Referenced in: none

Automatically associated channels: Nav1.5

Title: Assignment of the human heart tetrodotoxin-resistant voltage-gated Na+ channel alpha-subunit gene (SCN5A) to band 3p21.

Authors: A L George, T A Varkony, H A Drabkin, J Han, J F Knops, W H Finley, G B Brown, D C Ward, M Haas

Journal, date & volume: Cytogenet. Cell Genet., 1995 , 68, 67-70

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/7956363

Abstract
The chromosomal location of SCN5A, the gene encoding the principal voltage-gated Na+ channel expressed in human heart, has been determined by three independent methodologies: somatic cell hybrid mapping, chromosomal microdissection-polymerase chain reaction, and fluorescence in situ hybridization. The SCN5A gene was assigned to the short arm of chromosome 3 (band 3p21) by all three approaches. These data are further evidence that striated muscle Na+ channel genes are dispersed in the genome.