TRPA1
675 literature references associated to TRPA1
1
Touska F
et al.
Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay.
Temperature (Austin),
2016 Jan-Mar
, 3 (77-91).
2
Andrei SR
et al.
TRPA1 is functionally co-expressed with TRPV1 in cardiac muscle: Co-localization at z-discs, costameres and intercalated discs.
Channels (Austin),
2016
May
4
, (1-15).
3
McEntire DM
et al.
Pain transduction: a pharmacologic perspective.
Expert Rev Clin Pharmacol,
2016
May
23
, (1-12).
4
Babes A
et al.
Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.
J. Neurosci.,
2016
May
11
, 36 (5264-78).
5
Karaki S
et al.
Effects of ε-viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa.
Physiol Rep,
2016
May
, 4 ().
6
Cooper BY
et al.
Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors.
Neurotoxicology,
2016
May
, 54 (99-110).
7
Shapiro H
et al.
Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation.
Prostaglandins Leukot. Essent. Fatty Acids,
2016
Mar
9
, ().
8
Bertin S
et al.
The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1.
Gut,
2016
Jun
20
, ().
9
Payrits M
et al.
A novel 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime compound is a potent Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and V1) receptor antagonist.
Neuroscience,
2016
Jun
2
, 324 (151-62).
10
Meents JE
et al.
Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.
J. Physiol. (Lond.),
2016
Jun
16
, ().
11
Bahia PK
et al.
The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1.
J. Gen. Physiol.,
2016
Jun
, 147 (451-65).
12
Hamilton NB
et al.
Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia.
Nature,
2016
Jan
28
, 529 (523-7).
13
Verma VA
et al.
α-Aryl pyrrolidine sulfonamides as TRPA1 antagonists.
Bioorg. Med. Chem. Lett.,
2016
Jan
15
, 26 (495-8).
14
Borkum JM
Migraine Triggers and Oxidative Stress: A Narrative Review and Synthesis.
Headache,
2016
Jan
, 56 (12-35).
15
Mistretta FA
et al.
DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.
J. Pharmacol. Exp. Ther.,
2016
Jan
, 356 (200-11).
16
Snyder LM
et al.
An Unexpected Role for TRPV4 in Serotonin-Mediated Itch.
J. Invest. Dermatol.,
2016
Jan
, 136 (7-9).
17
Du EJ
et al.
TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.
PLoS Genet.,
2016
Jan
, 12 (e1005773).
18
Stueber T
et al.
Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity.
Anesthesiology,
2016
Feb
9
, ().
19
Das A
et al.
dTRPA1 in Non-circadian Neurons Modulates Temperature-Dependent Rhythmic Activity in Drosophila melanogaster.
J. Biol. Rhythms,
2016
Feb
11
, ().
20
El Karim IA
et al.
Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells.
J Endod,
2016
Feb
10
, ().
21
Brozmanova M
et al.
Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2016
Feb
1
, 310 (G215-23).
22
Chen S
et al.
TRP channel mediated neuronal activation and ablation in freely behaving zebrafish.
Nat. Methods,
2016
Feb
, 13 (147-50).
23
Ferreira LG
et al.
TRPing on the pore phenomenon: what do we know about transient receptor potential ion channel-related pore dilation up to now?
J. Bioenerg. Biomembr.,
2016
Feb
, 48 (1-12).
24
Kang K
Exceptionally high thermal sensitivity of rattlesnake TRPA1 correlates with peak current amplitude.
Biochim. Biophys. Acta,
2016
Feb
, 1858 (318-25).
25
Murphy TV
et al.
TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats.
Vascul. Pharmacol.,
2016
Apr
9
, ().
26
Devos FC
et al.
Neuro-immune interactions in chemical-induced airway hyperreactivity.
Eur. Respir. J.,
2016
Apr
28
, ().
27
Moriello AS
et al.
Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo.
CNS Neurol Disord Drug Targets,
2016
Apr
13
, ().
28
Jian T
et al.
TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch.
Neural Plast.,
2016
, 2016 (1682972).
29
Soldano A
et al.
Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila.
Elife,
2016
, 5 ().
30
Kanju P
et al.
Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.
Sci Rep,
2016
, 6 (26894).
31
Wu X
et al.
Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
PLoS ONE,
2016
, 11 (e0155577).
32
da Silva Serra I
et al.
Characterization of cutaneous and articular sensory neurons.
Mol Pain,
2016
, 12 ().
33
Zappia KJ
et al.
Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes.
PLoS ONE,
2016
, 11 (e0151602).
34
Ückert S
et al.
Expression and distribution of the transient receptor potential cationic channel ankyrin 1 (TRPA1) in the human vagina.
Int. J. Impot. Res.,
2015 Jan-Feb
, 27 (16-9).
35
Chen J
The evolutionary divergence of TRPA1 channel: heat-sensitive, cold-sensitive and temperature-insensitive.
Temperature (Austin),
2015 Apr-Jun
, 2 (158-9).
36
Laursen WJ
et al.
Species-specific temperature sensitivity of TRPA1.
Temperature (Austin),
2015 Apr-Jun
, 2 (214-26).
37
Ji RR
Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms?
Pulm Pharmacol Ther,
2015
Sep
6
, ().
38
Pradhananga S
et al.
Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.
Eur. J. Pharmacol.,
2015
Sep
5
, 762 (313-21).
39
Tatsumi E
et al.
Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury.
Neuroreport,
2015
Sep
30
, 26 (856-61).
40
Paulsen CE
et al.
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature,
2015
Sep
24
, 525 (552).
41
Asgar J
et al.
The role of TRPA1 in muscle pain and mechanical hypersensitivity under inflammatory conditions in rats.
Neuroscience,
2015
Sep
21
, 310 (206-215).
42
Brewster MS
et al.
How the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopy.
Bioessays,
2015
Sep
21
, ().
44
Billeter AT
et al.
TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Surgery,
2015
Sep
, 158 (646-54).
45
De Petrocellis L
et al.
Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel.
Pharmacol. Res.,
2015
Sep
, 99 (362-9).
46
Stenger B
et al.
Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents.
Arch. Toxicol.,
2015
Sep
, 89 (1631-43).
47
Nishimoto R
et al.
Propofol-induced pain sensation involves multiple mechanisms in sensory neurons.
Pflugers Arch.,
2015
Sep
, 467 (2011-20).
48
Xu ZH
et al.
Action of thymol on spontaneous excitatory transmission in adult rat spinal substantia gelatinosa neurons.
Neurosci. Lett.,
2015
Oct
8
, 606 (94-9).
49
Ujike A
et al.
Bidirectional effects of hydrogen sulfide via ATP-sensitive K(+) channels and transient receptor potential A1 channels in RIN14B cells.
Eur. J. Pharmacol.,
2015
Oct
5
, 764 (463-70).
50
Oda M
et al.
Chemical sensing properties of Takifugu TRPA1.
Neuroreport,
2015
Oct
21
, 26 (908-14).
51
Kichko TI
et al.
Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.
Am. J. Physiol. Lung Cell Mol. Physiol.,
2015
Oct
15
, 309 (L812-20).
52
Yu X
et al.
TRP channel functions in the gastrointestinal tract.
Semin Immunopathol,
2015
Oct
12
, ().
53
Patel R
et al.
Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci.,
2015
Oct
10
, ().
54
Hulse RP
et al.
Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.
Clin. Sci.,
2015
Oct
1
, 129 (741-56).
55
Patricio ES
et al.
Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice.
J. Invest. Dermatol.,
2015
Oct
, 135 (2484-91).
56
Barbagallo B
et al.
Temperature sensation in Drosophila.
Curr. Opin. Neurobiol.,
2015
Oct
, 34 (8-13).
57
Moilanen LJ
et al.
Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis.
Osteoarthr. Cartil.,
2015
Nov
, 23 (2017-26).
58
Okada Y
et al.
Transient Receptor Potential Channels and Corneal Stromal Inflammation.
Cornea,
2015
Nov
, 34 Suppl 11 (S136-41).
59
El Karim I
et al.
TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells.
Am. J. Pathol.,
2015
Nov
, 185 (2994-3002).
60
Mollanazar NK
et al.
Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?
Clin Rev Allergy Immunol,
2015
May
1
, ().
61
Witschas K
et al.
Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane.
Biochim. Biophys. Acta,
2015
May
, 1848 (1147-56).
62
Kim HG
et al.
The roles of thermal transient receptor potential channels in thermotactic behavior and in thermal acclimation in the red flour beetle, Tribolium castaneum.
J. Insect Physiol.,
2015
May
, 76 (47-55).
63
Horváth G
et al.
Effects of some natural carotenoids on TRPA1- and TRPV1-induced neurogenic inflammatory processes in vivo in the mouse skin.
J. Mol. Neurosci.,
2015
May
, 56 (113-21).
64
65
Gualdani R
et al.
Lipoic-based TRPA1/TRPV1 antagonist to treat orofacial pain.
ACS Chem Neurosci,
2015
Mar
18
, 6 (380-5).
66
Iosub AV
et al.
Palladium-catalyzed aerobic oxidative dehydrogenation of cyclohexenes to substituted arene derivatives.
J. Am. Chem. Soc.,
2015
Mar
18
, 137 (3454-7).
67
Liu Z
et al.
Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2015
Mar
15
, 308 (G482-8).
68
Del Prete D
et al.
Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands.
Bioorg. Med. Chem. Lett.,
2015
Mar
1
, 25 (1009-11).
69
Liu BY
et al.
Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8.
J. Appl. Physiol.,
2015
Mar
1
, 118 (635-45).
70
Jha A
et al.
A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?
Can. J. Physiol. Pharmacol.,
2015
Mar
, 93 (171-6).
71
Urata K
et al.
Involvement of TRPV1 and TRPA1 in incisional intraoral and extraoral pain.
J. Dent. Res.,
2015
Mar
, 94 (446-54).
72
Peng G
et al.
Evolution of TRP channels inferred by their classification in diverse animal species.
Mol. Phylogenet. Evol.,
2015
Mar
, 84 (145-57).
73
Sałat K
et al.
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
J Zhejiang Univ Sci B,
2015
Mar
, 16 (167-78).
74
Hsu CC
et al.
Role of calcium ions in the positive interaction between TRPA1 and TRPV1 channels in bronchopulmonary sensory neurons.
J. Appl. Physiol.,
2015
Jun
15
, 118 (1533-43).
75
Andersson DA
et al.
Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE.
J. Biol. Chem.,
2015
Jun
12
, 290 (15185-96).
77
Mori Y
et al.
Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation.
Pflugers Arch.,
2015
Jul
7
, ().
78
Green EW
et al.
Drosophila circadian rhythms in seminatural environments: Summer afternoon component is not an artifact and requires TrpA1 channels.
Proc. Natl. Acad. Sci. U.S.A.,
2015
Jul
14
, 112 (8702-7).
79
Peng G
et al.
Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1.
Cell Rep,
2015
Jul
14
, 12 (190-202).
80
Morita T
et al.
HTR7 Mediates Serotonergic Acute and Chronic Itch.
Neuron,
2015
Jul
1
, 87 (124-38).
81
Meng Q
et al.
Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers.
Am. J. Physiol., Cell Physiol.,
2015
Jul
1
, 309 (C1-10).
82
Sherkheli MA
et al.
Borneol inhibits TRPA1, a proinflammatory and noxious pain-sensing cation channel.
Pak J Pharm Sci,
2015
Jul
, 28 (1357-63).
83
Kimball C
et al.
The Pore Loop Domain of TRPV1 Is Required for Its Activation by the Volatile Anesthetics Chloroform and Isoflurane.
Mol. Pharmacol.,
2015
Jul
, 88 (131-8).
84
Deberry JJ
et al.
Artemin Immunotherapy Is Effective in Preventing and Reversing Cystitis-Induced Bladder Hyperalgesia via TRPA1 Regulation.
J Pain,
2015
Jul
, 16 (628-36).
85
Zhu Y
et al.
Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Br. J. Pharmacol.,
2015
Jul
, 172 (3495-509).
86
Nassini R
et al.
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Br. J. Pharmacol.,
2015
Jul
, 172 (3397-411).
87
Sullivan MN
et al.
Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.
Sci Signal,
2015
Jan
6
, 8 (ra2).
88
Ohara K
et al.
Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil.
J. Biol. Chem.,
2015
Jan
30
, 290 (3161-71).
89
Palkar R
et al.
The molecular and cellular basis of thermosensation in mammals.
Curr. Opin. Neurobiol.,
2015
Jan
23
, 34C (14-19).
90
Pinheiro Fde V
et al.
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain.
Eur. J. Pharmacol.,
2015
Jan
15
, 747 (105-13).
91
Canner JP
et al.
Developmental regulation of trigeminal TRPA1 by the cornea.
Invest. Ophthalmol. Vis. Sci.,
2015
Jan
, 56 (29-36).
92
Lindsay CD
et al.
Potency of irritation by benzylidenemalononitriles in humans correlates with TRPA1 ion channel activation.
R Soc Open Sci,
2015
Jan
, 2 (140160).
93
Huang BX
et al.
[Expressions of transient receptor potential A1 and related inflammatory factors in the rat model of prostatic inflammation].
Zhonghua Nan Ke Xue,
2015
Jan
, 21 (23-30).
94
Kurogi M
et al.
Auto-oxidation products of epigallocatechin gallate activate TRPA1 and TRPV1 in sensory neurons.
Chem. Senses,
2015
Jan
, 40 (27-46).
95
Yang YS
et al.
Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus.
Acta Derm. Venereol.,
2015
Jan
, 95 (20-4).
96
Zíma V
et al.
Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.
Neuropharmacology,
2015
Feb
25
, 93C (294-307).
97
Yrbas ML
et al.
Pharmacological mechanism underlying the antinociceptive activity of vanillic acid.
Pharmacol. Biochem. Behav.,
2015
Feb
21
, 132 (88-95).
98
Weyer AD
et al.
Loosening Pain's Grip by Tightening TRPV1-TRPA1 Interactions.
Neuron,
2015
Feb
18
, 85 (661-3).
99
Weng HJ
et al.
Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Neuron,
2015
Feb
18
, 85 (833-46).
100
Lin YJ
et al.
A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents.
J. Appl. Physiol.,
2015
Feb
1
, 118 (273-81).
101
Kichko TI
et al.
Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea.
Anesth. Analg.,
2015
Feb
, 120 (467-71).
102
Zielińska M
et al.
Role of transient receptor potential channels in intestinal inflammation and visceral pain: novel targets in inflammatory bowel diseases.
Inflamm. Bowel Dis.,
2015
Feb
, 21 (419-27).
103
Srebro DP
et al.
TRPA1, NMDA receptors and nitric oxide mediate mechanical hyperalgesia induced by local injection of magnesium sulfate into the rat hind paw.
Physiol. Behav.,
2015
Feb
, 139 (267-73).
104
Terada Y
et al.
Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis.
J. Neurosci. Res.,
2015
Feb
, 93 (361-9).
105
Silva RB
et al.
Spinal blockage of P/Q- or N-type voltage-gated calcium channels modulates functional and symptomatic changes related to haemorrhagic cystitis in mice.
Br. J. Pharmacol.,
2015
Feb
, 172 (924-39).
106
Hooper JS
et al.
Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin and ATP in Sprague Dawley rats.
J. Appl. Physiol.,
2015
Dec
30
, (jap.00944.2015).
107
Pires PW
et al.
Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.
Am. J. Physiol. Heart Circ. Physiol.,
2015
Dec
15
, 309 (H2031-41).
108
Bais S
et al.
Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni.
PLoS Negl Trop Dis,
2015
Dec
, 9 (e0004295).
109
Park J
et al.
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
J. Neurochem.,
2015
Dec
, 135 (987-97).
110
Deering-Rice CE
et al.
Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma.
Am. J. Respir. Cell Mol. Biol.,
2015
Dec
, 53 (893-901).
111
Terada Y
et al.
Structure-Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard.
J. Nat. Prod.,
2015
Aug
28
, 78 (1937-41).
112
Nozadze I
et al.
Role of thermo TRPA1 and TRPV1 channels in heat, cold, and mechanical nociception of rats.
Behav Pharmacol,
2015
Aug
13
, ().
113
Zou Q
et al.
Transient Receptor Potential Channel Opening Releases Endogenous Acetylcholine, which Contributes to Endothelium-Dependent Relaxation Induced by Mild Hypothermia in Spontaneously Hypertensive Rat but Not Wistar-Kyoto Rat Arteries.
J. Pharmacol. Exp. Ther.,
2015
Aug
, 354 (121-30).
114
Cenac N
et al.
Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.
Gastroenterology,
2015
Aug
, 149 (433-44.e7).
115
Carpi S
et al.
AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells.
Anticancer Drugs,
2015
Aug
, 26 (754-62).
116
Tani M
et al.
Long-lasting facilitation of respiratory rhythm by treatment with TRPA1 agonist, cinnamaldehyde.
J. Neurophysiol.,
2015
Aug
, 114 (989-98).
117
Wei JJ
et al.
A TRPA1 channel that senses thermal stimulus and irritating chemicals in Helicoverpa armigera.
Insect Mol. Biol.,
2015
Aug
, 24 (412-21).
118
Paulsen CE
et al.
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature,
2015
Apr
8
, ().
119
Shi HL
et al.
Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction.
World J. Gastroenterol.,
2015
Apr
28
, 21 (4852-63).
120
Clapham DE
Structural biology: Pain-sensing TRPA1 channel resolved.
Nature,
2015
Apr
23
, 520 (439-41).
121
Uvin P
et al.
Essential Role of Transient Receptor Potential M8 (TRPM8) in a Model of Acute Cold-induced Urinary Urgency.
Eur. Urol.,
2015
Apr
2
, ().
122
Katagiri A
et al.
Evidence for TRPA1 involvement in central neural mechanisms in a rat model of dry eye.
Neuroscience,
2015
Apr
2
, 290 (204-13).
123
Kang Q
et al.
Spontaneous L-glutamate release enhancement in rat substantia gelatinosa neurons by (-)-carvone and (+)-carvone which activate different types of TRP channel.
Biochem. Biophys. Res. Commun.,
2015
Apr
10
, 459 (498-503).
124
Kubota K
et al.
Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2015
Apr
1
, 308 (G579-90).
125
Li F
et al.
Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice.
Anesthesiology,
2015
Apr
, 122 (768-75).
126
Miyano K
et al.
Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
Anesth. Analg.,
2015
Apr
, 120 (790-8).
127
Lehto SG
et al.
AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia.
Naunyn Schmiedebergs Arch. Pharmacol.,
2015
Apr
, 388 (465-76).
128
Chen J
et al.
TRPA1 as a drug target--promise and challenges.
Naunyn Schmiedebergs Arch. Pharmacol.,
2015
Apr
, 388 (451-63).
129
Son GY
et al.
Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.
Arch. Oral Biol.,
2015
Apr
, 60 (526-32).
130
Shibukawa Y
et al.
Odontoblasts as sensory receptors: transient receptor potential channels, pannexin-1, and ionotropic ATP receptors mediate intercellular odontoblast-neuron signal transduction.
Pflugers Arch.,
2015
Apr
, 467 (843-63).
131
Moilanen LJ
et al.
Urate crystal induced inflammation and joint pain are reduced in transient receptor potential ankyrin 1 deficient mice - potential role for transient receptor potential ankyrin 1 in gout.
PLoS ONE,
2015
, 10 (e0117770).
132
Wang C
et al.
Wu-Tou Decoction Inhibits Chronic Inflammatory Pain in Mice: Participation of TRPV1 and TRPA1 Ion Channels.
Biomed Res Int,
2015
, 2015 (328707).
133
Sinha S
et al.
Propofol Causes Vasodilation In Vivo via TRPA1 Ion Channels: Role of Nitric Oxide and BKCa Channels.
PLoS ONE,
2015
, 10 (e0122189).
134
Kozai D
et al.
Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels.
Curr Neuropharmacol,
2015
, 13 (266-78).
135
Morgan K
et al.
Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.
Biosci. Rep.,
2015
, 35 ().
136
Liu C
et al.
Cell cycle control, DNA damage repair, and apoptosis-related pathways control pre-ameloblasts differentiation during tooth development.
BMC Genomics,
2015
, 16 (592).
137
Das A
et al.
dTRPA1 Modulates Afternoon Peak of Activity of Fruit Flies Drosophila melanogaster.
PLoS ONE,
2015
, 10 (e0134213).
138
Carson C
et al.
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
PLoS ONE,
2015
, 10 (e0127498).
140
Lötsch J
et al.
Multimodal distribution of human cold pain thresholds.
PLoS ONE,
2015
, 10 (e0125822).
141
Kurohane K
et al.
Adjuvant Effect of an Alternative Plasticizer, Diisopropyl Adipate, on a Contact Hypersensitivity Mouse Model: Link with Sensory Ion Channel TRPA1 Activation.
Biol. Pharm. Bull.,
2015
, 38 (1054-62).
142
Watanabe T
et al.
Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods.
J. Nutr. Sci. Vitaminol.,
2015
, 61 Suppl (S86-8).
143
Mancuso G
et al.
Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.
Molecules,
2015
, 20 (18907-22).
144
Gallego-Martin T
et al.
Experimental Observations on the Biological Significance of Hydrogen Sulfide in Carotid Body Chemoreception.
Adv. Exp. Med. Biol.,
2015
, 860 (9-16).
145
Terada Y
et al.
H2S and Pain: A Novel Aspect for Processing of Somatic, Visceral and Neuropathic Pain Signals.
Handb Exp Pharmacol,
2015
, 230 (217-30).
146
Park JH
et al.
Oxaliplatin-Induced Peripheral Neuropathy via TRPA1 Stimulation in Mice Dorsal Root Ganglion Is Correlated with Aluminum Accumulation.
PLoS ONE,
2015
, 10 (e0124875).
147
Fischer MJ
et al.
Formalin evokes calcium transients from the endoplasmatic reticulum.
PLoS ONE,
2015
, 10 (e0123762).
148
Camacho S
et al.
Anti-obesity and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin secretion and functional impact on food intake and gastric emptying.
Sci Rep,
2015
, 5 (7919).
149
Curtright A
et al.
Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery.
PLoS ONE,
2015
, 10 (e0116766).
150
Mueller-Tribbensee SM
et al.
Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice.
PLoS ONE,
2015
, 10 (e0128242).
151
Suslak TJ
et al.
Piezo Is Essential for Amiloride-Sensitive Stretch-Activated Mechanotransduction in Larval Drosophila Dorsal Bipolar Dendritic Sensory Neurons.
PLoS ONE,
2015
, 10 (e0130969).
152
Bencsik T
et al.
High-Concentration Piperine: Capsaicin-Sensitive and -Insensitive Effects on Isolated Organs.
Pharmacology,
2015
, 96 (86-9).
153
Ruparel S
et al.
Released lipids regulate transient receptor potential channel (TRP)-dependent oral cancer pain.
Mol Pain,
2015
, 11 (30).
154
Moon H
et al.
Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa.
PLoS ONE,
2015
, 10 (e0127060).
155
Hatakeyama Y
et al.
Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons.
Mol Pain,
2015
, 11 (24).
156
Yamanaka M
et al.
In vivo patch-clamp analysis of the antinociceptive actions of TRPA1 activation in the spinal dorsal horn.
Mol Pain,
2015
, 11 (20).
157
Ikeda-Miyagawa Y
et al.
Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons.
Mol Pain,
2015
, 11 (8).
158
Preti D
et al.
Transient receptor potential ankyrin 1 (TRPA1) antagonists.
Pharm Pat Anal,
2015
, 4 (75-94).
159
Brizzi A
et al.
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
Bioorg. Med. Chem.,
2014
Sep
1
, 22 (4770-83).
160
Okada Y
et al.
TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma.
Lab. Invest.,
2014
Sep
, 94 (1030-41).
161
Egbuniwe O
et al.
TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.
J. Dent. Res.,
2014
Sep
, 93 (911-7).
162
Greaves E
et al.
Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis.
J. Clin. Endocrinol. Metab.,
2014
Sep
, 99 (E1738-43).
163
Garrison SR
et al.
Contribution of transient receptor potential ankyrin 1 to chronic pain in aged mice with complete Freund's adjuvant-induced arthritis.
,
2014
Sep
, 66 (2380-90).
164
Fusi C
et al.
Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer.
J. Invest. Dermatol.,
2014
Sep
, 134 (2408-17).
165
Sadaf S
et al.
Serotonergic neurons of the Drosophila air-puff-stimulated flight circuit.
J. Biosci.,
2014
Sep
, 39 (575-83).
166
Straub RH
TRPV1, TRPA1, and TRPM8 channels in inflammation, energy redirection, and water retention: role in chronic inflammatory diseases with an evolutionary perspective.
J. Mol. Med.,
2014
Sep
, 92 (925-37).
167
de Moura JC
et al.
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice.
Br. J. Pharmacol.,
2014
Sep
, 171 (4289-99).
168
Avenali L
et al.
Annexin A2 regulates TRPA1-dependent nociception.
J. Neurosci.,
2014
Oct
29
, 34 (14506-16).
169
Emery EC
et al.
Stimulation of glucagon-like peptide-1 secretion downstream of the ligand-gated ion channel TRPA1.
Diabetes,
2014
Oct
16
, ().
170
Pazienza V
et al.
The TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling.
Am. J. Physiol. Heart Circ. Physiol.,
2014
Oct
1
, 307 (H939-44).
171
Zhang X
et al.
Activation of TRPC channels contributes to OA-NO2-induced responses in guinea-pig dorsal root ganglion neurons.
J. Physiol. (Lond.),
2014
Oct
1
, 592 (4297-312).
172
Deering-Rice CE
et al.
Drofenine: A 2-APB Analogue with Greater Selectivity for Human TRPV3.
Pharmacol Res Perspect,
2014
Oct
, 2 (e00062).
173
Saarnilehto M
et al.
Contact sensitizer 2,4-dinitrochlorobenzene is a highly potent human TRPA1 agonist.
Allergy,
2014
Oct
, 69 (1424-7).
174
Olsen RV
et al.
Somatosensory and vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers.
Eur J Pain,
2014
Oct
, 18 (1333-42).
175
Brenner DS
et al.
A dynamic set point for thermal adaptation requires phospholipase C-mediated regulation of TRPM8 in vivo.
Pain,
2014
Oct
, 155 (2124-33).
176
Shimizu S
et al.
Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Eur. J. Pharmacol.,
2014
Nov
5
, 742 (22-30).
177
Moparthi L
et al.
Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain.
Proc. Natl. Acad. Sci. U.S.A.,
2014
Nov
25
, 111 (16901-6).
178
Iannotti FA
et al.
Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability.
ACS Chem Neurosci,
2014
Nov
19
, 5 (1131-41).
179
Banzawa N
et al.
Molecular basis determining inhibition/activation of nociceptive receptor TRPA1 protein: a single amino acid dictates species-specific actions of the most potent mammalian TRPA1 antagonist.
J. Biol. Chem.,
2014
Nov
14
, 289 (31927-39).
180
Oguri G
et al.
Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.
Am. J. Physiol. Heart Circ. Physiol.,
2014
Nov
1
, 307 (H1339-52).
181
Su KH
et al.
The essential role of transient receptor potential vanilloid 1 in simvastatin-induced activation of endothelial nitric oxide synthase and angiogenesis.
Acta Physiol (Oxf),
2014
Nov
, 212 (191-204).
182
Hegarty DM
et al.
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats.
J. Chem. Neuroanat.,
2014
Nov
, 61-62 (1-12).
183
Furuta A
et al.
Cross-sensitization mechanisms between colon and bladder via transient receptor potential A1 stimulation in rats.
Int Urogynecol J,
2014
Nov
, 25 (1575-81).
184
Alvarez-Collazo J
et al.
Cinnamaldehyde inhibits L-type calcium channels in mouse ventricular cardiomyocytes and vascular smooth muscle cells.
Pflugers Arch.,
2014
Nov
, 466 (2089-99).
185
Sun W
et al.
Enhanced production of nitric oxide in A549 cells through activation of TRPA1 ion channel by cold stress.
Nitric Oxide,
2014
May
9
, 40C (31-35).
186
Cheah EY
et al.
Acrolein relaxes mouse isolated tracheal smooth muscle via a TRPA1-dependent mechanism.
Biochem. Pharmacol.,
2014
May
1
, 89 (148-56).
187
Franken J
et al.
TRP channels in lower urinary tract dysfunction.
Br. J. Pharmacol.,
2014
May
, 171 (2537-51).
188
Colombo M
et al.
Effect of free thymol on differential gene expression in gastric mucosa of the young pig.
Animal,
2014
May
, 8 (786-91).
189
Nakajima S
et al.
Unsaturated aldehydes induce CCK secretion via TRPA1 in STC-1 cells.
Mol Nutr Food Res,
2014
May
, 58 (1042-51).
190
Gautier M
et al.
New insights into pharmacological tools to TR(i)P cancer up.
Br. J. Pharmacol.,
2014
May
, 171 (2582-92).
191
Benemei S
et al.
The TRPA1 channel in migraine mechanism and treatment.
Br. J. Pharmacol.,
2014
May
, 171 (2552-67).
192
Kaneko Y
et al.
Transient receptor potential (TRP) channels: a clinical perspective.
Br. J. Pharmacol.,
2014
May
, 171 (2474-507).
193
Chung G
et al.
Activation of transient receptor potential ankyrin 1 by eugenol.
Neuroscience,
2014
Mar
7
, 261 (153-60).
194
Gui J
et al.
A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Curr. Biol.,
2014
Mar
3
, 24 (473-83).
195
de Oliveira C
et al.
Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents.
J. Neurosci.,
2014
Mar
26
, 34 (4445-52).
196
Birrell MA
et al.
Tiotropium modulates transient receptor potential V1 (TRPV1) in airway sensory nerves: A beneficial off-target effect?
J. Allergy Clin. Immunol.,
2014
Mar
, 133 (679-87.e9).
197
Pittman SK
et al.
Paclitaxel alters the evoked release of calcitonin gene-related peptide from rat sensory neurons in culture.
Exp. Neurol.,
2014
Mar
, 253 (146-53).
198
Due MR
et al.
Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat.
J. Neurochem.,
2014
Mar
, 128 (776-86).
199
Ulasli M
et al.
The effects of Nigella sativa (Ns), Anthemis hyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family.
Mol. Biol. Rep.,
2014
Mar
, 41 (1703-11).
200
Yin S
et al.
LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.
Br. J. Pharmacol.,
2014
Mar
, 171 (1510-20).
201
Tran VT
et al.
Mechanotransduction channels of the trabecular meshwork.
Curr. Eye Res.,
2014
Mar
, 39 (291-303).
202
Copeland KW
et al.
Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
Bioorg. Med. Chem. Lett.,
2014
Jun
6
, ().
203
Dall'Acqua MC
et al.
The contribution of transient receptor potential ankyrin 1 (TRPA1) to the in vivo nociceptive effects of prostaglandin E₂.
Life Sci.,
2014
Jun
6
, 105 (7-13).
204
Huynh KW
et al.
Application of Amphipols for Structure-Functional Analysis of TRP Channels.
J. Membr. Biol.,
2014
Jun
4
, ().
205
Jabba S
et al.
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six.
Neuron,
2014
Jun
4
, 82 (1017-31).
206
Zappia KJ
et al.
Cold hypersensitivity increases with age in mice with sickle cell disease.
Pain,
2014
Jun
3
, ().
207
Rooney L
et al.
Discovery, Optimization, and Biological Evaluation of 5-(2-(Trifluoromethyl)phenyl)indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists.
J. Med. Chem.,
2014
Jun
26
, 57 (5129-40).
208
Bennett DL
et al.
Painful and painless channelopathies.
Lancet Neurol,
2014
Jun
, 13 (587-99).
209
Lau BK
et al.
Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons.
Br. J. Pharmacol.,
2014
Jun
, 171 (2803-13).
210
Minagawa T
et al.
The role of transient receptor potential ankyrin 1 (TRPA1) channel in activation of single unit mechanosensitive bladder afferent activities in the rat.
Neurourol. Urodyn.,
2014
Jun
, 33 (544-9).
211
Deruyver Y
et al.
Transient receptor potential channel modulators as pharmacological treatments for lower urinary tract symptoms (LUTS): myth or reality?
BJU Int.,
2014
Jul
25
, ().
212
Malsch P
et al.
Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.
J. Neurosci.,
2014
Jul
23
, 34 (9845-56).
213
Laliberté S
et al.
Discovery of a series of aryl-N-(3-(alkylamino)-5-(trifluoromethyl)phenyl)benzamides as TRPA1 antagonists.
Bioorg. Med. Chem. Lett.,
2014
Jul
15
, 24 (3204-6).
214
Hu YJ
et al.
Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists.
Bioorg. Med. Chem. Lett.,
2014
Jul
15
, 24 (3199-203).
215
Zhang W
et al.
The effect of intrathecal administration TRPA1 antagonists in a rat model of neuropathic pain.
Anesth. Analg.,
2014
Jul
, 119 (179-85).
216
Trevisan G
et al.
TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout.
Free Radic. Biol. Med.,
2014
Jul
, 72 (200-9).
217
Trevisan G
et al.
Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
Naunyn Schmiedebergs Arch. Pharmacol.,
2014
Jul
, 387 (679-89).
218
Deberry JJ
et al.
TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis.
Pain,
2014
Jul
, 155 (1280-7).
219
Wan X
et al.
Bimodal voltage dependence of TRPA1: mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation.
Pflugers Arch.,
2014
Jul
, 466 (1273-87).
220
Saito S
et al.
Heat and noxious chemical sensor, chicken TRPA1, as a target of bird repellents and identification of its structural determinants by multispecies functional comparison.
Mol. Biol. Evol.,
2014
Jan
7
, ().
221
Kurganov E
et al.
Heat and AITC activate green anole TRPA1 in a membrane-delimited manner.
Pflugers Arch.,
2014
Jan
3
, ().
222
Teichert RW
et al.
Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass.
Proc. Natl. Acad. Sci. U.S.A.,
2014
Jan
27
, ().
223
Meseguer V
et al.
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.
Nat Commun,
2014
Jan
20
, 5 (3125).
224
Cho HJ
et al.
Identification of enteroendocrine cells that express TRPA1 channels in the mouse intestine.
Cell Tissue Res.,
2014
Jan
18
, ().
225
Kojima R
et al.
Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain.
Eur. J. Pharmacol.,
2014
Jan
15
, 723 (288-93).
226
Gohlke BO
et al.
SuperPain--a resource on pain-relieving compounds targeting ion channels.
Nucleic Acids Res.,
2014
Jan
1
, 42 (D1107-12).
227
Hunter GL
et al.
Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure.
Development,
2014
Jan
, 141 (325-34).
228
Zhang X
et al.
Nitro-oleic acid desensitizes TRPA1 and TRPV1 agonist responses in adult rat DRG neurons.
Exp. Neurol.,
2014
Jan
, 251 (12-21).
229
Kozai D
et al.
Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators.
Mol. Pharmacol.,
2014
Jan
, 85 (175-85).
230
Abdullah H
et al.
Rhinovirus upregulates transient receptor potential channels in a human neuronal cell line: implications for respiratory virus-induced cough reflex sensitivity.
Thorax,
2014
Jan
, 69 (46-54).
231
Takaishi M
et al.
Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity.
J Physiol Sci,
2014
Jan
, 64 (47-57).
232
Brenneis C
et al.
Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.
Br. J. Pharmacol.,
2014
Jan
, 171 (438-51).
233
Terada Y
et al.
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.
J. Nat. Prod.,
2014
Feb
28
, 77 (285-97).
234
Bellono NW
et al.
UV light activates a Gαq/11-coupled phototransduction pathway in human melanocytes.
J. Gen. Physiol.,
2014
Feb
, 143 (203-14).
235
Cevikbas F
et al.
A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.
J. Allergy Clin. Immunol.,
2014
Feb
, 133 (448-60).
236
Spahn V
et al.
Modulation of transient receptor vanilloid 1 activity by transient receptor potential ankyrin 1.
Mol. Pharmacol.,
2014
Feb
, 85 (335-44).
237
Du GJ
et al.
The combination of TRPM8 and TRPA1 expression causes an invasive phenotype in lung cancer.
Tumour Biol.,
2014
Feb
, 35 (1251-61).
238
Devesa I
et al.
Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling.
Eur. J. Neurosci.,
2014
Feb
, 39 (353-62).
239
Barabas ME
et al.
Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice.
J. Biol. Chem.,
2014
Dec
5
, 289 (34241-9).
240
Amato A
et al.
Involvement of cholinergic nicotinic receptors in the menthol-induced gastric relaxation.
Eur. J. Pharmacol.,
2014
Dec
15
, 745 (129-34).
241
Luo QT
et al.
Carvacrol presynaptically enhances spontaneous excitatory transmission and produces outward current in adult rat spinal substantia gelatinosa neurons.
Brain Res.,
2014
Dec
10
, 1592 (44-54).
242
Ortar G
et al.
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels.
Bioorg. Med. Chem. Lett.,
2014
Dec
1
, 24 (5507-11).
243
Borrelli F
et al.
Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.
Carcinogenesis,
2014
Dec
, 35 (2787-97).
244
Sasaki A
et al.
A mouse model of peripheral postischemic dysesthesia: involvement of reperfusion-induced oxidative stress and TRPA1 channel.
J. Pharmacol. Exp. Ther.,
2014
Dec
, 351 (568-75).
245
Lieu T
et al.
The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Gastroenterology,
2014
Dec
, 147 (1417-28).
246
Chen Y
et al.
TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.
Pain,
2014
Dec
, 155 (2662-72).
247
Honda K
et al.
TRPA1 contributes to capsaicin-induced facial cold hyperalgesia in rats.
Eur. J. Oral Sci.,
2014
Dec
, 122 (391-6).
248
Fischer MJ
et al.
Direct evidence for functional TRPV1/TRPA1 heteromers.
Pflugers Arch.,
2014
Dec
, 466 (2229-41).
249
Rofes L
et al.
Effect of oral piperine on the swallow response of patients with oropharyngeal dysphagia.
J. Gastroenterol.,
2014
Dec
, 49 (1517-23).
250
Galili DS
et al.
Converging circuits mediate temperature and shock aversive olfactory conditioning in Drosophila.
Curr. Biol.,
2014
Aug
4
, 24 (1712-22).
251
Kozai D
et al.
Redox regulation of transient receptor potential channels.
Antioxid. Redox Signal.,
2014
Aug
20
, 21 (971-86).
252
Suzuki H
et al.
The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.
Am. J. Physiol., Cell Physiol.,
2014
Aug
15
, 307 (C384-94).
253
Terada Y
et al.
Sulphur-containing compounds of durian activate the thermogenesis-inducing receptors TRPA1 and TRPV1.
Food Chem,
2014
Aug
15
, 157 (213-20).
254
Lee KJ
et al.
Mouse monoclonal antibodies to transient receptor potential ankyrin 1 act as antagonists of multiple modes of channel activation.
J. Pharmacol. Exp. Ther.,
2014
Aug
, 350 (223-31).
255
Schreiner BS
et al.
Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons.
Eur. J. Pharmacol.,
2014
Apr
5
, 728 (48-58).
256
Hagenacker T
et al.
Icilin reduces voltage-gated calcium channel currents in naïve and injured DRG neurons in the rat spinal nerve ligation model.
Brain Res.,
2014
Apr
4
, 1557 (171-9).
257
Themistocleous AC
et al.
The clinical approach to small fibre neuropathy and painful channelopathy.
Pract Neurol,
2014
Apr
28
, ().
258
Park CK
et al.
Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
Neuron,
2014
Apr
2
, 82 (47-54).
259
Sato A
et al.
Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori.
Proc. Natl. Acad. Sci. U.S.A.,
2014
Apr
1
, 111 (E1249-55).
260
Takahashi N
et al.
The O(2)-sensing TRPA1 channel illustrates the significance of vagal nerves in cardio-respiratory adaptation to hypoxia.
Acta Physiol (Oxf),
2014
Apr
, 210 (705-7).
261
Soya M
et al.
Plasma membrane stretch activates transient receptor potential vanilloid and ankyrin channels in Merkel cells from hamster buccal mucosa.
Cell Calcium,
2014
Apr
, 55 (208-18).
262
Schulze A
et al.
Transient receptor potential ankyrin 1 (TRPA1) channel activation by the thienopyridine-type drugs ticlopidine, clopidogrel, and prasugrel.
Cell Calcium,
2014
Apr
, 55 (200-7).
263
Geppetti P
et al.
Transient receptor potential channels and occupational exposure.
Curr Opin Allergy Clin Immunol,
2014
Apr
, 14 (77-83).
264
Michot B
et al.
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
Neuropharmacology,
2014
Apr
, 79 (432-43).
265
Pokorski M
et al.
The hypoxic ventilatory response and TRPA1 antagonism in conscious mice.
Acta Physiol (Oxf),
2014
Apr
, 210 (928-38).
266
Albers KM
et al.
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Mol Pain,
2014
, 10 (31).
267
Steinberg X
et al.
A structural view of ligand-dependent activation in thermoTRP channels.
Front Physiol,
2014
, 5 (171).
268
Schütz M
et al.
Consequences of a human TRPA1 genetic variant on the perception of nociceptive and Olfactory Stimuli.
PLoS ONE,
2014
, 9 (e95592).
269
Boukalova S
et al.
Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?
Physiol Res,
2014
, 63 Suppl 1 (S205-13).
270
Redmond WJ
et al.
Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1.
PeerJ,
2014
, 2 (e248).
271
Fernandes VS
et al.
Hydrogen sulfide plays a key role in the inhibitory neurotransmission to the pig intravesical ureter.
PLoS ONE,
2014
, 9 (e113580).
272
Ren AJ
et al.
ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.
Nat Commun,
2014
, 5 (4984).
273
Cohen MR
et al.
Structure of thermally activated TRP channels.
Curr Top Membr,
2014
, 74 (181-211).
274
Laursen WJ
et al.
TRPA1 channels: chemical and temperature sensitivity.
Curr Top Membr,
2014
, 74 (89-112).
276
Kun J
et al.
Upregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective roles.
PLoS ONE,
2014
, 9 (e108164).
277
Barthó L
et al.
Smooth muscle-depressant activity of AP-18, a putative TRPA1 antagonist in the guinea pig intestine.
Pharmacology,
2014
, 94 (131-4).
278
Miyakawa T
et al.
Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats.
Mol Pain,
2014
, 10 (58).
279
Moldenhauer H
et al.
The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole.
PLoS ONE,
2014
, 9 (e106776).
282
Shimizu S
et al.
TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters).
Handb Exp Pharmacol,
2014
, 223 (767-94).
283
Winkler CW
et al.
Location is everything: let-7b microRNA and TLR7 signaling results in a painful TRP.
Sci Signal,
2014
, 7 (pe14).
284
Mizuno K
et al.
Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat.
J. Pharmacol. Sci.,
2014
, 125 (91-8).
286
Ruan T
et al.
Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors.
PLoS ONE,
2014
, 9 (e91763).
287
Kim MJ
et al.
Selective activation of hTRPV1 by N-geranyl cyclopropylcarboxamide, an amiloride-insensitive salt taste enhancer.
PLoS ONE,
2014
, 9 (e89062).
288
Anderson EM
et al.
The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device.
PLoS ONE,
2014
, 9 (e89137).
289
Nassini R
et al.
The TRPA1 channel in inflammatory and neuropathic pain and migraine.
Rev. Physiol. Biochem. Pharmacol.,
2014
, 167 (1-43).
290
Fusi C
et al.
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Nat Commun,
2014
, 5 (5736).
291
Fresno N
et al.
Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1.
PLoS ONE,
2014
, 9 (e113841).
292
Zhai C
et al.
Identification of natural compound carnosol as a novel TRPA1 receptor agonist.
Molecules,
2014
, 19 (18733-46).
293
Koh WU
et al.
Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model; an experimental study.
BMC Complement Altern Med,
2014
, 14 (431).
294
Mergler S
et al.
Temperature-sensitive transient receptor potential channels in corneal tissue layers and cells.
Ophthalmic Res.,
2014
, 52 (151-9).
295
Lin YW
et al.
Auricular electroacupuncture reduced inflammation-related epilepsy accompanied by altered TRPA1, pPKCα, pPKCε, and pERk1/2 signaling pathways in kainic acid-treated rats.
Mediators Inflamm.,
2014
, 2014 (493480).
296
297
Mukhopadhyay I
et al.
Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic.
PLoS ONE,
2014
, 9 (e97005).
298
Aubdool AA
et al.
TRPA1 is essential for the vascular response to environmental cold exposure.
Nat Commun,
2014
, 5 (5732).
299
Kiya T
et al.
Establishment of tools for neurogenetic analysis of sexual behavior in the silkmoth, Bombyx mori.
PLoS ONE,
2014
, 9 (e113156).
300
Pezzoli M
et al.
Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices.
Sci Rep,
2014
, 4 (6825).
301
Minett MS
et al.
Significant determinants of mouse pain behaviour.
PLoS ONE,
2014
, 9 (e104458).
302
Kunkler PE
et al.
Intraganglionic signaling as a novel nasal-meningeal pathway for TRPA1-dependent trigeminovascular activation by inhaled environmental irritants.
PLoS ONE,
2014
, 9 (e103086).
303
Eberhardt M
et al.
H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway.
Nat Commun,
2014
, 5 (4381).
304
Bell JT
et al.
Differential methylation of the TRPA1 promoter in pain sensitivity.
Nat Commun,
2014
, 5 (2978).
305
Malmquist J
et al.
Imaging agent of a TRPA1 inhibitor.
J Labelled Comp Radiopharm,
2013 Jul-Aug
, 56 (536-7).
306
Lucaciu OC
et al.
Itch sensation through transient receptor potential channels: a systematic review and relevance to manual therapy.
J Manipulative Physiol Ther,
2013 Jul-Aug
, 36 (385-93).
307
Nishio N
et al.
Reactive oxygen species enhance excitatory synaptic transmission in rat spinal dorsal horn neurons by activating TRPA1 and TRPV1 channels.
Neuroscience,
2013
Sep
5
, 247 (201-12).
308
Mergler S
et al.
Calcium regulation by temperature-sensitive transient receptor potential channels in human uveal melanoma cells.
Cell. Signal.,
2013
Sep
29
, ().
309
Chen J
et al.
Species differences and molecular determinant of TRPA1 cold sensitivity.
Nat Commun,
2013
Sep
27
, 4 (2501).
310
Kamakura T
et al.
Functional expression of TRPV1 and TRPA1 in rat vestibular ganglia.
Neurosci. Lett.,
2013
Sep
27
, 552C (92-97).
311
Kato Y
et al.
Gosha-jinki-gan reduced oxaliplatin-induced hypersensitivity to cold sensation and its effect would be related to suppression of the expression of TRPM8 and TRPA1 in rats.
Anticancer Drugs,
2013
Sep
18
, ().
312
Koivisto A
et al.
TRPA1: A Transducer and Amplifier of Pain and Inflammation.
Basic Clin. Pharmacol. Toxicol.,
2013
Sep
17
, ().
313
Chen J
et al.
Neurological and cellular regulation of visceral hypersensitivity induced by chronic stress and colonic inflammation in rats.
Neuroscience,
2013
Sep
17
, 248 (469-78).
314
Brederson JD
et al.
Targeting TRP channels for pain relief.
Eur. J. Pharmacol.,
2013
Sep
15
, 716 (61-76).
315
Washburn DG
et al.
The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore.
Bioorg. Med. Chem. Lett.,
2013
Sep
1
, 23 (4979-84).
316
Pintér E
et al.
OP24 Characterization of TRPA1-mediated and TRPA1-independent microcirculatory responses to hydrogen sulfide in mice.
Nitric Oxide,
2013
Sep
1
, 31 Suppl 2 (S29-30).
317
Makarieva TN
et al.
Pulchranins B and C, new acyclic guanidine alkaloids from the Far-Eastern marine sponge Monanchora pulchra.
Nat Prod Commun,
2013
Sep
, 8 (1229-32).
318
Pall ML
Two fragrance chemicals may act as toxicants via TRPA1 stimulation rather than via direct mitochondrial action.
Toxicol In Vitro,
2013
Sep
, 27 (2022).
319
Selescu T
et al.
Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin.
Chem. Senses,
2013
Sep
, 38 (563-75).
320
Afroz A
et al.
Gustatory receptor neurons in Manduca sexta contain a TrpA1-dependent signaling pathway that integrates taste and temperature.
Chem. Senses,
2013
Sep
, 38 (605-17).
322
Ortar G
et al.
3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.
Bioorg. Med. Chem. Lett.,
2013
Oct
15
, 23 (5614-8).
323
Wilson SR
et al.
The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch.
Cell,
2013
Oct
10
, 155 (285-95).
324
Hsu CC
et al.
Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2013
Oct
1
, 305 (R769-79).
325
Lin YJ
et al.
Mediator mechanisms involved in TRPV1, TRPA1 and P2X receptor-mediated sensory transduction of pulmonary ROS by vagal lung C-fibers in rats.
Respir Physiol Neurobiol,
2013
Oct
1
, 189 (1-9).
326
Shokoohinia Y
et al.
Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida.
Fitoterapia,
2013
Oct
, 90 (247-51).
327
Maione S
et al.
Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics.
Pharmacol. Res.,
2013
Oct
, 76 (98-105).
328
Takahashi K
et al.
Inflammatory acidic pH enhances hydrogen sulfide-induced transient receptor potential ankyrin 1 activation in RIN-14B cells.
J. Neurosci. Res.,
2013
Oct
, 91 (1322-7).
329
Zhang XY
et al.
Gain-of-function mutations in SCN11A cause familial episodic pain.
Am. J. Hum. Genet.,
2013
Nov
7
, 93 (957-66).
330
Grace MS
et al.
Transient Receptor Potential (TRP) channels in the airway: role in airway disease.
Br. J. Pharmacol.,
2013
Nov
28
, ().
331
Sisignano M
et al.
TRP-channels as key integrators of lipid pathways in nociceptive neurons.
Prog. Lipid Res.,
2013
Nov
25
, 53C (93-107).
332
Patil MJ
et al.
Prolactin regulates TRPV1, TRPA1, and TRPM8 in sensory neurons in a sex-dependent manner: Contribution of prolactin receptor to inflammatory pain.
Am. J. Physiol. Endocrinol. Metab.,
2013
Nov
1
, 305 (E1154-64).
333
Kichko TI
et al.
Bimodal concentration-response of nicotine involves the nicotinic acetylcholine receptor, transient receptor potential vanilloid type 1, and transient receptor potential ankyrin 1 channels in mouse trachea and sensory neurons.
J. Pharmacol. Exp. Ther.,
2013
Nov
, 347 (529-39).
334
Sobhan U
et al.
Immunolocalization and distribution of functional temperature-sensitive TRP channels in salivary glands.
Cell Tissue Res.,
2013
Nov
, 354 (507-19).
335
Nakatsuka K
et al.
Identification of molecular determinants for a potent mammalian TRPA1 antagonist by utilizing species differences.
J. Mol. Neurosci.,
2013
Nov
, 51 (754-62).
336
Acosta MC
et al.
Changes in sensory activity of ocular surface sensory nerves during allergic keratoconjunctivitis.
Pain,
2013
Nov
, 154 (2353-62).
337
Hoffmann T
et al.
TRPA1 and TRPV1 are differentially involved in heat nociception of mice.
Eur J Pain,
2013
Nov
, 17 (1472-82).
338
Krimon S
et al.
P2X3 receptors induced inflammatory nociception modulated by TRPA1, 5-HT3 and 5-HT1A receptors.
Pharmacol. Biochem. Behav.,
2013
Nov
, 112 (49-55).
339
Liu B
et al.
TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis.
FASEB J.,
2013
May
30
, ().
340
Than JY
et al.
Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine.
J. Biol. Chem.,
2013
May
3
, 288 (12818-27).
341
Wilson SR
et al.
The ion channel TRPA1 is required for chronic itch.
J. Neurosci.,
2013
May
29
, 33 (9283-94).
342
Homma Y
et al.
Increased mRNA expression of genes involved in pronociceptive inflammatory reactions in bladder tissue of interstitial cystitis.
J. Urol.,
2013
May
28
, ().
343
Rios ER
et al.
TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
Chem. Biol. Interact.,
2013
May
25
, 203 (573-9).
344
Shapiro D
et al.
Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material.
Chem. Res. Toxicol.,
2013
May
20
, 26 (750-8).
345
Mutoh T
et al.
Desflurane but not sevoflurane augments laryngeal C-fiber inputs to nucleus tractus solitarii neurons by activating transient receptor potential-A1.
Life Sci.,
2013
May
2
, 92 (821-8).
346
Trevisan G
et al.
Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade.
Cancer Res.,
2013
May
15
, 73 (3120-31).
347
Ibarra Y
et al.
Benzoquinone reveals a cysteine-dependent desensitization mechanism of TRPA1.
Mol. Pharmacol.,
2013
May
, 83 (1120-32).
348
Nesuashvili L
et al.
Sensory nerve terminal mitochondrial dysfunction activates airway sensory nerves via transient receptor potential (TRP) channels.
Mol. Pharmacol.,
2013
May
, 83 (1007-19).
349
Ortar G
et al.
Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring.
Eur J Med Chem,
2013
May
, 63 (118-32).
350
Fabrizi L
et al.
Cortical activity evoked by an acute painful tissue-damaging stimulus in healthy adult volunteers.
J. Neurophysiol.,
2013
May
, 109 (2393-403).
351
Romano B
et al.
The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis.
Br. J. Pharmacol.,
2013
May
, 169 (213-29).
352
Schwartz ES
et al.
TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis.
J. Neurosci.,
2013
Mar
27
, 33 (5603-11).
353
Babes A
et al.
The anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel.
Eur. J. Pharmacol.,
2013
Mar
15
, 704 (15-22).
354
Kurohane K
et al.
Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice.
Toxicol. Lett.,
2013
Mar
13
, 217 (192-6).
355
Li C
et al.
Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2013
Mar
1
, 304 (G490-500).
356
Hox V
et al.
Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice.
Am. J. Respir. Crit. Care Med.,
2013
Mar
1
, 187 (486-93).
357
Perin-Martins A
et al.
Mechanisms underlying transient receptor potential ankyrin 1 (TRPA1)-mediated hyperalgesia and edema.
J. Peripher. Nerv. Syst.,
2013
Mar
, 18 (62-74).
358
Wei H
et al.
Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy.
Pharmacol. Biochem. Behav.,
2013
Mar
, 104 (90-6).
359
Liu B
et al.
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain.
Pain,
2013
Jun
29
, ().
360
Verkhratsky A
et al.
TRP Channels Coordinate Ion Signalling in Astroglia.
Rev. Physiol. Biochem. Pharmacol.,
2013
Jun
20
, ().
361
Bellono NW
et al.
UV light phototransduction depolarizes human melanocytes.
Channels (Austin),
2013
Jun
13
, 7 ().
362
Shigetomi E
et al.
TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release.
J. Neurosci.,
2013
Jun
12
, 33 (10143-53).
363
Gees M
et al.
Mechanisms of TRPV1 Activation and Sensitization by Allyl Isothiocyanate.
Mol. Pharmacol.,
2013
Jun
11
, ().
364
Cattaruzza F
et al.
Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2013
Jun
1
, 304 (G1002-12).
365
Kimura Y
et al.
Polysulfides are possible H2S-derived signaling molecules in rat brain.
FASEB J.,
2013
Jun
, 27 (2451-7).
366
Szolcsányi J
et al.
Transient receptor potential vanilloid 1 as a therapeutic target in analgesia.
Expert Opin. Ther. Targets,
2013
Jun
, 17 (641-57).
367
Liu BY
et al.
Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats.
Pulm Pharmacol Ther,
2013
Jun
, 26 (364-72).
368
Tong X
et al.
Genetically encoded calcium indicators and astrocyte calcium microdomains.
Neuroscientist,
2013
Jun
, 19 (274-91).
369
Wei H
et al.
Spinal transient receptor potential ankyrin 1 channel induces mechanical hypersensitivity, increases cutaneous blood flow, and mediates the pronociceptive action of dynorphin A.
J. Physiol. Pharmacol.,
2013
Jun
, 64 (331-40).
370
Park S
et al.
Cold exposure lowers energy expenditure at the cellular level.
Cell Biol. Int.,
2013
Jun
, 37 (638-42).
371
Plevkova J
et al.
The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol.
J. Appl. Physiol.,
2013
Jul
15
, 115 (268-74).
372
Wang S
et al.
TRPA1 ion channels in vagal afferent nerves contribute to ventilator-induced lung injury in a rat model.
Gen. Physiol. Biophys.,
2013
Jul
12
, ().
373
de la Roche J
et al.
The Molecular Basis for Species-specific Activation of Human TRPA1 Protein by Protons Involves Poorly Conserved Residues within Transmembrane Domains 5 and 6.
J. Biol. Chem.,
2013
Jul
12
, 288 (20280-92).
374
Kim S
et al.
Emerging roles of TRPA1 in sensation of oxidative stress and its implications in defense and danger.
Arch. Pharm. Res.,
2013
Jul
, 36 (783-91).
375
Vermeulen W
et al.
Role of TRPV1 and TRPA1 in visceral hypersensitivity to colorectal distension during experimental colitis in rats.
Eur. J. Pharmacol.,
2013
Jan
5
, 698 (404-12).
376
Kondo T
et al.
Activation of p38 MAPK through transient receptor potential A1 in a rat model of gastric distension-induced visceral pain.
Neuroreport,
2013
Jan
23
, 24 (68-72).
377
Tang X
et al.
Temperature integration at the AC thermosensory neurons in Drosophila.
J. Neurosci.,
2013
Jan
16
, 33 (894-901).
378
Ortar G
et al.
Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels.
Bioorg. Med. Chem. Lett.,
2013
Jan
1
, 23 (138-42).
379
Farco JA
et al.
Menthol - pharmacology of an important naturally medicinal "cool".
Mini Rev Med Chem,
2013
Jan
1
, 13 (124-31).
380
Wang H
et al.
Residues in the pore region of Drosophila transient receptor potential A1 dictate sensitivity to thermal stimuli.
J. Physiol. (Lond.),
2013
Jan
1
, 591 (185-201).
381
De Petrocellis L
et al.
2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation.
Expert Opin Ther Pat,
2013
Jan
, 23 (119-47).
382
Wong BW
et al.
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes.
Trends Biochem. Sci.,
2013
Jan
, 38 (3-11).
383
Yang Y
et al.
Wakayama symposium: dependence of corneal epithelial homeostasis on transient receptor potential function.
Ocul Surf,
2013
Jan
, 11 (8-11).
384
Guindon J
et al.
Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following c
Pharmacol. Res.,
2013
Jan
, 67 (94-109).
385
Bellono NW
et al.
UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes.
Proc. Natl. Acad. Sci. U.S.A.,
2013
Feb
5
, 110 (2383-8).
386
de Siqueira RJ
et al.
Linalool-rich Rosewood Oil Induces Vago-vagal Bradycardic and Depressor Reflex in Rats.
Phytother Res,
2013
Feb
27
, ().
387
Klement G
et al.
Characterization of a ligand binding site in the human transient receptor potential ankyrin 1 pore.
Biophys. J.,
2013
Feb
19
, 104 (798-806).
388
Kono T
et al.
Epithelial transient receptor potential ankyrin 1 (TRPA1)-dependent adrenomedullin upregulates blood flow in rat small intestine.
Am. J. Physiol. Gastrointest. Liver Physiol.,
2013
Feb
15
, 304 (G428-36).
389
Xiao R
et al.
A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel.
Cell,
2013
Feb
14
, 152 (806-17).
390
Schaefer EA
et al.
Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells.
Biochem. Pharmacol.,
2013
Feb
1
, 85 (426-38).
391
Nakagawa T
et al.
[Roles of TRPA1 in acute peripheral neuropathy characteristically induced by oxaliplatin].
Nippon Yakurigaku Zasshi,
2013
Feb
, 141 (76-80).
392
Smith PK
et al.
Transient Receptor Potentials (TRPs) and Anaphylaxis.
Curr Allergy Asthma Rep,
2013
Feb
, 13 (93-100).
393
Schulze A
et al.
Apomorphine is a bimodal modulator of TRPA1 channels.
Mol. Pharmacol.,
2013
Feb
, 83 (542-51).
394
White BJ
et al.
Hydrogen sulphide-mediated vasodilatation involves the release of neurotransmitters from sensory nerves in pressurized mesenteric small arteries isolated from rats.
Br. J. Pharmacol.,
2013
Feb
, 168 (785-93).
395
Pereira LM
et al.
Blockade of TRPA1 with HC-030031 attenuates visceral nociception by a mechanism independent of inflammatory resident cells, nitric oxide and the opioid system.
Eur J Pain,
2013
Feb
, 17 (223-33).
396
Qian X
et al.
Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries.
Microcirculation,
2013
Feb
, 20 (138-48).
397
Bonet IJ
et al.
The role of transient receptor potential A 1 (TRPA1) in the development and maintenance of carrageenan-induced hyperalgesia.
Neuropharmacology,
2013
Feb
, 65 (206-12).
398
Büch TR
et al.
Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells.
Chem. Biol. Interact.,
2013
Dec
5
, 206 (462-71).
399
Bassoli A
et al.
Analogues of perillaketone as highly potent agonists of TRPA1 channel.
Food Chem,
2013
Dec
1
, 141 (2044-51).
400
Oh MH
et al.
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
J. Immunol.,
2013
Dec
1
, 191 (5371-82).
401
Wang S
et al.
Etodolac activates and desensitizes transient receptor potential ankyrin 1.
J. Neurosci. Res.,
2013
Dec
, 91 (1591-8).
402
Albarrán L
et al.
Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association.
Biochim. Biophys. Acta,
2013
Dec
, 1833 (3025-34).
403
Tsutsumi T
et al.
The potential role of transient receptor potential type A1 as a mechanoreceptor in human periodontal ligament cells.
Eur. J. Oral Sci.,
2013
Dec
, 121 (538-44).
404
Materazzi S
et al.
Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.
Pain,
2013
Dec
, 154 (2750-8).
405
Diaz-Garcia CM
The TRPA1 channel and oral hypoglycemic agents: Is there complicity in β-cell exhaustion?
Channels (Austin),
2013
Aug
6
, 7 ().
406
Ni L
et al.
A gustatory receptor paralogue controls rapid warmth avoidance in Drosophila.
Nature,
2013
Aug
29
, 500 (580-4).
407
Billeter AT
et al.
Transient Receptor Potential Ion Channels: Powerful Regulators of Cell Function.
Ann. Surg.,
2013
Aug
28
, ().
408
Alpizar YA
et al.
Allyl isothiocyanate sensitizes TRPV1 to heat stimulation.
Pflugers Arch.,
2013
Aug
18
, ().
409
Wei H
et al.
Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat.
Pharmacol. Biochem. Behav.,
2013
Aug
17
, 111C (30-36).
410
Trevisan G
et al.
Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.
Eur. J. Pharmacol.,
2013
Aug
15
, 714 (332-44).
411
O'Mullane LM
et al.
Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium.
J. Urol.,
2013
Aug
, 190 (737-45).
412
Yue HY
et al.
Zingerone enhances glutamatergic spontaneous excitatory transmission by activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa.
J. Neurophysiol.,
2013
Aug
, 110 (658-71).
413
Barthó L
et al.
Purinoceptor-mediated, capsaicin-resistant excitatory effect of allyl isothiocyanate on neurons of the guinea-pig small intestine.
Basic Clin. Pharmacol. Toxicol.,
2013
Aug
, 113 (141-3).
414
Matsushita A
et al.
Inhibition by TRPA1 agonists of compound action potentials in the frog sciatic nerve.
Biochem. Biophys. Res. Commun.,
2013
Apr
26
, 434 (179-84).
415
Meotti FC
et al.
Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis.
Chem. Biol. Interact.,
2013
Apr
25
, 203 (440-7).
416
Nilius B
et al.
Spices: The Savory and Beneficial Science of Pungency.
Rev. Physiol. Biochem. Pharmacol.,
2013
Apr
19
, ().
417
Docherty RJ
et al.
TRPA1 insensitivity of human sural nerve axons after exposure to lidocaine.
Pain,
2013
Apr
18
, ().
418
Lee Y
et al.
Drosophila TRPA1 functions in temperature control of circadian rhythm in pacemaker neurons.
J. Neurosci.,
2013
Apr
17
, 33 (6716-25).
419
Demir IE
et al.
Neural plasticity in the gastrointestinal tract: chronic inflammation, neurotrophic signals, and hypersensitivity.
Acta Neuropathol.,
2013
Apr
, 125 (491-509).
420
Kokel D
et al.
Photochemical activation of TRPA1 channels in neurons and animals.
Nat. Chem. Biol.,
2013
Apr
, 9 (257-63).
421
Fernandes ES
et al.
Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B₄-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1.
FASEB J.,
2013
Apr
, 27 (1664-73).
422
Fariss MW
et al.
Emerging mechanistic targets in lung injury induced by combustion-generated particles.
Toxicol. Sci.,
2013
Apr
, 132 (253-67).
423
Barabas ME
et al.
TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity.
Mol Pain,
2013
, 9 (9).
424
Miura S
et al.
Involvement of TRPA1 activation in acute pain induced by cadmium in mice.
Mol Pain,
2013
, 9 (7).
425
Yu L
et al.
Modulation of TRP channels by resveratrol and other stilbenoids.
Mol Pain,
2013
, 9 (3).
426
Vandewauw I
et al.
Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse.
BMC Neurosci,
2013
, 14 (21).
427
Waszkielewicz AM
et al.
Ion channels as drug targets in central nervous system disorders.
Curr. Med. Chem.,
2013
, 20 (1241-85).
428
Flood TF
et al.
A Large-Scale Behavioral Screen to Identify Neurons Controlling Motor Programs in the Drosophila Brain.
G3 (Bethesda),
2013
, 3 (1629-1637).
429
Mori N
et al.
Intragastric administration of allyl isothiocyanate reduces hyperglycemia in intraperitoneal glucose tolerance test (IPGTT) by enhancing blood glucose consumption in mice.
J. Nutr. Sci. Vitaminol.,
2013
, 59 (56-63).
430
Sałat K
et al.
Transient receptor potential channels - emerging novel drug targets for the treatment of pain.
Curr. Med. Chem.,
2013
, 20 (1409-36).
431
Bautista DM
et al.
TRPA1: A gatekeeper for inflammation.
Annu. Rev. Physiol.,
2013
, 75 (181-200).
432
Nativi C
et al.
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain.
Sci Rep,
2013
, 3 (2005).
433
Andersson DA
et al.
Methylglyoxal evokes pain by stimulating TRPA1.
PLoS ONE,
2013
, 8 (e77986).
434
Yamamoto D
et al.
Insect pheromone behavior: fruit fly.
Methods Mol. Biol.,
2013
, 1068 (261-72).
435
Zhou Y
et al.
Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity.
Nat Commun,
2013
, 4 (2399).
436
Kim MJ
et al.
The TRPA1 agonist, methyl syringate suppresses food intake and gastric emptying.
PLoS ONE,
2013
, 8 (e71603).
437
Benemei S
et al.
TRPA1 and other TRP channels in migraine.
J Headache Pain,
2013
, 14 (71).
438
Liu C
et al.
Molecular characterization of larval peripheral thermosensory responses of the malaria vector mosquito Anopheles gambiae.
PLoS ONE,
2013
, 8 (e72595).
439
Montrucchio DP
et al.
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
PLoS ONE,
2013
, 8 (e67730).
440
Lee Y
Contribution of Drosophila TRPA1-expressing neurons to circadian locomotor activity patterns.
PLoS ONE,
2013
, 8 (e85189).
441
Tsumura M
et al.
Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts.
PLoS ONE,
2013
, 8 (e82233).
442
Lübbert M
et al.
Transient receptor potential channels encode volatile chemicals sensed by rat trigeminal ganglion neurons.
PLoS ONE,
2013
, 8 (e77998).
443
Terada Y
et al.
Contribution of TRPA1 as a downstream signal of proteinase-activated receptor-2 to pancreatic pain.
J. Pharmacol. Sci.,
2013
, 123 (284-7).
444
Yonemitsu T
et al.
TRPA1 detects environmental chemicals and induces avoidance behavior and arousal from sleep.
Sci Rep,
2013
, 3 (3100).
445
Daller JR
et al.
An inexpensive system for evaluating the tussive and anti-tussive properties of chemicals in conscious, unrestrained guinea pigs.
J Pharmacol Toxicol Methods,
2012 Nov-Dec
, 66 (232-7).
446
Chadha A
et al.
Dissection of gain control mechanisms in Drosophila mechanotransduction.
J. Neurosci.,
2012
Sep
19
, 32 (13052-61).
447
Vallin KS
et al.
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor.
Bioorg. Med. Chem. Lett.,
2012
Sep
1
, 22 (5485-92).
448
[Thermosensitive TRP channels gene expression in hypothalamus of normal rats and rats adapted to cold].
Ross Fiziol Zh Im I M Sechenova,
2012
Sep
, 98 (1101-10).
449
Ferrer-Montiel A
et al.
Advances in modulating thermosensory TRP channels.
Expert Opin Ther Pat,
2012
Sep
, 22 (999-1017).
450
Edelmayer RM
et al.
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain.
Pain,
2012
Sep
, 153 (1949-58).
452
Gyekis JP
et al.
Gustatory, trigeminal, and olfactory aspects of nicotine intake in three mouse strains.
Behav. Genet.,
2012
Sep
, 42 (820-9).
453
Vetter I
et al.
Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.
EMBO J.,
2012
Oct
3
, 31 (3795-808).
454
Klafke JZ
et al.
Involvement of the glutamatergic system in the nociception induced intrathecally for a TRPA1 agonist in rats.
Neuroscience,
2012
Oct
11
, 222 (136-46).
455
Keene AC
et al.
Optogenetic induction of aversive taste memory.
Neuroscience,
2012
Oct
11
, 222 (173-80).
456
Grace M
et al.
Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin.
Thorax,
2012
Oct
, 67 (891-900).
457
Patwardhan A
et al.
Receptor specificity defines algogenic properties of propofol and fospropofol.
Anesth. Analg.,
2012
Oct
, 115 (837-40).
458
Jang Y
et al.
Quantitative analysis of TRP channel genes in mouse organs.
Arch. Pharm. Res.,
2012
Oct
, 35 (1823-30).
459
Lee SM
et al.
An ultrastructural evidence for the expression of transient receptor potential ankyrin 1 (TRPA1) in astrocytes in the rat trigeminal caudal nucleus.
J. Chem. Neuroanat.,
2012
Oct
, 45 (45-9).
460
Wang Y
et al.
Menthol inhibits the proliferation and motility of prostate cancer DU145 cells.
Pathol. Oncol. Res.,
2012
Oct
, 18 (903-10).
461
Winston JH
et al.
Developmental Origins of Functional Dyspepsia-Like Gastric Hypersensitivity in Rats.
Gastroenterology,
2012
Nov
8
, ().
462
Shiba T
et al.
Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model.
Toxicol. Appl. Pharmacol.,
2012
Nov
1
, 264 (370-6).
463
Nilius B
et al.
The transient receptor potential channel TRPA1: from gene to pathophysiology.
Pflugers Arch.,
2012
Nov
, 464 (425-58).
464
Chianese G
et al.
Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels.
Mar Drugs,
2012
Nov
, 10 (2435-47).
465
Knaapila A
et al.
Genetic analysis of chemosensory traits in human twins.
Chem. Senses,
2012
Nov
, 37 (869-81).
466
Uchida K
et al.
Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel.
Chem. Senses,
2012
Nov
, 37 (809-18).
467
Son HJ
et al.
Activation of the Chemosensory Ion Channels TRPA1 and TRPV1 by Hydroalcohol Extract of Kalopanax pictus Leaves.
Biomol Ther (Seoul),
2012
Nov
, 20 (550-5).
468
Stavermann M
et al.
Temperature-dependent calcium-induced calcium release via InsP(3) receptors in mouse olfactory ensheathing glial cells.
,
2012
May
25
, ().
469
Sura L
et al.
C-terminal acidic cluster is involved in Ca2+-induced regulation of human transient receptor potential ankyrin 1 channel.
J. Biol. Chem.,
2012
May
25
, 287 (18067-77).
470
Ortar G
et al.
Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds.
Bioorg. Med. Chem. Lett.,
2012
May
15
, 22 (3535-9).
471
472
Bianchi BR
et al.
Species comparison and pharmacological characterization of human, monkey, rat, and mouse TRPA1 channels.
J. Pharmacol. Exp. Ther.,
2012
May
, 341 (360-8).
473
Fernandes ES
et al.
The functions of TRPA1 and TRPV1: moving away from sensory nerves.
Br. J. Pharmacol.,
2012
May
, 166 (510-21).
474
Wang S
et al.
Warmth suppresses and desensitizes damage-sensing ion channel TRPA1.
,
2012
Mar
29
, 8 (22).
475
Baraldi PG
et al.
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Bioorg. Med. Chem.,
2012
Mar
1
, 20 (1690-8).
476
Kanezaki M
et al.
Effect of cigarette smoking on cough reflex induced by TRPV1 and TRPA1 stimulations.
Respir Med,
2012
Mar
, 106 (406-12).
477
Nakamura Y
et al.
Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons.
J. Neurochem.,
2012
Mar
, 120 (1036-47).
478
Barrière DA
et al.
Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization.
Pain,
2012
Mar
, 153 (553-61).
479
Capasso R
et al.
Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects.
Br. J. Pharmacol.,
2012
Mar
, 165 (1966-77).
480
Shintaku K
et al.
Activation of transient receptor potential A1 by a non-pungent capsaicin-like compound, capsiate.
Br. J. Pharmacol.,
2012
Mar
, 165 (1476-86).
481
Preti D
et al.
TRP channels as therapeutic targets in airway disorders: a patent review.
Expert Opin Ther Pat,
2012
Jun
, 22 (663-95).
482
Oehler B
et al.
TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde.
Naunyn Schmiedebergs Arch. Pharmacol.,
2012
Jun
, 385 (555-63).
483
Izzo AA
et al.
Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice.
Br. J. Pharmacol.,
2012
Jun
, 166 (1444-60).
484
Bennett SM
et al.
Differences in the chemesthetic subqualities of capsaicin, ibuprofen, and olive oil.
Chem. Senses,
2012
Jun
, 37 (471-8).
485
Teichert RW
et al.
Characterization of two neuronal subclasses through constellation pharmacology.
,
2012
Jul
9
, ().
486
Zayats V
et al.
Regulation of the transient receptor potential channel TRPA1 by its N-terminal ankyrin repeat domain.
,
2012
Jul
3
, ().
487
Hatano N
et al.
HIF1α switches on TRPA1 gene expression via a hypoxia response element-like motif to modulate cytokine release.
,
2012
Jul
26
, ().
488
Okubo K
et al.
Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.
Br. J. Pharmacol.,
2012
Jul
, 166 (1738-43).
489
Kang K
et al.
Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila.
Nature,
2012
Jan
5
, 481 (76-80).
490
Laub KR
et al.
Comparing ion conductance recordings of synthetic lipid bilayers with cell membranes containing TRP channels.
,
2012
Jan
28
, ().
491
Zhong L
et al.
Thermosensory and non-thermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat sensor domains of a thermoTRP channel.
Cell Rep,
2012
Jan
26
, 1 (43-55).
492
Gijsen HJ
et al.
Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists.
Bioorg. Med. Chem. Lett.,
2012
Jan
15
, 22 (797-800).
493
Bang S
et al.
Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.
Neurosci. Lett.,
2012
Jan
11
, 506 (297-302).
494
Braun AP
Structural remodeling of the N-terminus tunes TRPA1 channel activation and regulates behavioral responses in Drosophila.
,
2012
Jan
1
, 6 ().
495
Shigetomi E
et al.
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3.
Nat. Neurosci.,
2012
Jan
, 15 (70-80).
496
Raemdonck K
et al.
A role for sensory nerves in the late asthmatic response.
Thorax,
2012
Jan
, 67 (19-25).
497
Mergler S
et al.
Altered calcium regulation by thermosensitive transient receptor potential channels in etoposide-resistant WERI-Rb1 retinoblastoma cells.
Exp. Eye Res.,
2012
Jan
, 94 (157-73).
498
Glendinning JI
et al.
Fetal ethanol exposure attenuates aversive oral effects of TrpV1, but not TrpA1 agonists in rats.
,
2012
Feb
29
, ().
499
500
Morera E
et al.
Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.
Bioorg. Med. Chem. Lett.,
2012
Feb
15
, 22 (1674-7).
501
Pan YA
et al.
Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons.
Development,
2012
Feb
, 139 (591-600).
502
Nassini R
et al.
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.
Brain,
2012
Feb
, 135 (376-90).
503
Koivisto A
Sustained TRPA1 activation in vivo.
Acta Physiol (Oxf),
2012
Feb
, 204 (248-54).
504
Hirata H
et al.
Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels.
J. Neurophysiol.,
2012
Feb
, 107 (1199-209).
505
Kurogi M
et al.
Green tea polyphenol epigallocatechin gallate activates TRPA1 in an intestinal enteroendocrine cell line, STC-1.
Chem. Senses,
2012
Feb
, 37 (167-77).
506
Hatano N
et al.
Stimulation of human TRPA1 channels by clinical concentrations of the anti-rheumatic drug, auranofin.
Am. J. Physiol., Cell Physiol.,
2012
Dec
5
, ().
507
Alpizar YA
et al.
Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1.
Pflugers Arch.,
2012
Dec
28
, ().
508
Son HJ
et al.
Methyl syringate, a low-molecular-weight phenolic ester, as an activator of the chemosensory ion channel TRPA1.
Arch. Pharm. Res.,
2012
Dec
, 35 (2211-8).
509
Shen MY
et al.
Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2012
Dec
, 303 (R1175-85).
510
De Petrocellis L
et al.
A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons.
Br. J. Pharmacol.,
2012
Dec
, 167 (1643-51).
511
McClenaghan C
et al.
TRPA1 agonist activity of probenecid desensitizes channel responses: consequences for screening.
Assay Drug Dev Technol,
2012
Dec
, 10 (533-41).
512
Saito S
et al.
Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates.
J. Biol. Chem.,
2012
Aug
31
, 287 (30743-54).
513
Ogawa H
et al.
H(2)S functions as a nociceptive messenger through transient receptor potential ankyrin 1 (TRPA1) activation.
Neuroscience,
2012
Aug
30
, 218 (335-43).
514
May D
et al.
Differential expression and functionality of TRPA1 protein genetic variants in conditions of thermal stimulation.
J. Biol. Chem.,
2012
Aug
3
, 287 (27087-94).
515
Dong HW
et al.
Expression of transient receptor potential (TRP) channel mRNAs in the mouse olfactory bulb.
Neurosci. Lett.,
2012
Aug
22
, 524 (49-54).
516
Eberhardt MJ
et al.
Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies.
J. Biol. Chem.,
2012
Aug
17
, 287 (28291-306).
517
Pozsgai G
et al.
The role of transient receptor potential ankyrin 1 (TRPA1) receptor activation in hydrogen-sulphide-induced CGRP-release and vasodilation.
Eur. J. Pharmacol.,
2012
Aug
15
, 689 (56-64).
518
Brozmanova M
et al.
Comparison of TRPA1-versus TRPV1-mediated cough in guinea pigs.
Eur. J. Pharmacol.,
2012
Aug
15
, 689 (211-8).
520
Cho JH
et al.
TRPA1-like channels enhance glycinergic transmission in medullary dorsal horn neurons.
J. Neurochem.,
2012
Aug
, 122 (691-701).
521
Kim YS
et al.
Expression of transient receptor potential ankyrin 1 in human dental pulp.
J Endod,
2012
Aug
, 38 (1087-92).
522
Gregus AM
et al.
Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.
Proc. Natl. Acad. Sci. U.S.A.,
2012
Apr
24
, 109 (6721-6).
523
Bharate SS
et al.
Modulation of thermoreceptor TRPM8 by cooling compounds.
ACS Chem Neurosci,
2012
Apr
18
, 3 (248-67).
524
Koseki J
et al.
Role of transient receptor potential ankyrin 1 in gastric accommodation in conscious guinea pigs.
J. Pharmacol. Exp. Ther.,
2012
Apr
, 341 (205-12).
525
Materazzi S
et al.
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.
Pflugers Arch.,
2012
Apr
, 463 (561-9).
526
Komatsu T
et al.
Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner.
Pflugers Arch.,
2012
Apr
, 463 (549-59).
527
Liu T
et al.
Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice.
Neurosci Bull,
2012
Apr
, 28 (145-54).
528
Okun A
et al.
Afferent drive elicits ongoing pain in a model of advanced osteoarthritis.
Pain,
2012
Apr
, 153 (924-33).
529
Moilanen LJ
et al.
TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse.
Sci Rep,
2012
, 2 (380).
530
Cao DS
et al.
Expression of Transient Receptor Potential Ankyrin 1 (TRPA1) and Its Role in Insulin Release from Rat Pancreatic Beta Cells.
PLoS ONE,
2012
, 7 (e38005).
531
Numazawa S
et al.
Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells.
Biol. Pharm. Bull.,
2012
, 35 (346-54).
532
Smit LA
et al.
Transient receptor potential genes, smoking, occupational exposures and cough in adults.
Respir. Res.,
2012
, 13 (26).
533
Barabas ME
et al.
TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons.
PLoS ONE,
2012
, 7 (e47988).
534
Weng Y
et al.
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception.
Mol Pain,
2012
, 8 (75).
535
Ohkawara S
et al.
Methylglyoxal activates the human transient receptor potential ankyrin 1 channel.
J Toxicol Sci,
2012
, 37 (831-5).
536
Inoue N
et al.
Etodolac blocks the allyl isothiocyanate-induced response in mouse sensory neurons by selective TRPA1 activation.
Pharmacology,
2012
, 90 (47-54).
537
Motter AL
et al.
TRPA1 is a polyunsaturated fatty acid sensor in mammals.
PLoS ONE,
2012
, 7 (e38439).
538
Lennertz RC
et al.
TRPA1 mediates mechanical sensitization in nociceptors during inflammation.
PLoS ONE,
2012
, 7 (e43597).
539
Tsubota-Matsunami M
et al.
Colonic hydrogen sulfide-induced visceral pain and referred hyperalgesia involve activation of both Ca(v)3.2 and TRPA1 channels in mice.
J. Pharmacol. Sci.,
2012
, 119 (293-6).
540
Takaishi M
et al.
1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1.
Mol Pain,
2012
, 8 (86).
541
Hata T
et al.
Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels.
PLoS ONE,
2012
, 7 (e48072).
542
Andersson DA
et al.
TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.
PLoS ONE,
2012
, 7 (e46917).
543
Donnerer J
et al.
Thermal stimulation of primary sensory neurons in the rat hind paw: effect of morphine on ERK1/2 phosphorylation, TRPV1 and TRPA1 channel expression.
Pharmacology,
2012
, 90 (298-306).
544
Tamura Y
et al.
Ingestion of cinnamaldehyde, a TRPA1 agonist, reduces visceral fats in mice fed a high-fat and high-sucrose diet.
J. Nutr. Sci. Vitaminol.,
2012
, 58 (9-13).
545
Sample SJ
et al.
Functional adaptation in female rats: the role of estrogen signaling.
PLoS ONE,
2012
, 7 (e43215).
546
Huang D
et al.
Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura.
Mol Pain,
2012
, 8 (66).
547
Nassini R
et al.
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
PLoS ONE,
2012
, 7 (e42454).
548
Zhao M
et al.
Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice.
Mol Pain,
2012
, 8 (55).
549
Lapointe TK
et al.
The role of TRPA1 in visceral inflammation and pain.
Channels (Austin),
2011 Nov-Dec
, 5 (525-9).
550
Willis DN
et al.
Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants.
,
2011
Sep
8
, ().
551
Miller M
et al.
Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
J. Biol. Chem.,
2011
Sep
23
, 286 (33436-46).
552
Hillery CA
et al.
Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease.
Blood,
2011
Sep
22
, 118 (3376-83).
553
Bodkin JV
et al.
Transient receptor potential ankyrin 1: emerging pharmacology and indications for cardiovascular biology.
Acta Physiol (Oxf),
2011
Sep
, 203 (87-98).
554
Ye Y
et al.
Nerve growth factor links oral cancer progression, pain, and cachexia.
Mol. Cancer Ther.,
2011
Sep
, 10 (1667-76).
555
Patil M
et al.
Cannabinoid receptor antagonists AM251 and AM630 activate TRPA1 in sensory neurons.
Neuropharmacology,
2011
Sep
, 61 (778-88).
556
Park CK
et al.
Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.
J. Neurosci.,
2011
Oct
19
, 31 (15072-85).
557
Chen Y
et al.
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
Neuroscience,
2011
Oct
13
, 193 (440-51).
558
Belvisi MG
et al.
Transient receptor potential A1 channels: insights into cough and airway inflammatory disease.
Chest,
2011
Oct
, 140 (1040-7).
559
Takahashi N
et al.
TRPA1 underlies a sensing mechanism for O2.
Nat. Chem. Biol.,
2011
Oct
, 7 (701-11).
560
Engel MA
et al.
TRPA1 and substance P mediate colitis in mice.
Gastroenterology,
2011
Oct
, 141 (1346-58).
561
Keh SM
et al.
The menthol and cold sensation receptor TRPM8 in normal human nasal mucosa and rhinitis.
Rhinology,
2011
Oct
, 49 (453-7).
562
Brozmanova M
et al.
Preferential activation of the vagal nodose nociceptive subtype by TRPA1 agonists in the guinea pig esophagus.
Neurogastroenterol. Motil.,
2011
Oct
, 23 (e437-45).
563
Mukhopadhyay I
et al.
Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.
J. Recept. Signal Transduct. Res.,
2011
Oct
, 31 (350-8).
564
Garrison SR
et al.
The dynamic TRPA1 channel: a suitable pharmacological pain target?
Curr Pharm Biotechnol,
2011
Oct
, 12 (1689-97).
565
Cvetkov TL
et al.
Molecular Architecture and Subunit Organization of TRPA1 Ion Channel Revealed by Electron Microscopy.
J. Biol. Chem.,
2011
Nov
4
, 286 (38168-76).
566
568
Cordero-Morales JF
et al.
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.
Proc. Natl. Acad. Sci. U.S.A.,
2011
Nov
15
, 108 (E1184-91).
570
Alenmyr L
et al.
TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
Clin Physiol Funct Imaging,
2011
Nov
, 31 (435-44).
571
Artim DE
et al.
Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder.
Exp. Neurol.,
2011
Nov
, 232 (90-9).
572
Byers MR
et al.
Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels.
Arch. Oral Biol.,
2011
Nov
, 56 (1199-220).
573
Horváth G
et al.
Lutein Inhibits the Function of the Transient Receptor Potential A1 Ion Channel in Different In Vitro and In Vivo Models.
,
2011
May
4
, ().
574
Poole DP
et al.
Transient Receptor Potential Ankyrin 1 is Expressed by Inhibitory Motoneurons of the Mouse Intestine.
,
2011
May
4
, ().
575
Pertovaara A
et al.
TRPA1 ion channel in the spinal dorsal horn as a therapeutic target in central pain hypersensitivity and cutaneous neurogenic inflammation.
,
2011
May
27
, ().
576
Wang YY
et al.
A TRPA1-dependent mechanism for the pungent sensation of weak acids.
,
2011
May
16
, ().
577
Xiao B
et al.
Scratching the surface: a role of pain-sensing TRPA1 in itch.
Nat. Neurosci.,
2011
May
, 14 (540-2).
578
Wilson SR
et al.
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Nat. Neurosci.,
2011
May
, 14 (595-602).
579
Andrade EL
et al.
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Am. J. Physiol. Renal Physiol.,
2011
May
, 300 (F1223-34).
580
Zhang H
et al.
Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons.
Anesthesiology,
2011
May
, 114 (1169-79).
581
Jiang LH
et al.
Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.
Curr Drug Targets,
2011
May
, 12 (724-36).
582
Koch M
et al.
The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels.
Hippocampus,
2011
May
, 21 (554-64).
583
Kaji I
et al.
Effects of luminal thymol on epithelial transport in human and rat colon.
,
2011
Mar
3
, ().
584
Yokoyama T
et al.
Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats.
Eur. J. Pharmacol.,
2011
Mar
25
, 655 (31-7).
585
Banke TG
The dilated TRPA1 channel pore state is blocked by amiloride and analogues.
Brain Res.,
2011
Mar
24
, 1381 (21-30).
586
Zhang Y
et al.
Modulation of Transient Receptor Potential (TRP) Channels by Chinese Herbal Extracts.
,
2011
Mar
23
, ().
587
Terada Y
et al.
Specific hydroxy fatty acids in royal jelly activate TRPA1.
J. Agric. Food Chem.,
2011
Mar
23
, 59 (2627-35).
588
Holzer P
Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
,
2011
Mar
17
, ().
589
Banner KH
et al.
TRP channels: Emerging targets for respiratory disease.
,
2011
Mar
17
, ().
590
Franck MC
et al.
Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse.
,
2011
Mar
14
, ().
591
Chen J
et al.
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.
,
2011
Mar
12
, ().
592
Mahoney JL
et al.
Evidence for involvement of TRPA1 in the detection of vibrations by hair bundle mechanoreceptors in sea anemones.
,
2011
Mar
11
, ().
593
Shen WL
et al.
Function of rhodopsin in temperature discrimination in Drosophila.
Science,
2011
Mar
11
, 331 (1333-6).
595
Fernandes ES
et al.
A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis.
Arthritis Rheum.,
2011
Mar
, 63 (819-29).
596
Raisinghani M
et al.
Activation Characteristics of Transient Receptor Potential Ankyrin 1 and its Role in Nociception.
,
2011
Jun
8
, ().
597
Donlea JM
et al.
Inducing sleep by remote control facilitates memory consolidation in Drosophila.
Science,
2011
Jun
24
, 332 (1571-6).
598
Ryckmans T
et al.
Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.
,
2011
Jun
21
, ().
599
Silva CR
et al.
The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice.
Life Sci.,
2011
Jun
20
, 88 (1077-87).
600
Deering-Rice CE
et al.
Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP.
Chem. Res. Toxicol.,
2011
Jun
20
, 24 (950-9).
601
Eid SR
Therapeutic Targeting of TRP Channels - The TR(i)P to Pain Relief.
,
2011
Jun
14
, ().
603
Garrity PA
Weakly acidic, but strongly irritating: TRPA1 and the activation of nociceptors by cytoplasmic acidification.
J. Gen. Physiol.,
2011
Jun
, 137 (489-91).
604
Mori N
et al.
Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice.
Am. J. Physiol. Regul. Integr. Comp. Physiol.,
2011
Jun
, 300 (R1494-505).
605
Patil MJ
et al.
Chronic alteration in phosphatidylinositol 4,5-biphosphate levels regulates capsaicin and mustard oil responses.
J. Neurosci. Res.,
2011
Jun
, 89 (945-54).
606
Juszczak K
et al.
Effect of partial and complete blockade of vanilloid (TRPV1-6) and ankyrin (TRPA1) transient receptor potential ion channels on urinary bladder motor activity in an experimental hyperosmolar overactive bladder rat model.
J. Physiol. Pharmacol.,
2011
Jun
, 62 (321-6).
607
Vay L
et al.
The thermo-TRP ion channel family: properties and therapeutic implications.
,
2011
Jul
28
, ().
608
Malin S
et al.
TRPV1 and TRPA1 Function and Modulation Are Target Tissue Dependent.
J. Neurosci.,
2011
Jul
20
, 31 (10516-28).
609
Miyamoto R
et al.
Time- and concentration-dependent activation of TRPA1 by hydrogen sulfide in rat DRG neurons.
Neurosci. Lett.,
2011
Jul
20
, 499 (137-42).
610
Brierley SM
et al.
TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.
J. Physiol. (Lond.),
2011
Jul
15
, 589 (3575-93).
611
Roberts K
et al.
A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde.
J Clin Neurosci,
2011
Jul
, 18 (926-32).
612
Nassini R
et al.
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.
Pain,
2011
Jul
, 152 (1621-31).
613
Ruparel NB
et al.
Desensitization of transient receptor potential ankyrin 1 (TRPA1) by the TRP vanilloid 1-selective cannabinoid arachidonoyl-2 chloroethanolamine.
Mol. Pharmacol.,
2011
Jul
, 80 (117-23).
614
Hazari MS
et al.
TRPA1 and sympathetic activation contribute to increased risk of triggered cardiac arrhythmias in hypertensive rats exposed to diesel exhaust.
Environ. Health Perspect.,
2011
Jul
, 119 (951-7).
615
Peyrot des Gachons C
et al.
Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal.
J. Neurosci.,
2011
Jan
19
, 31 (999-1009).
616
Holzer P
TRP channels in the digestive system.
Curr Pharm Biotechnol,
2011
Jan
1
, 12 (24-34).
617
Akopian AN
Regulation of nociceptive transmission at the periphery via TRPA1-TRPV1 interactions.
Curr Pharm Biotechnol,
2011
Jan
1
, 12 (89-94).
618
Yokoyama S
et al.
Molecular convergence of infrared vision in snakes.
Mol. Biol. Evol.,
2011
Jan
, 28 (45-8).
619
Sadofsky LR
et al.
TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids.
Pharmacol. Res.,
2011
Jan
, 63 (30-6).
620
Bang S
et al.
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
,
2011
Feb
23
, ().
621
Maione S
et al.
Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action.
Br. J. Pharmacol.,
2011
Feb
, 162 (584-96).
622
Earley S
Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels.
J. Cardiovasc. Pharmacol.,
2011
Feb
, 57 (148-53).
623
Deering-Rice CE
et al.
Transient Receptor Potential Vanilloid-1 (TRPV1) Is a Mediator of Lung Toxicity for Coal Fly Ash Particulate Material.
,
2011
Dec
9
, ().
624
Wang L
et al.
Identification of in vivo disulfide conformation of the TRPA1 ion channel.
,
2011
Dec
29
, ().
625
Kaji I
et al.
Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon.
,
2011
Dec
29
, ().
626
Park CK
et al.
Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1.
J. Neurosci.,
2011
Dec
14
, 31 (18433-8).
627
Brain SD
TRPV1 and TRPA1 channels in inflammatory pain: elucidating mechanisms.
Ann. N. Y. Acad. Sci.,
2011
Dec
, 1245 (36-7).
628
Zhong J
et al.
Umbellulone modulates TRP channels.
Pflugers Arch.,
2011
Dec
, 462 (861-70).
629
Zhong J
et al.
Ligustilide: a novel TRPA1 modulator.
Pflugers Arch.,
2011
Dec
, 462 (841-9).
630
Weller K
et al.
TRPV1, TRPA1, and CB1 in the isolated vagus nerve - Axonal chemosensitivity and control of neuropeptide release.
Neuropeptides,
2011
Dec
, 45 (391-400).
631
Aubdool AA
et al.
Neurovascular aspects of skin neurogenic inflammation.
J. Investig. Dermatol. Symp. Proc.,
2011
Dec
, 15 (33-9).
632
Stepanyan RS
et al.
TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.
J. Assoc. Res. Otolaryngol.,
2011
Dec
, 12 (729-40).
633
Haas ET
et al.
Tooth injury increases expression of the cold sensitive TRP channel TRPA1 in trigeminal neurons.
Arch. Oral Biol.,
2011
Dec
, 56 (1604-9).
634
Jain A
et al.
TRP-channel-specific cutaneous eicosanoid release patterns.
Pain,
2011
Dec
, 152 (2765-72).
635
Uhl GR
et al.
Menthol preference among smokers: association with TRPA1 variants.
Nicotine Tob. Res.,
2011
Dec
, 13 (1311-5).
636
Gracheva EO
et al.
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats.
Nature,
2011
Aug
4
, 476 (88-91).
637
Frasnelli J
et al.
Perception of specific trigeminal chemosensory agonists.
Neuroscience,
2011
Aug
25
, 189 (377-83).
638
Zhou Y
et al.
Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.
Respir Physiol Neurobiol,
2011
Aug
15
, 177 (327-32).
639
Leamy AW
et al.
Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1.
,
2011
Aug
10
, ().
640
Tóth DM
et al.
Nociception, neurogenic inflammation and thermoregulation in TRPV1 knockdown transgenic mice.
Cell. Mol. Life Sci.,
2011
Aug
, 68 (2589-601).
641
De Petrocellis L
et al.
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.
Br. J. Pharmacol.,
2011
Aug
, 163 (1479-94).
642
Choi MJ
et al.
Transient receptor potential (TRP) A1 activated currents in TRPV1 and cholecystokinin-sensitive cranial visceral afferent neurons.
Brain Res.,
2011
Apr
6
, 1383 (36-42).
643
644
Harrington AM
et al.
A novel role for TRPM8 in visceral afferent function.
,
2011
Apr
11
, ().
645
Nilius B
et al.
Irritating channels: the case of TRPA1.
J. Physiol. (Lond.),
2011
Apr
1
, 589 (1543-9).
646
Graepel R
et al.
4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo.
J. Pharmacol. Exp. Ther.,
2011
Apr
, 337 (117-24).
647
Bobkov YV
et al.
The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings.
Biochim. Biophys. Acta,
2011
Apr
, 1808 (1120-8).
648
Schwartz ES
et al.
Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation.
Gastroenterology,
2011
Apr
, 140 (1283-1291.e1-2).
649
El Karim IA
et al.
Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.
J Endod,
2011
Apr
, 37 (473-8).
650
Wetsel WC
Sensing hot and cold with TRP channels.
Int J Hyperthermia,
2011
, 27 (388-98).
651
Chung MK
et al.
Role of TRP channels in pain sensation.
Adv. Exp. Med. Biol.,
2011
, 704 (615-36).
652
Harteneck C
et al.
Synthetic modulators of TRP channel activity.
Adv. Exp. Med. Biol.,
2011
, 704 (87-106).
653
Knowlton WM
et al.
Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.
PLoS ONE,
2011
, 6 (e25894).
654
Skryma R
et al.
From urgency to frequency: facts and controversies of TRPs in the lower urinary tract.
Nat Rev Urol,
2011
, 8 (617-30).
655
Luo J
et al.
Cell-based calcium assay for medium to high throughput screening of TRP channel functions using FlexStation 3.
J Vis Exp,
2011
, ().
656
Bae YC
et al.
Ultrastructural basis for craniofacial sensory processing in the brainstem.
Int. Rev. Neurobiol.,
2011
, 97 (99-141).
657
Yoshida N
et al.
Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin.
Mol Pain,
2011
, 7 (41).
658
Geng J
et al.
Molecular Evolution of the Infrared Sensory Gene TRPA1 in Snakes and Implications for Functional Studies.
PLoS ONE,
2011
, 6 (e28644).
659
Leffler A
et al.
Activation of TRPA1 by membrane permeable local anesthetics.
Mol Pain,
2011
, 7 (62).
660
Neely GG
et al.
TrpA1 regulates thermal nociception in Drosophila.
PLoS ONE,
2011
, 6 (e24343).
661
Andersson DA
et al.
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
Nat Commun,
2011
, 2 (551).
662
Brenneis C
et al.
Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation.
Mol Pain,
2011
, 7 (78).
663
Nieto-Posadas A
et al.
TRP channel gating physiology.
Curr Top Med Chem,
2011
, 11 (2131-50).
664
Strassmaier T
et al.
Transient receptor potential A1 modulators.
Curr Top Med Chem,
2011
, 11 (2227-36).
665
Juszczak K
et al.
[Capsaicin and lidocaine usage in functional disorders of urinary bladder].
Folia Med Cracov,
2011
, 51 (91-8).
666
Vay L
et al.
Current perspectives on the modulation of thermo-TRP channels: new advances and therapeutic implications.
Expert Rev Clin Pharmacol,
2010
Sep
, 3 (687-704).
667
Takeda M
et al.
Sensor Mechanism and Afferent Signal Transduction of the Urinary Bladder: Special Focus on transient receptor potential Ion Channels.
Low Urin Tract Symptoms,
2010
Sep
, 2 (51-60).
668
Rech JC
et al.
Recent advances in the biology and medicinal chemistry of TRPA1.
Future Med Chem,
2010
May
, 2 (843-58).
669
Berni J
et al.
Using Neurogenetics and the Warmth-Gated Ion Channel TRPA1 to Study the Neural Basis of Behavior in Drosophila.
J Undergrad Neurosci Educ,
2010
Fall
, 9 (A5-A14).
670
Patil MJ
et al.
Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+.
Neuroscience,
2010
Dec
29
, 171 (1109-19).
671
Nagatomo K
et al.
The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression.
Biophys. J.,
2010
Dec
1
, 99 (3609-18).
672
Dong Y
et al.
Transient receptor potential A1 is involved in cold-induced contraction in the isolated rat colon smooth muscle.
Sheng Li Xue Bao,
2010
Aug
25
, 62 (349-56).
673
Ai Y
et al.
Molecular modeling studies on 11H-dibenz[b,e]azepine and dibenz[b,f][1,4]oxazepine derivatives as potent agonists of the human TRPA1 receptor.
Molecules,
2010
, 15 (9364-79).
674
Anand U
et al.
Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.
Mol Pain,
2010
, 6 (82).
675
Takumida M
et al.
Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear.
Acta Otolaryngol.,
2009
Oct
, 129 (1050-60).