Referenced in: none

Automatically associated channels: SK2 , TRP , TRPV , TRPV4

Title: An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.

Authors: Kevin S Thorneloe, Mui Cheung, Weike Bao, Hasan Alsaid, Stephen Lenhard, Ming-Yuan Jian, Melissa Costell, Kristeen Maniscalco-Hauk, John A Krawiec, Alan Olzinski, Earl Gordon, Irina Lozinskaya, Lou Elefante, Pu Qin, Daniel S Matasic, Chris James, James Tunstead, Brian Donovan, Lorena Kallal, Anna Waszkiewicz, Kalindi Vaidya, Elizabeth A Davenport, Jonathan Larkin, Mark Burgert, Linda N Casillas, Robert W Marquis, Guosen Ye, Hilary S Eidam, Krista B Goodman, John R Toomey, Theresa J Roethke, Beat M Jucker, Christine G Schnackenberg, Mary I Townsley, John J Lepore, Robert N Willette

Journal, date & volume: Sci Transl Med, 2012 Nov 7 , 4, 159ra148

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/23136043

Abstract