Kir3.2

1

Jorgensen C et al. Lateral Fenestrations in K(+)-Channels Explored Using Molecular Dynamics Simulations.
Mol. Pharm., 2016 May 26 , ().

2

Waterman M et al. Predictors of Outcome in Ulcerative Colitis.
Inflamm. Bowel Dis., 2015 Sep , 21 (2097-105).

3

Adney SK et al. A Critical Gating Switch at a Modulatory Site in Neuronal Kir3 Channels.
J. Neurosci., 2015 Oct 21 , 35 (14397-405).

4

Hablitz LM et al. GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin.
J. Neurosci., 2015 Nov 11 , 35 (14957-65).

5

Victoria NC et al. G Protein-Gated K+ Channel Ablation in Forebrain Pyramidal Neurons Selectively Impairs Fear Learning.
Biol. Psychiatry, 2015 Nov 10 , ().

6

Kotecki L et al. GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner.
J. Neurosci., 2015 May 6 , 35 (7131-42).

7

Tatard-Leitman VM et al. Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability.
Biol. Psychiatry, 2015 Mar 15 , 77 (556-68).

8

Langford DJ et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery.
Pain, 2015 Mar , 156 (371-80).

9

Workman ER et al. Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η.
Mol. Psychiatry, 2015 Mar , 20 (298-310).

10

Thomson SJ et al. Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels.
J. Biol. Chem., 2015 Jun 5 , 290 (14528-35).

11

Tsantoulas C Emerging potassium channel targets for the treatment of pain.
Curr Opin Support Palliat Care, 2015 Jun , 9 (147-54).

12

Robertson DN et al. Design and construction of conformational biosensors to monitor ion channel activation: A prototype FlAsH/BRET-approach to Kir3 channels.
Methods, 2015 Jul 22 , ().

13

Blichowski M et al. The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.
Epilepsia, 2015 Jul , 56 (1081-7).

14

Masotti A et al. Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel encoded by KCNJ6.
Am. J. Hum. Genet., 2015 Feb 5 , 96 (295-300).

15

Lyu C et al. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy.
Mol Pain, 2015 , 11 (44).

16

Montalbano A et al. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
PLoS ONE, 2015 , 10 (e0140369).

17

Lim MS et al. Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells.
PLoS ONE, 2015 , 10 (e0138460).

18

Mayordomo-Cava J et al. Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus.
PLoS ONE, 2015 , 10 (e0134385).

19

Bagriantsev SN et al. Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries.
ACS Chem Neurosci, 2014 Sep 17 , 5 (812-22).

20

Hablitz LM et al. Suprachiasmatic nucleus function and circadian entrainment are modulated by G protein-coupled inwardly rectifying (GIRK) channels.
J. Physiol. (Lond.), 2014 Nov 15 , 592 (5079-92).

21

Wen W et al. Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas.
Bioorg. Med. Chem. Lett., 2014 Nov 1 , 24 (5102-6).

22

Munoz MB et al. Sorting nexin 27 regulation of G protein-gated inwardly rectifying K⁺ channels attenuates in vivo cocaine response.
Neuron, 2014 May 7 , 82 (659-69).

23

Kirizs T et al. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells.
Eur. J. Neurosci., 2014 Jun , 39 (1771-83).

24

Liu C et al. Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice.
Hum. Genet., 2014 Jun , 133 (743-53).

25

Xiong Y et al. Serum antibodies to microbial antigens for Crohn's disease progression: a meta-analysis.
Eur J Gastroenterol Hepatol, 2014 Jul , 26 (733-42).

26

Langford DJ et al. Variations in Potassium Channel Genes Are Associated With Breast Pain in Women Prior to Breast Cancer Surgery.
J. Neurogenet., 2014 Jan 7 , ().

27

Chung MK et al. Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.
Eur J Pain, 2014 Jan , 18 (29-38).

28

Kahanovitch U et al. Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.
J. Physiol. (Lond.), 2014 Dec 15 , 592 (5373-90).

29

Dragicevic E et al. Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.
Brain, 2014 Aug , 137 (2287-302).

30

Lalive AL et al. Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity.
J. Neurosci., 2014 Apr 9 , 34 (5107-14).

31

Mutua J et al. Functional diversity of voltage-sensing phosphatases in two urodele amphibians.
Physiol Rep, 2014 , 2 ().

32

Hartfield EM et al. Physiological characterisation of human iPS-derived dopaminergic neurons.
PLoS ONE, 2014 , 9 (e87388).

33

Nishizawa D et al. Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence.
J. Pharmacol. Sci., 2014 , 126 (253-63).

34

Wang W et al. Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.
Elife, 2014 , 3 (e03671).

35

Ramos-Hunter SJ et al. Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators.
Bioorg. Med. Chem. Lett., 2013 Sep 15 , 23 (5195-8).

36

van Schaik FD et al. Serological markers predict inflammatory bowel disease years before the diagnosis.
Gut, 2013 May , 62 (683-8).

37

Saenz del Burgo L et al. Chronic effects of corticosterone on GIRK1-3 subunits and 5-HT1A receptor expression in rat brain and their reversal by concurrent fluoxetine treatment.
Eur Neuropsychopharmacol, 2013 Mar , 23 (229-39).

38

Whorton MR et al. X-ray structure of the mammalian GIRK2-βγ G-protein complex.
Nature, 2013 Jun 13 , 498 (190-7).

39

Zylbergold P et al. A novel, radiolabel-free pulse chase strategy to study Kir3 channel ontogeny.
J. Recept. Signal Transduct. Res., 2013 Jun , 33 (144-52).

40

Torrecilla M et al. Role of GIRK channels on the noradrenergic transmission in vivo: an electrophysiological and neurochemical study on GIRK2 mutant mice.
Int. J. Neuropsychopharmacol., 2013 Jun , 16 (1093-104).

41

Nockemann D et al. The K(+) channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia.
EMBO Mol Med, 2013 Jul 1 , ().

42

Aguado C et al. Differential maturation of GIRK2-expressing neurons in the mouse cerebellum.
J. Chem. Neuroanat., 2013 Jan , 47 (79-89).

43

Richard-Lalonde M et al. Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.
Mol. Pharmacol., 2013 Feb , 83 (416-28).

44

Hilder TA et al. Conductance properties of the inwardly rectifying channel, Kir3.2: molecular and Brownian dynamics study.
Biochim. Biophys. Acta, 2013 Feb , 1828 (471-8).

45

Bruehl S et al. Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes.
Pain, 2013 Dec , 154 (2853-9).

46

Fajardo-Serrano A et al. Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.
Hippocampus, 2013 Dec , 23 (1231-45).

47

Wen W et al. Discovery of 'molecular switches' within a GIRK activator scaffold that afford selective GIRK inhibitors.
Bioorg. Med. Chem. Lett., 2013 Aug 15 , 23 (4562-6).

48

Edenberg HJ et al. Genetics and alcoholism.
Nat Rev Gastroenterol Hepatol, 2013 Aug , 10 (487-94).

49

Balana B et al. Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels.
PLoS ONE, 2013 , 8 (e59800).

50

Wallis D et al. Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitis: an observational study.
Arthritis Res. Ther., 2013 , 15 (R166).

51

Inanobe A et al. Conformational changes underlying pore dilation in the cytoplasmic domain of mammalian inward rectifier K+ channels.
PLoS ONE, 2013 , 8 (e79844).

52

Vidal V et al. Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome.
Neuroscience, 2012 Sep 18 , 220 (158-68).

53

Padgett CL et al. Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA.
Neuron, 2012 Mar 8 , 73 (978-89).

54

Cooper A et al. Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice.
Proc. Natl. Acad. Sci. U.S.A., 2012 Feb 14 , 109 (2642-7).

55

Best TK et al. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome.
Exp. Neurol., 2012 Feb , 233 (749-57).

56

Kleschevnikov AM et al. Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome.
Neurobiol. Dis., 2012 Feb , 45 (683-91).

57

Wydeven N et al. Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity.
Proc. Natl. Acad. Sci. U.S.A., 2012 Dec 26 , 109 (21492-7).

58

Kim JA et al. Electrophysiological, morphological, and topological properties of two histochemically distinct subpopulations of cerebellar unipolar brush cells.
Cerebellum, 2012 Dec , 11 (1012-25).

59

Reyes S et al. GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.
J. Comp. Neurol., 2012 Aug 15 , 520 (2591-607).

60

Kang SJ et al. Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.
Genes Brain Behav., 2012 Aug , 11 (712-9).

61

Fu Y et al. A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse.
Brain Struct Funct, 2012 Apr , 217 (591-612).

62

Lü Q et al. Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.
Mol Med Report, 2011 Sep-Oct , 4 (941-5).

63

Whorton MR et al. Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
Cell, 2011 Sep 30 , 147 (199-208).

64

Loscalzo LM et al. Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents.
Pharmacol. Biochem. Behav., 2011 Sep , 99 (333-41).

65

Inanobe A et al. INTERACTIONS OF CATIONS WITH THE CYTOPLASMIC PORES OF INWARD RECTIFIER K+ CHANNELS IN THE CLOSED STATE.
, 2011 Oct 9 , ().

66

Liu C et al. Genetic analysis of Down syndrome-associated heart defects in mice.
Hum. Genet., 2011 Nov , 130 (623-32).

67

Clarke TK et al. KCNJ6 is associated with adult alcohol dependence and involved in gene × early life stress interactions in adolescent alcohol drinking.
Neuropsychopharmacology, 2011 May , 36 (1142-8).

68

Yu JE et al. High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease.
Clin. Immunol., 2011 Jan , 138 (14-22).

69

Yamamoto T et al. Clinical manifestations of the deletion of Down syndrome critical region including DYRK1A and KCNJ6.
Am. J. Med. Genet. A, 2011 Jan , 155A (113-9).

70

Lazary J et al. Epistatic interaction of CREB1 and KCNJ6 on rumination and negative emotionality.
Eur Neuropsychopharmacol, 2011 Jan , 21 (63-70).

71

Yi YJ et al. Sperm GIRK2-Containing K(+) Inward Rectifying Channels Participate in Sperm Capacitation and Fertilization.
Syst Biol Reprod Med, 2011 Dec , 57 (296-308).

72

Fernandez-Alacid L et al. Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain.
Eur. J. Neurosci., 2011 Dec , 34 (1724-36).

73

Arora D et al. Acute cocaine exposure weakens GABA(B) receptor-dependent G-protein-gated inwardly rectifying K+ signaling in dopamine neurons of the ventral tegmental area.
J. Neurosci., 2011 Aug 24 , 31 (12251-7).

74

Inanobe A et al. Inverse agonist-like action of cadmium on G-protein-gated inward-rectifier K(+) channels.
Biochem. Biophys. Res. Commun., 2011 Apr 8 , 407 (366-71).

75

White MD et al. A Molecular Toolbox for Rapid Generation of Viral Vectors to Up- or Down-Regulate Neuronal Gene Expression in vivo.
Front Mol Neurosci, 2011 , 4 (8).

76

Kobayashi T et al. Inhibition of g protein-activated inwardly rectifying k channels by different classes of antidepressants.
PLoS ONE, 2011 , 6 (e28208).

77

Arora D et al. Altered neurotransmission in the mesolimbic reward system of Girk mice.
J. Neurochem., 2010 Sep 1 , 114 (1487-97).

78

Nassirpour R et al. Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons.
J. Neurosci., 2010 Oct 6 , 30 (13419-30).

79

Lötsch J et al. Pharmacogenetics of new analgesics.
, 2010 Oct 13 , ().

80

Lötsch J et al. A KCNJ6 (Kir3.2, GIRK2) gene polymorphism modulates opioid effects on analgesia and addiction but not on pupil size.
Pharmacogenet. Genomics, 2010 May , 20 (291-7).

81

Summers KM et al. Mutations at KCNQ1 and an unknown locus cause long QT syndrome in a large Australian family: implications for genetic testing.
Am. J. Med. Genet. A, 2010 Mar , 152A (613-21).

82

Kobayashi T et al. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine.
Neuropsychopharmacology, 2010 Jun , 35 (1560-9).

83

Kleene R et al. Functional consequences of the interactions between the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB and the inwardly rectifying K+ channel Kir3.3.
, 2010 Jul 6 , ().

84

Berlin S et al. G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK).
J. Biol. Chem., 2010 Feb 26 , 285 (6179-85).

85

Styer AM et al. G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels.
J. Biol. Chem., 2010 Dec 31 , 285 (41290-9).

86

Inanobe A et al. A structural determinant for the control of PIP2 sensitivity in G protein-gated inward rectifier K+ channels.
J. Biol. Chem., 2010 Dec 3 , 285 (38517-23).

87

Aron L et al. Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons.
PLoS Biol., 2010 , 8 (e1000349).

88

Balana B et al. Mutagenesis and functional analysis of ion channels heterologously expressed in Mammalian cells.
J Vis Exp, 2010 , ().

89

Cramer NP et al. GABAB-GIRK2-mediated signaling in Down syndrome.
Adv. Pharmacol., 2010 , 58 (397-426).

90

Kamat A et al. Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation.
PLoS ONE, 2010 , 5 (e15533).

91

Gaillard A et al. Anatomical and functional reconstruction of the nigrostriatal pathway by intranigral transplants.
Neurobiol. Dis., 2009 Sep , 35 (477-88).

92

Markowitz J et al. Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?
Inflamm. Bowel Dis., 2009 May , 15 (714-9).

93

Aryal P et al. A discrete alcohol pocket involved in GIRK channel activation.
Nat. Neurosci., 2009 Jun 28 , ().

94

Fernández-Alacid L et al. Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.
J. Neurochem., 2009 Jun 22 , ().

95

Andereggen L et al. Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease.
Brain Res., 2009 Jun 18 , 1276 (39-49).

96

Rubinstein M et al. Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.
J. Physiol. (Lond.), 2009 Jul 15 , 587 (3473-91).

97

Chung HJ et al. Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels.
Proc. Natl. Acad. Sci. U.S.A., 2009 Jan 13 , 106 (629-34).

98

Chung HJ et al. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.
Proc. Natl. Acad. Sci. U.S.A., 2009 Jan 13 , 106 (635-40).

99

McGovern DP et al. MAGI2 genetic variation and inflammatory bowel disease.
Inflamm. Bowel Dis., 2009 Jan , 15 (75-83).

100

Garrison JB et al. TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.
Oncogene, 2009 Apr 2 , 28 (1584-93).

101

Robitaille M et al. Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes.
Cell. Signal., 2009 Apr , 21 (488-501).

102

Spiliopoulos K et al. Expression of GluR6 kainate receptor subunit in granular layer of weaver mouse cerebellum.
, 2009 Apr , 116 (417-22).

103

Nishizawa D et al. Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery.
PLoS ONE, 2009 , 4 (e7060).

104

Mundwiler ML et al. Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study.
Arthritis Res. Ther., 2009 , 11 (R177).

105

Saenz del Burgo L et al. Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.
J. Comp. Neurol., 2008 Oct 20 , 510 (581-606).

106

Sosulina L et al. Neuropeptide Y activates a G-protein-coupled inwardly rectifying potassium current and dampens excitability in the lateral amygdala.
Mol. Cell. Neurosci., 2008 Nov , 39 (491-8).

107

Best TK et al. Speeding of miniature excitatory post-synaptic currents in Ts65Dn cultured hippocampal neurons.
Neurosci. Lett., 2008 Jun 27 , 438 (356-61).

108

Pravetoni M et al. Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.
Genes Brain Behav., 2008 Jul , 7 (523-31).

109

Owsianowski E et al. Negative regulation of apoptosis in yeast.
Biochim. Biophys. Acta, 2008 Jul , 1783 (1303-10).

110

Ahangar N et al. Effects of gonadal steroid hormones on GIRK2 gene transcription in the rat central nervous system.
Neurosci. Lett., 2008 Feb 6 , 431 (201-5).

111

Torrecilla M et al. Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK-knockout mice.
Eur. J. Neurosci., 2008 Aug , 28 (618-24).

112

Cruz HG et al. Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.
J. Neurosci., 2008 Apr 9 , 28 (4069-77).

113

Lignon JM et al. Altered heart rate control in transgenic mice carrying the KCNJ6 gene of the human chromosome 21.
Physiol. Genomics, 2008 Apr 22 , 33 (230-9).

114

Aguado C et al. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum.
J. Neurochem., 2008 Apr , 105 (497-511).

115

Azanza MJ et al. Characterization by immunocytochemistry of ionic channels in Helix aspersa suboesophageal brain ganglia neurons.
Histol. Histopathol., 2008 Apr , 23 (397-406).

116

Inanobe A et al. Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
Channels (Austin), 2007 Jan-Feb , 1 (39-45).

117

Murata Y et al. Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2.
J. Physiol. (Lond.), 2007 Sep 15 , 583 (875-89).

118

Lunn ML et al. A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.
Nat. Neurosci., 2007 Oct , 10 (1249-59).

119

Papp M et al. [Relevance of serologic studies in inflammatory bowel diseases]
, 2007 May 13 , 148 (887-96).

120

Eulitz D et al. Heterogeneous distribution of kir3 potassium channel proteins within dopaminergic neurons in the mesencephalon of the rat brain.
Cell. Mol. Neurobiol., 2007 May , 27 (285-302).

121

Papadakis KA et al. Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations.
Inflamm. Bowel Dis., 2007 May , 13 (524-30).

122

Kuan WL et al. The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias.
Neurobiol. Dis., 2007 Mar , 25 (594-608).

123

Clancy SM et al. Coregulation of natively expressed pertussis toxin-sensitive muscarinic receptors with G-protein-activated potassium channels.
J. Neurosci., 2007 Jun 13 , 27 (6388-99).

124

Kobayashi T et al. Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes.
Toxicol In Vitro, 2007 Jun , 21 (656-64).

125

Borgal L et al. Differential effects of glial cell line-derived neurotrophic factor on A9 and A10 dopamine neuron survival in vitro.
Neuroscience, 2007 Jul 13 , 147 (712-9).

126

Saccone SF et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
Hum. Mol. Genet., 2007 Jan 1 , 16 (36-49).

127

Hara K et al. Inhibitory effect of gabapentin on N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
, 2007 Jan , 51 (122-8).

128

Best TK et al. Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.
J. Neurophysiol., 2007 Jan , 97 (892-900).

129

Kracke GR et al. The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes.
Naunyn Schmiedebergs Arch. Pharmacol., 2007 Dec , 376 (285-93).

130

Labouèbe G et al. RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.
Nat. Neurosci., 2007 Dec , 10 (1559-68).

131

Noels H et al. A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.
J. Biol. Chem., 2007 Apr 6 , 282 (10180-9).

132

Fowler CE et al. Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.
J. Physiol. (Lond.), 2007 Apr 1 , 580 (51-65).

133

Kawano T et al. Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.
Mol. Pharmacol., 2007 Apr , 71 (1179-84).

134

Steinecker B et al. The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J. Recept. Signal Transduct. Res., 2007 , 27 (369-82).

135

Harashima C et al. Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model.
Cell. Mol. Neurobiol., 2006 Jul-Aug , 26 (719-34).

136

Grabe M et al. K+ channel selectivity depends on kinetic as well as thermodynamic factors.
Proc. Natl. Acad. Sci. U.S.A., 2006 Sep 26 , 103 (14361-6).

137

Bichet D et al. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity.
Proc. Natl. Acad. Sci. U.S.A., 2006 Sep 26 , 103 (14355-60).

138

Strazielle C et al. Regional brain variations of cytochrome oxidase activity and motor coordination in Girk2(Wv) (Weaver) mutant mice.
Neuroscience, 2006 Oct 13 , 142 (437-49).

139

Marker CL et al. Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels.
J. Neurosci., 2006 Nov 22 , 26 (12251-9).

140

Jaén C et al. RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling.
J. Biol. Chem., 2006 Nov 10 , 281 (34549-60).

141

Shankar H et al. G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases.
Blood, 2006 Nov 1 , 108 (3027-34).

142

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine.
J. Pharmacol. Sci., 2006 Nov , 102 (278-87).

143

Del Re AM et al. Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes.
Brain Res., 2006 May 4 , 1087 (75-82).

144

Stasko MR et al. Hypothermic responses to 8-OH-DPAT in the Ts65Dn mouse model of Down syndrome.
Neuroreport, 2006 May 29 , 17 (837-41).

145

Thomas AM et al. Differential phosphoinositide binding to components of the G protein-gated K+ channel.
J. Membr. Biol., 2006 May , 211 (43-53).

146

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Neuropsychopharmacology, 2006 Mar , 31 (516-24).

147

Zhao Q et al. Dominant negative effects of a Gbeta mutant on G-protein coupled inward rectifier K+ channel.
FEBS Lett., 2006 Jul 10 , 580 (3879-82).

148

Pondugula SR et al. Glucocorticoid regulation of genes in the amiloride-sensitive sodium transport pathway by semicircular canal duct epithelium of neonatal rat.
Physiol. Genomics, 2006 Jan 12 , 24 (114-23).

149

Harashima C et al. Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome.
J. Comp. Neurol., 2006 Feb 10 , 494 (815-33).

150

Hüttmann K et al. Molecular and functional properties of neurons in the human lateral amygdala.
Mol. Cell. Neurosci., 2006 Feb , 31 (210-7).

151

Takahashi T et al. G protein-activated inwardly rectifying K+ channel inhibition and rescue of weaver mouse motor functions by antidepressants.
Neurosci. Res., 2006 Feb , 54 (104-11).

152

Dubinsky MC et al. Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression.
Am. J. Gastroenterol., 2006 Feb , 101 (360-7).

153

Kulik A et al. Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.
J. Neurosci., 2006 Apr 19 , 26 (4289-97).

154

Dhar MS et al. Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells.
BMC Physiol., 2006 , 6 (8).

155

Kobayashi T et al. G protein-activated inwardly rectifying potassium channels as potential therapeutic targets.
Curr. Pharm. Des., 2006 , 12 (4513-23).

156

Jaén C et al. Neuronal Kir3.1/Kir3.2a channels coupled to serotonin 1A and muscarinic m2 receptors are differentially modulated by the "short" RGS3 isoform.
Neuropharmacology, 2005 Sep , 49 (465-76).

157

Kanjhan R et al. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner.
J. Pharmacol. Exp. Ther., 2005 Sep , 314 (1353-61).

158

Brown SG et al. PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells.
Am. J. Physiol., Cell Physiol., 2005 Sep , 289 (C543-56).

159

Thompson L et al. Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.
J. Neurosci., 2005 Jul 6 , 25 (6467-77).

160

Cucullo L et al. Very low intensity alternating current decreases cell proliferation.
Glia, 2005 Jul , 51 (65-72).

161

Mendez I et al. Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease.
Brain, 2005 Jul , 128 (1498-510).

162

Clancy SM et al. Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex.
Mol. Cell. Neurosci., 2005 Feb , 28 (375-89).

163

Koyrakh L et al. Molecular and cellular diversity of neuronal G-protein-gated potassium channels.
J. Neurosci., 2005 Dec 7 , 25 (11468-78).

164

Costa AC et al. G-protein-gated potassium (GIRK) channels containing the GIRK2 subunit are control hubs for pharmacologically induced hypothermic responses.
J. Neurosci., 2005 Aug 24 , 25 (7801-4).

165

Marker CL et al. Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids.
J. Neurosci., 2005 Apr 6 , 25 (3551-9).

166

Koike-Tani M et al. Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel.
J. Physiol. (Lond.), 2005 Apr 15 , 564 (489-500).

167

Mutneja M et al. Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells.
Pflugers Arch., 2005 Apr , 450 (61-73).

168

Schein JC et al. The effect of GIRK2(wv) on neurite growth, protein expression, and viability in the CNS-derived neuronal cell line, CATH.A-differentiated.
Neuroscience, 2005 , 134 (21-32).

169

Plummer HK et al. Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.
BMC Cancer, 2005 , 5 (104).

170

Shankar H et al. Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.
Blood, 2004 Sep 1 , 104 (1335-43).

171

Filippov AK et al. Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors.
Mol. Pharmacol., 2004 Sep , 66 (468-77).

172

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Neuropsychopharmacology, 2004 Oct , 29 (1841-51).

173

Kobayashi T et al. Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users.
Ann. N. Y. Acad. Sci., 2004 Oct , 1025 (590-4).

174

Pil J et al. Synthesis and electrophysiological characterization of cyclic morphiceptin analogues.
Biochem. Pharmacol., 2004 May 15 , 67 (1887-95).

175

Bichet D et al. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity.
Proc. Natl. Acad. Sci. U.S.A., 2004 Mar 30 , 101 (4441-6).

176

Kawano T et al. Single-cell RT-PCR analysis of GIRK channels expressed in rat locus coeruleus and nucleus basalis neurons.
Neurosci. Lett., 2004 Mar 18 , 358 (63-7).

177

Marker CL et al. Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.
J. Neurosci., 2004 Mar 17 , 24 (2806-12).

178

Finley M et al. betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation.
J. Physiol. (Lond.), 2004 Mar 16 , 555 (643-57).

179

Ferrando-Miguel R et al. Protein levels of genes encoded on chromosome 21 in fetal Down Syndrome brain (Part V): overexpression of phosphatidyl-inositol-glycan class P protein (DSCR5).
Amino Acids, 2004 Jun , 26 (255-61).

180

Kurachi Y et al. Cell signal control of the G protein-gated potassium channel and its subcellular localization.
J. Physiol. (Lond.), 2004 Jan 15 , 554 (285-94).

181

Plummer HK et al. Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines.
BMC Cancer, 2004 Dec 16 , 4 (93).

182

Guatteo E et al. Voltage-gated calcium channels mediate intracellular calcium increase in weaver dopaminergic neurons during stimulation of D2 and GABAB receptors.
J. Neurophysiol., 2004 Dec , 92 (3368-74).

183

Ponomarev I et al. Convergent analysis of cDNA and short oligomer microarrays, mouse null mutants and bioinformatics resources to study complex traits.
Genes Brain Behav., 2004 Dec , 3 (360-8).

184

Milovic S et al. The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.
J. Biol. Chem., 2004 Aug 13 , 279 (34240-9).

185

Chen L et al. Inwardly rectifying potassium channels in rat retinal ganglion cells.
Eur. J. Neurosci., 2004 Aug , 20 (956-64).

186

Ivanina T et al. Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.
J. Biol. Chem., 2004 Apr 23 , 279 (17260-8).

187

Leaney JL Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein-gated inwardly rectifying potassium currents in cultured hippocampal neurons.
Eur. J. Neurosci., 2003 Oct , 18 (2110-8).

188

Zhao Q et al. Interaction of G protein beta subunit with inward rectifier K(+) channel Kir3.
Mol. Pharmacol., 2003 Nov , 64 (1085-91).

189

Drenhaus U et al. On the development of the stratification of the inner plexiform layer in the chick retina.
J. Comp. Neurol., 2003 May 19 , 460 (1-12).

190

Morgan AD et al. Decreased cocaine self-administration in Kir3 potassium channel subunit knockout mice.
Neuropsychopharmacology, 2003 May , 28 (932-8).

191

Gerstin KM et al. Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration.
Anesth. Analg., 2003 May , 96 (1345-9, table of contents).

192

Geisler S et al. Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat.
J. Comp. Neurol., 2003 Mar 24 , 458 (78-97).

193

Pil J et al. Serine 329 of the mu-opioid receptor interacts differently with agonists.
J. Pharmacol. Exp. Ther., 2003 Mar , 304 (924-30).

194

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).
Br. J. Pharmacol., 2003 Mar , 138 (1119-28).

195

Davila V et al. D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons.
J. Neurosci., 2003 Jul 2 , 23 (5693-7).

196

Blednov YA et al. A pervasive mechanism for analgesia: activation of GIRK2 channels.
Proc. Natl. Acad. Sci. U.S.A., 2003 Jan 7 , 100 (277-82).

197

Mitrovic I et al. Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences.
Proc. Natl. Acad. Sci. U.S.A., 2003 Jan 7 , 100 (271-6).

198

Fairchild G et al. Acute and chronic effects of corticosterone on 5-HT1A receptor-mediated autoinhibition in the rat dorsal raphe nucleus.
Neuropharmacology, 2003 Dec , 45 (925-34).

199

Ivanina T et al. Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel.
J. Biol. Chem., 2003 Aug 1 , 278 (29174-83).

200

Hill KG et al. Reduced ethanol-induced conditioned taste aversion and conditioned place preference in GIRK2 null mutant mice.
Psychopharmacology (Berl.), 2003 Aug , 169 (108-14).

201

Bertrand S et al. Different actions of gabapentin and baclofen in hippocampus from weaver mice.
, 2003 , 13 (525-8).

202

Mathie A et al. What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?
Cerebellum, 2003 , 2 (11-25).

203

Thiery E et al. Chromosome 21 KIR channels in brain development.
J. Neural Transm. Suppl., 2003 , (105-15).

204

Ikeda K et al. Molecular mechanisms of analgesia induced by opioids and ethanol: is the GIRK channel one of the keys?
Neurosci. Res., 2002 Oct , 44 (121-131).

205

Peng J et al. Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype.
J. Biol. Chem., 2002 Nov 15 , 277 (44285-91).

206

Suda S et al. Potassium channel mRNAs with AU-rich elements and brain-specific expression.
Biochem. Biophys. Res. Commun., 2002 Mar 15 , 291 (1265-71).

207

Chen L et al. A glutamate residue at the C terminus regulates activity of inward rectifier K+ channels: implication for Andersen's syndrome.
Proc. Natl. Acad. Sci. U.S.A., 2002 Jun 11 , 99 (8430-5).

208

Connors NC et al. Dystrophin Dp71 is critical for the clustered localization of potassium channels in retinal glial cells.
J. Neurosci., 2002 Jun 1 , 22 (4321-7).

209

Torrecilla M et al. G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.
J. Neurosci., 2002 Jun 1 , 22 (4328-34).

210

Harkins AB et al. Cell death in weaver mouse cerebellum.
Cerebellum, 2002 Jul , 1 (201-6).

211

Kobayashi T et al. Functional characterization of an endogenous Xenopus oocyte adenosine receptor.
Br. J. Pharmacol., 2002 Jan , 135 (313-22).

212

Wickman K et al. Structural characterization of the mouse Girk genes.
Gene, 2002 Feb 6 , 284 (241-50).

213

Ma D et al. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart.
Neuron, 2002 Feb 28 , 33 (715-29).

214

Brochiero E et al. Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.
Am. J. Physiol. Renal Physiol., 2002 Feb , 282 (F289-300).

215

Blednov YA et al. Hyperactivity and dopamine D1 receptor activation in mice lacking girk2 channels.
Psychopharmacology (Berl.), 2002 Feb , 159 (370-8).

216

Marker CL et al. Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice.
Neuroreport, 2002 Dec 20 , 13 (2509-13).

217

Guo Y et al. A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating.
J. Biol. Chem., 2002 Dec 13 , 277 (48289-94).

218

Zhang Q et al. Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.
J. Physiol. (Lond.), 2002 Dec 1 , 545 (355-73).

219

Chioza B et al. Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes.
Epilepsy Res., 2002 Dec , 52 (107-16).

220

Wickenden AD Potassium channels as anti-epileptic drug targets.
Neuropharmacology, 2002 Dec , 43 (1055-60).

221

Leaney JL et al. A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits.
J. Biol. Chem., 2002 Aug 9 , 277 (28803-9).

222

Simon J et al. Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells.
J. Biol. Chem., 2002 Aug 30 , 277 (31390-400).

223

Ozaki M et al. Degeneration of pontine mossy fibres during cerebellar development in weaver mutant mice.
Eur. J. Neurosci., 2002 Aug , 16 (565-74).

224

Leverson JD et al. The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.
Mol. Biol. Cell, 2002 Apr , 13 (1132-43).

225

Blednov YA et al. GIRK2 deficient mice. Evidence for hyperactivity and reduced anxiety.
Physiol. Behav., 2001 Sep 1-15 , 74 (109-17).

226

Yi BA et al. Controlling potassium channel activities: Interplay between the membrane and intracellular factors.
Proc. Natl. Acad. Sci. U.S.A., 2001 Sep 25 , 98 (11016-23).

227

Pil J et al. The role of the hydrophilic Asn230 residue of the mu-opioid receptor in the potency of various opioid agonists.
Br. J. Pharmacol., 2001 Oct , 134 (496-506).

228

Mascia MP et al. Does acetaldehyde mediate ethanol action in the central nervous system?
Alcohol. Clin. Exp. Res., 2001 Nov , 25 (1570-5).

229

Rogalski SL et al. Eicosanoids inhibit the G-protein-gated inwardly rectifying potassium channel (Kir3) at the Na+/PIP2 gating site.
J. Biol. Chem., 2001 May 4 , 276 (14855-60).

230

Zhou W et al. Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels.
Proc. Natl. Acad. Sci. U.S.A., 2001 May 22 , 98 (6482-7).

231

Salvador C et al. Functional properties of a truncated recombinant GIRK5 potassium channel.
Biochim. Biophys. Acta, 2001 May 2 , 1512 (135-47).

232

Yi BA et al. Yeast screen for constitutively active mutant G protein-activated potassium channels.
Neuron, 2001 Mar , 29 (657-67).

233

Yamakura T et al. Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels.
Anesthesiology, 2001 Jul , 95 (144-53).

234

Slesinger PA Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels.
Biophys. J., 2001 Feb , 80 (707-18).

235

Inanobe A et al. Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel.
J. Physiol. (Lond.), 2001 Aug 15 , 535 (133-43).

236

Blednov YA et al. Potassium channels as targets for ethanol: studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice.
J. Pharmacol. Exp. Ther., 2001 Aug , 298 (521-30).

237

Weigl LG et al. G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics.
Mol. Pharmacol., 2001 Aug , 60 (282-9).

238

Li JH et al. The expression of G-protein-gated inwardly rectifying K+ channels GIRK1 and GIRK2 mRNAs in the supraoptic nucleus of the rat and possible role involved.
Neuroreport, 2001 Apr 17 , 12 (1007-10).

239

Ulens C et al. Changes in GIRK1/GIRK2 deactivation kinetics and basal activity in the presence and absence of RGS4.
Life Sci., 2000 Sep 29 , 67 (2305-17).

240

Medina I et al. A switch mechanism for G beta gamma activation of I(KACh).
J. Biol. Chem., 2000 Sep 22 , 275 (29709-16).

241

Ulens C et al. Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity.
J. Pharmacol. Exp. Ther., 2000 Sep , 294 (1024-33).

242

Mark MD et al. G-protein mediated gating of inward-rectifier K+ channels.
Eur. J. Biochem., 2000 Oct , 267 (5830-6).

243

Jelacic TM et al. Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3.
J. Biol. Chem., 2000 Nov 17 , 275 (36211-6).

244

Xu H et al. Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels.
Am. J. Physiol., Cell Physiol., 2000 Nov , 279 (C1464-71).

245

Müllner C et al. Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase.
J. Gen. Physiol., 2000 May , 115 (547-58).

246

Hou P et al. Impermeability of the GIRK2 weaver channel to divalent cations.
Am. J. Physiol., Cell Physiol., 2000 May , 278 (C1038-46).

247

Wulfsen I et al. Expression of mRNA for voltage-dependent and inward-rectifying K channels in GH3/B6 cells and rat pituitary.
J. Neuroendocrinol., 2000 Mar , 12 (263-72).

248

Kuzhikandathil EV et al. Dominant-negative mutants identify a role for GIRK channels in D3 dopamine receptor-mediated regulation of spontaneous secretory activity.
J. Gen. Physiol., 2000 Jun , 115 (697-706).

249

Hibino H et al. Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain.
EMBO J., 2000 Jan 4 , 19 (78-83).

250

Leaney JL et al. The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K(+) channels.
J. Biol. Chem., 2000 Jan 14 , 275 (921-9).

251

Nehring RB et al. Neuronal inwardly rectifying K(+) channels differentially couple to PDZ proteins of the PSD-95/SAP90 family.
J. Neurosci., 2000 Jan 1 , 20 (156-62).

252

Hallmann K et al. Mutation analysis of the inwardly rectifying K(+) channels KCNJ6 (GIRK2) and KCNJ3 (GIRK1) in juvenile myoclonic epilepsy.
Am. J. Med. Genet., 2000 Feb 7 , 96 (8-11).

253

Bradley KK et al. Kir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytes.
Am. J. Physiol. Gastrointest. Liver Physiol., 2000 Feb , 278 (G289-96).

254

Rogalski SL et al. TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel.
J. Biol. Chem., 2000 Aug 18 , 275 (25082-8).

255

Guatteo E et al. The weaver mutation reverses the function of dopamine and GABA in mouse dopaminergic neurons.
J. Neurosci., 2000 Aug 15 , 20 (6013-20).

256

Wickman K et al. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4.
J. Neurosci., 2000 Aug 1 , 20 (5608-15).

257

Liesi P et al. Involvement of GIRK2 in postnatal development of the weaver cerebellum.
J. Neurosci. Res., 2000 Apr 15 , 60 (164-73).

258

Harkins AB et al. Evidence of elevated intracellular calcium levels in weaver homozygote mice.
J. Physiol. (Lond.), 2000 Apr 15 , 524 Pt 2 (447-55).

259

Kobayashi T et al. Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes.
Br. J. Pharmacol., 2000 Apr , 129 (1716-22).

260

Jensen P et al. Rescue of cerebellar granule cells from death in weaver NR1 double mutants.
J. Neurosci., 1999 Sep 15 , 19 (7991-8).

261

Liss B et al. The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels.
J. Neurosci., 1999 Oct 15 , 19 (8839-48).

262

Hou P et al. The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype.
J. Neurosci., 1999 Oct 1 , 19 (8327-36).

263

Yoon HJ et al. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events.
Proc. Natl. Acad. Sci. U.S.A., 1999 Nov 9 , 96 (13208-13).

264

Inanobe A et al. Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis.
J. Physiol. (Lond.), 1999 Nov 15 , 521 Pt 1 (19-30).

265

Ho IH et al. Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels.
J. Physiol. (Lond.), 1999 Nov 1 , 520 Pt 3 (645-51).

266

Jelacic TM et al. Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3.
J. Membr. Biol., 1999 May 15 , 169 (123-9).

267

Pei Q et al. Alteration in expression of G-protein-activated inward rectifier K+-channel subunits GIRK1 and GIRK2 in the rat brain following electroconvulsive shock.
Neuroscience, 1999 May , 90 (621-7).

268

Ho IH et al. Molecular determinants for sodium-dependent activation of G protein-gated K+ channels.
J. Biol. Chem., 1999 Mar 26 , 274 (8639-48).

269

Fernández-Fernández JM et al. Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones.
J. Physiol. (Lond.), 1999 Mar 15 , 515 ( Pt 3) (631-7).

270

Stevens EB et al. Bombesin receptors inhibit G protein-coupled inwardly rectifying K+ channels expressed in Xenopus oocytes through a protein kinase C-dependent pathway.
Mol. Pharmacol., 1999 Jun , 55 (1020-7).

271

Raymond V et al. DmGluRA, a Drosophila metabotropic glutamate receptor, activates G-protein inwardly rectifying potassium channels in Xenopus oocytes.
Neurosci. Lett., 1999 Jul 2 , 269 (1-4).

272

Kennedy ME et al. GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels.
J. Biol. Chem., 1999 Jan 22 , 274 (2571-82).

273

Yoshimoto Y et al. Somatostatin induces hyperpolarization in pancreatic islet alpha cells by activating a G protein-gated K+ channel.
FEBS Lett., 1999 Feb 12 , 444 (265-9).

274

Inanobe A et al. Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.
J. Neurosci., 1999 Feb 1 , 19 (1006-17).

275

Ulens C et al. The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands.
Eur. J. Pharmacol., 1999 Dec 3 , 385 (239-45).

276

Kawano T et al. Importance of the G protein gamma subunit in activating G protein-coupled inward rectifier K(+) channels.
FEBS Lett., 1999 Dec 17 , 463 (355-9).

277

Lewohl JM et al. G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action.
Nat. Neurosci., 1999 Dec , 2 (1084-90).

278

Kobayashi T et al. Ethanol opens G-protein-activated inwardly rectifying K+ channels.
Nat. Neurosci., 1999 Dec , 2 (1091-7).

279

Blum M et al. The weaver GIRK2 mutation leads to decreased levels of serum thyroid hormone: characterization of the effect on midbrain dopaminergic neuron survival.
Exp. Neurol., 1999 Dec , 160 (413-24).

280

Schoots O et al. Co-expression of human Kir3 subunits can yield channels with different functional properties.
Cell. Signal., 1999 Dec , 11 (871-83).

281

Muma NA et al. Corticosteroids alter G protein inwardly rectifying potassium channels protein levels in hippocampal subfields.
Brain Res., 1999 Aug 28 , 839 (331-5).

282

Migheli A et al. A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum.
Am. J. Pathol., 1999 Aug , 155 (365-73).

283

Womack M et al. Elevated intracellular calcium levels in cerebellar granule neurons of weaver mice.
Neuroreport, 1998 Oct 26 , 9 (3391-5).

284

Corey S et al. Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers.
J. Biol. Chem., 1998 Oct 16 , 273 (27499-504).

285

Takano M et al. Cytoplasmic terminus domains of Kir6.x confer different nucleotide-dependent gating on the ATP-sensitive K+ channel.
J. Physiol. (Lond.), 1998 Oct 15 , 512 ( Pt 2) (395-406).

286

Rossi P et al. The weaver mutation causes a loss of inward rectifier current regulation in premigratory granule cells of the mouse cerebellum.
J. Neurosci., 1998 May 15 , 18 (3537-47).

287

Oliver D et al. Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels.
Biophys. J., 1998 May , 74 (2318-26).

288

Uezono Y et al. Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes.
Neuroreport, 1998 Mar 9 , 9 (583-7).

289

Jarolimek W et al. Pore mutation in a G-protein-gated inwardly rectifying K+ channel subunit causes loss of K+-dependent inhibition in weaver hippocampus.
J. Neurosci., 1998 Jun 1 , 18 (4001-7).

290

Huang CL et al. Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma.
Nature, 1998 Feb 19 , 391 (803-6).

291

Schein JC et al. Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver.
Dev. Biol., 1998 Dec 15 , 204 (432-50).

292

Fox AP et al. Altered responses to potassium in cerebellar neurons from weaver heterozygote mice.
, 1998 Dec , 123 (298-306).

293

Kuzhikandathil EV et al. Human dopamine D3 and D2L receptors couple to inward rectifier potassium channels in mammalian cell lines.
Mol. Cell. Neurosci., 1998 Dec , 12 (390-402).

294

Wei J et al. Characterization of murine Girk2 transcript isoforms: structure and differential expression.
Genomics, 1998 Aug 1 , 51 (379-90).

295

Stevens EB et al. Identification of regions that regulate the expression and activity of G protein-gated inward rectifier K+ channels in Xenopus oocytes.
J. Physiol. (Lond.), 1997 Sep 15 , 503 ( Pt 3) (547-62).

296

Gosset P et al. A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1).
Genomics, 1997 Sep 1 , 44 (237-41).

297

Murer G et al. An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain.
Neuroscience, 1997 Sep , 80 (345-57).

298

Lüscher C et al. G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons.
Neuron, 1997 Sep , 19 (687-95).

299

Slesinger PA et al. Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice.
Proc. Natl. Acad. Sci. U.S.A., 1997 Oct 28 , 94 (12210-7).

300

Chan KW et al. Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity.
J. Biol. Chem., 1997 Mar 7 , 272 (6548-55).

301

Adelbrecht C et al. An immunocytochemical study of a G-protein-gated inward rectifier K+ channel (GIRK2) in the weaver mouse mesencephalon.
Neuroreport, 1997 Mar 3 , 8 (969-74).

302

Ehrengruber MU et al. Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons.
Proc. Natl. Acad. Sci. U.S.A., 1997 Jun 24 , 94 (7070-5).

303

Pfaff T et al. Expression cloning of rat cerebellar adenosine A1 receptor by coupling to Kir channels.
Neuroreport, 1997 Jul 28 , 8 (2455-60).

304

Wei J et al. In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice.
J. Neuropathol. Exp. Neurol., 1997 Jul , 56 (762-71).

305

Ohira M et al. Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21.
Genome Res., 1997 Jan , 7 (47-58).

306

Signorini S et al. Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2.
Proc. Natl. Acad. Sci. U.S.A., 1997 Feb 4 , 94 (923-7).

307

Schoots O et al. Genomic organization and promoter analysis of the human G-protein-coupled K+ channel Kir3.1 (KCNJ3/HGIRK1).
Genomics, 1997 Feb 1 , 39 (279-88).

308

Chen SC et al. Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse.
Brain Res., 1997 Dec 19 , 778 (251-64).

309

Lauritzen I et al. Comparative expression of the inward rectifier K+ channel GIRK2 in the cerebellum of normal and weaver mutant mice.
Brain Res., 1997 Apr 4 , 753 (8-17).

310

Woodward R et al. Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels.
J. Biol. Chem., 1997 Apr 18 , 272 (10823-30).

311

Huang CL et al. Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels.
FEBS Lett., 1997 Apr 1 , 405 (291-8).

312

Sharon D et al. Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes.
J. Gen. Physiol., 1997 Apr , 109 (477-90).

313

Bjerregaard A et al. Weaver mutant mouse cerebellar granule cells respond normally to chronic depolarization.
Int. J. Dev. Neurosci., 1997 Apr , 15 (155-62).

314

Wischmeyer E et al. Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels.
Mol. Cell. Neurosci., 1997 , 9 (194-206).

315

Karschin C et al. Ontogeny of gene expression of Kir channel subunits in the rat.
Mol. Cell. Neurosci., 1997 , 10 (131-48).

316

Fakler B et al. Heterooligomeric assembly of inward-rectifier K+ channels from subunits of different subfamilies: Kir2.1 (IRK1) and Kir4.1 (BIR10).
Pflugers Arch., 1996 Nov-Dec , 433 (77-83).

317

Surmeier DJ et al. The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells.
Proc. Natl. Acad. Sci. U.S.A., 1996 Oct 1 , 93 (11191-5).

318

Chan KW et al. Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit.
Proc. Natl. Acad. Sci. U.S.A., 1996 Nov 26 , 93 (14193-8).

319

Liao YJ et al. Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain.
J. Neurosci., 1996 Nov 15 , 16 (7137-50).

320

Kofuji P et al. Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells.
Neuron, 1996 May , 16 (941-52).

321

Navarro B et al. Nonselective and G betagamma-insensitive weaver K+ channels.
Science, 1996 Jun 28 , 272 (1950-3).

322

Kubo Y et al. A weakly inward rectifying potassium channel of the salmon brain. Glutamate 179 in the second transmembrane domain is insufficient for strong rectification.
J. Biol. Chem., 1996 Jun 28 , 271 (15729-35).

323

Bandmann O et al. The human homologue of the weaver mouse gene in familial and sporadic Parkinson's disease.
Neuroscience, 1996 Jun , 72 (877-9).

324

Tong Y et al. The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2.
FEBS Lett., 1996 Jul 15 , 390 (63-8).

325

Isomoto S et al. A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes.
Biochem. Biophys. Res. Commun., 1996 Jan 5 , 218 (286-91).

326

Velimirovic BM et al. The K+ channel inward rectifier subunits form a channel similar to neuronal G protein-gated K+ channel.
FEBS Lett., 1996 Jan 22 , 379 (31-7).

327

Fink M et al. Dominant negative chimeras provide evidence for homo and heteromultimeric assembly of inward rectifier K+ channel proteins via their N-terminal end.
FEBS Lett., 1996 Jan 2 , 378 (64-8).

328

Nelson CS et al. Melatonin receptors activate heteromeric G-protein coupled Kir3 channels.
Neuroreport, 1996 Feb 29 , 7 (717-20).

329

Slesinger PA et al. Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels.
Neuron, 1996 Feb , 16 (321-31).

330

Silverman SK et al. A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation.
Proc. Natl. Acad. Sci. U.S.A., 1996 Dec 24 , 93 (15429-34).

331

Cohen NA et al. Inhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunits.
J. Biol. Chem., 1996 Dec 13 , 271 (32301-5).

332

Tanizawa Y et al. A human pancreatic islet inwardly rectifying potassium channel: cDNA cloning, determination of the genomic structure and genetic variations in Japanese NIDDM patients.
Diabetologia, 1996 Apr , 39 (447-52).

333

Dixon AK et al. Distribution of mRNA encoding the inwardly rectifying K+ channel, BIR1 in rat tissues.
FEBS Lett., 1995 Oct 23 , 374 (135-40).

334

Ferrer J et al. Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels.
J. Biol. Chem., 1995 Nov 3 , 270 (26086-91).

335

Doi T et al. Subunit-specific inhibition of inward-rectifier K+ channels by quinidine.
FEBS Lett., 1995 Nov 20 , 375 (193-6).

336

Tsaur ML et al. Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM.
Diabetes, 1995 May , 44 (592-6).

337

Pessia M et al. Contributions of the C-terminal domain to gating properties of inward rectifier potassium channels.
Neuron, 1995 May , 14 (1039-45).

338

Kobayashi T et al. Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain.
Biochem. Biophys. Res. Commun., 1995 Mar 28 , 208 (1166-73).

339

Sakura H et al. Characterization and variation of a human inwardly-rectifying-K-channel gene (KCNJ6): a putative ATP-sensitive K-channel subunit.
FEBS Lett., 1995 Jun 26 , 367 (193-7).

340

Bond CT et al. Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain.
FEBS Lett., 1995 Jun 19 , 367 (61-6).

341

Kofuji P et al. Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers.
Proc. Natl. Acad. Sci. U.S.A., 1995 Jul 3 , 92 (6542-6).

342

Duprat F et al. Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers.
Biochem. Biophys. Res. Commun., 1995 Jul 17 , 212 (657-63).

343

Lesage F et al. Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.
J. Biol. Chem., 1995 Dec 1 , 270 (28660-7).

344

Mjaatvedt AE et al. Assessment of a mutation in the H5 domain of Girk2 as a candidate for the weaver mutation.
Genome Res., 1995 Dec , 5 (453-63).

345

Glowatzki E et al. Subunit-dependent assembly of inward-rectifier K+ channels.
Proc. Biol. Sci., 1995 Aug 22 , 261 (251-61).

346

Lesage F et al. Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain.
FEBS Lett., 1994 Oct 10 , 353 (37-42).

347

Fakler B et al. A structural determinant of differential sensitivity of cloned inward rectifier K+ channels to intracellular spermine.
FEBS Lett., 1994 Dec 19 , 356 (199-203).