Referenced in: none

Automatically associated channels: Kv1.5

Title: Synthesis and evaluation of (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones as Kv1.5 channel blockers for the treatment of atrial fibrillation.

Authors: Benjamin E Blass, Keith Coburn, Wenlin Lee, Neil Fairweather, Andrew Fluxe, Shengde Wu, John M Janusz, Michael Murawsky, Gina M Fadayel, Bin Fang, Michelle Hare, Jim Ridgeway, Ron White, Chris Jackson, Laurent Djandjighian, Richard Hedges, Fred C Wireko, Amanda L Ritter

Journal, date & volume: Bioorg. Med. Chem. Lett., 2006 Sep 1 , 16, 4629-32

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/16793267

Abstract
A series of novel (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones were prepared and examined for utility as Kv1.5 channel blockers for the treatment of atrial fibrillation.