Referenced in: none

Automatically associated channels: Kv11.1 , Kv7.1 , Kv7.2 , Kv7.4

Title: Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator.

Authors: Margrith E Mattmann, Haibo Yu, Zhihong Lin, Kaiping Xu, Xiaofang Huang, Shunyou Long, Meng Wu, Owen B McManus, Darren W Engers, Uyen M Le, Min Li, Craig W Lindsley, Corey R Hopkins

Journal, date & volume: Bioorg. Med. Chem. Lett., 2012 Sep 15 , 22, 5936-41

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22910039

Abstract