Kv7.1

1

Lang CN et al. Transgenic rabbit models to investigate the cardiac ion channel disease long QT syndrome.
Prog. Biophys. Mol. Biol., 2016 May 19 , ().

2

Lan X et al. Grafting voltage and pharmacological sensitivity in potassium channels.
Cell Res., 2016 May 13 , ().

3

Ali A et al. Heat shock protein 70 gene polymorphisms' influence on the electrophysiology of long QT syndrome.
J Interv Card Electrophysiol, 2016 Mar , 45 (119-30).

4

Jiang M et al. JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy.
Heart Rhythm, 2016 Mar , 13 (743-752).

5

Carbonell-Pascual B et al. Comparison between Hodgkin-Huxley and Markov formulations of cardiac ion channels.
J. Theor. Biol., 2016 Jun 21 , 399 (92-102).

6

Yamaguchi Y et al. Latent pathogenicity of the G38S polymorphism of KCNE1 K(+) channel modulator.
Heart Vessels, 2016 Jun 2 , ().

7

Izumi G et al. Compound Mutations Cause Increased Cardiac Events in Children with Long QT Syndrome: Can the Sequence Homology-Based Tools be Applied for Prediction of Phenotypic Severity?
Pediatr Cardiol, 2016 Jun , 37 (962-70).

8

Wu W et al. Molecular Basis of Cardiac Delayed Rectifier Potassium Channel Function and Pharmacology.
Card Electrophysiol Clin, 2016 Jun , 8 (275-84).

9

Major P et al. A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.
Br. J. Pharmacol., 2016 Jun , 173 (2046-61).

10

Roy PM et al. Anaesthesia management of a case of Jervell and Lange-Nielsen syndrome for minimally invasive bilateral thoracoscopic cervicothoracic sympathectomy.
Indian J Anaesth, 2016 Jun , 60 (424-6).

11

Shao H et al. [Relationship between electrocardiographic and genetic mutation (MYH7-H1717Q, MYLK2-K324E and KCNQ1-R190W) phenotype in patients with hypertrophic cardiomyopathy].
Zhonghua Xin Xue Guan Bing Za Zhi, 2016 Jan 24 , 44 (50-4).

12

Bodi I et al. Mechanisms of acquired long-QT syndrome in patients with propionic acidemia.
Heart Rhythm, 2016 Feb 5 , ().

13

Al-Hazza A et al. Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis.
Biochem. Biophys. Res. Commun., 2016 Feb 5 , 470 (473-8).

14

Neubauer J et al. Post-mortem whole-exome sequencing (WES) with a focus on cardiac disease-associated genes in five young sudden unexplained death (SUD) cases.
Int. J. Legal Med., 2016 Feb 4 , ().

15

Fang P et al. [Progress in research on defective protein trafficking and functional restoration in HERG-associated long QT syndrome].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2016 Feb , 33 (101-4).

16

Rannals MD et al. Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.
Neuron, 2016 Apr 6 , 90 (43-55).

17

Crumb WJ et al. An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel.
J Pharmacol Toxicol Methods, 2016 Apr 6 , ().

18

Choi JI et al. α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.
PLoS ONE, 2016 , 11 (e0152355).

19

Cubeddu LX Drug-induced Inhibition and Trafficking Disruption of ion Channels: Pathogenesis of QT Abnormalities and Drug-induced Fatal Arrhythmias.
Curr Cardiol Rev, 2016 , 12 (141-54).

20

Murray CI et al. Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4.
Elife, 2016 , 5 ().

21

Ichikawa M et al. Multigenerational Inheritance of Long QT Syndrome Type 2 in a Japanese Family.
Intern. Med., 2016 , 55 (259-62).

22

Zhao Y et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells.
BMC Cardiovasc Disord, 2016 , 16 (1).

23

Ware WA et al. Sudden death associated with QT interval prolongation and KCNQ1 gene mutation in a family of English Springer Spaniels.
J. Vet. Intern. Med., 2015 Mar-Apr , 29 (561-8).

24

Neverisky DL et al. Ion channel-transporter interactions.
Crit. Rev. Biochem. Mol. Biol., 2015 Jul-Aug , 51 (257-67).

25

Neethling A et al. Filamin C: a novel component of the KCNE2 interactome during hypoxia.
Cardiovasc J Afr, 2015 Jan-Feb , 27 (4-11).

26

Hertz CL et al. Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases.
Eur. J. Hum. Genet., 2015 Sep 9 , ().

27

Coll M et al. Genetic investigation of sudden unexpected death in epilepsy cohort by panel target resequencing.
Int. J. Legal Med., 2015 Sep 30 , ().

28

Abbott GW KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulation.
Gene, 2015 Sep 26 , ().

29

El-Sherif N et al. Role of pharmacotherapy in cardiac ion channelopathies.
Pharmacol. Ther., 2015 Sep 12 , ().

30

Provence A et al. The Novel KV7.2/KV7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility.
J. Pharmacol. Exp. Ther., 2015 Sep , 354 (290-301).

31

Hu Y et al. Engineering a peptide inhibitor towards the KCNQ1/KCNE1 potassium channel (IKs).
Peptides, 2015 Sep , 71 (77-83).

32

Sahu ID et al. Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.
Biochemistry, 2015 Oct 20 , 54 (6402-12).

33

Frea S et al. New echocardiographic insights in short QT syndrome: More than a channelopathy?
Heart Rhythm, 2015 Oct , 12 (2096-105).

34

Andersen MN et al. Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking.
Am. J. Physiol., Cell Physiol., 2015 Nov 15 , 309 (C693-706).

35

Kang Y et al. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Biochem. J., 2015 Nov 15 , 472 (71-82).

36

Bakker B et al. A Girl With Beckwith-Wiedemann Syndrome and Pseudohypoparathyroidism Type 1B Due to Multiple Imprinting Defects.
J. Clin. Endocrinol. Metab., 2015 Nov , 100 (3963-6).

37

Zoledziewska M et al. Height-reducing variants and selection for short stature in Sardinia.
Nat. Genet., 2015 Nov , 47 (1352-6).

38

Powell KL et al. In response: LQT, HCN, and epilepsy model.
Epilepsia, 2015 Nov , 56 (1855-6).

39

Kodirov SA LQT, HCN, and epilepsy model.
Epilepsia, 2015 Nov , 56 (1855).

40

Vassilakopoulou V et al. Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease.
Biochim. Biophys. Acta, 2015 Nov , 1850 (2168-76).

41

Liin SI et al. Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel.
Proc. Natl. Acad. Sci. U.S.A., 2015 May 5 , 112 (5714-9).

42

Qian Y et al. Joint effect of CENTD2 and KCNQ1 polymorphisms on the risk of type 2 diabetes mellitus among Chinese Han population.
Mol. Cell. Endocrinol., 2015 May 15 , 407 (46-51).

43

Matus M et al. Upregulation of SERCA2a following short-term ACE inhibition (by enalaprilat) alters contractile performance and arrhythmogenicity of healthy myocardium in rat.
Mol. Cell. Biochem., 2015 May , 403 (199-208).

44

Leren IS et al. Cardiac Mechanical Alterations and Genotype Specific Differences in Subjects With Long QT Syndrome.
JACC Cardiovasc Imaging, 2015 May , 8 (501-10).

45

Jahangir A et al. Strain Echocardiography and LQTS Subtypes: Mechanical Alterations in an Electrical Disorder.
JACC Cardiovasc Imaging, 2015 May , 8 (511-3).

46

Kolder IC et al. Analysis for Genetic Modifiers of Disease Severity in Patients with Long QT Syndrome Type 2.
Circ Cardiovasc Genet, 2015 Mar 3 , ().

47

Perry MD et al. Getting to the heart of hERG K(+) channel gating.
J. Physiol. (Lond.), 2015 Mar 27 , ().

48

Goodchild SJ et al. Sequence of gating charge movement and pore gating in HERG activation and deactivation pathways.
Biophys. J., 2015 Mar 24 , 108 (1435-47).

49

Biliczki P et al. The interaction between delayed rectifier channel alpha-subunits does not involve hetero-tetramer formation.
Naunyn Schmiedebergs Arch. Pharmacol., 2015 Mar 20 , ().

50

Steffensen AB et al. IKs Gain- and Loss-of-Function In Early-Onset Lone Atrial Fibrillation.
J. Cardiovasc. Electrophysiol., 2015 Mar 19 , ().

51

Villoutreix BO et al. Computational investigations of hERG channel blockers: New insights and current predictive models.
Adv. Drug Deliv. Rev., 2015 Mar 12 , ().

52

Laurentino S et al. Epigenetic germline mosaicism in infertile men.
Hum. Mol. Genet., 2015 Mar 1 , 24 (1295-304).

53

Gómez-Úriz AM et al. Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells.
Hum. Mol. Genet., 2015 Mar 1 , 24 (1432-40).

54

Wang W et al. Identification of a key residue in Kv7.1 potassium channel essential for sensing external potassium ions.
J. Gen. Physiol., 2015 Mar , 145 (201-12).

55

Hiippala A et al. Expanding the phenotype of Timothy syndrome type 2: an adolescent with ventricular fibrillation but normal development.
Am. J. Med. Genet. A, 2015 Mar , 167A (629-34).

56

Huang J et al. Genetic variants in KCNE1, KCNQ1, and NOS1AP in sudden unexplained death during daily activities in Chinese Han population.
J. Forensic Sci., 2015 Mar , 60 (351-6).

57

Wemhöner K et al. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.
J. Mol. Cell. Cardiol., 2015 Mar , 80 (186-95).

58

Stott JB et al. Contribution of kv7 channels to natriuretic Peptide mediated vasodilation in normal and hypertensive rats.
Hypertension, 2015 Mar , 65 (676-82).

59

Yang L et al. Intravenous anesthetic propofol inhibits multiple human cardiac potassium channels.
Anesthesiology, 2015 Mar , 122 (571-84).

60

Hayashi K et al. Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.
Circ Arrhythm Electrophysiol, 2015 Jun 30 , ().

61

Liin SI et al. The KCNQ1 channel - remarkable flexibility in gating allows for functional versatility.
J. Physiol. (Lond.), 2015 Jun 15 , 593 (2605-15).

62

Fu Y et al. Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.
Birth Defects Res. Part A Clin. Mol. Teratol., 2015 Jun , 103 (471-8).

63

Mills TA et al. Activation of KV7 channels stimulates vasodilatation of human placental chorionic plate arteries.
Placenta, 2015 Jun , 36 (638-44).

64

Kouvaros S et al. Hippocampal sharp waves and ripples: Effects of aging and modulation by NMDA receptors and L-type Ca2+ channels.
Neuroscience, 2015 Jul 9 , 298 (26-41).

65

Asahara S et al. Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c.
Proc. Natl. Acad. Sci. U.S.A., 2015 Jul 7 , 112 (8332-7).

66

Stattin EL et al. Genetic screening in sudden cardiac death in the young can save future lives.
Int. J. Legal Med., 2015 Jul 31 , ().

67

Harrell DT et al. Genotype-dependent differences in age of manifestation and arrhythmia complications in short QT syndrome.
Int. J. Cardiol., 2015 Jul 1 , 190 (393-402).

68

Wu ZJ et al. Characterization of a Chinese KCNQ1 mutation (R259H) that shortens repolarization and causes short QT syndrome 2.
J Geriatr Cardiol, 2015 Jul , 12 (394-401).

69

Kienitz MC et al. Synergistic modulation of KCNQ1/KCNE1 K(+) channels (IKs) by phosphatidylinositol 4,5-bisphosphate (PIP2) and [ATP]i.
Cell. Signal., 2015 Jul , 27 (1457-68).

70

Issa NP et al. QT interval prolongation in a patient with LQT2 on levetiracetam.
Seizure, 2015 Jul , 29 (134-6).

71

Kohl B et al. Solid phase synthesis, NMR structure determination of α-KTx3.8, its in silico docking to Kv1.x potassium channels, and electrophysiological analysis provide insights into toxin-channel selectivity.
Toxicon, 2015 Jul , 101 (70-8).

72

Hiramoto M et al. Comparative analysis of type 2 diabetes-associated SNP alleles identifies allele-specific DNA-binding proteins for the KCNQ1 locus.
Int. J. Mol. Med., 2015 Jul , 36 (222-30).

73

Yoshizawa S et al. Pyrrole-imidazole polyamide-mediated silencing of KCNQ1OT1 expression induces cell death in Wilms' tumor cells.
Int. J. Oncol., 2015 Jul , 47 (115-21).

74

Li L et al. Genetic variants of potassium voltage-gated channel genes (KCNQ1, KCNH2, and KCNE1) affected the risk of atrial fibrillation in elderly patients.
Genet Test Mol Biomarkers, 2015 Jul , 19 (359-65).

75

Vucic E et al. Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1.
Pflugers Arch., 2015 Jul , 467 (1457-68).

76

Xu Y et al. Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments.
Biophys. J., 2015 Jan 6 , 108 (62-75).

77

Zhang J et al. Electrophysiological and trafficking defects of the SCN5A T353I mutation in Brugada syndrome are rescued by alpha-allocryptopine.
Eur. J. Pharmacol., 2015 Jan 5 , 746 (333-43).

78

Chong E et al. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Heart Rhythm, 2015 Jan 30 , ().

79

Nakajo K et al. KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain.
J. Physiol. (Lond.), 2015 Jan 21 , ().

80

Gayen S et al. Structural analysis of the S4-S5 linker of the human KCNQ1 potassium channel.
Biochem. Biophys. Res. Commun., 2015 Jan 2 , 456 (410-4).

81

ter Bekke RM et al. Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk.
Eur. Heart J., 2015 Jan 14 , 36 (179-86).

82

Sedivy V et al. Role of Kv7 channels in responses of the pulmonary circulation to hypoxia.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Jan 1 , 308 (L48-57).

83

Costello JP et al. Surgical cardiac denervation therapy for treatment of congenital ion channelopathies in pediatric patients: a contemporary, single institutional experience.
World J Pediatr Congenit Heart Surg, 2015 Jan , 6 (33-8).

84

Xiong Q et al. Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation.
J Am Heart Assoc, 2015 Jan , 4 (e001526).

85

Chen M et al. Pharmacogenomics of glinides.
Pharmacogenomics, 2015 Jan , 16 (45-60).

86

Riuró H et al. Genetic analysis, in silico prediction, and family segregation in long QT syndrome.
Eur. J. Hum. Genet., 2015 Jan , 23 (79-85).

87

Kim TY et al. Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1.
Heart Rhythm, 2015 Jan , 12 (220-8).

88

Schultz BM et al. Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain.
Nucleic Acids Res., 2015 Jan , 43 (745-59).

89

Porta A et al. Autonomic control of heart rate and QT interval variability influences arrhythmic risk in long QT syndrome type 1.
J. Am. Coll. Cardiol., 2015 Feb 3 , 65 (367-74).

90

Moreno C et al. Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains.
Cardiovasc. Res., 2015 Feb 1 , 105 (223-32).

91

O-Uchi J et al. Impaired IKs channel activation by Ca(2+)-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1.
J. Mol. Cell. Cardiol., 2015 Feb , 79 (203-11).

92

Tseng GN et al. Understanding the microscopic mechanisms for LQT1 needs a global view of the I(Ks) channel.
Heart Rhythm, 2015 Feb , 12 (395-6).

93

Eldstrom J et al. Microscopic mechanisms for long QT syndrome type 1 revealed by single-channel analysis of I(Ks) with S3 domain mutations in KCNQ1.
Heart Rhythm, 2015 Feb , 12 (386-94).

94

de Llano CT et al. Further evidence of the association between LQT syndrome and epilepsy in a family with KCNQ1 pathogenic variant.
Seizure, 2015 Feb , 25 (65-7).

95

Lee S et al. Heterogeneity in Kv7 channel function in the cerebral and coronary circulation.
Microcirculation, 2015 Feb , 22 (109-21).

96

Winbo A et al. Vestibular dysfunction is a clinical feature of the Jervell and Lange-Nielsen Syndrome.
Scand. Cardiovasc. J., 2015 Feb , 49 (7-13).

97

Anderson HN et al. Marked, transient, emotion-triggered QT accentuation in an adolescent female with type 1 long QT syndrome.
Cardiol Young, 2015 Feb , 25 (376-9).

98

Nekouzadeh A et al. Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1.
Prog. Biophys. Mol. Biol., 2015 Dec 30 , ().

99

Zhu W et al. Molecular motions that shape the cardiac action potential: Insights from voltage clamp fluorometry.
Prog. Biophys. Mol. Biol., 2015 Dec 25 , ().

100

Peters CH et al. Triggers for arrhythmogenesis in the Brugada and long QT 3 syndromes.
Prog. Biophys. Mol. Biol., 2015 Dec 20 , ().

101

Slaats GG et al. Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesis.
J. Cell. Sci., 2015 Dec 15 , 128 (4550-9).

102

Robyns T et al. Targeted capture sequencing in a large LQTS family reveals a new pathogenic mutation c.2038delG in KCNH2 initially missed due to allelic dropout.
Acta Cardiol, 2015 Dec , 70 (747-9).

103

Qureshi SF et al. Mutational analysis of SCN5A gene in long QT syndrome.
Meta Gene, 2015 Dec , 6 (26-35).

104

Kanters JK et al. Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family.
Scand. J. Clin. Lab. Invest., 2015 Dec , 75 (699-709).

105

Wasano K et al. A novel frameshift mutation in KCNQ4 in a family with autosomal recessive non-syndromic hearing loss.
Biochem. Biophys. Res. Commun., 2015 Aug 7 , 463 (582-6).

106

Zhi D et al. The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides.
Eur J Pharm Sci, 2015 Aug 30 , 76 (149-55).

107

Yuan J et al. Potassium channel KCNJ15 is required for histamine-stimulated gastric acid secretion.
Am. J. Physiol., Cell Physiol., 2015 Aug 15 , 309 (C264-70).

108

Anneken L et al. Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking.
Eur. Heart J., 2015 Aug 12 , ().

109

Koponen M et al. Follow-up of 316 molecularly defined pediatric long-QT syndrome patients: clinical course, treatments, and side effects.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (815-23).

110

Krönauer T et al. [Perioperative treatment of patients with long QT syndrome].
Anaesthesist, 2015 Aug , 64 (625-39).

111

Imam MH et al. A novel technique to investigate the effect of ageing on ventricular repolarization characteristics in healthy and LQTS subjects.
Conf Proc IEEE Eng Med Biol Soc, 2015 Aug , 2015 (2796-9).

112

Li G et al. RNA interference-based therapeutics for inherited long QT syndrome.
Exp Ther Med, 2015 Aug , 10 (395-400).

113

Krönauer T et al. [Long QT syndrome : History, genetics, clinical symptoms, causes and therapy].
Anaesthesist, 2015 Aug , 64 (586-95).

114

Winbo A et al. Third trimester fetal heart rate predicts phenotype and mutation burden in the type 1 long QT syndrome.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (806-14).

115

Potet F et al. Intracellular calcium attenuates late current conducted by mutant human cardiac sodium channels.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (933-41).

116

Chang Q et al. Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome.
EMBO Mol Med, 2015 Aug , 7 (1077-86).

117

Lampert R Reassuring News for Genetically Tested, Appropriately Treated, Low-Risk LQTS Patients.
J. Cardiovasc. Electrophysiol., 2015 Aug , 26 (859-61).

118

Chen J et al. SjAPI-2 is the first member of a new neurotoxin family with Ascaris-type fold and KCNQ1 inhibitory activity.
Int. J. Biol. Macromol., 2015 Aug , 79 (504-10).

119

Osterbur ML et al. An Interdomain KCNH2 Mutation Produces an Intermediate Long QT Syndrome.
Hum. Mutat., 2015 Aug , 36 (764-73).

120

Zhang C et al. Identification of Low-Risk Adult Congenital LQTS Patients.
J. Cardiovasc. Electrophysiol., 2015 Aug , 26 (853-8).

121

Christ T et al. LQT1-phenotypes in hiPSC: Are we measuring the right thing?
Proc. Natl. Acad. Sci. U.S.A., 2015 Apr 21 , 112 (E1968).

122

Greber B et al. Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations.
Proc. Natl. Acad. Sci. U.S.A., 2015 Apr 21 , 112 (E1969).

123

Morales-Cano D et al. Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.
Cardiovasc. Res., 2015 Apr 1 , 106 (98-108).

124

Kapplinger JD et al. Enhancing the Predictive Power of Mutations in the C-Terminus of the KCNQ1-Encoded Kv7.1 Voltage-Gated Potassium Channel.
J Cardiovasc Transl Res, 2015 Apr , 8 (187-97).

125

Williams VS et al. Multiplex ligation-dependent probe amplification copy number variant analysis in patients with acquired long QT syndrome.
Europace, 2015 Apr , 17 (635-41).

126

Lau E et al. Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling.
PLoS ONE, 2015 , 10 (e0122754).

127

Kasimova MA et al. PIP₂-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6.
Sci Rep, 2015 , 5 (7474).

128

Kong X et al. The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes.
PLoS ONE, 2015 , 10 (e0143607).

129

Pedersen PJ et al. Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium.
PLoS ONE, 2015 , 10 (e0138320).

130

Ao D et al. The rs2237892 Polymorphism in KCNQ1 Influences Gestational Diabetes Mellitus and Glucose Levels: A Case-Control Study and Meta-Analysis.
PLoS ONE, 2015 , 10 (e0128901).

131

Mayo S et al. In Pursuit of New Imprinting Syndromes by Epimutation Screening in Idiopathic Neurodevelopmental Disorder Patients.
Biomed Res Int, 2015 , 2015 (341986).

132

Liu X et al. Effects of IGF2BP2, KCNQ1 and GCKR polymorphisms on clinical outcome in metastatic gastric cancer treated with EOF regimen.
Pharmacogenomics, 2015 , 16 (959-70).

133

Itoh H et al. A Common Mutation of Long QT Syndrome Type 1 in Japan.
Circ. J., 2015 , 79 (2026-30).

134

Inanobe A et al. An Epithelial Ca2+-Sensor Protein is an Alternative to Calmodulin to Compose Functional KCNQ1 Channels.
Cell. Physiol. Biochem., 2015 , 36 (1847-61).

135

Allegue C et al. Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.
PLoS ONE, 2015 , 10 (e0133037).

136

Abete I et al. Epigenetic Changes in the Methylation Patterns of KCNQ1 and WT1 after a Weight Loss Intervention Program in Obese Stroke Patients.
Curr Neurovasc Res, 2015 , 12 (321-33).

137

Koppes E et al. Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development.
PLoS ONE, 2015 , 10 (e0135202).

138

Warsi J et al. Regulation of Voltage Gated K+ Channel KCNE1/KCNQ1 by the Janus Kinase JAK3.
Cell. Physiol. Biochem., 2015 , 37 (2476-85).

139

Cazals Y et al. KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing.
Nat Commun, 2015 , 6 (8780).

140

Bellin M et al. Human iPS cell models of Jervell and Lange-Nielsen syndrome.
Rare Dis, 2015 , 3 (e1012978).

141

Huerta-Chagoya A et al. Genetic determinants for gestational diabetes mellitus and related metabolic traits in Mexican women.
PLoS ONE, 2015 , 10 (e0126408).

142

Hu RM et al. Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis.
PLoS ONE, 2015 , 10 (e0124921).

143

Liu QN et al. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
PLoS ONE, 2015 , 10 (e0123951).

144

Ma D et al. Characterization of a novel KCNQ1 mutation for type 1 long QT syndrome and assessment of the therapeutic potential of a novel IKs activator using patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Stem Cell Res Ther, 2015 , 6 (39).

145

Svalø J et al. Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction.
PLoS ONE, 2015 , 10 (e0117350).

146

Sun P et al. A distinct three-helix centipede toxin SSD609 inhibits I(ks) channels by interacting with the KCNE1 auxiliary subunit.
Sci Rep, 2015 , 5 (13399).

147

Chang YS et al. Mutation Analysis of KCNQ1, KCNH2 and SCN5A Genes in Taiwanese Long QT Syndrome Patients.
Int Heart J, 2015 , 56 (450-3).

148

Steffensen AB et al. High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance.
Sci Rep, 2015 , 5 (10009).

149

Al-Aama JY et al. Genotype-phenotype analysis of Jervell and Lange-Nielsen syndrome in six families from Saudi Arabia.
Clin. Genet., 2015 , 87 (74-9).

150

Leong IU et al. Assessment of the predictive accuracy of five in silico prediction tools, alone or in combination, and two metaservers to classify long QT syndrome gene mutations.
BMC Med. Genet., 2015 , 16 (34).

151

Lazzerini PE et al. Long QT Syndrome: An Emerging Role for Inflammation and Immunity.
Front Cardiovasc Med, 2015 , 2 (26).

152

Kılıç E et al. Jervell and Lange-Nielsen syndrome with homozygous missense mutation of the KCNQ1 gene.
Turk. J. Pediatr., 2014 Sep-Oct , 56 (542-5).

153

Lazaraviciute G et al. A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived spontaneously.
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