Referenced in: none

Automatically associated channels: TRP , TRPC

Title: TRP Channels in Reproductive (Neuro)Endocrinology.

Authors: Trese Leinders-Zufall, Ulrich Boehm

Journal, date & volume: Handb Exp Pharmacol, 2014 , 223, 1107-18

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24961982

Abstract
Transient receptor potential (TRP) ion channels have been detected in neurons that are part of the neural network controlling reproductive physiology and behavior. In this chapter we will primarily take a look at the classical/canonical TRP (TRPC) channels but will also examine some other members of the TRP channel superfamily in reproductive (neuro)endocrinology. The referenced data suggest that different TRP proteins could play functional roles at different levels of the reproductive pathway. Still, our understanding of TRP channel involvement in (neuro)endocrinology is quite limited. Due to their mechanism of activation and complex regulation, these channels are however ideally suited to be part of the transduction machinery of hormone-secreting cells.