Referenced in: none

Automatically associated channels: Kv2.1

Title: Shab gene expression in identified neurons of the pyloric network in the lobster stomatogastric ganglion.

Authors: D J Baro, C L Cole, A R Zarrin, S Hughes, R M Harris-Warrick

Journal, date & volume: Recept. Channels, 1994 , 2, 193-205

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/7874446

Abstract
A single shab gene exists in the lobster, Panulirus interruptus, and undergoes alternate splicing to produce multiple transcripts. Using in situ hybridization we have determined the expression pattern of the shab gene in identified neurons of the pyloric network. The shab gene is consistently expressed at a low level in the Ventricular Dilator cell, a high level in the Pyloric Dilator cell, and is not detectably expressed in the Lateral Pyloric or Inferior Cardiac cells. Shab gene expression in the Anterior Burster cell varies from animal to animal. The electrophysiologically heterogeneous group of eight Pyloric Constrictor cells also shows differences in shab gene expression. These results support the idea that differences in shab gene expression contribute to the unique electrophysiological phenotypes displayed by each cell type.