Channelpedia

PubMed 23800054


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: TRP , TRPV , TRPV3



Title: TRPV3: a 'more than skinny' channel.

Authors: Bernd Nilius, Tamás Bíró

Journal, date & volume: Exp. Dermatol., 2013 Jul , 22, 447-52

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/23800054


Abstract
The skin is our largest organ serving different tasks from barrier formation through somatosensing to hair development. Recently, members of the large trp (Transient Receptor Potential, TRP) gene family encoding proteins that form cation selective ion channel have been identified to play a crucial role in skin functions. Within the 28 different mammalian TRP channels, TRPV3 might be the most important member in the skin. This review gives an overview on functional properties of TRPV3 in skin physiology and in certain skin diseases.