Channelpedia

PubMed 1335956


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Cav1.1



Title: The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.

Authors: H Chin, M Krall, H L Kim, C A Kozak, B Mock

Journal, date & volume: Genomics, 1992 Dec , 14, 1089-91

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/1335956


Abstract
Cchl1a3 encodes the dihydropyridine-sensitive calcium channel alpha 1 subunit isoform predominantly expressed in skeletal muscle. mdg (muscular dysgenesis) has previously been implicated as a mutant allele of this gene. Hybridization of a rat brain cDNA probe for Cchl1a3 to Southern blots of DNAs from a panel of Chinese hamster x mouse somatic cell hybrids suggested that this gene maps to mouse Chromosome 1. Analysis of the progeny of an inbred strain cross-positioned Cchl1a3 1.3 cM proximal to the Pep-3 locus on Chr 1.