Referenced in: none

Automatically associated channels: Cav1.1 , Slo1

Title: The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.

Authors: B Drouet, L García, D Simon-Chazottes, M G Mattei, J L Guénet, A Schwartz, G Varadi, M Pincon-Raymond

Journal, date & volume: Mamm. Genome, 1993 Sep , 4, 499-503

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/8118099

Abstract
Using both chromosomal in situ hybridization and molecular techniques, we report the genetic localization of the gene coding for the alpha 1 subunit of the skeletal slow Ca2+ current channel/DHP receptor gene (Cchl1a3) on human Chromosome (Chr) 1 (1q31-1q32 region) and on mouse Chr 1 (region (F-G)). On the basis of single-strand conformation polymorphism (SSCP-PCR) analysis in an interspecific backcross, we have determined that the Cchl1a3 = mdg (muscular dysgenesis) locus is very closely linked to the myogenin (Myog) locus.