., 2013 May 29 , 33 (9283-94).

343

335668

Rios ER et al. TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
Chem. Biol. Interact., 2013 May 25 , 203 (573-9).

344

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346

336010

348

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350

340477

Ibarra Y et al. Benzoquinone reveals a cysteine-dependent desensitization mechanism of TRPA1.
Mol. Pharmacol., 2013 May , 83 (1120-32).

356

336654

Li C et al. Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis.
Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Mar 1 , 304 (G490-500).

358

340419

Perin-Martins A et al. Mechanisms underlying transient receptor potential ankyrin 1 (TRPA1)-mediated hyperalgesia and edema.
J. Peripher. Nerv. Syst., 2013 Mar , 18 (62-74).

360

335036

Verkhratsky A et al. TRP Channels Coordinate Ion Signalling in Astroglia.
Rev. Physiol. Biochem. Pharmacol., 2013 Jun 20 , ().

361

335089

Bellono NW et al. UV light phototransduction depolarizes human melanocytes.
Channels (Austin), 2013 Jun 13 , 7 ().

363

335109

Gees M et al. Mechanisms of TRPV1 Activation and Sensitization by Allyl Isothiocyanate.
Mol. Pharmacol., 2013 Jun 11 , ().

364

340337

Cattaruzza F et al. Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Jun 1 , 304 (G1002-12).

365

343811

Tong X et al. Genetically encoded calcium indicators and astrocyte calcium microdomains.
Neuroscientist, 2013 Jun , 19 (274-91).

367

343582

Szolcsányi J et al. Transient receptor potential vanilloid 1 as a therapeutic target in analgesia.
Expert Opin. Ther. Targets, 2013 Jun , 17 (641-57).

368

340610

Kimura Y et al. Polysulfides are possible H2S-derived signaling molecules in rat brain.
FASEB J., 2013 Jun , 27 (2451-7).

369

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Park S et al. Cold exposure lowers energy expenditure at the cellular level.
Cell Biol. Int., 2013 Jun , 37 (638-42).

371

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374

335676

375

337579

377

336593

Tang X et al. Temperature integration at the AC thermosensory neurons in Drosophila.
J. Neurosci., 2013 Jan 16 , 33 (894-901).

379

331042

380

330947

Farco JA et al. Menthol - pharmacology of an important naturally medicinal "cool".
Mini Rev Med Chem, 2013 Jan 1 , 13 (124-31).

381

330592

Wong BW et al. Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes.
Trends Biochem. Sci., 2013 Jan , 38 (3-11).

384

337441

De Petrocellis L et al. 2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation.
Expert Opin Ther Pat, 2013 Jan , 23 (119-47).

385

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Bellono NW et al. UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes.
Proc. Natl. Acad. Sci. U.S.A., 2013 Feb 5 , 110 (2383-8).

386

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387

336152

388

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Kono T et al. Epithelial transient receptor potential ankyrin 1 (TRPA1)-dependent adrenomedullin upregulates blood flow in rat small intestine.
Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Feb 15 , 304 (G428-36).

391

337040

Schulze A et al. Apomorphine is a bimodal modulator of TRPA1 channels.
Mol. Pharmacol., 2013 Feb , 83 (542-51).

392

336407

Nakagawa T et al. [Roles of TRPA1 in acute peripheral neuropathy characteristically induced by oxaliplatin].
Nippon Yakurigaku Zasshi, 2013 Feb , 141 (76-80).

397

331271

Smith PK et al. Transient Receptor Potentials (TRPs) and Anaphylaxis.
Curr Allergy Asthma Rep, 2013 Feb , 13 (93-100).

399

346501

Oh MH et al. TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
J. Immunol., 2013 Dec 1 , 191 (5371-82).

400

334821

Bassoli A et al. Analogues of perillaketone as highly potent agonists of TRPA1 channel.
Food Chem, 2013 Dec 1 , 141 (2044-51).

401

346809

Wang S et al. Etodolac activates and desensitizes transient receptor potential ankyrin 1.
J. Neurosci. Res., 2013 Dec , 91 (1591-8).

405

339886

406

339878

407

339719

408

339790

Alpizar YA et al. Allyl isothiocyanate sensitizes TRPV1 to heat stimulation.
Pflugers Arch., 2013 Aug 18 , ().

409

339782

410

347191

411

348182

413

343693

414

335755

Matsushita A et al. Inhibition by TRPA1 agonists of compound action potentials in the frog sciatic nerve.
Biochem. Biophys. Res. Commun., 2013 Apr 26 , 434 (179-84).

416

335518

Nilius B et al. Spices: The Savory and Beneficial Science of Pungency.
Rev. Physiol. Biochem. Pharmacol., 2013 Apr 19 , ().

417

335256

418

335551

421

336374

Kokel D et al. Photochemical activation of TRPA1 channels in neurons and animals.
Nat. Chem. Biol., 2013 Apr , 9 (257-63).

422

340801

Fariss MW et al. Emerging mechanistic targets in lung injury induced by combustion-generated particles.
Toxicol. Sci., 2013 Apr , 132 (253-67).

423

346437

Andersson DA et al. Methylglyoxal evokes pain by stimulating TRPA1.
PLoS ONE, 2013 , 8 (e77986).

424

342725

Nativi C et al. A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain.
Sci Rep, 2013 , 3 (2005).

425

341159

Bautista DM et al. TRPA1: A gatekeeper for inflammation.
Annu. Rev. Physiol., 2013 , 75 (181-200).

426

340620

429

336123

430

336303

Waszkielewicz AM et al. Ion channels as drug targets in central nervous system disorders.
Curr. Med. Chem., 2013 , 20 (1241-85).

431

336287

434

346916

435

347077

Benemei S et al. TRPA1 and other TRP channels in migraine.
J Headache Pain, 2013 , 14 (71).

437

346854

438

346838

Yamamoto D et al. Insect pheromone behavior: fruit fly.
Methods Mol. Biol., 2013 , 1068 (261-72).

442

353607

Tsumura M et al. Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts.
PLoS ONE, 2013 , 8 (e82233).

444

354315

445

338704

446

331183

Chadha A et al. Dissection of gain control mechanisms in Drosophila mechanotransduction.
J. Neurosci., 2012 Sep 19 , 32 (13052-61).

447

329500

Vallin KS et al. N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor.
Bioorg. Med. Chem. Lett., 2012 Sep 1 , 22 (5485-92).

448

331854

Edelmayer RM et al. Activation of TRPA1 on dural afferents: a potential mechanism of headache pain.
Pain, 2012 Sep , 153 (1949-58).

449

331763

Ferrer-Montiel A et al. Advances in modulating thermosensory TRP channels.
Expert Opin Ther Pat, 2012 Sep , 22 (999-1017).

450

330376

451

332905

Earley S TRPA1 channels in the vasculature.
Br. J. Pharmacol., 2012 Sep , 167 (13-22).

452

334645

453

331702

455

334560

Keene AC et al. Optogenetic induction of aversive taste memory.
Neuroscience, 2012 Oct 11 , 222 (173-80).

456

332784

Patwardhan A et al. Receptor specificity defines algogenic properties of propofol and fospropofol.
Anesth. Analg., 2012 Oct , 115 (837-40).

458

337391

Jang Y et al. Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res., 2012 Oct , 35 (1823-30).

459

339116

Wang Y et al. Menthol inhibits the proliferation and motility of prostate cancer DU145 cells.
Pathol. Oncol. Res., 2012 Oct , 18 (903-10).

461

330720

463

331153

Nilius B et al. The transient receptor potential channel TRPA1: from gene to pathophysiology.
Pflugers Arch., 2012 Nov , 464 (425-58).

465

337106

466

338143

Knaapila A et al. Genetic analysis of chemosensory traits in human twins.
Chem. Senses, 2012 Nov , 37 (869-81).

467

338520

470

333156

Ortar G et al. Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds.
Bioorg. Med. Chem. Lett., 2012 May 15 , 22 (3535-9).

472

329997

Bianchi BR et al. Species comparison and pharmacological characterization of human, monkey, rat, and mouse TRPA1 channels.
J. Pharmacol. Exp. Ther., 2012 May , 341 (360-8).

473

333761

Fernandes ES et al. The functions of TRPA1 and TRPV1: moving away from sensory nerves.
Br. J. Pharmacol., 2012 May , 166 (510-21).

474

326130

476

334013

Shintaku K et al. Activation of transient receptor potential A1 by a non-pungent capsaicin-like compound, capsiate.
Br. J. Pharmacol., 2012 Mar , 165 (1476-86).

480

326186

Kanezaki M et al. Effect of cigarette smoking on cough reflex induced by TRPV1 and TRPA1 stimulations.
Respir Med, 2012 Mar , 106 (406-12).

481

328235

Preti D et al. TRP channels as therapeutic targets in airway disorders: a patent review.
Expert Opin Ther Pat, 2012 Jun , 22 (663-95).

484

333695

Bennett SM et al. Differences in the chemesthetic subqualities of capsaicin, ibuprofen, and olive oil.
Chem. Senses, 2012 Jun , 37 (471-8).

489

325248

492

330056

Gijsen HJ et al. Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists.
Bioorg. Med. Chem. Lett., 2012 Jan 15 , 22 (797-800).

493

326782

Bang S et al. Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.
Neurosci. Lett., 2012 Jan 11 , 506 (297-302).

496

324865

Raemdonck K et al. A role for sensory nerves in the late asthmatic response.
Thorax, 2012 Jan , 67 (19-25).

497

324538

501

327082

502

325697

504

327874

Koivisto A Sustained TRPA1 activation in vivo.
Acta Physiol (Oxf), 2012 Feb , 204 (248-54).

506

330542

507

330427

Alpizar YA et al. Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1.
Pflugers Arch., 2012 Dec 28 , ().

510

334406

Shen MY et al. Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2012 Dec , 303 (R1175-85).

511

338876

McClenaghan C et al. TRPA1 agonist activity of probenecid desensitizes channel responses: consequences for screening.
Assay Drug Dev Technol, 2012 Dec , 10 (533-41).

515

331815

Dong HW et al. Expression of transient receptor potential (TRP) channel mRNAs in the mouse olfactory bulb.
Neurosci. Lett., 2012 Aug 22 , 524 (49-54).

517

338872

Brozmanova M et al. Comparison of TRPA1-versus TRPV1-mediated cough in guinea pigs.
Eur. J. Pharmacol., 2012 Aug 15 , 689 (211-8).

519

329417

Premkumar LS et al. TRP channels and analgesia.
Life Sci., 2012 Aug 14 , ().

520

328231

521

338710

Kim YS et al. Expression of transient receptor potential ankyrin 1 in human dental pulp.
J Endod, 2012 Aug , 38 (1087-92).

522

328365

523

341233

Bharate SS et al. Modulation of thermoreceptor TRPM8 by cooling compounds.
ACS Chem Neurosci, 2012 Apr 18 , 3 (248-67).

525

328885

Komatsu T et al. Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner.
Pflugers Arch., 2012 Apr , 463 (549-59).

526

326969

Koseki J et al. Role of transient receptor potential ankyrin 1 in gastric accommodation in conscious guinea pigs.
J. Pharmacol. Exp. Ther., 2012 Apr , 341 (205-12).

528

333492

531

338118

Sample SJ et al. Functional adaptation in female rats: the role of estrogen signaling.
PLoS ONE, 2012 , 7 (e43215).

536

337716

538

337148

540

334507

Lennertz RC et al. TRPA1 mediates mechanical sensitization in nociceptors during inflammation.
PLoS ONE, 2012 , 7 (e43597).

541

332227

Motter AL et al. TRPA1 is a polyunsaturated fatty acid sensor in mammals.
PLoS ONE, 2012 , 7 (e38439).

544

331662

Ohkawara S et al. Methylglyoxal activates the human transient receptor potential ankyrin 1 channel.
J Toxicol Sci, 2012 , 37 (831-5).

549

329169

Lapointe TK et al. The role of TRPA1 in visceral inflammation and pain.
Channels (Austin), 2011 Nov-Dec , 5 (525-9).

551

320993

552

323374

553

323669

554

324934

Ye Y et al. Nerve growth factor links oral cancer progression, pain, and cachexia.
Mol. Cancer Ther., 2011 Sep , 10 (1667-76).

555

327842

Patil M et al. Cannabinoid receptor antagonists AM251 and AM630 activate TRPA1 in sensory neurons.
Neuropharmacology, 2011 Sep , 61 (778-88).

558

327884

Garrison SR et al. The dynamic TRPA1 channel: a suitable pharmacological pain target?
Curr Pharm Biotechnol, 2011 Oct , 12 (1689-97).

559

323900

560

323988

Brozmanova M et al. Preferential activation of the vagal nodose nociceptive subtype by TRPA1 agonists in the guinea pig esophagus.
Neurogastroenterol. Motil., 2011 Oct , 23 (e437-45).

561

324032

Mukhopadhyay I et al. Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.
J. Recept. Signal Transduct. Res., 2011 Oct , 31 (350-8).

562

323283

Engel MA et al. TRPA1 and substance P mediate colitis in mice.
Gastroenterology, 2011 Oct , 141 (1346-58).

563

323088

Takahashi N et al. TRPA1 underlies a sensing mechanism for O2.
Nat. Chem. Biol., 2011 Oct , 7 (701-11).

564

322991

565

320719

567

322811

Andrade EL et al. TRPA1 antagonists as potential analgesic drugs.
, 2011 Nov 15 , ().

568

324755

Cordero-Morales JF et al. Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.
Proc. Natl. Acad. Sci. U.S.A., 2011 Nov 15 , 108 (E1184-91).

569

320338

Brooks SM Perspective on the human cough reflex.
, 2011 Nov 10 , 7 (10).

571

320533

Alenmyr L et al. TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
Clin Physiol Funct Imaging, 2011 Nov , 31 (435-44).

576

317581

578

318948

Andrade EL et al. TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Am. J. Physiol. Renal Physiol., 2011 May , 300 (F1223-34).

579

318918

581

318905

Xiao B et al. Scratching the surface: a role of pain-sensing TRPA1 in itch.
Nat. Neurosci., 2011 May , 14 (540-2).

585

319484

Banke TG The dilated TRPA1 channel pore state is blocked by amiloride and analogues.
Brain Res., 2011 Mar 24 , 1381 (21-30).

587

319404

Terada Y et al. Specific hydroxy fatty acids in royal jelly activate TRPA1.
J. Agric. Food Chem., 2011 Mar 23 , 59 (2627-35).

589

316209

Banner KH et al. TRP channels: Emerging targets for respiratory disease.
, 2011 Mar 17 , ().

593

316428

Shen WL et al. Function of rhodopsin in temperature discrimination in Drosophila.
Science, 2011 Mar 11 , 331 (1333-6).

594

315726

Kim HY et al. Characterization of Dental Nociceptive Neurons.
, 2011 Mar 1 , ().

597

319054

Donlea JM et al. Inducing sleep by remote control facilitates memory consolidation in Drosophila.
Science, 2011 Jun 24 , 332 (1571-6).

601

317788

Vincent F et al. TRPV4 Agonists and Antagonists.
, 2011 Jun 14 , ().

604

318084

Mori N et al. Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2011 Jun , 300 (R1494-505).

608

319153

Malin S et al. TRPV1 and TRPA1 Function and Modulation Are Target Tissue Dependent.
J. Neurosci., 2011 Jul 20 , 31 (10516-28).

609

327839

Miyamoto R et al. Time- and concentration-dependent activation of TRPA1 by hydrogen sulfide in rat DRG neurons.
Neurosci. Lett., 2011 Jul 20 , 499 (137-42).

610

319258

614

322013

615

315531

616

319914

Akopian AN Regulation of nociceptive transmission at the periphery via TRPA1-TRPV1 interactions.
Curr Pharm Biotechnol, 2011 Jan 1 , 12 (89-94).

617

319912

Holzer P TRP channels in the digestive system.
Curr Pharm Biotechnol, 2011 Jan 1 , 12 (24-34).

619

316393

Yokoyama S et al. Molecular convergence of infrared vision in snakes.
Mol. Biol. Evol., 2011 Jan , 28 (45-8).

627

325267

Aubdool AA et al. Neurovascular aspects of skin neurogenic inflammation.
J. Investig. Dermatol. Symp. Proc., 2011 Dec , 15 (33-9).

628

325856

Stepanyan RS et al. TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.
J. Assoc. Res. Otolaryngol., 2011 Dec , 12 (729-40).

629

330188

Jain A et al. TRP-channel-specific cutaneous eicosanoid release patterns.
Pain, 2011 Dec , 152 (2765-72).

630

326380

631

323806

Brain SD TRPV1 and TRPA1 channels in inflammatory pain: elucidating mechanisms.
Ann. N. Y. Acad. Sci., 2011 Dec , 1245 (36-7).

632

320408

Zhong J et al. Umbellulone modulates TRP channels.
Pflugers Arch., 2011 Dec , 462 (861-70).

634

320773

Zhong J et al. Ligustilide: a novel TRPA1 modulator.
Pflugers Arch., 2011 Dec , 462 (841-9).

635

348457

Uhl GR et al. Menthol preference among smokers: association with TRPA1 variants.
Nicotine Tob. Res., 2011 Dec , 13 (1311-5).

636

320956

Gracheva EO et al. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats.
Nature, 2011 Aug 4 , 476 (88-91).

637

325497

Frasnelli J et al. Perception of specific trigeminal chemosensory agonists.
Neuroscience, 2011 Aug 25 , 189 (377-83).

640

322486

Tóth DM et al. Nociception, neurogenic inflammation and thermoregulation in TRPV1 knockdown transgenic mice.
Cell. Mol. Life Sci., 2011 Aug , 68 (2589-601).

641

324300

644

316699

Harrington AM et al. A novel role for TRPM8 in visceral afferent function.
, 2011 Apr 11 , ().

645

316945

Nilius B et al. Irritating channels: the case of TRPA1.
J. Physiol. (Lond.), 2011 Apr 1 , 589 (1543-9).

647

318452

Bobkov YV et al. The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings.
Biochim. Biophys. Acta, 2011 Apr , 1808 (1120-8).

649

318471

Schwartz ES et al. Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation.
Gastroenterology, 2011 Apr , 140 (1283-1291.e1-2).

650

320559

651

318992

Harteneck C et al. Synthetic modulators of TRP channel activity.
Adv. Exp. Med. Biol., 2011 , 704 (87-106).

652

321207

Bae YC et al. Ultrastructural basis for craniofacial sensory processing in the brainstem.
Int. Rev. Neurobiol., 2011 , 97 (99-141).

654

317978

Wetsel WC Sensing hot and cold with TRP channels.
Int J Hyperthermia, 2011 , 27 (388-98).

656

320527

657

323103

Leffler A et al. Activation of TRPA1 by membrane permeable local anesthetics.
Mol Pain, 2011 , 7 (62).

658

318979

Chung MK et al. Role of TRP channels in pain sensation.
Adv. Exp. Med. Biol., 2011 , 704 (615-36).

661

327835

Strassmaier T et al. Transient receptor potential A1 modulators.
Curr Top Med Chem, 2011 , 11 (2227-36).

662

327829

Nieto-Posadas A et al. TRP channel gating physiology.
Curr Top Med Chem, 2011 , 11 (2131-50).

663

323963

Neely GG et al. TrpA1 regulates thermal nociception in Drosophila.
PLoS ONE, 2011 , 6 (e24343).

664

327724

665

334111

Juszczak K et al. [Capsaicin and lidocaine usage in functional disorders of urinary bladder].
Folia Med Cracov, 2011 , 51 (91-8).

666

322821

668

319337

Rech JC et al. Recent advances in the biology and medicinal chemistry of TRPA1.
Future Med Chem, 2010 May , 2 (843-58).

669

339390

671

315966

675

322683