Referenced in: none

Automatically associated channels: Kv7.1

Title: The KCNQ1 potassium channel: from gene to physiological function.

Authors: Thomas Jespersen, Morten Grunnet, Søren-Peter Olesen

Journal, date & volume: , 2005 Dec , 20, 408-16

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/16287990

Abstract
The voltage-gated KCNQ1 (KvLQT1, Kv7.1) potassium channel plays a crucial role in shaping the cardiac action potential as well as in controlling the water and salt homeostasis in several epithelial tissues. KCNQ1 channels in these tissues are tightly regulated by auxiliary proteins and accessory factors, capable of modulating the properties of the channel complexes. This paper reviews the current knowledge about the KCNQ1 channel with a major focus on interacting proteins and physiological functions.