Channelpedia

PubMed 17462888


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kv1.5



Title: Benzopyran sulfonamides as KV1.5 potassium channel blockers.

Authors: John Lloyd, Karnail S Atwal, Heather J Finlay, Michael Nyman, Tram Huynh, Rao Bhandaru, Alexander Kover, Joan Schmidt, Wayne Vaccaro, Mary Lee Conder, Tonya Jenkins-West, Paul Levesque

Journal, date & volume: Bioorg. Med. Chem. Lett., 2007 Jun 15 , 17, 3271-5

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/17462888


Abstract
K(V)1.5 blockers have the potential to be atrium-selective agents for treatment of atrial fibrillation. The benzopyrans provide a template for the synthesis of potent and selective K(V)1.5 blockers.