SK2

1

Yu CC et al. Arrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium current.
Heart Rhythm, 2016 May 7 , ().

2

Berthe W et al. New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors.
ChemMedChem, 2016 Jun 9 , ().

3

Kanju P et al. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.
Sci Rep, 2016 , 6 (26894).

4

Ye F et al. The Scorpion Toxin Analogue BmKTX-D33H as a Potential Kv1.3 Channel-Selective Immunomodulator for Autoimmune Diseases.
Toxins (Basel), 2016 , 8 ().

5

Bragança B et al. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria.
Front Pharmacol, 2016 , 7 (45).

6

Mizukami K et al. Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats.
Am. J. Physiol. Heart Circ. Physiol., 2015 Sep 15 , 309 (H1066-74).

7

Schulte-Mecklenbeck A et al. The two-pore domain K2 P channel TASK2 drives human NK-cell proliferation and cytolytic function.
Eur. J. Immunol., 2015 Sep , 45 (2602-14).

8

Parajuli N et al. Determinants of ventricular arrhythmias in human explanted hearts with dilated cardiomyopathy.
Eur. J. Clin. Invest., 2015 Oct 7 , ().

9

Hurd L et al. A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia.
Am. J. Med. Genet. A, 2015 Oct , 167A (2286-93).

10

Dobbins R et al. GSK256073 acutely regulates NEFA levels via HCA2 agonism but does not achieve durable glycaemic control in type 2 diabetes. A randomised trial.
Eur. J. Pharmacol., 2015 May 15 , 755 (95-101).

11

Hancock JM et al. Selective activation of heteromeric SK channels contributes to action potential repolarization in mouse atrial myocytes.
Heart Rhythm, 2015 May , 12 (1003-15).

12

Ehling P et al. The CNS under pathophysiologic attack--examining the role of K₂p channels.
Pflugers Arch., 2015 May , 467 (959-72).

13

Yi F et al. Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria.
J. Biol. Chem., 2015 Mar 13 , 290 (7016-26).

14

Deng Y et al. Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice.
Eur. J. Pharmacol., 2015 Mar 11 , ().

15

Iosub R et al. Calcium-Induced calcium release during action potential firing in developing inner hair cells.
Biophys. J., 2015 Mar 10 , 108 (1003-12).

16

Sprecher D et al. Discovery and characterization of GSK256073, a non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) agonist.
Eur. J. Pharmacol., 2015 Jun 5 , 756 (1-7).

17

Karppinen S et al. Ca(2+) -activated K(+) current is essential for maintaining excitability and gene transcription in early embryonic cardiomyocytes.
Acta Physiol (Oxf), 2015 Jun 12 , ().

18

Lizarraga SB et al. Uncovering a Role for SK2 in Angelman Syndrome.
Cell Rep, 2015 Jul 21 , 12 (359-60).

19

Sun J et al. UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis.
Cell Rep, 2015 Jul 21 , 12 (449-61).

20

Padula AE et al. KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.
Neuropsychopharmacology, 2015 Jul , 40 (1928-39).

21

Lu L et al. Regulation of Gene Transcription by Voltage-gated L-type Calcium Channel, Cav1.3.
J. Biol. Chem., 2015 Feb 20 , 290 (4663-76).

22

Church TW et al. Preferential assembly of heteromeric small conductance calcium-activated potassium channels.
Eur. J. Neurosci., 2015 Feb , 41 (305-15).

23

Gomis-Perez C et al. An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.
J. Cell. Sci., 2015 Aug 15 , 128 (3155-63).

24

Chen J et al. SjAPI-2 is the first member of a new neurotoxin family with Ascaris-type fold and KCNQ1 inhibitory activity.
Int. J. Biol. Macromol., 2015 Aug , 79 (504-10).

25

Aidi-Knani S et al. Correspondences between the binding characteristics of a non-natural peptide, Lei-Dab7, and the distribution of SK subunits in the rat central nervous system.
Eur. J. Pharmacol., 2015 Apr 5 , 752 (106-11).

26

Bittner S et al. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms.
Int J Mol Sci, 2015 , 16 (16880-96).

27

Murthy SR et al. Small-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory.
PLoS ONE, 2015 , 10 (e0127264).

28

Kim SH et al. Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium.
Sci Rep, 2015 , 5 (18110).

29

Tang YR et al. Estrogen regulates the expression of small-conductance Ca-activated K+ channels in colonic smooth muscle cells.
Digestion, 2015 , 91 (187-96).

30

Wang K et al. Apamin Boosting of Synaptic Potentials in CaV2.3 R-Type Ca2+ Channel Null Mice.
PLoS ONE, 2015 , 10 (e0139332).

31

Egorova PA et al. [The effect of modulators of SK channels on simple spike firing frequency in the discharge of the cerebellar Purkinje cells in laboratory mice].
Zh. Evol. Biokhim. Fiziol., 2014 Mar-Apr , 50 (102-8).

32

García-Negredo G et al. Coassembly and coupling of SK2 channels and mGlu5 receptors.
J. Neurosci., 2014 Oct 29 , 34 (14793-802).

33

Orfila JE et al. Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation.
Eur. J. Neurosci., 2014 Oct , 40 (3179-88).

34

Shenton FC et al. Expression of transient receptor potential channels TRPC1 and TRPV4 in venoatrial endocardium of the rat heart.
Neuroscience, 2014 May 16 , 267 (195-204).

35

Siwek ME et al. The CaV2.3 R-type voltage-gated Ca2+ channel in mouse sleep architecture.
Sleep, 2014 May , 37 (881-92).

36

Guéguinou M et al. KCa and Ca(2+) channels: The complex thought.
Biochim. Biophys. Acta, 2014 Mar 6 , ().

37

Terentyev D et al. Sarcoplasmic reticulum Ca²⁺ release is both necessary and sufficient for SK channel activation in ventricular myocytes.
Am. J. Physiol. Heart Circ. Physiol., 2014 Mar 1 , 306 (H738-46).

38

Ballesteros-Merino C et al. Differential subcellular localization of SK3-containing channels in the hippocampus.
Eur. J. Neurosci., 2014 Mar , 39 (883-92).

39

Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

40

Rafizadeh S et al. Functional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channel.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jun 20 , ().

41

Fischl AM et al. Activity-dependent genes in mouse olfactory sensory neurons.
Chem. Senses, 2014 Jun , 39 (439-49).

42

Skibsbye L et al. Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria.
Cardiovasc. Res., 2014 Jul 1 , 103 (156-67).

43

Wang H et al. [Effects of intracellular calcium alteration on SK currents in atrial cardiomyocytes from patients with atrial fibrillation].
Zhongguo Ying Yong Sheng Li Xue Za Zhi, 2014 Jul , 30 (296-300, 305).

44

Scholl ES et al. Alternative splice isoforms of small conductance calcium-activated SK2 channels differ in molecular interactions and surface levels.
Channels (Austin), 2014 Jan 6 , 8 ().

45

Seo K et al. Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jan 28 , 111 (1551-6).

46

El Hachmane MF et al. Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor α.
J. Biol. Chem., 2014 Jan 17 , 289 (1388-401).

47

Fakira AK et al. Increased small conductance calcium-activated potassium type 2 channel-mediated negative feedback on N-methyl-D-aspartate receptors impairs synaptic plasticity following context-dependent sensitization to morphine.
Biol. Psychiatry, 2014 Jan 15 , 75 (105-14).

48

Pankey EA et al. Analysis of responses to the TRPV4 agonist GSK1016790A in the pulmonary vascular bed of the intact-chest rat.
Am. J. Physiol. Heart Circ. Physiol., 2014 Jan 1 , 306 (H33-40).

49

Fuchs PA et al. Ultrastructure of cisternal synapses on outer hair cells of the mouse cochlea.
J. Comp. Neurol., 2014 Feb 15 , 522 (717-29).

50

Yu K et al. Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin.
J. Gen. Physiol., 2014 Feb , 143 (253-67).

51

Halling DB et al. Calcium-dependent stoichiometries of the KCa2.2 (SK) intracellular domain/calmodulin complex in solution.
J. Gen. Physiol., 2014 Feb , 143 (231-52).

52

Haugaard MM et al. Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.
Heart Rhythm, 2014 Dec 24 , ().

53

Badarau E et al. Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration.
Bioorg. Med. Chem. Lett., 2014 Dec 15 , 24 (5616-20).

54

Morty RE et al. TRPV4: an exciting new target to promote alveolocapillary barrier function.
Am. J. Physiol. Lung Cell Mol. Physiol., 2014 Dec 1 , 307 (L817-21).

55

Dufour MA et al. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.
J. Neurosci. Res., 2014 Aug , 92 (981-99).

56

Gymnopoulos M et al. Developmental mapping of small-conductance calcium-activated potassium channel expression in the rat nervous system.
J. Comp. Neurol., 2014 Apr 1 , 522 (1072-101).

57

McAlexander MA et al. Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes.
J. Pharmacol. Exp. Ther., 2014 Apr , 349 (118-25).

58

Liégeois JF et al. Bis-(1,2,3,4-tetrahydroisoquinolinium): a chiral scaffold for developing high-affinity ligands for SK channels.
ChemMedChem, 2014 Apr , 9 (737-40).

59

Shenton F et al. A study of the expression of small conductance calcium-activated potassium channels (SK1-3) in sensory endings of muscle spindles and lanceolate endings of hair follicles in the rat.
PLoS ONE, 2014 , 9 (e107073).

60

Mu YH et al. RyR2 modulates a Ca2+-activated K+ current in mouse cardiac myocytes.
PLoS ONE, 2014 , 9 (e94905).

61

Dolga AM et al. Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.
Cell Death Dis, 2014 , 5 (e999).

62

Wedemeyer C et al. Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses.
J. Neurosci., 2013 Sep 25 , 33 (15477-87).

63

Anwar H et al. Stochastic Calcium Mechanisms Cause Dendritic Calcium Spike Variability.
J. Neurosci., 2013 Oct 2 , 33 (15848-15867).

64

Qi XY et al. Role of Small Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog.
Circulation, 2013 Nov 4 , ().

65

Dobbins RL et al. GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus.
Diabetes Obes Metab, 2013 Nov , 15 (1013-21).

66

Johnson SL et al. Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity.
Proc. Natl. Acad. Sci. U.S.A., 2013 May 21 , 110 (8720-5).

67

Maison SF et al. Olivocochlear suppression of outer hair cells in vivo: evidence for combined action of BK and SK2 channels throughout the cochlea.
J. Neurophysiol., 2013 Mar , 109 (1525-34).

68

Takai J et al. Laminar shear stress upregulates endothelial Ca2+-activated K+ channels KCa2.3 and KCa3.1 via a Ca2+/calmodulin-dependent protein kinase kinase/Akt/p300 cascade.
Am. J. Physiol. Heart Circ. Physiol., 2013 Jun 21 , ().

69

Shen MJ et al. Low-level vagus nerve stimulation upregulates small conductance calcium-activated potassium channels in the stellate ganglion.
Heart Rhythm, 2013 Jun , 10 (910-5).

70

Morales P et al. Contribution of the KCa3.1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process.
J. Gen. Physiol., 2013 Jul , 142 (37-60).

71

Indriati DW et al. Quantitative localization of Cav2.1 (P/Q-type) voltage-dependent calcium channels in Purkinje cells: somatodendritic gradient and distinct somatic coclustering with calcium-activated potassium channels.
J. Neurosci., 2013 Feb 20 , 33 (3668-78).

72

Dilly S et al. The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels.
Biochem. Pharmacol., 2013 Feb 15 , 85 (560-9).

73

Wulff H et al. Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets.
J. Cardiovasc. Pharmacol., 2013 Feb , 61 (102-12).

74

Chang PC et al. Heterogeneous upregulation of apamin-sensitive potassium currents in failing human ventricles.
J Am Heart Assoc, 2013 Feb , 2 (e004713).

75

Ma TF et al. A selective M1 and M3 receptor antagonist, penehyclidine hydrochloride, prevents postischemic LTP: involvement of NMDA receptors.
Synapse, 2013 Dec , 67 (865-74).

76

Pagadala P et al. Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels.
J. Neurosci., 2013 Aug 14 , 33 (13425-30).

77

Zhu R et al. Chronic hypoxia inhibits pregnancy-induced upregulation of SKCa channel expression and function in uterine arteries.
Hypertension, 2013 Aug , 62 (367-74).

78

Kim JJ et al. Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.
J. Hum. Genet., 2013 Aug , 58 (521-5).

79

Dolga AM et al. Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.
J. Biol. Chem., 2013 Apr 12 , 288 (10792-804).

80

Parajuli SP et al. NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels.
Br. J. Pharmacol., 2013 Apr , 168 (1611-25).

81

Benton DC et al. The relationship between functional inhibition and binding for K(Ca)2 channel blockers.
PLoS ONE, 2013 , 8 (e73328).

82

Turker I et al. Amiodarone inhibits apamin-sensitive potassium currents.
PLoS ONE, 2013 , 8 (e70450).

83

Zhou T et al. Two distinct channels mediated by m2mAChR and α9nAChR co-exist in type II vestibular hair cells of guinea pig.
Int J Mol Sci, 2013 , 14 (8818-31).

84

Wimmer RD et al. Sustaining sleep spindles through enhanced SK2-channel activity consolidates sleep and elevates arousal threshold.
J. Neurosci., 2012 Oct 3 , 32 (13917-28).

85

Kasumu AW et al. Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type 2.
Chem. Biol., 2012 Oct 26 , 19 (1340-53).

86

Huh D et al. A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.
Sci Transl Med, 2012 Nov 7 , 4 (159ra147).

87

Thorneloe KS et al. An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.
Sci Transl Med, 2012 Nov 7 , 4 (159ra148).

88

Peng HY et al. Glucocorticoid mediates water avoidance stress-sensitized colon-bladder cross-talk via RSK2/PSD-95/NR2B in rats.
Am. J. Physiol. Endocrinol. Metab., 2012 Nov 1 , 303 (E1094-106).

89

Zhang M et al. Structural basis for calmodulin as a dynamic calcium sensor.
Structure, 2012 May 9 , 20 (911-23).

90

Wang H et al. [Application of recording SK2 current in human atrial myocytes by perforated patch clamp techniques with the mix of beta-escin and amphotericin B].
Zhongguo Ying Yong Sheng Li Xue Za Zhi, 2012 May , 28 (214-8).

91

Marsh B et al. Leak K⁺ channel mRNAs in dorsal root ganglia: relation to inflammation and spontaneous pain behaviour.
Mol. Cell. Neurosci., 2012 Mar , 49 (375-86).

92

Chakroborty S et al. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice.
J. Neurosci., 2012 Jun 13 , 32 (8341-53).

93

Ballesteros-Merino C et al. Developmental profile of SK2 channel expression and function in CA1 neurons.
Hippocampus, 2012 Jun , 22 (1467-80).

94

Ohtsuki G et al. SK2 channel modulation contributes to compartment-specific dendritic plasticity in cerebellar Purkinje cells.
Neuron, 2012 Jul 12 , 75 (108-20).

95

Tan XQ et al. [Construction and identification of the expression plasmid of SK2 (KCNN2) gene from human atrial myocytes with overlapping PCR].
Zhongguo Ying Yong Sheng Li Xue Za Zhi, 2012 Jul , 28 (381-4).

96

Schulz R et al. Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents.
Neurobiol. Dis., 2012 Jan , 45 (337-47).

97

Dolga AM et al. Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia.
Glia, 2012 Dec , 60 (2050-64).

98

Deignan J et al. SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons.
Neuroscience, 2012 Aug 16 , 217 (67-76).

99

Afeli SA et al. SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions.
Am. J. Physiol. Renal Physiol., 2012 Aug 15 , 303 (F559-68).

100

McKay BM et al. Increasing SK2 channel activity impairs associative learning.
J. Neurophysiol., 2012 Aug 1 , 108 (863-70).

101

Girault A et al. Targeting SKCa channels in cancer: potential new therapeutic approaches.
Curr. Med. Chem., 2012 , 19 (697-713).

102

Kwee LC et al. A high-density genome-wide association screen of sporadic ALS in US veterans.
PLoS ONE, 2012 , 7 (e32768).

103

Wersinger E et al. Modulation of hair cell efferents.
Hear. Res., 2011 Sep , 279 (1-12).

104

Roux I et al. Onset of cholinergic efferent synaptic function in sensory hair cells of the rat cochlea.
J. Neurosci., 2011 Oct 19 , 31 (15092-101).

105

Weatherall KL et al. Crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of small-conductance calcium-activated potassium (SK) channels.
Proc. Natl. Acad. Sci. U.S.A., 2011 Nov 8 , 108 (18494-9).

106

Badarau E et al. Synthesis and radioligand binding studies of bis-(8-isopropyl-isoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels.
Bioorg. Med. Chem. Lett., 2011 Nov 15 , 21 (6756-9).

107

Girault A et al. New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Curr Cancer Drug Targets, 2011 Nov , 11 (1111-25).

108

Stanley DA et al. Stochastic amplification of calcium-activated potassium currents in Ca2+ microdomains.
J Comput Neurosci, 2011 Nov , 31 (647-66).

109

Bobak N et al. Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels.
, 2011 May 5 , ().

110

Wang W et al. Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons.
Neuropharmacology, 2011 May , 60 (901-9).

111

Mehmood T et al. Transcriptome profile reveals AMPA receptor dysfunction in the hippocampus of the Rsk2-knockout mice, an animal model of Coffin-Lowry syndrome.
Hum. Genet., 2011 Mar , 129 (255-69).

112

Yu T et al. [Expression and functional role of small conductance Ca(2+)-activated K(+) channels in human atrial myocytes].
Nan Fang Yi Ke Da Xue Xue Bao, 2011 Mar , 31 (490-4).

113

Park KS et al. Identification and functional characterization of ion channels in CD34(+) hematopoietic stem cells from human peripheral blood.
, 2011 Jun 1 , ().

114

Allen D et al. The SK2-long isoform directs synaptic localization and function of SK2-containing channels.
Nat. Neurosci., 2011 Jun , 14 (744-9).

115

Firth AL et al. Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels.
Pulm Circ, 2011 Jan 1 , 1 (48-71).

116

Yamazaki D et al. Contribution of K(ir)2 potassium channels to ATP-induced cell death in brain capillary endothelial cells and reconstructed HEK293 cell model.
Am. J. Physiol., Cell Physiol., 2011 Jan , 300 (C75-86).

117

Li ML et al. [Increased small conductance calcium-activated potassium channel (SK2 channel) current in atrial myocytes of patients with persistent atrial fibrillation].
Zhonghua Xin Xue Guan Bing Za Zhi, 2011 Feb , 39 (147-51).

118

Yu T et al. Decreased expression of small-conductance Ca(2+)-activated K(+) channels SK1 and SK2 in human chronic atrial fibrillation.
, 2011 Dec 1 , ().

119

Allen D et al. SK2 channels are neuroprotective for ischemia-induced neuronal cell death.
J. Cereb. Blood Flow Metab., 2011 Dec , 31 (2302-12).

120

Fortin DL et al. Optogenetic photochemical control of designer K+ channels in mammalian neurons.
, 2011 Apr 27 , ().

121

Mulholland PJ et al. Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses.
Biol. Psychiatry, 2011 Apr 1 , 69 (625-32).

122

Dolga AM et al. KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia.
Cell Death Dis, 2011 , 2 (e147).

123

Bittner S et al. Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients.
Arthritis Res. Ther., 2011 , 13 (R21).

124

Rinaldo L et al. Ataxias and cerebellar dysfunction: involvement of synaptic plasticity deficits?
Funct. Neurol., 2010 Jul-Sep , 25 (135-9).

125

Zorrilla de San Martín J et al. Ca2+ and Ca2+-activated k+ channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse.
J. Neurosci., 2010 Sep 8 , 30 (12157-67).

126

Lin MT et al. Coupled activity-dependent trafficking of synaptic SK2 channels and AMPA receptors.
J. Neurosci., 2010 Sep 1 , 30 (11726-34).

127

Lamy C et al. The sigma agonist 1,3-di-o-tolyl-guanidine directly blocks SK channels in dopaminergic neurons and in cell lines.
Eur. J. Pharmacol., 2010 Sep 1 , 641 (23-8).

128

Tuteja D et al. Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.
Circ. Res., 2010 Oct 1 , 107 (851-9).

129

Kita M et al. Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2010 May , 298 (R1310-9).

130

Hopf FW et al. Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence.
Neuron, 2010 Mar 11 , 65 (682-94).

131

Vick KA et al. In vivo pharmacological manipulation of small conductance Ca(2+)-activated K(+) channels influences motor behavior, object memory and fear conditioning.
Neuropharmacology, 2010 Mar , 58 (650-9).

132

Lee AL et al. Neighbor effects of neurons bearing protective transgenes.
Brain Res., 2010 Jun 21 , 1339 (70-5).

133

Bittner S et al. Upregulation of K2P5.1 potassium channels in multiple sclerosis.
Ann. Neurol., 2010 Jul , 68 (58-69).

134

Gestreau C et al. Task2 potassium channels set central respiratory CO2 and O2 sensitivity.
Proc. Natl. Acad. Sci. U.S.A., 2010 Feb 2 , 107 (2325-30).

135

Oliveira MS et al. Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats.
Brain Res., 2010 Aug 12 , 1348 (187-99).

136

Schlichter LC et al. The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro.
J Neuroinflammation, 2010 , 7 (4).

137

Abdullaev IF et al. Calcium-activated potassium channels BK and IK1 are functionally expressed in human gliomas but do not regulate cell proliferation.
PLoS ONE, 2010 , 5 (e12304).

138

Wersinger E et al. BK channels mediate cholinergic inhibition of high frequency cochlear hair cells.
PLoS ONE, 2010 , 5 (e13836).

139

Coulon P et al. Burst discharges in neurons of the thalamic reticular nucleus are shaped by calcium-induced calcium release.
Cell Calcium, 2009 Nov-Dec , 46 (333-46).

140

Taranda J et al. Constitutive expression of the alpha10 nicotinic acetylcholine receptor subunit fails to maintain cholinergic responses in inner hair cells after the onset of hearing.
J. Assoc. Res. Otolaryngol., 2009 Sep , 10 (397-406).

141

Hougaard C et al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment.
Mol. Pharmacol., 2009 Sep , 76 (569-78).

142

Lu L et al. Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel).
Proc. Natl. Acad. Sci. U.S.A., 2009 Oct 27 , 106 (18402-7).

143

Goodchild SJ et al. Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues.
J. Gen. Physiol., 2009 Oct , 134 (295-308).

144

Phan MN et al. Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes.
Arthritis Rheum., 2009 Oct , 60 (3028-37).

145

Nagy N et al. Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
J. Mol. Cell. Cardiol., 2009 Nov , 47 (656-63).

146

N'Gouemo P et al. Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat.
Brain Res., 2009 May 13 , 1270 (107-11).

147

Waring DW et al. Ca2+-activated K+ channels in gonadotropin-releasing hormone-stimulated mouse gonadotrophs.
Endocrinology, 2009 May , 150 (2264-72).

148

Chandler NJ et al. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker.
Circulation, 2009 Mar 31 , 119 (1562-75).

149

Li N et al. Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation.
J. Physiol. (Lond.), 2009 Mar 1 , 587 (1087-100).

150

Murthy V et al. SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells.
Mol. Cell. Neurosci., 2009 Jan , 40 (39-49).

151

Sankaranarayanan A et al. Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.
Mol. Pharmacol., 2009 Feb , 75 (281-95).

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